Page last updated: 2024-08-23

simvastatin and Pain

simvastatin has been researched along with Pain in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (13.04)18.2507
2000's10 (43.48)29.6817
2010's7 (30.43)24.3611
2020's3 (13.04)2.80

Authors

AuthorsStudies
Barbirato, DDS; Diniz, JA; do Nascimento, EHL; Dourado, ACAG; Laureano Filho, JR; Pontual, ADA1
Aggarwal, K; Dayal, S; Gowda V M, V; Kaur, R; Sharma, S1
Battaglia, M; Benincasa, G; Bignucolo, A; Comello, F; De Lucia, D; De Lucia, V; Di Francia, R; Grillo, MR; Leonardi, G; Licito, A; Marotta, G; Mentone, L1
Hoppe, C; Jacob, E; Kuypers, F; Larkin, S; Styles, L; Vichinsky, E1
Alboghobeish, S; Ghorbanzadeh, B; Mansouri, MT; Naghizadeh, B1
Cavalca, V; Dal Bo, L; Giroli, M; Nava, MC; Tremoli, E; Werba, JP1
de Carvalho, M; Evangelista, T; Ferro, J; Pereira, P1
Arnold, Ch; Hagmann, N; Lamy, O1
Barreiro-de-Acosta, M; Campos-Franco, J; Losada-Ares, L; Pérez-Pampín, E1
Chad, DA; David, WS; Hedley-Whyte, ET; Kambadakone, A1
Hisa, H; Mutoh, J; Ohsawa, M; Ono, H; Yamamoto, S1
Bruckert, E; Dallongeville, J; Rosenbaum, D; Sabouret, P1
Bannykh, S; England, JD; Gray, NL; Haas, RH; Hathaway, S; Kimura, BJ; Phillips, PS; Vladutiu, GD1
Comarow, A1
Ponte, CD; Wratchford, P1
Rogge, N1
Hiatt, WH; Linnebur, SA1
Dande, A; Holford, TR; Kocherla, M; Ruaño, G; Seip, RL; Smith, A; Sorokin, A; Thompson, PD; Windemuth, A; Wu, AH1
O'Grady, J; Schmid, P; Sinzinger, H1
Lupattelli, G; Palumbo, B; Sinzinger, H1
Desager, JP; Harvengt, C; Horsmans, Y1
England, JD; Stewart, PM; Viles, A; Walsh, JC1

Trials

4 trial(s) available for simvastatin and Pain

ArticleYear
Tomographic evaluation of the effect of simvastatin topical use on alveolar bone microarchitecture, pain and swelling after mandibular third molar extraction: a randomized controlled trial.
    Clinical oral investigations, 2022, Volume: 26, Issue:4

    Topics: Alveolar Bone Loss; Alveolar Ridge Augmentation; Edema; Humans; Molar, Third; Pain; Simvastatin; Single-Blind Method; Tooth Extraction; Tooth Socket

2022
Simvastatin reduces vaso-occlusive pain in sickle cell anaemia: a pilot efficacy trial.
    British journal of haematology, 2017, Volume: 177, Issue:4

    Topics: Adolescent; Adult; Analgesics; Anemia, Sickle Cell; Arterial Occlusive Diseases; Biomarkers; C-Reactive Protein; Child; E-Selectin; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intercellular Adhesion Molecule-1; Male; Nitric Oxide; Pain; Simvastatin; Vascular Cell Adhesion Molecule-1; Vascular Endothelial Growth Factor A; Young Adult

2017
Statin-associated myopathy with normal creatine kinase levels.
    Annals of internal medicine, 2002, Oct-01, Volume: 137, Issue:7

    Topics: Aged; Anticholesteremic Agents; Atorvastatin; Biopsy; Creatine Kinase; Double-Blind Method; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Muscular Diseases; Pain; Pyrroles; Simvastatin

2002
Effects of combined bezafibrate-simvastatin appraised in healthy subjects.
    Journal of clinical pharmacology, 1992, Volume: 32, Issue:5

