valine and Pain

valine has been researched along with Pain in 51 studies

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-19905 (9.80)18.7374
1990's9 (17.65)18.2507
2000's22 (43.14)29.6817
2010's15 (29.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Asiri, YI; Fung, T; MacLeod, BA; Puil, E; Schwarz, SKW; Wall, R1
Ase, AR; Bonin, RP; Daou, I; De Koninck, Y; Longo, G; Mogil, JS; Ribeiro-da-Silva, A; Séguéla, P; Tuttle, AH; Wieskopf, JS; Wood, JN1
Ambite-Quesada, S; Caminero, AB; Fernández-de-las-Peñas, C; Gil-Crujera, A; Ortega-Santiago, R; Ortíz-Gutiérrez, R1
Borszcz, GS; Spuz, CA; Tomaszycki, ML1
Keegan, DA1
Chao, HT; Chen, LF; Hsieh, JC; Li, WC; Lin, MW; Low, I; Shen, HD; Tu, CH; Wei, SY1
Hosokawa, T; Ishida, S; Kimura, F; Nakajima, H; Tsukahara, A; Unoda, K1
Hill, GT; Lee, P; Matkovits, T; Moore, AY; Silverfield, JC; Sullivan-Bolyai, J; Tyring, SK1
Aihara, H; Tago, M; Yamashita, S1
Axelsson, S; Berg, T; Engström, M; Jonsson, L; Kanerva, M; Pitkäranta, A; Stjernquist-Desatnik, A1
Ingvar, M; Jensen, KB; Kosek, E; Lonsdorf, TB; Schalling, M1
Cooke, JE; Mathers, DA; Puil, E1
Chung, CC; MacLeod, BA; Puil, E; Ries, CR; Schwarz, SK; Wang, JT1
Janahmadi, M; Javan, M; Khakpay, R; Semnanian, S1
Allchorne, A; Barrett, LB; Belfer, I; Cobos, EJ; Coppola, G; Costigan, M; Dai, F; Diatchenko, L; Gershon, E; Geschwind, DH; Goldman, D; Griffin, RS; Karppinen, J; Kelempisioti, A; Kiselycznyk, C; Livneh, J; Lu, Y; Maixner, W; Männikkö, M; Max, MB; Nikolajsen, L; Poddar, M; Seltzer, Z; Shen, PH; Smith, S; Woolf, CJ; Wu, T; Zaykin, D1
Cooke, JE; MacLeod, BA; Puil, E; Putrenko, I; Ries, CR; Sallam, NA; Schwarz, SK; Wall, RA; Whitehead, RA1
Himichi, T; Kaneko, M; Nomura, A; Nomura, M; Nomura, Y; Okuma, Y1
Barone, Y; Coppola, G; Daverio, A; Di Lorenzo, C; Di Lorenzo, G; Giannoudas, I; Grieco, GS; Nicoletti, F; Niolu, C; Pascale, E; Pasqualetti, P; Pierelli, F; Santorelli, FM; Seri, S; Siracusano, A1
Wood, M1
Jubelt, B1
Hama, A; Sagen, J; Woon Lee, J1
Barber, J; Blatter, MM; Goldstein, D; Hill, J; Jones, TM; Schultz, M; Spruance, SL; Vargas-Cortes, M1
Bartels, EM; Bliddal, H; Danneskiold-Samsøe, B; Graff, LB; Kendall, SA; Krogsgaard, K; Malmskov, H; Schaadt, ML; Wittrup, I1
Lim, LS; Takahashi, PY1
Berger, IH; Bergman, BD; Martin, DP1
Baar, C; Dale, O; Kaasa, S; Klepstad, P; Krokan, HE; Kvam, TM; Rakvåg, TT; Skorpen, F1
Wassilew, SW1
Yonehara, N; Yoshimura, M1
Cheng, X; Dib-Hajj, SD; Tyrrell, L; Waxman, SG1
Andersen, PL; Beutner, KR; Forszpaniak, C; Friedman, DJ; Wood, MJ1
Austin, R; Berzon, RA; Dix, LP; Mauskopf, JA1
Corey, L; Douglas, JM; Esmann, J; Spruance, SL; Tyring, SK1
Crooks, RJ; Fiddian, AP; Shukla, S; Wood, MJ1
Buerkle, H; Khan, IM; Taylor, P; Yaksh, TL1
Goto, F; Ishizaki, K; Karasawa, S; Nara, T; Obata, H; Sasaki, M1
Gnann, JW; Whitley, RJ1
Bennett, AD; Everhart, AW; Hulsebosch, CE1
Helmstetter, FJ; Tershner, SA1
Decroix, J; Goh, CL; Gonzalez, R; Mobacken, H; Naisbett, B; Partsch, H; Shukla, S; Walsh, L1
Cochener, B; Colin, J; Hoang-Xuan, T; Lescale, O; Prisant, O; Rolland, B1
Gyermek, L; Hanaoka, K; Kawasaki-Yatsugi, S; Lee, C; Nishiyama, T; Yamaguchi, T1
García, A; García, I; García, S; Lanchares, JL; Sánchez, JA1
Bhave, G; Carlton, SM; Gereau , RW; Karim, F1
Hu, JY; Zhao, ZQ1
Mitchell, D; Sher, GD1
Bossut, D; Frenk, H; Mayer, DJ1
Davidoff, RA; Hackman, JC; Holohean, AM; Vega, JL1
Raigorodsky, G; Urca, G1
Caudle, RM; Isaac, L1
Abbott, FV; Connell, B; Franklin, KB1

