melatonin has been researched along with Autism in 44 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Supplemental melatonin has shown promise in treating sleep onset insomnia in children with autism spectrum disorders (ASD)." | 9.16 | Melatonin for sleep in children with autism: a controlled trial examining dose, tolerability, and outcomes. ( Adkins, KW; Burnette, C; Fawkes, D; Goldman, SE; Malow, B; McGrew, SG; Wang, L, 2012) |
| "To determine the efficacy of melatonin on sleep problems in children with autistic spectrum disorder (ASD) and fragile X syndrome (FXS)." | 9.14 | The efficacy of melatonin for sleep problems in children with autism, fragile X syndrome, or autism and fragile X syndrome. ( Anders, TF; Bacalman, S; Diaz, R; Goodlin-Jones, BL; Hagerman, RJ; Jacquemont, S; Wirojanan, J, 2009) |
| "We describe our experience in using melatonin to treat insomnia, a common sleep concern, in children with autism spectrum disorders." | 9.13 | Melatonin for insomnia in children with autism spectrum disorders. ( Andersen, IM; Kaczmarska, J; Malow, BA; McGrew, SG, 2008) |
| "Nocturnal 6-sulphatoxymelatonin excretion rate was significantly and substantially lower in patients with autism than in normal controls (mean +/- SEM, ." | 9.11 | Nocturnal excretion of 6-sulphatoxymelatonin in children and adolescents with autistic disorder. ( Anderson, GM; Charbuy, H; Pichard, N; Tordjman, S; Touitou, Y, 2005) |
| "A novel biochemical model for autism is presented, which proposes that a subgroup of autistic individuals may have a hypersecretion of pineal melatonin that produces a cascade of biochemical effects including a corresponding hyposecretion of pituitary proopiomelanocortin (POMC) peptides and a hypersecretion of hypothalamic opioid peptides and serotonin (5-HT)." | 8.78 | A novel biochemical model linking dysfunctions in brain melatonin, proopiomelanocortin peptides, and serotonin in autism. ( Chamberlain, RS; Herman, BH, 1990) |
| "Sleep disturbances, abnormal melatonin secretion, and increased inflammation are aspects of autism spectrum disorder (ASD) pathophysiology." | 8.02 | Disrupted nocturnal melatonin in autism: Association with tumor necrosis factor and sleep disturbances. ( Anderson, G; da Silveira Cruz-Machado, S; Fadini, CC; Guissoni Campos, LM; Markus, RP; Pinato, L, 2021) |
| "Melatonin is accessed by almost one quarter of children on the autism spectrum in New Zealand, with higher observed rates among females and those aged between 5 and 11 years, of European ethnicity, and presenting with co-occurring mental health conditions." | 8.02 | Melatonin dispensing among New Zealand children aged 0-18 years with autism: a nationwide cross-sectional study. ( Bowden, N; Eggleston, MJF; McLay, LK; Schluter, PJ; Woodford, EC, 2021) |
| "Of 15 patients with disappearing effectiveness of melatonin, seven were diagnosed with autism spectrum disorder, and in four of them a SNP was found." | 7.79 | CYP1A2 polymorphisms in slow melatonin metabolisers: a possible relationship with autism spectrum disorder? ( Braam, W; Curfs, L; Didden, R; Keijzer, H; Smits, M; Struijker Boudier, H, 2013) |
| "Day and nighttime urinary excretion of 6-sulphatoxymelatonin (6-SM) was examined during a 24-h period in post-pubertal individuals with autism (N=43) and typically developing controls (N=26) matched for age, sex and pubertal stage." | 7.78 | Day and nighttime excretion of 6-sulphatoxymelatonin in adolescents and young adults with autistic disorder. ( Anderson, GM; Bellissant, E; Botbol, M; Camus, F; Charbuy, H; Cohen, D; Fougerou, C; Graignic, R; Kermarrec, S; Tordjman, S; Touitou, Y, 2012) |