    Topics: Adult; Anticholesteremic Agents; Bezafibrate; Drug Administration Schedule; Drug Therapy, Combination; Humans; Lipids; Lovastatin; Male; Muscles; Pain; Phosphatidylcholine-Sterol O-Acyltransferase; Simvastatin

1992

Other Studies

19 other study(ies) available for simvastatin and Pain

ArticleYear
Scrutinising the role of simvastatin in a patient of Pachyonychia Congenita with KRT6A gene mutation.
    The Australasian journal of dermatology, 2022, Volume: 63, Issue:2

    Topics: Adult; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kelch-Like ECH-Associated Protein 1; Keratin-6; Keratoderma, Palmoplantar; Male; Mutation; NF-E2-Related Factor 2; Pachyonychia Congenita; Pain; Simvastatin

2022
Assessment of pharmacogenomic SLCO1B1 assay for prediction of neuromuscular pain in type 2 diabetes mellitus and cardiovascular patients: preliminary results.
    European review for medical and pharmacological sciences, 2020, Volume: 24, Issue:1

    Topics: Cardiovascular Diseases; Diabetes Mellitus, Type 2; DNA; Female; Genotype; Humans; Hypoglycemic Agents; Liver-Specific Organic Anion Transporter 1; Male; Middle Aged; Pain; Pain Measurement; Pharmacogenetics; Polymorphism, Single Nucleotide; Simvastatin; Sulfonylurea Compounds

2020
Systemic and local anti-nociceptive effects of simvastatin in the rat formalin assay: Role of peroxisome proliferator-activated receptor γ and nitric oxide.
    Journal of neuroscience research, 2017, Volume: 95, Issue:9

    Topics: Animals; Formaldehyde; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Irritants; Male; Nitric Oxide; Nociception; Pain; PPAR gamma; Rats; Rats, Wistar; Simvastatin

2017
The effect of green tea on simvastatin tolerability.
    Annals of internal medicine, 2008, Aug-19, Volume: 149, Issue:4

    Topics: Anticholesteremic Agents; Herb-Drug Interactions; Humans; Male; Middle Aged; Muscle, Skeletal; Pain; Simvastatin; Tea

2008
A case of asymptomatic cytoplasmic body myopathy revealed by sinvastatin.
    Neuromuscular disorders : NMD, 2009, Volume: 19, Issue:1

    Topics: Aged; Biopsy; Creatine Kinase; Cytoplasm; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inclusion Bodies; Male; Muscle Weakness; Muscle, Skeletal; Muscular Diseases; Necrosis; Pain; Pyrimidines; Rhabdomyolysis; Rosuvastatin Calcium; Simvastatin; Sulfonamides

2009
[88 years old woman with acute muscular weakness and diffuse muscular pain: have you thought about the drugs?].
    Praxis, 2010, Dec-01, Volume: 99, Issue:24

    Topics: Aged, 80 and over; Anti-Bacterial Agents; Anticholesteremic Agents; Clarithromycin; Diagnosis, Differential; Drug Interactions; Drug Therapy, Combination; Female; Humans; Muscle Weakness; Pain; Rhabdomyolysis; Simvastatin

2010
Avascular necrosis of the knees and ulcerative colitis.
    Revista espanola de enfermedades digestivas, 2011, Volume: 103, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aspirin; Cholecalciferol; Colitis, Ulcerative; Cyclosporine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Knee Joint; Male; Mesalamine; Osteonecrosis; Pain; Platelet Aggregation Inhibitors; Radiography; Simvastatin; Vitamins

2011
Case records of the Massachusetts General Hospital. Case 7-2012. A 79-year-old man with pain and weakness in the legs.
    The New England journal of medicine, 2012, Mar-08, Volume: 366, Issue:10

    Topics: Aged; Diabetes Complications; Diagnosis, Differential; Electromyography; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ileus; Leg; Male; Muscle Weakness; Muscular Diseases; Pain; Physical Examination; Quadriceps Muscle; Radiography, Abdominal; Rhabdomyolysis; Simvastatin

2012
Effect of spinally administered simvastatin on the formalin-induced nociceptive response in mice.
    Journal of pharmacological sciences, 2012, Volume: 119, Issue:1

