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furosemide and Gout

furosemide has been researched along with Gout in 24 studies

Furosemide: A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.
furosemide : A chlorobenzoic acid that is 4-chlorobenzoic acid substituted by a (furan-2-ylmethyl)amino and a sulfamoyl group at position 2 and 5 respectively. It is a diuretic used in the treatment of congestive heart failure.

Gout: Metabolic disorder characterized by recurrent acute arthritis, hyperuricemia and deposition of sodium urate in and around the joints, sometimes with formation of URIC ACID calculi.

Research Excerpts

ExcerptRelevanceReference
"Gout patients receiving a combination of allopurinol and furosemide require higher allopurinol doses to achieve the target serum urate (SU) of <6 mg/dl (Stamp et al."7.80Molecular mechanism of an adverse drug-drug interaction of allopurinol and furosemide in gout treatment. ( Bahn, A; Knake, C; Stamp, L, 2014)
"Twenty-three cases with gout receiving furosemide and allopurinol were recruited."5.16Furosemide increases plasma oxypurinol without lowering serum urate--a complex drug interaction: implications for clinical practice. ( Barclay, ML; Chapman, PT; Drake, J; Frampton, C; O'Donnell, JL; Stamp, LK; Zhang, M, 2012)
" The only precipitating factor to be found was the chronic and unnecessary overuse of furosemide, apparently resulting from a psychological profile of anorexia nervosa."3.69Female premenopausal tophaceous gout induced by long-term diuretic abuse. ( Chazerain, P; Delahousse, M; Hayem, G; Kahn, MF; Meyer, O; Palazzo, E, 1996)
"Forty-nine patients with gout, many with hypertension and/or renal calculi, were given hydrochlorothiazide, furosemide, or ticrynafen."3.66Effects of diuretics on urate and calcium excretion. ( Berger, L; Kaung, C; Sarkozi, L; Yü, T, 1981)
"Dark red nodules that drained an opaque amber liquid developed on the extensor surfaces of both legs in a 69-year-old woman receiving furosemide and spironolactone for congestive heart failure."3.65Panniculitis of the legs with urate crystal deposition. ( Niemi, KM, 1977)
"Treatment of gout has two goals: Treatment of the acute gout attack, to terminate pain and disability and treatment of hyperuricemia by lifestyle modification and with urate lowering drugs."1.42[Hyperuricemia and gout]. ( Gröbner, W, 2015)
"Furthermore, congestive heart failure is associated with impaired creatinine clearance and increased urea and urate, and osteoporosis and hip fractures are characterized by low albumin and cholesterol."1.32Association of biochemical values with morbidity in the elderly: a population-based Swedish study of persons aged 82 or more years. ( Berg, S; Evrin, PE; Johansson, B; McClearn, G; Nilsson, SE; Takkinen, S; Tryding, N, 2003)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199016 (66.67)18.7374
1990's2 (8.33)18.2507
2000's2 (8.33)29.6817
2010's4 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Knake, C1
Stamp, L1
Bahn, A1
Gröbner, W1
Jutabha, P1
Anzai, N1
Kitamura, K1
Taniguchi, A1
Kaneko, S1
Yan, K1
Yamada, H1
Shimada, H1
Kimura, T1
Katada, T1
Fukutomi, T1
Tomita, K1
Urano, W1
Yamanaka, H1
Seki, G1
Fujita, T1
Moriyama, Y1
Yamada, A1
Uchida, S1
Wempe, MF1
Endou, H1
Sakurai, H1
Stamp, LK1
Barclay, ML1
O'Donnell, JL1
Zhang, M1
Drake, J1
Frampton, C1
Chapman, PT1
Nilsson, SE1
Takkinen, S1
Tryding, N1
Evrin, PE1
Berg, S1
McClearn, G1
Johansson, B1
Bufalari, A1
Meloni, G1
Williamson, PJ1
Ene, MD1
Roberts, CJ1
Poe, TE1
Scott, RB1
Keith, JF1
Yü, T1
Berger, L1
Sarkozi, L1
Kaung, C1
Hayem, G1
Delahousse, M1
Meyer, O1
Palazzo, E1
Chazerain, P1
Kahn, MF1
Perez-Ruiz, F1
Alonso-Ruiz, A1
Calabozo, M1
Duruelo, J1
Chopra, KF1
Grossman, ME1
Takala, J1
von Essen, R1
Isomämki, H1
Niemi, KM1
Ermolenko, VM1
Balkarov, IM1
Rozhdestvenskaia, TM1
Wordsworth, BP1
Mowat, AG1
Dimitriu, CG1
Nestor, R1
Oh, MS1
Carroll, HJ1
Clemmons, JE1
Vagnucci, AH1
Levison, SP1
Whang, ES1
Ravera, M1
Spaziante, B1
Lovisato, L1
Maieron, PL1
Rastogi, SP1
Volans, G1
Elliott, RW1
Eccleston, DW1
Ashcroft, R1
Webster, D1
Kerr, DN1
McSherry, J1
Humphreys, DM1