| "Children with autism often suffer from sleep disturbances, and compared to age-matched controls, have decreased melatonin levels, as indicated by urine levels of the primary melatonin metabolite, 6-sulfatoxymelatonin (6-SM)." | 7.77 | Relation of melatonin to sleep architecture in children with autism. ( Beyderman, L; Botzolakis, EJ; Leu, RM; Malow, BA; Surdyka, K; Wang, L, 2011) |
| "Melatonin appears to be promising as an efficient and seemingly safe alternative for treatment of severe circadian sleep disturbances in adults with autism." | 7.75 | Melatonin in treatment of chronic sleep disorders in adults with autism: a retrospective study. ( Bertschy, G; Deriaz, N; Galli-Carminati, G, 2009) |
| "An abnormal circadian pattern of melatonin was found in a group of young adults with an extreme autism syndrome." | 7.69 | Brief report: circadian melatonin, thyroid-stimulating hormone, prolactin, and cortisol levels in serum of young adults with autism. ( Hadjez, J; Knobler, H; Lerner, Y; Meir, D; Nir, I; Zilber, N, 1995) |
| "Melatonin is an endogenous hormone and can restore gut microbial dysbiosis under various disease conditions." | 5.72 | Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism. ( Cui, Y; Li, XG; Liu, W; Liu, X; Qiu, B; Wang, X; Xiang, G; Yu, M; Zhang, D; Zhang, Y, 2022) |
| "Supplemental melatonin has shown promise in treating sleep onset insomnia in children with autism spectrum disorders (ASD)." | 5.16 | Melatonin for sleep in children with autism: a controlled trial examining dose, tolerability, and outcomes. ( Adkins, KW; Burnette, C; Fawkes, D; Goldman, SE; Malow, B; McGrew, SG; Wang, L, 2012) |
| "To determine the efficacy of melatonin on sleep problems in children with autistic spectrum disorder (ASD) and fragile X syndrome (FXS)." | 5.14 | The efficacy of melatonin for sleep problems in children with autism, fragile X syndrome, or autism and fragile X syndrome. ( Anders, TF; Bacalman, S; Diaz, R; Goodlin-Jones, BL; Hagerman, RJ; Jacquemont, S; Wirojanan, J, 2009) |
| "We describe our experience in using melatonin to treat insomnia, a common sleep concern, in children with autism spectrum disorders." | 5.13 | Melatonin for insomnia in children with autism spectrum disorders. ( Andersen, IM; Kaczmarska, J; Malow, BA; McGrew, SG, 2008) |
| "Nocturnal 6-sulphatoxymelatonin excretion rate was significantly and substantially lower in patients with autism than in normal controls (mean +/- SEM, ." | 5.11 | Nocturnal excretion of 6-sulphatoxymelatonin in children and adolescents with autistic disorder. ( Anderson, GM; Charbuy, H; Pichard, N; Tordjman, S; Touitou, Y, 2005) |
| "A novel biochemical model for autism is presented, which proposes that a subgroup of autistic individuals may have a hypersecretion of pineal melatonin that produces a cascade of biochemical effects including a corresponding hyposecretion of pituitary proopiomelanocortin (POMC) peptides and a hypersecretion of hypothalamic opioid peptides and serotonin (5-HT)." | 4.78 | A novel biochemical model linking dysfunctions in brain melatonin, proopiomelanocortin peptides, and serotonin in autism. ( Chamberlain, RS; Herman, BH, 1990) |
