Page last updated: 2024-08-17

folic acid and Autism

folic acid has been researched along with Autism in 63 studies

Research

Studies (63)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (7.94)	18.7374
1990's	3 (4.76)	18.2507
2000's	9 (14.29)	29.6817
2010's	34 (53.97)	24.3611
2020's	12 (19.05)	2.80

Authors

Authors	Studies
Wu, T; Zhang, Y	1
Bjørk, MH; Gilhus, NE; Husebye, ESN; Riedel, B; Wendel, AWK	1
Mills, JL; Molloy, AM	1
Amada, N; Futamura, T; Kakumoto, Y; Maeda, K	1
Brei, T; Castillo, H; Castillo, J; Thibadeau, JK	1
Bjørk, MH; Bjørke-Monsen, AL; Gervin, K; Gilhus, NE; Nilsen Husebye, ES; Riedel, B; Romanowska, J; Selmer, K	1
Zablow, SB	1
Hirokawa, K; Honjo, K; Ikehara, S; Iso, H; Kimura, T; Sato, T; Ueda, K	1
Donhauser, J	1
Konkel, L	1
Cheng, Q; Di, Y; Fan, J; Kang, M; Lan, J; Li, J; Li, Z; Ren, W; Tian, Y; Wei, C; Zhai, C; Zheng, Q	1
Bakulski, KM; Baylin, A; Brieger, KK; Croen, LA; Dou, JF; Fallin, MD; Feinberg, JI; Hertz-Picciotto, I; Newschaffer, CJ; Pearce, CL; Schmidt, RJ	1
Bilbo, S; Gentry, L; Herbert, MR; Holzknecht, ZE; Hornik, CD; Lin, SS; Nevison, CD; Parker, W; Rao, R	1
Meador, KJ	1
Bjørk, M; Daltveit, AK; Gilhus, NE; Kolstad, E; Riedel, B; Spigset, O; Veiby, G	1
Fluegge, K	1
Cheng, J; Cordero, JF; Eskenazi, B; Hendren, RL; Widjaja, F	1
Cao, Y; Li, L; Li, Q; Sun, C; Wu, H; Wu, L; Xia, W; Zhang, Q; Zou, M	1
Albertini, DF	1
Kałużna-Czaplińska, J; Michalska, M; Rynkowski, J; Żurawicz, E	1
Berger-Sweeney, JE; Schaevitz, LR	1
Baxter, P	1
Ghassabian, A; Jaddoe, VW; Roza, SJ; Steenweg-de Graaff, J; Tiemeier, H	1
Coşar, A; Gültepe, M; Ipçioğlu, OM; Ozcan, O	1
Barua, S; Brown, WT; Junaid, MA; Kuizon, S	1
Desai, A; Quadros, EV; Sequeira, JM	2
D'Souza, P; Farmer, C; Hyland, K; Langley, WA; Rodriguez, AN; Shoffner, J; Soskey, L; Spence, SJ; Swedo, SE; Thurm, A; Trommer, B	1
Sun, C; Wu, L; Xia, W; Zhao, D; Zou, M	1
Alrokayan, SA; Bharathi, V; Hussain, T; Krishna Prasad, C; Naik, U; Radha Rama Devi, A; Sai Shruti, P; Shaik Mohammad, N	1