Trials

1 trial available for furosemide and Gout

ArticleYear
Furosemide increases plasma oxypurinol without lowering serum urate--a complex drug interaction: implications for clinical practice.
    Rheumatology (Oxford, England), 2012, Volume: 51, Issue:9

    Topics: Adult; Aged; Allopurinol; Area Under Curve; Case-Control Studies; Diuretics; Drug Interactions; Drug

2012

Other Studies

23 other studies available for furosemide and Gout

ArticleYear
Molecular mechanism of an adverse drug-drug interaction of allopurinol and furosemide in gout treatment.
    Biochemical and biophysical research communications, 2014, Sep-12, Volume: 452, Issue:1

    Topics: Allopurinol; Cell Line; Drug Interactions; Furosemide; Gout; Humans

2014
[Hyperuricemia and gout].
    Deutsche medizinische Wochenschrift (1946), 2015, Volume: 140, Issue:21

    Topics: Allopurinol; Arthritis, Gouty; Colchicine; Diagnosis, Differential; Drug Therapy, Combination; Furos

2015
Human sodium phosphate transporter 4 (hNPT4/SLC17A3) as a common renal secretory pathway for drugs and urate.
    The Journal of biological chemistry, 2010, Nov-05, Volume: 285, Issue:45

    Topics: Animals; Bumetanide; Diuretics; Furosemide; Genetic Predisposition to Disease; Glucose Transport Pro

2010
Association of biochemical values with morbidity in the elderly: a population-based Swedish study of persons aged 82 or more years.
    Scandinavian journal of clinical and laboratory investigation, 2003, Volume: 63, Issue:7-8

    Topics: Aged; Aged, 80 and over; Biomarkers; Blood Chemical Analysis; Body Mass Index; Cholesterol; Creatine

2003
Evaluation of a new oral diuretic agent. Furosemide (Lasix).
    JAMA, 1967, Jun-12, Volume: 200, Issue:11

    Topics: Diuresis; Edema; Furosemide; Gout; Humans; Water-Electrolyte Balance

1967
[The behavior of uricemia during treatment with spironolactone and with other diuretics].
    Minerva medica, 1967, Nov-07, Volume: 58, Issue:89

    Topics: Acetazolamide; Adolescent; Adult; Aged; Chlorthalidone; Clopamide; Diuretics; Ethacrynic Acid; Femal

1967
A study of the potential interactions between azapropazone and frusemide in man.
    British journal of clinical pharmacology, 1984, Volume: 18, Issue:4

    Topics: Adult; Apazone; Drug Interactions; Female; Furosemide; Gout; Humans; Male; Potassium; Sodium; Triazi

1984
Interaction of indomethacin with furosemide.
    The Journal of family practice, 1983, Volume: 16, Issue:3

    Topics: Aged; Arthritis; Drug Interactions; Female; Furosemide; Gout; Heart Failure; Humans; Indomethacin; W