Reviews

4 review(s) available for valine and Pain

ArticleYear
Understanding pain in herpes zoster: an essential for optimizing treatment.
    The Journal of infectious diseases, 2002, Oct-15, Volume: 186 Suppl 1

    Topics: 2-Aminopurine; Acyclovir; Analgesics; Antiviral Agents; Chronic Disease; Clinical Trials as Topic; Famciclovir; Herpes Zoster; Herpesvirus 3, Human; Humans; Meta-Analysis as Topic; Pain; Pain Measurement; Proportional Hazards Models; Treatment Outcome; Valacyclovir; Valine

2002
80-year-old man with fever and ear pain.
    Mayo Clinic proceedings, 2004, Volume: 79, Issue:8

    Topics: Acetates; Acyclovir; Age Factors; Aged; Aged, 80 and over; Amines; Analgesics; Antiviral Agents; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Earache; Fever; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Male; Oxycodone; Pain; Patient Selection; Polymerase Chain Reaction; Risk Factors; Valacyclovir; Valine

2004
[Varicella-zoster virus infections--2: Zoster pain -- therapy and prevention].
    MMW Fortschritte der Medizin, 2006, Volume: Spec no.1

    Topics: 2-Aminopurine; Acute Disease; Acyclovir; Administration, Oral; Adult; Age Factors; Analgesics, Non-Narcotic; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents, Tricyclic; Antiviral Agents; Bromodeoxyuridine; Child; Drug Therapy, Combination; Famciclovir; Female; Herpes Zoster; Herpesvirus 3, Human; Herpesvirus Vaccines; Humans; Male; Middle Aged; Neuralgia, Postherpetic; Pain; Prodrugs; Risk Factors; Sex Factors; Time Factors; Vaccination; Valacyclovir; Valine

2006
Therapeutic approaches to the management of herpes zoster.
    Advances in experimental medicine and biology, 1999, Volume: 458

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Famciclovir; Herpes Zoster; Humans; Pain; Prednisone; Prodrugs; Valacyclovir; Valine

1999

Trials

11 trial(s) available for valine and Pain

ArticleYear
FV-100 versus valacyclovir for the prevention of post-herpetic neuralgia and the treatment of acute herpes zoster-associated pain: A randomized-controlled trial.
    Journal of medical virology, 2017, Volume: 89, Issue:7

    Topics: Acyclovir; Aged; Aged, 80 and over; Antiviral Agents; Cost of Illness; Double-Blind Method; Female; Herpes Zoster; Humans; Male; Middle Aged; Neuralgia, Postherpetic; Pain; Pain Management; Prospective Studies; Pyrimidine Nucleosides; Valacyclovir; Valine

2017
The course of pain in Bell's palsy: treatment with prednisolone and valacyclovir.
    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2009, Volume: 30, Issue:6

