Page last updated: 2024-10-29

ketamine and Cough

ketamine has been researched along with Cough in 15 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.

Research Excerpts

ExcerptRelevanceReference
"To determine the effects of low-dose ketamine and propofol on cough during emergence and the recovery period when administered at emergence in children undergoing fiberoptic bronchoscopy for bronchoalveolar lavage (FOBL) with sevoflurane-remifentanil anesthesia."9.22Effects of low-dose propofol vs ketamine on emergence cough in children undergoing flexible bronchoscopy with sevoflurane-remifentanil anesthesia: a randomized, double-blind, placebo-controlled trial. ( Acıkel, A; Çevıkkalp, E; Ozturk, T; Topçu, I; Yılmaz, O; Yuksel, H, 2016)
"Adding epidural or IV racemic ketamine to TEA after thoracotomy did not lead to any reduction in PPP or allodynia."9.19Perioperative epidural or intravenous ketamine does not improve the effectiveness of thoracic epidural analgesia for acute and chronic pain after thoracotomy. ( Gomar, C; Rios, J; Tena, B, 2014)
"This study was designed to investigate whether a priming dose of ketamine-dexmedetomidine can effectively suppress fentanyl-induced coughing (FIC)."9.19A priming dose of intravenous ketamine-dexmedetomidine suppresses fentanyl-induced coughing: a double-blind, randomized, controlled study. ( Hadi, SM; Ouyang, W; Saleh, AJ; Zhang, L, 2014)
"05% betamethasone gel over the Endotracheal tubes in decreasing postoperative sore throat."9.16Comparison between betamethasone gel applied over endotracheal tube and ketamine gargle for attenuating postoperative sore throat, cough and hoarseness of voice. ( Kamal, SM; Shaaban, AR, 2012)
"To evaluate the effect of low-dose ketamine on fentanyl-induced cough."9.12Premedication with intravenous low-dose ketamine suppresses fentanyl-induced cough. ( Huh, BK; J Sheen, M; Lee, MS; Lin, SL; Wong, CS; Wu, CT; Yeh, CC, 2007)
"Coughing and laryngospasm are undesirable consequences occurring when patients awaken from general anaesthesia."7.11Comparison of the effects of intravenous propofol and propofol with low-dose ketamine on preventing postextubation cough and laryngospasm among patients awakening from general anaesthesia: A prospective randomised clinical trial. ( Chungsamarnyart, Y; Munjupong, S; Pairart, J, 2022)
"To determine the effects of low-dose ketamine and propofol on cough during emergence and the recovery period when administered at emergence in children undergoing fiberoptic bronchoscopy for bronchoalveolar lavage (FOBL) with sevoflurane-remifentanil anesthesia."5.22Effects of low-dose propofol vs ketamine on emergence cough in children undergoing flexible bronchoscopy with sevoflurane-remifentanil anesthesia: a randomized, double-blind, placebo-controlled trial. ( Acıkel, A; Çevıkkalp, E; Ozturk, T; Topçu, I; Yılmaz, O; Yuksel, H, 2016)
"Adding epidural or IV racemic ketamine to TEA after thoracotomy did not lead to any reduction in PPP or allodynia."5.19Perioperative epidural or intravenous ketamine does not improve the effectiveness of thoracic epidural analgesia for acute and chronic pain after thoracotomy. ( Gomar, C; Rios, J; Tena, B, 2014)
"05% betamethasone gel over the Endotracheal tubes in decreasing postoperative sore throat."5.16Comparison between betamethasone gel applied over endotracheal tube and ketamine gargle for attenuating postoperative sore throat, cough and hoarseness of voice. ( Kamal, SM; Shaaban, AR, 2012)
"We studied the influence of memantine on experimentally induced coughing in response to citric acid and bradykinin inhalation in guinea pigs."3.78Antitussive effects of memantine in guinea pigs. ( Canning, BJ; Hilton, ECY; Saulsberry, L; Smith, JA, 2012)
"Coughing and laryngospasm are undesirable consequences occurring when patients awaken from general anaesthesia."3.11Comparison of the effects of intravenous propofol and propofol with low-dose ketamine on preventing postextubation cough and laryngospasm among patients awakening from general anaesthesia: A prospective randomised clinical trial. ( Chungsamarnyart, Y; Munjupong, S; Pairart, J, 2022)
"We report our experience of venous air embolism in three small children during placement of tunneled central venous catheters when GA was not used."1.30Air embolism during tunneled central catheter placement performed without general anesthesia in children: a potentially serious complication. ( Donaldson, JS; Morello, FP; Norman, JT; Saker, MC, 1999)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19904 (26.67)18.7374
1990's1 (6.67)18.2507
2000's3 (20.00)29.6817
2010's5 (33.33)24.3611
2020's2 (13.33)2.80

