Page last updated: 2024-10-27

fentanyl and Pain

fentanyl has been researched along with Pain in 1200 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"The addition of gabapentin to moderate sedation during D&E did not result in lower maximum recalled procedural pain."9.69Gabapentin as an adjunct for pain management during dilation and evacuation: A double-blind randomized controlled trial. ( Brant, AR; Floyd, S; Lotke, PS; Reeves, MF; Scott, RK; Tefera, E; Ye, PP, 2023)
"This study aimed to compare the efficacy of intravenous, intranasal fentanyl and oral sucrose in reducing the pain response during retinopathy of prematurity examinations using premature infant pain profile (PIPP) scores."9.69Effects of fentanyl and sucrose on pain in retinopathy examinations with pain scale, near-infrared spectroscopy, and ultrasonography: a randomized trial. ( Arman, D; Cömert, S; Gül, A; Kara, N; Seymen, Z, 2023)
"Analgesia, Fentanyl, Lidocaine spray, Pain, Rib fracture, Tramadol."9.69Comparison of the Analgesic Efficacy of Lidocaine Spray versus Tramadol and Fentanyl for Pain Control in Rib Fractures. ( Donmez, S; Erdem, AB; Sener, A, 2023)
"Our aim was to evaluate pain reduction provided by intranasal fentanyl (INF) compared with placebo in addition to ibuprofen."9.69Additive Value of Intranasal Fentanyl on Ibuprofen for Pain Management of Children With Moderate to Severe Headaches: A Randomized Controlled Trial. ( Bailey, B; Boutin, A; Gouin, S; Gravel, J; Lebel, D, 2023)
"To compare pain and the need for the opioid fentanyl use associated with the administration of phenylephrine 1."9.51Pain control and reduction of opioid use associated with intracameral phenylephrine1.0%-ketorolac 0.3% administered during cataract surgery. ( Donnenfeld, ED; Mychajlyszyn, A; Mychajlyszyn, D; Stein, R, 2022)
"We tested the following hypothesis: The addition of intranasal fentanyl to the standard practice of local infiltration with lidocaine would provide better pain control than lidocaine alone for adult ED patients undergoing I&D."9.51A Randomized, Placebo-Controlled Study of Intranasal Fentanyl as an Analgesic Adjunct For Incision and Drainage of Abscess. ( Baer, J; Feliciano, C; Friedman, BW; Gupta, C; Latev, A; Sharpe, S, 2022)
"This study investigates the effects of COMTval158met gene polymorphism on maternal anxiety and pain during delivery and on the analgesic and anxiety efficacy of dexmedetomidine during delivery."9.51Comparative study of the efficacy of dexmedetomidine and fentanyl on anxiety and pain of parturients with different COMTva1158met genotypes. ( Feng, YJ; Han, J; Pu, CX; Tang, LJ; Zhang, Y, 2022)
"Intranasal fentanyl seems to be a safe and effective alternative to acetaminophen with hydrocodone in reducing pain and improving hydration status in children with painful infectious mouth lesions and poor oral intake."9.51Intranasal Fentanyl to Reduce Pain and Improve Oral Intake in the Management of Children With Painful Infectious Mouth Lesions. ( Chen, JG; Cramm, K; Florez, C; Papa, L; Ramirez, J; Ruffin, TB; Salinero, E, 2022)
"To investigate if intravenous fentanyl or intravenous ketamine can provide adequate analgesia in preterm infants undergoing laser photocoagulation for retinopathy of prematurity (ROP)."9.41'NOPAIN-ROP' trial: Intravenous fentanyl and intravenous ketamine for pain relief during laser photocoagulation for retinopathy of prematurity (ROP) in preterm infants: A randomised trial. ( Agarwal, R; Chandra, P; Deorari, A; Madathil, S; Sankar, MJ; Thomas, D; Thukral, A, 2021)
"This study aimed to compare analgesic efficacy of intranasal (IN) ketamine to IN fentanyl for moderate to severe pain in children in a pediatric emergency department."9.41Analgesic Efficacy of Intranasal Ketamine Versus Intranasal Fentanyl for Moderate to Severe Pain in Children: A Prospective, Randomized, Double-Blind Study. ( Brady, J; Chitnis, SS; Drapkin, J; Fromm, C; Kriss, S; Likourezos, A; Motov, S; Pushkar, I; Quinn, K; Yasavolian, M, 2021)
"We sought to evaluate the efficacy of using a quick response (QR) code within video education to guide proper use of fentanyl transdermal patches and control pain, depression, and anxiety levels in cancer patients."9.34Video Education Reduces Pain and Anxiety Levels in Cancer Patients Who First Use Fentanyl Transdermal Patch: A Randomized Controlled Trial. ( Chen, J; Hu, X; Mao, X; Rao, Y; Xuan, Z; Yang, S; Ye, Z; Zhang, Y, 2020)
"To determine whether intranasal ketamine is noninferior to intranasal fentanyl for pain reduction in children presenting with acute extremity injuries."9.30Effect of Intranasal Ketamine vs Fentanyl on Pain Reduction for Extremity Injuries in Children: The PRIME Randomized Clinical Trial. ( Caruso, M; Florin, TA; Frey, TM; Mittiga, MR; Zhang, N; Zhang, Y, 2019)
" Propofol with opioids has been recommended for gastroscopy sedation but the effects on cough reflex suppression remain unclear."9.24Effect of propofol combined with opioids on cough reflex suppression in gastroscopy: study protocol for a double-blind randomized controlled trial. ( Cao, YZ; Lu, X; Xia, J; Xie, J; Yin, N; Yuan, J, 2017)
"The neurodevelopmental impact of fentanyl given to preterm newborns for pain control is still unknown."9.24Follow-up at the corrected age of 24 months of preterm newborns receiving continuous infusion of fentanyl for pain control during mechanical ventilation. ( Ancora, G; Faldella, G; Ferrari, F; Garetti, E; Lago, P; Merazzi, D; Pierantoni, L; Pirelli, A, 2017)
"To compare pain incidence and changes in pain scores with fentanyl versus placebo as pre-emptive treatment during turning and 30 min post-turning in mechanically ventilated critically ill patients."9.22Fentanyl as pre-emptive treatment of pain associated with turning mechanically ventilated patients: a randomized controlled feasibility study. ( Baños, JE; Castillo, A; Gich, I; Juanes-Borrego, E; Mancebo, J; Navarro, M; Nicolás-Arfelis, JM; Puntillo, K; Robleda, G; Roche-Campo, F; Rodríguez-Arias, A; Sendra, MÀ; Urrutia, G, 2016)
"To evaluate the efficacy of oral transmucosal fentanyl citrate (OTFC) in the treatment of dyspnea on exertion in patients with advanced cancer."9.20A randomized crossover clinical trial to evaluate the efficacy of oral transmucosal fentanyl citrate in the treatment of dyspnea on exertion in patients with advanced cancer. ( Bruera, E; Correas, MÁ; Moralo, MJ; Pinna, MÁ; Vargas, RM, 2015)
"To compare the effectiveness and safety of fentanyl with placebo as pre-emptive treatment for pain associated with turning in patients in intensive care units."9.20A randomized controlled trial of fentanyl in the pre-emptive treatment of pain associated with turning in patients under mechanical ventilation: research protocol. ( Baños, JE; Castillo, A; Gich, I; Juanes-Borrejo, E; Mancebo, J; Navarro, M; Robleda, G; Roche-Campo, F; Rodríguez-Arias, A; Sendra, MÀ; Urrútia, G, 2015)
"Transdermal fentanyl is an effective, convenient, and well-tolerated treatment for mucositis pain caused by chemoradiotherapy, which can improve ESCC patients' quality of life."9.20Efficacy and safety of transdermal fentanyl for the treatment of oral mucositis pain caused by chemoradiotherapy in patients with esophageal squamous cell carcinoma. ( Xing, SZ; Zhang, Y, 2015)
"Managing cancer pain often requires opioid medications, such as fentanyl, which is frequently initiated parenterally, and then converted to transdermal form."9.19Efficacy and safety of a six-hour continuous overlap method for converting intravenous to transdermal fentanyl in cancer pain. ( Bloise, R; Davis, MP; Samala, RV, 2014)
"To evaluate the pain on injection of propofol via different combinations of fentanyl, sufentanil or remifentanil in gastrointestinal endoscopy."9.19Comparing the pain of propofol via different combinations of fentanyl, sufentanil or remifentanil in gastrointestinal endoscopy. ( Bao, Y; Shi, D; Zhang, L, 2014)
"Fentanyl injection of small dose at auricular points achieves definite analgesic effect on procedural pain in dressing changes of burn wounds, superior to subcutaneous injection of fentanyl."9.19[Prevention of procedural pain in dressing changes of burn wounds by auricular injection of small-dose fentanyl]. ( Liu, B; Liu, YF; Su, XJ; Zhang, SH; Zhu, HX, 2014)
"Sublingual fentanyl proved inadequate in relieving pain during BMAB as no significant differences in the pain scores of the fentanyl and placebo patients were observed."9.17Pre-medication with sublingual fentanyl did not relieve pain associated with bone marrow aspiration and biopsy: a randomized feasibility trial. ( Ebeling, F; Kuivalainen, AM; Rosenberg, PH, 2013)
"In very preterm infants on mechanical ventilation, continuous fentanyl infusion plus open-label boluses of fentanyl does not reduce prolonged pain, but does reduce acute pain and increase side effects compared with open-label boluses of fentanyl alone."9.17Efficacy and safety of continuous infusion of fentanyl for pain control in preterm newborns on mechanical ventilation. ( Ancora, G; Faldella, G; Garetti, E; Lago, P; Mastrocola, M; Merazzi, D; Pierantoni, L; Pirelli, A, 2013)
"The study aimed to evaluate the effects of the pretreatment with lidocaine, fentanyl, and remifentanil using a venous occlusion technique in preventing pain caused by intravenous injection of rocuronium during induction of general anesthesia."9.17Comparison of three methods of preventing rocuronium induced pain on injection using venous occlusion technique: a randomized prospective double blind controlled study. ( Abu-Halaweh, NS; Abu-Halaweh, SA; Al-Hussami, MO; Al-Mustafa, M; Aloweidi, AK; Atyat, BS; Qudaisat, IY, 2013)
"Patients with bone-cancer pain, already on opioids, obtain clinically important, additional pain-control, with regular oxycodone/paracetamol dosing."9.16Efficacy of oxycodone/paracetamol for patients with bone-cancer pain: a multicenter, randomized, double-blinded, placebo-controlled trial. ( Fang, WX; Li, F; Sima, L; Wu, XM, 2012)
"The opioids buprenorphine and fentanyl significantly potentiate the effect of descending pain inhibition in healthy volunteers."9.16A double-blind, placebo-controlled study on the effect of buprenorphine and fentanyl on descending pain modulation: a human experimental study. ( Andresen, T; Arendt-Nielsen, L; Drewes, AM; Malver, LP; Mansikka, H; Oksche, A, 2012)
"This study compared the efficacy and safety of a 3-day-type transdermal fentanyl patch conversion by the rapid titration method to short-acting oral oxycodone for cancer pain."9.16[Three-day-type transdermal fentanyl patch conversion by rapid titration method with short-acting oral oxycodone for cancer pain]. ( Fujio, N; Ishikawa, N; Kameyama, M; Watanabe, H; Yamazaki, K, 2012)
"A number of transmucosal fentanyl formulations have been developed for the management of breakthrough cancer pain (BTCP)."9.16Efficacy and safety of fentanyl sublingual spray for the treatment of breakthrough cancer pain: a randomized, double-blind, placebo-controlled study. ( Bull, J; Dillaha, L; Geach, J; Parikh, N; Rauck, R; Reynolds, L; Scherlis, M; Stearns, L, 2012)
"We prospectively investigated the reduced effects of adverse events caused by sustained-release oral morphine and controlled-release oxycodone after rotating to the fentanyl patch in patients with metastatic breast cancer."9.16[A pilot study of the reduced effects of adverse events caused by oral morphine and oxycodone after rotating to fentanyl patch in patients with metastatic breast cancer]. ( Fujii, S; Ikeda, M; Koike, Y; Kubo, S; Kurebayashi, J; Mizutou, A; Nakashima, K; Nomura, T; Oota, Y; Saitou, W; Seki, M; Shiiki, S; Shimo, T; Sonoo, H; Tanaka, K; Yamamoto, Y; Yamashita, T, 2012)
"3°C cold water), nerve growth factor-induced muscle soreness and intradermal capsaicin-induced hyperalgesia and allodynia."9.15Pharmacokinetic/pharmacodynamic relationships of transdermal buprenorphine and fentanyl in experimental human pain models. ( Andresen, T; Arendt-Nielsen, L; Christrup, LL; Drewes, AM; Foster, DJ; Upton, RN, 2011)
"We recently reported that fentanyl pectin nasal spray (FPNS) provides superior pain relief from breakthrough cancer pain (BTCP) compared with immediate-release morphine sulfate (IRMS), with significant effects by five minutes and clinically meaningful pain relief from 10 minutes postdose."9.15Consistency of efficacy, patient acceptability, and nasal tolerability of fentanyl pectin nasal spray compared with immediate-release morphine sulfate in breakthrough cancer pain. ( Brooks, D; Davies, A; Elsner, F; Espinosa, J; Fallon, M; Reale, C; Sitte, T, 2011)
"The addition of 3% sevoflurane at the time of preoxygenation for 1 min along with routine use of lidocaine-tourniquet completely prevented pain upon propofol injection, whereas sevoflurane by itself provided similar analgesia to premixed lidocaine with propofol."9.15Sevoflurane to alleviate pain on propofol injection. ( Ali, MS; DeSousa, K, 2011)
"To compare the effectiveness of nitrous oxide/oxygen (N(2)O/O(2)) and fentanyl in relieving pain among patients with an isolated long bone fracture or main joint dislocation of the limbs."9.15Nitrous oxide/oxygen compared with fentanyl in reducing pain among adults with isolated extremity trauma: a randomized trial. ( Amini, A; Derakhshanfar, H; Dolatabadi, AA; Hatamabadi, H; Kariman, H; Majidi, A; Shahrami, A; Sheibani, K; Yaseri, M, 2011)
"This study assessed the long-term safety and tolerability of fentanyl buccal tablet (FBT) in opioid-tolerant patients with cancer and breakthrough pain (BTP) who were either naive to FBT or had completed 1 of 2 previous double-blind, placebo-controlled FBT studies (rollover patients)."9.14Fentanyl buccal tablet for the treatment of breakthrough pain in opioid-tolerant patients with chronic cancer pain: A long-term, open-label safety study. ( Messina, J; Weinstein, SM; Xie, F, 2009)
" However, remifentanil continuous infusion proved to offer significantly more stable pain control compared with the currently used combination fentanyl-midazolam."9.14Analgesia during abdominal aortic aneurysm endovascular repair: remifentanil vs. fentanyl-midazolam--a randomized controlled trial. ( Barbieri, A; Bonfreschi, V; Coppi, G; D'Amico, R; Giuliani, E; Malagnino, FC; Navi, A; Silingardi, R, 2009)
"This trial investigated the efficacy and long-term tolerability of intranasal fentanyl spray (INFS) 50 to 200 microg in the treatment of breakthrough pain in opioid-tolerant patients with cancer."9.14Efficacy and tolerability of intranasal fentanyl spray 50 to 200 microg for breakthrough pain in patients with cancer: a phase III, multinational, randomized, double-blind, placebo-controlled, crossover trial with a 10-month, open-label extension treatmen ( Colberg, T; Kaasa, S; Kaczmarek, Z; Kress, HG; Nolte, T; Orońska, A, 2009)
"The efficacy of intranasal fentanyl spray (INFS) was compared with that of oral transmucosal fentanyl citrate (OTFC) for the relief of cancer-related breakthrough pain (BTP) in an open-label, crossover trial."9.14A comparison of intranasal fentanyl spray with oral transmucosal fentanyl citrate for the treatment of breakthrough cancer pain: an open-label, randomised, crossover trial. ( Camba, MA; Colberg, T; Davies, A; Mercadante, S; Perkins, P; Poulain, P; Radbruch, L; Sitte, T, 2009)
"The aim of this study was to compare the efficacy of intravenous pretreatment with fentanyl 50 microg, fentanyl 100 microg, and lidocaine 40 mg, preceded by venous occlusion, for reducing pain on injection of propofol in adult Japanese surgical patients."9.14A comparison of pretreatment with fentanyl and lidocaine preceded by venous occlusion for reducing pain on injection of propofol: a prospective, randomized, double-blind, placebo-controlled study in adult Japanese surgical patients. ( Fujii, Y; Itakura, M, 2009)
"Fentanyl buccal soluble film (FBSF) has been developed as a treatment of breakthrough pain in opioid-tolerant patients with cancer."9.14Fentanyl buccal soluble film (FBSF) for breakthrough pain in patients with cancer: a randomized, double-blind, placebo-controlled study. ( Finn, AL; Gever, LN; North, J; Rauck, R; Tagarro, I, 2010)
"In this study we evaluated the efficacy and tolerability of sublingual fentanyl (SLF) for breakthrough pain (BTP) in adult opioid-tolerant cancer patients."9.14Sublingual administration of fentanyl to cancer patients is an effective treatment for breakthrough pain: results from a randomized phase II study. ( Derrick, R; Frank-Lissbrant, I; Howell, J; Kälkner, KM; Lennernäs, B; Lennernäs, H, 2010)
"This study evaluated the efficacy and safety of transdermal fentanyl in the outpatient treatment of head and neck cancer patients with pain caused by radiotherapy."9.14Transdermal fentanyl for pain caused by radiotherapy in head and neck cancer patients treated in an outpatient setting: a multicenter trial in Taiwan. ( Chang, JT; Chen, YJ; Lee, MS; Lin, CY; Lin, JC; Wang, HM, 2010)
"To determine if intranasal (IN) fentanyl is effective at decreasing pain that children feel during catheterization of VCUG when compared with sterile water."9.14Intranasal fentanyl versus placebo for pain in children during catheterization for voiding cystourethrography. ( Chung, S; Goldman, RD; Lim, R, 2010)
"kg(-1) added to bupivacaine significantly improves the quality of intraoperative analgesia and prolongs postoperative analgesia in children undergoing inguinal hernia repair with spinal anesthesia."9.14Effects of intrathecal fentanyl on quality of spinal anesthesia in children undergoing inguinal hernia repair. ( Apiliogullari, S; Duman, A; Duman, I, 2010)
"The intent of our study was to compare the effects of dexmedetomidine versus midazolam on perioperative hemodynamics, sedation, pain, satisfaction and recovery scores during colonoscopy."9.14A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation. ( Budak, ET; Dagli, G; Dere, K; Filiz, AI; Ozkan, S; Sucullu, I; Yeyen, S, 2010)
"This randomized, double-blind, crossover study assessed the efficacy and tolerability of a new rapid onset nasal fentanyl formulation (Fentanyl Pectin Nasal Spray; FPNS) for breakthrough cancer pain (BTCP)."9.14A multicenter, placebo-controlled, double-blind, multiple-crossover study of Fentanyl Pectin Nasal Spray (FPNS) in the treatment of breakthrough cancer pain. ( Burton, AW; Gabrail, N; Portenoy, RK; Taylor, D, 2010)
"To evaluate the time of onset, overall efficacy, and safety of fentanyl buccal tablet (FBT) for noncancer-related breakthrough pain (BTP) in opioid-tolerant adults over 12 weeks."9.14A novel 12-week study, with three randomized, double-blind placebo-controlled periods to evaluate fentanyl buccal tablets for the relief of breakthrough pain in opioid-tolerant patients with noncancer-related chronic pain. ( Farrar, JT; Messina, J; Portenoy, RK; Xie, F, 2010)
"We examined the efficacy and safety of a new transdermal fentanyl citrate patch (HFT-290), which was applied once daily in patients with cancer pain who were receiving a stable dose of once-every-three-day application transdermal fentanyl patch [TDF (72 hr)]."9.14[A phase II clinical study of once-a-day fentanyl citrate patch in patients with cancer pain--switching from once-every-three-days fentanyl patch to once-a-day fentanyl citrate patch]. ( Hashizume, T; Iseki, M; Iwao, Y; Kitajima, T; Masuda, Y; Matoba, M; Miyazaki, T; Namiki, A; Ogawa, S; Uchida, E, 2010)
"The aim of this study was to evaluate the effect and tolerability of low doses of transdermal (TD) fentanyl patches in opioid-naive patients with cancer pain."9.14Low doses of transdermal fentanyl in opioid-naive patients with cancer pain. ( Adile, C; Aielli, F; Ferrera, P; Ficorella, C; Mercadante, S; Porzio, G, 2010)
"The objective was to evaluate the use of a single 2 μg/kg dose of intranasal fentanyl as analgesia for painful orthopedic injuries in children presenting to a pediatric emergency department (ED)."9.14Use of intranasal fentanyl for the relief of pediatric orthopedic trauma pain. ( Adelgais, K; Nelson, D; Saunders, M, 2010)
"Omission of fentanyl did not reduce the overall incidence of postoperative nausea and vomiting, but did reduce the incidence of vomiting and/or moderate to severe nausea prior to discharge from 20% and 17% with fentanyl and fentanyl-dexamethasone, respectively, to 5% (P = 0."9.13Omitting fentanyl reduces nausea and vomiting, without increasing pain, after sevoflurane for day surgery. ( Bridgman, S; Smith, I; Walley, G, 2008)
"Fentanyl, a short-acting synthetic opioid, has a pharmacokinetic profile suited to fast relief of brief episodic pain."9.13Pharmacokinetics and pharmacodynamics of intranasal versus intravenous fentanyl in patients with pain after oral surgery. ( Christrup, L; Foster, D; Popper, L; Upton, R, 2008)
"We investigated the efficacy and safety of transdermal fentanyl for severe mucositis pain caused by chemotherapy."9.13Efficacy and safety of transdermal fentanyl for treatment of oral mucositis pain caused by chemotherapy. ( Cai, Q; Guo, Y; Huang, H; Li, Y; Lin, X; Sun, X; Xia, Z, 2008)
"We studied the effect of fentanyl pretreatment on alleviating pain during the injection of Propofol-Lipuro."9.13Fentanyl pre-treatment alleviates pain during injection of propofol-lipuro premixed with lignocaine. ( Ahmad, N; Balan, S; Zanariah, Y, 2008)
"To compare the efficacy of fentanyl and remifentanil as prodrugs in the prevention of rocuronium injection pain by using a control group."9.13Comparison of the effectiveness of pretreatment by fentanyl and remifentanil on rocuronium induced injection pain. ( Bayindir, S; Ellidokuz, H; Gunerli, A; Iyilikci, L; Sari, M, 2008)
"A novel transdermal matrix patch delivery system for fentanyl has been developed to deliver improved management of cancer pain compared with that obtained using current fentanyl reservoir patches."9.13Efficacy, safety and pharmacokinetic study of a novel fentanyl-containing matrix transdermal patch system in Japanese patients with cancer pain. ( Hanaoka, K; Hosokawa, T; Ishida, T; Kitajima, T; Mashimo, S; Miyazaki, T; Namiki, A; Nogami, S; Ogawa, S, 2008)
"The comparison of ketamine with fentanyl for pain control of pediatric orthopedic emergencies remains controversial."9.12Influence of ketamine versus fentanyl on pain relief for pediatric orthopedic emergencies: A meta-analysis of randomized controlled studies. ( Qiu, J; Xie, M, 2021)
" The patient is a 50-year-old female with widely metastatic breast cancer who developed opioid toxicity when maintenance transdermal fentanyl patch therapy (100 μg patch applied every 72 h) was rotated to subcutaneous hydromorphone infusion to improve pain control."9.12Opioid rotation from transdermal fentanyl to continuous subcutaneous hydromorphone in a cachectic patient: A case report and review of the literature. ( Chua, D; Jackson, LD; Selby, D; Wortzman, R, 2021)
"This trial demonstrated that the lower 12 microg/h dose of fentanyl TTS provided a therapeutic benefit in non-malignant chronic pain, with a similar AE rate but a lower drop-out rate than that seen in trials at higher doses."9.12A Phase III study to assess the clinical utility of low-dose fentanyl transdermal system in patients with chronic nonmalignant pain. ( Otis, J; Rothman, M, 2006)
"We compare the efficacy of intranasal fentanyl versus intravenous morphine in a pediatric population presenting to an emergency department (ED) with acute long-bone fractures."9.12A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department. ( Borland, M; Jacobs, I; King, B; O'Brien, D, 2007)
"Fifty-six adults with chronic noncancer pain using oral transmucosal fentanyl citrate (OTFC, ACTIQ)."9.12Impact of breakthrough pain on quality of life in patients with chronic, noncancer pain: patient perceptions and effect of treatment with oral transmucosal fentanyl citrate (OTFC, ACTIQ). ( Chun, SY; Fortner, B; Reinking, J; Shoemaker, S; Stegman, M; Taylor, DR; Webster, LR, 2007)
"Patients experiencing pain during daily dressing changes were given entonox plus either placebo or oral transmucosal fentanyl citrate (OTFC) for two consecutive dressing changes in a randomised double-blind placebo-controlled crossover trial."9.12Oral transmucosal fentanyl citrate versus placebo for painful dressing changes: a crossover trial. ( Barker, L; Larsen, D; MacIntyre, PA; Margetts, L, 2007)
"The use of OTFC can provide improved pain control when compared with IV morphine."9.12A randomized clinical trial of oral transmucosal fentanyl citrate versus intravenous morphine sulfate for initial control of pain in children with extremity injuries. ( Christopher, NC; Kennedy, CS; Mahar, PJ; Rana, JA, 2007)
"To compare the pain relief achieved with nebulized fentanyl citrate with intravenous (i."9.12Randomized clinical trial of nebulized fentanyl citrate versus i.v. fentanyl citrate in children presenting to the emergency department with acute pain. ( Biros, MH; Herold, M; Hubbard, D; Kletti, C; Miner, JR, 2007)
" In this randomized open-label study the influence of tramadol on dose adjustment of transdermal fentanyl in advanced cancer pain control was prospectively evaluated."9.12Improved cancer pain treatment using combined fentanyl-TTS and tramadol. ( Aloisio, L; Bajocco, C; Ciccozzi, A; Coaccioli, S; Colangeli, A; Marinangeli, F; Paladini, A; Varrassi, G, 2007)
"Various strategies have been studied to reduce the discomfort of rocuronium pain."9.12Effect of narcotic pretreatment on pain after rocuronium injection: a randomized, double-blind controlled comparison with lidocaine. ( Bithal, PK; Chauhan, H; Dash, HH; Prabhakar, H; Rath, GP; Singh, M, 2007)
"To compare the effects of providing analgesia with either transdermal fentanyl (TTS-fentanyl) or paracetamol and codeine (P/C) in addition to radiotherapy in patients with metastatic bone pain."9.11Radiotherapy plus either transdermal fentanyl or paracetamol and codeine for painful bone metastases: a randomised study of pain relief and quality of life. ( Eleftheriadis, N; Georgakopoulos, G; Gompakis, N; Kouloulias, VE; Kouvaris, J; Mystakidou, K; Pistevou-Gompaki, K; Varveris, C, 2004)
"To determine the safety and efficacy of transdermal fentanyl for pain relief in cancer patients and to compare the effects on patients according to whether they had previously received strong opioids, weak opioids or non-opioid analgesia."9.11Use of transdermal fentanyl without prior opioid stabilization in patients with cancer pain. ( Bryuzgin, V; Kourteva, G; Tawfik, MO, 2004)
"The aim of this observational study was to examine pain management outcomes and quality of life (QoL) measures in cancer patients with intolerable or chronic severe pain transferring from World Health Organization's step I, II, and III analgesics to the transdermal therapeutic fentanyl system (TTS-F)."9.11Pain management of cancer patients with transdermal fentanyl: a study of 1828 step I, II, & III transfers. ( Georgaki, S; Katsouda, E; Kouloulias, V; Kouvaris, J; Mystakidou, K; Parpa, E; Tsilika, E; Vlahos, L, 2004)
"This study sought to compare the analgesic efficacy and safety of patient controlled intra-nasal (PCIN) fentanyl with oral morphine for procedural wound care in burns patients."9.11A randomised crossover trial of patient controlled intranasal fentanyl and oral morphine for procedural wound care in adult patients with burns. ( Finn, J; Fong, J; Gelavis, A; Leslie, G; Mackenzie, E; Wood, F; Wright, J, 2004)
"Sufentanil, a potent mu-opioid agonist, historically has not been been given systemically to treat chronic pain."9.11Relative analgesic potency of fentanyl and sufentanil during intermediate-term infusions in patients after long-term opioid treatment for chronic pain. ( Charapata, S; DuPen, S; Fisher, DM; Heinze, E; Katz, N; Portenoy, R; Rauck, R; Reynolds, L; Wallace, M; Webster, L, 2004)
"Fentanyl is commonly used for spinal analgesia during labour but it is associated with a high incidence of pruritus."9.11Intrathecal fentanyl-induced pruritus during labour: the effect of prophylactic ondansetron. ( Evans, SF; Paech, MJ; Wells, J, 2004)
"We treated 50 patients with chronic nonmalignant pain using transdermal fentanyl (TDF) 25 microg/hr and concurrently measured pain using a visual analog scale (VAS) and serum cortisol concentration."9.11The effect of transdermal fentanyl treatment on serum cortisol concentrations in patients with non-cancer pain. ( Altan, A; Ozyuvaci, E; Yanmaz Alnigenis, N, 2004)
"We investigated the early recovery characteristics and pain relief of adult patients during combined anesthesia with (epidural and general), either with propofol or sevoflurane for maintenance in major abdominal surgery."9.11Propofol and sevoflurane during epidural/general anesthesia: comparison of early recovery characteristics and pain relief. ( Duru, S; Elar, Z; Hepağuşlar, H; Ozkardeşler, S; Ozzeybek, D; Taşdöğen, A, 2004)
"This study evaluated transdermal fentanyl (TDF) for the treatment of pain from rheumatoid arthritis (RA) which was not adequately controlled by nonopioid analgesics and/or weak opioids."9.11Transdermal fentanyl for the treatment of pain caused by rheumatoid arthritis. ( Bjorneboe, O; Herrero-Beaumont, G; Richarz, U, 2004)
" Fentanyl also may reduce the pain of diazepam injection by blocking the opiate receptors in vessels walls."9.11The effect of ketamine and fentanyl in reducing the pain of diazepam injection. ( Azemati, M; Azemati, S; Khosravi, A; Khosravi, MB, 2004)
"To evaluate the effectiveness and safety of transdermal fentanyl (TDF) for the treatment of pain associated with rheumatoid arthritis (RA) or osteoarthritis of the knee or hip (OA), which was not adequately controlled by non-opioid analgesics and/or weak opioids."9.11Benefits of transdermal fentanyl in patients with rheumatoid arthritis or with osteoarthritis of the knee or hip: an open-label study to assess pain control. ( Bjorneboe, O; Herrero-Beaumont, G; Le Loet, X; Pavelka, K; Richarz, U, 2004)
"This study was designed to evaluate the utility of transdermal fentanyl (TDF, Durogesic) for the treatment of pain due to osteoarthritis (OA) of the knee or hip, which was not adequately controlled by non-opioid analgesics or weak opioids."9.11Transdermal fentanyl for the treatment of pain caused by osteoarthritis of the knee or hip: an open, multicentre study. ( Le Loët, X; Pavelka, K; Richarz, U, 2005)
"We evaluated the effects of gabapentin and carbamazepine for pain relief in 36 Guillain-Barré syndrome patients."9.11The comparative evaluation of gabapentin and carbamazepine for pain management in Guillain-Barré syndrome patients in the intensive care unit. ( Kumar, A; Navkar, DV; Pandey, CK; Raza, M; Singh, UK; Tripathi, M, 2005)
"Chronic pain can be effectively treated with fentanyl-TTS, which has a very favorable side effect profile."9.11[Individual aspects of the quality of life of patients with chronic pain. Observational study of treatment with fentanyl-TTS]. ( Waap, I; Zimmermann, M, 2005)
"When compared with rocuronium alone, only the addition of saline failed to significantly reduce the pain reported by patients."9.10Comparison of four strategies to reduce the pain associated with intravenous administration of rocuronium. ( Chiarella, AB; Clanachan, AS; Huston, CM; Jolly, DT, 2003)
"The findings suggest that a single lumbar epidural dose of fentanyl should be injected at the spinal interspace corresponding to the dermatomal site of pain."9.10Lumbar epidural fentanyl: segmental spread and effect on temporal summation and muscle pain. ( Arendt-Nielsen, L; Curatolo, M; Eichenberger, U; Giani, C; Graven-Nielsen, T; Petersen-Felix, S, 2003)
"To determine the effects of systemic fentanyl analgesia in preventing the pain related to the administration of retrobulbar anesthesia and cataract surgery."9.10Effects of fentanyl on pain and hemodynamic response after retrobulbar block in patients having phacoemulsification. ( Ermis, SS; Inan, UU; Oztürk, F; Sivaci, RG, 2003)
"To measure the plasma fentanyl concentrations achieved over time with transdermal fentanyl patches in awake cats and cats undergoing anesthesia and ovariohysterectomy."9.10Plasma fentanyl concentrations in awake cats and cats undergoing anesthesia and ovariohysterectomy using transdermal administration. ( Allen, SW; Egger, CM; Glerum, LE; Haag, M, 2003)
"This randomised, multicentre, direct open comparative trial evaluated the efficacy, treatment convenience, tolerability and safety aspects of transdermal therapeutic system (TTS)-fentanyl and sustained-release oral morphine (SRM) in both opioid-naïve patients with moderate-to-severe cancer-related pain and in patients who had already been using opioids for mild-to-moderate pain."9.10Comparison of TTS-fentanyl with sustained-release oral morphine in the treatment of patients not using opioids for mild-to-moderate pain. ( Schipper, RM; Smit, JM; van Seventer, R; Wicks, MA; Zuurmond, WW, 2003)
"Transdermal therapeutic system-fentanyl (TTS-F) has been extensively studied in cancer pain management."9.10Long-term management of noncancer pain with transdermal therapeutic system-fentanyl. ( Georgaki, S; Mavromati, A; Mystakidou, K; Parpa, E; Smyrniotis, V; Tsilika, E; Vlahos, L, 2003)
"Analgesic treatment with TTS fentanyl used as a single opioid is effective and safe for cancer pain relief, given that is cautiously applied, in patients requiring strong opioid analgesics even if they were naive to strong or mild opioids."9.10Use of TTS fentanyl as a single opioid for cancer pain relief: a safety and efficacy clinical trial in patients naive to mild or strong opioids. ( Befon, S; Dardoufas, K; Georgaki, S; Mystakidou, K; Tsilika, E; Vlahos, L, 2002)
"The successful use of methadone in cancer pain has been supported by numerous case reports and clinical studies."9.10Pitfalls of opioid rotation: substituting another opioid for methadone in patients with cancer pain. ( Derby, S; Fischberg, D; Kornick, C; Manfredi, PL; Moryl, N; Payne, R; Santiago-Palma, J, 2002)
" In the postanesthesia care unit (PACU), fentanyl 25 microg was administered for a verbal analog scale (VAS) pain score >or=3."9.10Preoperative administration of controlled-release oxycodone for the management of pain after ambulatory laparoscopic tubal ligation surgery. ( Joshi, W; Maciolek, H; Reuben, SS; Steinberg, RB, 2002)
"We compared the efficacy of ondansetron, lidocaine, tramadol, and fentanyl in minimizing pain caused by the injection of rocuronium in 250 patients."9.10The prevention of pain from injection of rocuronium by ondansetron, lidocaine, tramadol, and fentanyl. ( Karamanlioğlu, B; Memiş, D; Pamukçu, Z; Süt, N; Turan, A, 2002)
"Constipation and the use of laxatives were investigated in patients with chronic cancer pain treated with oral morphine and transdermal fentanyl in an open sequential trial."9.09Constipation and the use of laxatives: a comparison between transdermal fentanyl and oral morphine. ( Grond, S; Kasper, M; Kulbe, C; Lehmann, KA; Loick, G; Radbruch, L; Sabatowski, R, 2000)
"Transdermal Fentanyl (TF, Durogesic) is a strong opioid analgesic which is used in the treatment of cancer pain."9.09[Research from the Palliative Care Department in Poznań on treatment of neoplasm pain with Durogesic (transdermal fentanyl)]. ( Gorzelińska, L; Kozikowska, J; Leppert, W; Luczak, J, 2000)
"To compare patients' preference for transdermal fentanyl or sustained release oral morphine, their level of pain control, and their quality of life after treatment."9.09Randomised crossover trial of transdermal fentanyl and sustained release oral morphine for treating chronic non-cancer pain. ( Allan, L; Bolt, M; de Waroux, BL; Donald, R; Hays, H; Jensen, NH; Kalso, E, 2001)
"Our aim was to find out whether intravenous fentanyl was effective in reducing the pain of first-trimester abortion."9.09A randomized controlled trial of fentanyl for abortion pain. ( Rawling, MJ; Wiebe, ER, 2001)
"This open-label study evaluated the long-term safety and tolerability of oral transmucosal fentanyl citrate (OTFC) in ambulatory cancer patients with breakthrough pain undergoing cancer care at 32 university- or community-based practices."9.09Long-term safety of oral transmucosal fentanyl citrate for breakthrough cancer pain. ( Berris, R; Busch, MA; Coluzzi, P; Hart, L; Loseth, DB; Lyss, A; Nordbrook, E; Payne, R; Portenoy, RK; Rauck, R; Simmonds, M, 2001)
"The effects of sublingual fentanyl citrate (SLFC) were assessed in 11 hospice inpatients with cancer-related breakthrough pain."9.09Sublingual fentanyl citrate for cancer-related breakthrough pain: a pilot study. ( Zeppetella, G, 2001)
"To investigate the efficacy and safety of oral transmucosal fentanyl (OTFC) in providing analgesia and sedation for painful diagnostic procedures in children."9.08The use of oral transmucosal fentanyl citrate for painful procedures in children. ( Bernstein, B; Conard, PL; Rosenblum, M; Schechter, NL; Weisman, SJ, 1995)
"Direct conversion from oral morphine to transdermal fentanyl with a ratio of oral morphine/transdermal fentanyl (100:1 mg) daily was examined in patients with cancer pain."9.08Direct conversion from oral morphine to transdermal fentanyl: a multicenter study in patients with cancer pain. ( Donner, B; Strumpf, M; Tryba, M; Zenz, M, 1996)
"We performed an open-label pilot study to define analgesic efficacy, acceptability, and toxicity of transdermal fentanyl in an ambulatory population of patients with cancer pain."9.08Transdermal fentanyl in the management of cancer pain in ambulatory patients: an open-label pilot study. ( Fidler, P; Hammack, JE; Loprinzi, CL; Mailliard, JA; Michalak, JC; Miser, AW; O'Fallon, JR; Reuter, NF; Rospond, RM; Wilwerding, MB, 1996)
"To compare the local efficacy of lidocaine and fentanyl in reducing propofol injection pain (PIP), we conducted a prospective randomized double-blind study in 75 ASA I and II adult patients."9.08Reduction of propofol pain--fentanyl vs lidocaine. ( Alyafi, WA; Rangasami, J, 1996)
"We compared the analgesic effect of intravenous dose titration of fentanyl with diazepam (active placebo) or saline (inert placebo) in 53 patients with different types of neuropathic pain."9.08Randomised double-blind active-placebo-controlled crossover trial of intravenous fentanyl in neuropathic pain. ( Dellemijn, PL; Vanneste, JA, 1997)
"A prospective phase II study was conducted to define the analgesic efficacy, acceptability and toxicity of the transdermal therapeutic system (TTS) of fentanyl in Chinese patients with severe cancer-related pain."9.08Transdermal fentanyl for severe cancer-related pain. ( Chan, AT; Johnson, PJ; Lam, KK; Leung, TW; Nip, SY; Yeo, W, 1997)
"To compare pain-related treatment satisfaction, patient-perceived side effects, functioning, and well-being in patients with advanced cancer who were receiving either transdermal fentanyl (Duragesic, Janssen Pharmaceuticals, Titusville, NJ) or sustained-release oral forms of morphine (MS Contin, Perdue Frederick Co, Norwalk, CT, or Oramorph SR, Roxanne Laboratories, Columbus, OH)."9.08Quality of life and cancer pain: satisfaction and side effects with transdermal fentanyl versus oral morphine. ( Mahmoud, R; Mathias, SD; Pasta, DJ; Payne, R; Wanke, LA; Williams, R, 1998)
") retention of fentanyl and lidocaine in reducing the pain on i."9.08Comparison of intravenous retention of fentanyl and lidocaine on local analgesia in propofol injection pain. ( Chang, DP; Chung, YT; Hong, MH; Huang, S; Lin, SS; Pang, WW, 1997)
"Patients who were 18 years of age or older, receiving the equivalent of at least 60 mg oral morphine or at least 50 microg transdermal fentanyl per day for chronic cancer-related pain, and experiencing at least one episode of breakthrough pain per day were studied."9.08Oral transmucosal fentanyl citrate: randomized, double-blinded, placebo-controlled trial for treatment of breakthrough pain in cancer patients. ( Busch, M; Cleary, J; Farrar, JT; Nordbrock, E; Rauck, R, 1998)
"Pain on injection is one of the well-known side effects of propofol."9.08[Pain-free injection of propofol]. ( Ichimiya, T; Kamada, Y; Kobayashi, Y; Kumagai, A; Namiki, A; Seki, S; Tsuchida, H, 1998)
"We compared the effect of fentanyl and lidocaine on pain during injection of propofol."9.08[Reduction of pain on injection of propofol: a comparison of fentanyl with lidocaine]. ( Aketa, K; Ichimiya, T; Kobayashi, Y; Naganuma, R; Namiki, A; Seki, S, 1998)
"This was a multicenter, randomized, double-blind, dose-titration study in 62 adult cancer patients using transdermal fentanyl for persistent pain."9.08Dose-titration, multicenter study of oral transmucosal fentanyl citrate for the treatment of breakthrough pain in cancer patients using transdermal fentanyl for persistent pain. ( Busch, MA; Christie, JM; Coluzzi, P; Nordbrock, E; Patt, R; Portenoy, RK; Simmonds, M, 1998)
"All communications on the use of transdermal fentanyl as well as the recommendations of the manufacturer include the direction that patients should be titrated with a short-acting narcotic to control their cancer pain before they are converted to a fentanyl transdermal therapeutic system (TTS)."9.07Transdermal fentanyl in uncontrolled cancer pain: titration on a day-to-day basis as a procedure for safe and effective dose finding--a pilot study in 20 patients. ( Korte, W; Morant, R, 1994)
"At Helsinki University Central Hospital in Finland, clinical researchers divided 169 women into two groups (group 1: diagnostic laparoscopies; group 2: laparoscopic sterilizations) as part of a study to evaluate the effect of intravenous diclofenac on postoperative pain, nausea, and recovery after outpatient gynecological laparoscopy."9.07Effect of intravenous diclofenac on pain and recovery profile after day-case laparoscopy. ( Hovorka, J; Kallela, H; Korttila, K, 1993)
"The effect of fentanyl, administered immediately before propofol, when pain is experienced at the site of propofol injection was studied in 28 children undergoing elective surgery."9.07[Fentanyl prevents the pain at the site of propofol injection]. ( Chessa, D; Cossu, F; Serra, G, 1992)
"In this study, 6 patients with pain from advanced cancer were enrolled in a multicenter, open-label seeding trial of transdermal fentanyl."9.07Transdermal fentanyl: seeding trial in patients with chronic cancer pain. ( Kedziera, P; Levy, MH; Rosen, SM, 1992)
"Patients were entered into an open label study to evaluate the efficacy of transdermal fentanyl as an analgesic for chronic cancer pain."9.07Transdermal fentanyl for chronic cancer pain: detailed case reports and the influence of confounding factors. ( Hogan, LA; Patt, RB, 1992)
"In this study, 11 cancer patients who experienced severe pain were treated with transdermal fentanyl."9.07Transdermal fentanyl use in hospice home-care patients with chronic cancer pain. ( Herbst, LH; Strause, LG, 1992)
"A multicenter study was conducted to determine the patient and physician acceptability of transdermal fentanyl in the management of cancer-related pain."9.07Management of cancer pain with transdermal fentanyl: phase IV trial, University of Iowa. ( Barcellos, WA; Maves, TJ, 1992)
"To evaluate the efficacy of opiate administration regimens, 32 patients with multiple rib fractures were prospectively randomized to receive either continuous epidural (ED) or continuous intravenous (IV) infusions of fentanyl."9.07Prospective evaluation of epidural and intravenous administration of fentanyl for pain control and restoration of ventilatory function following multiple rib fractures. ( Davis, JW; Hoyt, DB; Karagianes, TG; Mackersie, RC, 1991)
"To systematically compare the efficacy and safety of sufentanil versus fentanyl for pain relief in labor involving combined spinal-epidural analgesia (CSEA), a systematic review and meta-analysis of randomized controlled trials targeting parturients requesting labor analgesia was conducted."9.05Sufentanil versus fentanyl for pain relief in labor involving combined spinal-epidural analgesia: a systematic review and meta-analysis of randomized controlled trials. ( Diao, Y; Geng, S; Huang, Z; Liu, S; Liu, Y; Shen, L; Su, X; Sun, J; Zhi, M, 2020)
"To compare the incidence and severity of pain and myoclonus, 83 patients, premedicated with oral diazepam, received a double-blind intravenous injection of either droperidol 5 mg, fentanyl 0."9.05Pain and myoclonus during induction with etomidate. A double-blind, controlled evaluation of the influence of droperidol and fentanyl. ( Adam, AA; Giezen, J; Helmers, JH, 1981)
"Forty subjects rated the magnitude of painful electrical stimulation of tooth pulp before and after the intravenous administration of either fentanyl, a short-acting narcotic, or a saline placebo."9.04Narcotic analgesia: fentanyl reduces the intensity but not the unpleasantness of painful tooth pulp sensations. ( Dubner, R; Gracely, RH; McGrath, PA, 1979)
"The objectives of this review were to assess the ability of both pharmacological and non-pharmacological interventions to reduce or eliminate the pain that accompanies rocuronium bromide administration."8.93Pharmacological and non-pharmacological interventions for reducing rocuronium bromide induced pain on injection in children and adults. ( Ali, Z; Kalaivani, M; Prabhakar, H; Singh, GP; Smith, MA, 2016)
" This rapid review, commissioned by the National Institute for Health Research, used standard Cochrane methodology to examine adverse effects of morphine, fentanyl, oxycodone, and codeine in cancer pain studies as a close approximation to possible effects in the dying patient."8.90Impact of morphine, fentanyl, oxycodone or codeine on patient consciousness, appetite and thirst when used to treat cancer pain. ( Derry, S; Moore, RA; Wiffen, PJ, 2014)
"To determine the analgesic efficacy of transdermal fentanyl for relief of cancer pain, and to assess the adverse events associated with the use of transdermal fentanyl for relief of cancer pain."8.89Transdermal fentanyl for cancer pain. ( Derry, S; Hadley, G; Moore, RA; Wiffen, PJ, 2013)
"The findings indicate comparability of transdermal buprenorphine and transdermal fentanyl for pain measures with significantly fewer adverse events (nausea and treatment discontinuation due to adverse events) caused by transdermal buprenorphine."8.88Systematic review of efficacy and safety of buprenorphine versus fentanyl or morphine in patients with chronic moderate to severe pain. ( Aune, D; Hernandez, AV; Kleijnen, J; Misso, K; Riemsma, R; Truyers, C; Wolff, RF, 2012)
"To evaluate the long-term dosing, safety, and tolerability of fentanyl buccal tablet (FBT) in a large cohort of opioid-tolerant patients with chronic noncancer pain and breakthrough pain (BTP)."8.87Long-term dosing, safety, and tolerability of fentanyl buccal tablet in the management of noncancer-related breakthrough pain in opioid-tolerant patients. ( Janka, L; Nalamachu, SR; Narayana, A, 2011)
"Oral transmucosal fentanyl citrate (OTFC) and fentanyl buccal tablets are the first medications developed specifically for the treatment of breakthrough pain in opioid-tolerant patients."8.87Fentanyl nasal spray for the treatment of cancer pain. ( Gouliamos, A; Mystakidou, K; Panagiotou, I, 2011)
"A short cut review was carried out to establish whether intranasal fentanyl is better than parenteral morphine for managing acute severe pain in children."8.87Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Bet 4: is intranasal fentanyl better than parenteral morphine for managing acute severe pain in children? ( Kusre, SR, 2011)
"To compare the efficacy of intranasal fentanyl spray (INFS), oral transmucosal fentanyl citrate (OTFC), fentanyl buccal tablet (FBT) and oral morphine (OM) for the treatment of breakthrough cancer pain (BTCP)."8.86Efficacy of intranasal fentanyl spray versus other opioids for breakthrough pain in cancer. ( Jansen, J; Lenre, M; Nolte, T; Stam, W; Vissers, D, 2010)
"Previous meta-analysis suggested that transdermal fentanyl was not inferior to sustained-release oral morphine in treating moderate-severe cancer pain with less adverse effects."8.86Efficacy and adverse effects of transdermal fentanyl and sustained-release oral morphine in treating moderate-severe cancer pain in Chinese population: a systematic review and meta-analysis. ( Bi, ZF; Chen, DL; Jiang, ZM; Ma, W; Xie, DR; Yang, Q; Zhang, YD, 2010)
"Review key aspects of breakthrough pain management with fentanyl buccal tablet, with a focus on minimizing risk to optimize therapeutic outcomes."8.86Treatment of breakthrough pain with fentanyl buccal tablet in opioid-tolerant patients with chronic pain: appropriate patient selection and management. ( Fine, PG; Narayana, A; Passik, SD, 2010)
"Transdermal fentanyl patches first became available in the early 1990s and provided an innovative treatment for the management of cancer pain."8.85The role of transdermal fentanyl patches in the effective management of cancer pain. ( Gibbs, M, 2009)
"The safety of transdermal fentanyl (TF) in comparison with slow-release oral morphine (SROM) in moderate-severe pain was assessed."8.85Transdermal fentanyl as a front-line approach to moderate-severe pain: a meta-analysis of randomized clinical trials. ( Maltoni, M; Santelmo, C; Sartori, S; Scarpi, E; Tamburini, E; Tassinari, D; Tombesi, P, 2009)
"In the present study, we demonstrated that repeated treatment with fentanyl, but not morphine or oxycodone, causes a rapid desensitization to its ability to block the hyperalgesia associated with the attenuation of mu-opioid receptor resensitization in mice in a chronic pain-like state."8.84[Difference in tolerance to anti-hyperalgesic effect and its molecular mechanisms between chronic treatment with morphine, fentanyl and oxycodone in a chronic pain-like state]. ( Hashimoto, S; Kuzumaki, N; Nakamura, A; Narita, M; Ozeki, A; Satoshi, I; Suzuki, T; Uezono, Y, 2008)
"To assess the adverse effects of transdermal opiates treating moderate-severe cancer pain in comparison with slow release oral morphine."8.84Adverse effects of transdermal opiates treating moderate-severe cancer pain in comparison to long-acting morphine: a meta-analysis and systematic review of the literature. ( Maltoni, M; Raffaeli, W; Sartori, S; Scarpi, E; Tamburini, E; Tassinari, D; Tombesi, P, 2008)
"Transdermal buprenorphine has been assessed as a therapy for chronic cancer and non-cancer pain in both clinical and postmarketing surveillance studies."8.83Transdermal buprenorphine in cancer pain and palliative care. ( Sittl, R, 2006)
"The fentanyl buccal tablet (FBT) is a new formulation of fentanyl that uses an effervescent drug delivery system to enhance penetration across the buccal mucosa for the treatment of breakthrough pain in opioid-tolerant patients with cancer."8.83Fentanyl buccal tablet: in breakthrough pain in opioid-tolerant patients with cancer. ( Blick, SK; Wagstaff, AJ, 2006)
"Transdermal fentanyl is effective and well tolerated for the treatment of chronic pain caused by malignancy and non-malignant conditions when administered according to the manufacturer's recommendations."8.82Benefit-risk assessment of transdermal fentanyl for the treatment of chronic pain. ( Kornick, CA; Moryl, N; Obbens, EA; Payne, R; Santiago-Palma, J, 2003)
"To evaluate effectiveness and safety information of transdermal fentanyl (TDF) (Duragesic/Durogesic) and sustained-release oral morphine (SRM) in cancer pain (CP) and chronic non-cancer pain (NCP), a pooled analysis was conducted on datasets of published, open label, uncontrolled (no comparator group) and randomised controlled (with SRM as comparator) studies of TDF."8.82Efficacy and safety of transdermal fentanyl and sustained-release oral morphine in patients with cancer and chronic non-cancer pain. ( Ahmedzai, SH; Allan, LG; Camacho, F; Clark, AJ; Horbay, GL; Richarz, U; Simpson, K, 2004)
"Transdermal fentanyl is a useful opioid-agonist for the treatment of moderate to severe chronic cancer pain."8.81Transdermal fentanyl: an updated review of its pharmacological properties and therapeutic efficacy in chronic cancer pain control. ( Muijsers, RB; Wagstaff, AJ, 2001)