    Topics: Acyclovir; Adult; Anti-Inflammatory Agents; Antiviral Agents; Bell Palsy; Double-Blind Method; Earache; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Neck Pain; Pain; Pain Measurement; Prednisolone; Prognosis; Prospective Studies; Treatment Outcome; Valacyclovir; Valine

2009
Valacyclovir and famciclovir therapy in herpes zoster.
    Current neurology and neuroscience reports, 2002, Volume: 2, Issue:6

    Topics: 2-Aminopurine; Acyclovir; Aged; Antiviral Agents; Double-Blind Method; Famciclovir; Gastrointestinal Diseases; Headache; Herpes Zoster; Humans; Middle Aged; Nausea; Neuralgia; Pain; Prospective Studies; Time Factors; Treatment Outcome; Valacyclovir; Valine

2002
High-dose, short-duration, early valacyclovir therapy for episodic treatment of cold sores: results of two randomized, placebo-controlled, multicenter studies.
    Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:3

    Topics: Acyclovir; Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Child; Double-Blind Method; Female; Herpes Labialis; Humans; Male; Middle Aged; Pain; Valacyclovir; Valine

2003
No effect of antiviral (valacyclovir) treatment in fibromyalgia: a double blind, randomized study.
    The Journal of rheumatology, 2004, Volume: 31, Issue:4

    Topics: Acyclovir; Administration, Oral; Antiviral Agents; Double-Blind Method; Female; Fibromyalgia; Humans; Joints; Male; Middle Aged; Pain; Pain Measurement; Sickness Impact Profile; Tablets; Valacyclovir; Valine

2004
Valaciclovir compared with acyclovir for improved therapy for herpes zoster in immunocompetent adults.
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:7

    Topics: Acyclovir; Administration, Oral; Aged; Aged, 80 and over; Analgesics; Antiviral Agents; Double-Blind Method; Drug Administration Schedule; Female; Herpes Zoster; Herpes Zoster Ophthalmicus; Humans; Immunocompetence; Male; Middle Aged; Neuralgia; Pain; Quality of Life; Valacyclovir; Valine

1995
Estimating the value of a generic quality-of-life measure.
    Medical care, 1995, Volume: 33, Issue:4 Suppl

    Topics: Acyclovir; Antiviral Agents; Double-Blind Method; Female; Herpes Zoster; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Pain; Prognosis; Quality of Life; Regression Analysis; Sleep; Valacyclovir; Valine

1995
A randomized, placebo-controlled comparison of oral valacyclovir and acyclovir in immunocompetent patients with recurrent genital herpes infections. The Valaciclovir International Study Group.
    Archives of dermatology, 1998, Volume: 134, Issue:2

    Topics: Acyclovir; Administration, Oral; Adolescent; Adult; Aged; Antiviral Agents; Confidence Intervals; Double-Blind Method; Female; Herpes Genitalis; Humans; Immunocompetence; Male; Middle Aged; Pain; Placebos; Prodrugs; Proportional Hazards Models; Recurrence; Remission Induction; Self Care; Time Factors; Valacyclovir; Valine; Virus Shedding; Wound Healing

1998
Factors influencing pain outcome in herpes zoster: an observational study with valaciclovir. Valaciclovir International Zoster Assessment Group (VIZA).
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2000, Volume: 14, Issue:1

    Topics: Acyclovir; Adolescent; Adult; Antiviral Agents; Female; Herpes Zoster; Humans; Male; Middle Aged; Pain; Prognosis; Treatment Outcome; Valacyclovir; Valine

2000
Comparison of the efficacy and safety of valaciclovir and acyclovir for the treatment of herpes zoster ophthalmicus.
    Ophthalmology, 2000, Volume: 107, Issue:8

    Topics: Acyclovir; Administration, Oral; Antiviral Agents; Conjunctivitis, Viral; Double-Blind Method; Female; Herpes Zoster Ophthalmicus; Humans; Immunocompetence; Keratitis; Male; Middle Aged; Pain; Safety; Tablets; Uveitis; Valacyclovir; Valine

2000
[Valaciclovir in the treatment of initial infection by genital herpes virus: comparative study].
    Enfermedades infecciosas y microbiologia clinica, 2001, Volume: 19, Issue:1