Asztalos, E; Gao, Y; Moddemann, D; Sheng, C; Sun, W; Walker, M; Wen, SW; Xie, RH; Zwaigenbaum, L	1
Shoffner, J	1
Rogers, EJ	1
Leeming, RJ; Lucock, M	1
Akella, RR; Chintakindi, KP; Jain, JM; Mohammad, NS; Naik, U; Singh, RP	1
Ornoy, A	1
Currenti, SA	1
Angley, MT; Fenech, M; Main, PA; O'Doherty, CE; Thomas, P	1
Cleves, MA; Gaylor, DW; James, SJ; Jernigan, S; Lehman, S; Melnyk, S; Pavliv, O; Seidel, L; Trusty, T	1
Beaudet, AL; Goin-Kochel, RP	1
Chukoskie, L; Kamen, BA	1
Beard, CM; Katusic, SK; Panser, LA	1
Kałużna-Czaplińska, J; Michalska, M; Rynkowski, J	1
LaSalle, JM	1
Harsányi, E; Kummer, A	1
Al-Farsi, YM; Al-Sharbati, MM; Ali, A; Deth, RC; Essa, MM; Waly, MI	1
Addlagatta, A; Digumarti, RR; Divyya, S; Gottumukkala, SR; Kumar, A; Kutala, VK; Murthy, PV; Naushad, SM; Rammurti, S; Reddy, ChR	1
Al-Adawi, S; Al-Farsi, O; Al-Farsi, YM; Al-Khaduri, MM; Al-Khalili, M; Al-Shafaee, M; Al-Sharbati, MM; Ali, A; Deth, RC; Gupta, I; Hodgson, NW; Ouhtit, A; Waly, MI	1
Bacino, CA; Blau, N; Bottiglieri, T; Curry, S; del Gaudio, D; Finnell, RH; Hyland, K; Miller, G; Moretti, P; Neul, JL; Peters, S; Ramaekers, VT; Roa, B; Sahoo, T; Scaglia, F; Zhu, H	1
Maimburg, RD; Vaeth, M	1
Adams, M; Baker, K; Fardell, S; Lucock, M; Ng, X; Stuart, J	1
Bacino, CA; Bottiglieri, T; Del Gaudio, D; Goldman, D; Hopkin, RJ; Hyland, K; Min, SH; Moretti, P; Peach, E; Peters, SU; Roa, B; Sahoo, T; Scaglia, F	1
Blau, N; Nassogne, MC; Quadros, EV; Ramaekers, VT; Sequeira, JM	1
Cohen, DJ; Lowe, TL; Miller, S; Young, JG	1
Chudley, AE; Evans, JA; Samadder, P	1
Arrieta, I; Flores, P; Gil, A; Martinez, B; Nuñez, T; Usobiaga, E	1
Siva Sankar, DV	1
Bandy, MD; Butterworth, CE; Eto, I	1
George, CH; Madison, LS; Mosher, GA	1
Albertsson-Wikland, K; Gillberg, C; Johansson, R; Törnblom, M; Wahlström, J	1
Brown, WT; Cohen, IL; Dobkin, C; Fisch, G; Jenkins, EC; Krawczun, MS; Miezejeski, C; Rudelli, R; Wisniewski, K; Wolf-Schein, E	1