"Transdermal fentanyl appears to be a safe and practical alternative to short-acting analgesics in the treatment of cancer pain."8.78Transdermal fentanyl in cancer pain. ( Mosser, KH, 1992)
"The physicochemical properties, pharmacology, pharmacokinetics, serum concentrations and clinical effects, adverse effects and contraindications, and dosage of transdermally administered fentanyl are described, and clinical studies evaluating the use of a transdermal fentanyl system in the treatment of postoperative pain and chronic cancer-associated pain are reviewed."8.78Transdermally administered fentanyl for pain management. ( Calis, KA; Corso, DM; Kohler, DR, 1992)
"Fentanyl transdermal therapy is a suitable treatment for moderate-to-severe cancer-related pain."8.31An individualized digital twin of a patient for transdermal fentanyl therapy for chronic pain management. ( Bahrami, F; De Nys, K; Defraeye, T; Rossi, RM, 2023)
"Fentanyl is a potent analgesic with a rapid onset and short half-life that make it a useful treatment for pain and a lethal drug of abuse."8.31Continuous fentanyl administration and spontaneous withdrawal decreases home cage wheel running in rats with and without hindpaw inflammation. ( Hilgendorf, TN; Kandasamy, R; Morgan, MM, 2023)
"The aim of this study was to assess the safety of fentanyl analgosedation during therapeutic hypothermia, by evaluating severe adverse effects and possible correlation with the neurodevelopmental outcome."8.12Fentanyl analgesia in asphyxiated newborns treated with therapeutic hypothermia. ( Bedetti, L; Berardi, A; Della Casa, E; Ferrari, F; Garetti, E; Guidotti, I; Iughetti, L; Lago, P; Lucaccioni, L; Lugli, L; Pugliese, M; Roversi, MF; Spada, C, 2022)
"This is a study that is based on network pharmacology, focusing on the pharmacological mechanism of fentanyl in easing pain."8.12Study on the Mechanism of Fentanyl in Pain Treatment Based on Network Pharmacology. ( Bi, J; Wan, H; Wang, S; Zhao, J; Zhao, W; Zhou, S, 2022)
"It is recommended not to use transdermal fentanyl (Fe) patches (TFP) in cancer cachexia but TFP may be the only available option for pain."8.12Transdermal fentanyl to parenteral morphine route switch and drug rotation in refractory cancer cachexia. ( Alabdullateef, SH; Almashiakhi, M; Alsirafy, SA; Elyamany, AM; Hassan, AD, 2022)
"Nebulized fentanyl is well established for analgesia but its use for dyspnea requires further investigation."7.96Nebulized Fentanyl for Dyspnea: A Retrospective Chart Review. ( Cain, J; Coyne, PJ; Dulin, JD; Higgins, EA; Miller, MM; Overstreet, AN; Vaughan, L; Young, AM, 2020)
"Sprague-Dawley rats (11-13 weeks) were randomly assigned to control (saline vehicle), fentanyl, or ketamine-treated groups with or without hemorrhage (n = 8 or 9 for each group)."7.96Fentanyl impairs but ketamine preserves the microcirculatory response to hemorrhage. ( Calderon, AS; Hinojosa-Laborde, C; Klemcke, HG; Ryan, KL; Scott, LL; Xiang, L, 2020)
"Fentanyl has been associated with many drug overdose deaths; its presence in many street drugs has been postulated to be increasing."7.96Correlation of Fentanyl Positive Drug Screens with Other Medications in Patients from Pain, Rehabilitation and Behavioral Programs. ( Greg Ackerman, RT; Krock, K; Nickley, J; Pesce, A; Tran, K, 2020)
"To test the effectiveness of a premedication protocol using intravenous bolus of 100 μg fentanyl to reduce pain associated with femoral artery closure device placement for neuro-endovascular procedures."7.91Effectiveness of premedication protocol using intravenous fentanyl to reduce pain associated with femoral artery closure device placement. ( Naseem, N; Qureshi, AI; Saleem, MA; Wallery, SS, 2019)
" Even after multiple testing with Bonferroni adjustments, an increase in the analgesic effect of fentanyl in the cold pressor-induced pain test was significantly associated with a greater number of the A allele of the rs7583431 SNP (linear regression, P = ."7.88Association between the rs7583431 single nucleotide polymorphism close to the activating transcription factor 2 gene and the analgesic effect of fentanyl in the cold pain test. ( Aoki, Y; Fukuda, KI; Hasegawa, J; Hayashida, M; Ichinohe, T; Ikeda, K; Kasai, S; Koukita, Y; Nishizawa, D; Takahashi, K; Yoshida, K, 2018)
"Our aim was to evaluate a nurse-initiated pain-management protocol in adult patients with traumatic injuries in the short and in the long term, utilizing fentanyl for severe pain."7.85Emergency Department Pain Management in Adult Patients With Traumatic Injuries Before and After Implementation of a Nurse-Initiated Pain Treatment Protocol Utilizing Fentanyl for Severe Pain. ( Goslings, JC; Hollmann, MW; Lirk, P; Ridderikhof, ML; Schep, NW; Schyns, FJ, 2017)
"To assess the effectiveness of nebulized fentanyl used for analgesia in renal colic."7.85A retrospective analysis of nebulized versus intravenous fentanyl for renal colic. ( Aygun, A; Bekar, O; Cicek, M; Erdem, E; Imamoglu, M; Karaca, Y; Sahin, A; Tatli, O; Turedi, S; Turkmen, S, 2017)
"To explore analgesic effects of fentanyl and butorphanol on incisional pain in rats and to investigate the pharmacological mechanism of combination."7.83Analgesic effect and pharmacological mechanism of fentanyl and butorphanol in a rat model of incisional pain. ( Chen, Q; Li, P; Liu, GL; Shang, Y; Xu, Y, 2016)
"Little is known about the efficacy of low-dose transdermal fentanyl (TDF) patches in opioid-naïve patients with moderate-to-severe cancer pain."7.81The efficacy of low-dose transdermal fentanyl in opioid-naïve cancer patients with moderate-to-severe pain. ( Hwang, IG; Kang, JH; Kim, JH; Kim, WS; Lee, HR; Lee, HY; Lee, KE; Oh, SY; Park, K; Park, SH; Park, YS; Song, SY, 2015)
"This study aims to determine whether a pathway designed to facilitate the use of intranasal (IN) fentanyl for long-bone fractures will expedite the delivery of pain medication, decrease the total length of emergency department (ED) stay, and provide faster analgesia compared with intravenous (IV) morphine."7.81Expedited Delivery of Pain Medication for Long-Bone Fractures Using an Intranasal Fentanyl Clinical Pathway. ( Erikson Ramirez, D; Frazier, SB; Perkins, AM; Schacherer, NM, 2015)
"Intranasal fentanyl seems to be efficient for analgesia in adult patients with renal colic."7.81Does intranasal fentanyl provide efficient analgesia for renal colic in adults? ( Bakkali, H; Belkouch, A; Belyamani, L; Chouaib, N; Elbouti, A; Rafai, M; Sirbou, R; Zidouh, S, 2015)
"Common adverse symptoms of cancer and chemotherapy are a major health burden; chief among these is pain, with opioids including transdermal fentanyl the mainstay of treatment."7.81Innate Immune Signalling Genetics of Pain, Cognitive Dysfunction and Sickness Symptoms in Cancer Pain Patients Treated with Transdermal Fentanyl. ( Barratt, DT; Dale, O; Kaasa, S; Klepstad, P; Somogyi, AA, 2015)
" infusion of fentanyl in patients with hepatocellular carcinoma (HCC) treated by RFA."7.80Pain control in patients with hepatocellular carcinoma treated by percutaneous radiofrequency ablation: comparison of the efficacy of one-shot and continuous intravenous fentanyl delivery. ( Ikeda, O; Inoue, S; Kawanaka, K; Nakasone, Y; Tamura, Y; Yamashita, Y; Yokoyama, K, 2014)
"It is unknown whether nutritional status influences pain intensity in cancer patients receiving a transdermal fentanyl patch (FP)."7.80A retrospective study on the influence of nutritional status on pain management in cancer patients using the transdermal fentanyl patch. ( Chiba, T; Kimura, Y; Kudo, K; Tairabune, T; Takahashi, H; Takahashi, K; Wakabayashi, G, 2014)
"This study evaluated the efficacy, safety, and quality of life (QoL) measure of transdermal fentanyl (TDF) for moderate-to-severe pain due to oral mucositis caused by chemoradiotherapy in patients with advanced nasopharyngeal carcinoma (NPC)."7.80Transdermal fentanyl for pain due to chemoradiotherapy-induced oral mucositis in nasopharyngeal cancer patients: evaluating efficacy, safety, and improvement in quality of life. ( Feng, HX; Guo, SP; He, ZY; Li, FY; Sun, JY; Wu, SG; Wu, YJ; Zhou, J, 2014)
"Cold pain sensitivity and analgesic effects of fentanyl were related to the SNP and haplotypes of the P2RX7 gene."7.80Haplotypes of P2RX7 gene polymorphisms are associated with both cold pain sensitivity and analgesic effect of fentanyl. ( Fukuda, K; Hasegawa, J; Hayashida, M; Ide, S; Ikeda, K; Kasai, S; Minami, M; Nishizawa, D, 2014)
"Morphine, oxycodone, and fentanyl are commonly used to control cancer pain."7.80Influence of serum albumin levels during opioid rotation from morphine or oxycodone to fentanyl for cancer pain. ( Arakawa, Y; Fukuura, K; Futamura, A; Hayashi, T; Higashiguchi, T; Ikehata, S; Kuki, R; Makihara, T; Matsuzaki, H; Mori, N; Takahashi, H; Yamadaa, S; Yasuda, K, 2014)
"Palliative care physicians are accustomed to using transdermal fentanyl patch for cancer pain control but not so familiar with its intravenous administration."7.80Use of intravenous fentanyl against morphine tolerance in breakthrough cancer pain: a case series and literature review. ( Bruera, E; Hwang, IC; Park, SM, 2014)
"Utility functions based on fentanyl's experimental effects on respiration and pain relief were successfully constructed."7.79Fentanyl utility function: a risk-benefit composite of pain relief and breathing responses. ( Aarts, L; Boom, M; Dahan, A; Fussen, R; Groeneveld, GJ; Hay, J; Neukirchen, M; Olofsen, E; Sarton, E, 2013)
"Fentanyl pectin nasal spray is a novel intranasal formulation for the management of breakthrough cancer pain in patients taking and tolerant to opioids for persistent cancer pain."7.79Fentanyl pectin nasal spray: a novel intranasal delivery method for the treatment of breakthrough cancer pain. ( Bulloch, MN; Hutchison, AM, 2013)
") administration of the central analgesics fentanyl and dipyrone, and also mediators of pain such as L-glutamate, CCK, ATP, phenylephine and analgesic mediator adenosine, slightly penetrating in CNS, in the minimum effective dose (MED) cause the maximal analgesic effect in the tail flick test in rats."7.78[Peripheral acting mediators pain and analgesia potentiate the central analgesic action of fentanyl and dipyrone]. ( Gmiro, VE; Serdiuk, SE, 2012)
"Determining the appropriate dose of transdermal fentanyl (TDF) for the alleviation of cancer pain requires determining the factors causing variations in serum fentanyl concentration after TDF treatment."7.78Population pharmacokinetics of transdermal fentanyl in patients with cancer-related pain. ( Ebinuma, K; Kokubun, H; Matoba, M; Takayanagi, R; Yago, K; Yamada, Y, 2012)
"This study sought to prospectively assess fentanyl safety in a large out-of-hospital group, to identify variables associated with post-fentanyl hypotension (HN; systolic blood pressure [SBP] < 90) or hypoxemia (HX; SpO(2) < 90%)."7.77Fentanyl in the out-of-hospital setting: variables associated with hypotension and hypoxemia. ( Krauss, WC; Shah, S; Thomas, SH, 2011)
"This study analysed the analgesic effect and changes in vital signs associated with administration of inhaled Methoxyflurane (MTX) and/or intranasal Fentanyl (INF) for prehospital management of visceral pain."7.77Inhaled methoxyflurane and intranasal fentanyl for prehospital management of visceral pain in an Australian ambulance service. ( Brightwell, R; Johnston, S; Thompson, JA; Wilkes, GJ; Ziman, M, 2011)
"We experienced a patient with an ileal artificial anus who suffered from abdominal pain caused by peritoneal dissemination of ovarian cancer, for which slow-release oxycodone was ineffective, but fentanyl patch proved effective."7.77[A case of pain management using transdermal fentanyl patches for peritoneal carcinomatosis in a patient with small intestine stoma]. ( Iwazaki, M; Masuda, R; Mikami, M; Nishiumi, N; Saito, Y; Tokuda, Y; Yoshino, K, 2011)
" Compared with other opioids, low-dose fentanyl has been suggested to produce milder side effects such as nausea, constipation, and somnolence."7.77[Direct low-dose fentanyl patch (2.1mg) introduction for opioid naïve outpatients with cancer pain]. ( Fujita, S; Fukae, M; Hata, A; Iwamori, S; Kaji, R; Katakami, N; Masuda, Y; Mifune, Y; Nanjo, S; Orita, H; Otsuka, K; Yamatani, T, 2011)
"To identify predictive factors requiring high-dose transdermal fentanyl in opioid switching from oral morphine or oxycodone to transdermal fentanyl in patients with cancer pain."7.77Factors predicting requirement of high-dose transdermal fentanyl in opioid switching from oral morphine or oxycodone in patients with cancer pain. ( Fujimoto, S; Hosokawa, T; Kanbayashi, Y; Konishi, H; Miki, T; Okamoto, K; Otsuji, E; Takagi, T; Taniwaki, M; Yoshikawa, T, 2011)
"The three-cycle fentanyl patch system provided a stable plasma fentanyl concentration and excellent pain relief and should be considered for pain control in cancer patients."7.77Three-cycle fentanyl patch system contributes to stable control of plasma fentanyl concentration in gynecologic cancer pain patients. ( Kanamori, C; Kanamori, T; Kanzaki, H; Tanaka, Y, 2011)
"The FDA has approved a nasal spray formulation of fentanyl (Lazanda-Archimedes) for management of breakthrough pain in adult cancer patients who are already receiving and are tolerant to opioid therapy."7.77Fentanyl nasal spray (Lazanda) for pain. ( , 2011)
"The aim of this study is to investigate cancer patients' response and side effects associated with transdermal therapeutic fentanyl (TTS-F), whose pain was hardly controlled by nonweak/weak opioids in Taiwan."7.76The use of transdermal fentanyl in cancer pain--a compliance study of outpatients in Taiwan. ( Chen, YJ; Chiou, TJ; Hung, CJ; Liu, CY; Su, YC; Tang, Y; Tzeng, WF; Weng, YC, 2010)
" We treated a 50s female with pain and dyspnea from bone metastasis and lymphangitis carcinomatosa after surgery for NSCLC in whom the optimal dosages of transdermal fentanyl (Durotep Patch) were determined by titration with fentanyl injection, and oxycodone hydrochloride (OxyContin) in a short period."7.76[Successful management of a patient with pain and dyspnea from bone metastasis and lymphangitis carcinomatosa after surgery for non-small cell lung cancer (NSCLC) in whom optimal dosages of transdermal fentanyl were determined by titration with fentanyl i ( Eguchi, K; Gika, M; Inoue, Y; Izawa, N; Nakayama, M; Takeuchi, K, 2010)
"For 20 hospitalized patients with cancer pain that could not be controlled by NSAIDs, the fentanyl transdermal patch (1."7.76Evaluation of analgesic effect and safety of fentanyl transdermal patch for cancer pain as the first line. ( Hoya, Y; Okamoto, T; Yanaga, K, 2010)
" Here, by using a chronic inflammation model, namely subplantar injection of Complete Freund's adjuvant, we show a peripheral synergistic interaction between the histamine H(3) receptor agonist R-(alpha)-methylhistamine and fentanyl on the inhibition of thermal hyperalgesia and of peripheral substance P accumulation."7.76Histamine H3 receptor activation potentiates peripheral opioid-mediated antinociception: substance P role in peripheral inflammation in mice. ( Ciruela, F; Fernández-Dueñas, V; Gandía, J; Planas, E; Poveda, R; Sánchez, S, 2010)
"We describe here a patient who obtained a good analgesic effect with high-dose fentanyl patches for controlling cancer pain."7.76High-dose fentanyl patch for cancer pain of a patient with cholangiocarcinoma. ( Jang, HJ; Jung, JY; Kim, HS; Kim, JH; Kim, M; Shin, YC; Sung, CW, 2010)
" IV fentanyl PCA was used for pain control in 16 patients with lower extremity, neuropathic/ischaemic pain, scheduled for major lower extremity amputation."7.76Case report. Intravenous fentanyl patient-controlled analgesia for perioperative treatment of neuropathic/ischaemic pain in haemodialysis patients: a case series. ( Aretha, D; Filos, KS; Karanikolas, M; Kiekkas, P; Monantera, G; Tsolakis, I, 2010)
"Factors that influenced the choice of dose of oral transmucosal fentanyl at the time of burns dressing change were investigated in a prospective study."7.75Factors in the choice of oral transmucosal fentanyl citrate dose for adult burns dressings. ( Hanafiah, Z; Holdcroft, A; Shah, H; Smythe, J; Williams, GJ, 2009)
" The following data points were collected before and after each naloxone dose; blood pressure, heart rate, respiratory rate, RASS score, pain assessment score (recorded as present or absent), midazolam dose, propofol dose and fentanyl dose."7.75Safety of enteral naloxone for the reversal of opiate-induced constipation in the intensive care unit. ( Arpino, PA; Thompson, BT, 2009)
"This report describes an infant who was born to a mother with chronic pain treated with fentanyl 100 microg/h transdermal patch throughout her pregnancy and during lactation."7.75Fentanyl transdermal analgesia during pregnancy and lactation. ( Cohen, RS, 2009)
"Given preemptively, nefopam may be effective at improving postoperative pain management and at reducing the risk of developing postoperative chronic pain, because the drug has both analgesic and antihyperalgesic properties."7.75Long-term pain vulnerability after surgery in rats: prevention by nefopam, an analgesic with antihyperalgesic properties. ( Chateauraynaud, J; Laboureyras, E; Richebé, P; Simonnet, G, 2009)
"Morphine, oxycodone, and fentanyl are clinically prescribed drugs for the management of severe pain."7.75Morphine, oxycodone, and fentanyl exhibit different analgesic profiles in mouse pain models. ( Hasegawa, M; Ito, H; Kanemasa, T; Kato, A; Kihara, T; Koike, K; Masuno, K; Matsumoto, M; Matsushima, S; Minami, K; Miyoshi, T; Nakamura, A; Narita, M; Orita, S; Shimada, S; Suzuki, T; Tomii, T; Torii, M, 2009)
"The fentanyl transdermal matrix patch is approved in Japan for the management of moderate to severe cancer-related pain in adults."7.74Fentanyl transdermal matrix patch (Durotep MT patch; Durogesic DTrans; Durogesic SMAT): in adults with cancer-related pain. ( Hoy, SM; Keating, GM, 2008)
"To evaluate the efficacy and safety of fentanyl administered by PCA in children with cancer pain."7.74Safety and efficacy of fentanyl administered by patient controlled analgesia in children with cancer pain. ( Barone, G; Chiaretti, A; Lazzareschi, I; Liotti, L; Riccardi, R; Ruggiero, A, 2007)
" The median VAS scores of all patients were above 4 (moderate to severe pain) before the administration of transdermal fentanyl."7.74[Transdermal fentanyl in treating severe painful mucositis caused by autologous hematopoietic stem cell transplantation]. ( Bu, Q; Cai, QQ; Gao, Y; Huang, HQ; Lin, XB; Peng, YL; Wang, BF, 2007)
"The implementation of a fentanyl-based pain management protocol resulted in a marked reduction in time to initial analgesia among trauma patients."7.74A fentanyl-based pain management protocol provides early analgesia for adult trauma patients. ( Curtis, KM; Fanciullo, G; Henriques, HF; Reynolds, CM; Suber, F, 2007)
" Here we show that rats with chronic morphine treatment do not develop signs of tolerance at peripheral mu-opioid receptors (micro-receptors) in the presence of painful CFA-induced paw inflammation."7.74Chronic morphine use does not induce peripheral tolerance in a rat model of inflammatory pain. ( Binder, W; Brack, A; Fischer, O; Mousa, SA; Rittner, HL; Schäfer, M; Shakibaei, M; Shaqura, M; Stein, C; Urban, F; Zöllner, C, 2008)
"This retrospective study identified patients with cancer and noncancer pain who had received > or =1 prescription for fentanyl TD or buprenorphine TD (the all-patients groups) from the German IMS Disease Analyzer-mediplus database, which contains all relevant data concerning drug prescriptions from 400 practices in Germany."7.73Equipotent doses of transdermal fentanyl and transdermal buprenorphine in patients with cancer and noncancer pain: results of a retrospective cohort study. ( Likar, R; Nautrup, BP; Sittl, R, 2005)
"The present study was conducted to evaluate the pain development and bone destruction during bone cancer growth in a murine model of bone cancer pain and to evaluate the analgesic efficacy of fentanyl, sufentanil, and morphine in this model."7.73Evaluation of pain-related behavior, bone destruction and effectiveness of fentanyl, sufentanil, and morphine in a murine model of cancer pain. ( El Mouedden, M; Meert, TF, 2005)
"The purpose of this study was to compare changes in dosages of transdermal (TD) fentanyl and TD buprenorphine in patients with cancer and non-cancer pain."7.73Changes in the prescribed daily doses of transdermal fentanyl and transdermal buprenorphine during treatment of patients with cancer and noncancer pain in Germany: results of a retrospective cohort study. ( Nautrup, BP; Nuijten, M; Sittl, R, 2005)
"The current study was performed to evaluate the effectiveness and safety of transdermal therapeutic system (TTS) fentanyl in the management of acute pain due to oral mucositis in patients receiving stem cell transplantation."7.73Effectiveness of transdermal fentanyl patch for treatment of acute pain due to oral mucositis in patients receiving stem cell transplantation. ( Bae, NY; Baek, JH; Chae, YS; Kim, DH; Kim, JG; Kim, SY; Lee, KB; Sohn, SK, 2005)
" Data from patients with noncancer or cancer pain treated with TD buprenorphine or TD fentanyl for at least 3 months between May 2002 and April 2005 were analyzed."7.73Patterns of dosage changes with transdermal buprenorphine and transdermal fentanyl for the treatment of noncancer and cancer pain: a retrospective data analysis in Germany. ( Nuijten, M; Poulsen Nautrup, B; Sittl, R, 2006)
"The present study was undertaken to investigate the possible change in anti-hyperalgesic effect following repeated treatment with morphine or fentanyl using the dose to improve the thermal hyperalgesia under an inflammatory pain-like state."7.73Differences in tolerance to anti-hyperalgesic effects between chronic treatment with morphine and fentanyl under a state of pain. ( Hareyama, N; Hashimoto, S; Imai, S; Miyoshi, K; Nakamura, A; Narita, M; Nozaki, H; Suzuki, M; Suzuki, T; Takagi, T, 2006)
"The delayed effects (12-16 hours) of transdermal fentanyl make dose titration difficult during acute exacerbations of cancer pain."7.72A safe and effective method for converting patients from transdermal to intravenous fentanyl for the treatment of acute cancer-related pain. ( Kornick, CA; Manfredi, PL; O'Brien, PC; Payne, R; Santiago-Palma, J; Schulman, G; Weigand, S, 2003)
"A Markov model was constructed to simulate the resource use and health outcomes of one year of treatment comparing the fentanyl transdermal therapeutic system (fentanyl-TTS) with oral sustained-release (SR) morphine in outpatients with noncancer pain in Denmark."7.72A one year health economic model comparing transdermal fentanyl with sustained-release morphine in the treatment of chronic noncancer pain. ( Andersen, S; Frei, A; Hole, P; Jensen, NH, 2003)
"To evaluate driving performance, cognition, and balance in patients with chronic nonmalignant pain before and after the addition of transdermal fentanyl to their treatments."7.72The effects of transdermal fentanyl on driving, cognitive performance, and balance in patients with chronic nonmalignant pain conditions. ( Besser, M; Crerand, C; Frank, ED; Jalali, S; Menefee, LA; Park, J; Sanschagrin, K, 2004)
"The authors previously reported changes in electroencephalographic bicoherence during isoflurane anesthesia combined with epidural anesthesia."7.72Electroencephalographic bicoherence is sensitive to noxious stimuli during isoflurane or sevoflurane anesthesia. ( Hagihira, S; Mashimo, T; Mori, T; Takashina, M; Ueyama, H, 2004)
"To assess the analgesic safety and efficacy of Transdermal Therapeutic System (TTS)-fentanyl in the treatment of chronic gynecological cancer-related pain."7.72Evaluation of safety and efficacy of transdermal therapeutic system-fentanyl in adult patients with gynecological cancer-related pain. ( Cheewakriangkrai, C; Katanyoo, K; Lorvidhaya, V; Srisomboon, J; Suprapaphorn, P, 2004)
"(1) Some cancer patients suffer occasional breakthrough pain despite well-conducted opiate treatment, warranting the use of immediate-release oral morphine."7.71Oral transmucosal fentanyl: new preparation. For breakthrough cancer pain when morphine fails. ( , 2002)
"The role of the supraspinal endogenous opioid system in pain processing has been investigated in this study using positron emission tomography imaging of [11C]-carfentanil, a synthetic, highly specific mu opioid receptor (mu-OR) agonist."7.71Pain activation of human supraspinal opioid pathways as demonstrated by [11C]-carfentanil and positron emission tomography (PET). ( Bencherif, B; Campbell, JN; Dannals, RF; Frost, JJ; Fuchs, PN; Sheth, R, 2002)
"Early and significant reduction in pain (compared to baseline assessments) was achieved in children using intranasal fentanyl by 10 min and sustained throughout the 30 min of observations."7.71Intranasal fentanyl reduces acute pain in children in the emergency department: a safety and efficacy study. ( Borland, ML; Geelhoed, G; Jacobs, I, 2002)
"This open compassionate-use prospective registration study evaluated the tolerability, ease of use and applied doses of transdermal (TTS) fentanyl in adult patients with cancer-related pain requiring strong opioid analgesia."7.71Longitudinal follow-up of TTS-fentanyl use in patients with cancer-related pain: results of a compassionate-use study with special focus on elderly patients. ( Desmedt, M; Lossignol, D; Menten, J; Mullie, A, 2002)
"This prospective, open-label, before-after trial was designed to compare the efficacy of oral opioids with that of transdermal fentanyl in severe AIDS-related chronic pain, as well as assess barriers, patient satisfaction, and side effects."7.71Transdermal fentanyl for chronic pain in AIDS: a pilot study. ( Lefkowitz, M; Newshan, G, 2001)
"The fentanyl transdermal system (Duragesic) is an opioid analgesic indicated for the management of chronic moderate to severe pain."7.71Economic evaluation of the fentanyl transdermal system for the treatment of chronic moderate to severe pain. ( Bell, TJ; Dodd, SL; Neighbors, DM; Wilson, J, 2001)
"An expert working group of the European Association for Palliative Care has revised and updated its guidelines on the use of morphine in the management of cancer pain."7.71Morphine and alternative opioids in cancer pain: the EAPC recommendations. ( Casas, JR; Cherny, N; Conno, F; Hanks, GW; Hanna, M; Kalso, E; McQuay, HJ; Mercadante, S; Meynadier, J; Poulain, P; Radbruch, L; Ripamonti, C; Sawe, J; Twycross, RG; Ventafridda, V, 2001)
"This multicentre, observational study examined the efficacy of the therapeutic transdermal fentanyl system (TTS-fentanyl) in children requiring opioids for pain in life-threatening disease."7.71Transdermal fentanyl for pain relief in a paediatric palliative care population. ( Devine, T; Goldman, A; Hunt, A; Phillips, M, 2001)
"Continuous fentanyl infusion should be considered for the treatment of cancer pain in patients requiring high doses who become refractory to other opioids, when other opioids cause intolerable adverse effects, when patients have a true morphine allergy, or when high-dose requirements threaten to deplete existing stock of alternate opioids."7.70Continuous fentanyl infusion: use in severe cancer pain. ( Dunlap, DS; Lenz, KL, 1998)
"A transdermal fentanyl patch for the treatment of chronic cancer-related pain is available in four dosages (25, 50, 75, and 100 microg/hr)."7.70Factors influencing quality of life in cancer patients: the role of transdermal fentanyl in the management of pain. ( Payne, R, 1998)
"To study use of Duragesic (fentanyl transdermal system), the only transdermal opioid approved in Canada for treating chronic cancer pain in adults."7.69Fentanyl transdermal system. Pain management at home. ( Hays, H; Woodroffe, MA, 1997)
"A 62-year-old man receiving subcutaneous fentanyl for the management of cancer pain developed generalized central excitation after an overdose of 5000 micrograms of fentanyl."7.69Acute neuropsychiatric findings in a patient receiving fentanyl for cancer pain. ( Bruera, E; Pereira, J, 1997)
"To report a case of high transdermal fentanyl dosage requirements in a patient with chronic cancer pain."7.68High transdermal fentanyl requirements in a patient with chronic cancer pain. ( Lehr, VT; Renaud, EA, 1993)
"These results suggest that steady-state serum concentrations are approached by the second dose of TTS(fentanyl) and that the kinetics are stable with repeated dosing."7.68Transdermal fentanyl for cancer pain. Repeated dose pharmacokinetics. ( Foley, KM; Gupta, SK; Inturrisi, CE; Lapin, J; Layman, M; Portenoy, RK; Southam, MA, 1993)
"The author studied the use of intravenous Propofol for the relief of pain."7.68[Changes in the pain produced by the peripheral venous injection of propofol when it is combined with lidocaine or fentanyl]. ( Croston, J; de Henriquez, L; de Jiménez, L; Espinosa, V, 1992)
"Perineal pain during the course of routine epidural analgesia with bupivacaine was treated with a 10-ml top-up of either bupivacaine 25 mg, fentanyl 100 micrograms or fentanyl 100 micrograms plus bupivacaine 10 mg, in 46 women in the first stage of labour."7.67Epidural fentanyl and perineal pain in labour. ( O'Sullivan, G; Reynolds, F, 1989)
"Five cancer patients experienced satisfactory pain relief for periods of 3-156 days using continuous transdermal delivery of the narcotic fentanyl."7.67Transdermal fentanyl for pain control in patients with cancer. ( Dothage, JA; Miser, AW; Miser, JS; Narang, PK; Sindelar, W; Young, RC, 1989)
"To investigate the selective role of intraspinal opioids on the perception and modulation of pain, seven subjects with chronic hip or back pain and one subject with C-6 quadriplegia received 25 micrograms of intrathecal fentanyl."7.67Intrathecal fentanyl depresses nociceptive flexion reflexes in patients with chronic pain. ( Chabal, C; Jacobson, L; Little, J, 1989)
"1 micrograms/kg fentanyl in low back pain patients reduced both sensory intensity and unpleasantness visual analogue scale (VAS) responses to experimental pain evoked by graded 5-sec nociceptive temperature stimuli (45-51 degrees C) as well as VAS-sensory and VAS-affective responses to clinical pain."7.67A simultaneous comparison of fentanyl's analgesic effects on experimental and clinical pain. ( Harkins, SW; Price, C; Price, DD; Rafii, A, 1986)
"The effect of thyrotropin releasing hormone (TRH) on modified neuroleptanesthesia with fentanyl-flunitrazepam was investigated in an open pilot study of 15 neurosurgical patients."7.67Failure of thyrotropin releasing hormone to reverse fentanyl-flunitrazepam anesthesia in man. ( Dangelmaier, R; Glöser, A; Hempel, V; Lenz, G, 1986)
"Patients with renal lithiasis were included and were randomized to Group A (basal analgesia: midazolam (1 mg), fentanyl (0."7.11Value of Music and Nitrous Oxide for Pain Control during Extracorporeal Shock Wave Lithotripsy (ESWL). ( Alcoba-García, MP; Bueno-Serrano, G; González-Enguita, C; González-López, R; Llanos-Jiménez, L; Mahillo-Fernández, I; Tabares-Jiménez, J, 2022)
"Severe pain is defined as rated seven or greater on a 0 to 10 age-appropriate numeric pain scale or equivalent."6.77Intranasal fentanyl versus intravenous morphine in the emergency department treatment of severe painful sickle cell crises in children: study protocol for a randomised controlled trial. ( an Fhailí, S; Barrett, MJ; Cronin, J; Grant, T; Hayden, J; McCoy, S; McMahon, C; Murphy, A; O'Sullivan, R; Wakai, A; Walsh, S, 2012)
"Patients with chronic cancer pain were randomly assigned to the conversion from continuous intravenous infusion to transdermal fentanyl using two-step taper of the continuous intravenous infusion in 12 h (12-h method) or the conversion in 6 h (6-h method)."6.76Six- versus 12-h conversion method from intravenous to transdermal fentanyl in chronic cancer pain: a randomized study. ( Hayashi, K; Kamata, M; Kojima, H; Kozai, M; Nomura, M; Sawada, S, 2011)
"Of 139 recruited patients, 69% identified an effective dose of sublingual fentanyl ODT (a dosage that successfully treated all episodes of BTcP over two consecutive days) and entered the maintenance phase, during which they were treated for a median of 149."6.76Long-term effectiveness and tolerability of sublingual fentanyl orally disintegrating tablet for the treatment of breakthrough cancer pain. ( Derrick, R; Dumble, S; Hassman, D; Howell, J; Nalamachu, S; Wallace, MS, 2011)
" Adverse events were also recorded."6.76The efficacy and safety of fentanyl buccal tablet compared with immediate-release oxycodone for the management of breakthrough pain in opioid-tolerant patients with chronic pain. ( Ashburn, MA; Messina, J; Slevin, KA; Xie, F, 2011)
" Adverse events were recorded throughout."6.76Sublingual fentanyl orally disintegrating tablet in daily practice: efficacy, safety and tolerability in patients with breakthrough cancer pain. ( Müller-Schwefe, GH; Überall, MA, 2011)
"During maintenance treatment, 70 of 646 patients (11%) discontinued because of adverse events (AEs), 69 of 646 (11%) because of withdrawn consent, and 57 of 646 (9%) because of noncompliance."6.75Long-term safety and tolerability of fentanyl buccal tablet for the treatment of breakthrough pain in opioid-tolerant patients with chronic pain: an 18-month study. ( Fine, PG; Messina, J; Rathmell, J; Xie, F, 2010)
"Fentanyl is an opioid with high lipid solubility, suitable for intravenous, spinal, transmucosal and transdermal administration."6.74Transdermal fentanyl in cachectic cancer patients. ( Gergov, M; Haakana, S; Heiskanen, T; Kalso, E; Mätzke, S; Vuori, E, 2009)
"Breakthrough cancer pain (BTcP) represents an important clinical challenge in the care of patients with cancer."6.74Efficacy and long-term tolerability of sublingual fentanyl orally disintegrating tablet in the treatment of breakthrough cancer pain. ( Bartkowiak, AJ; Derrick, R; Hassman, D; Hayes, TG; Howell, J; Nalamachu, S; Rauck, RL; Reyes, E; Tark, M, 2009)
" Any adverse events were recorded; four tolerability endpoints, constipation, nausea, daytime drowsiness, and sleeping disturbances, were assessed daily."6.73A randomized, open, parallel group, multicenter trial to investigate analgesic efficacy and safety of a new transdermal fentanyl patch compared to standard opioid treatment in cancer pain. ( Heiskanen, T; Hoerauf, KH; Jensen, NH; Krenn, H; Kress, HG; Lundorff, L; Nolte, T; Petersen, R; Rosland, JH; Sabatowski, R; Saedder, EA; Von der Laage, D, 2008)
"2% of patients experienced adverse events that were either probably related or very likely to be related to the study drug."6.73Safety and efficacy of transdermal fentanyl in patients with cancer pain: phase IV, Turkish oncology group trial. ( Aliustaoğlu, M; Altinbaş, M; Altundağ, K; Atahan, L; Cooper, R; Demirkan, B; Kömürcü, S; Manavoğlu, O; Ozdemir, F; Ozkök, S; Pak, Y; Sarihan, S; Turhal, S; Turna, HS; Yavuz, AA; Yaylaci, M, 2007)
"In episodes treated with IV-MO, pain intensity decreased from a mean of 6."6.73Transmucosal fentanyl vs intravenous morphine in doses proportional to basal opioid regimen for episodic-breakthrough pain. ( Casuccio, A; Ferrera, P; Intravaia, G; Mangione, S; Mercadante, S; Villari, P, 2007)
" Pain intensity (PI) (rated on an 11-point pain scale, from 0 = no pain to 10 = worst pain) and other outcomes were assessed before dosing and for 2 hours after dosing."6.73Fentanyl buccal tablet for the relief of breakthrough pain in opioid-tolerant adult patients with chronic neuropathic pain: a multicenter, randomized, double-blind, placebo-controlled study. ( Hale, M; Messina, J; Simpson, DM; Xie, F, 2007)
"Although common treatments for osteoarthritis (OA) pain, such as nonsteroidal antiinflammatory drugs (NSAIDs), simple analgesics, and weak opioids, provide relief in some cases, they fail to control pain or are poorly tolerated in many cases."6.72Transdermal fentanyl for improvement of pain and functioning in osteoarthritis: a randomized, placebo-controlled trial. ( Langford, R; McKenna, F; Ratcliffe, S; Richarz, U; Vojtassák, J, 2006)
" The magnitude of analgesia in the cold pressor model showed some correlation with TDF dosage and comparable effects for the full agonist fentanyl and the partial agonist buprenorphine."6.72Differential sensitivity of three experimental pain models in detecting the analgesic effects of transdermal fentanyl and buprenorphine. ( Gasser, UE; Koltzenburg, M; Pokorny, R; Richarz, U, 2006)
"Fentanyl is a synthetic opioid that can be delivered through a transdermal therapeutic system (TTS)."6.71Transdermal fentanyl in HSCT patients: an open trial using transdermal fentanyl for the treatment of oral mucositis pain. ( Carrassi, A; Deliliers, GL; Demarosi, F; Lodi, G; Sardella, A; Soligo, D; Volpe, AD, 2004)
"Remifentanil is a short acting, potent synthetic opioid that does not accumulate after infusion or repeated bolus doses."6.71Remifentanil vs fentanyl/morphine for pain and stress control during pediatric cardiac surgery. ( Arana, A; Bell, G; Dickson, U; Marshall, C; Morton, N; Robinson, D, 2004)
" Pharmacokinetic parameters were calculated by noncompartment analysis."6.71Pharmacokinetics and tolerability of different doses of fentanyl following sublingual administration of a rapidly dissolving tablet to cancer patients: a new approach to treatment of incident pain. ( Bredenberg, S; Hedner, T; Holmberg, M; Lennernäs, B; Lennernäs, H; Nyström, C, 2005)
" In groups 6 and 7, additional fentanyl doses were lower than in the other groups, but only in group 7 was the total fentanyl dosage low."6.71Effectiveness of eutectic mixture of local anesthetic cream and occlusive dressing with low dosage of fentanyl for pain control during shockwave lithotripsy. ( Basar, H; Basar, MM; Batislam, E; Ozcan, S; Tuglu, D; Yilmaz, E, 2005)
" Large patient-to-patient variations in pharmacokinetic parameters occurred, although intraindividual variability was limited."6.71Inter- and intraindividual variabilities in pharmacokinetics of fentanyl after repeated 72-hour transdermal applications in cancer pain patients. ( Bressolle, F; Caumette, L; Culine, S; Garcia, F; Pinguet, F; Poujol, S; Solassol, I, 2005)
"We used infantile neuronal ceroid lipofuscinosis (INCL), in which deterioration of the central nervous system is extremely rapid, to study constant release of an opioid for pains of central origin in a metabolic disease."6.70Transdermal fentanyl therapy for pains in children with infantile neuronal ceroid lipofuscinosis. ( Heiskala, HJ; Mannerkoski, MK; Pouttu, JA; Santavuori, PR, 2001)
"The treatment of cancer pain with transdermal fentanyl can be performed as a long-term therapy and result in good pain relief."6.69Long-term treatment of cancer pain with transdermal fentanyl. ( Donner, B; Raber, M; Strumpf, M; Zenz, M, 1998)
"TTS fentanyl was titrated to pain relief, and patients were followed up for as long as 3 months."6.69A clinical evaluation of transdermal therapeutic system fentanyl for the treatment of cancer pain. ( Hays, H; Moulin, DE; Sloan, PA, 1998)
"To treat cancer pain, physicians often decide to jump directly from step 1 of the World Health Organization (WHO) analgesic ladder to step 3."6.69Transdermal fentanyl in opioid-naive cancer pain patients: an open trial using transdermal fentanyl for the treatment of chronic cancer pain in opioid-naive patients and a group using codeine. ( Mattern, C; Uitendaal, MP; Vielvoye-Kerkmeer, AP, 2000)
"Midazolam was found to be the drug of preference for the majority of patients."6.67Midazolam versus fentanyl as premedication for painful procedures in children with cancer. ( Conner, K; Dickson, N; Luzins, J; McGorray, S; Reilly, K; Sandler, ES; Weyman, C, 1992)
"Alfentanil was used as an adjuvant to midazolam for analgesia in thirty outpatients undergoing colonoscopy."6.67Pain relief for outpatient colonoscopy: a comparison of alfentanil with fentanyl. ( Holloway, AM; Logan, DA, 1990)
"His pain was scored as a five on a six-point visual analog scale, and it persisted despite routine supportive therapy."6.50[A case of Guillain-Barré syndrome with severe pain successfully controlled with acetaminophen, gabapentin, and parenterally infused fentanyl]. ( Anzai, S; Hashimoto, Y; Nagasawa, K; Suzuki, T, 2014)
"Fentanyl is a lipophilic, short-acting, synthetic opioid with a piperidine chemical structure."6.45The role of fentanyl in cancer-related pain. ( Prommer, E, 2009)
" FBT utilizes OraVescent technology to improve bioavailability and speed of drug delivery."6.44Fentanyl buccal tablet: faster rescue analgesia for breakthrough pain? ( Hanna, M; Lecybyl, R, 2007)
"Pain is experienced by most cancer patients and represents an important issue in the clinical setting."6.44Oral transmucosal fentanyl citrate in cancer pain management: a practical application of nanotechnology. ( Mystakidou, K; Tsiatas, M; Tsilika, E; Vlahos, L, 2007)
"The fentanyl buccal tablet is a new sugar-free, easily-administered formulation that uses an effervescent drug delivery system to enhance the rate and extent of fentanyl absorption across the buccal mucosa."6.44Fentanyl buccal tablet: rapid relief from breakthrough pain. ( Taylor, DR, 2007)
"Persistent pain is present to some degree throughout the day and primarily is controlled with around-the-clock medication."6.42Managing breakthrough pain: a clinical review with three case studies using oral transmucosal fentanyl citrate. ( Palos, G; Rhiner, M; Termini, M, 2004)
" However, clinicians should realize that the manufacturer's recommendations for equianalgesic dosing of transdermal fentanyl may result in initial doses that are too low in some patients, and in a titration period that is too long."6.41An alternative algorithm for dosing transdermal fentanyl for cancer-related pain. ( Breitbart, W; Chandler, S; Eagel, B; Ellison, N; Enck, RE; Lefkowitz, M; Payne, R, 2000)
" The dosing interval for these systems is generally 3 days."6.41Treatment of cancer pain with transdermal fentanyl. ( Gourlay, GK, 2001)
"Fentanyl is a synthetic opioid with short-acting analgesic activity after intravenous or subcutaneous administration."6.40Transdermal fentanyl. A review of its pharmacological properties and therapeutic efficacy in pain control. ( Benfield, P; Jeal, W, 1997)
"Alfentanil may cause less intense respiratory depression than equianalgesic doses of fentanyl."6.37Alfentanil in anesthesia and analgesia. ( Reitz, JA, 1986)
"The control group listened to the natural environment and received Fentanyl for pain relief, and the interventional group listened to the Qur'an recitation and received Fentanyl for pain relief."5.69The Effects of Listening to the Qur'an in the Postoperative Management of the Patients Undergoing Laparoscopic Cholecystectomy in the Day Surgery Unit. ( Abdullah, KL; Ahmad, CA; Atkins, L; Devol, EB; Hussain, A; Maarof, SR, 2023)
"The addition of gabapentin to moderate sedation during D&E did not result in lower maximum recalled procedural pain."5.69Gabapentin as an adjunct for pain management during dilation and evacuation: A double-blind randomized controlled trial. ( Brant, AR; Floyd, S; Lotke, PS; Reeves, MF; Scott, RK; Tefera, E; Ye, PP, 2023)
" The number of analgesic pump compressions and pain scores at all 4 time points and fentanyl consumption at 48 hours after surgery were significantly lower in the electroacupuncture treatment groups than in the sham electroacupuncture group (P<."5.69Efficacy of electroacupuncture combined with intravenous patient-controlled analgesia after cesarean delivery: a randomized clinical trial. ( Feng, Y; Hu, S; Jin, Y; Li, Y; Liu, L; Wang, B; Wang, L; Xiong, B; Yu, X, 2023)
"IV Lidocaine did not meet the criteria for non-inferiority with lower prehospital pain reduction than fentanyl but was safe and better tolerated as analgesia in ST-elevation myocardial infarction (STEMI)."5.69LidocAine Versus Opioids In MyocarDial infarction: the AVOID-2 randomized controlled trial. ( Andrew, E; Bernard, S; Brennan, A; Dinh, D; Fernando, H; Lefkovits, J; Milne, C; Myles, PS; Nehme, Z; O'Brien, J; Peter, K; Smith, K; Stephenson, M; Stub, D; Taylor, AJ, 2023)
"This study aimed to compare the efficacy of intravenous, intranasal fentanyl and oral sucrose in reducing the pain response during retinopathy of prematurity examinations using premature infant pain profile (PIPP) scores."5.69Effects of fentanyl and sucrose on pain in retinopathy examinations with pain scale, near-infrared spectroscopy, and ultrasonography: a randomized trial. ( Arman, D; Cömert, S; Gül, A; Kara, N; Seymen, Z, 2023)
"Analgesia, Fentanyl, Lidocaine spray, Pain, Rib fracture, Tramadol."5.69Comparison of the Analgesic Efficacy of Lidocaine Spray versus Tramadol and Fentanyl for Pain Control in Rib Fractures. ( Donmez, S; Erdem, AB; Sener, A, 2023)
"Our aim was to evaluate pain reduction provided by intranasal fentanyl (INF) compared with placebo in addition to ibuprofen."5.69Additive Value of Intranasal Fentanyl on Ibuprofen for Pain Management of Children With Moderate to Severe Headaches: A Randomized Controlled Trial. ( Bailey, B; Boutin, A; Gouin, S; Gravel, J; Lebel, D, 2023)
" The time to extubation, respiratory complications, nausea, pain, and the number of patients receiving fentanyl were comparable between the groups."5.69The Impact of Head Elevation on Prevalence and Severity of Emergence Cough in Male Patients during Endotracheal Extubation. ( Kim, JE; Kim, JH; Lim, GM; Park, SJ; Park, SY, 2023)
"In contrast, withdrawal associated thermal hyperalgesia was found only in mice."5.62Divergent profiles of fentanyl withdrawal and associated pain in mice and rats. ( Arakawa, K; Cramer, N; Fox, ME; Jenne, C; Keller, A; Uddin, O, 2021)
"Cancer pain was observed in 131 of 160 patients with advanced cancer living at home."5.56[Analysis of Symptoms Relieved in Addition to Pain after Administration of Oxycodone or Morphine to Patients with Advanced Cancer Living at Home]. ( Watanabe, K, 2020)
" Complications including apnea, hypotension, hypoxia, nausea, and vomiting, along with gastroenterologist satisfaction and patients' pain score (based on Wong-Baker faces pain assessment scale), were recorded by a checklist."5.51Comparing the Efficacy and Safety of Dexmedetomidine/Ketamine with Propofol/Fentanyl for Sedation in Colonoscopy Patients: A Doubleblinded Randomized Clinical Trial. ( Aghaali, M; Ahmadpour, S; Alemi, F; Aminnejad, R; Hormati, A; Hormati, M; Sabouri, SM; Saeidi, M; Shafiee, H, 2022)
"To compare pain and the need for the opioid fentanyl use associated with the administration of phenylephrine 1."5.51Pain control and reduction of opioid use associated with intracameral phenylephrine1.0%-ketorolac 0.3% administered during cataract surgery. ( Donnenfeld, ED; Mychajlyszyn, A; Mychajlyszyn, D; Stein, R, 2022)
"We tested the following hypothesis: The addition of intranasal fentanyl to the standard practice of local infiltration with lidocaine would provide better pain control than lidocaine alone for adult ED patients undergoing I&D."5.51A Randomized, Placebo-Controlled Study of Intranasal Fentanyl as an Analgesic Adjunct For Incision and Drainage of Abscess. ( Baer, J; Feliciano, C; Friedman, BW; Gupta, C; Latev, A; Sharpe, S, 2022)
"This study investigates the effects of COMTval158met gene polymorphism on maternal anxiety and pain during delivery and on the analgesic and anxiety efficacy of dexmedetomidine during delivery."5.51Comparative study of the efficacy of dexmedetomidine and fentanyl on anxiety and pain of parturients with different COMTva1158met genotypes. ( Feng, YJ; Han, J; Pu, CX; Tang, LJ; Zhang, Y, 2022)
"Intranasal fentanyl seems to be a safe and effective alternative to acetaminophen with hydrocodone in reducing pain and improving hydration status in children with painful infectious mouth lesions and poor oral intake."5.51Intranasal Fentanyl to Reduce Pain and Improve Oral Intake in the Management of Children With Painful Infectious Mouth Lesions. ( Chen, JG; Cramm, K; Florez, C; Papa, L; Ramirez, J; Ruffin, TB; Salinero, E, 2022)
"Fentanyl has a low molecular weight and is lipophilic making it suitable for transdermal administration."5.51Unusual case of transdermal fentanyl in cachexia. ( Harrison, S; Kay, S; Lam, D; Pickard, J, 2019)
"We used oxycodone hydrochloride to treat a sharp pain resulting from cataplectic cancer in the jejunal tube, but this provided only limited pain relief."5.42[Efficacy of a fentanyl citrate buccal tablet for esophageal cancer pain management in a patient unable to take oral medication]. ( Baba, H; Fujimura, Y; Nakahara, O; Ohshima, S, 2015)
"To investigate if intravenous fentanyl or intravenous ketamine can provide adequate analgesia in preterm infants undergoing laser photocoagulation for retinopathy of prematurity (ROP)."5.41'NOPAIN-ROP' trial: Intravenous fentanyl and intravenous ketamine for pain relief during laser photocoagulation for retinopathy of prematurity (ROP) in preterm infants: A randomised trial. ( Agarwal, R; Chandra, P; Deorari, A; Madathil, S; Sankar, MJ; Thomas, D; Thukral, A, 2021)
"  NMDA receptor antagonists versus no treatment, placebo, oral sweet solution, or non-pharmacological intervention One RCT evaluated using oral ketamine (10 mg/kg body weight) versus sugar syrup (66."5.41Non-opioid analgesics for procedural pain in neonates. ( Bruschettini, M; Persad, E; Pizarro, AB, 2023)
" Opioids may result in an increase in episodes of apnea compared to placebo (RR 3."5.41Opioids for procedural pain in neonates. ( Borys, F; Bruschettini, M; Kinoshita, M; Olsson, E, 2023)
" Opioids may result in an increase in episodes of apnea compared to placebo (RR 3."5.41Opioids for procedural pain in neonates. ( Borys, F; Bruschettini, M; Kinoshita, M; Olsson, E, 2023)
" Our review shows that: - There may be little or no difference in pain relief (single dose IN vs IV fentanyl MD 4 mm, 95% CI -8 to 16 at 30 min by 100 mm VAS; multiple doses IN vs IV fentanyl MD 0, 95%CI -0."5.41Intranasal analgesia for acute moderate to severe pain in children - a systematic review and meta-analysis. ( Austad, B; Iakovleva, E; Munblit, D; Pedersen, SA; Prescott, MG; Simpson, MR; Vallersnes, OM, 2023)
"The evidence is very uncertain about the effect of topical anesthetics (lidocaine) compared to no anesthesia on successful lumbar puncture on first attempt, the number of attempts per lumbar puncture, episodes of bradycardia, episodes of desaturation, and occurrence of apnea."5.41Pharmacological interventions for the management of pain and discomfort during lumbar puncture in newborn infants. ( Bruschettini, M; Hedayati, E; Olsson, E; Pessano, S; Romantsik, O, 2023)
"Inhaled methoxyflurane for acute pain relief has demonstrated an analgesic effect superior to placebo."5.41Determination of equi-analgesic doses of inhaled methoxyflurane versus intravenous fentanyl using the cold pressor test in volunteers: a randomised, double-blinded, placebo-controlled crossover study. ( Comelon, M; Draegni, T; Høiseth, LØ; Lenz, H; Rosseland, LA, 2021)
"This study aimed to compare analgesic efficacy of intranasal (IN) ketamine to IN fentanyl for moderate to severe pain in children in a pediatric emergency department."5.41Analgesic Efficacy of Intranasal Ketamine Versus Intranasal Fentanyl for Moderate to Severe Pain in Children: A Prospective, Randomized, Double-Blind Study. ( Brady, J; Chitnis, SS; Drapkin, J; Fromm, C; Kriss, S; Likourezos, A; Motov, S; Pushkar, I; Quinn, K; Yasavolian, M, 2021)
" Although intravenously administered morphine can readily provide rapid and effective prehospital analgesia, oral transmucosal fentanyl citrate (OTFC) is a safe alternative that does not require intravenous access."5.38Safety and efficacy of oral transmucosal fentanyl citrate for prehospital pain control on the battlefield. ( Fowler, M; Kotwal, RS; McGhee, L; McManus, JG; Pennardt, A; Talbot, TS; Wedmore, IS, 2012)
