Page last updated: 2024-10-21

huperzine a and Pain

huperzine a has been researched along with Pain in 2 studies

huperzine A: RN given refers to 5R-(5alpha,9beta,11E)-isomer; structure given in first source
huperzine A : A sesquiterpene alkaloid isolated from a club moss Huperzia serrata that has been shown to exhibit neuroprotective activity. It is also an effective inhibitor of acetylcholinesterase and has attracted interest as a therapeutic candidate for Alzheimer's disease.

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"Huperzine A (HupA) is an alkaloid isolated from the Chinese club moss Huperzia serrata and has been used for improving memory, cognitive and behavioral function in patients with Alzheimer's disease in China."1.36Intrathecal huperzine A increases thermal escape latency and decreases flinching behavior in the formalin test in rats. ( Park, P; Schachter, S; Yaksh, T, 2010)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Park, P1
Schachter, S1
Yaksh, T1
Yu, D1
Thakor, DK1
Han, I1
Ropper, AE1
Haragopal, H1
Sidman, RL1
Zafonte, R1
Schachter, SC1
Teng, YD1

Other Studies

2 other studies available for huperzine a and Pain

ArticleYear
Intrathecal huperzine A increases thermal escape latency and decreases flinching behavior in the formalin test in rats.
    Neuroscience letters, 2010, Feb-05, Volume: 470, Issue:1

    Topics: Alkaloids; Analgesics; Animals; Atropine; Behavior, Animal; Catheterization; Dose-Response Relations

2010
Alleviation of chronic pain following rat spinal cord compression injury with multimodal actions of huperzine A.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Feb-19, Volume: 110, Issue:8

    Topics: Alkaloids; Animals; Behavior, Animal; Female; Pain; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Spin

2013