| "We developed methods for identifying people on the autism spectrum and defined their sleep problems using the key words, "sleep" or "melatonin", or International Classification of Diseases (ICD) codes." | 4.12 | Characterizing sleep disorders in an autism-specific collection of electronic health records. ( Davis, LK; Hucks, D; Johnston, R; Malow, BA; Maxwell-Horn, A; Niarchou, M; Singer, EV; Sutcliffe, JS, 2022) |
| "Melatonin is accessed by almost one quarter of children on the autism spectrum in New Zealand, with higher observed rates among females and those aged between 5 and 11 years, of European ethnicity, and presenting with co-occurring mental health conditions." | 4.02 | Melatonin dispensing among New Zealand children aged 0-18 years with autism: a nationwide cross-sectional study. ( Bowden, N; Eggleston, MJF; McLay, LK; Schluter, PJ; Woodford, EC, 2021) |
| "Sleep disturbances, abnormal melatonin secretion, and increased inflammation are aspects of autism spectrum disorder (ASD) pathophysiology." | 4.02 | Disrupted nocturnal melatonin in autism: Association with tumor necrosis factor and sleep disturbances. ( Anderson, G; da Silveira Cruz-Machado, S; Fadini, CC; Guissoni Campos, LM; Markus, RP; Pinato, L, 2021) |
| "To test the possible association between oxytocin and melatonin levels with the severity of social and cognitive dysfunctions, and to study the correlation between these parameters in children with autism." | 3.83 | Low oxytocin and melatonin levels and their possible role in the diagnosis and prognosis in Iraqi autistic children. ( Abdul-Rasheed, OF; Abdulamir, HA; Abdulghani, EA, 2016) |
| "Of 15 patients with disappearing effectiveness of melatonin, seven were diagnosed with autism spectrum disorder, and in four of them a SNP was found." | 3.79 | CYP1A2 polymorphisms in slow melatonin metabolisers: a possible relationship with autism spectrum disorder? ( Braam, W; Curfs, L; Didden, R; Keijzer, H; Smits, M; Struijker Boudier, H, 2013) |
| "Day and nighttime urinary excretion of 6-sulphatoxymelatonin (6-SM) was examined during a 24-h period in post-pubertal individuals with autism (N=43) and typically developing controls (N=26) matched for age, sex and pubertal stage." | 3.78 | Day and nighttime excretion of 6-sulphatoxymelatonin in adolescents and young adults with autistic disorder. ( Anderson, GM; Bellissant, E; Botbol, M; Camus, F; Charbuy, H; Cohen, D; Fougerou, C; Graignic, R; Kermarrec, S; Tordjman, S; Touitou, Y, 2012) |
| "Children with autism often suffer from sleep disturbances, and compared to age-matched controls, have decreased melatonin levels, as indicated by urine levels of the primary melatonin metabolite, 6-sulfatoxymelatonin (6-SM)." | 3.77 | Relation of melatonin to sleep architecture in children with autism. ( Beyderman, L; Botzolakis, EJ; Leu, RM; Malow, BA; Surdyka, K; Wang, L, 2011) |
| "Melatonin appears to be promising as an efficient and seemingly safe alternative for treatment of severe circadian sleep disturbances in adults with autism." | 3.75 | Melatonin in treatment of chronic sleep disorders in adults with autism: a retrospective study. ( Bertschy, G; Deriaz, N; Galli-Carminati, G, 2009) |
| "This study reports on melatonin treatment in autism." | 3.70 | Effect of melatonin on sleep-wake rhythm: the sleep diary of an autistic male. ( Hayashi, E, 2000) |