" First of all, once assessed that all drugs induced dose-related antinociceptive effects, they were mixed in fixed ratio (1:1) combinations and a synergistic drug-drug interaction was obtained in all circumstances."5.37Fentanyl-trazodone-paracetamol triple drug combination: multimodal analgesia in a mouse model of visceral pain. ( Ciruela, F; Fernández, A; Fernández-Dueñas, V; Planas, E; Poveda, R; Sánchez, S, 2011)
"Fentanyl is an opioid initially developed for parenteral administration."5.36Formulations of fentanyl for the management of pain. ( Grape, S; Lauer, S; Schug, BS; Schug, SA, 2010)
"Fentanyl patch is an alternative for children who cannot tolerate morphine."5.35Fentanyl patch for stable chronic pain in children: new indication. Used fentanyl patches should be handled with care. ( , 2008)
"The femur bone cancer pain model was developed by implanting mouse osteolytic tumor cells (NCTC 2472) into the intramedulla of the femur in C3H/HeN mice."5.35Oxycodone-induced analgesic effects in a bone cancer pain model in mice. ( Ito, H; Kato, A; Kihara, T; Matsumoto, M; Minami, K; Narita, M; Orita, S; Suzuki, T; Tomii, T, 2008)
"Pain was well controlled."5.35Fentanyl-induced neurotoxicity and paradoxic pain. ( George, ML; Okon, TR, 2008)
"We sought to evaluate the efficacy of using a quick response (QR) code within video education to guide proper use of fentanyl transdermal patches and control pain, depression, and anxiety levels in cancer patients."5.34Video Education Reduces Pain and Anxiety Levels in Cancer Patients Who First Use Fentanyl Transdermal Patch: A Randomized Controlled Trial. ( Chen, J; Hu, X; Mao, X; Rao, Y; Xuan, Z; Yang, S; Ye, Z; Zhang, Y, 2020)
"Fifty percent N2O strongly reduced hyperalgesia induced by a first inflammation and its enhancement by fentanyl, and prevented exaggerated hyperalgesia induced by second inflammatory pain or NNES."5.34Nitrous oxide (N2O) prevents latent pain sensitization and long-term anxiety-like behavior in pain and opioid-experienced rats. ( Bessière, B; Contarino, A; Laboureyras, E; Laulin, JP; Richebé, P; Simonnet, G, 2007)
" The bioavailability of fentanyl was statistically different according to patient age."5.33Inter- and intra-individual variability in transdermal fentanyl absorption in cancer pain patients. ( Astre, C; Bressolle, F; Caumette, L; Coulouma, R; Culine, S; Garcia, F; Pinguet, F; Solassol, I; Thézenas, S, 2005)
"Pain affects many cancer patients, and in advanced stages of the disease it can significantly affect the quality of their lives."5.33Three-cycle fentanyl patch system significantly improves pain control in gynecologic cancer. ( Hayashi, M; Kanamori, C; Kanamori, T; Kanzaki, H; Yorioka, H, 2006)
"Fentanyl is a synthetic, lipophilic opioid, more potent than morphine, and achieves peak effects after intravenous administration in 5 minutes."5.32Intravenous fentanyl for cancer pain: a "fast titration" protocol for the emergency room. ( Martins, M; Soares, LG; Uchoa, R, 2003)
"Morphine side effects were reduced in some patients who changed to transdermal fentanyl, but there was no reduction in those who needed high-dose morphine for rescue analgesia."5.32A study of transdermal fentanyl in cancer pain at Aichi-Cancer Center. ( Hasegawa, M; Hosoda, R; Kamiya, Y; Kato, K; Mizaki, T; Nitta, M; Yamazaki, S, 2004)
"Dextromethorphan produced lower ED(50) values for morphine, fentanyl and sufentanil but exerted no effect on the potency of SNC80 or U50,488H."5.31Dextromethorphan and ketamine potentiate the antinociceptive effects of mu- but not delta- or kappa-opioid agonists in a mouse model of acute pain. ( Baker, AK; Hoffmann, VL; Meert, TF, 2002)
"Most patients suffered from cancer pain and only 11 patients had chronic pain from non-malignant disease."5.31Transdermal fentanyl for the management of cancer pain: a survey of 1005 patients. ( Brunsch-Radbruch, A; Grond, S; Lehmann, KA; Petzke, F; Radbruch, L; Sabatowski, R, 2001)
"To determine whether intranasal ketamine is noninferior to intranasal fentanyl for pain reduction in children presenting with acute extremity injuries."5.30Effect of Intranasal Ketamine vs Fentanyl on Pain Reduction for Extremity Injuries in Children: The PRIME Randomized Clinical Trial. ( Caruso, M; Florin, TA; Frey, TM; Mittiga, MR; Zhang, N; Zhang, Y, 2019)
"Liberalising an intravenous fentanyl treatment protocol applied by ambulance personnel slightly increased the number of patients with sufficient pain relief at hospital arrival without compromising patient safety."5.30Prehospital intravenous fentanyl administered by ambulance personnel: a cluster-randomised comparison of two treatment protocols. ( Christensen, EF; Friesgaard, KD; Giebner, M; Kirkegaard, H; Nikolajsen, L; Rasmussen, CH, 2019)
"Morphine was approximately 7440 times less potent than dihydroetorphine while heroin and fentanyl were approximately 163."5.30Anti-allodynic actions of intravenous opioids in the nerve injured rat: potential utility of heroin and dihydroetorphine against neuropathic pain. ( Hairston, CT; Harris, LS; Lutz, PO; Martin, TJ; Porreca, F, 1998)
"To assess whether inhaled nitrous oxide is noninferior to intravenous (IV) sedation for pain control during outpatient surgical abortion between 12 and 16 weeks of gestation."5.27Nitrous Oxide Compared With Intravenous Sedation for Second-Trimester Abortion: A Randomized Controlled Trial. ( Espey, E; Pitotti, J; Sheeder, J; Singh, RH; Teal, S; Thaxton, L, 2018)
"The authors consider endotracheal narcosis with nitrous oxide combined with fractional injections of phentanyl and seduxen of phentanyl and droperidol to be a method of choice."5.26[Characteristics of combined nitrous oxide nacrosis and premedication with phentanyl and droperidol or phentanyl and seduxen in patients with pain syndrome caused by blood vessel diseases of the lower extremities]. ( Korzh, OB; Timchuk, ID, 1979)
" Propofol with opioids has been recommended for gastroscopy sedation but the effects on cough reflex suppression remain unclear."5.24Effect of propofol combined with opioids on cough reflex suppression in gastroscopy: study protocol for a double-blind randomized controlled trial. ( Cao, YZ; Lu, X; Xia, J; Xie, J; Yin, N; Yuan, J, 2017)
"The neurodevelopmental impact of fentanyl given to preterm newborns for pain control is still unknown."5.24Follow-up at the corrected age of 24 months of preterm newborns receiving continuous infusion of fentanyl for pain control during mechanical ventilation. ( Ancora, G; Faldella, G; Ferrari, F; Garetti, E; Lago, P; Merazzi, D; Pierantoni, L; Pirelli, A, 2017)
" Further research is required to determine whether the use of nitrous oxide has a role, and to develop a safe and effective analgesic strategy to fully ameliorate the pain of ROP screening."5.22Analgesia for retinopathy of prematurity screening: A systematic review. ( Hamilton, DL; Hassan, R; Savant, SV; Thirunavukarasu, AJ, 2022)
"To compare pain incidence and changes in pain scores with fentanyl versus placebo as pre-emptive treatment during turning and 30 min post-turning in mechanically ventilated critically ill patients."5.22Fentanyl as pre-emptive treatment of pain associated with turning mechanically ventilated patients: a randomized controlled feasibility study. ( Baños, JE; Castillo, A; Gich, I; Juanes-Borrego, E; Mancebo, J; Navarro, M; Nicolás-Arfelis, JM; Puntillo, K; Robleda, G; Roche-Campo, F; Rodríguez-Arias, A; Sendra, MÀ; Urrutia, G, 2016)
"A higher dose of fentanyl led to significantly decreased pain scores as measured by the numeric rating scale (0."5.22Does Fentanyl Lead to Opioid-induced Hyperalgesia in Healthy Volunteers?: A Double-blind, Randomized, Crossover Trial. ( Bandschapp, O; Dolder, P; Filitz, J; Mauermann, E; Rentsch, KM; Ruppen, W, 2016)
"To evaluate the efficacy of oral transmucosal fentanyl citrate (OTFC) in the treatment of dyspnea on exertion in patients with advanced cancer."5.20A randomized crossover clinical trial to evaluate the efficacy of oral transmucosal fentanyl citrate in the treatment of dyspnea on exertion in patients with advanced cancer. ( Bruera, E; Correas, MÁ; Moralo, MJ; Pinna, MÁ; Vargas, RM, 2015)
"To compare the effectiveness and safety of fentanyl with placebo as pre-emptive treatment for pain associated with turning in patients in intensive care units."5.20A randomized controlled trial of fentanyl in the pre-emptive treatment of pain associated with turning in patients under mechanical ventilation: research protocol. ( Baños, JE; Castillo, A; Gich, I; Juanes-Borrejo, E; Mancebo, J; Navarro, M; Robleda, G; Roche-Campo, F; Rodríguez-Arias, A; Sendra, MÀ; Urrútia, G, 2015)
"Transdermal fentanyl is an effective, convenient, and well-tolerated treatment for mucositis pain caused by chemoradiotherapy, which can improve ESCC patients' quality of life."5.20Efficacy and safety of transdermal fentanyl for the treatment of oral mucositis pain caused by chemoradiotherapy in patients with esophageal squamous cell carcinoma. ( Xing, SZ; Zhang, Y, 2015)
"To determine the differences by comparing fentanyl and ketamine used in cancer-diagnosed children undergoing painful procedures."5.20The clinical effect of fentanyl in comparison with ketamine in analgesic effect for oncology procedures in children: a randomized, double-blinded, crossover trial. ( Monsereenusorn, C; Rujkijyanont, P; Traivaree, C, 2015)
" Four interventions were used: a standardized time-specific VOE protocol; intranasal fentanyl as the first parenteral pain medication; an SCD pain medication calculator; and provider and patient/family education."5.20Improving the Management of Vaso-Occlusive Episodes in the Pediatric Emergency Department. ( Barry, K; Champigny, M; Dorfman, D; Kavanagh, PL; Killius, K; Miner, R; Moses, JM; Sobota, A; Sprinz, PG; Wolfgang, TL, 2015)
"The aim of this study is to investigate the effects of propofol alone, propofol + remifentanil, and propofol + fentanyl combinations on the total dose of propofol to be administered during ERCP and on the pain scores after the process."5.20Comparison of Propofol, Propofol-Remifentanil, and Propofol-Fentanyl Administrations with Each Other Used for the Sedation of Patients to Undergo ERCP. ( Aydınlı, B; Bozkurt, E; Demir, B; Dişibeyaz, S; Haytural, C; Kazancı, D; Özgök, A; Parlak, E; Saraç, A, 2015)
"The sedative effects of dexmedetomidine in the ICU patients treated with ventilator bundle treatment are satisfactory, and it can shorten the duration of mechanical ventilation, extubation time and length of ICU stay, reduce the incidence of delirium."5.20[A study of using dexmedetomidine in ventilator bundle treatment in an ICU]. ( Dong, C; Li, J; Song, R; Yang, J, 2015)
"Managing cancer pain often requires opioid medications, such as fentanyl, which is frequently initiated parenterally, and then converted to transdermal form."5.19Efficacy and safety of a six-hour continuous overlap method for converting intravenous to transdermal fentanyl in cancer pain. ( Bloise, R; Davis, MP; Samala, RV, 2014)
"This study used a 60-s venous occlusion technique to evaluate the effectiveness of pretreatment with lidocaine, fentanyl, or remifentanil in preventing pain-induced withdrawal caused by intravenous injection of rocuronium bromide during the induction of general anesthesia."5.19Pretreatment with remifentanil, fentanyl, or lidocaine to prevent withdrawal after rocuronium using venous occlusion technique in children and adolescents: a prospective randomized placebo-controlled double-blind study. ( Abu-Halaweh, AS; Abu-Halaweh, SA; Al Zaben, KR; Al-Hussami, MO; Aloweidi, AK; Qudaisat, IY, 2014)
"Furthermore, in patients where a shift to a fentanyl patch was possible, good long-term pain control was achieved."5.19[Opioid induction using rapid release drugs and the shift to fentanyl patches]. ( Ejima, M; Morohashi, T; Nakayama, H; Otsuka, Y; Sasaki, S; Suzuki, N; Terai, E; Tsujikawa, Y; Watanabe, T; Yoshimura, K, 2014)
"To evaluate the pain on injection of propofol via different combinations of fentanyl, sufentanil or remifentanil in gastrointestinal endoscopy."5.19Comparing the pain of propofol via different combinations of fentanyl, sufentanil or remifentanil in gastrointestinal endoscopy. ( Bao, Y; Shi, D; Zhang, L, 2014)
"Fentanyl injection of small dose at auricular points achieves definite analgesic effect on procedural pain in dressing changes of burn wounds, superior to subcutaneous injection of fentanyl."5.19[Prevention of procedural pain in dressing changes of burn wounds by auricular injection of small-dose fentanyl]. ( Liu, B; Liu, YF; Su, XJ; Zhang, SH; Zhu, HX, 2014)
"Sublingual fentanyl proved inadequate in relieving pain during BMAB as no significant differences in the pain scores of the fentanyl and placebo patients were observed."5.17Pre-medication with sublingual fentanyl did not relieve pain associated with bone marrow aspiration and biopsy: a randomized feasibility trial. ( Ebeling, F; Kuivalainen, AM; Rosenberg, PH, 2013)
"Twenty-two healthy males were included in a randomized study to assess the changes in EPs after 110 sweeps of painful electrical stimulation to the median nerve following treatment with buprenorphine, fentanyl or placebo patches."5.17A novel approach to pharmaco-EEG for investigating analgesics: assessment of spectral indices in single-sweep evoked brain potentials. ( Andresen, T; Arendt-Nielsen, T; Drewes, AM; Gram, M; Graversen, C; Mørch, CD; Nielsen, AK, 2013)
"In very preterm infants on mechanical ventilation, continuous fentanyl infusion plus open-label boluses of fentanyl does not reduce prolonged pain, but does reduce acute pain and increase side effects compared with open-label boluses of fentanyl alone."5.17Efficacy and safety of continuous infusion of fentanyl for pain control in preterm newborns on mechanical ventilation. ( Ancora, G; Faldella, G; Garetti, E; Lago, P; Mastrocola, M; Merazzi, D; Pierantoni, L; Pirelli, A, 2013)
"The study aimed to evaluate the effects of the pretreatment with lidocaine, fentanyl, and remifentanil using a venous occlusion technique in preventing pain caused by intravenous injection of rocuronium during induction of general anesthesia."5.17Comparison of three methods of preventing rocuronium induced pain on injection using venous occlusion technique: a randomized prospective double blind controlled study. ( Abu-Halaweh, NS; Abu-Halaweh, SA; Al-Hussami, MO; Al-Mustafa, M; Aloweidi, AK; Atyat, BS; Qudaisat, IY, 2013)
"The addition of fentanyl 1 mcg/kg to propofol for brief painful procedures reduces movement, propofol dose, and recovery time."5.17Prospective randomized crossover evaluation of three anesthetic regimens for painful procedures in children with cancer. ( Anghelescu, DL; Burgoyne, LL; Faughnan, LG; Hankins, GM; Pui, CH; Smeltzer, MP, 2013)
"Patients with bone-cancer pain, already on opioids, obtain clinically important, additional pain-control, with regular oxycodone/paracetamol dosing."5.16Efficacy of oxycodone/paracetamol for patients with bone-cancer pain: a multicenter, randomized, double-blinded, placebo-controlled trial. ( Fang, WX; Li, F; Sima, L; Wu, XM, 2012)
"The opioids buprenorphine and fentanyl significantly potentiate the effect of descending pain inhibition in healthy volunteers."5.16A double-blind, placebo-controlled study on the effect of buprenorphine and fentanyl on descending pain modulation: a human experimental study. ( Andresen, T; Arendt-Nielsen, L; Drewes, AM; Malver, LP; Mansikka, H; Oksche, A, 2012)
"This study compared the efficacy and safety of a 3-day-type transdermal fentanyl patch conversion by the rapid titration method to short-acting oral oxycodone for cancer pain."5.16[Three-day-type transdermal fentanyl patch conversion by rapid titration method with short-acting oral oxycodone for cancer pain]. ( Fujio, N; Ishikawa, N; Kameyama, M; Watanabe, H; Yamazaki, K, 2012)
"A number of transmucosal fentanyl formulations have been developed for the management of breakthrough cancer pain (BTCP)."5.16Efficacy and safety of fentanyl sublingual spray for the treatment of breakthrough cancer pain: a randomized, double-blind, placebo-controlled study. ( Bull, J; Dillaha, L; Geach, J; Parikh, N; Rauck, R; Reynolds, L; Scherlis, M; Stearns, L, 2012)
"We prospectively investigated the reduced effects of adverse events caused by sustained-release oral morphine and controlled-release oxycodone after rotating to the fentanyl patch in patients with metastatic breast cancer."5.16[A pilot study of the reduced effects of adverse events caused by oral morphine and oxycodone after rotating to fentanyl patch in patients with metastatic breast cancer]. ( Fujii, S; Ikeda, M; Koike, Y; Kubo, S; Kurebayashi, J; Mizutou, A; Nakashima, K; Nomura, T; Oota, Y; Saitou, W; Seki, M; Shiiki, S; Shimo, T; Sonoo, H; Tanaka, K; Yamamoto, Y; Yamashita, T, 2012)
" Fentanyl patient-controlled analgesia was commenced to allow patients to self-regulate their pain relief."5.16Randomised trial of magnesium in the treatment of Irukandji syndrome. ( Bonin, R; Cullen, P; Gray, S; Little, M; McCullagh, N; Mulcahy, R; Pereira, P; Seymour, J, 2012)
"Data on the treatment of breakthrough cancer pain (BTcP) in patients receiving methadone therapy are lacking."5.15The use of fentanyl buccal tablets as breakthrough medication in patients receiving chronic methadone therapy: an open label preliminary study. ( Arcuri, E; Ferrera, P; Mercadante, S, 2011)
"3°C cold water), nerve growth factor-induced muscle soreness and intradermal capsaicin-induced hyperalgesia and allodynia."5.15Pharmacokinetic/pharmacodynamic relationships of transdermal buprenorphine and fentanyl in experimental human pain models. ( Andresen, T; Arendt-Nielsen, L; Christrup, LL; Drewes, AM; Foster, DJ; Upton, RN, 2011)
"Twenty-two healthy volunteers were randomized to treatment with transdermal buprenorphine (20 µg·h(-1), 144 h), fentanyl (25 µg·h(-1), 72 h) or placebo patches in a double-blind, cross-over experimental pain study."5.15Effect of transdermal opioids in experimentally induced superficial, deep and hyperalgesic pain. ( Andresen, T; Arendt-Nielsen, L; Drewes, AM; Mansikka, H; Oksche, A; Staahl, C, 2011)
"The combination of fentanyl and lidocaine before pin fixation is useful in preventing severe hemodynamic response to pain stimuli, such as pin fixation, and in increasing total antioxidant levels in the post-fixational period during craniotomy in adults."5.15Efficacy of fentanyl and/or lidocaine on total antioxidants and total oxidants during craniotomy. ( Alptekin, M; Erkutlu, I; Geyik, M; Gok, A; Mizrak, A; Oner, U; Sen, E, 2011)
"We recently reported that fentanyl pectin nasal spray (FPNS) provides superior pain relief from breakthrough cancer pain (BTCP) compared with immediate-release morphine sulfate (IRMS), with significant effects by five minutes and clinically meaningful pain relief from 10 minutes postdose."5.15Consistency of efficacy, patient acceptability, and nasal tolerability of fentanyl pectin nasal spray compared with immediate-release morphine sulfate in breakthrough cancer pain. ( Brooks, D; Davies, A; Elsner, F; Espinosa, J; Fallon, M; Reale, C; Sitte, T, 2011)
"The addition of 3% sevoflurane at the time of preoxygenation for 1 min along with routine use of lidocaine-tourniquet completely prevented pain upon propofol injection, whereas sevoflurane by itself provided similar analgesia to premixed lidocaine with propofol."5.15Sevoflurane to alleviate pain on propofol injection. ( Ali, MS; DeSousa, K, 2011)
"To compare the effectiveness of nitrous oxide/oxygen (N(2)O/O(2)) and fentanyl in relieving pain among patients with an isolated long bone fracture or main joint dislocation of the limbs."5.15Nitrous oxide/oxygen compared with fentanyl in reducing pain among adults with isolated extremity trauma: a randomized trial. ( Amini, A; Derakhshanfar, H; Dolatabadi, AA; Hatamabadi, H; Kariman, H; Majidi, A; Shahrami, A; Sheibani, K; Yaseri, M, 2011)
"Entonox provides better pain relief and faster recovery than midazolam-fentanyl and so is more effective for colonoscopy."5.14Randomized clinical trial of Entonox versus midazolam-fentanyl sedation for colonoscopy. ( Culbert, B; Duthie, GS; Gardiner, A; Hughes, M; Maslekar, S, 2009)
"This study assessed the long-term safety and tolerability of fentanyl buccal tablet (FBT) in opioid-tolerant patients with cancer and breakthrough pain (BTP) who were either naive to FBT or had completed 1 of 2 previous double-blind, placebo-controlled FBT studies (rollover patients)."5.14Fentanyl buccal tablet for the treatment of breakthrough pain in opioid-tolerant patients with chronic cancer pain: A long-term, open-label safety study. ( Messina, J; Weinstein, SM; Xie, F, 2009)
" However, remifentanil continuous infusion proved to offer significantly more stable pain control compared with the currently used combination fentanyl-midazolam."5.14Analgesia during abdominal aortic aneurysm endovascular repair: remifentanil vs. fentanyl-midazolam--a randomized controlled trial. ( Barbieri, A; Bonfreschi, V; Coppi, G; D'Amico, R; Giuliani, E; Malagnino, FC; Navi, A; Silingardi, R, 2009)
"This trial investigated the efficacy and long-term tolerability of intranasal fentanyl spray (INFS) 50 to 200 microg in the treatment of breakthrough pain in opioid-tolerant patients with cancer."5.14Efficacy and tolerability of intranasal fentanyl spray 50 to 200 microg for breakthrough pain in patients with cancer: a phase III, multinational, randomized, double-blind, placebo-controlled, crossover trial with a 10-month, open-label extension treatmen ( Colberg, T; Kaasa, S; Kaczmarek, Z; Kress, HG; Nolte, T; Orońska, A, 2009)
"The efficacy of intranasal fentanyl spray (INFS) was compared with that of oral transmucosal fentanyl citrate (OTFC) for the relief of cancer-related breakthrough pain (BTP) in an open-label, crossover trial."5.14A comparison of intranasal fentanyl spray with oral transmucosal fentanyl citrate for the treatment of breakthrough cancer pain: an open-label, randomised, crossover trial. ( Camba, MA; Colberg, T; Davies, A; Mercadante, S; Perkins, P; Poulain, P; Radbruch, L; Sitte, T, 2009)
"The primary objective of the present study was to determine the effectiveness of intranasal fentanyl analgesia in children aged 1-3 years with acute moderate to severe pain presenting to the ED."5.14Intranasal fentanyl in 1-3-year-olds: a prospective study of the effectiveness of intranasal fentanyl as acute analgesia. ( Cole, J; Shepherd, M; Young, P, 2009)
"The aim of this study was to compare the efficacy of intravenous pretreatment with fentanyl 50 microg, fentanyl 100 microg, and lidocaine 40 mg, preceded by venous occlusion, for reducing pain on injection of propofol in adult Japanese surgical patients."5.14A comparison of pretreatment with fentanyl and lidocaine preceded by venous occlusion for reducing pain on injection of propofol: a prospective, randomized, double-blind, placebo-controlled study in adult Japanese surgical patients. ( Fujii, Y; Itakura, M, 2009)
"Fentanyl buccal soluble film (FBSF) has been developed as a treatment of breakthrough pain in opioid-tolerant patients with cancer."5.14Fentanyl buccal soluble film (FBSF) for breakthrough pain in patients with cancer: a randomized, double-blind, placebo-controlled study. ( Finn, AL; Gever, LN; North, J; Rauck, R; Tagarro, I, 2010)
"In this study we evaluated the efficacy and tolerability of sublingual fentanyl (SLF) for breakthrough pain (BTP) in adult opioid-tolerant cancer patients."5.14Sublingual administration of fentanyl to cancer patients is an effective treatment for breakthrough pain: results from a randomized phase II study. ( Derrick, R; Frank-Lissbrant, I; Howell, J; Kälkner, KM; Lennernäs, B; Lennernäs, H, 2010)
"comparison of the fentanyl transdermal patch with injection of local anesthesia for intraoperative/postoperative pain from in-office Thermachoice III ablations."5.14In-office thermachoice III ablation: a comparison of two anesthetic techniques. ( Antonetti, AG; Chapa, HO; Sandate, J; Suvunrungsi, L; VanDuyne, CP; Venegas, G, 2010)
"This study evaluated the efficacy and safety of transdermal fentanyl in the outpatient treatment of head and neck cancer patients with pain caused by radiotherapy."5.14Transdermal fentanyl for pain caused by radiotherapy in head and neck cancer patients treated in an outpatient setting: a multicenter trial in Taiwan. ( Chang, JT; Chen, YJ; Lee, MS; Lin, CY; Lin, JC; Wang, HM, 2010)
"To determine if intranasal (IN) fentanyl is effective at decreasing pain that children feel during catheterization of VCUG when compared with sterile water."5.14Intranasal fentanyl versus placebo for pain in children during catheterization for voiding cystourethrography. ( Chung, S; Goldman, RD; Lim, R, 2010)
"kg(-1) added to bupivacaine significantly improves the quality of intraoperative analgesia and prolongs postoperative analgesia in children undergoing inguinal hernia repair with spinal anesthesia."5.14Effects of intrathecal fentanyl on quality of spinal anesthesia in children undergoing inguinal hernia repair. ( Apiliogullari, S; Duman, A; Duman, I, 2010)
"Data were obtained from the open titration phase of a multiple crossover, randomized, double-blind clinical trial comparing oral transmucosal fentanyl citrate with immediate-release oral morphine sulfate for the treatment of cancer-related breakthrough pain."5.14A comparison of change in the 0-10 numeric rating scale to a pain relief scale and global medication performance scale in a short-term clinical trial of breakthrough pain intensity. ( Berlin, JA; Farrar, JT; Polomano, RC; Strom, BL, 2010)
"The intent of our study was to compare the effects of dexmedetomidine versus midazolam on perioperative hemodynamics, sedation, pain, satisfaction and recovery scores during colonoscopy."5.14A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation. ( Budak, ET; Dagli, G; Dere, K; Filiz, AI; Ozkan, S; Sucullu, I; Yeyen, S, 2010)
"In these women who had undergone breast reduction or augmentation surgery, a single preprocedural dose of intranasal fentanyl was significantly more effective than placebo in reducing pain intensity over the hour after removal of surgical drains."5.14Pharmacokinetics, analgesic effect, and tolerability of a single preprocedural dose of intranasal fentanyl in patients undergoing drain removal after breast reduction or augmentation surgery: A prospective, randomized, double-blind, placebo-controlled stu ( Fiddelers, AA; Kessels, AG; Marcus, MA; Neef, C; Theunissen, HM; van der Hulst, RR; van der Kuy, PH; Veldhorst-Janssen, NM, 2010)
"This randomized, double-blind, crossover study assessed the efficacy and tolerability of a new rapid onset nasal fentanyl formulation (Fentanyl Pectin Nasal Spray; FPNS) for breakthrough cancer pain (BTCP)."5.14A multicenter, placebo-controlled, double-blind, multiple-crossover study of Fentanyl Pectin Nasal Spray (FPNS) in the treatment of breakthrough cancer pain. ( Burton, AW; Gabrail, N; Portenoy, RK; Taylor, D, 2010)
"To evaluate the time of onset, overall efficacy, and safety of fentanyl buccal tablet (FBT) for noncancer-related breakthrough pain (BTP) in opioid-tolerant adults over 12 weeks."5.14A novel 12-week study, with three randomized, double-blind placebo-controlled periods to evaluate fentanyl buccal tablets for the relief of breakthrough pain in opioid-tolerant patients with noncancer-related chronic pain. ( Farrar, JT; Messina, J; Portenoy, RK; Xie, F, 2010)
"We examined the efficacy and safety of a new transdermal fentanyl citrate patch (HFT-290), which was applied once daily in patients with cancer pain who were receiving a stable dose of once-every-three-day application transdermal fentanyl patch [TDF (72 hr)]."5.14[A phase II clinical study of once-a-day fentanyl citrate patch in patients with cancer pain--switching from once-every-three-days fentanyl patch to once-a-day fentanyl citrate patch]. ( Hashizume, T; Iseki, M; Iwao, Y; Kitajima, T; Masuda, Y; Matoba, M; Miyazaki, T; Namiki, A; Ogawa, S; Uchida, E, 2010)
"The aim of this study was to evaluate the effect and tolerability of low doses of transdermal (TD) fentanyl patches in opioid-naive patients with cancer pain."5.14Low doses of transdermal fentanyl in opioid-naive patients with cancer pain. ( Adile, C; Aielli, F; Ferrera, P; Ficorella, C; Mercadante, S; Porzio, G, 2010)
"The objective was to evaluate the use of a single 2 μg/kg dose of intranasal fentanyl as analgesia for painful orthopedic injuries in children presenting to a pediatric emergency department (ED)."5.14Use of intranasal fentanyl for the relief of pediatric orthopedic trauma pain. ( Adelgais, K; Nelson, D; Saunders, M, 2010)
" Simultaneous administration of dexamethasone and fentanyl have been known to decrease the duration of perineal pain but its role in alleviating perineal pain has not been studied."5.14Fentanyl pretreatment for alleviation of perineal symptoms following preoperative administration of intravenous dexamethasone sodium phosphate--a prospective, randomized, double blind, placebo controlled study. ( Garg, R; Rewari, V; Trikha, A, 2010)
"Omission of fentanyl did not reduce the overall incidence of postoperative nausea and vomiting, but did reduce the incidence of vomiting and/or moderate to severe nausea prior to discharge from 20% and 17% with fentanyl and fentanyl-dexamethasone, respectively, to 5% (P = 0."5.13Omitting fentanyl reduces nausea and vomiting, without increasing pain, after sevoflurane for day surgery. ( Bridgman, S; Smith, I; Walley, G, 2008)
"During the first 12 hr following the procedures, patients experienced significantly less vomiting/retching and less disruption of activity while receiving ondansetron, and recorded significantly lower pain scores while receiving fentanyl."5.13Pediatric oncology sedation trial (POST): A double-blind randomized study. ( Barr, RD; Buckley, N; Korz, L; Lappan, J; Nagel, K; Willan, AR, 2008)
"Fentanyl, a short-acting synthetic opioid, has a pharmacokinetic profile suited to fast relief of brief episodic pain."5.13Pharmacokinetics and pharmacodynamics of intranasal versus intravenous fentanyl in patients with pain after oral surgery. ( Christrup, L; Foster, D; Popper, L; Upton, R, 2008)
"We investigated the efficacy and safety of transdermal fentanyl for severe mucositis pain caused by chemotherapy."5.13Efficacy and safety of transdermal fentanyl for treatment of oral mucositis pain caused by chemotherapy. ( Cai, Q; Guo, Y; Huang, H; Li, Y; Lin, X; Sun, X; Xia, Z, 2008)
"We studied the effect of fentanyl pretreatment on alleviating pain during the injection of Propofol-Lipuro."5.13Fentanyl pre-treatment alleviates pain during injection of propofol-lipuro premixed with lignocaine. ( Ahmad, N; Balan, S; Zanariah, Y, 2008)
"Activation of DA and opioid neurotransmission by a pain stressor with and without placebo (changes in the binding potential of carbon 11 [11C]-labeled raclopride and [11C] carfentanil with positron emission tomography) and ratings of pain, affective state, and anticipation and perception of analgesia."5.13Placebo and nocebo effects are defined by opposite opioid and dopaminergic responses. ( Egnatuk, CM; Koeppe, RA; Scott, DJ; Stohler, CS; Wang, H; Zubieta, JK, 2008)
"Fifty-eight patients who were undergoing SWL for renal calculi were randomized to receive intravenously either fentanyl citrate (group A, n = 30) or parecoxib sodium (group B, n = 28) when they felt that their pain during the session became intolerable."5.13Analgesia during extracorporeal shockwave lithotripsy: fentanyl citrate versus parecoxib sodium. ( Anagnostou, T; Gravas, S; Karatzas, A; Melekos, MD; Mitsogiannis, IC; Poulakis, V; Tzortzis, V, 2008)
"To compare the efficacy of fentanyl and remifentanil as prodrugs in the prevention of rocuronium injection pain by using a control group."5.13Comparison of the effectiveness of pretreatment by fentanyl and remifentanil on rocuronium induced injection pain. ( Bayindir, S; Ellidokuz, H; Gunerli, A; Iyilikci, L; Sari, M, 2008)
"Fentanyl is a synthetic opioid used to treat intense chronic pain."5.13Determination of fentanyl in sweat and hair of a patient using transdermal patches. ( Ait-M-Bark, Z; Appenzeller, B; Lemmer, P; Schneider, S; Schummer, C; Wennig, R; Yegles, M, 2008)
" administration of fentanyl in acute, episodic pain in patients undergoing third-molar extraction."5.13Pharmacokinetics, efficacy, and tolerability of fentanyl following intranasal versus intravenous administration in adults undergoing third-molar extraction: a randomized, double-blind, double-dummy, two-way, crossover study. ( Christrup, LL; Foster, D; Popper, LD; Troen, T; Upton, R, 2008)
"A novel transdermal matrix patch delivery system for fentanyl has been developed to deliver improved management of cancer pain compared with that obtained using current fentanyl reservoir patches."5.13Efficacy, safety and pharmacokinetic study of a novel fentanyl-containing matrix transdermal patch system in Japanese patients with cancer pain. ( Hanaoka, K; Hosokawa, T; Ishida, T; Kitajima, T; Mashimo, S; Miyazaki, T; Namiki, A; Nogami, S; Ogawa, S, 2008)
"The comparison of ketamine with fentanyl for pain control of pediatric orthopedic emergencies remains controversial."5.12Influence of ketamine versus fentanyl on pain relief for pediatric orthopedic emergencies: A meta-analysis of randomized controlled studies. ( Qiu, J; Xie, M, 2021)
" The patient is a 50-year-old female with widely metastatic breast cancer who developed opioid toxicity when maintenance transdermal fentanyl patch therapy (100 μg patch applied every 72 h) was rotated to subcutaneous hydromorphone infusion to improve pain control."5.12Opioid rotation from transdermal fentanyl to continuous subcutaneous hydromorphone in a cachectic patient: A case report and review of the literature. ( Chua, D; Jackson, LD; Selby, D; Wortzman, R, 2021)
"In this study, the analgesic efficiency and adverse events of oxycodone and other opioids, including alfentanil, sufentanil, fentanyl, and morphine, in treating post-laparoscopic surgery visceral pain were evaluated."5.12Oxycodone versus other opioid analgesics after laparoscopic surgery: a meta-analysis. ( Dou, Z; Li, Y; Ma, J; Ni, J; Wang, Q; Yang, L, 2021)
"These finding suggest that use of PCEA with bupivacaine and fentanyl is more effective in managing pain related to HDR brachytherapy for prostate cancer, and results in a positive patient outcome thereby improving patient satisfaction."5.12Prostate HDR radiation therapy: a comparative study evaluating the effectiveness of pain management with peripheral PCA vs. PCEA. ( Block, M; Colella, J; Galli, B; Gejerman, G; Knorr-Mulder, C; Lanteri, V; Levey, S; Sawczuk, I; Scheuch, J; Scrofine, S; Siegel, A; Watson, R, 2006)
"This trial demonstrated that the lower 12 microg/h dose of fentanyl TTS provided a therapeutic benefit in non-malignant chronic pain, with a similar AE rate but a lower drop-out rate than that seen in trials at higher doses."5.12A Phase III study to assess the clinical utility of low-dose fentanyl transdermal system in patients with chronic nonmalignant pain. ( Otis, J; Rothman, M, 2006)
"The routine use of fentanyl and midazolam prior to sheath removal leads to a reduction in pain perception and vasovagal incidence, whilst the routine use of local infiltration during sheath removal should be discouraged as it leads to more pain and a trend to more vasovagal reactions."5.12Effect of local anesthesia and intravenous sedation on pain perception and vasovagal reactions during femoral arterial sheath removal after percutaneous coronary intervention. ( French, JK; Juergens, CP; Kiat Ang, C; Leung, DY; Lo, S, 2007)
"We compare the efficacy of intranasal fentanyl versus intravenous morphine in a pediatric population presenting to an emergency department (ED) with acute long-bone fractures."5.12A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department. ( Borland, M; Jacobs, I; King, B; O'Brien, D, 2007)
"2% ropivacaine hydrochloride without bolus administration reduces the incidence of hypotension by 67% and is safer than traditional bolus dosing for routine labor."5.12Hemodynamic stability during labor and delivery with continuous epidural infusion. ( Gerhardt, MA; Gunka, VB; Miller, RJ, 2006)
"Acceptable operative conditions with a low incidence of hypotension are provided with an 11 mg dose of hyperbaric bupivacaine."5.12[Hyperbaric bupivacaine: a randomized double-blind trial of different doses with or without fentanyl for cesarean section under spinal anesthesia]. ( Abengochea Cotaina, A; Bernat García, J; Gallego García, J, 2007)
"Fifty-six adults with chronic noncancer pain using oral transmucosal fentanyl citrate (OTFC, ACTIQ)."5.12Impact of breakthrough pain on quality of life in patients with chronic, noncancer pain: patient perceptions and effect of treatment with oral transmucosal fentanyl citrate (OTFC, ACTIQ). ( Chun, SY; Fortner, B; Reinking, J; Shoemaker, S; Stegman, M; Taylor, DR; Webster, LR, 2007)
"Patients experiencing pain during daily dressing changes were given entonox plus either placebo or oral transmucosal fentanyl citrate (OTFC) for two consecutive dressing changes in a randomised double-blind placebo-controlled crossover trial."5.12Oral transmucosal fentanyl citrate versus placebo for painful dressing changes: a crossover trial. ( Barker, L; Larsen, D; MacIntyre, PA; Margetts, L, 2007)
" Here we examined the time-course of changes in BP during a nonpharmacological challenge, moderate levels of sustained pain, shown to induce robust reductions in micro-opioid and DA D2 BP, as measured with [(11)C]carfentanil and [(11)C]raclopride."5.12Time-course of change in [11C]carfentanil and [11C]raclopride binding potential after a nonpharmacological challenge. ( Koeppe, RA; Scott, DJ; Stohler, CS; Zubieta, JK, 2007)
" This is the first study to investigate the absorption profile of fentanyl buccal tablet (FBT) - an effervescent formulation of fentanyl indicated for the management of breakthrough pain in opioid-tolerant cancer patients - in patients with or without oral mucositis."5.12Absorption of fentanyl from fentanyl buccal tablet in cancer patients with or without oral mucositis: a pilot study. ( Darwish, M; Jiang, JG; Kirby, M; Robertson, P; Tracewell, W, 2007)
"The use of OTFC can provide improved pain control when compared with IV morphine."5.12A randomized clinical trial of oral transmucosal fentanyl citrate versus intravenous morphine sulfate for initial control of pain in children with extremity injuries. ( Christopher, NC; Kennedy, CS; Mahar, PJ; Rana, JA, 2007)
"To compare the pain relief achieved with nebulized fentanyl citrate with intravenous (i."5.12Randomized clinical trial of nebulized fentanyl citrate versus i.v. fentanyl citrate in children presenting to the emergency department with acute pain. ( Biros, MH; Herold, M; Hubbard, D; Kletti, C; Miner, JR, 2007)
" In this randomized open-label study the influence of tramadol on dose adjustment of transdermal fentanyl in advanced cancer pain control was prospectively evaluated."5.12Improved cancer pain treatment using combined fentanyl-TTS and tramadol. ( Aloisio, L; Bajocco, C; Ciccozzi, A; Coaccioli, S; Colangeli, A; Marinangeli, F; Paladini, A; Varrassi, G, 2007)
"Various strategies have been studied to reduce the discomfort of rocuronium pain."5.12Effect of narcotic pretreatment on pain after rocuronium injection: a randomized, double-blind controlled comparison with lidocaine. ( Bithal, PK; Chauhan, H; Dash, HH; Prabhakar, H; Rath, GP; Singh, M, 2007)
"To compare the effects of providing analgesia with either transdermal fentanyl (TTS-fentanyl) or paracetamol and codeine (P/C) in addition to radiotherapy in patients with metastatic bone pain."5.11Radiotherapy plus either transdermal fentanyl or paracetamol and codeine for painful bone metastases: a randomised study of pain relief and quality of life. ( Eleftheriadis, N; Georgakopoulos, G; Gompakis, N; Kouloulias, VE; Kouvaris, J; Mystakidou, K; Pistevou-Gompaki, K; Varveris, C, 2004)
"To determine the safety and efficacy of transdermal fentanyl for pain relief in cancer patients and to compare the effects on patients according to whether they had previously received strong opioids, weak opioids or non-opioid analgesia."5.11Use of transdermal fentanyl without prior opioid stabilization in patients with cancer pain. ( Bryuzgin, V; Kourteva, G; Tawfik, MO, 2004)
"The aim of this observational study was to examine pain management outcomes and quality of life (QoL) measures in cancer patients with intolerable or chronic severe pain transferring from World Health Organization's step I, II, and III analgesics to the transdermal therapeutic fentanyl system (TTS-F)."5.11Pain management of cancer patients with transdermal fentanyl: a study of 1828 step I, II, & III transfers. ( Georgaki, S; Katsouda, E; Kouloulias, V; Kouvaris, J; Mystakidou, K; Parpa, E; Tsilika, E; Vlahos, L, 2004)
"This study sought to compare the analgesic efficacy and safety of patient controlled intra-nasal (PCIN) fentanyl with oral morphine for procedural wound care in burns patients."5.11A randomised crossover trial of patient controlled intranasal fentanyl and oral morphine for procedural wound care in adult patients with burns. ( Finn, J; Fong, J; Gelavis, A; Leslie, G; Mackenzie, E; Wood, F; Wright, J, 2004)
"In this randomized, double-blinded study in 60 ASA I or II adults with >20% body-surface area thermal burns, we investigated the feasibility of patient-controlled analgesia (PCA) with fentanyl for pain management during dressing changes and determined the optimal PCA-fentanyl demand dose."5.11Patient-controlled analgesia with fentanyl for burn dressing changes. ( Fatima, T; Pawar, M; Prakash, S, 2004)
"Sufentanil, a potent mu-opioid agonist, historically has not been been given systemically to treat chronic pain."5.11Relative analgesic potency of fentanyl and sufentanil during intermediate-term infusions in patients after long-term opioid treatment for chronic pain. ( Charapata, S; DuPen, S; Fisher, DM; Heinze, E; Katz, N; Portenoy, R; Rauck, R; Reynolds, L; Wallace, M; Webster, L, 2004)
"Oral transmucosal fentanyl citrate can provide an alternative means of delivering effective, rapid-onset, and noninvasive pain management in an out-of-hospital, combat, or austere environment."5.11A novel pain management strategy for combat casualty care. ( Holcomb, JB; Johnson, TR; Kotwal, RS; Meyer, DE; Mosely, DS; O'Connor, KC, 2004)
"Fentanyl is commonly used for spinal analgesia during labour but it is associated with a high incidence of pruritus."5.11Intrathecal fentanyl-induced pruritus during labour: the effect of prophylactic ondansetron. ( Evans, SF; Paech, MJ; Wells, J, 2004)
"We treated 50 patients with chronic nonmalignant pain using transdermal fentanyl (TDF) 25 microg/hr and concurrently measured pain using a visual analog scale (VAS) and serum cortisol concentration."5.11The effect of transdermal fentanyl treatment on serum cortisol concentrations in patients with non-cancer pain. ( Altan, A; Ozyuvaci, E; Yanmaz Alnigenis, N, 2004)
"We investigated the early recovery characteristics and pain relief of adult patients during combined anesthesia with (epidural and general), either with propofol or sevoflurane for maintenance in major abdominal surgery."5.11Propofol and sevoflurane during epidural/general anesthesia: comparison of early recovery characteristics and pain relief. ( Duru, S; Elar, Z; Hepağuşlar, H; Ozkardeşler, S; Ozzeybek, D; Taşdöğen, A, 2004)
"This study evaluated transdermal fentanyl (TDF) for the treatment of pain from rheumatoid arthritis (RA) which was not adequately controlled by nonopioid analgesics and/or weak opioids."5.11Transdermal fentanyl for the treatment of pain caused by rheumatoid arthritis. ( Bjorneboe, O; Herrero-Beaumont, G; Richarz, U, 2004)
"A study of the urinary concentration of fentanyl (F) and its major metabolite norfentanyl (NF) in chronic pain patients treated with the Duragesic continuous release transdermal patches is presented."5.11Urine concentrations of fentanyl and norfentanyl during application of Duragesic transdermal patches. ( Backer, R; Poklis, A, 2004)
" This study observed whether a single dose of 50 mcg intravenous fentanyl reduces pain, improving compliance, acceptability, and completion rates."5.11Value of fentanyl in flexible sigmoidoscopy. ( Basu, S; Krishnamurthy, B; Walsh, TH, 2004)
" Fentanyl also may reduce the pain of diazepam injection by blocking the opiate receptors in vessels walls."5.11The effect of ketamine and fentanyl in reducing the pain of diazepam injection. ( Azemati, M; Azemati, S; Khosravi, A; Khosravi, MB, 2004)
"To evaluate the effectiveness and safety of transdermal fentanyl (TDF) for the treatment of pain associated with rheumatoid arthritis (RA) or osteoarthritis of the knee or hip (OA), which was not adequately controlled by non-opioid analgesics and/or weak opioids."5.11Benefits of transdermal fentanyl in patients with rheumatoid arthritis or with osteoarthritis of the knee or hip: an open-label study to assess pain control. ( Bjorneboe, O; Herrero-Beaumont, G; Le Loet, X; Pavelka, K; Richarz, U, 2004)
"This study was designed to evaluate the utility of transdermal fentanyl (TDF, Durogesic) for the treatment of pain due to osteoarthritis (OA) of the knee or hip, which was not adequately controlled by non-opioid analgesics or weak opioids."5.11Transdermal fentanyl for the treatment of pain caused by osteoarthritis of the knee or hip: an open, multicentre study. ( Le Loët, X; Pavelka, K; Richarz, U, 2005)
"We evaluated the effects of gabapentin and carbamazepine for pain relief in 36 Guillain-Barré syndrome patients."5.11The comparative evaluation of gabapentin and carbamazepine for pain management in Guillain-Barré syndrome patients in the intensive care unit. ( Kumar, A; Navkar, DV; Pandey, CK; Raza, M; Singh, UK; Tripathi, M, 2005)
"Although recent studies suggest that opioid rotation could be an effective treatment strategy for morphine-induced delirium, there have been no prospective studies to investigate the treatment effects of opioid rotation using fentanyl."5.11Opioid rotation from morphine to fentanyl in delirious cancer patients: an open-label trial. ( Akechi, T; Ikenaga, M; Matsubara, T; Miyoshi, I; Morita, T; Onishi, H; Tajima, T; Takigawa, C; Tani, K; Uchitomi, Y, 2005)
"Pre-operative administration of oral etoricoxib 120 mg decreased the use of fentanyl and pain scores after minor gynaecological surgery without significant side effects."5.11Analgesic efficacy of pre-operative etoricoxib for termination of pregnancy in an ambulatory centre. ( Chiu, JW; Lim, Y; Liu, W; Loo, CC; Ren, HZ; Tan, HM, 2005)
"Chronic pain can be effectively treated with fentanyl-TTS, which has a very favorable side effect profile."5.11[Individual aspects of the quality of life of patients with chronic pain. Observational study of treatment with fentanyl-TTS]. ( Waap, I; Zimmermann, M, 2005)
"The study objective was to determine whether switching patients from morphine to transdermal fentanyl resulted in a reduction of morphine-associated side effects, and an improvement in cognitive function and patients' well being while maintaining adequate pain and symptom control."5.10Opioid switching from morphine to transdermal fentanyl for toxicity reduction in palliative care. ( McNamara, P, 2002)
"The pain and distress ratings of patients undergoing BMAs (n = 73) and LPs (n = 105) were examined in a comparison of 3 different interventions: (1) a topical eutectic mixture of lidocaine and prilocaine (EMLA cream), (2) oral midazolam and EMLA cream, or (3) propofol/fentanyl general anesthesia."5.10Pain and distress from bone marrow aspirations and lumbar punctures. ( Doran, NH; Frost, JD; Holdsworth, MT; Mathew, P; Moro, MA; Pankey, JM; Phillips, J; Raisch, DW; Winter, SS, 2003)
"When compared with rocuronium alone, only the addition of saline failed to significantly reduce the pain reported by patients."5.10Comparison of four strategies to reduce the pain associated with intravenous administration of rocuronium. ( Chiarella, AB; Clanachan, AS; Huston, CM; Jolly, DT, 2003)
" Although the visual analog scale, Observer's Assessment of Alertness/Sedation Scale, and State and Trait Anxiety Inventory-State Anxiety test did not show statistically significant differences, the State and Trait Anxiety Inventory-Trait Anxiety score was found to be lower in the music group (group 2) than in the midazolam group (group 1)."5.10Music decreases anxiety and provides sedation in extracorporeal shock wave lithotripsy. ( Basar, H; Basar, M; Batislam, E; Ferhat, M; Ozcan, S; Yilmaz, E, 2003)
"The findings suggest that a single lumbar epidural dose of fentanyl should be injected at the spinal interspace corresponding to the dermatomal site of pain."5.10Lumbar epidural fentanyl: segmental spread and effect on temporal summation and muscle pain. ( Arendt-Nielsen, L; Curatolo, M; Eichenberger, U; Giani, C; Graven-Nielsen, T; Petersen-Felix, S, 2003)
" The addition of a small 125- micro g dose of morphine improves pain control during subsequent epidural analgesia and reduces the requirements for postpartum pain medications."5.10Small dose bupivacaine-fentanyl spinal analgesia combined with morphine for labor. ( Hess, PE; Pratt, SD; Snowman, C; Vasudevan, A, 2003)
"To determine the effects of systemic fentanyl analgesia in preventing the pain related to the administration of retrobulbar anesthesia and cataract surgery."5.10Effects of fentanyl on pain and hemodynamic response after retrobulbar block in patients having phacoemulsification. ( Ermis, SS; Inan, UU; Oztürk, F; Sivaci, RG, 2003)
"To measure the plasma fentanyl concentrations achieved over time with transdermal fentanyl patches in awake cats and cats undergoing anesthesia and ovariohysterectomy."5.10Plasma fentanyl concentrations in awake cats and cats undergoing anesthesia and ovariohysterectomy using transdermal administration. ( Allen, SW; Egger, CM; Glerum, LE; Haag, M, 2003)
"In an experimental pain study in volunteers, epidural fentanyl caused segmental analgesia when administered as a bolus and nonsegmental systemic analgesia when administered as a continuous infusion."5.10The site of action of epidural fentanyl in humans: the difference between infusion and bolus administration. ( Angst, MS; Ginosar, Y; Riley, ET, 2003)
"This randomised, multicentre, direct open comparative trial evaluated the efficacy, treatment convenience, tolerability and safety aspects of transdermal therapeutic system (TTS)-fentanyl and sustained-release oral morphine (SRM) in both opioid-naïve patients with moderate-to-severe cancer-related pain and in patients who had already been using opioids for mild-to-moderate pain."5.10Comparison of TTS-fentanyl with sustained-release oral morphine in the treatment of patients not using opioids for mild-to-moderate pain. ( Schipper, RM; Smit, JM; van Seventer, R; Wicks, MA; Zuurmond, WW, 2003)
"Transdermal therapeutic system-fentanyl (TTS-F) has been extensively studied in cancer pain management."5.10Long-term management of noncancer pain with transdermal therapeutic system-fentanyl. ( Georgaki, S; Mavromati, A; Mystakidou, K; Parpa, E; Smyrniotis, V; Tsilika, E; Vlahos, L, 2003)
"We conclude that the use of fentanyl (7 microg kg(-1)) was not effective in suppressing the catecholamine release, following painful surgical stimulation in brain-dead organ donors."5.10Intraoperative catecholamine release in brain-dead organ donors is not suppressed by administration of fentanyl. ( Fitzgerald, RD; Hieber, C; Lackner, FX; Luo, A; Oczenski, W; Schweitzer, E, 2003)
"Analgesic treatment with TTS fentanyl used as a single opioid is effective and safe for cancer pain relief, given that is cautiously applied, in patients requiring strong opioid analgesics even if they were naive to strong or mild opioids."5.10Use of TTS fentanyl as a single opioid for cancer pain relief: a safety and efficacy clinical trial in patients naive to mild or strong opioids. ( Befon, S; Dardoufas, K; Georgaki, S; Mystakidou, K; Tsilika, E; Vlahos, L, 2002)