Reviews

15 review(s) available for folic acid and Autism

Article	Year
The role of oxidative stress, inflammation and acetaminophen exposure from birth to early childhood in the induction of autism. The Journal of international medical research, 2017, Volume: 45, Issue:2 Topics: Acetaminophen; Analgesics, Non-Narcotic; Aspartame; Autistic Disorder; Child; Child, Preschool; Female; Folic Acid; Humans; Hyperbilirubinemia; Infant; Inflammation; Male; Metals, Heavy; Organophosphates; Oxidative Stress; Pregnancy; Risk Factors; Thimerosal; Vitamin B 12	2017
Improving autism perinatal risk factors: A systematic review. Medical hypotheses, 2019, Volume: 127 Topics: Autistic Disorder; Birth Intervals; Breast Feeding; Environmental Exposure; Fatty Acids, Omega-3; Female; Folic Acid; Humans; Immune System; Male; Maternal Exposure; Parents; Postpartum Period; Pregnancy; Pregnancy Complications; Risk Factors	2019
A focus on homocysteine in autism. Acta biochimica Polonica, 2013, Volume: 60, Issue:2 Topics: Animals; Autistic Disorder; Avitaminosis; Body Fluids; Cystathionine beta-Synthase; Diet; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Life Style; Male; Methylenetetrahydrofolate Reductase (NADPH2); Vitamin B 12; Vitamin B 6	2013
Gene-environment interactions and epigenetic pathways in autism: the importance of one-carbon metabolism. ILAR journal, 2012, Volume: 53, Issue:3-4 Topics: Autistic Disorder; Carbon; Child Development Disorders, Pervasive; DNA Methylation; Epigenesis, Genetic; Folic Acid; Gene-Environment Interaction; Humans; Methylenetetrahydrofolate Reductase (NADPH2)	2012
Folate and homocysteine metabolisms and their roles in the biochemical basis of neuropsychiatry. Turkish journal of medical sciences, 2014, Volume: 44, Issue:1 Topics: Alzheimer Disease; Autistic Disorder; Biological Transport; Folic Acid; Homocysteine; Humans; Psychotic Disorders	2014
The metabolic basis for developmental disorders due to defective folate transport. Biochimie, 2016, Volume: 126 Topics: Animals; Autistic Disorder; Autoantibodies; Biological Transport, Active; Female; Folate Receptor 1; Folic Acid; Folic Acid Deficiency; Humans; Neural Tube Defects; Pregnancy	2016
Clinical utility of folate pathway genetic polymorphisms in the diagnosis of autism spectrum disorders. Psychiatric genetics, 2016, Volume: 26, Issue:6 Topics: Alleles; Autism Spectrum Disorder; Autistic Disorder; Child; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genetic Testing; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Odds Ratio; Polymorphism, Single Nucleotide; Risk Factors	2016
New Perspective on Impact of Folic Acid Supplementation during Pregnancy on Neurodevelopment/Autism in the Offspring Children - A Systematic Review. PloS one, 2016, Volume: 11, Issue:11 Topics: Autism Spectrum Disorder; Autistic Disorder; Dietary Supplements; Female; Folic Acid; Humans; Pregnancy	2016
Autism: Is there a folate connection? Journal of inherited metabolic disease, 2009, Volume: 32, Issue:3 Topics: Autistic Disorder; Folic Acid; Humans; Neural Tube Defects	2009
Valproic acid in pregnancy: how much are we endangering the embryo and fetus? Reproductive toxicology (Elmsford, N.Y.), 2009, Volume: 28, Issue:1 Topics: Abnormalities, Drug-Induced; Adolescent; Animals; Anticonvulsants; Autistic Disorder; Child; Child Development; Child, Preschool; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Female; Fetus; Folic Acid; Humans; Infant; Maternal-Fetal Exchange; Milk, Human; Nervous System Diseases; Neural Tube Defects; Placenta; Pregnancy; Prenatal Exposure Delayed Effects; Risk Assessment; Semen; Syndrome; Teratogens; Valproic Acid	2009
Understanding and determining the etiology of autism. Cellular and molecular neurobiology, 2010, Volume: 30, Issue:2 Topics: Animals; Autistic Disorder; Calcitriol; Female; Folic Acid; Humans; Immune System; Metals, Heavy; Methyl-CpG-Binding Protein 2; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidation-Reduction; Pregnancy; Risk Factors	2010
Folate and methionine metabolism in autism: a systematic review. The American journal of clinical nutrition, 2010, Volume: 91, Issue:6 Topics: Autistic Disorder; Folic Acid; Humans; Methionine	2010
A genomic point-of-view on environmental factors influencing the human brain methylome. Epigenetics, 2011, Volume: 6, Issue:7 Topics: Autistic Disorder; Brain; DNA Copy Number Variations; DNA Methylation; Environmental Exposure; Epigenesis, Genetic; Folic Acid; Genome, Human; Genomics; Humans	2011
Fragile-X syndrome: diagnosis and research. Journal of pediatric psychology, 1986, Volume: 11, Issue:1 Topics: Autistic Disorder; Child Behavior Disorders; Facial Expression; Female; Folic Acid; Fragile X Syndrome; Genetic Techniques; Heterozygote; Humans; Intelligence; Language; Male; Sex Chromosome Aberrations; Testis	1986
The fragile X syndrome. Annals of the New York Academy of Sciences, 1986, Volume: 477 Topics: Autistic Disorder; Female; Folic Acid; Fragile X Syndrome; Genetic Carrier Screening; Humans; Male; Models, Genetic; Mutation; Pedigree; Sex Chromosome Aberrations	1986