| "An abnormal circadian pattern of melatonin was found in a group of young adults with an extreme autism syndrome." | 3.69 | Brief report: circadian melatonin, thyroid-stimulating hormone, prolactin, and cortisol levels in serum of young adults with autism. ( Hadjez, J; Knobler, H; Lerner, Y; Meir, D; Nir, I; Zilber, N, 1995) |
| "People with autism spectrum disorder (ASD) commonly experience other comorbidities." | 2.66 | Sleep in autism: A biomolecular approach to aetiology and treatment. ( Baker, EK; Ballester, P; Peiró, AM; Richdale, AL, 2020) |
| "Melatonin has shown promising results in the treatment of insomnia in children with ASD." | 2.46 | Epidemiology and management of insomnia in children with autistic spectrum disorders. ( Ferri, R; Miano, S, 2010) |
| "Indeed, sleep disorders and low melatonin levels are frequently observed in ASD." | 2.44 | The possible interplay of synaptic and clock genes in autism spectrum disorders. ( Bourgeron, T, 2007) |
| "Melatonin is an endogenous hormone and can restore gut microbial dysbiosis under various disease conditions." | 1.72 | Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism. ( Cui, Y; Li, XG; Liu, W; Liu, X; Qiu, B; Wang, X; Xiang, G; Yu, M; Zhang, D; Zhang, Y, 2022) |
| "Sleep disorders (SD) are common in autism spectrum disorder (ASD), yet relatively little is known about the potential genetic mechanisms involved in SD and ASD comorbidity." | 1.56 | Brief Report: A Gene Enrichment Approach Applied to Sleep and Autism. ( Abel, EA; Mannin, OR; Marceau, K; Schwichtenberg, AJ, 2020) |
| "This paper presents a new approach to autism - a complex and still enigmatic condition." | 1.46 | Chromatographic determination of harmalans in the urine of autistic children. ( Axt, A; Jóźwik-Pruska, J; Kałużna-Czaplińska, J, 2017) |
| "Sleep problems in children with autism spectrum disorders (ASD) are under-recognized and under-treated." | 1.42 | Treatment for Sleep Problems in Children with Autism and Caregiver Spillover Effects. ( Bellando, J; Brouwer, WB; Frye, RE; Kovacs, E; Kuhlthau, KA; Payakachat, N; Pyne, JM; Tilford, JM; Williams, DK, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.27) | 18.7374 |
| 1990's | 7 (15.91) | 18.2507 |
| 2000's | 14 (31.82) | 29.6817 |
| 2010's | 12 (27.27) | 24.3611 |
| 2020's | 10 (22.73) | 2.80 |
| Authors | Studies |
|---|---|
| Tse, AC | 1 |
| Lee, PH | 1 |
| Zhang, J | 1 |
| Chan, RC | 1 |
| Ho, AW | 1 |
| Lai, EW | 1 |
| Singer, EV | 1 |
| Niarchou, M | 1 |
| Maxwell-Horn, A | 1 |
| Hucks, D | 1 |
| Johnston, R | 1 |
| Sutcliffe, JS | 1 |
| Davis, LK | 1 |
| Malow, BA | 5 |
| Liu, X | 3 |
| Cui, Y | 3 |
| Zhang, Y | 3 |
| Xiang, G | 3 |
| Yu, M | 3 |
| Wang, X | 5 |
| Qiu, B | 3 |
| Li, XG | 3 |
| Liu, W | 3 |
| Zhang, D | 3 |
| Nogueira, HA | 1 |
| de Castro, CT | 1 |
| da Silva, DCG | 1 |
| Pereira, M | 1 |
| Xu, M | 1 |
| Wang, L | 3 |
| Wang, Y | 1 |
| Deng, J | 1 |
| Wang, F | 1 |
| Pan, S | 1 |
| Zhao, Y | 1 |
| Liao, A | 1 |
| Chen, D | 1 |
| Shen, J | 1 |
| Yang, F | 1 |
| Li, Y | 1 |
| Wang, S | 1 |
| Ballester, P | 1 |
| Richdale, AL | 1 |
| Baker, EK | 1 |
| Peiró, AM | 1 |
| Yang, LL | 1 |
| Stiernborg, M | 1 |
| Skott, E | 1 |
| Söderström, Å | 1 |
| Giacobini, M | 1 |
| Lavebratt, C | 1 |
| da Silveira Cruz-Machado, S | 1 |
| Guissoni Campos, LM | 1 |
| Fadini, CC | 1 |
| Anderson, G | 1 |
| Markus, RP | 1 |
| Pinato, L | 2 |
| McLay, LK | 1 |
| Schluter, PJ | 1 |
| Eggleston, MJF | 1 |