"The successful use of methadone in cancer pain has been supported by numerous case reports and clinical studies."5.10Pitfalls of opioid rotation: substituting another opioid for methadone in patients with cancer pain. ( Derby, S; Fischberg, D; Kornick, C; Manfredi, PL; Moryl, N; Payne, R; Santiago-Palma, J, 2002)
" In the postanesthesia care unit (PACU), fentanyl 25 microg was administered for a verbal analog scale (VAS) pain score >or=3."5.10Preoperative administration of controlled-release oxycodone for the management of pain after ambulatory laparoscopic tubal ligation surgery. ( Joshi, W; Maciolek, H; Reuben, SS; Steinberg, RB, 2002)
"We compared the efficacy of ondansetron, lidocaine, tramadol, and fentanyl in minimizing pain caused by the injection of rocuronium in 250 patients."5.10The prevention of pain from injection of rocuronium by ondansetron, lidocaine, tramadol, and fentanyl. ( Karamanlioğlu, B; Memiş, D; Pamukçu, Z; Süt, N; Turan, A, 2002)
"We examined the effects of injection rate of propofol on injection pain and postinduction hypotension and bradycardia when fentanyl was administrated before propofol."5.09[Effects of speed of injection on anesthesia induction with propofol and fentanyl]. ( Ichimiya, T; Kamada, Y; Kobayashi, Y; Namiki, A; Seki, S; Tsuchida, A, 1999)
") morphine and fentanyl with respect to pain control and side effects using a 6-day randomized, double-blind, cross-over design."5.09A comparison of subcutaneous morphine and fentanyl in hospice cancer patients. ( Brooksbank, M; Fazekas, B; Hunt, R; Thorne, D, 1999)
"The short duration of effective analgesia produced by intrathecal fentanyl (ITF) at doses ranging from 5 to 25 micrograms limits the drug's use for the management of labor pain."5.09Effect of intrathecal fentanyl dose on the duration of labor analgesia. ( Celeski, DC; Haas, J; Heindel, L; Vacchiano, CA, 1999)
"5 mg bupivacaine given intrathecally via combined spinal epidural (CSE) for labour pain relief in the first stage."5.09Combined spinal epidural for labour analgesia--duration, efficacy and side effects of adding sufentanil or fentanyl to bupivacaine intrathecally vs plain bupivacaine. ( Chen, LH; Chong, JL; Lo, WK, 1999)
"Constipation and the use of laxatives were investigated in patients with chronic cancer pain treated with oral morphine and transdermal fentanyl in an open sequential trial."5.09Constipation and the use of laxatives: a comparison between transdermal fentanyl and oral morphine. ( Grond, S; Kasper, M; Kulbe, C; Lehmann, KA; Loick, G; Radbruch, L; Sabatowski, R, 2000)
"Transdermal Fentanyl (TF, Durogesic) is a strong opioid analgesic which is used in the treatment of cancer pain."5.09[Research from the Palliative Care Department in Poznań on treatment of neoplasm pain with Durogesic (transdermal fentanyl)]. ( Gorzelińska, L; Kozikowska, J; Leppert, W; Luczak, J, 2000)
"To compare patients' preference for transdermal fentanyl or sustained release oral morphine, their level of pain control, and their quality of life after treatment."5.09Randomised crossover trial of transdermal fentanyl and sustained release oral morphine for treating chronic non-cancer pain. ( Allan, L; Bolt, M; de Waroux, BL; Donald, R; Hays, H; Jensen, NH; Kalso, E, 2001)
"Our aim was to find out whether intravenous fentanyl was effective in reducing the pain of first-trimester abortion."5.09A randomized controlled trial of fentanyl for abortion pain. ( Rawling, MJ; Wiebe, ER, 2001)
"This open-label study evaluated the long-term safety and tolerability of oral transmucosal fentanyl citrate (OTFC) in ambulatory cancer patients with breakthrough pain undergoing cancer care at 32 university- or community-based practices."5.09Long-term safety of oral transmucosal fentanyl citrate for breakthrough cancer pain. ( Berris, R; Busch, MA; Coluzzi, P; Hart, L; Loseth, DB; Lyss, A; Nordbrook, E; Payne, R; Portenoy, RK; Rauck, R; Simmonds, M, 2001)
"Therapeutic fentanyl blood levels are reached approximately 12-16 hours after the initial application of transdermal fentanyl patches."5.09A safe and effective method for converting cancer patients from intravenous to transdermal fentanyl. ( Khojainova, N; Kornick, CA; Manfredi, PL; Payne, R; Primavera, LH; Santiago-Palma, J, 2001)
"Both etofenamate and fentanyl have clinically sufficient effects on pain, and can be used safely for outpatient ESWL procedures."5.09Comparative study of etofenamate and fentanyl for outpatient extracorporeal shockwave lithotripsy. ( Bozoklu, A; Cimentepe, E; Sağlam, R; Unsal, A, 2001)
"The effects of sublingual fentanyl citrate (SLFC) were assessed in 11 hospice inpatients with cancer-related breakthrough pain."5.09Sublingual fentanyl citrate for cancer-related breakthrough pain: a pilot study. ( Zeppetella, G, 2001)
"The first clinical experience in the United States of the transdermal therapeutic system (TTS) for delivery of fentanyl in cancer pain was a small study of five patients."5.08Transdermal fentanyl: clinical development in the United States. ( Simmonds, MA, 1995)
"To investigate the efficacy and safety of oral transmucosal fentanyl (OTFC) in providing analgesia and sedation for painful diagnostic procedures in children."5.08The use of oral transmucosal fentanyl citrate for painful procedures in children. ( Bernstein, B; Conard, PL; Rosenblum, M; Schechter, NL; Weisman, SJ, 1995)
"Direct conversion from oral morphine to transdermal fentanyl with a ratio of oral morphine/transdermal fentanyl (100:1 mg) daily was examined in patients with cancer pain."5.08Direct conversion from oral morphine to transdermal fentanyl: a multicenter study in patients with cancer pain. ( Donner, B; Strumpf, M; Tryba, M; Zenz, M, 1996)
"We performed an open-label pilot study to define analgesic efficacy, acceptability, and toxicity of transdermal fentanyl in an ambulatory population of patients with cancer pain."5.08Transdermal fentanyl in the management of cancer pain in ambulatory patients: an open-label pilot study. ( Fidler, P; Hammack, JE; Loprinzi, CL; Mailliard, JA; Michalak, JC; Miser, AW; O'Fallon, JR; Reuter, NF; Rospond, RM; Wilwerding, MB, 1996)
"To compare the local efficacy of lidocaine and fentanyl in reducing propofol injection pain (PIP), we conducted a prospective randomized double-blind study in 75 ASA I and II adult patients."5.08Reduction of propofol pain--fentanyl vs lidocaine. ( Alyafi, WA; Rangasami, J, 1996)
"We compared the analgesic effect of intravenous dose titration of fentanyl with diazepam (active placebo) or saline (inert placebo) in 53 patients with different types of neuropathic pain."5.08Randomised double-blind active-placebo-controlled crossover trial of intravenous fentanyl in neuropathic pain. ( Dellemijn, PL; Vanneste, JA, 1997)
" A high incidence of pain with drug injection was noted among patients receiving propofol (80%)."5.08Propofol patient-controlled sedation during hip or knee arthroplasty in elderly patients. ( Ganapathy, S; Gelb, AW; Herrick, IA; Kirkby, J, 1997)
"A prospective phase II study was conducted to define the analgesic efficacy, acceptability and toxicity of the transdermal therapeutic system (TTS) of fentanyl in Chinese patients with severe cancer-related pain."5.08Transdermal fentanyl for severe cancer-related pain. ( Chan, AT; Johnson, PJ; Lam, KK; Leung, TW; Nip, SY; Yeo, W, 1997)
" This study was designed to: 1) compare the safety and efficacy of intravenous fentanyl, intravenous fentanyl combined with midazolam, and intramuscular meperidine-promethazine-chlorpromazine (MPC) compound when used for painful emergency department (ED) procedures: and 2) to determine whether the addition of et-CO2 monitoring enabled earlier identification of respiratory depression in this population."5.08The value of end-tidal CO2 monitoring when comparing three methods of conscious sedation for children undergoing painful procedures in the emergency department. ( Berns, SD; Boenning, DA; Hart, LS; Houck, CS, 1997)
" pretreatment with fentanyl, morphine, meperidine, or lidocaine in reducing propofol injection pain."5.08The analgesic effect of fentanyl, morphine, meperidine, and lidocaine in the peripheral veins: a comparative study. ( Huang, S; Hwang, MH; Mok, MS; Pang, WW, 1998)
"A cohort of patients with cancer who had participated in a placebo-controlled, randomized study that documented the efficacy of oral transmucosal fentanyl citrate for painful procedures rated the pain associated with subsequent procedures performed with open-label oral transmucosal fentanyl."5.08Consequences of inadequate analgesia during painful procedures in children. ( Bernstein, B; Schechter, NL; Weisman, SJ, 1998)
"To compare pain-related treatment satisfaction, patient-perceived side effects, functioning, and well-being in patients with advanced cancer who were receiving either transdermal fentanyl (Duragesic, Janssen Pharmaceuticals, Titusville, NJ) or sustained-release oral forms of morphine (MS Contin, Perdue Frederick Co, Norwalk, CT, or Oramorph SR, Roxanne Laboratories, Columbus, OH)."5.08Quality of life and cancer pain: satisfaction and side effects with transdermal fentanyl versus oral morphine. ( Mahmoud, R; Mathias, SD; Pasta, DJ; Payne, R; Wanke, LA; Williams, R, 1998)
") retention of fentanyl and lidocaine in reducing the pain on i."5.08Comparison of intravenous retention of fentanyl and lidocaine on local analgesia in propofol injection pain. ( Chang, DP; Chung, YT; Hong, MH; Huang, S; Lin, SS; Pang, WW, 1997)
"Patients who were 18 years of age or older, receiving the equivalent of at least 60 mg oral morphine or at least 50 microg transdermal fentanyl per day for chronic cancer-related pain, and experiencing at least one episode of breakthrough pain per day were studied."5.08Oral transmucosal fentanyl citrate: randomized, double-blinded, placebo-controlled trial for treatment of breakthrough pain in cancer patients. ( Busch, M; Cleary, J; Farrar, JT; Nordbrock, E; Rauck, R, 1998)
"Single doses of fentanyl analgesia can reduce the physiologic/behavioral measures of pain and stress associated with mechanical ventilation in preterm infants."5.08Physiological, hormonal, and behavioral responses to a single fentanyl dose in intubated and ventilated preterm neonates. ( Anand, KJ; de Almeida, MF; Guinsburg, R; Kopelman, BI; Miyoshi, MH; Peres, Cde A, 1998)
"Pain on injection is one of the well-known side effects of propofol."5.08[Pain-free injection of propofol]. ( Ichimiya, T; Kamada, Y; Kobayashi, Y; Kumagai, A; Namiki, A; Seki, S; Tsuchida, H, 1998)
"We compared the effect of fentanyl and lidocaine on pain during injection of propofol."5.08[Reduction of pain on injection of propofol: a comparison of fentanyl with lidocaine]. ( Aketa, K; Ichimiya, T; Kobayashi, Y; Naganuma, R; Namiki, A; Seki, S, 1998)
"This was a multicenter, randomized, double-blind, dose-titration study in 62 adult cancer patients using transdermal fentanyl for persistent pain."5.08Dose-titration, multicenter study of oral transmucosal fentanyl citrate for the treatment of breakthrough pain in cancer patients using transdermal fentanyl for persistent pain. ( Busch, MA; Christie, JM; Coluzzi, P; Nordbrock, E; Patt, R; Portenoy, RK; Simmonds, M, 1998)
"To establish the analgesic effective doses as defined as a visual analog pain scale (VAS) of at least 10 for 95% of parturients (ED95) receiving either epidural fentanyl or sufentanil with bupivacaine 0."5.08Determination of the analgesic dose-response relationship for epidural fentanyl and sufentanil with bupivacaine 0.125% in laboring patients. ( Gadalla, F; Herman, NL; Koff, HD; Reynolds, JE; Rubin, JD; Sheu, KL; Van Decar, TK, 1998)
"All communications on the use of transdermal fentanyl as well as the recommendations of the manufacturer include the direction that patients should be titrated with a short-acting narcotic to control their cancer pain before they are converted to a fentanyl transdermal therapeutic system (TTS)."5.07Transdermal fentanyl in uncontrolled cancer pain: titration on a day-to-day basis as a procedure for safe and effective dose finding--a pilot study in 20 patients. ( Korte, W; Morant, R, 1994)
"At Helsinki University Central Hospital in Finland, clinical researchers divided 169 women into two groups (group 1: diagnostic laparoscopies; group 2: laparoscopic sterilizations) as part of a study to evaluate the effect of intravenous diclofenac on postoperative pain, nausea, and recovery after outpatient gynecological laparoscopy."5.07Effect of intravenous diclofenac on pain and recovery profile after day-case laparoscopy. ( Hovorka, J; Kallela, H; Korttila, K, 1993)
"The effect of fentanyl, administered immediately before propofol, when pain is experienced at the site of propofol injection was studied in 28 children undergoing elective surgery."5.07[Fentanyl prevents the pain at the site of propofol injection]. ( Chessa, D; Cossu, F; Serra, G, 1992)
"Transdermal fentanyl is a new fentanyl delivery system recently approved by the FDA for use in patients with chronic pain."5.07Transdermal fentanyl: clinical trial at the University of Colorado Health Sciences Center. ( Slover, R, 1992)
"In this study, 6 patients with pain from advanced cancer were enrolled in a multicenter, open-label seeding trial of transdermal fentanyl."5.07Transdermal fentanyl: seeding trial in patients with chronic cancer pain. ( Kedziera, P; Levy, MH; Rosen, SM, 1992)
"Patients were entered into an open label study to evaluate the efficacy of transdermal fentanyl as an analgesic for chronic cancer pain."5.07Transdermal fentanyl for chronic cancer pain: detailed case reports and the influence of confounding factors. ( Hogan, LA; Patt, RB, 1992)
"In this study, 11 cancer patients who experienced severe pain were treated with transdermal fentanyl."5.07Transdermal fentanyl use in hospice home-care patients with chronic cancer pain. ( Herbst, LH; Strause, LG, 1992)
"A multicenter study was conducted to determine the patient and physician acceptability of transdermal fentanyl in the management of cancer-related pain."5.07Management of cancer pain with transdermal fentanyl: phase IV trial, University of Iowa. ( Barcellos, WA; Maves, TJ, 1992)
"To clarify the site of action of epidural fentanyl, we compared the effects of epidural and intravenous fentanyl on the change in pressure pain threshold (PPT) and the minimum alveolar concentration (MAC) of halothane."5.07Segmental analgesic effect and reduction of halothane MAC from epidural fentanyl in humans. ( Inagaki, Y; Mashimo, T; Yoshiya, I, 1992)
"To evaluate the efficacy of opiate administration regimens, 32 patients with multiple rib fractures were prospectively randomized to receive either continuous epidural (ED) or continuous intravenous (IV) infusions of fentanyl."5.07Prospective evaluation of epidural and intravenous administration of fentanyl for pain control and restoration of ventilatory function following multiple rib fractures. ( Davis, JW; Hoyt, DB; Karagianes, TG; Mackersie, RC, 1991)
" It was the aim of this study to investigate the analgesic properties of nalbuphine as compared to those of fentanyl, in suppressing the hemodynamic responses due to endotracheal intubation and skin incision."5.06[Comparative clinical studies of the hemodynamic parameters by anesthesia combination with Nalbuphin (Nubain) and Fentanyl]. ( Dick, W; Heintz-Bamberg, D; Müller, H; Reiter, G, 1987)
"To systematically compare the efficacy and safety of sufentanil versus fentanyl for pain relief in labor involving combined spinal-epidural analgesia (CSEA), a systematic review and meta-analysis of randomized controlled trials targeting parturients requesting labor analgesia was conducted."5.05Sufentanil versus fentanyl for pain relief in labor involving combined spinal-epidural analgesia: a systematic review and meta-analysis of randomized controlled trials. ( Diao, Y; Geng, S; Huang, Z; Liu, S; Liu, Y; Shen, L; Su, X; Sun, J; Zhi, M, 2020)
"This study evaluated the analgesic efficacy of baclofen in relation to specific pain stimuli in 83 women (27 nulliparas and 56 multiparas) undergoing voluntary abortion (clamping of the cervix and dilatation and curettage)."5.05Double-blind placebo-controlled trial of baclofen, alone and in combination, in patients undergoing voluntary abortion. ( Bacchini, M; Battagliarin, G; Brambilla, C; Corli, O; Di Piazza, D; Grossi, E; Roma, G, 1984)
"To compare the incidence and severity of pain and myoclonus, 83 patients, premedicated with oral diazepam, received a double-blind intravenous injection of either droperidol 5 mg, fentanyl 0."5.05Pain and myoclonus during induction with etomidate. A double-blind, controlled evaluation of the influence of droperidol and fentanyl. ( Adam, AA; Giezen, J; Helmers, JH, 1981)
"Fentanyl citrate is administered intramuscularly at increasing doses to patients suffering from an intense pain in the facial or trigeminal nerves territory."5.05[Comparison between the analgesic effects of fentanyl and morphine in conscious man (author's transl)]. ( Cathelin, M; Malki, M; Viars, P; Vignes, R, 1980)
" Patients in whom anesthesia was induced with etomidate had a greater incidence of pain on injection and myoclonus and a lesser incidence of apnea than patients in whom anesthesia was induced with thiopental."5.05Etomidate versus thiopental for induction of anesthesia. ( Giese, JL; Nelissen, RH; Pace, NL; Stanley, TH; Stockham, RJ, 1985)
"Forty subjects rated the magnitude of painful electrical stimulation of tooth pulp before and after the intravenous administration of either fentanyl, a short-acting narcotic, or a saline placebo."5.04Narcotic analgesia: fentanyl reduces the intensity but not the unpleasantness of painful tooth pulp sensations. ( Dubner, R; Gracely, RH; McGrath, PA, 1979)
" The examined studies showed that dressing or cream containing morphine could potentially decrease pain, use of analgesics, and side effects associated with systemic opioid medications compared with control groups."4.98Efficacy and feasibility of opioids for burn analgesia: An evidence-based qualitative review of randomized controlled trials. ( He, GZ; Xu, XM; Yang, C, 2018)
"morphine, hydromorphone, fentanyl, trauma, acute pain, intravenous, opioid, pharmacokinetics, and pharmacodynamics."4.93Opioid Pharmacokinetics-Pharmacodynamics: Clinical Implications in Acute Pain Management in Trauma. ( Ensom, MH; MacKenzie, M; Zed, PJ, 2016)
"The objectives of this review were to assess the ability of both pharmacological and non-pharmacological interventions to reduce or eliminate the pain that accompanies rocuronium bromide administration."4.93Pharmacological and non-pharmacological interventions for reducing rocuronium bromide induced pain on injection in children and adults. ( Ali, Z; Kalaivani, M; Prabhakar, H; Singh, GP; Smith, MA, 2016)
" This rapid review, commissioned by the National Institute for Health Research, used standard Cochrane methodology to examine adverse effects of morphine, fentanyl, oxycodone, and codeine in cancer pain studies as a close approximation to possible effects in the dying patient."4.90Impact of morphine, fentanyl, oxycodone or codeine on patient consciousness, appetite and thirst when used to treat cancer pain. ( Derry, S; Moore, RA; Wiffen, PJ, 2014)
"To determine the analgesic efficacy of transdermal fentanyl for relief of cancer pain, and to assess the adverse events associated with the use of transdermal fentanyl for relief of cancer pain."4.89Transdermal fentanyl for cancer pain. ( Derry, S; Hadley, G; Moore, RA; Wiffen, PJ, 2013)
"Reports of trials of IN fentanyl in (ED) and prehospital treatment of pain were systematically sought using the PubMed database, Embase, Google scholar, the Cochrane database and the Cumulative Index to Nursing and Allied Health Literature."4.89Limited evidence for intranasal fentanyl in the emergency department and the prehospital setting--a systematic review. ( Dahl, JB; Hansen, MS, 2013)
"The findings indicate comparability of transdermal buprenorphine and transdermal fentanyl for pain measures with significantly fewer adverse events (nausea and treatment discontinuation due to adverse events) caused by transdermal buprenorphine."4.88Systematic review of efficacy and safety of buprenorphine versus fentanyl or morphine in patients with chronic moderate to severe pain. ( Aune, D; Hernandez, AV; Kleijnen, J; Misso, K; Riemsma, R; Truyers, C; Wolff, RF, 2012)
"To evaluate the long-term dosing, safety, and tolerability of fentanyl buccal tablet (FBT) in a large cohort of opioid-tolerant patients with chronic noncancer pain and breakthrough pain (BTP)."4.87Long-term dosing, safety, and tolerability of fentanyl buccal tablet in the management of noncancer-related breakthrough pain in opioid-tolerant patients. ( Janka, L; Nalamachu, SR; Narayana, A, 2011)
"Transdermal buprenorphine and fentanyl are now established for moderate-to-severe cancer pain."4.87Transdermal opioids for cancer pain. ( Ahmedzai, SH; Cachia, E, 2011)
"Oral transmucosal fentanyl citrate (OTFC) and fentanyl buccal tablets are the first medications developed specifically for the treatment of breakthrough pain in opioid-tolerant patients."4.87Fentanyl nasal spray for the treatment of cancer pain. ( Gouliamos, A; Mystakidou, K; Panagiotou, I, 2011)
"A short cut review was carried out to establish whether intranasal fentanyl is better than parenteral morphine for managing acute severe pain in children."4.87Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Bet 4: is intranasal fentanyl better than parenteral morphine for managing acute severe pain in children? ( Kusre, SR, 2011)
"To compare the efficacy of intranasal fentanyl spray (INFS), oral transmucosal fentanyl citrate (OTFC), fentanyl buccal tablet (FBT) and oral morphine (OM) for the treatment of breakthrough cancer pain (BTCP)."4.86Efficacy of intranasal fentanyl spray versus other opioids for breakthrough pain in cancer. ( Jansen, J; Lenre, M; Nolte, T; Stam, W; Vissers, D, 2010)
"Fentanyl is a potent opioid analgesic marketed for the treatment of stable intense chronic pain, particularly in the form of a transdermal patch."4.86Fentanyl patches: preventable overdose. ( , 2010)
"Previous meta-analysis suggested that transdermal fentanyl was not inferior to sustained-release oral morphine in treating moderate-severe cancer pain with less adverse effects."4.86Efficacy and adverse effects of transdermal fentanyl and sustained-release oral morphine in treating moderate-severe cancer pain in Chinese population: a systematic review and meta-analysis. ( Bi, ZF; Chen, DL; Jiang, ZM; Ma, W; Xie, DR; Yang, Q; Zhang, YD, 2010)
"Review key aspects of breakthrough pain management with fentanyl buccal tablet, with a focus on minimizing risk to optimize therapeutic outcomes."4.86Treatment of breakthrough pain with fentanyl buccal tablet in opioid-tolerant patients with chronic pain: appropriate patient selection and management. ( Fine, PG; Narayana, A; Passik, SD, 2010)
"Fentanyl, a short-acting synthetic pure opiate, offers an excellent option for the treatment of cancer and chronic pain."4.86Intranasal fentanyl: from pharmacokinetics and bioavailability to current treatment applications. ( Mystakidou, K; Panagiotou, I, 2010)
"Transdermal fentanyl patches first became available in the early 1990s and provided an innovative treatment for the management of cancer pain."4.85The role of transdermal fentanyl patches in the effective management of cancer pain. ( Gibbs, M, 2009)
"The safety of transdermal fentanyl (TF) in comparison with slow-release oral morphine (SROM) in moderate-severe pain was assessed."4.85Transdermal fentanyl as a front-line approach to moderate-severe pain: a meta-analysis of randomized clinical trials. ( Maltoni, M; Santelmo, C; Sartori, S; Scarpi, E; Tamburini, E; Tassinari, D; Tombesi, P, 2009)
"To evaluate the underlying pharmacology, safety, and misuse/abuse of transdermal fentanyl, one of the cornerstone pharmacotherapies for patients with chronic pain."4.85Transdermal fentanyl: pharmacology and toxicology. ( Nelson, L; Schwaner, R, 2009)
"In the present study, we demonstrated that repeated treatment with fentanyl, but not morphine or oxycodone, causes a rapid desensitization to its ability to block the hyperalgesia associated with the attenuation of mu-opioid receptor resensitization in mice in a chronic pain-like state."4.84[Difference in tolerance to anti-hyperalgesic effect and its molecular mechanisms between chronic treatment with morphine, fentanyl and oxycodone in a chronic pain-like state]. ( Hashimoto, S; Kuzumaki, N; Nakamura, A; Narita, M; Ozeki, A; Satoshi, I; Suzuki, T; Uezono, Y, 2008)
"To assess the adverse effects of transdermal opiates treating moderate-severe cancer pain in comparison with slow release oral morphine."4.84Adverse effects of transdermal opiates treating moderate-severe cancer pain in comparison to long-acting morphine: a meta-analysis and systematic review of the literature. ( Maltoni, M; Raffaeli, W; Sartori, S; Scarpi, E; Tamburini, E; Tassinari, D; Tombesi, P, 2008)
"Four studies (393 participants) met the inclusion criteria, all were concerned with the use of oral transmucosal fentanyl citrate (OTFC) in the management of breakthrough pain."4.83Opioids for the management of breakthrough (episodic) pain in cancer patients. ( Ribeiro, MD; Zeppetella, G, 2006)
"Transdermal buprenorphine has been assessed as a therapy for chronic cancer and non-cancer pain in both clinical and postmarketing surveillance studies."4.83Transdermal buprenorphine in cancer pain and palliative care. ( Sittl, R, 2006)
"The fentanyl buccal tablet (FBT) is a new formulation of fentanyl that uses an effervescent drug delivery system to enhance penetration across the buccal mucosa for the treatment of breakthrough pain in opioid-tolerant patients with cancer."4.83Fentanyl buccal tablet: in breakthrough pain in opioid-tolerant patients with cancer. ( Blick, SK; Wagstaff, AJ, 2006)
" We review the literature on intranasal administration of fentanyl, meperidine, diamorphine, and butorphanol to treat acute pain."4.83[Intranasal opioids for acute pain]. ( Añez Simón, C; Fuentes Baena, A; Rodríguez Pérez, A; Rull Bartomeu, M, 2006)
"Transdermal fentanyl is effective and well tolerated for the treatment of chronic pain caused by malignancy and non-malignant conditions when administered according to the manufacturer's recommendations."4.82Benefit-risk assessment of transdermal fentanyl for the treatment of chronic pain. ( Kornick, CA; Moryl, N; Obbens, EA; Payne, R; Santiago-Palma, J, 2003)
" Evidence presented in this review shows encouraging results following the administration of methadone, fentanyl or ketamine to patients with difficult pain problems."4.82Morphine is not the only analgesic in palliative care: literature review. ( Wootton, M, 2004)
"To evaluate effectiveness and safety information of transdermal fentanyl (TDF) (Duragesic/Durogesic) and sustained-release oral morphine (SRM) in cancer pain (CP) and chronic non-cancer pain (NCP), a pooled analysis was conducted on datasets of published, open label, uncontrolled (no comparator group) and randomised controlled (with SRM as comparator) studies of TDF."4.82Efficacy and safety of transdermal fentanyl and sustained-release oral morphine in patients with cancer and chronic non-cancer pain. ( Ahmedzai, SH; Allan, LG; Camacho, F; Clark, AJ; Horbay, GL; Richarz, U; Simpson, K, 2004)
" In pain studies, mainly the mu-opioidergic agonist [(11)C]-carfentanil and the unspecific opioid receptor antagonist [(11)C]-diprenorphine are applied."4.82What to learn from in vivo opioidergic brain imaging? ( Berthele, A; Boecker, H; Platzer, S; Sprenger, T; Tölle, TR, 2005)
"According to the World Health Organization (WHO) guidelines for patients with moderate or severe pain, morphine has been used as a "gold standard" treatment for cancer pain."4.82[Basic studies on cancer pain control]. ( Narita, M; Niikura, K; Ozaki, M; Suzuki, T; Yajima, Y, 2005)
"In this article, three aspects of recent issues in cancer pain management such as pain assessment, drowsiness with morphine, and problem in home care setting."4.81[Issues in cancer pain management]. ( Hoka, S; Matoba, M; Murakami, S, 2001)
"Transdermal fentanyl is a useful opioid-agonist for the treatment of moderate to severe chronic cancer pain."4.81Transdermal fentanyl: an updated review of its pharmacological properties and therapeutic efficacy in chronic cancer pain control. ( Muijsers, RB; Wagstaff, AJ, 2001)
"ALZA and Crescendo are developing E-TRANS fentanyl, an electrotransport system (ETS) delivery offentanyl that allows self-titration of the drug by the patient, for the potential management of acute pain."4.81E-TRANS fentanyl. ALZA. ( Mystakidou, K, 2002)
" Because all nurses must keep up to date on basic principles of assessment, pain management, and current pharmacologic and nonpharmacologic approaches to pain, AJN and Home Healthcare Nurse are proud to provide our readers with important information about pain management and a new medication recently approved by the FDA: oral transmucosal fentanyl citrate (Actiq)."4.80Managing breakthrough cancer pain: a new approach. ( Kedziera, P; Rhiner, M, 1999)
" The development of a transdermal fentanyl system provided an opportunity to add fentanyl to the armamentarium of strong opioids available for the treatment of cancer pain."4.79Transdermal fentanyl therapy: system design, pharmacokinetics and efficacy. ( Southam, MA, 1995)
"A new method of administration of an opioid was recently registered: fentanyl transdermal (brand name: Durogesic), intended particularly for the indication range 'pain in cancer'."4.79[Transdermal opioid administration: the pain plaster]. ( Sillevis Smitt, PA; Vecht, CJ, 1997)
"To review the use of transdermal fentanyl for the treatment of moderate to severe chronic pain."4.78Transdermal fentanyl. ( Lopez, JR; Yee, LY, 1992)
"Transdermal fentanyl appears to be a safe and practical alternative to short-acting analgesics in the treatment of cancer pain."4.78Transdermal fentanyl in cancer pain. ( Mosser, KH, 1992)
"The physicochemical properties, pharmacology, pharmacokinetics, serum concentrations and clinical effects, adverse effects and contraindications, and dosage of transdermally administered fentanyl are described, and clinical studies evaluating the use of a transdermal fentanyl system in the treatment of postoperative pain and chronic cancer-associated pain are reviewed."4.78Transdermally administered fentanyl for pain management. ( Calis, KA; Corso, DM; Kohler, DR, 1992)
" Treatment was administered using bicalutamide and leuprorelin acetate, while a transdermal fentanyl (TDF) was applied for pain relief."4.31Case Reports of Transdermal Fentanyl Patch Administration Difficulties in Cancer Patients with Excess Sweating. ( Ishii, H; Kanai, A; Kokubun, H; Tabata, KI, 2023)
"To determine if intranasal fentanyl is equally as effective as IV morphine for treating VOC-associated pain in adult SCD patients."4.31IF IM in a crisis: Intranasal fentanyl versus intravenous morphine in adult vaso-occlusive crisis. ( Assad, O; Brown, K; Melnitsky, L; Moses, J; Sherman, V; Zamora, R, 2023)
"Fentanyl, a highly potent synthetic opioid used in cancer and non-cancer pain, is approved for various routes of administration."4.31Abuse, dependence and withdrawal associated with fentanyl and the role of its (designated) route of administration: an analysis of spontaneous reports from Europe. ( Bantel, C; Hoffmann, F; Jobski, K, 2023)
"Fentanyl transdermal therapy is a suitable treatment for moderate-to-severe cancer-related pain."4.31An individualized digital twin of a patient for transdermal fentanyl therapy for chronic pain management. ( Bahrami, F; De Nys, K; Defraeye, T; Rossi, RM, 2023)
" Multiple demographic and psychosocial factors, as well as perhaps provider bias, play into both a patient's perception of pain and the dosage of fentanyl and midazolam they receive during abortion procedures."4.31The association of patient age, race, and demographic features on reported pain and sedation dosing during procedural abortion: A retrospective cohort study. ( Howard, M; Lee, J; Makar, E; Pace, L, 2023)
" Among those on methadone or buprenorphine (N = 108), multivariable logistic regression models examined the association between socio-demographics, MOUD type; and past-30-day use of heroin/fentanyl; crack; benzodiazepines; and pain medications."4.31Drug use patterns and factors related to the use and discontinuation of medications for opioid use disorder in the age of fentanyl: findings from a mixed-methods study of people who use drugs. ( Case, P; Green, TC; Hughto, JMW; Moyo, P; Palacios, WR; Rapisarda, SS; Silcox, J; Stopka, TJ; Tapper, A, 2023)
"Nalbuphine combined with ropivacaine in epidural block labor has a faster onset of analgesia and has a lower incidence of urinary retention than fentanyl combined with ropivacaine, and nalbuphine shortens the duration of the first and total stages of labor."4.31Effect of nalbuphine plus ropivacaine on vaginal labor in epidural analgesia. ( Cao, XS; He, QY; Liu, GH; Liu, LW; Ou, LC; Pang, Z; Wen, XJ; Yin, B, 2023)
"Fentanyl is a potent analgesic with a rapid onset and short half-life that make it a useful treatment for pain and a lethal drug of abuse."4.31Continuous fentanyl administration and spontaneous withdrawal decreases home cage wheel running in rats with and without hindpaw inflammation. ( Hilgendorf, TN; Kandasamy, R; Morgan, MM, 2023)
"The aim of this study was to assess the safety of fentanyl analgosedation during therapeutic hypothermia, by evaluating severe adverse effects and possible correlation with the neurodevelopmental outcome."4.12Fentanyl analgesia in asphyxiated newborns treated with therapeutic hypothermia. ( Bedetti, L; Berardi, A; Della Casa, E; Ferrari, F; Garetti, E; Guidotti, I; Iughetti, L; Lago, P; Lucaccioni, L; Lugli, L; Pugliese, M; Roversi, MF; Spada, C, 2022)
"This is a study that is based on network pharmacology, focusing on the pharmacological mechanism of fentanyl in easing pain."4.12Study on the Mechanism of Fentanyl in Pain Treatment Based on Network Pharmacology. ( Bi, J; Wan, H; Wang, S; Zhao, J; Zhao, W; Zhou, S, 2022)
"Transdermal fentanyl patches are an effective alternative to the sustained release of oral morphine for chronic pain management."4.12Predicting transdermal fentanyl delivery using physics-based simulations for tailored therapy based on the age. ( Bahrami, F; Defraeye, T; Rossi, RM, 2022)
" There was a significant decrease in propofol and fentanyl utilization from 24 hours pretracheostomy to 24 hours posttracheostomy in both dose and number of patients receiving these continuous intravenous medications."4.12Tracheostomy decreases continuous analgesia and sedation requirements. ( Droege, CA; Elson, NC; Goodman, MD; Hayes, HV; Nomellini, V; Pritts, TA; Salvator, A; Singer, KE; Wallen, TE, 2022)
"Positive responses to a fentanyl vaccine were found along with appreciation for the complexity of a vaccine strategy to prevent OD in the setting of pain and uncertain durability."4.12Acceptability of a Fentanyl Vaccine to Prevent Opioid Overdose and Need for Personalized Decision-Making. ( Blakemore, LM; Cox, R; Dowling, DJ; Kossowsky, J; Levy, O; Levy, S; Needles, EW; Weitzman, ER, 2022)
"Intranasal fentanyl offers a means for safe and effective pain management in austere environments."4.12Intranasal Fentanyl for On-the-Hill Analgesia by Ski Patrol. ( Callas, PW; Lynch, TV; Peterson, TD; Schlein, SM, 2022)
"Methoxyflurane is commonly used by ambulance services to treat pain in pregnant women in WA."4.12Prevalence and Perinatal Outcomes Following In Utero Exposure to Prehospital Emergency Methoxyflurane: A 17-Year Retrospective Cohort Study. ( Kelty, E; Murray, K; Preen, D; Pyle, A; Sanfilippo, F, 2022)
" His pain and agitation were difficult to manage but improved after he received ketamine."4.12Suspected opioid-induced hyperalgesia in an infant following surgery: A case report. ( Efune, PN; Rebstock, SE, 2022)
"Opioids like fentanyl remain the mainstay treatment for chronic pain."4.12Sex-specific role of the circadian transcription factor NPAS2 in opioid tolerance, withdrawal and analgesia. ( Barko, K; Logan, RW; Puig, S; Seney, ML; Shelton, MA, 2022)
"It is recommended not to use transdermal fentanyl (Fe) patches (TFP) in cancer cachexia but TFP may be the only available option for pain."4.12Transdermal fentanyl to parenteral morphine route switch and drug rotation in refractory cancer cachexia. ( Alabdullateef, SH; Almashiakhi, M; Alsirafy, SA; Elyamany, AM; Hassan, AD, 2022)
"During the preliminary experiment, all fentanyl concentrations reached the minimum effective concentration (MEC) extrapolated in pigs (fentanylemia ≥0."4.02Long-Term Analgesia following a Single Application of Fentanyl Transdermal Solution in Pigs. ( Allorge, D; Chetboun, M; Gaulier, JM; Goutchtat, R; Hubert, T; Pattou, F; Wiart, JF, 2021)
"Nebulized fentanyl is well established for analgesia but its use for dyspnea requires further investigation."3.96Nebulized Fentanyl for Dyspnea: A Retrospective Chart Review. ( Cain, J; Coyne, PJ; Dulin, JD; Higgins, EA; Miller, MM; Overstreet, AN; Vaughan, L; Young, AM, 2020)
"Sprague-Dawley rats (11-13 weeks) were randomly assigned to control (saline vehicle), fentanyl, or ketamine-treated groups with or without hemorrhage (n = 8 or 9 for each group)."3.96Fentanyl impairs but ketamine preserves the microcirculatory response to hemorrhage. ( Calderon, AS; Hinojosa-Laborde, C; Klemcke, HG; Ryan, KL; Scott, LL; Xiang, L, 2020)
"Fentanyl has been associated with many drug overdose deaths; its presence in many street drugs has been postulated to be increasing."3.96Correlation of Fentanyl Positive Drug Screens with Other Medications in Patients from Pain, Rehabilitation and Behavioral Programs. ( Greg Ackerman, RT; Krock, K; Nickley, J; Pesce, A; Tran, K, 2020)
"4-Anilidopiperidine class of synthetic opioid analgesics, with it's representative fentanyl, are by far the most potent and clinically significant for the treatment of the severe chronic and surgical pain."3.96Synthesis and pharmacological evaluation of novel cis and trans 3-substituted anilidopiperidines. ( Ivanović, MD; Jevtić, II; Kostić-Rajačić, SV; Savić Vujović, K; Srebro, D; Vučković, S, 2020)
"Transdermal fentanyl is a well-used and highly effective form of opioid analgesia for patients suffering with severe chronic pain."3.96Fentanyl patches: Use and Misuse. ( Langford, NJ, 2020)
"This review evaluates current recommendations for pain management in chronic kidney disease (CKD) and end-stage kidney disease (ESKD) with a specific focus on evidence for opioid analgesia, including the partial agonist, buprenorphine."3.96Pain management in patients with chronic kidney disease and end-stage kidney disease. ( Dember, LM; Jhamb, M; Liebschutz, J; Roy, PJ; Weltman, M, 2020)
"Ketorolac is a reasonable non-narcotic alternative to fentanyl which provides equal pain control and does not increase tube occlusion rates."3.96Perioperative pain control and tympanostomy tube outcomes. ( Adil, E; Irace, AL; Kawai, K; Leung, P; Riley, B, 2020)
" However, its analgesic efficacy remains uncertain for painful procedures; therefore, a combination with intranasal fentanyl (INF), an opioid, was suggested."3.91Nitrous Oxide 70% for Procedural Analgosedation in a Pediatric Emergency Department-With or Without Intranasal Fentanyl? ( Landolt, MA; Seiler, M; Staubli, G, 2019)
"We report the case of a 60 year old patient on chronic Intrathecal combined fentanyl and Bupivacaine who had worsening pain with increasing doses and improved after weaning off intrathecal opioids."3.91Opioid Induced Hyperalgesia with Intrathecal Infusion of High-Dose Fentanyl. ( Acquadro, MA; Cheng, Y; Farah, F; Gerges, FJ; Kalaydjian, A, 2019)
"Low prevalence of active prescriptions for opioids for pain at the time of overdose suggests that opioid prescribing plays a limited short-term impact in the current fentanyl-related crisis of overdoses."3.91Patterns and history of prescription drug use among opioid-related drug overdose cases in British Columbia, Canada, 2015-2016. ( Chong, M; Crabtree, A; Mill, C; Park, M; Schütz, CG; Smolina, K; Zhao, B, 2019)
"To test the effectiveness of a premedication protocol using intravenous bolus of 100 μg fentanyl to reduce pain associated with femoral artery closure device placement for neuro-endovascular procedures."3.91Effectiveness of premedication protocol using intravenous fentanyl to reduce pain associated with femoral artery closure device placement. ( Naseem, N; Qureshi, AI; Saleem, MA; Wallery, SS, 2019)
" Fentanyl (77%) and hydromorphone (48%) were the most common intravenous opioids used to manage pain."3.91Current practice and perceptions regarding pain, agitation and delirium management in patients receiving venovenous extracorporeal membrane oxygenation. ( Abrams, D; Agerstrand, C; Brodie, D; Dzierba, AL; Madahar, P; Muir, J, 2019)
" Even after multiple testing with Bonferroni adjustments, an increase in the analgesic effect of fentanyl in the cold pressor-induced pain test was significantly associated with a greater number of the A allele of the rs7583431 SNP (linear regression, P = ."3.88Association between the rs7583431 single nucleotide polymorphism close to the activating transcription factor 2 gene and the analgesic effect of fentanyl in the cold pain test. ( Aoki, Y; Fukuda, KI; Hasegawa, J; Hayashida, M; Ichinohe, T; Ikeda, K; Kasai, S; Koukita, Y; Nishizawa, D; Takahashi, K; Yoshida, K, 2018)
" Fentanyl as a second choice is mainly reserved for situations of stable pain."3.88Opioid Prescribing Behavior in Long-Term Geriatric Care in the Netherlands. ( Janssen, DJA; Martens, MJM; Schols, JMGA; van den Beuken-van Everdingen, MHJ, 2018)
" Fentanyl, midazolam, and dexmedetomidine were the first choices of agents for analgesic, sedation, and delirium treatment."3.85A National Multicenter Survey on Management of Pain, Agitation, and Delirium in Intensive Care Units in China. ( Hu, B; Li, JG; Peng, ZY; Rao, X; Wang, J; Zhou, WH, 2017)
"Our aim was to evaluate a nurse-initiated pain-management protocol in adult patients with traumatic injuries in the short and in the long term, utilizing fentanyl for severe pain."3.85Emergency Department Pain Management in Adult Patients With Traumatic Injuries Before and After Implementation of a Nurse-Initiated Pain Treatment Protocol Utilizing Fentanyl for Severe Pain. ( Goslings, JC; Hollmann, MW; Lirk, P; Ridderikhof, ML; Schep, NW; Schyns, FJ, 2017)
"To assess the effectiveness of nebulized fentanyl used for analgesia in renal colic."3.85A retrospective analysis of nebulized versus intravenous fentanyl for renal colic. ( Aygun, A; Bekar, O; Cicek, M; Erdem, E; Imamoglu, M; Karaca, Y; Sahin, A; Tatli, O; Turedi, S; Turkmen, S, 2017)
"Phenylpiperidines are a chemical class of drugs with a phenyl moiety directly attached to piperidine."3.85Current Concepts of Phenylpiperidine Derivatives Use in the Treatment of Acute and Chronic Pain. ( Choi, S; Elbaridi, N; Kaye, AD; Urman, RD, 2017)
"To explore analgesic effects of fentanyl and butorphanol on incisional pain in rats and to investigate the pharmacological mechanism of combination."3.83Analgesic effect and pharmacological mechanism of fentanyl and butorphanol in a rat model of incisional pain. ( Chen, Q; Li, P; Liu, GL; Shang, Y; Xu, Y, 2016)
"Prediction of the response to transdermal fentanyl (FENtd) before its use for chronic pain is desirable."3.83Response to intravenous fentanyl infusion predicts subsequent response to transdermal fentanyl. ( Hayashi, N; Kanai, A; Nagahara, Y; Okamoto, H; Suzuki, A, 2016)
"We collected OFL and plasma samples from 64 cancer patients on controlled-release (CR) oral morphine, CR oral oxycodone, or transdermal (TD) fentanyl for pain."3.81Opioid Concentrations in Oral Fluid and Plasma in Cancer Patients With Pain. ( Gunnar, T; Heiskanen, T; Kalso, EA; Langel, K; Lillsunde, P, 2015)
"Only fentanyl+midazolam significantly attenuated both the clinical pain score and the increase in blood glucose."3.81Effect of premedication regimen on infant pain and stress response to endotracheal intubation. ( Caldwell, CD; Watterberg, KL, 2015)
"Little is known about the efficacy of low-dose transdermal fentanyl (TDF) patches in opioid-naïve patients with moderate-to-severe cancer pain."3.81The efficacy of low-dose transdermal fentanyl in opioid-naïve cancer patients with moderate-to-severe pain. ( Hwang, IG; Kang, JH; Kim, JH; Kim, WS; Lee, HR; Lee, HY; Lee, KE; Oh, SY; Park, K; Park, SH; Park, YS; Song, SY, 2015)
"This study aims to determine whether a pathway designed to facilitate the use of intranasal (IN) fentanyl for long-bone fractures will expedite the delivery of pain medication, decrease the total length of emergency department (ED) stay, and provide faster analgesia compared with intravenous (IV) morphine."3.81Expedited Delivery of Pain Medication for Long-Bone Fractures Using an Intranasal Fentanyl Clinical Pathway. ( Erikson Ramirez, D; Frazier, SB; Perkins, AM; Schacherer, NM, 2015)
" Oxycodone and fentanyl, in relation to the symptoms studied, seem to be safe as used and titrated in routine cancer pain care."3.81Renal function and symptoms/adverse effects in opioid-treated patients with cancer. ( Christrup, L; Dale, O; Davies, A; Ekholm, O; Kaasa, S; Klepstad, P; Kurita, GP; Lundström, S; Sjøgren, P, 2015)
"Intranasal fentanyl seems to be efficient for analgesia in adult patients with renal colic."3.81Does intranasal fentanyl provide efficient analgesia for renal colic in adults? ( Bakkali, H; Belkouch, A; Belyamani, L; Chouaib, N; Elbouti, A; Rafai, M; Sirbou, R; Zidouh, S, 2015)
"Common adverse symptoms of cancer and chemotherapy are a major health burden; chief among these is pain, with opioids including transdermal fentanyl the mainstay of treatment."3.81Innate Immune Signalling Genetics of Pain, Cognitive Dysfunction and Sickness Symptoms in Cancer Pain Patients Treated with Transdermal Fentanyl. ( Barratt, DT; Dale, O; Kaasa, S; Klepstad, P; Somogyi, AA, 2015)
"Fentanyl is widely used to relieve cancer pain."3.81Saliva versus Plasma for Pharmacokinetic and Pharmacodynamic Studies of Fentanyl in Patients with Cancer. ( Bista, SR; Good, P; Hardy, J; Haywood, A; Lobb, M; Norris, R; Tapuni, A, 2015)
"Pain management with transdermal opioids is a useful choice in light of longer duration of action, being not affected by oral intake, and with less adverse effect Recently, transdermal fentanyl and buprenorphine are permitted for musculoskeletal non-malignant pain as a new indication."3.81[Transdermal System-Buprenorphine and Fentanyl]. ( Sakurai, H, 2015)
"Fentanyl citrate buccal tablets are indicated for the treatment of breakthrough pain (BTP) in cancer, in adults who are receiving maintenance opioid therapy for chronic cancer pain."3.80Utilization of fentanyl buccal tablets in England: exploring off-label use reported in a cohort study. ( Al-Shukri, M; Fogg, C; Layton, D; Osborne, V; Shakir, SA, 2014)
"Antinociceptive effect of narcotic analgesics, fentanyl, oxycodone and methadone in inflammatory pain state was described in the von Frey filament test using the complete Freund's adjuvant (CFA)-induced mouse inflammatory pain model."3.80Differential alternation of the antinociceptive effect of narcotic analgesics on the inflammatory pain state. ( Aoki, Y; Mizoguchi, H; Sakurada, S; Sakurada, T; Watanabe, C, 2014)
" infusion of fentanyl in patients with hepatocellular carcinoma (HCC) treated by RFA."3.80Pain control in patients with hepatocellular carcinoma treated by percutaneous radiofrequency ablation: comparison of the efficacy of one-shot and continuous intravenous fentanyl delivery. ( Ikeda, O; Inoue, S; Kawanaka, K; Nakasone, Y; Tamura, Y; Yamashita, Y; Yokoyama, K, 2014)
"This study aimed to investigate whether CYP3A4/5 genetic variants, together with clinical and patient factors, influence serum fentanyl and norfentanyl concentrations and their ratio in cancer pain patients receiving transdermal fentanyl."3.80Genetic, pathological and physiological determinants of transdermal fentanyl pharmacokinetics in 620 cancer patients of the EPOS study. ( Bandak, B; Barratt, DT; Christrup, LL; Dale, O; Kaasa, S; Klepstad, P; Somogyi, AA; Tuke, J, 2014)
"It is unknown whether nutritional status influences pain intensity in cancer patients receiving a transdermal fentanyl patch (FP)."3.80A retrospective study on the influence of nutritional status on pain management in cancer patients using the transdermal fentanyl patch. ( Chiba, T; Kimura, Y; Kudo, K; Tairabune, T; Takahashi, H; Takahashi, K; Wakabayashi, G, 2014)
"This study evaluated the efficacy, safety, and quality of life (QoL) measure of transdermal fentanyl (TDF) for moderate-to-severe pain due to oral mucositis caused by chemoradiotherapy in patients with advanced nasopharyngeal carcinoma (NPC)."3.80Transdermal fentanyl for pain due to chemoradiotherapy-induced oral mucositis in nasopharyngeal cancer patients: evaluating efficacy, safety, and improvement in quality of life. ( Feng, HX; Guo, SP; He, ZY; Li, FY; Sun, JY; Wu, SG; Wu, YJ; Zhou, J, 2014)
"Cold pain sensitivity and analgesic effects of fentanyl were related to the SNP and haplotypes of the P2RX7 gene."3.80Haplotypes of P2RX7 gene polymorphisms are associated with both cold pain sensitivity and analgesic effect of fentanyl. ( Fukuda, K; Hasegawa, J; Hayashida, M; Ide, S; Ikeda, K; Kasai, S; Minami, M; Nishizawa, D, 2014)
"Morphine, oxycodone, and fentanyl are commonly used to control cancer pain."3.80Influence of serum albumin levels during opioid rotation from morphine or oxycodone to fentanyl for cancer pain. ( Arakawa, Y; Fukuura, K; Futamura, A; Hayashi, T; Higashiguchi, T; Ikehata, S; Kuki, R; Makihara, T; Matsuzaki, H; Mori, N; Takahashi, H; Yamadaa, S; Yasuda, K, 2014)
"Palliative care physicians are accustomed to using transdermal fentanyl patch for cancer pain control but not so familiar with its intravenous administration."3.80Use of intravenous fentanyl against morphine tolerance in breakthrough cancer pain: a case series and literature review. ( Bruera, E; Hwang, IC; Park, SM, 2014)
"Utility functions based on fentanyl's experimental effects on respiration and pain relief were successfully constructed."3.79Fentanyl utility function: a risk-benefit composite of pain relief and breathing responses. ( Aarts, L; Boom, M; Dahan, A; Fussen, R; Groeneveld, GJ; Hay, J; Neukirchen, M; Olofsen, E; Sarton, E, 2013)
"Fentanyl pectin nasal spray is a novel intranasal formulation for the management of breakthrough cancer pain in patients taking and tolerant to opioids for persistent cancer pain."3.79Fentanyl pectin nasal spray: a novel intranasal delivery method for the treatment of breakthrough cancer pain. ( Bulloch, MN; Hutchison, AM, 2013)
") administration of the central analgesics fentanyl and dipyrone, and also mediators of pain such as L-glutamate, CCK, ATP, phenylephine and analgesic mediator adenosine, slightly penetrating in CNS, in the minimum effective dose (MED) cause the maximal analgesic effect in the tail flick test in rats."3.78[Peripheral acting mediators pain and analgesia potentiate the central analgesic action of fentanyl and dipyrone]. ( Gmiro, VE; Serdiuk, SE, 2012)
"Determining the appropriate dose of transdermal fentanyl (TDF) for the alleviation of cancer pain requires determining the factors causing variations in serum fentanyl concentration after TDF treatment."3.78Population pharmacokinetics of transdermal fentanyl in patients with cancer-related pain. ( Ebinuma, K; Kokubun, H; Matoba, M; Takayanagi, R; Yago, K; Yamada, Y, 2012)