    Topics: Acyclovir; Administration, Oral; Adolescent; Adult; Antiviral Agents; Drug Administration Schedule; Female; Herpes Genitalis; Humans; Pain; Paresthesia; Patient Acceptance of Health Care; Treatment Outcome; Valacyclovir; Valine

2001

Other Studies

36 other study(ies) available for valine and Pain

ArticleYear
Variations of isovaline structure related to activity in the formalin foot assay in mice.
    Amino acids, 2017, Volume: 49, Issue:7

    Topics: Analgesics; Animals; Disease Models, Animal; Female; Formaldehyde; Mice; Pain; Valine

2017
Remote optogenetic activation and sensitization of pain pathways in freely moving mice.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, Nov-20, Volume: 33, Issue:47

    Topics: Afferent Pathways; Animals; Avoidance Learning; Cells, Cultured; Channelrhodopsins; Female; Ganglia, Spinal; Green Fluorescent Proteins; Hyperalgesia; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Morphine; NAV1.8 Voltage-Gated Sodium Channel; Optogenetics; Pain; Pain Threshold; Receptors, Purinergic P2X3; Sensory Receptor Cells; tau Proteins; Valine; Wakefulness

2013
Catechol-O-methyltransferase Val158Met polymorphism (rs4680) is associated with pain in multiple sclerosis.
    The journal of pain, 2013, Volume: 14, Issue:12

    Topics: Adult; Alleles; Catechol O-Methyltransferase; Female; Genetic Predisposition to Disease; Genotype; Humans; Male; Methionine; Middle Aged; Multiple Sclerosis; Pain; Pain Measurement; Polymorphism, Single Nucleotide; Risk Factors; Single-Blind Method; Valine

2013
N-methyl-D-aspartate receptor agonism and antagonism within the amygdaloid central nucleus suppresses pain affect: differential contribution of the ventrolateral periaqueductal gray.
    The journal of pain, 2014, Volume: 15, Issue:12

    Topics: Animals; Central Amygdaloid Nucleus; Dose-Response Relationship, Drug; Electroshock; Male; N-Methylaspartate; Narcotic Antagonists; Pain; Pain Perception; Peptide Fragments; Periaqueductal Gray; Proto-Oncogene Proteins c-fos; Random Allocation; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Reflex; Somatostatin; Valine; Vocalization, Animal

2014
Reducing pain in acute herpes zoster with plain occlusive dressings: a case report.
    Journal of medical case reports, 2015, Apr-25, Volume: 9

    Topics: Acyclovir; Adult; Antiviral Agents; Herpes Zoster; Humans; Male; Occlusive Dressings; Pain; Treatment Outcome; Valacyclovir; Valine

2015
The BDNF Val66Met polymorphism is associated with the functional connectivity dynamics of pain modulatory systems in primary dysmenorrhea.
    Scientific reports, 2016, Mar-24, Volume: 6

    Topics: Adult; Brain Mapping; Brain-Derived Neurotrophic Factor; Dysmenorrhea; Female; Humans; Methionine; Pain; Polymorphism, Single Nucleotide; Valine; Young Adult

2016
Lower cranial polyneuropathy in zoster sine herpete presenting with pain in the ear and throat: a case report.
    Rinsho shinkeigaku = Clinical neurology, 2016, 10-28, Volume: 56, Issue:10

    Topics: Acyclovir; Administration, Oral; Antiviral Agents; Betamethasone; Biomarkers; Cranial Nerve Diseases; DNA, Viral; Drug Therapy, Combination; Ear; Female; Herpesvirus 3, Human; Humans; Middle Aged; Pain; Pharynx; Treatment Outcome; Valacyclovir; Valine; Zoster Sine Herpete

2016
Unilateral abdominal bulge with sharp pain.
    European journal of internal medicine, 2017, Volume: 43

    Topics: Abdominal Muscles; Acyclovir; Antiviral Agents; Herpes Zoster; Humans; Immunoglobulin G; Male; Middle Aged; Pain; Paralysis; Valacyclovir; Valine

2017
Increased sensitivity to thermal pain following a single opiate dose is influenced by the COMT val(158)met polymorphism.
    PloS one, 2009, Jun-23, Volume: 4, Issue:6