| Woodford, EC | 1 |
| Bowden, N | 1 |
| Zuculo, GM | 1 |
| Gonçalves, BSB | 1 |
| Brittes, C | 1 |
| Menna-Barreto, L | 1 |
| Abel, EA | 1 |
| Schwichtenberg, AJ | 1 |
| Mannin, OR | 1 |
| Marceau, K | 1 |
| Tian, Y | 1 |
| Yabuki, Y | 1 |
| Moriguchi, S | 1 |
| Fukunaga, K | 1 |
| Mao, PJ | 1 |
| Hong, LJ | 1 |
| Lu, YM | 1 |
| Wang, R | 1 |
| Ahmed, MM | 1 |
| Liao, MH | 1 |
| Huang, JY | 1 |
| Zhang, RT | 1 |
| Zhou, TY | 1 |
| Long, S | 1 |
| Han, F | 1 |
| Al-Ghamdi, M | 1 |
| Al-Ayadhi, L | 1 |
| El-Ansary, A | 1 |
| Tilford, JM | 1 |
| Payakachat, N | 1 |
| Kuhlthau, KA | 1 |
| Pyne, JM | 1 |
| Kovacs, E | 1 |
| Bellando, J | 1 |
| Williams, DK | 1 |
| Brouwer, WB | 1 |
| Frye, RE | 1 |
| Abdulamir, HA | 1 |
| Abdul-Rasheed, OF | 1 |
| Abdulghani, EA | 1 |
| Kałużna-Czaplińska, J | 1 |
| Jóźwik-Pruska, J | 1 |
| Axt, A | 1 |
| Johnson, KP | 1 |
| Galli-Carminati, G | 1 |
| Deriaz, N | 1 |
| Bertschy, G | 1 |
| Mulder, EJ | 1 |
| Anderson, GM | 3 |
| Kemperman, RF | 1 |
| Oosterloo-Duinkerken, A | 1 |
| Minderaa, RB | 1 |
| Kema, IP | 1 |
| Wirojanan, J | 1 |
| Jacquemont, S | 1 |
| Diaz, R | 1 |
| Bacalman, S | 1 |
| Anders, TF | 1 |
| Hagerman, RJ | 1 |
| Goodlin-Jones, BL | 1 |
| Miano, S | 1 |
| Ferri, R | 1 |
| Leu, RM | 1 |
| Beyderman, L | 1 |
| Botzolakis, EJ | 1 |
| Surdyka, K | 1 |
| Malow, B | 1 |
| Adkins, KW | 1 |
| McGrew, SG | 2 |
| Goldman, SE | 1 |
| Fawkes, D | 1 |
| Burnette, C | 1 |
| Tordjman, S | 2 |
| Bellissant, E | 1 |
| Botbol, M | 1 |
| Charbuy, H | 2 |
| Camus, F | 1 |
| Graignic, R | 1 |
| Kermarrec, S | 1 |
| Fougerou, C | 1 |
| Cohen, D | 1 |
| Touitou, Y | 2 |
| Braam, W | 1 |
| Keijzer, H | 1 |
| Struijker Boudier, H | 1 |
| Didden, R | 1 |
| Smits, M | 1 |
| Curfs, L | 1 |
| Manning-Courtney, P | 1 |
| Brown, J | 1 |
| Molloy, CA | 1 |
| Reinhold, J | 1 |
| Murray, D | 1 |
| Sorensen-Burnworth, R | 1 |
| Messerschmidt, T | 1 |
| Kent, B | 1 |
| Pichard, N | 1 |
| Gupta, R | 1 |
| Hutchins, J | 1 |
| Chen, F | 1 |
| Lemonnier, E | 1 |
| Lazartigues, A | 1 |
| Planche, P | 1 |
| Giannotti, F | 1 |
| Cortesi, F | 1 |
| Cerquiglini, A | 1 |
| Bernabei, P | 1 |
| Garstang, J | 1 |
| Wallis, M | 1 |
| Melke, J | 1 |
| Goubran Botros, H | 1 |
| Chaste, P | 1 |
| Betancur, C | 1 |
| Nygren, G | 1 |
| Anckarsäter, H | 1 |
| Rastam, M | 1 |
| Ståhlberg, O | 1 |
| Gillberg, IC | 1 |
| Delorme, R | 1 |
| Chabane, N | 1 |
| Mouren-Simeoni, MC | 1 |
| Fauchereau, F | 1 |
| Durand, CM | 1 |
| Chevalier, F | 1 |
| Drouot, X | 1 |
| Collet, C | 1 |
| Launay, JM | 1 |
| Leboyer, M | 1 |
| Gillberg, C | 2 |
| Bourgeron, T | 2 |
| Andersen, IM | 1 |
| Kaczmarska, J | 1 |
| Zappella, M | 1 |
| Nir, I | 1 |
| Meir, D | 1 |
| Zilber, N | 1 |
| Knobler, H | 1 |
| Hadjez, J | 1 |
| Lerner, Y | 1 |
| Horrigan, JP | 1 |
| Barnhill, LJ | 1 |
| Lord, C | 1 |
| Hayashi, E | 1 |
| Modahl, C | 1 |
| Fein, D | 1 |
| Waterhouse, L | 1 |
| Newton, N | 1 |
| Chamberlain, RS | 1 |
| Herman, BH | 1 |
| Castrogiovanni, P | 1 |
| Marazziti, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Characterization of Endogenous Melatonin Profiles in Children With Autism Spectrum Disorder.[NCT00691080] | 58 participants (Actual) | Observational | 2007-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 reviews available for melatonin and Autism
| Article | Year |
|---|---|
Melatonin for sleep disorders in people with autism: Systematic review and meta-analysis.