"We report our experiences of 2 cases of successful pain management at home by using opioid rotation from a fentanyl preparation to a continuous subcutaneous injection of morphine hydrochloride, at a dose less than the equivalent dose based on the conversion table."3.78[2 cases of successful symptom management at home by using opioid rotation from a fentanyl preparation to a continuous subcutaneous injection of morphine hydrochloride, at a dose less than the equivalent dose based on the conversion table]. ( Ishii, N; Koyanagi, J; Miyamori, T; Murase, J; Nishi, T; Saka, S; Sato, M; Yamagishi, T, 2012)
"This study sought to prospectively assess fentanyl safety in a large out-of-hospital group, to identify variables associated with post-fentanyl hypotension (HN; systolic blood pressure [SBP] < 90) or hypoxemia (HX; SpO(2) < 90%)."3.77Fentanyl in the out-of-hospital setting: variables associated with hypotension and hypoxemia. ( Krauss, WC; Shah, S; Thomas, SH, 2011)
"This study analysed the analgesic effect and changes in vital signs associated with administration of inhaled Methoxyflurane (MTX) and/or intranasal Fentanyl (INF) for prehospital management of visceral pain."3.77Inhaled methoxyflurane and intranasal fentanyl for prehospital management of visceral pain in an Australian ambulance service. ( Brightwell, R; Johnston, S; Thompson, JA; Wilkes, GJ; Ziman, M, 2011)
"We experienced a patient with an ileal artificial anus who suffered from abdominal pain caused by peritoneal dissemination of ovarian cancer, for which slow-release oxycodone was ineffective, but fentanyl patch proved effective."3.77[A case of pain management using transdermal fentanyl patches for peritoneal carcinomatosis in a patient with small intestine stoma]. ( Iwazaki, M; Masuda, R; Mikami, M; Nishiumi, N; Saito, Y; Tokuda, Y; Yoshino, K, 2011)
" Compared with other opioids, low-dose fentanyl has been suggested to produce milder side effects such as nausea, constipation, and somnolence."3.77[Direct low-dose fentanyl patch (2.1mg) introduction for opioid naïve outpatients with cancer pain]. ( Fujita, S; Fukae, M; Hata, A; Iwamori, S; Kaji, R; Katakami, N; Masuda, Y; Mifune, Y; Nanjo, S; Orita, H; Otsuka, K; Yamatani, T, 2011)
"To identify predictive factors requiring high-dose transdermal fentanyl in opioid switching from oral morphine or oxycodone to transdermal fentanyl in patients with cancer pain."3.77Factors predicting requirement of high-dose transdermal fentanyl in opioid switching from oral morphine or oxycodone in patients with cancer pain. ( Fujimoto, S; Hosokawa, T; Kanbayashi, Y; Konishi, H; Miki, T; Okamoto, K; Otsuji, E; Takagi, T; Taniwaki, M; Yoshikawa, T, 2011)
"The three-cycle fentanyl patch system provided a stable plasma fentanyl concentration and excellent pain relief and should be considered for pain control in cancer patients."3.77Three-cycle fentanyl patch system contributes to stable control of plasma fentanyl concentration in gynecologic cancer pain patients. ( Kanamori, C; Kanamori, T; Kanzaki, H; Tanaka, Y, 2011)
"The FDA has approved a nasal spray formulation of fentanyl (Lazanda-Archimedes) for management of breakthrough pain in adult cancer patients who are already receiving and are tolerant to opioid therapy."3.77Fentanyl nasal spray (Lazanda) for pain. ( , 2011)
"The aim of this study is to investigate cancer patients' response and side effects associated with transdermal therapeutic fentanyl (TTS-F), whose pain was hardly controlled by nonweak/weak opioids in Taiwan."3.76The use of transdermal fentanyl in cancer pain--a compliance study of outpatients in Taiwan. ( Chen, YJ; Chiou, TJ; Hung, CJ; Liu, CY; Su, YC; Tang, Y; Tzeng, WF; Weng, YC, 2010)
"Fentanyl is a potent analgesic drug in relieving chronic pain in patients."3.76Development of a liquid chromatography-isotope dilution mass spectrometry method for quantification of fentanyl in human plasma. ( Gui, YZ; Jia, JY; Li, SJ; Liu, GY; Lu, C; Shi, XJ; Yu, C, 2010)
" When fentanyl was subsequently administered to treat her pain, the stridor resolved."3.76Treating stridor with opioids: a challenging case of paradoxical vocal cord movement. ( Neustein, SM; Rosenblatt, MA; Taitt-Wynter, LM, 2010)
" We treated a 50s female with pain and dyspnea from bone metastasis and lymphangitis carcinomatosa after surgery for NSCLC in whom the optimal dosages of transdermal fentanyl (Durotep Patch) were determined by titration with fentanyl injection, and oxycodone hydrochloride (OxyContin) in a short period."3.76[Successful management of a patient with pain and dyspnea from bone metastasis and lymphangitis carcinomatosa after surgery for non-small cell lung cancer (NSCLC) in whom optimal dosages of transdermal fentanyl were determined by titration with fentanyl i ( Eguchi, K; Gika, M; Inoue, Y; Izawa, N; Nakayama, M; Takeuchi, K, 2010)
"For 20 hospitalized patients with cancer pain that could not be controlled by NSAIDs, the fentanyl transdermal patch (1."3.76Evaluation of analgesic effect and safety of fentanyl transdermal patch for cancer pain as the first line. ( Hoya, Y; Okamoto, T; Yanaga, K, 2010)
" Here, by using a chronic inflammation model, namely subplantar injection of Complete Freund's adjuvant, we show a peripheral synergistic interaction between the histamine H(3) receptor agonist R-(alpha)-methylhistamine and fentanyl on the inhibition of thermal hyperalgesia and of peripheral substance P accumulation."3.76Histamine H3 receptor activation potentiates peripheral opioid-mediated antinociception: substance P role in peripheral inflammation in mice. ( Ciruela, F; Fernández-Dueñas, V; Gandía, J; Planas, E; Poveda, R; Sánchez, S, 2010)
"We conducted an online English survey of Canadian neonatologists using Survey Monkey, whereby they answered questions about the frequency and pattern of use of opioids, and specifically, of morphine and fentanyl, for ventilated and spontaneously breathing infants undergoing selected painful medical procedures."3.76Canadian neonatologist practices regarding opioid use in ventilated and spontaneously breathing infants undergoing medical procedures. ( McNair, C; Pulleyblank, R; Shah, V; Stephens, D; Taddio, A, 2010)
"We describe here a patient who obtained a good analgesic effect with high-dose fentanyl patches for controlling cancer pain."3.76High-dose fentanyl patch for cancer pain of a patient with cholangiocarcinoma. ( Jang, HJ; Jung, JY; Kim, HS; Kim, JH; Kim, M; Shin, YC; Sung, CW, 2010)
" IV fentanyl PCA was used for pain control in 16 patients with lower extremity, neuropathic/ischaemic pain, scheduled for major lower extremity amputation."3.76Case report. Intravenous fentanyl patient-controlled analgesia for perioperative treatment of neuropathic/ischaemic pain in haemodialysis patients: a case series. ( Aretha, D; Filos, KS; Karanikolas, M; Kiekkas, P; Monantera, G; Tsolakis, I, 2010)
"The aim of this study was to evaluate the equianalgesic ratio of transdermal buprenorphine (TD BUP) with oral morphine and TD fentanyl in a sample of consecutive cancer patients receiving stable doses of 120-240 mg of oral morphine or 50-100 microg of TD fentanyl, reporting adequate pain and symptom control."3.75Equipotent doses to switch from high doses of opioids to transdermal buprenorphine. ( Casuccio, A; Giarratano, A; Mercadante, S; Tirelli, W, 2009)
"Factors that influenced the choice of dose of oral transmucosal fentanyl at the time of burns dressing change were investigated in a prospective study."3.75Factors in the choice of oral transmucosal fentanyl citrate dose for adult burns dressings. ( Hanafiah, Z; Holdcroft, A; Shah, H; Smythe, J; Williams, GJ, 2009)
" The following data points were collected before and after each naloxone dose; blood pressure, heart rate, respiratory rate, RASS score, pain assessment score (recorded as present or absent), midazolam dose, propofol dose and fentanyl dose."3.75Safety of enteral naloxone for the reversal of opiate-induced constipation in the intensive care unit. ( Arpino, PA; Thompson, BT, 2009)
"This report describes an infant who was born to a mother with chronic pain treated with fentanyl 100 microg/h transdermal patch throughout her pregnancy and during lactation."3.75Fentanyl transdermal analgesia during pregnancy and lactation. ( Cohen, RS, 2009)
"We report on a 64-year-old patient in whom fentanyl therapy was found to be responsible for the induction of secondary adrenal insufficiency as clearly demonstrated by re-exposure."3.75Secondary adrenal insufficiency due to opiate therapy - another differential diagnosis worth consideration. ( Brändle, M; Greminger, P; Schimke, KE, 2009)
"Given preemptively, nefopam may be effective at improving postoperative pain management and at reducing the risk of developing postoperative chronic pain, because the drug has both analgesic and antihyperalgesic properties."3.75Long-term pain vulnerability after surgery in rats: prevention by nefopam, an analgesic with antihyperalgesic properties. ( Chateauraynaud, J; Laboureyras, E; Richebé, P; Simonnet, G, 2009)
"Transdermal fentanyl (Duragesic, and others) offers a convenient delivery system for patients with chronic pain but it has some drawbacks."3.75In brief: heat and transdermal fentanyl. ( , 2009)
"Morphine, oxycodone, and fentanyl are clinically prescribed drugs for the management of severe pain."3.75Morphine, oxycodone, and fentanyl exhibit different analgesic profiles in mouse pain models. ( Hasegawa, M; Ito, H; Kanemasa, T; Kato, A; Kihara, T; Koike, K; Masuno, K; Matsumoto, M; Matsushima, S; Minami, K; Miyoshi, T; Nakamura, A; Narita, M; Orita, S; Shimada, S; Suzuki, T; Tomii, T; Torii, M, 2009)
"Fentanyl transdermal system is indicated for the management of persistent, moderate-to-severe chronic pain that requires continuous opioid administration for an extended period of time and cannot be managed by other means such as nonsteroidal analgesics, opioid combination products, or immediate-release opioids."3.75Reducing patient harm with the use of fentanyl transdermal system. ( Gaunt, MJ; Grissinger, M, 2009)
"Although fentanyl patches (FP) designed to sustain plasma fentanyl concentrations for 3 days are used in many patients for continuous relief of moderate to severe cancer pain, there are some cases in which effective pain relief is sustained less than for 3 days, and in which plasma fentanyl concentrations rapidly decrease at the third day after the application."3.74[Measurement of amount of fentanyl remaining in used patches: investigation of clinical factors affecting the remaining amounts in 4 patients]. ( Iguchi, H; Kojima, M; Ohta, T; Yamamoto, K, 2008)
"The fentanyl transdermal matrix patch is approved in Japan for the management of moderate to severe cancer-related pain in adults."3.74Fentanyl transdermal matrix patch (Durotep MT patch; Durogesic DTrans; Durogesic SMAT): in adults with cancer-related pain. ( Hoy, SM; Keating, GM, 2008)
"Fentanyl is a potent synthetic narcotic analgesic administered in the form of a transdermal patch for the management of chronic pain."3.74LC-MS/MS analysis of fentanyl and norfentanyl in a fatality due to application of multiple Durogesic transdermal therapeutic systems. ( Coopman, V; Cordonnier, J; Pien, K; Van Varenbergh, D, 2007)
"To evaluate the efficacy and safety of fentanyl administered by PCA in children with cancer pain."3.74Safety and efficacy of fentanyl administered by patient controlled analgesia in children with cancer pain. ( Barone, G; Chiaretti, A; Lazzareschi, I; Liotti, L; Riccardi, R; Ruggiero, A, 2007)
" The median VAS scores of all patients were above 4 (moderate to severe pain) before the administration of transdermal fentanyl."3.74[Transdermal fentanyl in treating severe painful mucositis caused by autologous hematopoietic stem cell transplantation]. ( Bu, Q; Cai, QQ; Gao, Y; Huang, HQ; Lin, XB; Peng, YL; Wang, BF, 2007)
" Patients with far advanced cancer often suffer from sweating and cachexia, which may have negative effects on the absorption of transdermal fentanyl."3.74Clinical experience with transdermal and orally administered opioids in palliative care patients--a retrospective study. ( Clemens, KE; Klaschik, E, 2007)
"The implementation of a fentanyl-based pain management protocol resulted in a marked reduction in time to initial analgesia among trauma patients."3.74A fentanyl-based pain management protocol provides early analgesia for adult trauma patients. ( Curtis, KM; Fanciullo, G; Henriques, HF; Reynolds, CM; Suber, F, 2007)
" Here we show that rats with chronic morphine treatment do not develop signs of tolerance at peripheral mu-opioid receptors (micro-receptors) in the presence of painful CFA-induced paw inflammation."3.74Chronic morphine use does not induce peripheral tolerance in a rat model of inflammatory pain. ( Binder, W; Brack, A; Fischer, O; Mousa, SA; Rittner, HL; Schäfer, M; Shakibaei, M; Shaqura, M; Stein, C; Urban, F; Zöllner, C, 2008)
"Indigent patients without prescription coverage trended toward reporting more cancer pain, received lower doses of transdermal fentanyl, and trended to lower adherence to pain regimens due to financial reasons."3.74Influence of prescription benefits on reported pain in cancer patients. ( Amadio, WJ; Bryan, M; De La Rosa, N; Hill, AM; Wieder, R, 2008)
"The experimental setup consisted of a randomized block design with four experimental groups: two light (3/4) minimum alveolar concentration (MAC) isoflurane anesthesia groups (unstimulated/NIWR-stimulated) and two NIWR-stimulated surgical anesthesia groups (1(1/2) MAC isoflurane anesthesia and (3/4) MAC isoflurane anesthesia combined with fentanyl 400-600 microg x kg(-1) x h(-1))."3.74Suppression of noxious-induced c-fos expression in the rat lumbar spinal cord by isoflurane alone or combined with fentanyl. ( Nguyen, NK; Ritskes-Hoitinga, M; Sommers, MG; van Egmond, J; Veening, JG; Vissers, KC, 2008)
"About 61% of the patients suffered from non-cancer pain and 60% used other opioids before start of TTS fentanyl."3.73Utilisation pattern of fentanyl transdermal system in The Netherlands. ( Breekveldt-Postma, NS; Herings, RM; Penning-van Beest, FJ, 2005)
"This retrospective study identified patients with cancer and noncancer pain who had received > or =1 prescription for fentanyl TD or buprenorphine TD (the all-patients groups) from the German IMS Disease Analyzer-mediplus database, which contains all relevant data concerning drug prescriptions from 400 practices in Germany."3.73Equipotent doses of transdermal fentanyl and transdermal buprenorphine in patients with cancer and noncancer pain: results of a retrospective cohort study. ( Likar, R; Nautrup, BP; Sittl, R, 2005)
"The present study was conducted to evaluate the pain development and bone destruction during bone cancer growth in a murine model of bone cancer pain and to evaluate the analgesic efficacy of fentanyl, sufentanil, and morphine in this model."3.73Evaluation of pain-related behavior, bone destruction and effectiveness of fentanyl, sufentanil, and morphine in a murine model of cancer pain. ( El Mouedden, M; Meert, TF, 2005)
"The purpose of this study was to compare changes in dosages of transdermal (TD) fentanyl and TD buprenorphine in patients with cancer and non-cancer pain."3.73Changes in the prescribed daily doses of transdermal fentanyl and transdermal buprenorphine during treatment of patients with cancer and noncancer pain in Germany: results of a retrospective cohort study. ( Nautrup, BP; Nuijten, M; Sittl, R, 2005)
"The current study was performed to evaluate the effectiveness and safety of transdermal therapeutic system (TTS) fentanyl in the management of acute pain due to oral mucositis in patients receiving stem cell transplantation."3.73Effectiveness of transdermal fentanyl patch for treatment of acute pain due to oral mucositis in patients receiving stem cell transplantation. ( Bae, NY; Baek, JH; Chae, YS; Kim, DH; Kim, JG; Kim, SY; Lee, KB; Sohn, SK, 2005)
"There is a trend to use fentanyl patch as first-choice strong opioid in cancer patients in situations such as titration phase, in the presence of instable pain, and in the absence of dysphagia or gastrointestinal symptoms where the use of oral morphine is, however, not contraindicated."3.73Is the use of transdermal fentanyl inappropriate according to the WHO guidelines and the EAPC recommendations? A study of cancer patients in Italy. ( Brunelli, C; Campa, T; De Conno, F; Fagnoni, E; Ripamonti, C, 2006)
"The use of fentanyl patches has become accepted as standard in Germany for the treatment of chronic and cancer pain."3.73[Medico-legal aspects of the use of fentanyl patches]. ( Zimmermann, M, 2006)
" Data from patients with noncancer or cancer pain treated with TD buprenorphine or TD fentanyl for at least 3 months between May 2002 and April 2005 were analyzed."3.73Patterns of dosage changes with transdermal buprenorphine and transdermal fentanyl for the treatment of noncancer and cancer pain: a retrospective data analysis in Germany. ( Nuijten, M; Poulsen Nautrup, B; Sittl, R, 2006)
"The present study was undertaken to investigate the possible change in anti-hyperalgesic effect following repeated treatment with morphine or fentanyl using the dose to improve the thermal hyperalgesia under an inflammatory pain-like state."3.73Differences in tolerance to anti-hyperalgesic effects between chronic treatment with morphine and fentanyl under a state of pain. ( Hareyama, N; Hashimoto, S; Imai, S; Miyoshi, K; Nakamura, A; Narita, M; Nozaki, H; Suzuki, M; Suzuki, T; Takagi, T, 2006)
"Despite ketoprofen infusion and free access to a patient-controlled pump with fentanyl citrate for rescue analgesia, inadequate pain relief was common both after uvulopalatoplasty (35%) and after tonsillectomy (28%) during the first 24 hours after surgery."3.72Pain intensity after laseruvulopalatoplasty and tonsillectomy. ( Aho, M; Kokki, H; Nikanne, E; Virtaniemi, J, 2003)
"The delayed effects (12-16 hours) of transdermal fentanyl make dose titration difficult during acute exacerbations of cancer pain."3.72A safe and effective method for converting patients from transdermal to intravenous fentanyl for the treatment of acute cancer-related pain. ( Kornick, CA; Manfredi, PL; O'Brien, PC; Payne, R; Santiago-Palma, J; Schulman, G; Weigand, S, 2003)
"Although fentanyl has been reported to cause CNS excitation in horses, a transdermal therapeutic system (TTS) containing this mu agonist has recently been used empirically in equine medicine to treat moderate to severe pain."3.72Pharmacokinetics of fentanyl following intravenous and transdermal administration in horses. ( Kollias-Baker, C; Maxwell, LK; Slovis, N; Thomasy, SM, 2003)
"Partial opioid substitution with fentanyl and moderate levels of hydration had no significant preventive effects on the occurrence of agitated delirium in the last week on a mass level."3.72Agitated terminal delirium and association with partial opioid substitution and hydration. ( Inoue, S; Morita, T; Tei, Y, 2003)
"A Markov model was constructed to simulate the resource use and health outcomes of one year of treatment comparing the fentanyl transdermal therapeutic system (fentanyl-TTS) with oral sustained-release (SR) morphine in outpatients with noncancer pain in Denmark."3.72A one year health economic model comparing transdermal fentanyl with sustained-release morphine in the treatment of chronic noncancer pain. ( Andersen, S; Frei, A; Hole, P; Jensen, NH, 2003)
"A retrospective cohort design study was conducted to determine the incidence of constipation in chronic pain patients who received three different long-acting opioids (transdermal fentanyl, oxycodone HCl controlled-release [CR], or morphine CR) for malignant or nonmalignant chronic pain."3.72Incidence of constipation associated with long-acting opioid therapy: a comparative study. ( Markowitz, J; Schein, J; Staats, PS, 2004)
"To evaluate driving performance, cognition, and balance in patients with chronic nonmalignant pain before and after the addition of transdermal fentanyl to their treatments."3.72The effects of transdermal fentanyl on driving, cognitive performance, and balance in patients with chronic nonmalignant pain conditions. ( Besser, M; Crerand, C; Frank, ED; Jalali, S; Menefee, LA; Park, J; Sanschagrin, K, 2004)
"The authors previously reported changes in electroencephalographic bicoherence during isoflurane anesthesia combined with epidural anesthesia."3.72Electroencephalographic bicoherence is sensitive to noxious stimuli during isoflurane or sevoflurane anesthesia. ( Hagihira, S; Mashimo, T; Mori, T; Takashina, M; Ueyama, H, 2004)
"To assess the analgesic safety and efficacy of Transdermal Therapeutic System (TTS)-fentanyl in the treatment of chronic gynecological cancer-related pain."3.72Evaluation of safety and efficacy of transdermal therapeutic system-fentanyl in adult patients with gynecological cancer-related pain. ( Cheewakriangkrai, C; Katanyoo, K; Lorvidhaya, V; Srisomboon, J; Suprapaphorn, P, 2004)
"Transdermal fentanyl is an opioid analgesic that is effective on chronic pain, and which appears to be advantageous due to several factors such as ease of administration, the relatively stable serum concentration and long dose intervals."3.72Oral transmucosal abuse of transdermal fentanyl. ( Dimopoulos, NP; Gitsa, OE; Liappas, AI; Liappas, IA; Mellos, E; Rabavilas, AD, 2004)
"(1) Some cancer patients suffer occasional breakthrough pain despite well-conducted opiate treatment, warranting the use of immediate-release oral morphine."3.71Oral transmucosal fentanyl: new preparation. For breakthrough cancer pain when morphine fails. ( , 2002)
"The role of the supraspinal endogenous opioid system in pain processing has been investigated in this study using positron emission tomography imaging of [11C]-carfentanil, a synthetic, highly specific mu opioid receptor (mu-OR) agonist."3.71Pain activation of human supraspinal opioid pathways as demonstrated by [11C]-carfentanil and positron emission tomography (PET). ( Bencherif, B; Campbell, JN; Dannals, RF; Frost, JJ; Fuchs, PN; Sheth, R, 2002)
"Early and significant reduction in pain (compared to baseline assessments) was achieved in children using intranasal fentanyl by 10 min and sustained throughout the 30 min of observations."3.71Intranasal fentanyl reduces acute pain in children in the emergency department: a safety and efficacy study. ( Borland, ML; Geelhoed, G; Jacobs, I, 2002)
"This open compassionate-use prospective registration study evaluated the tolerability, ease of use and applied doses of transdermal (TTS) fentanyl in adult patients with cancer-related pain requiring strong opioid analgesia."3.71Longitudinal follow-up of TTS-fentanyl use in patients with cancer-related pain: results of a compassionate-use study with special focus on elderly patients. ( Desmedt, M; Lossignol, D; Menten, J; Mullie, A, 2002)
"This prospective, open-label, before-after trial was designed to compare the efficacy of oral opioids with that of transdermal fentanyl in severe AIDS-related chronic pain, as well as assess barriers, patient satisfaction, and side effects."3.71Transdermal fentanyl for chronic pain in AIDS: a pilot study. ( Lefkowitz, M; Newshan, G, 2001)
"The fentanyl transdermal system (Duragesic) is an opioid analgesic indicated for the management of chronic moderate to severe pain."3.71Economic evaluation of the fentanyl transdermal system for the treatment of chronic moderate to severe pain. ( Bell, TJ; Dodd, SL; Neighbors, DM; Wilson, J, 2001)
"An expert working group of the European Association for Palliative Care has revised and updated its guidelines on the use of morphine in the management of cancer pain."3.71Morphine and alternative opioids in cancer pain: the EAPC recommendations. ( Casas, JR; Cherny, N; Conno, F; Hanks, GW; Hanna, M; Kalso, E; McQuay, HJ; Mercadante, S; Meynadier, J; Poulain, P; Radbruch, L; Ripamonti, C; Sawe, J; Twycross, RG; Ventafridda, V, 2001)
"The study examined the validity of oral fentanyl self-administration (FSA) as a measure of the chronic nociceptive pain that develops in rats with adjuvant arthritis independently of acute noxious challenges."3.71Opiate self-administration as a measure of chronic nociceptive pain in arthritic rats. ( Alliaga, M; Attal, N; Bruins Slot, LA; Colpaert, FC; Koek, W; Tarayre, JP, 2001)
"This multicentre, observational study examined the efficacy of the therapeutic transdermal fentanyl system (TTS-fentanyl) in children requiring opioids for pain in life-threatening disease."3.71Transdermal fentanyl for pain relief in a paediatric palliative care population. ( Devine, T; Goldman, A; Hunt, A; Phillips, M, 2001)
"Oral morphine is the treatment first recommended for nociceptive pain insufficiently relieved by WHO level I and II analgesics."3.71[New Level III opioids of the World Health Organization]. ( Laval, G; Mallaret, M; Sang, B; Villard, ML, 2002)
"We describe two cases of unexpected perineal pain immediately after intravenous injection of fentanyl and dexamethasone (100 microg and 8 mg respectively) during induction of general anaesthesia."3.71Excruciating perineal pain after intravenous dexamethasone. ( Neff, SP; Stapelberg, F; Warmington, A, 2002)
"Continuous fentanyl infusion should be considered for the treatment of cancer pain in patients requiring high doses who become refractory to other opioids, when other opioids cause intolerable adverse effects, when patients have a true morphine allergy, or when high-dose requirements threaten to deplete existing stock of alternate opioids."3.70Continuous fentanyl infusion: use in severe cancer pain. ( Dunlap, DS; Lenz, KL, 1998)
"A transdermal fentanyl patch for the treatment of chronic cancer-related pain is available in four dosages (25, 50, 75, and 100 microg/hr)."3.70Factors influencing quality of life in cancer patients: the role of transdermal fentanyl in the management of pain. ( Payne, R, 1998)
" Our aim was to determine whether a novel breath-actuated, microprocessor-controlled metered dose oral inhaler (SmartMist, Aradigm Corporation) could deliver fentanyl in a way suitable for control of severe pain."3.70Pulmonary administration of aerosolised fentanyl: pharmacokinetic analysis of systemic delivery. ( Eltherington, LG; Farr, SJ; Mather, LE; Rubsamen, RA; Ward, ME; Woodhouse, A, 1998)
"This study confirms that the addition of lumbar epidural fentanyl 100 micrograms to 15 mg of epidural bupivacaine provides good control of labour pain with no motor block and establishes that this combination preserves dorsal column sensory function."3.70Intact proprioception and control of labour pain during epidural analgesia. ( Abrahams, M; Breen, P; Gardiner, J; Higgins, P; Muttu, S; Whyte, P, 1999)
"In this experimental pain model, activation of peripheral mu or kappa opioid receptors can attenuate capsaicin-induced thermal hyperalgesia in rats."3.70Local administration of mu or kappa opioid agonists attenuates capsaicin-induced thermal hyperalgesia via peripheral opioid receptors in rats. ( Johnson, MD; Ko, MC; Tuchman, JE; Wiesenauer, K; Woods, JH, 2000)
"To evaluate the proportion of drug abuse related to opioid analgesics and the trends in medical use and abuse of 5 opioid analgesics used to treat severe pain: fentanyl, hydromorphone, meperidine, morphine, and oxycodone."3.70Trends in medical use and abuse of opioid analgesics. ( Dahl, JL; Gilson, AM; Joranson, DE; Ryan, KM, 2000)
" The current report details five children in whom a percutaneously placed lumbar intrathecal catheter was used: (i) to provide intraoperative surgical anaesthesia instead of general anaesthesia (ii); to deliver intrathecal fentanyl to provide postoperative analgesia (iii); to provide chronic pain control during the terminal stages of metastatic malignancy; (iv) to allow repeated doses of intrathecal chemotherapy; and (v) to allow CSF drainage and prevent CSF leakage following frontal encephalocele repair."3.70Applications of intrathecal catheters in children. ( Tobias, JD, 2000)
"The transdermal fentanyl patch is proving to be a safe, well tolerated and effective treatment modality in the control of cancer pain, but care has to be exercised when using this drug, especially at the time of initiation, as the consequences may be disastrous for the patient."3.70A pitfall to avoid when starting a patient on transdermal fentanyl. ( Chye, R; Low, JA, 2000)
"Epidural analgesia with local anesthetics administered alone or in combination with fentanyl effectively and safely treats the pain of sickle cell vaso-occlusive crisis unresponsive to conventional pain management and does so without causing sedation, respiratory depression, or significant limitation on ambulation."3.69Epidural analgesia in the management of severe vaso-occlusive sickle cell crisis. ( Billett, C; Casella, JF; Dover, G; Tobin, JR; Yaster, M, 1994)
" with formalin, behavioural correlates of the amount and pattern of Fos-like immunoreactivity (Fos-Ll) (molecular responses to pain) were studied to test if early phase treatment with 75% nitrous oxide or 2% halothane, or both, suppressed subsequent spinal sensitization."3.69Nitrous oxide or halothane, or both, fail to suppress c-fos expression in rat spinal cord dorsal horn neurones after subcutaneous formalin. ( Shieh, JY; Shyu, BC; Sun, WZ, 1996)
"Over an eight-month period, a convenience sample of consenting patients at an urban teaching hospital ED who required sedation for painful procedures were enrolled in a descriptive study of therapeutic propofol sedation."3.69The use of propofol for sedation in the emergency department. ( Mathias, S; Seaberg, DC; Swanson, ER, 1996)
"To study use of Duragesic (fentanyl transdermal system), the only transdermal opioid approved in Canada for treating chronic cancer pain in adults."3.69Fentanyl transdermal system. Pain management at home. ( Hays, H; Woodroffe, MA, 1997)
" administration of acetic acid produces abdominal contractions reflecting visceral pain, and gastrointestinal ileus characterized by inhibition of gastric emptying and small intestine transit."3.69Reversal by kappa-agonists of peritoneal irritation-induced ileus and visceral pain in rats. ( Angel, F; Chevalier, E; Dahl, SG; Friese, N; Junien, JL; Pascaud, X; Riviere, PJ, 1997)
"A 62-year-old man receiving subcutaneous fentanyl for the management of cancer pain developed generalized central excitation after an overdose of 5000 micrograms of fentanyl."3.69Acute neuropsychiatric findings in a patient receiving fentanyl for cancer pain. ( Bruera, E; Pereira, J, 1997)
"In a 32 years old patient with advanced gastric cancer epidural analgesia with local anaesthetic and morphine via a thoracic epidural catheter was required because of intractable pain and intolerable side effects of intravenous morphine."3.69[Conversion from peridural to transdermal opiate analgesia in abdominal tumor pain syndrome]. ( Fösel, T; Gaiser, H; Müller, R; Schuler, M, 1997)
"To report a case of high transdermal fentanyl dosage requirements in a patient with chronic cancer pain."3.68High transdermal fentanyl requirements in a patient with chronic cancer pain. ( Lehr, VT; Renaud, EA, 1993)
"These results suggest that steady-state serum concentrations are approached by the second dose of TTS(fentanyl) and that the kinetics are stable with repeated dosing."3.68Transdermal fentanyl for cancer pain. Repeated dose pharmacokinetics. ( Foley, KM; Gupta, SK; Inturrisi, CE; Lapin, J; Layman, M; Portenoy, RK; Southam, MA, 1993)
" A retrospective analysis of 79 ESWL procedures on 73 consecutive unselected patients was done in an attempt to determine the effectiveness of TENS in reducing the amount of intravenous fentanyl citrate and/or midazolam HCl needed to control pain and anxiety during the ESWL procedure."3.68The use of transcutaneous electrical nerve stimulation during the biliary lithotripsy procedure. ( Baumgartner, BR; Evans, GR; Fraser, NP; Jones, V; Nelson, RC; Peterson, J; Torres, WE, 1992)
"The author studied the use of intravenous Propofol for the relief of pain."3.68[Changes in the pain produced by the peripheral venous injection of propofol when it is combined with lidocaine or fentanyl]. ( Croston, J; de Henriquez, L; de Jiménez, L; Espinosa, V, 1992)
"Five children with cancer pain were given continuous intrathecal morphine or fentanyl infusion associated with bupivacaine 0."3.68[Intrathecal morphine therapy in children with cancer]. ( Ganansia, MF; Lejus, C; Meignier, M; Testa, S, 1992)
"Diagnostic epidural blocks were performed on 27 chronic pain patients sequentially using saline, fentanyl, and lidocaine solution."3.67Diagnostic epidural opioid technique. ( Ellis, JS; Hoffman, J; Ramamurthy, S; Schoenfeld, LS; Walsh, NE, 1989)
"Perineal pain during the course of routine epidural analgesia with bupivacaine was treated with a 10-ml top-up of either bupivacaine 25 mg, fentanyl 100 micrograms or fentanyl 100 micrograms plus bupivacaine 10 mg, in 46 women in the first stage of labour."3.67Epidural fentanyl and perineal pain in labour. ( O'Sullivan, G; Reynolds, F, 1989)
"Five cancer patients experienced satisfactory pain relief for periods of 3-156 days using continuous transdermal delivery of the narcotic fentanyl."3.67Transdermal fentanyl for pain control in patients with cancer. ( Dothage, JA; Miser, AW; Miser, JS; Narang, PK; Sindelar, W; Young, RC, 1989)
"To investigate the selective role of intraspinal opioids on the perception and modulation of pain, seven subjects with chronic hip or back pain and one subject with C-6 quadriplegia received 25 micrograms of intrathecal fentanyl."3.67Intrathecal fentanyl depresses nociceptive flexion reflexes in patients with chronic pain. ( Chabal, C; Jacobson, L; Little, J, 1989)
"1 micrograms/kg fentanyl in low back pain patients reduced both sensory intensity and unpleasantness visual analogue scale (VAS) responses to experimental pain evoked by graded 5-sec nociceptive temperature stimuli (45-51 degrees C) as well as VAS-sensory and VAS-affective responses to clinical pain."3.67A simultaneous comparison of fentanyl's analgesic effects on experimental and clinical pain. ( Harkins, SW; Price, C; Price, DD; Rafii, A, 1986)
"The effect of thyrotropin releasing hormone (TRH) on modified neuroleptanesthesia with fentanyl-flunitrazepam was investigated in an open pilot study of 15 neurosurgical patients."3.67Failure of thyrotropin releasing hormone to reverse fentanyl-flunitrazepam anesthesia in man. ( Dangelmaier, R; Glöser, A; Hempel, V; Lenz, G, 1986)
"The effects of a continuous epidural administration of fentanyl on pain and on ventilation were studied in eight patients scheduled for orthopedic surgery of the knee."3.67Ventilatory effects of continuous epidural infusion of fentanyl. ( Brichant, JF; Chauvin, M; Clergue, F; Levron, JC; Renaud, B; Viars, P, 1988)
" This work was performed in order to evaluate the dose-response relationship, time course, and naloxone reversibility of fentanyl suppression of neurons that are involved with the transmission of information about pain."3.66Dose-response suppression of noxiously evoked activity of WDR neurons by spinally administered fentanyl. ( Collins, JG; Kitahata, LM; Matsumoto, M; Suzukawa, M; Yuge, O, 1983)
" For unanesthetized tubes the mean pain rating depended on the dose of diazepam and fentanyl given to the patient (p less than ."3.65Laparoscopic tubal clip sterilization under local anesthesia. ( Edelman, DA; Fishburne, JI; Hulka, JF; Mercer, JP; Omran, KF, 1974)
"Hemorrhage is a leading cause of preventable battlefield and civilian trauma deaths."3.30Comparing the Effects of Low-Dose Ketamine, Fentanyl, and Morphine on Hemorrhagic Tolerance and Analgesia in Humans. ( Belval, LN; Cramer, MN; Crandall, CG; Foster, J; Hendrix, JM; Hinojosa-Laborde, C; Huang, M; Moralez, G; Watso, JC, 2023)
"The pre-treatment pain severity of the groups was similar (p = 0."3.30The efficacy of intradermal sterile water application in severe renal colic: a randomised clinical trial. ( Ak, R; Aykanat, MC; Cimilli Öztürk, T; Kılıç, M; Ustaalioğlu, İ, 2023)
"Fentanyl was the opioid used in the OCA group."3.11A comparison of opioid-containing anesthesia versus opioid-free anesthesia using the Cortínez-Sepúlveda model on differential cytokine responses in obese patients undergoing gastric bypass surgery: a randomized controlled trial. ( Campos-Pérez, W; Cuevas, JHM; González-Landeros, D; Martínez-López, E; Pérez-Robles, M; Pérez-Vargas, L; Ramírez-Plascencia, L; Rivera-Valdés, JJ; Sánchez-Muñoz, P, 2022)
"Patients with renal lithiasis were included and were randomized to Group A (basal analgesia: midazolam (1 mg), fentanyl (0."3.11Value of Music and Nitrous Oxide for Pain Control during Extracorporeal Shock Wave Lithotripsy (ESWL). ( Alcoba-García, MP; Bueno-Serrano, G; González-Enguita, C; González-López, R; Llanos-Jiménez, L; Mahillo-Fernández, I; Tabares-Jiménez, J, 2022)
" The efficacy and safety of the sedations including sedation time intervals, nausea score, vomiting episodes, pain score, adverse effects, and parent's satisfaction were evaluated."3.11The efficacy and safety of midazolam with fentanyl versus midazolam with ketamine for bedside invasive procedural sedation in pediatric oncology patients: A randomized, double-blinded, crossover trial. ( Lertvivatpong, N; Malaithong, W; Monsereenusorn, C; Photia, A; Rujkijyanont, P; Traivaree, C, 2022)
"Using Department of Defense Trauma Registry data for the Afghanistan conflict from 2005 to 2018, we examined 2,402 records of prehospital analgesia administration to assess temporal trends in medication choice and proportions receiving analgesia, including subanalysis of a cohort screened for an indication with minimal contraindication for analgesia."3.01Patterns of Palliation: A Review of Casualties That Received Pain Management Before Reaching Role 2 in Afghanistan. ( Burgess, M; Hinojosa-Laborde, C; Hudson, IL; Newberry, RK; Ryan, KL; Schauer, SG; Staudt, AM; VanFosson, CA, 2023)
"Remifentanil PCA was superior to fentanyl PCA for analgesia at an early time point, and it increased the incidence of oxygen desaturation relative to other strategies of delivering epidural solution."3.01Comparison of different delivery modalities of epidural analgesia and intravenous analgesia in labour: a systematic review and network meta-analysis. ( Desai, N; Nzekwu, B; Onwochei, D; Owolabi, A; Wydall, S; Zolger, D, 2023)
"Fentanyl was not associated with mortality risk compared to the control (risk ratio: 0."3.01Effect of Fentanyl for Preterm Infants on Mechanical Ventilation: A Systematic Review and Meta-Analysis. ( Haga, M; Kajikawa, D; Kuratsuji, G; Namba, F; Ota, E; Seki-Nagasawa, J; Shokraneh, F; Sudo, Y; Yamaji, N, 2023)
"Propofol is a commonly used sedative, frequently combined with an opioid or low-dose ketamine as an analgesic."3.01Low-dose ketamine or opioids combined with propofol for procedural sedation in the emergency department: a systematic review. ( De Vries, LJ; Lameijer, H; Van Roon, EN; Veeger, NJGM, 2023)
"An observer masked to the treatment assessed pain, pre- and postoperatively, with the Glasgow (GCPS), the Colorado (CPS) pain scales and a Visual Analogue Scale (VAS); additionally, the mechanical thresholds (MT) were measured with the Electronic von Frey Anaesthesiometer (EVF) at four points located near the herniated disc."2.94Use of acupuncture as adjuvant analgesic technique in dogs undergoing thoracolumbar hemilaminectomy. ( Adami, C; Machin, H; Taylor-Brown, F, 2020)
" (4) Compared with control group with the same sedative, the duration of mechanical ventilation, extubation time, length of ICU stay were significantly shortened, and the dosage of sedative drugs used was reduced in study group (all P < 0."2.82[Study of prevention and control of delirium in ventilated patients by simulating blockage of circadian rhythm with sedative in intensive care unit]. ( Dong, C; Feng, F; Li, J; Qi, Y; Song, R; Yang, J; Yang, Z; Zhang, H, 2016)
"And propofol was used for rescue."2.79[Sedative effects of dexmedetomidine in post-operative elder patients on mechanical ventilation]. ( Huang, F; Jin, J; Kong, J; Liu, S; Wang, J; Xu, H; Yang, X, 2014)
"2201 cancer pain patients were included."2.77Lack of association between genetic variability and multiple pain-related outcomes in a large cohort of patients with advanced cancer: the European Pharmacogenetic Opioid Study (EPOS). ( Fayers, P; Fladvad, T; Kaasa, S; Klepstad, P; Skorpen, F, 2012)
" There was no significant difference in the incidence of adverse effects between the two drugs."2.77The effectiveness and adverse events of morphine versus fentanyl on a physician-staffed helicopter. ( Cudnik, M; Emerman, CL; Pakiela, J; Smith, DA; Smith, MD; Wang, Y, 2012)
"Severe pain is defined as rated seven or greater on a 0 to 10 age-appropriate numeric pain scale or equivalent."2.77Intranasal fentanyl versus intravenous morphine in the emergency department treatment of severe painful sickle cell crises in children: study protocol for a randomised controlled trial. ( an Fhailí, S; Barrett, MJ; Cronin, J; Grant, T; Hayden, J; McCoy, S; McMahon, C; Murphy, A; O'Sullivan, R; Wakai, A; Walsh, S, 2012)
" We aimed to determine the analgesic and adverse effects of intrathecal neostigmine combined with hyperbaric bupivacaine and fentanyl."2.77Analgesic effect of intrathecal neostigmine combined with bupivacaine and fentanyl. ( Akinwale, MO; Akinyemi, OA; Sotunmbi, PT, 2012)
"Patients with chronic cancer pain were randomly assigned to the conversion from continuous intravenous infusion to transdermal fentanyl using two-step taper of the continuous intravenous infusion in 12 h (12-h method) or the conversion in 6 h (6-h method)."2.76Six- versus 12-h conversion method from intravenous to transdermal fentanyl in chronic cancer pain: a randomized study. ( Hayashi, K; Kamata, M; Kojima, H; Kozai, M; Nomura, M; Sawada, S, 2011)
"Of 139 recruited patients, 69% identified an effective dose of sublingual fentanyl ODT (a dosage that successfully treated all episodes of BTcP over two consecutive days) and entered the maintenance phase, during which they were treated for a median of 149."2.76Long-term effectiveness and tolerability of sublingual fentanyl orally disintegrating tablet for the treatment of breakthrough cancer pain. ( Derrick, R; Dumble, S; Hassman, D; Howell, J; Nalamachu, S; Wallace, MS, 2011)
" Adverse events were also recorded."2.76The efficacy and safety of fentanyl buccal tablet compared with immediate-release oxycodone for the management of breakthrough pain in opioid-tolerant patients with chronic pain. ( Ashburn, MA; Messina, J; Slevin, KA; Xie, F, 2011)
" Adverse events were recorded throughout."2.76Sublingual fentanyl orally disintegrating tablet in daily practice: efficacy, safety and tolerability in patients with breakthrough cancer pain. ( Müller-Schwefe, GH; Überall, MA, 2011)
"Endovascular abdominal aortic aneurysm (AAA) repair was performed with local anaesthesia and intravenous analgesia."2.76Analgesia and endocrine surgical stress: effect of two analgesia protocols on cortisol and prolactin levels during abdominal aortic aneurysm endovascular repair. ( Baraldi, E; Barbieri, A; Coppi, G; D'Amico, R; Ferrari, A; Genazzani, A; Giuliani, E, 2011)
"Modafinil 200 mg was administered to the treatment group patients 1 h before sedation/analgesia."2.75Modafinil reduces patient-reported tiredness after sedation/analgesia but does not improve patient psychomotor skills. ( Boesjes, H; Galvin, E; Hol, J; Klein, J; Ubben, JF; Verbrugge, SJ, 2010)
"Open-label, randomized, four-period, Latin-square crossover pharmacokinetic study."2.75Single-dose pharmacokinetics of fentanyl buccal soluble film. ( Finn, AL; Gever, LN; Tagarro, I; Vasisht, N, 2010)
"During maintenance treatment, 70 of 646 patients (11%) discontinued because of adverse events (AEs), 69 of 646 (11%) because of withdrawn consent, and 57 of 646 (9%) because of noncompliance."2.75Long-term safety and tolerability of fentanyl buccal tablet for the treatment of breakthrough pain in opioid-tolerant patients with chronic pain: an 18-month study. ( Fine, PG; Messina, J; Rathmell, J; Xie, F, 2010)
" The dosage used was 50% of that indicated in equipotency conversion tables."2.74Opioids switching with transdermal systems in chronic cancer pain. ( Aurilio, C; Barbarisi, M; Grella, E; Pace, MC; Passavanti, MB; Pota, V; Sansone, P, 2009)
"Fentanyl is an opioid with high lipid solubility, suitable for intravenous, spinal, transmucosal and transdermal administration."2.74Transdermal fentanyl in cachectic cancer patients. ( Gergov, M; Haakana, S; Heiskanen, T; Kalso, E; Mätzke, S; Vuori, E, 2009)
"Breakthrough cancer pain (BTcP) represents an important clinical challenge in the care of patients with cancer."2.74Efficacy and long-term tolerability of sublingual fentanyl orally disintegrating tablet in the treatment of breakthrough cancer pain. ( Bartkowiak, AJ; Derrick, R; Hassman, D; Hayes, TG; Howell, J; Nalamachu, S; Rauck, RL; Reyes, E; Tark, M, 2009)
" Any adverse events were recorded; four tolerability endpoints, constipation, nausea, daytime drowsiness, and sleeping disturbances, were assessed daily."2.73A randomized, open, parallel group, multicenter trial to investigate analgesic efficacy and safety of a new transdermal fentanyl patch compared to standard opioid treatment in cancer pain. ( Heiskanen, T; Hoerauf, KH; Jensen, NH; Krenn, H; Kress, HG; Lundorff, L; Nolte, T; Petersen, R; Rosland, JH; Sabatowski, R; Saedder, EA; Von der Laage, D, 2008)
"To determine whether healthy and traumatized dogs receiving a constant rate infusion (CRI) of either morphine or fentanyl have decreased urine production."2.73Effects of morphine and fentanyl constant rate infusion on urine output in healthy and traumatized dogs. ( Anderson, MK; Day, TK, 2008)
"2% of patients experienced adverse events that were either probably related or very likely to be related to the study drug."2.73Safety and efficacy of transdermal fentanyl in patients with cancer pain: phase IV, Turkish oncology group trial. ( Aliustaoğlu, M; Altinbaş, M; Altundağ, K; Atahan, L; Cooper, R; Demirkan, B; Kömürcü, S; Manavoğlu, O; Ozdemir, F; Ozkök, S; Pak, Y; Sarihan, S; Turhal, S; Turna, HS; Yavuz, AA; Yaylaci, M, 2007)
"In episodes treated with IV-MO, pain intensity decreased from a mean of 6."2.73Transmucosal fentanyl vs intravenous morphine in doses proportional to basal opioid regimen for episodic-breakthrough pain. ( Casuccio, A; Ferrera, P; Intravaia, G; Mangione, S; Mercadante, S; Villari, P, 2007)
" Pain intensity (PI) (rated on an 11-point pain scale, from 0 = no pain to 10 = worst pain) and other outcomes were assessed before dosing and for 2 hours after dosing."2.73Fentanyl buccal tablet for the relief of breakthrough pain in opioid-tolerant adult patients with chronic neuropathic pain: a multicenter, randomized, double-blind, placebo-controlled study. ( Hale, M; Messina, J; Simpson, DM; Xie, F, 2007)
"Remifentanil prevented increase in MAP and HR while alfentanil and fentanyl were ineffective in this purpose (p < 0."2.73Analgesia for retrobulbar block--comparison of remifentanil, alfentanil and fentanyl. ( Asadipour, E; Maghsoudi, B; Talebnejad, MR, 2007)
"Although common treatments for osteoarthritis (OA) pain, such as nonsteroidal antiinflammatory drugs (NSAIDs), simple analgesics, and weak opioids, provide relief in some cases, they fail to control pain or are poorly tolerated in many cases."2.72Transdermal fentanyl for improvement of pain and functioning in osteoarthritis: a randomized, placebo-controlled trial. ( Langford, R; McKenna, F; Ratcliffe, S; Richarz, U; Vojtassák, J, 2006)
"Buprenorphine causes limited respiratory depression with a ceiling effect at higher doses, while fentanyl causes dose-dependent respiratory depression with apnoea at high dose levels."2.72Opioid-induced respiratory effects: new data on buprenorphine. ( Dahan, A, 2006)
"The primary objective of this study was to compare the relative bioavailability of FEBT 1,080 microg with that of oral transmucosal fentanyl citrate (OTFC) 1,600 microg, and the secondary objective was to assess the dose proportionality of FEBT 270 to 1,300 microg in healthy adult volunteers."2.72Relative bioavailability of the fentanyl effervescent buccal tablet (FEBT) 1,080 pg versus oral transmucosal fentanyl citrate 1,600 pg and dose proportionality of FEBT 270 to 1,300 microg: a single-dose, randomized, open-label, three-period study in healt ( Darwish, M; Kirby, M; Tempero, K; Thompson, J, 2006)
" The magnitude of analgesia in the cold pressor model showed some correlation with TDF dosage and comparable effects for the full agonist fentanyl and the partial agonist buprenorphine."2.72Differential sensitivity of three experimental pain models in detecting the analgesic effects of transdermal fentanyl and buprenorphine. ( Gasser, UE; Koltzenburg, M; Pokorny, R; Richarz, U, 2006)
" The objective of this study was to further evaluate the pharmacokinetic effect of local heat administration on fentanyl drug delivery through the transdermal fentanyl patch delivery system in volunteers."2.71The pharmacokinetics of transdermal fentanyl delivered with and without controlled heat. ( Ashburn, MA; Basta, SV; Love, G; Ogden, LL; Zhang, J, 2003)
"Patients receiving propofol reached full recovery sooner (16."2.71Propofol versus midazolam/fentanyl for outpatient colonoscopy: administration by nurses supervised by endoscopists. ( Chadalawada, V; Hansen, JJ; Liangpunsakul, S; Mendel, AM; Overley, CA; Rex, DK; Strahl, E; Symms, MR; Ulmer, BJ, 2003)
"Fentanyl is a synthetic opioid that can be delivered through a transdermal therapeutic system (TTS)."2.71Transdermal fentanyl in HSCT patients: an open trial using transdermal fentanyl for the treatment of oral mucositis pain. ( Carrassi, A; Deliliers, GL; Demarosi, F; Lodi, G; Sardella, A; Soligo, D; Volpe, AD, 2004)
" Fourteen patients receiving strong opioids who had increased their dosage more than 100% in the last week unsuccessfully were randomly chosen to add a second opioid to the first using an initial equivalent dosage of 20% of the previous therapy."2.71Addition of a second opioid may improve opioid response in cancer pain: preliminary data. ( Casuccio, A; Ferrera, P; Mercadante, S; Villari, P, 2004)
"Remifentanil is a short acting, potent synthetic opioid that does not accumulate after infusion or repeated bolus doses."2.71Remifentanil vs fentanyl/morphine for pain and stress control during pediatric cardiac surgery. ( Arana, A; Bell, G; Dickson, U; Marshall, C; Morton, N; Robinson, D, 2004)
" In this respect, further studies related to dosage of intrathecal levobupivacaine in obstetric labor analgesia will be beneficial in substantiating this point."2.71Intrathecal labor analgesia using levobupivacaine 2.5 mg with fentanyl 25 microg--would half the dose suffice? ( Chan, SY; Chiu, JW, 2004)
" Pharmacokinetic parameters were calculated by noncompartment analysis."2.71Pharmacokinetics and tolerability of different doses of fentanyl following sublingual administration of a rapidly dissolving tablet to cancer patients: a new approach to treatment of incident pain. ( Bredenberg, S; Hedner, T; Holmberg, M; Lennernäs, B; Lennernäs, H; Nyström, C, 2005)
"Pain was assessed using a 10-point verbal analogue scale and <3 was considered adequate analgesia."2.71Target-controlled infusion of remifentanil or fentanyl during extra-corporeal shock-wave lithotripsy. ( Acuña, D; Cortínez, LI; Dagnino, JA; De la Fuente, R; Muñoz, HR, 2005)
"If fentanyl was given with the lidocaine in the para-cervical block, it potentially could improve pain control while decreasing side effects and avoiding i."2.71Intra-cervical versus i.v. fentanyl for abortion. ( Savoy, E; Trouton, KJ; Wiebe, ER, 2005)
" In groups 6 and 7, additional fentanyl doses were lower than in the other groups, but only in group 7 was the total fentanyl dosage low."2.71Effectiveness of eutectic mixture of local anesthetic cream and occlusive dressing with low dosage of fentanyl for pain control during shockwave lithotripsy. ( Basar, H; Basar, MM; Batislam, E; Ozcan, S; Tuglu, D; Yilmaz, E, 2005)