1983
Effects of diuretics on urate and calcium excretion.
    Archives of internal medicine, 1981, Volume: 141, Issue:7

    Topics: Adult; Aged; Calcium; Chlorides; Furosemide; Glycolates; Gout; Humans; Hydrochlorothiazide; Middle A

1981
Female premenopausal tophaceous gout induced by long-term diuretic abuse.
    The Journal of rheumatology, 1996, Volume: 23, Issue:12

    Topics: Adult; Anorexia Nervosa; Diuretics; Female; Furosemide; Gout; Humans; Premenopause; Substance-Relate

1996
Treatment of gout after transplantation.
    British journal of rheumatology, 1998, Volume: 37, Issue:5

    Topics: Allopurinol; Azathioprine; Cyclosporine; Diuretics; Drug Interactions; Furosemide; Gout; Gout Suppre

1998
Images in clinical medicine. Finger-pad tophi.
    The New England journal of medicine, 2002, May-30, Volume: 346, Issue:22

    Topics: Cyclosporine; Diuretics; Elbow; Fingers; Furosemide; Gout; Humans; Immunosuppressive Agents; Lung Tr

2002
[Unusual reaction to diuretics].
    Duodecim; laaketieteellinen aikakauskirja, 1978, Volume: 94, Issue:11

    Topics: Aged; Female; Furosemide; Gout; Humans

1978
Panniculitis of the legs with urate crystal deposition.
    Archives of dermatology, 1977, Volume: 113, Issue:5

    Topics: Aged; Arthritis; Diagnosis, Differential; Female; Furosemide; Gout; Heart Failure; Humans; Lipase; S

1977
[Case of secondary podagra associated with long-term administration of diuretics].
    Klinicheskaia meditsina, 1985, Volume: 63, Issue:2

    Topics: Adult; Benzothiadiazines; Diuretics; Female; Furosemide; Gout; Humans; Self Medication; Sodium Chlor

1985
Rapid development of gouty tophi after diuretic therapy.
    The Journal of rheumatology, 1985, Volume: 12, Issue:2

    Topics: Aged; Diuretics; Female; Furosemide; Gout; Heart Failure; Humans; Uric Acid

1985
[Progress in the field of rheumatic and collagen diseases].
    Medicina interna, 1972, Volume: 24, Issue:7

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Collagen Diseases; Furosem

1972
A mechanism for hyporeninemic hypoaldosteronism in chronic renal disease.
    Metabolism: clinical and experimental, 1974, Volume: 23, Issue:12

    Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Aldosterone; Blood Pressure; Circadian Rhythm; D

1974
[Hyperuricemia due to diuretics].
    Minerva medica, 1973, Jan-20, Volume: 64, Issue:4

    Topics: Acetazolamide; Aged; Chlorothiazide; Chlorthalidone; Diuretics; Ethacrynic Acid; Furosemide; Gout; H

1973
[Secondary gout caused by drugs].
    Minerva medica, 1971, Feb-24, Volume: 62, Issue:16

    Topics: Aged; Anemia; Furosemide; Gout; Heart Failure; Humans; Male; Middle Aged; Transfusion Reaction

1971
High dose frusemide in the treatment of hypertension in chronic renal insufficiency and of terminal renal failure.
    Postgraduate medical journal, 1971, Volume: 47

    Topics: Adolescent; Adult; Creatine; Creatinine; Diuresis; Female; Furosemide; Gout; Humans; Hypertension, R

1971
Acute gout complicating frusemide therapy.
    The Practitioner, 1968, Volume: 201, Issue:205

    Topics: Aged; Furosemide; Gout; Humans; Male

1968
Acute gout apparently precipitated by furosemide.
    British medical journal, 1966, Apr-23, Volume: 1, Issue:5494

    Topics: Blood; Diuretics; Furosemide; Gout; Humans; Male; Middle Aged; Pulmonary Edema; Uric Acid; Urine

1966