Page last updated: 2024-11-06

thyroxine and Post-Cardiac Arrest Syndrome

thyroxine has been researched along with Post-Cardiac Arrest Syndrome in 1 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Post-Cardiac Arrest Syndrome: A reperfusion syndrome characterized by various pathophysiological processes after CARDIAC ARREST. It may include post-cardiac arrest brain injury (HYPOXIA-ISCHEMIA, BRAIN), cardiocirculatory dysfunction, (e.g., systemic ISCHEMIA), HYPERGLYCEMIA; MULTIPLE ORGAN FAILURE and delayed death.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Frenette, AJ1
Williamson, D1
Williams, V1
Lagacé, AM1
Charbonney, E1
Serri, K1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of the Efficacy and Safety of Levothyroxine in Brain Death Organ Donors: a Randomized Controlled Trial[NCT02211053]Phase 415 participants (Actual)Interventional2014-07-31Terminated (stopped due to Recruitment was too slow and we cannot anticipate to recruit the target sample size)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for thyroxine and Post-Cardiac Arrest Syndrome

ArticleYear
A Pilot Randomized Controlled Trial Comparing Levothyroxine to Placebo in Neurologically Deceased Donors.
    Progress in transplantation (Aliso Viejo, Calif.), 2019, Volume: 29, Issue:3

    Topics: Adult; Brain Death; Brain Injuries, Traumatic; Double-Blind Method; Echocardiography; Feasibility St

2019
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