ketorolac has been researched along with Myopia in 6 studies
Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.
Myopia: A refractive error in which rays of light entering the EYE parallel to the optic axis are brought to a focus in front of the RETINA when accommodation (ACCOMMODATION, OCULAR) is relaxed. This results from an overly curved CORNEA or from the eyeball being too long from front to back. It is also called nearsightedness.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ketorolac does not improve consecutive hyperopia after LASIK for myopia and compound myopic astigmatism when compared with a matched control group." | 3.72 | Ketorolac for the regression of myopic LASIK overcorrection. ( Hayes, BC; Kaufman, SC; Shaikh, NM, 2004) |
| "The postoperative pain was evaluated using a verbal numerical rating scale." | 3.30 | Effectiveness of ketorolac-soaked bandage contact lens for pain management after photorefractive keratectomy. ( Kadioglu, E; Ucar, F, 2023) |
| "Postoperative pain was compared using the validated Wong-Baker pain scale." | 2.90 | Pain management after photorefractive keratectomy. ( D'Souza, S; Dalal, R; Khamar, P; Nair, AP; Shetty, R; Vaishnav, R, 2019) |
| "The patients were asked to score the postoperative pain in each eye with a visual analog scale at 6, 18, 24, 36, 48, 72, and 96 hours." | 2.79 | Comparison of analgesic effect of preoperative topical diclofenac and ketorolac on postoperative pain after photorefractive keratectomy. ( Hong, JP; Im, CY; Kim, EK; Kim, TI; Nam, SM; Seo, KY; Yoon, S, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Ucar, F | 1 |
| Kadioglu, E | 1 |
| Mohammadpour, M | 1 |
| Heidari, Z | 1 |
| Molani, R | 1 |
| Shetty, R | 1 |
| Dalal, R | 1 |
| Nair, AP | 1 |
| Khamar, P | 1 |
| D'Souza, S | 1 |
| Vaishnav, R | 1 |
| Hong, JP | 1 |
| Nam, SM | 1 |
| Im, CY | 1 |
| Yoon, S | 1 |
| Kim, TI | 1 |
| Kim, EK | 1 |
| Seo, KY | 1 |
| Shaikh, NM | 1 |
| Hayes, BC | 1 |
| Kaufman, SC | 1 |
| Frangouli, A | 1 |
| Shah, S | 1 |
| Chatterjee, A | 1 |
| Morgan, PB | 1 |
| Kinsey, J | 1 |
5 trials available for ketorolac and Myopia
| Article | Year |
|---|---|
Effectiveness of ketorolac-soaked bandage contact lens for pain management after photorefractive keratectomy.
Topics: Bandages; Contact Lenses, Hydrophilic; Cornea; Humans; Ketorolac; Myopia; Pain Management; Pain, Pos | 2023 |
Comparison Between Diclofenac and Ketorolac Ophthalmic Drops for Pain Management After Photorefractive Keratectomy: A Randomized Clinical Study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Female; Humans; Ket | 2019 |
Pain management after photorefractive keratectomy.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Bandages, Hydrocolloid; Contact Lenses, Hydrophilic; Female | 2019 |
Comparison of analgesic effect of preoperative topical diclofenac and ketorolac on postoperative pain after photorefractive keratectomy.
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents, Non-Steroidal; Corneal Stroma; Diclofenac; | 2014 |
Efficacy of topical nonsteroidal drops as pain relief after excimer laser photorefractive keratectomy.
Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Astigmatism; Cornea; Double-Blind | 1998 |
1 other study available for ketorolac and Myopia
| Article | Year |
|---|---|
Ketorolac for the regression of myopic LASIK overcorrection.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Astigmatism; Cornea; Corneal Topography; Humans; Hyp | 2004 |