" Large patient-to-patient variations in pharmacokinetic parameters occurred, although intraindividual variability was limited."2.71Inter- and intraindividual variabilities in pharmacokinetics of fentanyl after repeated 72-hour transdermal applications in cancer pain patients. ( Bressolle, F; Caumette, L; Culine, S; Garcia, F; Pinguet, F; Poujol, S; Solassol, I, 2005)
" In the 16 who received fentanyl for > or =3 months until death, the median dose was unchanged (100 microg/h) 3 months before death and at death; 8/16 required no dosage change."2.70Long-term observations of patients receiving transdermal fentanyl after a randomized trial. ( Ahmedzai, SH; Brooks, D; Davis, C; Nugent, M, 2001)
"We used infantile neuronal ceroid lipofuscinosis (INCL), in which deterioration of the central nervous system is extremely rapid, to study constant release of an opioid for pains of central origin in a metabolic disease."2.70Transdermal fentanyl therapy for pains in children with infantile neuronal ceroid lipofuscinosis. ( Heiskala, HJ; Mannerkoski, MK; Pouttu, JA; Santavuori, PR, 2001)
"The treatment of cancer pain with transdermal fentanyl can be performed as a long-term therapy and result in good pain relief."2.69Long-term treatment of cancer pain with transdermal fentanyl. ( Donner, B; Raber, M; Strumpf, M; Zenz, M, 1998)
"TTS fentanyl was titrated to pain relief, and patients were followed up for as long as 3 months."2.69A clinical evaluation of transdermal therapeutic system fentanyl for the treatment of cancer pain. ( Hays, H; Moulin, DE; Sloan, PA, 1998)
"To treat cancer pain, physicians often decide to jump directly from step 1 of the World Health Organization (WHO) analgesic ladder to step 3."2.69Transdermal fentanyl in opioid-naive cancer pain patients: an open trial using transdermal fentanyl for the treatment of chronic cancer pain in opioid-naive patients and a group using codeine. ( Mattern, C; Uitendaal, MP; Vielvoye-Kerkmeer, AP, 2000)
"Fentanyl has no effect on the perceived intensity or unpleasantness of vibratory stimulation, which continues to activate contralateral S1."2.69Selective opiate modulation of nociceptive processing in the human brain. ( Casey, KL; Jone, C; Minoshima, S; Morrow, TJ; Raz, J; Svensson, P, 2000)
"Morphine was started i."2.69Comparison of fentanyl and droperidol mixture (neuroleptanalgesia II) with morphine on clinical outcomes in unstable angina patients. ( Bronisz, M; Burduk, P; Guzik, P; Jazdon, M; Jordan, MR; Piechocka, M; Rozek, A, 2000)
"TTS fentanyl was shown to be an effective, safe and simple method for long-term pain relief in cancer patients and presents an interesting novel option in the treatment of cancer pain."2.68Transdermal fentanyl in combination with initial intravenous dose titration by patient-controlled analgesia. ( Lehmann, KA; Zech, DF, 1995)
"When fentanyl was given, either more doses were necessary (3."2.67Double-blind comparison of intravenous butorphanol (Stadol) and fentanyl (Sublimaze) for analgesia during labor. ( Atkinson, BD; Christensen, HD; Rayburn, WF; Truitt, LJ; Turnbull, GL; Wlodaver, A, 1994)
"Midazolam was found to be the drug of preference for the majority of patients."2.67Midazolam versus fentanyl as premedication for painful procedures in children with cancer. ( Conner, K; Dickson, N; Luzins, J; McGorray, S; Reilly, K; Sandler, ES; Weyman, C, 1992)
"Alfentanil was used as an adjuvant to midazolam for analgesia in thirty outpatients undergoing colonoscopy."2.67Pain relief for outpatient colonoscopy: a comparison of alfentanil with fentanyl. ( Holloway, AM; Logan, DA, 1990)
"Fentanyl has been FDA approval as an analgesic since 1968 and multiple different fentanyl preparations have been developed over the years."2.66Reasons to avoid fentanyl. ( Behm, B; Davis, MP, 2020)
"This shift in temperature reached a peak effect 11 min after fentanyl administration."2.66A multiple random staircase method of psychophysical pain assessment. ( Dubner, R; Gracely, RH; Lota, L; Walter, DJ, 1988)
"No pain was experienced by patients receiving thiopentone."2.65Comparison of etomidate in combination with fentanyl or diazepam, with thiopentone as an induction agent for general anaesthesia. ( Aromaa, U; Korttila, K; Tammisto, T, 1979)
"Fentanyl was shown to be the most prescribed strong opioid in outpatient settings in Germany, despite not being the first-line choice for chronic pain conditions."2.61Opioid prescription patterns in Germany and the global opioid epidemic: Systematic review of available evidence. ( Neicun, J; Roman-Urrestarazu, A; Rosner, B; Yang, JC, 2019)
" This article illustrates these challenges using a post-authorization safety study (PASS) to assess adverse events (AEs) experienced with fentanyl buccal tablet (FBT) over 3 months of treatment."2.58Challenges of post-authorization safety studies: Lessons learned and results of a French study of fentanyl buccal tablet. ( Bartov, N; Bidollari, I; Gavrielov-Yusim, N; Kaplan, S, 2018)
" There are advantages and disadvantages in using these 2 opioids which are discussed, and potential dosing strategies are outlined."2.58What Parenteral Opioids to Use in Face of Shortages of Morphine, Hydromorphone, and Fentanyl. ( Behm, B; Davis, MP; Fernandez, C; McPherson, ML; Mehta, Z, 2018)
"Mechanistic approaches and multimodal analgesic techniques have been clearly demonstrated to be the most effective pain management strategy to improve outcomes."2.55Analgesia in the surgical intensive care unit. ( Brudney, CS; Ehieli, E; Pyati, S; Yalamuri, S, 2017)
"His pain was scored as a five on a six-point visual analog scale, and it persisted despite routine supportive therapy."2.50[A case of Guillain-Barré syndrome with severe pain successfully controlled with acetaminophen, gabapentin, and parenterally infused fentanyl]. ( Anzai, S; Hashimoto, Y; Nagasawa, K; Suzuki, T, 2014)
"Fentanyl is a potent mu opioid receptor agonist that was discovered to identify an improved human health analgesic over morphine, an opioid frequently associated with histamine-release, bradycardia, hyper- or hypotension, and prolonged postoperative respiratory depression."2.48The history and pharmacology of fentanyl: relevance to a novel, long-acting transdermal fentanyl solution newly approved for use in dogs. ( Clark, TP; Kukanich, B, 2012)
" The purposes of this analysis were to identify and review published data describing the pharmacokinetic properties of rapid-onset fentanyl formulations and to evaluate these properties in view of the temporal dynamic characteristics of BTP in order to help guide medical practice."2.48A review of the pharmacokinetic profile of transmucosal fentanyl formulations. ( Amores, X; Darwish, M; Moore, N; Schneid, H, 2012)
"The pain experienced by cancer patients can be managed in 70-90% of cases by the World Health Organisation protocol for cancer pain."2.47[Solutions for the clinical problems of analgesics for cancer pain treatment in Japan]. ( Kokubun, H; Matoba, M; Yago, K; Yamada, Y, 2011)
"Despite advances in the management of cancer pain, through the application of modern, evidence-based, multimodality management and the availability of new treatment options, recent European surveys have indicated that the diagnosis and treatment of BTcP is still suboptimal."2.47Integrated strategies for the successful management of breakthrough cancer pain. ( Dickman, A, 2011)
"Methadone also has a long elimination half-life (19 [SD 14] hours) and NMDA receptor activity although dose administration is complicated by highly variable morphine equianalgesic equivalence (1 : 2."2.45Pediatric palliative care: use of opioids for the management of pain. ( Anderson, BJ; Craig, F; Michel, E; Zernikow, B, 2009)
"The treatment of BTP in cancer patients receiving opioids is principally based on the use of opioids, preferentially with a short onset."2.45Treatment strategies for cancer patients with breakthrough pain. ( Casuccio, A; Fulfaro, F; Mercadante, S, 2009)
"Fentanyl is a lipophilic, short-acting, synthetic opioid with a piperidine chemical structure."2.45The role of fentanyl in cancer-related pain. ( Prommer, E, 2009)
"Up to 80% of people with cancer experience pain at some time during their illness, and most will need opioid analgesics."2.44Opioids in people with cancer-related pain. ( Quigley, C, 2008)
"Breakthrough pain is a prevalent and serious problem in patients with cancer."2.44A titration strategy is needed to manage breakthrough cancer pain effectively: observations from data pooled from three clinical trials. ( Farrar, JT; Fisher, K; Hagen, NA; Victorino, C, 2007)
"Fentanyl TTS is a promising option for chronic pain control in children."2.44Transdermal fentanyl in childhood and adolescence: a comprehensive literature review. ( Anderson, B; Michel, E; Zernikow, B, 2007)
" FBT utilizes OraVescent technology to improve bioavailability and speed of drug delivery."2.44Fentanyl buccal tablet: faster rescue analgesia for breakthrough pain? ( Hanna, M; Lecybyl, R, 2007)
"Pain is experienced by most cancer patients and represents an important issue in the clinical setting."2.44Oral transmucosal fentanyl citrate in cancer pain management: a practical application of nanotechnology. ( Mystakidou, K; Tsiatas, M; Tsilika, E; Vlahos, L, 2007)
"As a result of improved survival in cancer and the transfer of care from hospital to primary care, community nurses are taking increasing responsibility for the management of patients at all stages of the disease."2.44Actiq: an effective oral treatment for cancer-related breakthrough pain. ( Laverty, D, 2007)
"Pain is a multidimensional symptom that can overshadow all other experiences of both the child and family."2.44The management of pain in children with life-limiting illnesses. ( Friedrichsdorf, SJ; Kang, TI, 2007)
"The fentanyl buccal tablet is a new sugar-free, easily-administered formulation that uses an effervescent drug delivery system to enhance the rate and extent of fentanyl absorption across the buccal mucosa."2.44Fentanyl buccal tablet: rapid relief from breakthrough pain. ( Taylor, DR, 2007)
"Studies of populations with chronic cancer pain have shown a high prevalence of breakthrough pain (BTP), defined as transitory, severe flares of pain that occur on a background of otherwise controlled, persistent pain."2.44Fentanyl buccal tablet. ( Darwish, M; Fine, PG; Messina, J, 2008)
"Pain in older cancer patients is a common event, and many times it is undertreated."2.44Management of pain in the older person with cancer. Part 2: treatment options. ( Bruera, E; Delgado-Guay, MO, 2008)
"Breakthrough pain is a common problem in patients with cancer, and is associated with significant morbidity among this group of patients."2.43Cancer-related breakthrough pain. ( Davies, AN, 2006)
"Persistent pain is present to some degree throughout the day and primarily is controlled with around-the-clock medication."2.42Managing breakthrough pain: a clinical review with three case studies using oral transmucosal fentanyl citrate. ( Palos, G; Rhiner, M; Termini, M, 2004)
" Regular pain assessments combined with appropriate analgesic administration at regular dosing intervals, adjunctive drug therapy for control of adverse effects and associated symptoms, and nonpharmacological interventions are recommended."2.42Cancer pain management in children. ( Mercadante, S, 2004)
"Breakthrough pain affects at least two-thirds of cancer patients at some point during their illness (Portenoy and Hagen, 1990; di Palma et al, 2000)."2.41The role of oral transmucosal fetanyl citrate in the management of breakthrough cancer pain. ( Rees, E, 2002)
" This review analyses the pharmacokinetic properties of transdermal opioid administration in the context of clinical experience, with a focus on fentanyl."2.41Clinical pharmacokinetics of transdermal opioids: focus on transdermal fentanyl. ( Grond, S; Lehmann, KA; Radbruch, L, 2000)
" However, clinicians should realize that the manufacturer's recommendations for equianalgesic dosing of transdermal fentanyl may result in initial doses that are too low in some patients, and in a titration period that is too long."2.41An alternative algorithm for dosing transdermal fentanyl for cancer-related pain. ( Breitbart, W; Chandler, S; Eagel, B; Ellison, N; Enck, RE; Lefkowitz, M; Payne, R, 2000)
"Societal fears of opioid addiction and lack of advocacy are also causal factors in the under-treatment of pediatric pain."2.41Pain management in the critically ill child. ( Nichols, DG; Yaster, M, 2001)
" The dosing interval for these systems is generally 3 days."2.41Treatment of cancer pain with transdermal fentanyl. ( Gourlay, GK, 2001)
"Fentanyl is a synthetic opioid with short-acting analgesic activity after intravenous or subcutaneous administration."2.40Transdermal fentanyl. A review of its pharmacological properties and therapeutic efficacy in pain control. ( Benfield, P; Jeal, W, 1997)
"Tramadol is a centrally acting analgesic drug; it has an agonist effect on mu 1 receptors of opioids and acts also by inhibiting the re-uptake of noradrenaline and serotonine which activates descending monoaminergic inhibitory pathways."2.40[Treatment of pain in oncology]. ( De Conno, F; Polastri, D, 1997)
"Pain is the most feared symptom for patients diagnosed with cancer."2.40Current strategies for pain control. ( Ahmedzai, S, 1997)
"The high prevalence of pain in cancer patients has been appreciated for a long time."2.40Practice guidelines for cancer pain therapy. Issues pertinent to the revision of national guidelines. ( Payne, R, 1998)
"When pain is relieved inadequately by opioid analgesics given in a dose that causes intolerable side effects despite routine measures to control them, treatment with the same opioid by an alternative route or with an alternative opioid administered by the same route should be considered."2.40Opioid rotation for cancer pain: rationale and clinical aspects. ( Mercadante, S, 1999)
"Alfentanil may cause less intense respiratory depression than equianalgesic doses of fentanyl."2.37Alfentanil in anesthesia and analgesia. ( Reitz, JA, 1986)
"Uterine fibroid embolization (UFE) procedures performed from 2013 to 2019 were reviewed."1.91Pain, Nausea, and Hospital Admission after Uterine Fibroid Embolization: A Comparison of 2 Protocols. ( Brahler, T; Hastings, G; Howles-Banerji, G; Kotton, M; Price, A; Singer, D; Wrenn, SJ, 2023)
"Pain is one of the major prehospital symptoms in trauma patients and requires prompt management."1.91Oral transmucosal fentanyl citrate analgesia in prehospital trauma care: an observational cohort study. ( Albrecht, R; Fischer, H; Grünenfelder, A; Hossfeld, B; Pietsch, U; Rüst, CA; Wenzel, V, 2023)
"Inhibition of these neurons alleviates hyperalgesia in male OIH rats but exerts an opposite effect in male control rats."1.91HCN-Channel-Dependent Hyperexcitability of the Layer V Pyramidal Neurons in IL-mPFC Contributes to Fentanyl-Induced Hyperalgesia in Male Rats. ( Gan, S; Li, CH; Luo, F; Wang, X; Zhang, Z; Zhu, P, 2023)
"Pain was measured as the probability of CPOT scores of ≥ 3, and subsequently adjusted based on each patient's baseline."1.91Continuous visualization and validation of pain in critically ill patients using artificial intelligence: a retrospective observational study. ( Kobayashi, N; Murakami, H; Watanabe, K; Yamauchi, M, 2023)
"Opioid-induced hyperalgesia (OIH) is a problem associated with prolonged use of opioids in chronic pain management, and its effective treatment has been hampered by lack of mechanistic evidence."1.72Inhibition of Oligodendrocyte Apoptosis in the Prelimbic Medial Prefrontal Cortex Prevents Fentanyl-induced Hyperalgesia in Rats. ( Cui, LL; Gan, SF; Li, CH; Luo, F; Wang, XX; Xiao, J; Zhang, ZR, 2022)
"There is an urgent need for development of drugs that are able to reverse the adverse effects of opioids on breathing and arterial blood-gas (ABG) chemistry while preserving opioid analgesia."1.72L-NAC reverses of the adverse effects of fentanyl infusion on ventilation and blood-gas chemistry. ( Baby, SM; Bates, JN; Gaston, B; Getsy, PM; Hsieh, YH; Lewis, SJ; Lewis, THJ; May, WJ, 2022)
"Complex regional pain syndrome is a chronic pain condition characterized by autonomic dysfunction, changes in sympathetic and vasomotor activity, and sensory and motor changes."1.72Atypical dermatologic manifestations in complex regional pain syndrome: a case report. ( Abcejo, AS; Langford, B; Pittelkow, TP, 2022)
"Its goal was to see how a transdermal fentanyl patch combined with accelerated recovery after surgery (ERAS) affected the treatment efficacy and analgesic effect of liver cancer, as well as to help patients with liver cancer choose the right analgesic treatment and nursing mode."1.72Effect of Transdermal Fentanyl Patch Combined with Enhanced Recovery after Surgery on the Curative Effect and Analgesic Effect of Liver Cancer. ( Fang, S; Lu, G; Xiao, H; Zhu, H, 2022)
"Fentanyl was introduced in 2013, and by 2019 was given to 39% of patients."1.72Trends in prehospital pain management: two decades of point-of-injury care. ( Avital, G; Bader, T; Benov, A; Chen, J; Fridrich, L; Gelikas, S; Glassberg, E; Nadler, R; Nakar, H; Sorkin, A; Tsur, AM, 2022)
" Data obtained from the electronic medical records included primary outcomes (visual analog scale [VAS] scores and anesthesia satisfaction rate) and secondary outcomes, including vital signs such as heart rate (HR), mean arterial pressure (MAP), total dosage of fentanyl, operation time, X-ray exposure time, Oswestry Disability Index (ODI) scores, and complications."1.72Analgesic effect of epidural anesthesia via the intervertebral foramen approach in percutaneous transforaminal endoscopic discectomy: a retrospective study. ( Cai, Z; Kang, J; Liu, Y; Nie, C; Wang, X; Zhang, J; Zhou, H, 2022)
"In contrast, withdrawal associated thermal hyperalgesia was found only in mice."1.62Divergent profiles of fentanyl withdrawal and associated pain in mice and rats. ( Arakawa, K; Cramer, N; Fox, ME; Jenne, C; Keller, A; Uddin, O, 2021)
"Opioid-induced constipation is the most prevalent adverse effect of opioid drugs."1.62Pharmacological characterization of naloxegol: In vitro and in vivo studies. ( Calò, G; Costanzini, A; De Giorgio, R; Malfacini, D; Neto, JA; Ruzza, C; Sternini, C; Sturaro, C, 2021)
"To assess sedation medication dosage differences between patients with and without opioid use disorder at the time of surgical abortion."1.62Pain medication requirements in patients with opioid use disorder at the time of surgical abortion: An exploratory study. ( Ramanadhan, S; Srikanth, P; White, KO; Woodhams, E, 2021)
" Opioid dosing remains challenging in burn patients, particularly in children, due to the immense variability in efficacy between patients."1.56Characterizing Fentanyl Variability Using Population Pharmacokinetics in Pediatric Burn Patients. ( Grimsrud, KN; Lima, KM; Palmieri, TL; Tran, NK, 2020)
"Cancer pain was observed in 131 of 160 patients with advanced cancer living at home."1.56[Analysis of Symptoms Relieved in Addition to Pain after Administration of Oxycodone or Morphine to Patients with Advanced Cancer Living at Home]. ( Watanabe, K, 2020)
" The purpose of this study is to identify the proportion of new FTS users who had evidence of prior opioid tolerance, by dosage strength, in FDA's Sentinel System."1.51Assessment of prior opioid tolerance among new users of fentanyl transdermal system in FDA's Sentinel System. ( Cocoros, NM; Ju, J; Kornegay, C; Larochelle, MR; Petrone, AB; Popovic, J; Racoosin, JA, 2019)
"Fentanyl has a low molecular weight and is lipophilic making it suitable for transdermal administration."1.51Unusual case of transdermal fentanyl in cachexia. ( Harrison, S; Kay, S; Lam, D; Pickard, J, 2019)
" Surprisingly, respiratory depression, constipation, and opioid withdrawal signs are unchanged or exacerbated, indicating that β-arrestin recruitment does not contribute to the severity of opioid side effects and, hence, predicting that G-protein-biased µ-agonists are still likely to elicit severe adverse effects."1.51Phosphorylation-deficient G-protein-biased μ-opioid receptors improve analgesia and diminish tolerance but worsen opioid side effects. ( Bailey, A; Bateman, JT; Christie, MJ; Kliewer, A; Levitt, ES; Schmiedel, F; Schulz, S; Sianati, S; Williams, JT, 2019)
"Fentanyl was the most common administered analgesic in the trauma subgroup, but significantly less common used by surgeons (p = 0."1.51Differences in pain treatment between surgeons and anaesthesiologists in a physician staffed prehospital emergency medical service: a retrospective cohort analysis. ( Blobner, M; Hofberger, C; Kanz, KG; Kappler, FP; Sattler, J; Schaller, SJ; Schneider, G; Wagner, R, 2019)
"Morphine was associated with a minimal incremental cost-effectiveness ratio of USD 135 per additional case of successful pain relief over fentanyl."1.51Clinical and Economic Analysis of Morphine Versus Fentanyl in Managing Ventilated Neonates With Respiratory Distress Syndrome in the Intensive Care Setting. ( AbouNahia, F; Abushanab, D; Al-Badriyeh, D; Alsoukhni, O, 2019)
"Centipede bites are a constant risk throughout tropical regions and have the rare potential for systemic side effects."1.51Challenges of Remote Medical Care in South Sudan: Centipede Bites. ( Dickson, N; Moles, I; Pallett, SJC, 2019)
"Fentanyl is an opioid analgesic that is available as injection and transdermal patch products for the management of acute and chronic pain."1.51Evaluation of soluble fentanyl microneedles for loco-regional anti-nociceptive activity. ( Ajjarapu, SS; Bae, J; Dhawan, T; Maurya, A; Murthy, SN; Rangappa, S, 2019)
"Infective endocarditis is associated with significant morbidity and mortality, despite advances in diagnosis and treatment strategies."1.51No Fever, No Murmur, No Problem? A Concealed Case of Infective Endocarditis. ( Gorman, M; McCann, M; McKeown, B, 2019)
" Predictors of poorer neurocognitive function were midazolam dosage >3 mg (P<0."1.51Comparison of the Effects of Midazolam/Fentanyl, Midazolam/Propofol, and Midazolam/Fentanyl/Propofol on Cognitive Function After Gastrointestinal Endoscopy. ( Riordan, S; Seck, V; Thompson, R; Wong, S, 2019)
"Fentanyl was administered 9672 times to 4318 patients."1.48Opioid analgesia on the battlefield: a retrospective review of data from Operation HERRICK. ( Hooper, C; Lewis, P; Wright, C, 2018)
"The administration of ketamine during burn wound care using a critical care RN-driven protocol was associated with reduced opioid and benzodiazepine requirements and few adverse effects."1.48CE: Original Research: The Efficacy and Safety of an RN-Driven Ketamine Protocol for Adjunctive Analgesia During Burn Wound Care. ( Baumgartner, L; MacLaren, R; Townsend, N; Winkelman, K, 2018)
" Because of its strong analgesic activity and dosage form, fentanyl has become one of the first choices for severe and moderate pain in clinical practice."1.48Comparison of the use of different analgesics in the course of anesthesia care based on pharmacoeconomics. ( Jing, C; Ping, Y; Qing, J, 2018)
" ABCB1 genotype has been previously associated with patient opioid requirements and may influence fentanyl dosing requirements in critically ill children."1.46ABCB1 genotype is associated with fentanyl requirements in critically ill children. ( Au, AK; Clark, RSB; Conley, YP; Empey, PE; Horvat, CM; Kochanek, PM; Li, L; Poloyac, SM, 2017)
" To evaluate the pharmacokinetic profile of TFS in healthy adult rhesus macaques, we used a 2-period, 2-treatment crossover study of a single topical administration of 1."1.46Pharmacokinetics of a Novel, Transdermal Fentanyl Solution in Rhesus Macaques ( ( Christe, KL; Hill, AE; Knych, HK; Lemoy, MJ; Salyards, GW, 2017)
" There was no difference in pain score reduction; however, repeat dosing was less frequent for patients receiving INF (16% vs."1.46Intranasal Fentanyl and Quality of Pediatric Acute Care. ( Adelgais, KM; Brent, A; Deakyne, S; Massanari, D; Sills, MR; Tong, S; Wathen, J, 2017)
" There were statistically significant differences between new and experienced providers in the distribution of responses for survey items regarding how the importance of treating pain in children was learned, overall comfort with pediatric patients, receiving negative responses from superiors about giving pediatric patients analgesics, and usefulness of the Broselow tape for dosing fentanyl for children."1.46An Assessment of Newly Identified Barriers to and Enablers for Prehospital Pediatric Pain Management. ( Cushman, JT; Jones, CMC; Li, T; Shah, MN; Whitley, DE; Williams, DM, 2017)
" This study investigated the patterns of opioid prescribing and characterized the dosing and duration of opioid use in patients with noncancer and cancer pain."1.46Dose and Duration of Opioid Use in Patients with Cancer and Noncancer Pain at an Outpatient Hospital Setting in Malaysia. ( Choy, LW; Ismail, CR; Rahman, NA; Zin, CS, 2017)
" Nonetheless, careful deliberation is necessary because of the slow effects and difficulty with dosage adjustment."1.43[Use of Transdermal Fentanyl in a Hospital]. ( Kikuchi, N; Sako, A; Watanabe, A; Yoshida, S; Yoshikawa, Y, 2016)
"Fentanyl was preferred for paediatric patients and ketamine was preferentially administered for severe pain by physicians who had more medical experience or had trained in anaesthesia."1.43A two-year retrospective review of the determinants of pre-hospital analgesia administration by alpine helicopter emergency medical physicians to patients with isolated limb injury. ( Albrecht, E; Eidenbenz, D; Hugli, O; Pasquier, M; Taffé, P, 2016)
" For constipation, M6G, fentanyl and buprenorphine were full agonists, oxycodone was a partial agonist, morphine produced a bell-shaped dose-response curve, whereas DPDPE and U69,593 were inactive."1.42In vivo profiling of seven common opioids for antinociception, constipation and respiratory depression: no two opioids have the same profile. ( Kuo, A; Meutermans, W; Smith, MT; Wyse, BD, 2015)
" The objective of this study was to observe whether the dosing time of 6 narcotic analgesics in mice affected their efficacy, pain tolerance and recovery of tolerance."1.42Chronopharmacology of analgesic effect and tolerance induced by six narcotic analgesics in mice. ( Chang, MJ; Jin, JJ; Li, XP; Liu, D; Luo, L; Xu, YJ; Yu, ZQ; Zhang, CL, 2015)
"Pain is believed to be undertreated in patients with dementia; however, no larger studies have been conducted."1.42Frequent use of opioids in patients with dementia and nursing home residents: A study of the entire elderly population of Denmark. ( Astrup, A; Gasse, C; Jensen-Dahm, C; Mortensen, PB; Waldemar, G, 2015)
"Mean fentanyl dose was 734 μg and duration of use was 3."1.42Patient-controlled intranasal fentanyl analgesia: a pilot study to assess practicality and tolerability during childbirth. ( Evans, B; Kerr, D; Taylor, D, 2015)
"We used oxycodone hydrochloride to treat a sharp pain resulting from cataplectic cancer in the jejunal tube, but this provided only limited pain relief."1.42[Efficacy of a fentanyl citrate buccal tablet for esophageal cancer pain management in a patient unable to take oral medication]. ( Baba, H; Fujimura, Y; Nakahara, O; Ohshima, S, 2015)
"The state of opioid consumption among cancer patients has never been comprehensively investigated in Japan."1.42Accuracy of using Diagnosis Procedure Combination administrative claims data for estimating the amount of opioid consumption among cancer patients in Japan. ( Higashi, T; Iwamoto, M; Kawaguchi, T; Matoba, M; Miura, H; Tanaka, S; Yamashita, I; Yoshida, S; Yoshimoto, T, 2015)
"Fentanyl-induced neurotoxicity is an uncommon adverse effect of fentanyl and is seldom seen in pediatric palliative care practice."1.42Fentanyl-Induced Neurotoxicity in Children. ( Deodhar, J; Muckaden, MA; Ostwal, S; Salins, N, 2015)
"One of the key issues in the treatment of pain is to choose the appropriate route and dosage form of analgesics for each individual patient in pain."1.42[Understanding Oral and Nasal Mucosal Absorption of Fentanyl, and Rectal Absorption of Buprenorphine]. ( Kato, Y; Kubota, Y; Shimoyama, M; Shimoyama, N, 2015)
" We describe here an analogue of 1 with an added C-terminal β-glucosylserine residue, Ser(β-Glc)NH2, a modification that has previously been shown to improve bioavailability of opioid peptides."1.40Development of a bioavailable μ opioid receptor (MOPr) agonist, δ opioid receptor (DOPr) antagonist peptide that evokes antinociception without development of acute tolerance. ( Anand, JP; Jutkiewicz, EM; Mosberg, HI; Porter, V; Sobczyk-Kojiro, K; Traynor, JR; Yeomans, L, 2014)
"Morphine was the most frequently prescribed, but the utilization of oxycodone, buprenorphine and fentanyl increased markedly over time."1.40Changes in trends and pattern of strong opioid prescribing in primary care. ( Chen, LC; Knaggs, RD; Zin, CS, 2014)
"Rats treated with fentanyl in RGD liposome and POD device exhibited greater analgesic effect, as compared with the free drug counterpart (AUC(effect) = 1387."1.40Aerosol-stable peptide-coated liposome nanoparticles: a proof-of-concept study with opioid fentanyl in enhancing analgesic effects and reducing plasma drug exposure. ( Ho, RJ; Hoekman, JD; Srivastava, P, 2014)
"Pain was the most common adverse reaction reported."1.40Medication errors related to transdermal opioid patches: lessons from a regional incident reporting system. ( Hägg, S; Holmlund, M; Lövborg, H, 2014)
"Fentanyl was equally effective and 1000× more potent than morphine to inhibit i."1.40Dissociation of immunosuppressive and nociceptive effects of fentanyl, but not morphine, after repeated administration in mice: fentanyl-induced sensitization to LPS. ( Cruz, SL; González-Espinosa, C; Molina-Martínez, LM, 2014)
"A fentanyl patch was also placed for relieving cancer pain, but was removed 4 months later because the pain disappeared."1.40[A case of recurrent colon cancer with improvement in prognosis and cancer pain after surgical intervention]. ( Fujisaki, S; Sakurai, K; Takashina, M; Takayama, T; Tomita, R, 2014)
" Opioid dosage was indicative of syndrome severity and correlated with other physiological parameters measured."1.39Long-term analysis of Irukandji stings in Far North Queensland. ( Carrette, TJ; Seymour, JJ, 2013)
"Pain was associated with younger age (p < 0."1.38The burden of endoscopic retrograde cholangiopancreatography (ERCP) performed with the patient under conscious sedation. ( Jeurnink, SM; Kuipers, E; Siersema, P; Steyerberg, E, 2012)
"loperamide was abolished by i."1.38Relative contributions of peripheral versus supraspinal or spinal opioid receptors to the antinociception of systemic opioids. ( Al-Khrasani, M; Fürst, S; Khalefa, BI; Mousa, SA; Schäfer, M; Shaqura, M, 2012)
"Before intratracheal suctioning, patients had RASS scores of -1."1.38Assessment of pain in sedated and mechanically ventilated patients: an observational study. ( Hamers, JP; Hantikainen, V; Jakob, SM; Jeitziner, MM; Rohrer, O; Schwendimann, R, 2012)
" Maximum venous concentration and area under the concentration curve were approximately two-fold lower in the patient group for an equivalent dose, suggesting either reduced bioavailability or increased clearance: maximum venous concentration 0."1.38Pharmacokinetics of oxycodone after subcutaneous administration in a critically ill population compared with a healthy cohort. ( Chapman, MJ; Charlton, CS; Fajumi, AO; Krishnamurthy, RB; Lai, S; Ludbrook, GL; Macintyre, PE; Martinez, AM; McConnell, H; O'Connor, SN; Ong, J; Ousley, RM; Upton, RN, 2012)
"Emergent adult trauma patients were included with an initial prehospital Glasgow Coma Scale score of ≥13 and systolic blood pressure >90 mm Hg."1.38Safety of prehospital intravenous fentanyl for adult trauma patients. ( Byyny, RL; Colwell, CB; Gravitz, C; Haukoos, JS; Liao, MM; McVaney, KE; Soriya, GC, 2012)
"Von Frey filaments were used to measure mechanical allodynia of the hind paw and abdomen."1.38Involvement of spinal orexin A in the electroacupuncture analgesia in a rat model of post-laparotomy pain. ( Feng, XM; Jiang, JW; Mao-Ying, QL; Mi, WL; Wang, YQ; Wang, ZF; Wu, GC; Xia, F; Xiao, S, 2012)
" Although intravenously administered morphine can readily provide rapid and effective prehospital analgesia, oral transmucosal fentanyl citrate (OTFC) is a safe alternative that does not require intravenous access."1.38Safety and efficacy of oral transmucosal fentanyl citrate for prehospital pain control on the battlefield. ( Fowler, M; Kotwal, RS; McGhee, L; McManus, JG; Pennardt, A; Talbot, TS; Wedmore, IS, 2012)
"This study involved 320 cancer patients from four Northern European countries."1.37Multi-centre European study of breakthrough cancer pain: pain characteristics and patient perceptions of current and potential management strategies. ( Andersen, S; Buchanan, A; Damkier, A; Davies, A; Nauck, F; Radbruch, L; Sjolund, KF; Stenberg, M; Vejlgaard, T; Zeppetella, G, 2011)
" First of all, once assessed that all drugs induced dose-related antinociceptive effects, they were mixed in fixed ratio (1:1) combinations and a synergistic drug-drug interaction was obtained in all circumstances."1.37Fentanyl-trazodone-paracetamol triple drug combination: multimodal analgesia in a mouse model of visceral pain. ( Ciruela, F; Fernández, A; Fernández-Dueñas, V; Planas, E; Poveda, R; Sánchez, S, 2011)
" In the switching study DDD indicated a reduction in analgesic dosing and OMEQ an increase when switching from WHO step II to III."1.37Choosing the unit of measurement counts: the use of oral morphine equivalents in studies of opioid consumption is a useful addition to defined daily doses. ( Borchgrevink, P; Dale, O; Fredheim, O; Hamunen, K; Mellbye, A; Svendsen, K, 2011)
"Fentanyl is an opioid initially developed for parenteral administration."1.36Formulations of fentanyl for the management of pain. ( Grape, S; Lauer, S; Schug, BS; Schug, SA, 2010)
" To determine the dosing frequency of sustained-release opioids (morphine, oxycodone, and transdermal fentanyl) and the prevalence of end-of-dose failure in clinical practice, a patient-reported survey was performed."1.36The dosing frequency of sustained-release opioids and the prevalence of end-of-dose failure in cancer pain control: a Korean multicenter study. ( Ahn, JS; Kim, DY; Kim, SY; Ryoo, BY; Shin, DB; Song, HS; Yim, CY, 2010)
"Breakthrough pain is defined as transitory flares of pain."1.36Recent development in therapeutics for breakthrough pain. ( Davis, MP, 2010)
"Incidence of newly diagnosed cancers is also the second highest in the Gulf with 11%."1.36Historical perspectives and trends in the management of pain for cancer patients in oman. ( Mahfudh, SS, 2010)
" We show that the opioid Fentanyl, and its structurally similar sedative Zolpidem, can be embedded into metakaolin based geopolymer pellets to provide prolonged release dosage forms with mechanical strengths of the same order of magnitude as that of human teeth."1.36Mechanically strong geopolymers offer new possibilities in treatment of chronic pain. ( Bredenberg, S; Engqvist, H; Forsgren, J; Jämstorp, E; Strømme, M, 2010)
"Fentanyl patch is an alternative for children who cannot tolerate morphine."1.35Fentanyl patch for stable chronic pain in children: new indication. Used fentanyl patches should be handled with care. ( , 2008)
"The femur bone cancer pain model was developed by implanting mouse osteolytic tumor cells (NCTC 2472) into the intramedulla of the femur in C3H/HeN mice."1.35Oxycodone-induced analgesic effects in a bone cancer pain model in mice. ( Ito, H; Kato, A; Kihara, T; Matsumoto, M; Minami, K; Narita, M; Orita, S; Suzuki, T; Tomii, T, 2008)
"Pain is an important and often under-treated symptom of life-threatening illness."1.35[Analgesics and palliative care]. ( Mathieu, N; Tuna, T, 2008)
"(B) Fentanyl was administered in situ to investigate the interaction with 8-OH-DPAT on phrenic nerve activity and nociceptive CFR."1.35The counteraction of opioid-induced ventilatory depression by the serotonin 1A-agonist 8-OH-DPAT does not antagonize antinociception in rats in situ and in vivo. ( Dutschmann, M; Guenther, U; Hoeft, A; Manzke, T; Putensen, C; Wrigge, H; Zinserling, J, 2009)
"Buprenorphine displays attributes of opioids, but also some features distinct from them."1.35Identification of an additional supraspinal component to the analgesic mechanism of action of buprenorphine. ( Ding, Z; Raffa, RB, 2009)
"MK-801 blocked and reversed hyperalgesia caused by the acute injection and continuous infusion of fentanyl, respectively, in naltrexone-treated CD-1 mice, indicating the contribution of NMDA receptors to fentanyl hyperalgesia."1.35Acute and chronic fentanyl administration causes hyperalgesia independently of opioid receptor activity in mice. ( Arout, C; Caldwell, M; Dahan, A; Kest, B; Waxman, AR, 2009)
"Fentanyl-induced hyperalgesia and antinociception after systemic administration has been shown in previous clinical and experimental studies."1.35Magnesium modifies fentanyl-induced local antinociception and hyperalgesia. ( Gunay, I; Gunes, Y; Mert, T; Ozcengiz, D, 2009)
"Cancer pain is common, occurring in up to 60% of patients and opioid conversion may be required for effective pain management."1.35Inconsistencies in opioid equianalgesic ratios: clinical and research implications. ( Kutner, JS; Linnebur, SA; O'Bryant, CL; Yamashita, TE, 2008)
"Children with solid tumors outside the central nervous system were likely to receive more opioids, be given multiple different opioids, and receive opioids in the last month."1.35Opioid use in palliative care of children and young people with cancer. ( Childs, M; Collins, GS; Goldman, A; Hain, R; Hewitt, M, 2008)
"Pain was well controlled."1.35Fentanyl-induced neurotoxicity and paradoxic pain. ( George, ML; Okon, TR, 2008)
"Assisted sedation is a safe and easy method for pain free PVP procedures."1.35Assisted sedation: a safe and easy method for pain-free percutaneous vertebroplasty. ( Andreula, C; Della Puppa, A; Frass, M, 2008)
" Demographic data, time in ED, and dosage of each medication given were abstracted."1.35Inadequate provision of postintubation anxiolysis and analgesia in the ED. ( Bonomo, JB; Butler, AS; Lindsell, CJ; Venkat, A, 2008)
"We present two cases of scorpion envenomation with different and rare clinical situations with a short review of the literature."1.35Unusual presentations of scorpion envenomation. ( Demir, M; Ranu Alpay, N; Satar, S; Sebe, A; Topal, M, 2008)
"fentanyl was naloxone reversible and potentiated exclusively in inflamed and NGF-treated paws."1.34Nerve growth factor governs the enhanced ability of opioids to suppress inflammatory pain. ( Cheppudira, BP; Fischer, O; Hellweg, R; Hofmann, J; Mousa, SA; Schäfer, M; Shaqura, M, 2007)
"Neuropathic pain is associated with several sensory abnormalities, including allodynia as well as spontaneous pain."1.34Opioid self-administration in the nerve-injured rat: relevance of antiallodynic effects to drug consumption and effects of intrathecal analgesics. ( Buechler, NL; Eisenach, JC; Kim, SA; Martin, TJ; Porreca, F, 2007)
"Fifty percent N2O strongly reduced hyperalgesia induced by a first inflammation and its enhancement by fentanyl, and prevented exaggerated hyperalgesia induced by second inflammatory pain or NNES."1.34Nitrous oxide (N2O) prevents latent pain sensitization and long-term anxiety-like behavior in pain and opioid-experienced rats. ( Bessière, B; Contarino, A; Laboureyras, E; Laulin, JP; Richebé, P; Simonnet, G, 2007)
"Many Japanese cancer patients experience severe pain although they and their families hope to be pain free at the end of their lives."1.34Toward freedom from cancer pain in Japan. ( Otsuka, K; Yasuhara, H, 2007)
"A dose-response relationship between fentanyl and artificial feeding has not been reported elsewhere."1.33The impact of intrapartum analgesia on infant feeding. ( Bradshaw, C; Emery, S; Friswell, W; Jordan, S; Watkins, A, 2005)
"Fentanyl was provided frequently, with good effect and minimal cardiorespiratory consequence."1.33Fentanyl trauma analgesia use in air medical scene transports. ( Biddinger, PD; Harrison, T; Rago, O; Thomas, SH; Wedel, SK, 2005)
" The bioavailability of fentanyl was statistically different according to patient age."1.33Inter- and intra-individual variability in transdermal fentanyl absorption in cancer pain patients. ( Astre, C; Bressolle, F; Caumette, L; Coulouma, R; Culine, S; Garcia, F; Pinguet, F; Solassol, I; Thézenas, S, 2005)
"However, if pain is unmanageable in the outpatient department, we believe that options include hospital admission, using the contained method of application or, in the worst case scenario, cessation of treatment."1.33Determining pain levels in patients treated with maggot debridement therapy. ( Budding, T; Oskam, J; Steenvoorde, P, 2005)
" To analyze possible interaction between these two drugs, a dose-response curve to fentanyl plus a fixed dose of R-(alpha)-methylhistamine (0."1.33Synergistic interaction between fentanyl and the histamine H3 receptor agonist R-(alpha)-methylhistamine, on the inhibition of nociception and plasma extravasation in mice. ( Fernández, A; Fernández-Dueñas, V; Planas, E; Poveda, R; Puig, MM; Sánchez, S, 2006)
"Pain affects many cancer patients, and in advanced stages of the disease it can significantly affect the quality of their lives."1.33Three-cycle fentanyl patch system significantly improves pain control in gynecologic cancer. ( Hayashi, M; Kanamori, C; Kanamori, T; Kanzaki, H; Yorioka, H, 2006)
"Fentanyl is a synthetic, lipophilic opioid, more potent than morphine, and achieves peak effects after intravenous administration in 5 minutes."1.32Intravenous fentanyl for cancer pain: a "fast titration" protocol for the emergency room. ( Martins, M; Soares, LG; Uchoa, R, 2003)
"For patients without cancer, rates of therapy switching at 6 months were 10."1.32Therapy switching in patients receiving long-acting opioids. ( Berger, A; Delea, TE; Goodman, S; Hoffman, DL; Oster, G; Seifeldin, R, 2004)
"Morphine side effects were reduced in some patients who changed to transdermal fentanyl, but there was no reduction in those who needed high-dose morphine for rescue analgesia."1.32A study of transdermal fentanyl in cancer pain at Aichi-Cancer Center. ( Hasegawa, M; Hosoda, R; Kamiya, Y; Kato, K; Mizaki, T; Nitta, M; Yamazaki, S, 2004)
"Fentanyl was discontinued, fluids were restricted, and 3% saline was started."1.31Fentanyl-associated syndrome of inappropriate antidiuretic hormone secretion. ( Afrin, LB; Hall, PD; Kokko, H, 2002)
"Dextromethorphan produced lower ED(50) values for morphine, fentanyl and sufentanil but exerted no effect on the potency of SNC80 or U50,488H."1.31Dextromethorphan and ketamine potentiate the antinociceptive effects of mu- but not delta- or kappa-opioid agonists in a mouse model of acute pain. ( Baker, AK; Hoffmann, VL; Meert, TF, 2002)
"The initial hyperalgesia induced by 0."1.31Large-amplitude 5-HT1A receptor activation: a new mechanism of profound, central analgesia. ( Assié, MB; Bardin, L; Carilla-Durand, E; Colpaert, FC; Cosi, C; Koek, W; Pauwels, PJ; Tarayre, JP; Vacher, B; Wiesenfeld-Hallin, Z; Xu, XJ, 2002)
"Clonidine was also evaluated in combination with ketamine and dextromethorphan."1.31Interactions of NMDA antagonists and an alpha 2 agonist with mu, delta and kappa opioids in an acute nociception assay. ( Baker, AK; Hoffmann, VL; Meert, TF, 2002)
"In untreated mice, morphine, fentanyl, clonidine, oxymetazoline, desipramine and lidocaine, but not MK801, produced dose-related antinociception when tested using a 55 degrees C water tail-flick test."1.31Pharmacologic reversal of pertussis toxin-induced thermal allodynia in mice. ( Shannon, HE; Womer, DE, 2000)
" As assessed by cumulative dose-response approach in the tail-flick test, administration of 10 mg kg(-1) morphine bid s."1.31Selective agonist of group II glutamate metabotropic receptors, LY354740, inhibits tolerance to analgesic effects of morphine in mice. ( Kozela, E; Pilc, A; Popik, P, 2000)
"Ohmefentanyl is a very potent and highly selective agonist for mu-opioid receptors."1.31Analgesic activity and opioid receptor selectivity of stereoisomers of ohmefentanyl isothiocyanate. ( Chen, BY; Chen, XJ; Chi, ZQ; Jin, WQ; Zhu, YC, 2001)
"Fentanyl has a 7 gram usage versus a 100 gram INCB allocation."1.31Opioid use in chronic pain management in the Philippines. ( Espinosa, EL; Harder, SM; Javier, FO; Magpantay, LA; Unite, MA, 2001)
"Most patients suffered from cancer pain and only 11 patients had chronic pain from non-malignant disease."1.31Transdermal fentanyl for the management of cancer pain: a survey of 1005 patients. ( Brunsch-Radbruch, A; Grond, S; Lehmann, KA; Petzke, F; Radbruch, L; Sabatowski, R, 2001)
"Ketamine has been found to exert antinociceptive effects in animals and to be analgesic at subanaesthetic doses in humans."1.31Potentiation by ketamine of fentanyl antinociception. I. An experimental study in rats showing that ketamine administered by non-spinal routes targets spinal cord antinociceptive systems. ( Bajunaki, E; Goodchild, CS; Nadeson, R; Tucker, A, 2002)
"Yet, surveys of nurses' knowledge of cancer pain management reveal serious knowledge deficits that could adversely affect the care of patients with cancer pain."1.30Nurses' knowledge about equianalgesia and opioid dosing. ( Ferrell, BR; McCaffery, M, 1997)
"Propofol and fentanyl were administered via computer-assisted continuous infusion to provide stable concentrations and to allow equilibration between plasma-blood and effect-site concentrations."1.30Reduction by fentanyl of the Cp50 values of propofol and hemodynamic responses to various noxious stimuli. ( Ikeda, K; Kazama, T; Morita, K, 1997)
"Morphine was approximately 7440 times less potent than dihydroetorphine while heroin and fentanyl were approximately 163."1.30Anti-allodynic actions of intravenous opioids in the nerve injured rat: potential utility of heroin and dihydroetorphine against neuropathic pain. ( Hairston, CT; Harris, LS; Lutz, PO; Martin, TJ; Porreca, F, 1998)
"Postfentanyl vital signs were reviewed for evidence of hemodynamic or ventilatory compromise."1.30Prehospital fentanyl analgesia in air-transported pediatric trauma patients. ( DeVellis, P; Stein, JP; Thomas, SH; Vinci, RJ; Wedel, SK, 1998)
"To assess the effect of opioid substitution (substituting one member of the opioid class for another) on the incidence and severity of adverse effects in palliative care patients who experience unacceptable, refractory adverse effects when taking an opioid drug."1.30Opioid substitution to reduce adverse effects in cancer pain management. ( Ashby, MA; Jackson, KA; Martin, P, 1999)
"The patients included 14 intravenous drug abusers, five of whom were on methadone maintenance."1.29Evaluation of recalcitrant pain in HIV-infected hospitalized patients. ( Anand, A; Carmosino, L; Glatt, AE, 1994)
"5 h Tmax was observed."1.29In vivo iontophoresis of fentanyl and sufentanil in rats: pharmacokinetics and acute antinociceptive effects. ( Préat, V; Thysman, S, 1993)
" Recommendations for managing opioid-induced muscle hyperactivity include reduction of the opioid dosage and/or administration of clonazepam therapy."1.29Opioid-induced muscle activity: implications for managing chronic pain. ( Levitt, R; Steen, PD; Sylvester, RK, 1995)
"Shivering and hiccoughing were noted in two and four cases, respectively."1.29Methohexital infusion technique for conscious sedation. ( Buckley, M; Johns, FR; Ziccardi, VB, 1996)
"The triggering of phantom limb pain by subarachnoid or epidural anaesthesia has been well described leading to the suggestion that neuraxial regional anaesthesia is relatively contraindicated in lower limb amputees."1.29Regional anaesthesia for repeat Caesarean section in a patient with phantom limb pain. ( Carrie, LE; Glynn, CJ; Uncles, DR, 1996)
" Although anecdotal experience exists concerning the use of fentanyl PCA in adults, dosing guidelines in children must depend on consideration of the current narcotic regimen and the use of equipotent doses of fentanyl."1.28Patient-controlled analgesia with fentanyl in children. ( Baker, DK; Tobias, JD, 1992)
"This is a report of the results of 25 experiments in five rats investigating the dose-response relationship for the antinociceptive effects of chlordiazepoxide given intrathecally in the dose range 0."1.28Spinally mediated antinociception following intrathecal chlordiazepoxide--further evidence for a benzodiazepine spinal analgesic effect. ( Boulter, N; Gent, JP; Goodchild, CS; Serrao, JM, 1991)
" On the basis of our dose-response data, we suggest that, in mice, kappa and mu, but not delta, opioid receptors modulate tonic pain perception at both spinal and supraspinal loci."1.28Tonic pain perception in the mouse: differential modulation by three receptor-selective opioid agonists. ( Cowan, A; Murray, CW, 1991)
" The A50 (dose producing 50% MPE) for each drug or drug combination was determined from the dose-response curve."1.28Antinociceptive interaction between opioids and medetomidine: systemic additivity and spinal synergy. ( Bagley, J; Harris, S; Lin, BS; Lloyd, P; Messineo, E; Ossipov, MH, 1990)
" Flumazenil (Ro 15-1788) administration caused a parallel shift to the right of the dose-response curve for midazolam spinal analgesia."1.28On the mechanism by which midazolam causes spinally mediated analgesia. ( Edwards, M; Gent, JP; Goodchild, CS; Serrao, JM, 1990)
"We report on a patient with acute pancreatitis whose pain was resistant to simultaneous administration of morphine, procaine and Buscopan."1.28[The value of epidural analgesia in acute pancreatitis]. ( Borgeat, A; Chanson, C; Nicolet, A; Schwander, D, 1990)
" dose-response curves for the effect of the chronic drug given as a bolus."1.28Potency of infused spinal antinociceptive agents is inversely related to magnitude of tolerance after continuous infusion. ( Stevens, CW; Yaksh, TL, 1989)
"Naloxone did, however, suppress FI and WI following deprivation and inhibited the recovery of body weight thereafter."1.27Long-term blockade of mu-opioid receptors suggests a role in control of ingestive behaviour, body weight and core temperature in the rat. ( Millan, MJ; Morris, BJ, 1988)
"However in the acute postoperative pain group other factors such as depletion of endorphins by drugs used for anesthesia or due to surgical stress cannot be excluded."1.26[Measurement of endorphins in human cerebrospinal fluid. Comparative study of various groups of patients]. ( Laorden, ML; Miralles, F; Olaso, MJ; Puig, MM, 1982)
"Both approaches give insight into the results: the technique copes with biological variability; anticipating pain induced by fear disappears; the feedback strategy works well and patients adapt to a wide range in prescriptions; intermittent administration makes more efficient use of the analgesic; an optimal result is demonstrated in studies comparing on-demand analgesia with the normal IM-regime and epidural analgesia; continuity in pain relief can be obtained in routine clinical practice."1.26Postoperative pain relief by demand analgesia. ( Brugmans, J; Peeters, M, 1980)
"The authors consider endotracheal narcosis with nitrous oxide combined with fractional injections of phentanyl and seduxen of phentanyl and droperidol to be a method of choice."1.26[Characteristics of combined nitrous oxide nacrosis and premedication with phentanyl and droperidol or phentanyl and seduxen in patients with pain syndrome caused by blood vessel diseases of the lower extremities]. ( Korzh, OB; Timchuk, ID, 1979)
"Xylazine was significantly more effective in obtunding deep pain (P less than 0."1.26Objective tests of analgesic drugs in ponies. ( Lumb, WV; Pippi, NL, 1979)