    Topics: Analgesics; Animals; Formaldehyde; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Injections, Spinal; Male; Mevalonic Acid; Mice; Mice, Inbred ICR; Nociception; Pain; Pain Measurement; Simvastatin; Spinal Cord

2012
Discontinuation of statin therapy due to muscular side effects: a survey in real life.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2013, Volume: 23, Issue:9

    Topics: Adult; Aged; Atorvastatin; Dose-Response Relationship, Drug; Female; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Motor Activity; Muscle Cramp; Muscle Weakness; Muscle, Skeletal; Musculoskeletal Diseases; Pain; Pyrimidines; Pyrroles; Risk Factors; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Surveys and Questionnaires; Treatment Outcome

2013
Summaries for patients. Muscle abnormalities in four patients taking statins to treat unfavorable cholesterol levels.
    Annals of internal medicine, 2002, Oct-01, Volume: 137, Issue:7

    Topics: Aged; Anticholesteremic Agents; Atorvastatin; Biopsy; Creatine Kinase; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Muscular Diseases; Pain; Pyrroles; Simvastatin

2002
Heartfelt hurt. Why statins are making some patients really sore.
    U.S. news & world report, 2002, Oct-07, Volume: 133, Issue:13

    Topics: Anticholesteremic Agents; Humans; Muscles; Pain; Simvastatin; United States

2002
High-dose simvastatin and rhabdomyolysis.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2003, Apr-01, Volume: 60, Issue:7

    Topics: Aged; Anticholesteremic Agents; Humans; Male; Muscle Weakness; Pain; Pain Management; Rhabdomyolysis; Simvastatin

2003
[Generalized muscle pain in a 67-year-old patient. Myalgia/myositis in therapy with Zocor].
    Praxis, 2003, May-14, Volume: 92, Issue:20

    Topics: Aged; Anticholesteremic Agents; Creatine Kinase; Diagnosis, Differential; Emergencies; Female; Humans; Metabolic Syndrome; Muscular Diseases; Pain; Polymyositis; Rhabdomyolysis; Simvastatin

2003
Probable statin-induced testicular pain.
    The Annals of pharmacotherapy, 2007, Volume: 41, Issue:1

    Topics: Atorvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Pain; Pyrroles; Simvastatin; Testis

2007
Physiogenomic association of statin-related myalgia to serotonin receptors.
    Muscle & nerve, 2007, Volume: 36, Issue:3

    Topics: Aged; Aged, 80 and over; Atorvastatin; Female; Genomics; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Muscular Diseases; Pain; Polymorphism, Single Nucleotide; Pravastatin; Pyrroles; Receptors, Serotonin; Simvastatin

2007
Two different types of exercise-induced muscle pain without myopathy and CK-elevation during HMG-Co-enzyme-A-reductase inhibitor treatment.
    Atherosclerosis, 1999, Volume: 143, Issue:2

    Topics: Adolescent; Adult; Creatine Kinase; Dose-Response Relationship, Drug; Exercise; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Indoles; Lovastatin; Male; Middle Aged; Muscle Cramp; Muscle, Skeletal; Pain; Pravastatin; Prognosis; Risk Assessment; Simvastatin; Sports

1999
Statin induced myopathy does not show up in MIBI scintigraphy.
    Nuclear medicine communications, 2001, Volume: 22, Issue:5

    Topics: Adult; Anticholesteremic Agents; Atorvastatin; Breast Neoplasms; Fatty Acids, Monounsaturated; Female; Fluvastatin; Heptanoic Acids; Heterozygote; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Indoles; Lovastatin; Male; Middle Aged; Muscle, Skeletal; Muscular Diseases; Pain; Pravastatin; Pyridines; Pyrroles; Radionuclide Imaging; Radiopharmaceuticals; Simvastatin; Technetium Tc 99m Sestamibi

2001
Muscle side effects associated with simvastatin therapy.
    The Medical journal of Australia, 1990, Nov-05, Volume: 153, Issue:9

    Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Child; Female; Humans; Lovastatin; Male; Middle Aged; Mitochondria, Muscle; Muscular Diseases; Pain; Simvastatin

1990