Topics: Autism Spectrum Disorder; Autistic Disorder; Humans; Melatonin; Polysomnography; Sleep; Sleep Wake D | 2023 |
Sleep in autism: A biomolecular approach to aetiology and treatment.
Topics: Autistic Disorder; Brain; Central Nervous System Depressants; Comorbidity; gamma-Aminobutyric Acid; | 2020 |
Assessment and pharmacologic treatment of sleep disturbance in autism.
Topics: Adolescent; Autistic Disorder; Child; Comorbidity; Humans; Hypnotics and Sedatives; Melatonin; Psych | 2008 |
Epidemiology and management of insomnia in children with autistic spectrum disorders.
Topics: Age Factors; Autistic Disorder; Behavior Therapy; Child; Electroencephalography; Epilepsy; Humans; H | 2010 |
Diagnosis and treatment of autism spectrum disorders.
Topics: Adrenergic Agents; Anticonvulsants; Autistic Disorder; Child; Genetic Predisposition to Disease; Hum | 2003 |
Sleep disorders, epilepsy, and autism.
Topics: Antioxidants; Autistic Disorder; Child; Circadian Rhythm; Epilepsy; Humans; Melatonin; Polysomnograp | 2004 |
The possible interplay of synaptic and clock genes in autism spectrum disorders.
Topics: Autistic Disorder; Carrier Proteins; Cell Adhesion Molecules, Neuronal; Child; Circadian Rhythm; Fem | 2007 |
A novel biochemical model linking dysfunctions in brain melatonin, proopiomelanocortin peptides, and serotonin in autism.
Topics: Autistic Disorder; Brain; Brain Mapping; Child; Humans; Melatonin; Peptides; Pro-Opiomelanocortin; R | 1990 |
5 trials available for melatonin and Autism
| Article | Year |
|---|---|
The efficacy of melatonin for sleep problems in children with autism, fragile X syndrome, or autism and fragile X syndrome.
Topics: Adolescent; Autistic Disorder; Central Nervous System Depressants; Child; Child, Preschool; Cross-Ov | 2009 |
Melatonin for sleep in children with autism: a controlled trial examining dose, tolerability, and outcomes.
Topics: Autistic Disorder; Central Nervous System Depressants; Child; Child, Preschool; Female; Humans; Male | 2012 |
Nocturnal excretion of 6-sulphatoxymelatonin in children and adolescents with autistic disorder.
Topics: Adolescent; Analysis of Variance; Autistic Disorder; Child; Circadian Rhythm; Communication Disorder | 2005 |
Randomized controlled trial of melatonin for children with autistic spectrum disorders and sleep problems.
Topics: Adolescent; Autistic Disorder; Child; Child, Preschool; Cross-Over Studies; Double-Blind Method; Fem | 2006 |
Melatonin for insomnia in children with autism spectrum disorders.
Topics: Adolescent; Antioxidants; Autistic Disorder; Child; Child, Preschool; Drug Evaluation; Female; Human | 2008 |
31 other studies available for melatonin and Autism
| Article | Year |
|---|---|
Effects of exercise on sleep, melatonin level, and behavioral functioning in children with autism.
Topics: Autism Spectrum Disorder; Autistic Disorder; Child; Exercise; Humans; Melatonin; Sleep; Sleep Wake D | 2022 |
Characterizing sleep disorders in an autism-specific collection of electronic health records.