    Topics: Adult; Alleles; Analgesics, Opioid; Catechol O-Methyltransferase; Female; Genotype; Hot Temperature; Humans; Male; Methionine; Pain; Pain Threshold; Pharmacogenetics; Polymorphism, Genetic; Valine

2009
Isovaline causes inhibition by increasing potassium conductance in thalamic neurons.
    Neuroscience, 2009, Dec-15, Volume: 164, Issue:3

    Topics: Action Potentials; Analgesics; Animals; Animals, Newborn; Calcium Signaling; Dose-Response Relationship, Drug; Glycine; Neural Inhibition; Neurons; Organ Culture Techniques; Pain; Patch-Clamp Techniques; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Valine; Ventral Thalamic Nuclei

2009
Analgesic properties of the novel amino acid, isovaline.
    Anesthesia and analgesia, 2010, Apr-01, Volume: 110, Issue:4

    Topics: Acute Disease; Analgesics, Non-Narcotic; Animals; beta-Alanine; Chronic Disease; Cisterna Magna; Female; Formaldehyde; Glutamic Acid; Glycine; Hypnotics and Sedatives; Injections; Injections, Intravenous; Injections, Spinal; Mice; Models, Molecular; Pain; Pain Measurement; Postural Balance; Receptors, Glutamate; Strychnine; Valine

2010
The effect of intra-locus coeruleus injection of 17beta-estradiol on inflammatory pain modulation in male rat.
    Behavioural brain research, 2010, Dec-25, Volume: 214, Issue:2

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Disease Models, Animal; Estradiol; Estrogen Antagonists; Estrogens; Formaldehyde; Fulvestrant; Inflammation; Locus Coeruleus; Male; Microinjections; Pain; Rats; Rats, Sprague-Dawley; Valine

2010
Multiple chronic pain states are associated with a common amino acid-changing allele in KCNS1.
    Brain : a journal of neurology, 2010, Volume: 133, Issue:9

    Topics: Animals; Chronic Disease; Cohort Studies; Comprehension; Computational Biology; Cross-Cultural Comparison; Disease Models, Animal; Female; Ganglia, Spinal; Gene Expression Profiling; Gene Expression Regulation; Genome-Wide Association Study; Genotype; Humans; Kv1.1 Potassium Channel; Linkage Disequilibrium; Male; Neurofilament Proteins; Neuropeptides; Oligonucleotide Array Sequence Analysis; Pain; Polymorphism, Genetic; Rats; Valine

2010
GABA(B) receptor-mediated selective peripheral analgesia by the non-proteinogenic amino acid, isovaline.
    Neuroscience, 2012, Jun-28, Volume: 213

    Topics: Analgesia; Analgesics; Animals; Arthritis, Experimental; Central Nervous System; Female; GABA Agonists; Hyperalgesia; Immunohistochemistry; Mice; Osteoarthritis; Pain; Peripheral Nervous System; Receptors, GABA-B; Valine

2012
[JSNP Excellent Presentation Award for AsCNP 2011: COMT Val 158 Met gene polymorphism influences the perception of other's pain].
    Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 2012, Volume: 32, Issue:2

    Topics: Awards and Prizes; Catechol O-Methyltransferase; Female; Genotype; Humans; Male; Methionine; Neuropsychological Tests; Pain; Pain Measurement; Polymorphism, Genetic; Valine; Young Adult

2012
The Val66Met polymorphism of the BDNF gene influences trigeminal pain-related evoked responses.
    The journal of pain, 2012, Volume: 13, Issue:9

    Topics: Adult; Analysis of Variance; Brain Mapping; Brain-Derived Neurotrophic Factor; Electric Stimulation; Electroencephalography; Evoked Potentials; Female; Humans; Male; Methionine; Pain; Polymorphism, Single Nucleotide; Sex Factors; Trigeminal Nerve; Valine; Young Adult

2012
Differential efficacy of intrathecal NMDA receptor antagonists on inflammatory mechanical and thermal hyperalgesia in rats.
    European journal of pharmacology, 2003, Jan-10, Volume: 459, Issue:1

    Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hyperalgesia; Inflammation; Injections, Spinal; Male; Motor Activity; Pain; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Treatment Outcome; Valine

