Page last updated: 2024-10-28

lidocaine and Keloid

lidocaine has been researched along with Keloid in 11 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Keloid: A sharply elevated, irregularly shaped, progressively enlarging scar resulting from formation of excessive amounts of collagen in the dermis during connective tissue repair. It is differentiated from a hypertrophic scar (CICATRIX, HYPERTROPHIC) in that the former does not spread to surrounding tissues.

Research Excerpts

ExcerptRelevanceReference
"To study the benefit of applying topical anesthetics or a 1:1 mixture of 1% lidocaine and TA at the TA injection site to alleviate pain during keloid treatment."9.24A Topical Anesthetic and Lidocaine Mixture for Pain Relief During Keloid Treatment: A Double-Blind, Randomized Controlled Trial. ( Burusapat, C; Usanakornkul, A, 2017)
"When comparing with topical lidocaine/prilocaine (EMLA) cream, a 1:1 mixture of 1% lidocaine and epinephrine significantly alleviated pain during and after the corticosteroid injection."8.31Topical Anesthetic versus Lidocaine Mixture for Pain Relief During Keloid Treatment: A Prospective, Split Study. ( Park, TH, 2023)
"Pretreatment with 60% lidocaine tape significantly reduces the pain associated with intralesional injection of TA."7.75Effect of lidocaine tape on pain during intralesional injection of triamcinolone acetonide for the treatment of keloid. ( Hyakusoku, H; Murakami, M; Tosa, M, 2009)
"To study the benefit of applying topical anesthetics or a 1:1 mixture of 1% lidocaine and TA at the TA injection site to alleviate pain during keloid treatment."5.24A Topical Anesthetic and Lidocaine Mixture for Pain Relief During Keloid Treatment: A Double-Blind, Randomized Controlled Trial. ( Burusapat, C; Usanakornkul, A, 2017)
"When comparing with topical lidocaine/prilocaine (EMLA) cream, a 1:1 mixture of 1% lidocaine and epinephrine significantly alleviated pain during and after the corticosteroid injection."4.31Topical Anesthetic versus Lidocaine Mixture for Pain Relief During Keloid Treatment: A Prospective, Split Study. ( Park, TH, 2023)
"Pretreatment with 60% lidocaine tape significantly reduces the pain associated with intralesional injection of TA."3.75Effect of lidocaine tape on pain during intralesional injection of triamcinolone acetonide for the treatment of keloid. ( Hyakusoku, H; Murakami, M; Tosa, M, 2009)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's0 (0.00)18.2507
2000's3 (27.27)29.6817
2010's3 (27.27)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Park, TH1
Cogrel, O1
Usanakornkul, A1
Burusapat, C1
Liu, W1
Wu, X1
Gao, Z1
Song, N1
Tosa, M1
Murakami, M1
Hyakusoku, H1
Mishra, S1
Azad, S1
Sacks, L1
WILSON, WW1
Fleckman, PH1
Jeffrey, JJ1
Eisen, AZ1
Singleton, MA1
Gross, CW1
Strahan, RW1
Krugman, M1

Trials

1 trial available for lidocaine and Keloid

ArticleYear
A Topical Anesthetic and Lidocaine Mixture for Pain Relief During Keloid Treatment: A Double-Blind, Randomized Controlled Trial.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2017, Volume: 43, Issue:1

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents; Do

2017

Other Studies

10 other studies available for lidocaine and Keloid

ArticleYear
Topical Anesthetic versus Lidocaine Mixture for Pain Relief During Keloid Treatment: A Prospective, Split Study.
    The Journal of craniofacial surgery, 2023, Oct-01, Volume: 34, Issue:7

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Female; Hum

2023
[Intralesional corticosteroid injections for pre-sternal keloids].
    Annales de dermatologie et de venereologie, 2015, Volume: 142, Issue:11

    Topics: Anesthetics, Local; Glucocorticoids; Humans; Injections, Intralesional; Keloid; Lidocaine; Male; Mid

2015
Remodelling of keloid tissue into normal-looking skin.
    Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 2008, Volume: 61, Issue:12

    Topics: Anesthetics, Local; Antimetabolites; Drug Administration Schedule; Drug Therapy, Combination; Female

2008
Effect of lidocaine tape on pain during intralesional injection of triamcinolone acetonide for the treatment of keloid.
    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2009, Volume: 76, Issue:1

    Topics: Administration, Cutaneous; Adult; Anesthetics, Local; Female; Humans; Injections, Intralesional; Kel

2009
Safe and less painful injection of triamcenolone acetonide into a keloid--a technique.
    Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 2010, Volume: 63, Issue:2

    Topics: Anesthetics, Local; Bupivacaine; Glucocorticoids; Humans; Injections, Intralesional; Keloid; Lidocai

2010
Painless steroid injections for hypertrophic scars and keloids.
    British journal of plastic surgery, 2002, Volume: 55, Issue:6

    Topics: Anesthesia, Local; Anesthetics, Local; Bupivacaine; Cicatrix, Hypertrophic; Humans; Injections, Intr

2002
PROPHYLAXIS AGAINST POSTSURGICAL KELOIDS: RESULTS IN 500 PATIENTS.
    Southern medical journal, 1965, Volume: 58

    Topics: Dexamethasone; Drug Therapy; Humans; Keloid; Lidocaine; Postoperative Complications

1965
A sensitive microassay for prolyl hydroxylase: activity in normal and psoriatic skin.
    The Journal of investigative dermatology, 1973, Volume: 60, Issue:1

    Topics: Animals; Ascorbic Acid; Catalase; Chick Embryo; Collagen; Dithiothreitol; Humans; Iron; Keloid; Keto

1973
Management of keloids by surgical excision and local injections of a steroid.
    Southern medical journal, 1971, Volume: 64, Issue:11

    Topics: Adolescent; Adult; Child; Epinephrine; Female; Humans; Injections, Subcutaneous; Keloid; Lidocaine;

1971
Current concepts in the management of keloids.
    Otolaryngologic clinics of North America, 1972, Volume: 5, Issue:3

    Topics: Age Factors; Humans; Injections, Jet; Keloid; Lidocaine; Racial Groups; Sex Factors; Triamcinolone

1972