pd 98059 has been researched along with Keloid in 4 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
Keloid: A sharply elevated, irregularly shaped, progressively enlarging scar resulting from formation of excessive amounts of collagen in the dermis during connective tissue repair. It is differentiated from a hypertrophic scar (CICATRIX, HYPERTROPHIC) in that the former does not spread to surrounding tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We conducted this experimental study to analyze the relationship between sphingosine-1-phosphate (S1P)-induced mitogen-activated protein (MAP) kinase pathways and keloid formation." | 7.91 | Association between sphingosine-1-phosphate-induced signal transduction via mitogen-activated protein kinase pathways and keloid formation. ( Chung, H; Jo, DI; Jung, SH; Kim, B; Kim, SH; Ko, HM; Lee, DH; Lee, SH; Song, YK, 2019) |
| "We conducted this experimental study to analyze the relationship between sphingosine-1-phosphate (S1P)-induced mitogen-activated protein (MAP) kinase pathways and keloid formation." | 3.91 | Association between sphingosine-1-phosphate-induced signal transduction via mitogen-activated protein kinase pathways and keloid formation. ( Chung, H; Jo, DI; Jung, SH; Kim, B; Kim, SH; Ko, HM; Lee, DH; Lee, SH; Song, YK, 2019) |
| "Keloids are benign tumors that occur only in response to injury, for which there is no effective treatment." | 1.33 | Differential transcriptional responses of keloid and normal keratinocytes to serum stimulation. ( Lim, IJ; Longaker, MT; Phan, TT; Xia, W; Yang, GP, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, Y | 1 |
| Kim, HJ | 1 |
| Woo, KJ | 1 |
| Cho, D | 1 |
| Bang, SI | 1 |
| Jung, SH | 1 |
| Song, YK | 1 |
| Chung, H | 1 |
| Ko, HM | 1 |
| Lee, SH | 1 |
| Jo, DI | 1 |
| Kim, B | 1 |
| Lee, DH | 1 |
| Kim, SH | 1 |
| Xia, W | 1 |
| Phan, TT | 1 |
| Lim, IJ | 1 |
| Longaker, MT | 1 |
| Yang, GP | 1 |
| Kuo, YR | 1 |
| Wu, WS | 1 |
| Wang, FS | 1 |
4 other studies available for pd 98059 and Keloid
| Article | Year |
|---|---|
Lipo-PGE1 suppresses collagen production in human dermal fibroblasts via the ERK/Ets-1 signaling pathway.
Topics: Alprostadil; Blotting, Western; Cell Line; Collagen; Dermatologic Agents; Dermis; Fibroblasts; Flavo | 2017 |
Association between sphingosine-1-phosphate-induced signal transduction via mitogen-activated protein kinase pathways and keloid formation.
Topics: Adult; Anilides; Anthracenes; Cell Line; Collagen Type I; Collagen Type I, alpha 1 Chain; Female; Fi | 2019 |
Differential transcriptional responses of keloid and normal keratinocytes to serum stimulation.
Topics: Adolescent; Adult; Anthracenes; Blood Proteins; Culture Media, Conditioned; Enzyme Inhibitors; Extra | 2006 |
Flashlamp pulsed-dye laser suppressed TGF-beta1 expression and proliferation in cultured keloid fibroblasts is mediated by MAPK pathway.
Topics: Anthracenes; Cell Proliferation; Cells, Cultured; Down-Regulation; Enzyme Inhibitors; Fibroblasts; F | 2007 |