Topics: Adolescent; Adult; Autism Spectrum Disorder; Autistic Disorder; Child; Electronic Health Records; Hu | 2022 |
Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism.
Topics: Akkermansia; Animals; Autism Spectrum Disorder; Autistic Disorder; Dietary Supplements; Disease Mode | 2022 |
Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism.
Topics: Akkermansia; Animals; Autism Spectrum Disorder; Autistic Disorder; Dietary Supplements; Disease Mode | 2022 |
Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism.
Topics: Akkermansia; Animals; Autism Spectrum Disorder; Autistic Disorder; Dietary Supplements; Disease Mode | 2022 |
Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism.
Topics: Akkermansia; Animals; Autism Spectrum Disorder; Autistic Disorder; Dietary Supplements; Disease Mode | 2022 |
Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism.
Topics: Akkermansia; Animals; Autism Spectrum Disorder; Autistic Disorder; Dietary Supplements; Disease Mode | 2022 |
Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism.
Topics: Akkermansia; Animals; Autism Spectrum Disorder; Autistic Disorder; Dietary Supplements; Disease Mode | 2022 |
Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism.
Topics: Akkermansia; Animals; Autism Spectrum Disorder; Autistic Disorder; Dietary Supplements; Disease Mode | 2022 |
Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism.
Topics: Akkermansia; Animals; Autism Spectrum Disorder; Autistic Disorder; Dietary Supplements; Disease Mode | 2022 |
Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism.
Topics: Akkermansia; Animals; Autism Spectrum Disorder; Autistic Disorder; Dietary Supplements; Disease Mode | 2022 |
Melatonin ameliorates sleep-wake disturbances and autism-like behaviors in the Ctnnd2 knock out mouse model of autism spectrum disorders.
Topics: Animals; Autism Spectrum Disorder; Autistic Disorder; Melatonin; Mice; Mice, Knockout; Sleep; Sleep | 2023 |
Proinflammatory mediators and their associations with medication and comorbid traits in children and adults with ADHD.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Attention Deficit Disorder with Hyperactivity; Autistic Di | 2020 |
Disrupted nocturnal melatonin in autism: Association with tumor necrosis factor and sleep disturbances.
Topics: Adolescent; Autistic Disorder; Biomarkers; Case-Control Studies; Child; Child, Preschool; Circadian | 2021 |
Melatonin dispensing among New Zealand children aged 0-18 years with autism: a nationwide cross-sectional study.
Topics: Adolescent; Autism Spectrum Disorder; Autistic Disorder; Child; Child, Preschool; Cross-Sectional St | 2021 |
Melatonin and circadian rhythms in autism: Case report.
Topics: Autistic Disorder; Behavior; Child; Circadian Rhythm; Humans; Male; Melatonin; Rest; Sleep; Sleep Wa | 2017 |
Brief Report: A Gene Enrichment Approach Applied to Sleep and Autism.
Topics: Autism Spectrum Disorder; Autistic Disorder; Circadian Rhythm; Comorbidity; Databases, Genetic; Dopa | 2020 |
Melatonin reverses the decreases in hippocampal protein serine/threonine kinases observed in an animal model of autism.
Topics: Analysis of Variance; Animals; Antioxidants; Autistic Disorder; Behavior, Animal; Calcium-Calmodulin | 2014 |
Selected biomarkers as predictive tools in testing efficacy of melatonin and coenzyme Q on propionic acid - induced neurotoxicity in rodent model of autism.
Topics: Animals; Autistic Disorder; Biomarkers; Male; Melatonin; Nerve Tissue Proteins; Neuroprotective Agen | 2014 |
Treatment for Sleep Problems in Children with Autism and Caregiver Spillover Effects.
Topics: Adult; Autistic Disorder; Behavior Therapy; Caregivers; Child; Cost of Illness; Cost-Benefit Analysi | 2015 |
Low oxytocin and melatonin levels and their possible role in the diagnosis and prognosis in Iraqi autistic children.