Trials

2 trial(s) available for folic acid and Autism

Article	Year
Efficacy of Folic Acid Supplementation in Autistic Children Participating in Structured Teaching: An Open-Label Trial. Nutrients, 2016, Jun-07, Volume: 8, Issue:6 Topics: Autistic Disorder; Case-Control Studies; Child; Child, Preschool; Dietary Supplements; Female; Folic Acid; Humans; Male; Teaching	2016
Folic acid as an adjunct in the treatment of children with the autism fragile-X syndrome (AFRAX). Developmental medicine and child neurology, 1986, Volume: 28, Issue:5 Topics: Adolescent; Autistic Disorder; Child; Clinical Trials as Topic; Double-Blind Method; Folic Acid; Fragile X Syndrome; Humans; Male; Sex Chromosome Aberrations	1986

Other Studies

46 other study(ies) available for folic acid and Autism

Article	Year
[Relationship between serum folic acid and 25(OH)D levels and intelligence and core symptoms in children with autism]. Wei sheng yan jiu = Journal of hygiene research, 2021, Volume: 50, Issue:6 Topics: Autistic Disorder; Child; Child, Preschool; Folic Acid; Humans; Intelligence; Vitamin D	2021
Plasma unmetabolized folic acid in pregnancy and risk of autistic traits and language impairment in antiseizure medication-exposed children of women with epilepsy. The American journal of clinical nutrition, 2022, 05-01, Volume: 115, Issue:5 Topics: Autistic Disorder; Child; Child, Preschool; Cohort Studies; Epilepsy; Female; Folic Acid; Humans; Language Development Disorders; Male; Pregnancy	2022
Lowering the risk of autism spectrum disorder with folic acid: can there be too much of a good thing? The American journal of clinical nutrition, 2022, 05-01, Volume: 115, Issue:5 Topics: Autism Spectrum Disorder; Autistic Disorder; Child; Epilepsy; Female; Folic Acid; Humans; Language Development Disorders; Pregnancy	2022
Prenatal methotrexate injection increases behaviors possibly associated with depression and/or autism in rat offspring; A new animal model for mental disorder, based on folate metabolism deficit during pregnancy. Neuropsychopharmacology reports, 2022, Volume: 42, Issue:3 Topics: Animals; Autistic Disorder; Behavior, Animal; Depression; Disease Models, Animal; DNA; Female; Folic Acid; Humans; Mental Disorders; Methotrexate; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Vitamins	2022
From autism to zoom®: Spina bifida advocacy, care, education, and research in a changing word. Journal of pediatric rehabilitation medicine, 2022, Volume: 15, Issue:4 Topics: Autism Spectrum Disorder; Autistic Disorder; Child; Folic Acid; Humans; Infant; Neural Tube Defects; Prevalence; Spinal Dysraphism	2022
Correlation between 5-HT, Hcy and the incidence and severity of autism in children. Cellular and molecular biology (Noisy-le-Grand, France), 2023, Jan-31, Volume: 69, Issue:1 Topics: Autistic Disorder; Cesarean Section; Child; Female; Folic Acid; Humans; Incidence; Pregnancy; Seizures, Febrile; Serotonin; Vitamin B 12	2023
Does maternal genetic liability to folate deficiency influence the risk of antiseizure medication-associated language impairment and autistic traits in children of women with epilepsy? The American journal of clinical nutrition, 2023, Volume: 118, Issue:1 Topics: Autistic Disorder; Child; Cohort Studies; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Humans; Language Development Disorders; Pregnancy; Prenatal Exposure Delayed Effects	2023