Authors

AuthorsStudies
Chungsamarnyart, Y1
Pairart, J1
Munjupong, S1
Chow, TG1
McConnell, J1
Lee, MJ1
Tena, B1
Gomar, C1
Rios, J1
Saleh, AJ1
Zhang, L1
Hadi, SM1
Ouyang, W1
Ozturk, T1
Acıkel, A1
Yılmaz, O1
Topçu, I1
Çevıkkalp, E1
Yuksel, H1
Smith, JA1
Hilton, ECY1
Saulsberry, L1
Canning, BJ1
Shaaban, AR1
Kamal, SM1
Betemariam, K1
Suzuki, M1
Kinoshita, T1
Kikutani, T1
Yokoyama, K1
Inagi, T1
Sugimoto, K1
Haraguchi, S1
Hisayoshi, T1
Shimada, Y1
Yeh, CC1
Wu, CT1
Huh, BK1
Lee, MS1
Lin, SL1
J Sheen, M1
Wong, CS1
Morello, FP1
Donaldson, JS1
Saker, MC1
Norman, JT1
Lanning, CF1
Harmel, MH1
Bryant, WM1
Coppel, DL1
Dundee, JW1
Kramer, RJ1
Roper, AL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Is The Pre-Emptive Administration Of Ketamine A Significant Adjunction To Intravenous Morphine Analgesia For Controlling Post-Operative Pain? A Randomized, Double Blind, Placebo Controlled Clinical Trial.[NCT03415191]75 participants (Actual)Interventional2012-01-05Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for ketamine and Cough

ArticleYear
Ketamine anesthesia.
    Annual review of medicine, 1975, Volume: 26

    Topics: Anesthesia, General; Animals; Blood Pressure; Bronchial Spasm; Central Nervous System; Central Venou

1975

Trials

7 trials available for ketamine and Cough

ArticleYear
Comparison of the effects of intravenous propofol and propofol with low-dose ketamine on preventing postextubation cough and laryngospasm among patients awakening from general anaesthesia: A prospective randomised clinical trial.
    Journal of perioperative practice, 2022, Volume: 32, Issue:3

    Topics: Anesthesia, General; Anesthetics, Intravenous; Cough; Humans; Ketamine; Laryngismus; Propofol; Prosp

2022
Perioperative epidural or intravenous ketamine does not improve the effectiveness of thoracic epidural analgesia for acute and chronic pain after thoracotomy.
    The Clinical journal of pain, 2014, Volume: 30, Issue:6

    Topics: Acute Disease; Administration, Intravenous; Adult; Analgesia, Epidural; Analgesics; Chronic Pain; Co

2014
A priming dose of intravenous ketamine-dexmedetomidine suppresses fentanyl-induced coughing: a double-blind, randomized, controlled study.
    Upsala journal of medical sciences, 2014, Volume: 119, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Cough; Dexmedetomidine; Double-Blind Method; Female; F

2014
Effects of low-dose propofol vs ketamine on emergence cough in children undergoing flexible bronchoscopy with sevoflurane-remifentanil anesthesia: a randomized, double-blind, placebo-controlled trial.
    Journal of clinical anesthesia, 2016, Volume: 35

    Topics: Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous;

2016
Comparison between betamethasone gel applied over endotracheal tube and ketamine gargle for attenuating postoperative sore throat, cough and hoarseness of voice.
    Middle East journal of anaesthesiology, 2012, Volume: 21, Issue:4

    Topics: Adult; Anesthesia, General; Betamethasone; Cough; Elective Surgical Procedures; Female; Gels; Glucoc

2012
Determining the plasma concentration of ketamine that enhances epidural bupivacaine-and-morphine-induced analgesia.
    Anesthesia and analgesia, 2005, Volume: 101, Issue:3

    Topics: Adult; Aged; Analgesics, Opioid; Anesthesia, Epidural; Anesthetics, Dissociative; Anesthetics, Local

2005
Premedication with intravenous low-dose ketamine suppresses fentanyl-induced cough.
    Journal of clinical anesthesia, 2007, Volume: 19, Issue:1

    Topics: Adult; Anesthesia, General; Anesthetics, Dissociative; Anesthetics, Intravenous; Cough; Double-Blind

2007

Other Studies

7 other studies available for ketamine and Cough

ArticleYear
A 2-year-old girl with periprocedural anaphylaxis.
    Allergy and asthma proceedings, 2021, 01-23, Volume: 42, Issue:1

    Topics: Allergens; Analgesics; Anaphylaxis; Child, Preschool; Cough; Cyanosis; Diagnosis, Differential; Drug

2021
Antitussive effects of memantine in guinea pigs.
    Chest, 2012, Volume: 141, Issue:4

    Topics: Animals; Antitussive Agents; Baclofen; Bradykinin; Citric Acid; Cough; Dextromethorphan; Guinea Pigs

2012
Experience in the use of laryngeal mask airway in Tikur Anbessa Hospital.
    Ethiopian medical journal, 2002, Volume: 40, Issue:3

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Dissociative; An

2002
Air embolism during tunneled central catheter placement performed without general anesthesia in children: a potentially serious complication.
    Journal of vascular and interventional radiology : JVIR, 1999, Volume: 10, Issue:6

    Topics: Anesthetics, Dissociative; Anesthetics, Intravenous; Catheterization, Central Venous; Catheters, Ind

1999
Ketamine anesthesia and intranasal or intraoral operations. A potentially dangerous combination.
    Plastic and reconstructive surgery, 1973, Volume: 51, Issue:5

    Topics: Adolescent; Adult; Aged; Airway Obstruction; Anesthesia, Intravenous; Carcinoma, Squamous Cell; Coug

1973
Ketamine anaesthesia for cardiac catheterisation.
    Anaesthesia, 1972, Volume: 27, Issue:1

    Topics: Acid-Base Equilibrium; Anesthesia, General; Anesthetics; Apnea; Atropine; Blood Pressure; Carbon Dio

1972
Ketamine anesthesia in minor otologic procedures.
    The Laryngoscope, 1971, Volume: 81, Issue:9

    Topics: Adolescent; Anesthesia, General; Anesthesia, Inhalation; Anesthetics; Blood Pressure; Child; Child,

1971