2003
Epidural blood patch and acute varicella.
    Anesthesia and analgesia, 2004, Volume: 99, Issue:6

    Topics: Acute Disease; Acyclovir; Adult; Antiviral Agents; Blood Patch, Epidural; Chickenpox; Female; Headache; Humans; Magnetic Resonance Imaging; Pain; Spinal Cord; Valacyclovir; Valine

2004
The Val158Met polymorphism of the human catechol-O-methyltransferase (COMT) gene may influence morphine requirements in cancer pain patients.
    Pain, 2005, Volume: 116, Issue:1-2

    Topics: Aged; Catechol O-Methyltransferase; Dose-Response Relationship, Drug; Female; Genotype; Humans; Male; Methionine; Middle Aged; Morphine; Narcotics; Neoplasms; Pain; Pain Measurement; Pain Threshold; Pharmacogenetics; Polymorphism, Genetic; Retrospective Studies; Statistics, Nonparametric; Valine

2005
Alteration in sensitivity of ionotropic glutamate receptors and tachykinin receptors in spinal cord contribute to development and maintenance of nerve injury-evoked neuropathic pain.
    Neuroscience research, 2006, Volume: 56, Issue:1

    Topics: Alanine; Analgesics; Animals; Behavior, Animal; Benzamides; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Indoles; Isoindoles; Male; N-Methylaspartate; Pain; Pain Measurement; Piperidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Tachykinin; Sciatic Nerve; Spinal Cord; Substance P; Valine

2006
Mutation I136V alters electrophysiological properties of the Na(v)1.7 channel in a family with onset of erythromelalgia in the second decade.
    Molecular pain, 2008, Jan-02, Volume: 4

    Topics: Adolescent; Adult; Age of Onset; Amino Acid Substitution; Cell Line; Child; Erythromelalgia; Humans; Isoleucine; Kinetics; NAV1.7 Voltage-Gated Sodium Channel; Pain; Patch-Clamp Techniques; Sodium Channels; Valine

2008
Valaciclovir more effective than acyclovir in reducing pain from shingles.
    Infection control and hospital epidemiology, 1994, Volume: 15, Issue:1

    Topics: Acyclovir; Antiviral Agents; Herpes Zoster; Humans; Pain; Valacyclovir; Valine

1994
Treatment of acute herpes zoster: effect of early (< 48 h) versus late (48-72 h) therapy with acyclovir and valaciclovir on prolonged pain.
    The Journal of infectious diseases, 1998, Volume: 178 Suppl 1

    Topics: Acute Disease; Acyclovir; Adolescent; Adult; Antiviral Agents; Databases, Factual; Drug Administration Schedule; Female; Herpes Zoster; Humans; Male; Middle Aged; Pain; Randomized Controlled Trials as Topic; Valacyclovir; Valine

1998
Nociceptive and antinociceptive responses to intrathecally administered nicotinic agonists.
    Neuropharmacology, 1998, Volume: 37, Issue:12

    Topics: Alkaloids; Analgesia; Animals; Azocines; Bridged Bicyclo Compounds, Heterocyclic; Escape Reaction; Hindlimb; Hot Temperature; Injections, Spinal; Lobeline; Male; Mecamylamine; Microinjections; Nicotine; Nicotinic Agonists; Pain; Pyridines; Quinolizines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Valine; Vocalization, Animal

1998
Intrathecal co-administration of NMDA antagonist and NK-1 antagonist reduces MAC of isoflurane in rats.
    Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:7

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Anesthetics, Inhalation; Animals; Biphenyl Compounds; Catheters, Indwelling; Drug Combinations; Excitatory Amino Acid Antagonists; Injections, Spinal; Isoflurane; Locomotion; Male; Neurokinin-1 Receptor Antagonists; Nociceptors; Pain; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Substance P; Synaptic Transmission; Valine

1999
Intrathecal administration of an NMDA or a non-NMDA receptor antagonist reduces mechanical but not thermal allodynia in a rodent model of chronic central pain after spinal cord injury.
    Brain research, 2000, Mar-17, Volume: 859, Issue:1

    Topics: Animals; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hyperalgesia; Injections, Spinal; Male; Motor Activity; Pain; Physical Stimulation; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Cord Injuries; Valine