Folate Deficiency Based Autism as an Orofacial Clefts/Neural Tube Defect Spectrum Disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 2019, Volume: 58, Issue:11 Topics: Autistic Disorder; Child; Cleft Lip; Cleft Palate; Folic Acid; Humans; Neural Tube Defects; Neurodevelopmental Disorders	2019
Associations Between Broader Autism Phenotype and Dietary Intake: A Cross-Sectional Study (Japan Environment & Children's Study). Journal of autism and developmental disorders, 2020, Volume: 50, Issue:8 Topics: Adult; Animals; Autistic Disorder; Child; Cohort Studies; Cross-Sectional Studies; Diet; Fatty Acids, Omega-3; Female; Folic Acid; Humans; Japan; Mothers; Phenotype; Pregnancy; Vitamin D; Vitamins	2020
Hormonal contraceptives and autism epidemics. Medical hypotheses, 2020, Volume: 141 Topics: Autism Spectrum Disorder; Autistic Disorder; Contraceptive Agents; Epidemics; Folic Acid; Humans	2020
Phthalates and Autistic Traits: Exploring the Association between Prenatal Exposures and Child Behavior. Environmental health perspectives, 2020, Volume: 128, Issue:10 Topics: Autistic Disorder; Canada; Child; Child Behavior; Female; Folic Acid; Humans; Pregnancy; Prenatal Exposure Delayed Effects	2020
Maternal folic acid supplementation prevents autistic behaviors in a rat model induced by prenatal exposure to valproic acid. Food & function, 2021, May-21, Volume: 12, Issue:10 Topics: Animals; Autism Spectrum Disorder; Autistic Disorder; Behavior, Animal; Dietary Supplements; Disease Models, Animal; Female; Folic Acid; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Social Behavior; Valproic Acid	2021
The Association of Prenatal Vitamins and Folic Acid Supplement Intake with Odds of Autism Spectrum Disorder in a High-Risk Sibling Cohort, the Early Autism Risk Longitudinal Investigation (EARLI). Journal of autism and developmental disorders, 2022, Volume: 52, Issue:6 Topics: Autism Spectrum Disorder; Autistic Disorder; Child; Child, Preschool; Female; Folic Acid; Humans; Pregnancy; Siblings; Vitamins	2022
Periconceptional Folate Supplementation and the Risk of Autism Following Antiepileptic Drug Exposure. JAMA neurology, 2018, 02-01, Volume: 75, Issue:2 Topics: Anticonvulsants; Autistic Disorder; Child; Dietary Supplements; Female; Folic Acid; Humans; Pregnancy	2018
Association of Folic Acid Supplementation During Pregnancy With the Risk of Autistic Traits in Children Exposed to Antiepileptic Drugs In Utero. JAMA neurology, 2018, 02-01, Volume: 75, Issue:2 Topics: Adult; Anticonvulsants; Autistic Disorder; Child, Preschool; Cohort Studies; Dietary Supplements; Epilepsy; Female; Folic Acid; Gestational Age; Humans; Infant; Logistic Models; Male; Norway; Outcome Assessment, Health Care; Pregnancy; Prenatal Exposure Delayed Effects; Surveys and Questionnaires; Vitamin B Complex	2018
Re: Folate status and autism spectrum disorders. Paediatric and perinatal epidemiology, 2018, Volume: 32, Issue:3 Topics: Autism Spectrum Disorder; Autistic Disorder; Folic Acid; Folic Acid Deficiency; Humans	2018
Folic acid improves abnormal behavior via mitigation of oxidative stress, inflammation, and ferroptosis in the BTBR T+ tf/J mouse model of autism. The Journal of nutritional biochemistry, 2019, Volume: 71 Topics: Animals; Autistic Disorder; Behavior, Animal; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Ferroptosis; Folic Acid; Hippocampus; Inflammation; Male; Memory; Methylenetetrahydrofolate Reductase (NADPH2); Mice, Inbred C57BL; Oxidative Stress; Social Behavior	2019