Topics: Adolescent; Autistic Disorder; Biomarkers; Case-Control Studies; Child; Child, Preschool; Humans; Ir | 2016 |
Chromatographic determination of harmalans in the urine of autistic children.
Topics: Adolescent; Autistic Disorder; Carbolines; Child; Child, Preschool; Chromatography, High Pressure Li | 2017 |
Melatonin in treatment of chronic sleep disorders in adults with autism: a retrospective study.
Topics: Adult; Autistic Disorder; Central Nervous System Depressants; Female; Follow-Up Studies; Humans; Mal | 2009 |
Urinary excretion of 5-hydroxyindoleacetic acid, serotonin and 6-sulphatoxymelatonin in normoserotonemic and hyperserotonemic autistic individuals.
Topics: Adolescent; Age Factors; Autistic Disorder; Creatinine; Humans; Hydroxyindoleacetic Acid; Male; Mela | 2010 |
Relation of melatonin to sleep architecture in children with autism.
Topics: Autistic Disorder; Child; Child, Preschool; Female; Humans; Male; Melatonin; Polysomnography; Sleep; | 2011 |
Day and nighttime excretion of 6-sulphatoxymelatonin in adolescents and young adults with autistic disorder.
Topics: Adolescent; Autistic Disorder; Case-Control Studies; Circadian Rhythm; Female; Humans; Male; Melaton | 2012 |
CYP1A2 polymorphisms in slow melatonin metabolisers: a possible relationship with autism spectrum disorder?
Topics: Adolescent; Adult; Autistic Disorder; Child; Child Development Disorders, Pervasive; Child, Preschoo | 2013 |
Melatonin: a panacea for desperate parents? (Hype or truth).
Topics: Autistic Disorder; Child; Child, Preschool; Humans; Melatonin; Sleep Initiation and Maintenance Diso | 2005 |
Sleep problems and information processing, a "disconnection effect" in autism?
Topics: Autistic Disorder; Brain; Cognition; Cognition Disorders; Humans; Information Storage and Retrieval; | 2006 |
An open-label study of controlled-release melatonin in treatment of sleep disorders in children with autism.
Topics: Administration, Oral; Autistic Disorder; Child; Child, Preschool; Comorbidity; Cross-Sectional Studi | 2006 |
Abnormal melatonin synthesis in autism spectrum disorders.
Topics: Acetylserotonin O-Methyltransferase; Adolescent; Adult; Autistic Disorder; Case-Control Studies; Chi | 2008 |
Endogenous opioids and opiate antagonists in autism: brief review of empirical findings and implications for clinicians.
Topics: Autistic Disorder; Brain; Endorphins; Humans; Infant, Newborn; Melatonin; Naloxone; Naltrexone; Self | 1995 |
Autism and hypomelanosis of Ito in twins.
Topics: Adolescent; Autistic Disorder; Brain; Corpus Callosum; Humans; Karyotyping; Magnetic Resonance Imagi | 1993 |
Brief report: circadian melatonin, thyroid-stimulating hormone, prolactin, and cortisol levels in serum of young adults with autism.
Topics: Adolescent; Adult; Autistic Disorder; Circadian Rhythm; Humans; Hydrocortisone; Male; Melatonin; Pro | 1995 |
More on melatonin.
Topics: Adolescent; Autistic Disorder; Humans; Male; Melatonin; Nonprescription Drugs; Sleep Initiation and | 1997 |
What is melatonin? Is it a useful treatment for sleep problems in autism?
Topics: Autistic Disorder; Humans; Melatonin; Sleep Wake Disorders | 1998 |
Effect of melatonin on sleep-wake rhythm: the sleep diary of an autistic male.
Topics: Adolescent; Autistic Disorder; Circadian Rhythm; Drug Administration Schedule; Humans; Male; Melaton | 2000 |
Does oxytocin deficiency mediate social deficits in autism?
Topics: Autistic Disorder; Biomarkers; Child; Child, Preschool; Endorphins; Female; Humans; Interpersonal Re | 1992 |
ERG b-wave amplitude and brain dopaminergic activity.
Topics: Autistic Disorder; Circadian Rhythm; Dopamine; Electroretinography; Humans; Melatonin; Retina | 1989 |