Research

Studies (1,200)

TimeframeStudies, this research(%)All Research%
pre-1990116 (9.67)18.7374
1990's210 (17.50)18.2507
2000's415 (34.58)29.6817
2010's343 (28.58)24.3611
2020's116 (9.67)2.80

Authors

AuthorsStudies
Mosberg, HI1
Yeomans, L1
Anand, JP1
Porter, V1
Sobczyk-Kojiro, K1
Traynor, JR1
Jutkiewicz, EM1
Kondo, A1
Murakami, T1
Fujii, T2
Tatsumi, M1
Ueda-Sakane, Y1
Ueda, Y1
Yamauchi, I1
Ogura, M1
Taura, D1
Inagaki, N1
Lugli, L1
Spada, C1
Garetti, E3
Guidotti, I1
Roversi, MF1
Della Casa, E1
Bedetti, L1
Lucaccioni, L1
Pugliese, M1
Ferrari, F2
Iughetti, L1
Lago, P3
Berardi, A1
Barker, KE1
Lecznar, AJ1
Schumacher, JM1
Morris, JS1
Gutstein, HB1
Carenzo, L1
McDonald, A1
Grier, G1
Madathil, S1
Thomas, D1
Chandra, P1
Agarwal, R1
Sankar, MJ1
Thukral, A1
Deorari, A1
Oto, Y1
Momo, K1
Uchikura, T1
Tanaka, K3
Sasaki, T1
Aminnejad, R1
Hormati, A1
Shafiee, H1
Alemi, F1
Hormati, M1
Saeidi, M1
Ahmadpour, S1
Sabouri, SM1
Aghaali, M1
Huang, SM1
Hsu, H1
Hii, IH1
Chang, CH2
Qiu, J1
Xie, M1
Donnenfeld, ED1
Mychajlyszyn, D1
Mychajlyszyn, A1
Stein, R1
Wang, XX1
Cui, LL1
Gan, SF1
Zhang, ZR1
Xiao, J1
Li, CH2
Luo, F2
Sirohiya, P1
Kumar, V1
Mittal, S1
Gupta, N1
Garg, R2
Bharati, SJ1
Mishra, S1
Hadda, V1
Mohan, A1
Sagiraju, HKR1
Bhatnagar, S1
Madan, K1
Latev, A1
Baer, J1
Sharpe, S1
Gupta, C1
Feliciano, C1
Friedman, BW1
Zhou, S1
Bi, J1
Zhao, W1
Zhao, J1
Wan, H1
Wang, S1
Bilel, S1
Azevedo Neto, J1
Arfè, R1
Tirri, M1
Gaudio, RM1
Fantinati, A1
Bernardi, T1
Boccuto, F1
Marchetti, B1
Corli, G1
Serpelloni, G1
De-Giorgio, F1
Malfacini, D2
Trapella, C1
Calo', G1
Marti, M1
Hayashi, M3
Shimamura, Y1
Shiroshita, A1
Bahrami, F2
Rossi, RM2
Defraeye, T2
Tang, LJ1
Han, J1
Feng, YJ1
Pu, CX1
Zhang, Y4
Wallen, TE1
Elson, NC1
Singer, KE1
Hayes, HV1
Salvator, A1
Droege, CA1
Nomellini, V1
Pritts, TA1
Goodman, MD1
Xia, W1
Yang, C2
Weitzman, ER1
Kossowsky, J1
Blakemore, LM1
Cox, R1
Dowling, DJ1
Levy, O1
Needles, EW1
Levy, S1
Wang, JJ1
Teng, SF1
Chu, YR1
Chu, CC1
Ho, CH1
Chu, LL1
Thirunavukarasu, AJ1
Hassan, R1
Savant, SV1
Hamilton, DL1
Getsy, PM1
Baby, SM2
May, WJ2
Lewis, THJ1
Bates, JN3
Hsieh, YH1
Gaston, B1
Lewis, SJ2
Langford, B1
Pittelkow, TP1
Abcejo, AS1
Ruffin, TB1
Salinero, E1
Papa, L1
Cramm, K1
Florez, C1
Chen, JG1
Ramirez, J1
Lynch, TV1
Callas, PW1
Peterson, TD1
Schlein, SM1
Pyle, A1
Kelty, E1
Sanfilippo, F4
Murray, K1
Preen, D1
Zhu, H2
Xiao, H1
Lu, G1
Fang, S1
Chin, J1
McGrath, M1
Lokken, E1
Upegui, CD1
Prager, S1
Micks, E1
Azarfar, A1
Ravanshad, Y1
Golsorkhi, M1
Zahiri, E1
Gharavi Fard, M1
Akhondi, M1
Ghodsi, A1
Ravanshad, S1
Efune, PN1
Rebstock, SE1
Nihadha, PM1
Chugh, A1
Kaur, A2
Kumar, S1
Naveen, KH1
Bhatia, PK1
Kumar, P1
Chaudhry, K2
Puig, S1
Shelton, MA1
Barko, K1
Seney, ML1
Logan, RW1
Maarof, SR1
Ahmad, CA1
Atkins, L1
Devol, EB1
Hussain, A1
Abdullah, KL1
Hudson, IL1
Staudt, AM1
Burgess, M1
Hinojosa-Laborde, C3
Schauer, SG1
Newberry, RK1
Ryan, KL2
VanFosson, CA1
Campos-Pérez, W1
Ramírez-Plascencia, L1
Pérez-Robles, M1
Rivera-Valdés, JJ1
Sánchez-Muñoz, P1
Pérez-Vargas, L1
González-Landeros, D1
Cuevas, JHM1
Martínez-López, E1
Nakar, H1
Sorkin, A1
Nadler, R1
Tsur, AM1
Gelikas, S1
Avital, G1
Glassberg, E1
Bader, T1
Fridrich, L1
Chen, J2
Benov, A1
Bueno-Serrano, G1
Alcoba-García, MP1
Tabares-Jiménez, J1
González-López, R1
Llanos-Jiménez, L1
Mahillo-Fernández, I1
González-Enguita, C1
Monsereenusorn, C2
Malaithong, W1
Lertvivatpong, N1
Photia, A1
Rujkijyanont, P2
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Morrison, JD1
Dosiak, J1
Ferrari, HA1
Fuson, RL1
Dent, SJ1
Brodzińska, K1
Skubiszyńska, A1
Szmydt, W1
Knape, H1
Litarczek, G1
Fagarasanu, R1
Balan, A1
Gorunescu, E1
Nedelou, C1
Albus, K1
Metys, J1
Schubert, P1
Teschemacher, H1
Baldy-Moulinier, M1
Ingvar, DH1
Gerardi, AU2
Cardini, L2
Green, CD1
Zattoni, J1
Giunta, F1
Fava, E1

Clinical Trials (114)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Ketamine Versus Fentanyl for Surgical Abortions: A Randomized Controlled Noninferiority Trial[NCT04871425]Phase 4110 participants (Actual)Interventional2021-04-27Completed
A Comparison of Opioid-containing Anesthesia Versus Opioid-free Anesthesia Using the Cortínez-Sepúlveda Model on Differential Cytokine Responses in Patients Undergoing Gastric Bypass Surgery[NCT04854252]40 participants (Actual)Interventional2020-11-12Completed
Gabapentin as an Adjunct for Pain Management During Dilation and Evacuation: A Double-blind Randomized Controlled Trial[NCT03635905]Phase 4130 participants (Actual)Interventional2017-05-26Completed
Effect of the Programmed Intermittent Epidural Bolus Versus Continuous Epidural Infusion on the Quality of Postoperative Recovery in Patients Undergoing VATS Lobectomy[NCT05930405]252 participants (Anticipated)Interventional2023-10-01Recruiting
Organ Protective Effect of Histamine H1 Receptor Antagonist In Patients With Severe Burns: A Clinical Study[NCT06126991]Phase 1/Phase 232 participants (Anticipated)Interventional2023-11-01Recruiting
A Randomized Controlled Trial to Evaluate the Impact of Integrated Preoperative Fascia Iliaca Compartment Block (FICB) for Fast-track Surgery in Elderly Hip Fracture[NCT05857462]420 participants (Anticipated)Interventional2023-05-31Recruiting
Effect of Three Different Sensory Interventions on Pain Level During Heel Blood Collection in Term Infant: A Randomized Controlled Study[NCT05526378]120 participants (Actual)Interventional2022-12-22Completed
The Effect of usıng Breast mılk pacıfıer, Sucrose pacıfıer and pacıfıer ın reducıng the paın That Occurs durıng orogastrıc Tube ınsertıon ın Preterm Newborns[NCT05430100]73 participants (Actual)Interventional2022-07-10Completed
Determination of Analgesic Equipotent Doses of Inhaled Metoxyflurane vs. Intravenous Fentanyl Using Cold Pressor Test (CPT) in Volunteers: A Randomized, Double Blind, Placebo-controlled Crossover Study.[NCT03894800]Phase 412 participants (Actual)Interventional2019-04-23Completed
A Survey of Management of Analgesia, Sedation and Delirium in ICU Patients in China[NCT04217915]800 participants (Anticipated)Observational2021-07-12Recruiting
A pRospective, Case-controlled Evaluation of oLIceridine for Moderate or sEVEre Pain in Patients With Acute Burn Injuries. (RELIEVE)[NCT05465226]Phase 431 participants (Actual)Interventional2023-04-01Completed
Nitrous Oxide Versus Intravenous Sedation for Anesthesia[NCT02755090]39 participants (Actual)Interventional2016-07-31Completed
A Randomized Controlled Trial of Intranasal Sub-dissociative Dosing of Ketamine Compared to Intranasal Fentanyl for Treatment of Pain Associated With Acute Extremity Injuries in Children[NCT02778880]Phase 390 participants (Actual)Interventional2016-03-31Completed
Is There an Ideal Dose of Intravenous Fentanyl in the Prehospital Setting: A Prospective Cluster-randomized Comparison of 2 vs. 3 μg/kg/Transport[NCT02914678]7,093 participants (Actual)Interventional2016-10-31Completed
Sedation, ANalgesia and Delirium MANagement: a Study of Medical, Surgical, Trauma, and Neuro-intensive Care Patients and a COVID-19 Sub-study.[NCT05027217]3,421 participants (Actual)Observational2022-01-01Completed
Efficacy and Safety of Continuous Infusion of Fentanyl for Pain Control in Preterm Newborn on Mechanical Ventilation[NCT00571636]Phase 3128 participants (Anticipated)Interventional2007-12-31Completed
Comparison of Controlled-release Oxycodone to Control Chemoradiotherapy-induced Moderate or Severe Oral Mucositis Pain in Nasopharyngeal Carcinoma Patients[NCT03045484]70 participants (Anticipated)Interventional2016-05-31Recruiting
Efficacy and Safety of Opioid Analgesics as a Preventive Treatment of Procedural Pain Associated With Turning Among Critically Ill Patients Under Mechanical Ventilation. A Controlled Clinical Trial Comparing Placebo and Fentanyl[NCT01950000]Phase 475 participants (Actual)Interventional2011-03-31Completed
Comparison of the Effects of Esketamine, Sufentanil, or Lidocaine Combined With Propofol on Tussis Reflection During Upper Gastroscopy: a Randomised, Two Centre, Three-blind, Controlled Trial[NCT05497492]400 participants (Anticipated)Interventional2022-11-05Recruiting
Effects of Social Presence and Perception in Virtual Reality on Pain[NCT03157362]105 participants (Actual)Interventional2018-02-01Completed
Intranasal Sufentanil for Analgesia of Severe Sickle Cell Vaso-occlusive Pain Crisis in the Pediatric Emergency Department: a Double Blind Randomized Versus Placebo Controlled Trial[NCT06181695]Phase 3182 participants (Anticipated)Interventional2024-05-02Not yet recruiting
Effect of a Perioperative Opioid Free Anesthesia-Analgesia (OFA-A) Strategy on Surgical Stress Response in Elective Open Abdominal Aortic Aneurysm Repair: A Prospective Randomized Study[NCT04894864]Phase 440 participants (Anticipated)Interventional2020-10-08Recruiting
Effect of Intraoperative and Post-operative Opioids on Persistent Opioid Use in the Surgical Patient[NCT03367988]Phase 2/Phase 3100 participants (Anticipated)Interventional2018-12-01Recruiting
Routine Versus on Demand Administration of Fentanyl in Colonoscopy: A Multi-centre Randomized Controlled Trial[NCT01786434]119 participants (Actual)Interventional2012-12-10Completed
Randomized Controlled Trial of Intranasal Ketamine Compared to Intranasal Fentanyl for Analgesia in Children With Suspected, Isolated Extremity Fractures in the Pediatric Emergency Department[NCT02521415]Phase 287 participants (Actual)Interventional2015-12-31Completed
Can Fentanyl Lead to Opioid-induced Hyperalgesia in Healthy Volunteers? A Prospective, Randomized, Double-blinded Crossover Study[NCT02252458]21 participants (Actual)Interventional2014-08-31Completed
A Randomized Trial of Intranasal Fentanyl Versus Placebo as an Adjunct to Lidocaine Infiltration in Adults Undergoing Abscess Incision and Drainage in the Emergency[NCT03872700]Phase 349 participants (Actual)Interventional2019-08-01Completed
A Prospective Study Comparing the Efficacy and Safety of 100 mcg and 200 mcg of Intranasal Fentanyl Pectin Spray as an Analgesic in Adult Males Undergoing Outpatient Cystoscopic Procedures[NCT01756651]Phase 120 participants (Actual)Interventional2013-02-28Completed
Improving Labour Induction Analgesia: a Randomized Control Trial of Single Epidural Fentanyl Bolus at Epidural Initiation for Induction of Labour[NCT04011098]Phase 15 participants (Actual)Interventional2019-07-01Terminated (stopped due to Unable to meet recruitment numbers, lack of participation)
Prehospital Analgesia With Intra-Nasal Ketamine[NCT02753114]Phase 4120 participants (Actual)Interventional2017-11-06Completed
Comparison of Sub-dissociative Dose Intranasal Ketamine to Intranasal Fentanyl for Treatment of Moderate to Severe Pain in Pediatric Patients Presenting to the Emergency Department: a Prospective, Randomized, Double-blind Study[NCT02388321]Phase 422 participants (Actual)Interventional2015-05-01Terminated (stopped due to Patients meeting inclusion criteria was low, and PI went to another institution.)
Intrathecal Magnesium Associated to Lidocaine Decreases the Incidence of the Transitory Neurologic Syndrome Following Same-day-surgery[NCT01794247]Phase 321 participants (Actual)Interventional2013-04-30Terminated (stopped due to low recruitment rate)
Methylnaltrexone for the Reversal of Opiate-Induced Constipation in the Intensive Care Unit[NCT01050595]Phase 380 participants (Anticipated)Interventional2009-12-31Recruiting
The Use of Oral Naloxone to Prevent Post Spinal Fusion Ileus[NCT03176316]Phase 4150 participants (Anticipated)Interventional2018-01-02Recruiting
Comparing Pain Relief in Early Labor: Nitrous Oxide Versus Butorphonol Study[NCT01636999]0 participants (Actual)Interventional2012-09-30Withdrawn
Efficacy of Injectable Fentanyl in Sublingual Route Versus Oral Morphine Syrup for Breakthrough Pain in Gynecologic Cancer Patients With Chronic Cancer Pain : A Randomized Double Blind Controlled Trial[NCT05037539]Phase 1/Phase 220 participants (Actual)Interventional2021-06-15Completed
A Randomized, Double Blind, Placebo Controlled Evaluation of Modafinil vs Placebo for the Treatment of General Anesthesia Related Delayed Emergence in Patients With the Diagnosis of Obstructive Sleep Apnea[NCT02494102]Phase 4105 participants (Actual)Interventional2016-02-29Terminated
An Open Label, Comparative, Randomised, Balanced Crossover Trial Comparing Nasal Fentanyl and Oral Transmucosal Fentanyl (Actiq®) in Breakthrough Pain in Patients With Cancer[NCT00496392]Phase 3115 participants (Anticipated)Interventional2007-01-31Completed
A Double-Blind, Randomized, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of EN3267 for the Treatment of Breakthrough Pain in Opioid Tolerant Cancer Patients.[NCT00262678]Phase 30 participants Interventional2005-12-31Completed
An Observational Study to Assess the Efficacy, Safety, and Tolerability of Abstral Oral Disintegrating Tablet (ODT) for the Management of Breakthrough Cancer Pain in Korean Cancer Patients[NCT03895762]143 participants (Actual)Observational2017-07-04Completed
Evaluating Pain Outcomes of Caudal vs Ilioinguinal Nerve Block in Children Undergoing Hernia Repair[NCT03041948]88 participants (Anticipated)Interventional2015-09-01Recruiting
Evaluating Pain Outcomes of Caudal vs Ilioinguinal Nerve Block in Children Undergoing Orchiopexy Repair[NCT03041935]90 participants (Actual)Interventional2015-09-01Completed
Use of Binaural Beat Premedication Reduces Post-operative Morphine Consumption in Elderly Patient Submitted to Knee Surgery[NCT02712749]40 participants (Actual)Interventional2016-09-01Completed
Comparison of Intubation Conditions After Induction With Propofol Associated With a Dose of Remifentanil or Sufentanil in Surgical Tooth Extraction.[NCT01910285]Phase 470 participants (Actual)Interventional2013-06-30Completed
Comparison of Large Antecubital Vein Versus Small Vein on Dorsum of Hand for the Prevention of Propofol Injection Pain[NCT04673500]160 participants (Actual)Interventional2013-05-31Completed
Fentanyl Buccal Soluble Films Feasible Dose Range Study for Breakthrough Pain in Taiwanese Cancer Patients[NCT03669263]36 participants (Actual)Interventional2014-11-25Completed
Intranasal Fentanyl Versus Placebo for Catheterization During a Voiding Cystourethrogram in Children[NCT00405444]Phase 364 participants (Actual)Interventional2006-11-30Completed
Fentanyl Versus Midazolam as an Adjunct to Intrathecal Bupivacaine for Postoperative Analgesia in Children Undergoing Infraumbilical Surgery[NCT03592537]Phase 2/Phase 390 participants (Actual)Interventional2018-08-15Completed
Efficacy of an Internet-based Intervention for Dental Anxiety[NCT03680755]Phase 2450 participants (Anticipated)Interventional2019-07-24Active, not recruiting
[NCT02039453]160 participants (Anticipated)Interventional2013-09-30Recruiting
Comparing Time to Readiness for Discharge After Colonoscopy: Propofol and Dexmedetomidine vs Propofol Only Sedation[NCT03139279]Phase 4122 participants (Actual)Interventional2017-05-05Completed
Midazolam With Meperidine and Dexmedetomidine vs Midazolam With Meperidine for Sedation During ERCP[NCT01404689]Phase 4110 participants (Actual)Interventional2011-08-31Completed
Dexmedetomidine Compared to Midazolam for Symptom Control in Advanced Cancer Patients: A Pilot Randomized Controlled Trial (RCT)[NCT01687751]Phase 20 participants (Actual)Interventional2012-11-30Withdrawn (stopped due to Study design determined to be not likely feasible)
A Multiple-Dose, Non-Randomized, Open-Label, Multicenter Study to Evaluate the Long-Term Safety and Effectiveness of EN3267 in the Treatment of Breakthrough Pain in Cancer Patients[NCT00263575]Phase 3139 participants (Actual)Interventional2005-12-31Completed
Survey of Knowledge and Attitude of Pain in Anesthesia Residents of Thailand[NCT05369923]140 participants (Anticipated)Observational2022-10-01Not yet recruiting
Efficacy and Adverse Events of Morphine and Fentanyl in an Aeromedical Setting[NCT00580489]204 participants (Actual)Interventional2006-08-31Completed
Goal Directed Propofol Sedation With Magnesium Sulphate Versus Dexmedetomidine for ERCP Procedure[NCT02684019]Phase 360 participants (Actual)Interventional2016-01-31Completed
Smart Pain Assesment Tool Based on Internet of Things[NCT03061240]58 participants (Actual)Interventional2017-11-20Completed
Music Therapy in Procedural Sedation in the Emergency Department[NCT02676206]60 participants (Actual)Interventional2016-02-29Completed
A Randomized, Double-blind, Placebo-controlled Multi-center Study to Evaluate the Safety and Efficacy of Fentanyl Sublingual Spray (Fentanyl SL Spray) for the Treatment of Breakthrough Cancer Pain[NCT00538850]Phase 3130 participants (Actual)Interventional2007-10-31Completed
Intranasal Fentanyl Versus Intravenous Morphine in the Emergency Department Treatment of Severe Painful Sickle Cell Crises in Children[NCT03682211]Phase 431 participants (Actual)Interventional2012-12-12Completed
Total XV - Total Therapy Study XV for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia[NCT00137111]Phase 3501 participants (Actual)Interventional2000-07-08Completed
Comparing Warm Versus Cool Temperature Water During Colonoscopy[NCT01322724]175 participants (Actual)Interventional2011-06-30Completed
Effect of High-dose Target-controlled Naloxone Infusion on Pain and Hyperal-gesia in Patients Following Recovery From Impacted Mandibular Third Molar Extraction. A Randomized, Placebo-controlled, Double-blind Crossover Study.[NCT02976337]Phase 214 participants (Anticipated)Interventional2017-10-12Recruiting
The Role of Endogenous Opioids in Mindfulness-based Chronic Pain Relief[NCT04034004]Early Phase 188 participants (Actual)Interventional2021-01-01Completed
Impact of Totally Transdermal Sedation in the Weaning From Remifentanil Infusion Among Critically Ill Patients Undergoing Mechanical Ventilation: a Pilot Randomized-controlled Study (The TOES Trial)[NCT04204967]Phase 224 participants (Anticipated)Interventional2021-02-15Recruiting
Comparison of Two Different Distraction Methods Affecting the Level of Pain and Anxiety During Extracorporeal Shock Wave Lithotripsy[NCT02725281]120 participants (Actual)Interventional2014-04-30Completed
A Randomized Controlled Trial to Evaluate the Effects of Music Therapy on Breastfeeding Rates Among Mothers of Premature Newborns[NCT00930761]101 participants (Actual)Interventional2004-03-31Completed
Magnesium Oral Supplementation to Reduce Pain in Patients With Severe Peripheral Arterial Occlusive Disease: The MAG-PAPER Randomized Clinical Trial[NCT02455726]150 participants (Anticipated)Interventional2015-09-30Not yet recruiting
Ilioinguinal/Iliohypogastric vs. Quadratus Lumborum Nerve Blockade for Elective Open Inguinal Herniorrhaphy[NCT03007966]Phase 260 participants (Actual)Interventional2017-01-30Completed
Randomized Trial Comparing Anchorsure® Suture Anchoring System and the CapioTM Slim Suture Capturing Device for Sacrospinous Ligament Suspension.[NCT03565640]48 participants (Actual)Interventional2018-10-29Completed
Evaluation of Ultrasound-Guided Adductor Canal Blockade for Postoperative Analgesia Following Robotic Medial Unicompartmental Knee Replacement[NCT01818531]Phase 4150 participants (Actual)Interventional2013-04-30Completed
Combined Spinal Epidural Analgesia in Labour: A Comparison of Two Intrathecal Regimens of Single Shot Spinal[NCT03117595]Phase 4100 participants (Actual)Interventional2017-11-23Completed
Comparative Study Between Intravenous Nalbuphine Versus Intravenous Dexmedetomidine for Conscious Sedation in Patients Undergoing Colonoscopy[NCT05689242]Phase 466 participants (Anticipated)Interventional2023-03-31Not yet recruiting
Topical Analgesia Before Inhalational Anaesthesia: A Retrospective Observational Study[NCT04959409]500 participants (Actual)Observational2020-08-01Completed
Midazolam as an Adjuvant to Bupivacaine in Quadratus Lumborum Block After Caesarean Section; Does it Offer Better Pain Control? a Randomized Double Blind Clinical Trial[NCT05261672]60 participants (Anticipated)Interventional2022-03-15Recruiting
Open-Label Study To Assess The Effect On Pain Control Of Durogesic (Fentanyl Transdermic Therapeutic System) Treatment In Subjects With Rheumatoid Arthritis Or Osteoarthritis Of The Knee Or Hip.[NCT00524160]Phase 4264 participants (Actual)Interventional2001-07-31Completed
A Randomized Trial of the Impact of Three Labor Analgesia Techniques on Labor Duration in Spontaneously Laboring Nulliparous Parturients[NCT01982838]129 participants (Actual)Interventional2010-07-31Terminated (stopped due to Low qualified candidate enrollment)
A Randomized Trial of the Impact of Three Labor Analgesia Techniques on Labor Duration in Nulliparous Labor Inductions[NCT01982851]134 participants (Actual)Interventional2010-07-31Terminated (stopped due to low qualified candidate enrollment)
A Retrospective Case-controlled Study of the Association Between Request to Discontinue Second Stage Labor Epidural Analgesia and Risk of Instrumental Vaginal Delivery[NCT00443560]2,162 participants (Actual)Observational2006-01-31Completed
Comparison of Programmed Intermittent Epidural Boluses With Continuous Epidural Infusion for Maintenance of Labor Analgesia[NCT02949271]Phase 4179 participants (Actual)Interventional2016-11-08Completed
Early Compared With Late Neuraxial Analgesia in Nulliparous Labor Induction[NCT00380978]1,026 participants (Actual)Interventional2001-10-31Completed
Intravenous Sedation and Analgesia Using Propofol, Fentanyl and Ketamine (PFK) Versus General Anesthesia in Minor Urological Procedures.[NCT04285528]200 participants (Actual)Interventional2019-04-17Completed
Switching From Morphine to Oral Methadone Plus Acetaminophen in the Treatment of Cancer Pain: A Randomized, Double-Blind Study[NCT00525967]Phase 2/Phase 350 participants (Anticipated)Interventional2006-02-28Recruiting
Pericapsular Nerve Group Block Versus Fascia Iliaca Block for Pre- and Post-Operative Analgesia in Elderly Patients With Hip Fracture[NCT04564326]51 participants (Anticipated)Interventional2021-01-01Not yet recruiting
Efficacy of Alfentanyl Versus Sufentanyl in Children for Pain During Treatment by Tracheal Suction in an Intensive Care Unit.[NCT01235637]Phase 340 participants (Actual)Interventional2010-06-30Completed
Prospective Longitudinal Observational Study to Evaluate the Clinical Characteristics and Opioids Treatments in Patients With Breakthrough Cancer Pain[NCT01946555]150 participants (Actual)Observational2013-09-30Completed
Comparison of Sub-dissociative Intranasal Ketamine Plus Standard Pain Therapy Versus Standard Pain Therapy in the Treatment of Pediatric Sickle Cell Disease Vasoocclusive Crises in Resource-limited Settings: a Multi-centered, Randomized, Controlled Trial[NCT02573714]160 participants (Anticipated)Interventional2015-12-31Recruiting
IN Dexmedetomidine for Procedural Sedation in Pediatric Closed Reductions for Distal Forearm Fractures. Timmons Z MD, Feudale B MD Children Presenting to the ED With Distal Forearm Extremity Fractures Often Require Re-alignment Under Conscious Sedation. T[NCT03466242]Early Phase 140 participants (Anticipated)Interventional2018-05-01Not yet recruiting
Effects of Lavender Aromatherapy and Cold Application on Pain During Drain Removal[NCT04798040]121 participants (Actual)Interventional2021-09-01Completed
Evaluating Specific and Non-Specific Mechanisms in Two Distinct Complementary/Integrative Interventions for Chronic Pain[NCT04744883]Early Phase 1240 participants (Anticipated)Interventional2020-08-10Recruiting
Randomized Controlled Trial of the Use of Intramuscular Fentanyl for the Incision and Drainage of Abscess in the Emergency Department[NCT01881997]Phase 40 participants (Actual)Interventional2011-06-30Withdrawn (stopped due to IRB modifications made study impractical.)
Ketofol Versus Fentofol for Procedural Sedation of Children 3 to 17 Years Old: a Double-Blind Randomized Controlled Trial[NCT02079090]Phase 330 participants (Actual)Interventional2014-07-31Completed
A Phase I Clinical Study Evaluating the Safety, Tolerability and Pharmacokinetics of HSK21542 in Healthy Volunteers[NCT04213196]Phase 166 participants (Actual)Interventional2020-01-09Completed
Comparison of Remifentanil and Dexmedetomidine for Monitored Anaesthesia Care[NCT02476981]75 participants (Actual)Interventional2012-08-31Completed
A Randomised Control Trial to Determine Whether Intervention Based on a Microstream Capnography-based Ventilation Monitoring System Will Decrease Hypoxaemaia During Intravenous Sedation With Midazolam.[NCT01949012]190 participants (Actual)Interventional2013-10-31Completed
Tetracaine (Ametop®) Compared to Placebo for Reducing Pain Associated With Intramuscular Injection of Palivizumab (Synagis®) - A Pilot Study[NCT00484393]Phase 47 participants (Actual)Interventional2007-11-30Completed
Distraction in the Emergency Using Virtual Reality for Intravenous Needs in Children to Improve Comfort (DEVINCI): A Pilot Randomized Controlled Trial[NCT03750578]62 participants (Actual)Interventional2018-12-17Completed
Morphine or Fentanyl for Refractory Dyspnea in COPD[NCT03834363]Phase 460 participants (Anticipated)Interventional2019-11-15Recruiting
Stress Assessment in Preterm Infants With Respiratory Distress Syndrome Treated or Not With an Analgesic Drug During the Traditional or the Less Invasive Method of Surfactant Therapy.[NCT04073173]Phase 480 participants (Anticipated)Interventional2020-11-01Not yet recruiting
Optimal Lidocaine Propofol Mixture for Painless Induction of Anesthesia[NCT05898061]100 participants (Anticipated)Observational [Patient Registry]2023-03-01Recruiting
Ketamine Versus Etomidate for Procedural Sedation for Pediatric Orthopedic Reductions[NCT00596050]Phase 450 participants (Actual)Interventional2006-08-31Completed
Systemic Absorption of Lidocaine After Ultrasound Guided Hematoma Block for Reduction of Different Types of Pediatric Distal Radius Fractures[NCT04359017]Phase 40 participants (Actual)Interventional2020-11-01Withdrawn (stopped due to Sponsoring staff have left institution)
Erector Spinae Plane Block for Postoperative Analgesia in Laparoscopic Cholecystectomy, Is It a Promising Alternative Modality?[NCT05158270]90 participants (Anticipated)Interventional2021-11-15Recruiting
Study of the Efficiency of the Ketamine With Low Analgesic Doses, in Association With High Opioids, in the Treatment of the Rebels Pains, in Palliative Phase of the Cancerous Disease[NCT01326325]Phase 324 participants (Actual)Interventional2011-07-31Completed
Effects of Chronic Musculoskeletal Pain and Opioidergic Versus Placebo Interventions on Neuroendocrine Function in Men[NCT00737737]Phase 48 participants (Actual)Interventional2008-08-31Completed
Postoperative Ibuprofen Use and Risk of Bleeding in Pediatric Tonsillectomy[NCT03385057]Phase 10 participants (Actual)Interventional2018-09-30Withdrawn (stopped due to Study design flaws; research design needed to be reconfigured)
A Study to Assess the Safety, Efficacy and Pharmacokinetics of Durogesic (Fentanyl Transdermal Drug Delivery System) in the Treatment of Pediatric Patients With Chronic Pain Requiring Long-term Opioid Therapy[NCT00271453]Phase 341 participants (Actual)Interventional1996-02-29Completed
Pain Control for Intrauterine Device Placement: A Randomized Controlled Trial of Paracervical Block[NCT02219308]67 participants (Actual)Interventional2014-10-31Completed
An Evaluation of the Paracervical Block for Pain Control in First Trimester Surgical Abortion[NCT01094366]Phase 4121 participants (Actual)Interventional2010-04-30Completed
Pain Measurement in Healthy Volunteers[NCT00001597]40 participants Observational1997-03-31Completed
Comparative Study of Magnesium Sulfate Versus Fentanyl as Adjuvants to Bupivacaine for Thoracic Epidural Analgesia in Multiple Traumatic Fracture Ribs[NCT03595397]60 participants (Anticipated)Interventional2018-07-31Not yet recruiting
Non- Inferiority Study of Erector Spinae Plane Block Compared to Thoracic Epidural Analgesia in Multimodal Pain Management of Multiple Rib Fractures[NCT05069961]0 participants (Actual)Interventional2023-05-31Withdrawn (stopped due to Study was closed with IRB as PI wants to design the protocol extensively.)
The Effect of Different Applications of Tourniquet on Total Knee Arthroplasty[NCT03256058]60 participants (Anticipated)Interventional2017-08-20Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants Administered Additional Pain Medications