2000
Antinociception produced by mu opioid receptor activation in the amygdala is partly dependent on activation of mu opioid and neurotensin receptors in the ventral periaqueductal gray.
    Brain research, 2000, May-19, Volume: 865, Issue:1

    Topics: Amygdala; Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Male; Naltrexone; Narcotic Antagonists; Neural Pathways; Neurons; Neurotensin; Nociceptors; Pain; Peptides; Periaqueductal Gray; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotensin; Receptors, Opioid, delta; Receptors, Opioid, mu; Time Factors; Valine

2000
The analgesic interaction between intrathecal clonidine and glutamate receptor antagonists on thermal and formalin-induced pain in rats.
    Anesthesia and analgesia, 2001, Volume: 92, Issue:3

    Topics: Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Imidazoles; Injections, Spinal; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Valine

2001
Peripheral group I metabotropic glutamate receptors modulate nociception in mice.
    Nature neuroscience, 2001, Volume: 4, Issue:4

    Topics: Animals; Chromones; Excitatory Amino Acid Antagonists; Glycine; Hindlimb; Hot Temperature; Immunohistochemistry; Inflammation; Male; Mice; Mice, Inbred C57BL; Neurons, Afferent; Pain; Pain Measurement; Pyridines; Receptors, Metabotropic Glutamate; Valine

2001
Differential contributions of NMDA and non-NMDA receptors to spinal Fos expression evoked by superficial tissue and muscle inflammation in the rat.
    Neuroscience, 2001, Volume: 106, Issue:4

    Topics: Afferent Pathways; Animals; Cell Count; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Immunohistochemistry; Inflammation; Male; Muscle, Skeletal; Nociceptors; Pain; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Skin; Synaptic Transmission; Turpentine; Valine

2001
N-methyl-D-aspartate receptors mediate responses of rat dorsal horn neurones to hindlimb ischemia.
    Brain research, 1990, Jul-02, Volume: 522, Issue:1

    Topics: Animals; Anterior Horn Cells; Hindlimb; Injections, Spinal; Ischemia; Ketamine; Male; Pain; Physical Stimulation; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Valine

1990
Is substance P a primary afferent neurotransmitter for nociceptive input? IV. 2-Amino-5-phosphonovalerate (APV) and [D-Pro2,D-Trp7,9]-substance P exert different effects on behaviors induced by intrathecal substance P, strychnine and kainic acid.
    Brain research, 1988, Jul-12, Volume: 455, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Animals; Dose-Response Relationship, Drug; Drug Interactions; Injections, Spinal; Kainic Acid; Male; Morphine; Nociceptors; Pain; Peptide Fragments; Rats; Rats, Inbred Strains; Spinal Cord; Strychnine; Substance P; Valine

1988
Excitatory transmitters, ventral root potentials and [K+]o in the isolated frog leg-spinal cord preparation.
    Neuroscience letters, 1988, Dec-19, Volume: 95, Issue:1-3

    Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; In Vitro Techniques; Kynurenic Acid; Pain; Physical Stimulation; Potassium; Rana pipiens; Spinal Nerve Roots; Substance P; Valine

1988
Intrathecal N-methyl-D-aspartate (NMDA) activates both nociceptive and antinociceptive systems.
    Brain research, 1987, Sep-29, Volume: 422, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Analgesia; Animals; Aspartic Acid; Behavior, Animal; Decerebrate State; Injections, Spinal; Male; N-Methylaspartate; Nociceptors; Pain; Rats; Valine

1987
A novel interaction between dynorphin(1-13) and an N-methyl-D-aspartate site.
    Brain research, 1988, Mar-08, Volume: 443, Issue:1-2

    Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Aspartic Acid; Atropine; Binding, Competitive; Dipeptides; Dynorphins; Hot Temperature; Kinetics; Male; N-Methylaspartate; Pain; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine

1988
The stress of a novel environment reduces formalin pain: possible role of serotonin.
    European journal of pharmacology, 1986, Jul-15, Volume: 126, Issue:1-2

    Topics: Animals; Environment; Formaldehyde; Habituation, Psychophysiologic; Methysergide; Naloxone; Pain; Rats; Serotonin; Stress, Psychological; Valine

1986