Periconceptual folate and autism. BMJ (Clinical research ed.), 2013, Feb-13, Volume: 346 Topics: Adult; Autistic Disorder; Child; Female; Folic Acid; Humans; Norway; Pregnancy	2013
Folate forever--all methyl group donations welcome! Journal of assisted reproduction and genetics, 2013, Volume: 30, Issue:5 Topics: Autistic Disorder; Child; Female; Folic Acid; Humans; Incidence; Infant, Newborn; Male; Methane; Preconception Care; Pregnancy; Prenatal Care; Reproductive Medicine; Reproductive Techniques, Assisted	2013
Valproate and folic acid in pregnancy: associations with autism. Developmental medicine and child neurology, 2014, Volume: 56, Issue:7 Topics: Autistic Disorder; Epilepsy; Female; Folic Acid; Humans; Pregnancy; Prenatal Exposure Delayed Effects; Valproic Acid	2014
Folate concentrations during pregnancy and autistic traits in the offspring. The Generation R Study. European journal of public health, 2015, Volume: 25, Issue:3 Topics: Autistic Disorder; Child; Dietary Supplements; Female; Folic Acid; Humans; Male; Mothers; Netherlands; Pregnancy; Prenatal Care; Prospective Studies	2015
High Gestational Folic Acid Supplementation Alters Expression of Imprinted and Candidate Autism Susceptibility Genes in a sex-Specific Manner in Mouse Offspring. Journal of molecular neuroscience : MN, 2016, Volume: 58, Issue:2 Topics: Animals; Autistic Disorder; Cerebral Cortex; Dietary Supplements; DNA Methylation; Female; Folic Acid; Genetic Predisposition to Disease; Genomic Imprinting; Male; Mice; Mice, Inbred C57BL; Pregnancy; Prenatal Exposure Delayed Effects; Prenatal Nutritional Physiological Phenomena; Sex Factors; Vitamin B Complex	2016
CSF concentrations of 5-methyltetrahydrofolate in a cohort of young children with autism. Neurology, 2016, 06-14, Volume: 86, Issue:24 Topics: Autistic Disorder; Biomarkers; Child; Child, Preschool; Folic Acid; Follow-Up Studies; Humans; Longitudinal Studies; Neuropsychological Tests; Severity of Illness Index; Tetrahydrofolates	2016
Prevention of behavioral deficits in rats exposed to folate receptor antibodies: implication in autism. Molecular psychiatry, 2017, Volume: 22, Issue:9 Topics: Animals; Antibodies; Autistic Disorder; Autoantibodies; Child; Cognition Disorders; Dexamethasone; Female; Folate Receptor 1; Folic Acid; Humans; Leucovorin; Male; Pregnancy; Rats; Rats, Long-Evans	2017
Author response: CSF concentrations of 5-methyltetrahydrofolate in a cohort of young children with autism. Neurology, 2017, 01-03, Volume: 88, Issue:1 Topics: Autistic Disorder; Child; Cohort Studies; Folic Acid; Humans; Tetrahydrofolates	2017
Has enhanced folate status during pregnancy altered natural selection and possibly Autism prevalence? A closer look at a possible link. Medical hypotheses, 2008, Volume: 71, Issue:3 Topics: Autistic Disorder; Female; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube Defects; Polymorphism, Genetic; Pregnancy; Selection, Genetic	2008
Aberrations in folate metabolic pathway and altered susceptibility to autism. Psychiatric genetics, 2009, Volume: 19, Issue:4 Topics: Alleles; Autistic Disorder; Case-Control Studies; Child; Child, Preschool; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Humans; Male; Metabolic Networks and Pathways; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide	2009
A functional polymorphism in the reduced folate carrier gene and DNA hypomethylation in mothers of children with autism. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2010, Volume: 153B, Issue:6 Topics: Adult; Alleles; Autistic Disorder; Case-Control Studies; Child; Child, Preschool; DNA Methylation; Epigenomics; Female; Folic Acid; Gene Frequency; Humans; Male; Mothers; Polymorphism, Genetic; Reduced Folate Carrier Protein; Young Adult	2010
