Page last updated: 2024-09-03

ly 274614 and Pain

ly 274614 has been researched along with Pain in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's5 (62.50)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dykstra, LA; Fischer, BD; Henry, FE; Ward, SJ1
Balter, RE; Dykstra, LA; Fischer, BD; Henry, FE; Miller, LL; Schmidt, KT1
Allen, RM; Dykstra, LA; Granger, AL1
Grisel, JE; Mogil, JS; Nemmani, KVS; Smith-Carliss, R; Stowe, JR1
Carrigan, KA; Dykstra, LA; Fischer, BD1
Lashbrook, J; Laughlin, TM; Nichols, ML; Ossipov, M; Porreca, F; Vanderah, TW; Wilcox, GL1
Allen, RM; Dykstra, LA1
Brodsky, M; Gorman, AL; Inturrisi, CE; Zhu, H1

Other Studies

8 other study(ies) available for ly 274614 and Pain

ArticleYear
Attenuation of morphine antinociceptive tolerance by a CB(1) receptor agonist and an NMDA receptor antagonist: Interactive effects.
    Neuropharmacology, 2010, Volume: 58, Issue:2

    Topics: Analgesics; Analgesics, Opioid; Animals; Cyclohexanols; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Drug Tolerance; Excitatory Amino Acid Antagonists; Hot Temperature; Isoquinolines; Male; Mice; Mice, Inbred C57BL; Morphine; Pain; Pain Measurement; Receptor, Cannabinoid, CB1; Receptors, N-Methyl-D-Aspartate

2010
Opioid antinociception, tolerance and dependence: interactions with the N-methyl-D-aspartate system in mice.
    Behavioural pharmacology, 2011, Volume: 22, Issue:5-6

    Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Excitatory Amino Acid Antagonists; Gene Knockdown Techniques; Isoquinolines; Male; Mice; Morphine; Morphine Dependence; Pain; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu

2011
The competitive N-methyl-D-aspartate receptor antagonist (-)-6-phosphonomethyl-deca-hydroisoquinoline-3-carboxylic acid (LY235959) potentiates the antinociceptive effects of opioids that vary in efficacy at the mu-opioid receptor.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 307, Issue:2

    Topics: Animals; Drug Synergism; Isoquinolines; Levorphanol; Male; Morphine; Narcotics; Pain; Reaction Time; Receptors, Opioid, mu; Saimiri

2003
Modulation of morphine analgesia by site-specific N-methyl-D-aspartate receptor antagonists: dependence on sex, site of antagonism, morphine dose, and time.
    Pain, 2004, Volume: 109, Issue:3

    Topics: Animals; Central Nervous System; Dextromethorphan; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Isoquinolines; Male; Mice; Morphine; Pain; Phenols; Piperidines; Quinolones; Receptors, N-Methyl-D-Aspartate; Sex Characteristics; Time Factors

2004
Effects of N-methyl-D-aspartate receptor antagonists on acute morphine-induced and l-methadone-induced antinociception in mice.
    The journal of pain, 2005, Volume: 6, Issue:7

    Topics: Analgesia; Analgesics, Opioid; Animals; Central Nervous System; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Isoquinolines; Male; Methadone; Mice; Mice, Inbred C57BL; Morphine; Nociceptors; Pain; Pain Measurement; Pain Threshold; Piperidines; Pyrrolidinones; Reaction Time; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate

2005
Spinally administered dynorphin A produces long-lasting allodynia: involvement of NMDA but not opioid receptors.
    Pain, 1997, Volume: 72, Issue:1-2

    Topics: Animals; Dizocilpine Maleate; Dynorphins; Excitatory Amino Acid Antagonists; Injections, Spinal; Isoquinolines; Male; Mice; Mice, Inbred ICR; Narcotic Antagonists; Pain; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid

1997
Role of morphine maintenance dose in the development of tolerance and its attenuation by an NMDA receptor antagonist.
    Psychopharmacology, 2000, Volume: 148, Issue:1

    Topics: Animals; Dose-Response Relationship, Drug; Drug Tolerance; Excitatory Amino Acid Antagonists; Isoquinolines; Male; Morphine; Narcotics; Nociceptors; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate

2000
Region-specific changes in NMDA receptor mRNA induced by chronic morphine treatment are prevented by the co-administration of the competitive NMDA receptor antagonist LY274614.
    Brain research. Molecular brain research, 2003, Jun-10, Volume: 114, Issue:2

    Topics: Animals; Binding, Competitive; Central Nervous System; Dizocilpine Maleate; Down-Regulation; Drug Administration Schedule; Drug Interactions; Drug Tolerance; Excitatory Amino Acid Antagonists; Isoquinolines; Male; Morphine; Neurons; Pain; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger

2003