huperzine a and Pain
huperzine a has been researched along with Pain in 2 studies
huperzine A: RN given refers to 5R-(5alpha,9beta,11E)-isomer; structure given in first source
huperzine A : A sesquiterpene alkaloid isolated from a club moss Huperzia serrata that has been shown to exhibit neuroprotective activity. It is also an effective inhibitor of acetylcholinesterase and has attracted interest as a therapeutic candidate for Alzheimer's disease.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Huperzine A (HupA) is an alkaloid isolated from the Chinese club moss Huperzia serrata and has been used for improving memory, cognitive and behavioral function in patients with Alzheimer's disease in China." | 1.36 | Intrathecal huperzine A increases thermal escape latency and decreases flinching behavior in the formalin test in rats. ( Park, P; Schachter, S; Yaksh, T, 2010) |
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Park, P | 1 |
| Schachter, S | 1 |
| Yaksh, T | 1 |
| Yu, D | 1 |
| Thakor, DK | 1 |
| Han, I | 1 |
| Ropper, AE | 1 |
| Haragopal, H | 1 |
| Sidman, RL | 1 |
| Zafonte, R | 1 |
| Schachter, SC | 1 |
| Teng, YD | 1 |
Other Studies
2 other studies available for huperzine a and Pain
| Article | Year |
|---|---|
Intrathecal huperzine A increases thermal escape latency and decreases flinching behavior in the formalin test in rats.
Topics: Alkaloids; Analgesics; Animals; Atropine; Behavior, Animal; Catheterization; Dose-Response Relations | 2010 |
Alleviation of chronic pain following rat spinal cord compression injury with multimodal actions of huperzine A.
Topics: Alkaloids; Animals; Behavior, Animal; Female; Pain; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Spin | 2013 |