Some, but not complete, reassurance on the safety of folic acid fortification. The American journal of clinical nutrition, 2010, Volume: 92, Issue:6 Topics: Autistic Disorder; Consumer Product Safety; Dietary Supplements; Folic Acid; Humans; Neural Tube Defects; United States	2010
Autism Speaks: meeting on folate metabolism and Autism spectrum disorders, March 19-20, 2009, Washington, DC. Journal of pediatric hematology/oncology, 2011, Volume: 33, Issue:3 Topics: Autistic Disorder; Biological Transport; Brain; Cognition Disorders; District of Columbia; Folic Acid; Genomic Instability; Humans; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, N-Methyl-D-Aspartate; Vitamin B 12	2011
Is excess folic acid supplementation a risk factor for autism? Medical hypotheses, 2011, Volume: 77, Issue:1 Topics: Autistic Disorder; Dietary Supplements; Folic Acid; Humans; Risk Factors	2011
Vitamin supplementation reduces the level of homocysteine in the urine of autistic children. Nutrition research (New York, N.Y.), 2011, Volume: 31, Issue:4 Topics: Autistic Disorder; Child; Child, Preschool; Creatinine; Dietary Supplements; Female; Folic Acid; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Male; Vitamin B 12; Vitamin B 6	2011
Comments on "Vitamin supplementation reduces the level of homocysteine in the urine of autistic children". Nutrition research (New York, N.Y.), 2011, Volume: 31, Issue:11 Topics: Autistic Disorder; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Vitamin B 12; Vitamin B 6	2011
Hyperhomocysteinemia among Omani autistic children: a case-control study. Acta biochimica Polonica, 2011, Volume: 58, Issue:4 Topics: Autistic Disorder; Biomarkers; Case-Control Studies; Child, Preschool; Fasting; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Reference Values; Vitamin B 12	2011
Paradoxical role of C1561T glutamate carboxypeptidase II (GCPII) genetic polymorphism in altering disease susceptibility. Gene, 2012, Apr-15, Volume: 497, Issue:2 Topics: Abortion, Spontaneous; Antigens, Surface; Autistic Disorder; Breast Neoplasms; Cohort Studies; Coronary Artery Disease; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Glutamate Carboxypeptidase II; Humans; Male; Polymorphism, Genetic; Prostatic Neoplasms	2012
Low folate and vitamin B12 nourishment is common in Omani children with newly diagnosed autism. Nutrition (Burbank, Los Angeles County, Calif.), 2013, Volume: 29, Issue:3 Topics: Autistic Disorder; Case-Control Studies; Child, Preschool; Diet; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Nutrition Assessment; Nutritional Status; Odds Ratio; Oman; Vitamin B 12; Vitamin B 12 Deficiency	2013
Cerebral folate deficiency with developmental delay, autism, and response to folinic acid. Neurology, 2005, Mar-22, Volume: 64, Issue:6 Topics: Adaptation, Physiological; Autistic Disorder; Cerebral Cortex; Child; Developmental Disabilities; Disease Progression; Female; Folic Acid; Folic Acid Deficiency; Genetic Predisposition to Disease; Humans; Intellectual Disability; Leucovorin; Mutation; Recovery of Function; Reduced Folate Carrier Protein; Seizures; Tetrahydrofolates; Transcription Factors; Treatment Outcome	2005
Do children born after assisted conception have less risk of developing infantile autism? Human reproduction (Oxford, England), 2007, Volume: 22, Issue:7 Topics: Adult; Autistic Disorder; Case-Control Studies; Denmark; Female; Folic Acid; Humans; Infant, Newborn; Infertility; Male; Odds Ratio; Pregnancy; Reproductive Techniques, Assisted; Risk; Risk Factors	2007
Preliminary evidence for involvement of the folate gene polymorphism 19bp deletion-DHFR in occurrence of autism. Neuroscience letters, 2007, Jul-05, Volume: 422, Issue:1 Topics: Adolescent; Autistic Disorder; Child; Child, Preschool; Female; Folic Acid; Gene Deletion; Gene Frequency; Genetic Variation; Genotype; Humans; Male; Polymorphism, Genetic; Psychiatric Status Rating Scales; Reverse Transcriptase Polymerase Chain Reaction; Tetrahydrofolate Dehydrogenase; Vitamin B 12	2007
Brief report: autistic symptoms, developmental regression, mental retardation, epilepsy, and dyskinesias in CNS folate deficiency. Journal of autism and developmental disorders, 2008, Volume: 38, Issue:6 Topics: Adolescent; Autistic Disorder; Brain; Child; Child, Preschool; Developmental Disabilities; Dyskinesias; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Humans; Infant; Infant, Newborn; Intellectual Disability; Male; Pregnancy; Psychomotor Disorders; Reference Values; Regression, Psychology; Tetrahydrofolates	2008
Folate receptor autoimmunity and cerebral folate deficiency in low-functioning autism with neurological deficits. Neuropediatrics, 2007, Volume: 38, Issue:6 Topics: Adolescent; Autistic Disorder; Autoantibodies; Carrier Proteins; Child; Child, Preschool; Female; Folate Receptors, GPI-Anchored; Folic Acid; Folic Acid Deficiency; Humans; Male; Nervous System Diseases; Receptors, Cell Surface; Tetrahydrofolates; Treatment Outcome	2007
Folic acid and B12 in autism and neuropsychiatric disturbances of childhood. Journal of the American Academy of Child Psychiatry, 1981,Winter, Volume: 20, Issue:1 Topics: Adolescent; Adult; Autistic Disorder; Child; Child, Preschool; Folic Acid; Homovanillic Acid; Humans; Mental Disorders; Middle Aged; Vitamin B 12	1981
Segregation analysis of rare autosomal folate sensitive fragile sites. American journal of medical genetics, 1993, Apr-15, Volume: 46, Issue:2 Topics: Autistic Disorder; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human; Female; Folic Acid; Genes, Dominant; Heterozygote; Humans; Intellectual Disability; Male; Pedigree; Sex Ratio	1993
Autosomal folate sensitive fragile sites in an autistic Basque sample. Annales de genetique, 1996, Volume: 39, Issue:2 Topics: Adolescent; Autistic Disorder; Case-Control Studies; Child; Chromosome Fragile Sites; Chromosome Fragility; Ethnicity; Female; Folic Acid; France; Humans; Male; Sex Characteristics	1996
Plasma levels of folates, riboflavin, vitamin B6, and ascorbate in severely disturbed children. Journal of autism and developmental disorders, 1979, Volume: 9, Issue:1 Topics: Adolescent; Affective Symptoms; Ascorbic Acid; Autistic Disorder; Child; Child Behavior Disorders; Child, Preschool; Folic Acid; Humans; Intellectual Disability; Male; Orthomolecular Therapy; Psychotic Disorders; Pyridoxine; Riboflavin; Schizophrenia	1979
Plasma and urinary levels of biopterin, neopterin, and related pterins and plasma levels of folate in infantile autism. Journal of autism and developmental disorders, 1992, Volume: 22, Issue:2 Topics: Adolescent; Autistic Disorder; Biopterins; Child; Female; Folic Acid; Humans; Male; Neopterin; Pterins	1992

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