After the procedure, research personnel will ask anesthetist what medications, if any, they gave outside of the study protocol (NCT04871425)
Timeframe: Immediately postoperatively

InterventionParticipants (Count of Participants)
Ketamine23
Fentanyl30

Provider Satisfaction With Anesthesia Assessed by the VAS

After the procedure, research personnel will assess provider's satisfaction with patient's anesthesia on a 100mm visual analog scale. The minimum score is 0mm and the maximum score if 100mm, with higher scores indicating higher satisfaction. (NCT04871425)
Timeframe: Immediately postoperatively

Interventionscore on a scale (Mean)
Ketamine90
Fentanyl86.8

Satisfaction With Anesthesia Assessed by the ISAS

After the procedure, either at time of discharge (if less than 30 minutes) or at 30 minutes (if not yet discharged), research personnel will assess the participant's satisfaction with anesthesia using the Iowa Satisfaction with Anesthesia Scale. This is a validated perioperative anesthesia satisfaction scale with a minimum score of -3 and a maximum score of +3 with higher scores indicating higher satisfaction. (NCT04871425)
Timeframe: At discharge or 30 minutes after the procedure

Interventionscore on a scale (Mean)
Ketamine2.4
Fentanyl2.2

Postoperative Pain Assessed by the VAS

Patients will complete 2 followup surveys asking about their postoperative pain after discharge. This will be assessed on a 100mm visual analog scale. The minimum score is 0mm and the maximum score if 100mm, with higher scores indicating higher pain levels. (NCT04871425)
Timeframe: 24 hours postoperatively and 7 days postoperatively

,
Interventionscore on a scale (Mean)
Pain post-op day 1Pain post-op day 7
Fentanyl2219.1
Ketamine24.518.2

Satisfaction With Anesthesia (Iowa Satisfaction With Anesthesia Scale [ISAS])

The Iowa Satisfaction with Anesthesia Scale (ISAS) was given to women following a surgical abortion. The ISAS score is the mean of 11 responses to questions regarding satisfaction with anesthesia and has a score range of -3 (disagree strongly) to 3 (agree strongly). (NCT02755090)
Timeframe: Assessed 30 minutes after procedure completion.

Interventionunits on a scale (Mean)
Nitrous Oxide and IV Saline0.7
Standard Care Group (IV Sedation and Oxygen)1.8

Visual Analog Scale (VAS) Score for Maximum Procedural Pain

To compare women's maximum procedural pain measured on a visual analog scale (VAS) during a surgical abortion between 12 weeks 0 days to 16 weeks 0 days gestational age between women randomized to nitrous oxide versus intravenous sedation. A score of 0 represents no pain and a score of 100 represents pain as bad as it could be. (NCT02755090)
Timeframe: Assessed immediately following completion of the procedure (as defined as removal of the speculum)

Interventionunits on a scale (Mean)
Nitrous Oxide and IV Saline54.1
Standard Care Group (IV Sedation and Oxygen)34.0

Capnometry Value

(NCT02778880)
Timeframe: 15 minutes after study medication

InterventionmmHg (Mean)
Ketamine36.6
Fentanyl38.3

Capnometry Value

(NCT02778880)
Timeframe: 30 minutes after study medication

InterventionmmHg (Mean)
Ketamine38.6
Fentanyl40.4

Capnometry Value

(NCT02778880)
Timeframe: 60 minutes after study medication

InterventionmmHg (Mean)
Ketamine38.7
Fentanyl38.9

Diastolic Blood Pressure

(NCT02778880)
Timeframe: 15 minutes after study medication

InterventionmmHg (Mean)
Ketamine76.1
Fentanyl73.4

Diastolic Blood Pressure

(NCT02778880)
Timeframe: 30 minutes after study medication

InterventionmmHg (Mean)
Ketamine76.3
Fentanyl73.6

Diastolic Blood Pressure

(NCT02778880)
Timeframe: 60 minutes after study medication

InterventionmmHg (Mean)
Ketamine70.8
Fentanyl70.6

Difference From Baseline in Visual Analog Scale Pain Score

A VAS score is a self reported pain score of 0-100 millimeters (0 = no pain; 100 = worst possible pain). A decrease in a VAS score indicates a decrease in pain severity. (NCT02778880)
Timeframe: 15 minutes after study medication

Interventionscore on a scale (Mean)
Ketamine-24.4
Fentanyl-25.3

Difference From Baseline in Visual Analog Scale Pain Score

A VAS score is a self reported pain score of 0-100 millimeters (0 = no pain; 100 = worst possible pain). A decrease in a VAS score indicates a decrease in pain severity. (NCT02778880)
Timeframe: 30 minutes after study medication

Interventionscore on a scale (Mean)
Ketamine-30.6
Fentanyl-31.9

Difference From Baseline in Visual Analog Scale Pain Score

A VAS score is a self reported pain score of 0-100 millimeters (0 = no pain; 100 = worst possible pain). A decrease in a VAS score indicates a decrease in pain severity. (NCT02778880)
Timeframe: 60 minutes after study medication

Interventionscore on a scale (Mean)
Ketamine-27.7
Fentanyl-29.0

Heart Rate

(NCT02778880)
Timeframe: 15 minutes after study medication

Interventionbeats per minute (Mean)
Ketamine90.1
Fentanyl84.4

Heart Rate

(NCT02778880)
Timeframe: 30 minutes after study medication

Interventionbeats per minute (Mean)
Ketamine90.5
Fentanyl85.6

Heart Rate

(NCT02778880)
Timeframe: 60 minutes after study medication

Interventionbeats per minute (Mean)
Ketamine85.1
Fentanyl82.9

Oxygen Saturation

(NCT02778880)
Timeframe: 15 minutes after study medication

Interventionpercent (Mean)
Ketamine99.6
Fentanyl99.2

Oxygen Saturation

(NCT02778880)
Timeframe: 30 minutes after study medication

Interventionpercent (Mean)
Ketamine99.5
Fentanyl99.4

Oxygen Saturation

(NCT02778880)
Timeframe: 60 minutes after study medication

Interventionpercent (Mean)
Ketamine99.3
Fentanyl99.3

Respiratory Rate

(NCT02778880)
Timeframe: 15 minutes after study medication

Interventionbreaths per minute (Mean)
Ketamine23.1
Fentanyl22.3

Respiratory Rate

(NCT02778880)
Timeframe: 30 minutes after study medication

Interventionbreaths per minute (Mean)
Ketamine23.3
Fentanyl19.9

Respiratory Rate

(NCT02778880)
Timeframe: 60 minutes after study medication

Interventionbreaths per minute (Mean)
Ketamine21.8
Fentanyl19.7

Systolic Blood Pressure

(NCT02778880)
Timeframe: 15 minutes after study medication

InterventionmmHg (Mean)
Ketamine127.3
Fentanyl127.9

Systolic Blood Pressure

(NCT02778880)
Timeframe: 30 minutes after study medication

InterventionmmHg (Mean)
Ketamine126.3
Fentanyl123.4

Systolic Blood Pressure

(NCT02778880)
Timeframe: 60 minutes after study medication

InterventionmmHg (Mean)
Ketamine122.3
Fentanyl122.0

Exploratory Outcome: Reduction in Age Appropriate Pain Scale Scores

Mean difference in the reduction of the pain scale scores at 20 minutes. Two commonly used, age appropriate and previously validated, pediatric pain assessment tools were used: FACES Pain Scale - Revised for children ages 4-10 and the Visual Analog Scale for children ages 11-17. The FACES Pain Scale - Revised is a self-reported measure of pain intensity developed for children with pain intensity represented by images of grimacing faces on a scale of 0 (no pain) to 10 (maximum pain). The Visual Analog Scale is a self-reported measure of pain intensity where patients mark their pain level on a 10 cm line that represents a continuum of no pain at 0 cm and worst pain at 10 cm. For analysis, pain scale data were merged and reported as values form 0 to 100. The minimum clinically significant reduction in pain was defined as a decrease of 20. (NCT02521415)
Timeframe: 20 minutes

Interventionunits on a scale (Mean)
Ketamine44
Fentanyl35

Secondary Outcome: Total Dose of Opioid Pain Medication in Morphine Equivalents/kg/Hour

Compare the total dose of opioid pain medication in morphine equivalents/kg/hour required during the ED evaluation of children with suspected forearm fractures after randomization and treatment with IN ketamine or IN fentanyl. (NCT02521415)
Timeframe: participants will be followed during the emergency department length of stay, estimated to average 6 hours

Interventionmorphine equivalents/kg/hr (Median)
Ketamine0.04
Fentanyl0.05

NRS Pain Score After Blunt Dissection

Patient reported NRS pain scores after Blunt Dissection. The NRS for pain is a reliable and validated measure of pain intensity ranging from 0 - no pain, to 10 - worst pain imaginable. (NCT03872700)
Timeframe: Measured once anytime up to 60 minutes following intranasal administration

Interventionscore on a scale (Mean)
Intranasal Fentanyl4.1
Placebo4.4

NRS Pain Score After Irrigation

Patient reported NRS pain scores after Irrigation. The NRS for pain is a reliable and validated measure of pain intensity ranging from 0 - no pain, to 10 - worst pain imaginable. (NCT03872700)
Timeframe: Measured once anytime up to 60 minutes following intranasal administration

Interventionscore on a scale (Mean)
Intranasal Fentanyl3.4
Placebo2.6

NRS Pain Score After Lidocaine Injection

Patient reported NRS pain scores after Lidocaine injection. The NRS for pain is a reliable and validated measure of pain intensity ranging from 0 - no pain, to 10 - worst pain imaginable. (NCT03872700)
Timeframe: Following Lidocaine injection measured once anytime up to 12 minutes after intranasal administration

Interventionscore on a scale (Mean)
Intranasal Fentanyl8.4
Placebo8.0

NRS Pain Score After Packing of Abscess

Patient reported pain after Packing of abscess. The NRS for pain is a reliable and validated measure of pain intensity ranging from 0 - no pain, to 10 - worst pain imaginable. (NCT03872700)
Timeframe: Measured once at the time of completion of application of the bandage, up to 60 minutes following intranasal administration

Interventionscore on a scale (Mean)
Intranasal Fentanyl4.5
Placebo3.9

NRS Pain Score Following Incision

Patient reported NRS pain scores following Incision. The NRS for pain is a reliable and validated measure of pain intensity ranging from 0 - no pain, to 10 - worst pain imaginable. (NCT03872700)
Timeframe: Measured once anytime up to 60 minutes following intranasal administration

Interventionscore on a scale (Mean)
Intranasal Fentanyl3.9
Placebo3.9

Numerical Rating Scale (NRS) Pain Score at Baseline

Patient reported pain scores at baseline. The NRS for pain is a reliable and validated measure of pain intensity ranging from 0 - no pain, to 10 - worst pain imaginable. (NCT03872700)
Timeframe: Baseline

Interventionscore on a scale (Mean)
Intranasal Fentanyl8.3
Placebo8.1

Numerical Rating Scale (NRS) Pain Score for Overall Procedure

Patient reported pain scores for overall Procedure assessed immediately after placement of dressing at the end of procedure. The NRS for pain is a reliable and validated measure of pain intensity ranging from 0 - no pain, to 10 - worst pain imaginable. (NCT03872700)
Timeframe: Measured once following placement of dressing at completion of procedure, up to 60 minutes following intranasal administration

Interventionscore on a scale (Mean)
Intranasal Fentanyl6.2
Placebo7.0

Adverse Events at 30 Minutes

The patient were asked at 30 minutes post administration of analgesia if they experienced any side effects like nausea, vomiting, headache etc. (NCT02388321)
Timeframe: 30 minutes

InterventionParticipants (Count of Participants)
Ketamine0
Fentanyl0

Pain Score at 30 Minutes

An 11 point Likert Visual Analog Scale with 0 being no pain, 5 being moderate pain and 10 being very severe pain was verbally administered to the patient at 30 minutes post administration of analgesia. (NCT02388321)
Timeframe: 30 minutes

Interventionunits on a scale (Mean)
Ketamine3.36
Fentanyl2.09

Length of Time From Extubation to Discharge From Postanesthesia Recovery Unit

Length of time of above compared between groups (NCT02494102)
Timeframe: 24 hours

Interventionminutes (Mean)
Placebo53.5
Modafinil61.0

Postanesthesia Quality Recovery Scale Score

Postanesthesia quality recovery scale (PQRS). Component and aggregate scoring on the scale. Measures physiology, nociceptive, emotional activities of daily living cognitive and overall patient perspective. The scale is dimensionless and the aggregate of all individually tested dimensions is scaled from 17-65. A higher value implies improved postanesthesia recovery. Mean difference was assessed in each patient and aggregated thus patients with no difference between pre- and post-operative scores were zeroed (received a zero score if the difference was zero). A negative value was associated with worse outcome. (NCT02494102)
Timeframe: baseline and 6 hours after surgery

Interventionunits on a scale (Mean)
Placebo-5.67
Modafinil-8.91

Average Total Propofol Consumption Per Group

Total propofol consumption per subject was measured as μg/kg/min of procedure in minutes. The average propofol consumption in each group will be measured as secondary outcome. (NCT03139279)
Timeframe: between 7 and 57 minutes (median 19 min)

Interventionμg/kg/min (Median)
Dexmedetomidine and Propofol140
Saline Placebo and Propofol180

Lowest Intraoperative % Change in MAP From Baseline

Lowest intraoperative percent (%) change in mean arterial pressure (MAP) from baseline (average in each group) (NCT03139279)
Timeframe: 30 minutes

Interventionpercentage change (Mean)
Dexmedetomidine and Propofol30
Saline Placebo and Propofol21

Number of Participants With Apneic Episodes Intraoperatively Requiring Positive Pressure Ventilation

Incidence of apneic episodes intraoperatively requiring positive pressure ventilation in each group (NCT03139279)
Timeframe: 30 minutes

InterventionParticipants (Count of Participants)
Dexmedetomidine and Propofol0
Saline Placebo and Propofol0

Percentage of Subjects Ready for Discharge in Each Group at 30 Minutes Post Procedure

Each subject was assessed for readiness for discharge at 10, 20 and 30 minutes after the procedure, using the Modified Post-Anesthesia Discharge Scoring System (MPADSS). A subject getting an MPADS score of 9-10 is deemed ready for discharge. The percentage of subjects ready for discharge in each group at 10, 20 and 30 minutes will be measured as primary outcome. (NCT03139279)
Timeframe: 30 minutes

InterventionParticipants (Count of Participants)
Dexmedetomidine and Propofol26
Saline Placebo and Propofol44

Evaluate the Long-term Safety and Effectiveness of EN3267

(NCT00263575)
Timeframe: screening, 2 week titration period and 12 monthly study visits

,,
Interventionparticipants (Number)
Patients with at least 1 AEPatients with at least 1 AE causing discontinuePatients with at least 1 SAEPatients with an AE resulting in death
Maintenance87234015
Overall116374619
Titration641474

Mean Change in Numeric Pain Score (NPS) From First to Last Dose

"Mean difference in the numeric pain score (NPS) from the first dose to the final dose of medication administered.~A significant mean pain score change is defined as greater than or equal to 2~Numeric Pain Score (NPS) 0-10, 0 Least pain, 10 most pain" (NCT00580489)
Timeframe: Medication was administered over a mean transport time of 37 minutes in the Morphine group and 43 minutes in the Fentanyl group.

Interventionscore on a scale (Mean)
Morphine2.2
Fentanyl2.5

Recording of Instance of Narcotic Side Effects.

Instances of narcotic side effects (vital sign derangement, itching, nausea/vomiting) . (NCT00580489)
Timeframe: Groups were observed a mean of 37 minutes in the Morphine Group and a mean of 43 minutes in the Fentanyl group for side effects.

Interventionparticipants (Number)
Arm C Morphine0
Arm D Fentanyl0

Summed Pain Intensity Differences (SPID) at 30 Minutes After Dosing (SPID30)

"Pain intensity was assessed by the participant using a 0-100 mm visual analog scale where 0 represented no pain and 100 represented worst possible pain at 0 (baseline, beginning of the pain episode), 5, 10, 15, and 30 minutes after each dose of study medication during each breakthrough pain episode. The pain intensity difference was defined as the difference in pain intensity at the various time points versus time 0 (baseline). SPID30 was calculated as the time-weighted sum of the PID scores using the following formula: SPID30=(5*PID5)+(5*PID10)+(5*PID15)+(15*PID30). The minimum and maximum SPID30 scores were -3000 and 3000. A higher score indicates less pain." (NCT00538850)
Timeframe: Baseline (time 0, beginning of each pain episode) through 30 minutes after dosing for each pain episode

InterventionUnits on a scale (Mean)
Fentanyl Sublingual Spray640.3
Placebo399.6

Global Evaluation of the Study Medication at 30 and 60 Minutes After Dosing

Global evaluation of the study medication was assessed by the participant on a 5-point scale (1=Poor, 2=Fair, 3=Good, 4=Very good, 5=Excellent) at 30 and 60 minutes after each dose of study medication during each breakthrough pain episode. A higher score indicates a better evaluation. (NCT00538850)
Timeframe: 30 through 60 minutes after dosing for each pain episode

,
InterventionUnits on a scale (Mean)
30 minutes60 minutes
Fentanyl Sublingual Spray2.83.1
Placebo2.02.2

Summed Pain Intensity Differences (SPID) at 5, 10, 15, 45, and 60 Minutes After Dosing

"Pain intensity was assessed by the participant using a 0-100 mm visual analog scale where 0 represented no pain and 100 represented worst possible pain at 0 (baseline, beginning of the pain episode), 5, 10, 15, 30, 45 and 60 minutes after each dose of study medication during each breakthrough pain episode. The pain intensity difference was defined as the difference in pain intensity at the various time points versus time 0 (baseline). SPID was calculated as the time-weighted sum of the PID scores using the following formulas: SPID5=(5*PID5), SPID10=(5*PID5)+(5*PID10), SPID15=(5*PID5)+(5*PID10)+(5*PID15), SPID30=(5*PID5)+(5*PID10)+(5*PID15)+(15*PID30), SPID45=(5*PID5)+(5*PID10)+(5*PID15)+(15*PID30)+(15*PID45), SPID60=(5*PID5)+(5*PID10)+(5*PID15)+(15*PID30) +(15*PID45) +(15*PID60). The minimum and maximum SPID scores were -500 to 500, -1000 to 1000, -1500 to 1500, -3000 to 3000, -4500 to 4500, and -6000 to 6000, respectively. A higher score indicates less pain." (NCT00538850)
Timeframe: Baseline (time 0, beginning of each pain episode) through 60 minutes after dosing for each pain episode

,
InterventionUnits on a scale (Mean)
SPID5SPID10SPID15SPID45SPID60
Fentanyl Sublingual Spray40.3115.0220.61122.01649.0
Placebo32.081.1150.3667.0965.7

Total Pain Relief (TOTPAR) at 5, 10, 15, 30, 45, and 60 Minutes After Dosing

Pain relief (PAR) was assessed by the participant on a 5-point scale (1=No relief, 2=A little relief, 3=Moderate relief, 4=A lot of relief, 5=Complete relief) at 5, 10, 15, 30, 45 and 60 minutes after each dose of study medication during each breakthrough pain episode. TOTPAR was calculated as the time-weighted sum of the PAR scores at each time point using the following formulas: TOTPAR5=(5*PAR5), TOTPAR10=(5*PAR5)+(5*PAR10), TOTPAR15=(5*PAR5)+(5*PAR10)+(5*PAR15), TOTPAR30=(5*PAR5)+(5*PAR10)+(5*PAR15)+(15*PAR30), TOTPAR45=(5*PAR5)+(5*PAR10)+(5*PAR15)+(15*PAR30)+(15*PAR45), TOTPAR60=(5*PAR5)+(5*PAR10)+(5*PAR15)+(15*PAR30) +(15*PAR45) +(15*PAR60). The minimum and maximum TOTPAR5, TOTPAR10, TOTPAR15, TOTPAR30, TOTPAR45, and TOTPAR60 scores were 5 to 25, 10 to 50, 15 to 75, 30 to 150, 45 to 225, and 60 to 300, respectively. A higher score indicates more pain relief. (NCT00538850)
Timeframe: 5 through 60 minutes after dosing for each pain episode

,
InterventionUnits on a scale (Mean)
TOTPAR5TOTPAR10TOTPAR15TOTPAR30TOTPAR45TOTPAR60
Fentanyl Sublingual Spray8.619.732.978.3126.3176.4
Placebo7.616.727.161.095.5131.2

Circulating Leukemia Cells in Peripheral Blood Change From Prior to the Methotrexate Infusion to Three Days After Between Two Arms (4 Hours vs. 24 Hours)

"White blood cell (leukocytes) counts in peripheral blood by Complete Blood Count~Measurement: Percentage change of leukemia cells from baseline" (NCT00137111)
Timeframe: Immediately before the methotrexate infusion and three days after subsequent infusion

InterventionPercent change (Mean)
4 hr-44
24 hr-50

Continuous Complete Remission Since Week 56 Therapy.

CCR was measured from end of week 56 therapy to the date of first treatment failure of any kind (relapse, death, lineage switch, or second malignancy) or to the last date of follow-up. Measurement was determined by Kaplan-Meyer estimate. (NCT00137111)
Timeframe: Median follow up time (range) 4.5 (1 to 7.8) years

InterventionPercentage of participants (Number)
Patients With High Risk of CNS Relapse92.2

Mean Difference of Active Methotrexate Polyglutamates (MTXPG) in Leukemia Cells Between Two Arms (4 Hours vs. 24 Hours).

Children were randomly assigned to receive initial single-agent treatment with HDMTX (1g/m^2) as either a 24-hour infusion or a 4-hour infusion and the outcome measure was the accumulation of MTXPG in leukemia cells. (NCT00137111)
Timeframe: 42 hours after start of high dose methotrexate infusion (HDMTX)

Interventionpmol/1,000,000,000 cells (Mean)
4 hr1688
24 hr2521

Overall Event-free Survival (EFS)

EFS was measured from the start of on-study to the date of first treatment failure of any kind (relapse, death, lineage switch, or second malignancy) or to the last date of follow-up. Failure to enter remission was considered an event at time zero. Measurement was determined by Kaplan-Meyer estimate. (NCT00137111)
Timeframe: Median follow-up time (range) 5.6 (1.3 to 8.9) years

InterventionPercentage of Participants (Number)
Total Therapy87.3

Median Difference in CASP1 Gene Expression in Primary Leukemia Cells of Patients in Glucocorticoid-resistant Cells vs Glucocorticoid-sensitive Cells

Prednisolone sensitivity was measured in primary leukemia cells from bone marrow collected at diagnosis. Expression of CASP1 was determined by HG-U133A microarray. Values given are gene expression values, and the unit is arbitrary units (AU) defined as scaled fluorescence measured on microarray. (NCT00137111)
Timeframe: Pre-treatment

Interventionarbitrary units (Median)
Prednisolone-sensitive cellsPrednisolone-resistant cells
Total Therapy341.3447.9

Median Difference in NLRP3 Gene Expression in Primary Leukemia Cells of Patients in Glucocorticoid-resistant Cells vs. Glucocorticoid-sensitive Cells

Prednisolone sensitivity was measured in primary leukemia cells from bone marrow collected at diagnosis. Expression of NLRP3 was determined by HG-U133A microarray. Values given are gene expression values, and the unit is arbitrary units (AU) defined as scaled fluorescence measured on microarray. (NCT00137111)
Timeframe: Pre-treatment

Interventionarbitrary units (Median)
Prednisolone-sensitive cellsPrednisolone-resistant cells
Total Therapy41.2110.7

Minimal Residual Disease (MRD)

Detection of MRD at end of induction where positive MRD was defined as one or more leukemic cell per 10,000 mononuclear bone-marrow cells (>=0.01%). (NCT00137111)
Timeframe: End of Induction (Day 46 MRD measurement)

Interventionparticipants (Number)
Negative <0.01%Positive >= 0.01%
Total Therapy390102

"Perceived Intervention Effectiveness Was Assessed With a VAS (0 = Not Effective at All; 10 = Most Effective Imaginable) for Each Intervention Session."

(NCT04034004)
Timeframe: Delivered after completion of each of the 4 meditation intervention sessions. Up to 8 weeks.

,
Interventionunits on a scale (Mean)
intervention 1 effectivenessintervention 2 effectivenessintervention 3 effectivenessintervention 4 effectiveness
Mindfulness Meditation4.834.054.214.51
Non-mindfulness Meditation5.135.175.215.40

Brief Pain Inventory (BPI)

Pain severity and interference: impact of pain on daily function, location of pain, pain medications and amount of pain relief in the past 24 hours or the past week. Higher scores indicate higher chronic pain. BPI severity and interference scales are used and collected before and after each intervention. Higher BPI severity indicate higher chronic pain severity. Higher BPI interference scores indicate higher chronic pain interference.The scoring scale for severity and interference range from 0 - 10, respectively. (NCT04034004)
Timeframe: Administered at the baseline, post-intervention session 6 and post-intervention session 7. Outcome measurements will compare in BPI severity and interference from baseline to session 7.

,
Interventionunits on a scale (Mean)
baseline BPI severitysession 7 BPI severitybaseline BPI interferencesession 7 BPI interference
Mindfulness Meditation4.473.944.403.38
Non-mindfulness Meditation5.225.155.174.57

Pain Catastrophizing Scale

This is a 13-item questionnaire with 3 subscales assessing rumination, magnification, and helplessness in patients. A numeric value between 0 (not at all) and 4 (all the time) is provided in response to each statement. Scores on this assessment range from 0 to 52, with higher values reflecting more salient impacts of pain on one's day to day experience. The total range is from 0 - 52. (NCT04034004)
Timeframe: The Pain Catastrophizing Scale was administered at the baseline, post-intervention session 6 and session 7. Outcome measurements will compare change in Pain Catastrophizing Scale from baseline to session 7.

,
Interventionunits on a scale (Mean)
Baseline PCSSession 7 PCS
Mindfulness Meditation18.5715.33
Non-mindfulness Meditation20.8318.48

Pain Ratings

"Numerical pain ratings (NRS) will be assessed while lying on the back and in response to the straight leg raise test (SLR). Pain ratings will be collected during SLR 1 and SLR 2 in the baseline, saline and naloxone sessions, respectively. The 11 point scan will include a minimum rating of 0 which is characterized as no pain whereas the maximum (10) is labeled as most intense imaginable. Higher numbers correspond to higher pain." (NCT04034004)
Timeframe: Pain ratings were collected while lying supine and in response to the straight leg raise test. Collected twice, once in the first half and one in the second half of the baseline, saline infusion and naloxone infusion sessions. Up to 8 weeks total.

,
Interventionunits on a scale (Mean)
baseline session: supine 1baseline session: straight leg raise test 1baseline session: supine 2baseline session: straight leg raise test 2saline session: supine 1saline session: straight leg raise test 1saline session: supine 2saline session: straight leg raise 2naloxone session: supine 1naloxone session: straight leg raise 1naloxone session: supine 2naloxone session: straight leg raise 2
Mindfulness Meditation3.604.834.135.153.234.373.903.673.304.303.733.45
Non Mindfulness Meditation4.695.414.765.784.625.754.375.324.826.105.185.52

SF-12 Health Survey (SF-12) Physical Functioning

This is a 12-item version of the SF-12 item Health Survey designed to assess general mental and physical functioning, and overall health-related quality of life. We used the physical functioning SF-12 scale and collected this information before and after each intervention and by group. The total range of scores is from 0 - 100. The minimum total score is 0 and the maximum score is 100. Higher scores indicate better functioning. (NCT04034004)
Timeframe: Up to 8 weeks. Administered at visit 1, 6 and 7. Outcome measurements will compare SF-12 health survey from baseline to session 7.

,
Interventionunits on a scale (Mean)
baseline SF physical functioningsession 7 SF physical functioning
Mindfulness Meditation52.5039.66
Non-mindfulness Meditation49.1744.83

The Roland-Morris Disability Questionnaire (RMDQ)

The Roland-Morris Questionnaire (RMDQ) is a self-administered disability measure in which greater levels of disability are reflected by higher numbers on a 24-point scale. The RMDQ has been shown to yield reliable measurements, which are valid for inferring the level of disability, and to be sensitive to change over time for groups of patients with low back pain. Higher scores indicate greater disability. Total RMDQ scores are used before and after each intervention by group. The range of scores is from 0 - 24. (NCT04034004)
Timeframe: The Roland-Morris Disability Questionnaire was administered at the baseline, post-intervention session 6 and session 7. Outcome measurements will compare RMDQ from baseline to session 7.

,
Interventionunits on a scale (Mean)
baseline RMDQsession 7 RMDQ
Mindfulness Meditation12.8612.03
Non-mindfulness Meditation13.8514.02

Maternal Breastfeeding 7-15 Days After Discharge

Maternal breastfeeding means: exclusive maternal breastfeeding, predominant maternal breastfeeding (maternal milk associated to other liquid, except formula) and continuous maternal breastfeeding (maternal milk associate to other food, including formula). (NCT00930761)
Timeframe: At the first follow-up visit (7-15 days after discharge)

Interventionparticipants (Number)
Control32
Music Therapy42

Maternal Breastfeeding at 30 Days After Discharge

Maternal breastfeeding means exclusive maternal breastfeeding, predominant maternal breastfeeding (maternal milk associated to other liquid, except formula) and continuous maternal breastfeeding (maternal milk associate to other food, including formula). (NCT00930761)
Timeframe: At 30 days after the infant hospital discharge

Interventionparticipants (Number)
Control30
Music Therapy38

Maternal Breastfeeding at 60 Days After Discharge

Maternal breastfeeding means exclusive maternal breastfeeding, predominant maternal breastfeeding (maternal milk associated to other liquid, except formula) and continuous maternal breastfeeding (maternal milk associate to other food, including formula). (NCT00930761)
Timeframe: At 60 days after the infant hospital discharge

Interventionparticipants (Number)
Control27
Music Therapy36

Maternal Breastfeeding at Infant Discharge

Maternal breastfeeding means exclusive maternal breastfeeding, predominant maternal breastfeeding (maternal milk associated to other liquid, except formula) and continuous maternal breastfeeding (maternal milk associate to other food, including formula). (NCT00930761)
Timeframe: At the time of the infant hospital discharge

Interventionparticipants (Number)
Control33
Music Therapy42

Number of Participants With Presence of Opioid Related Side Effects--Itching

(NCT03007966)
Timeframe: 24 hrs Post Nerve Block

InterventionParticipants (Count of Participants)
Ilioinguinal / Iliohypogastric Block2
Quadratus Lumborum Block3

Number of Participants With Presence of Opioid Related Side Effects--Itching

(NCT03007966)
Timeframe: 8 hrs Post Nerve Block

InterventionParticipants (Count of Participants)
Ilioinguinal / Iliohypogastric Block0
Quadratus Lumborum Block4

Number of Participants With Presence of Opioid Related Side Effects--Nausea

(NCT03007966)
Timeframe: 24 hrs Post Nerve Block

InterventionParticipants (Count of Participants)
Ilioinguinal / Iliohypogastric Block6
Quadratus Lumborum Block3

Number of Participants With Presence of Opioid Related Side Effects--Nausea

(NCT03007966)
Timeframe: 8 hrs Post Nerve Block

InterventionParticipants (Count of Participants)
Ilioinguinal / Iliohypogastric Block9
Quadratus Lumborum Block5

Number of Participants With Presence of Opioid Related Side Effects--Vomiting

(NCT03007966)
Timeframe: 24 hrs Post Nerve Block

InterventionParticipants (Count of Participants)
Ilioinguinal / Iliohypogastric Block3
Quadratus Lumborum Block2

Number of Participants With Presence of Opioid Related Side Effects--Vomiting

(NCT03007966)
Timeframe: 8 hrs Post Nerve Block

InterventionParticipants (Count of Participants)
Ilioinguinal / Iliohypogastric Block3
Quadratus Lumborum Block3

Post-operative Verbal Pain Score at Rest

Assessed on an 11 point (0-10) numeric analog scale with a higher score denoting a worse outcome (NCT03007966)
Timeframe: 24 hrs Post Nerve Block

Interventionscore on a scale (Mean)
Ilioinguinal / Iliohypogastric Block3
Quadratus Lumborum Block2.7

Post-operative Verbal Pain Score at Rest

Assessed on an 11-point (0-10) numeric analog scale with a higher score denoting a worse outcome (NCT03007966)
Timeframe: 8 hrs Post Nerve Block

Interventionscore on a scale (Mean)
Ilioinguinal / Iliohypogastric Block3.6
Quadratus Lumborum Block3.3

Post-operative Verbal Pain Score With Activity

Assessed on an 11 point (0-10) numeric analog scale with a higher score denoting a worse outcome (NCT03007966)
Timeframe: 24hrs Post Nerve Block

Interventionscore on a scale (Mean)
Ilioinguinal / Iliohypogastric Block4.9
Quadratus Lumborum Block5.3

Post-operative Verbal Pain Score With Movement

Assessed on an 11-point (0-10) numeric analog scale with a higher score denoting a worse outcome. (NCT03007966)
Timeframe: 8 hrs Post Nerve Block

Interventionscore on a scale (Mean)
Ilioinguinal / Iliohypogastric Block5.10
Quadratus Lumborum Block5.03

Time to First Oral Analgesic

When does the patient require their first post operative analgesic dose? (NCT03007966)
Timeframe: 24hrs Post Nerve Block

Interventionminutes (Median)
Ilioinguinal / Iliohypogastric Block141
Quadratus Lumborum Block91

Total Opioid Consumption

Total opioids consumed during the first 24hrs post operatively. Measured as 24hr Oxycodone Equivalent (NCT03007966)
Timeframe: 24 hrs Post Nerve Block

Interventionmilligrams (Mean)
Ilioinguinal / Iliohypogastric Block19.7
Quadratus Lumborum Block25.2

Change in Pelvic Flore Disability Index - 20 (PFDI-20) Scores From Baseline to 12 Months

"Symptomatic success was assessed by the pelvic floor disability index (PFDI-20) questionnaire. The PFDI-20 has 20 items within 3 sub-scales of symptoms (total of 20 items). Each item produces a response of 0 to 4, the average response in each sub-scale is multiplied by 25 to obtain the sub-scale score (range 0 to 100). The total score is the sum of the three sub-scale scores with a range of 0-300. Higher value for a time-point score indicates a greater degree of symptom bother.~The difference in scores across the study time-points was calculated by subtracting the total score at baseline from the score at 12 months post-operation. A negative value for the difference in scores from baseline to 12 months indicates symptom improvement, where the more negative the difference in score is the greater the improvement in symptoms." (NCT03565640)
Timeframe: Baseline and Month 12

Interventionscore on a scale (Mean)
Capio Slim Device-66.3
Anchorsure Device-71.0

Change in Symptomatic Success - PFIQ-7 Scores

"Symptomatic success will be assessed by the Pelvic Floor Impact Questionnaire - 7 (PFIQ-7). The PFIQ-7 has 7 items for each of 3 sub-scales (total of 21 items). Each item produces a response of 0 to 3, the average response in each sub-scale is multiplied by 100/3 to obtain the total scale score (range 0 to 100). The total score is the sum of the three sub-scale scores with a range of 0-300. Higher value for a time-point score indicates a greater degree of symptom bother.~The difference in scores across the study time-points was calculated by subtracting the total score at baseline from the score at 12 months post-operation. A negative value for the difference in scores from baseline to 12 months indicates symptom improvement, where the more negative the difference in score is the greater the improvement in symptoms." (NCT03565640)
Timeframe: Baseline and Month 12

Interventionscore on a scale (Mean)
Capio Slim Device-26.4
Anchorsure Device-40.6

POP-Q Stage Score

The stage is assigned as follows: 0 if there is no prolapse at all, 1 if there is prolapse but the leading point is not within 1cm of the hymen, 2 if the leading point is within 1 cm of the hymen (from 1cm within the hymen to 1cm beyond the hymen), 3 if the leading point is more than 1cm from the hymen but less than 2cm from being completely prolapsed, and 4 if the leading point is within 2cm of being complete prolapsed. Therefore higher POP-Q stages correlate to a worse degree of prolapse than lower POP-Q stages. (NCT03565640)
Timeframe: at 12 MONTHS

InterventionUnits on a scale (Mean)
Capio Slim Device0.8
Anchorsure Device0.9

Change in Buttock and Posterior Thigh Pain

This will be assessed using the numeric rating scale (NRS). The score is 0-10, with higher scores denoting a greater degree of pain. (NCT03565640)
Timeframe: postoperative 12 month

,
Interventionscore on a scale (Mean)
Sacrospinous ligament fixation site Pain compared to preopWorst pain compared to preop
Anchorsure Device-0.2-1.5
Capio Slim Device-0.5-1.8

Quadriceps Motor Strength

Comparison of quadriceps motor strength at 6 hour post nerve block between two groups: adductor canal block and lumbar plexus block. The score range is 0-5, with higher scores denoting better outcomes. (NCT01818531)
Timeframe: 6 hours

Interventionunits on a scale (Mean)
Adductor Canal Block4
Lumbar Plexus Block2.5

Time to First Analgesic

Time to first analgesic between two groups: adductor canal block and lumbar plexus block. (NCT01818531)
Timeframe: 24 hours

Interventionminutes (Mean)
Adductor Canal Block601
Lumbar Plexus Block659

Opioid Consumption

Comparison of cumulative opioid consumption over 24 hour period between adductor canal block and lumbar plexus block. (NCT01818531)
Timeframe: 6, 12, 18, and 24 hours

,
Interventionmg (Mean)
6 hours12 hours18 hours24 hours
Adductor Canal Block1.51120.927.9
Lumbar Plexus Block2.510.320.732.1

Opioid Related Side Effects

Occurrence of opioid related side effects (nausea, vomiting and pruritus) between two groups: adductor canal block and lumbar plexus block. (NCT01818531)
Timeframe: 6, 12, 18, and 24 hours

,
Interventionevents (Number)
Nausea 6 hoursNausea 12 hoursNausea 18 hoursNausea 24 hoursVomiting 6 hoursVomiting 12 hoursVomiting 18 hoursVomiting 24 hoursPruritus 6 hoursPruritus 12 hoursPruritus 18 hoursPruritus 24 hours
Adductor Canal Block1410596624117510
Lumbar Plexus Block1516815863634513

Verbal Pain Scores at 6 Hours Post Nerve Blockade.

Comparison of verbal numerical pain scores at rest and with movement 6 hours following nerve blockade. The score range is 0-10 with higher scores denoting worse outcomes. (NCT01818531)
Timeframe: 6 hours post block.

,
Interventionscore on a scale (Mean)
restmovement
Adductor Canal Block11.6
Lumbar Plexus Block1.11.5

Duration of Labor Analgesia

Time in minutes from initiation of labor analgesia until delivery of the infant (NCT00443560)
Timeframe: Time form initiation of labor analgesia to delivery (up to 24 hours)

Interventionminutes (Median)
Instrumental Vaginal Delivery (IVD)420
Spontaneous Vaginal Delivery (SVD)300

Number of Parturients With a Decrease in the Infusion of Epidural Analgesia During Second Stage of Labor

At the request of the obstetric provider, second stage analgesia density was decreased by decreasing the basal infusion rate if there was dissatisfaction with the progress of labor or a perceived inability to push. The basal infusion was never totally discontinued. (NCT00443560)
Timeframe: Second stage of labor up to 3 hours

Interventionparticipants (Number)
Instrumental Vaginal Delivery (IVD)146
Spontaneous Vaginal Delivery (SVD)51

Number of Participants With Breakthrough Pain in the First Stage of Labor

Pain not responding to epidural analgesia in the first stage of labor was treated with bolus dose of bupivacaine 1.25 mg/mL or lidocaine 10 mg/mL, 10 to 15 mL. If pain relief was obtained the infusion concentration was increased. If the patient had no pain relief following the bolus injection, the epidural catheter was replaced. (NCT00443560)
Timeframe: Supplemental analgesia in first stage of labor (<24 hours)

,
Interventionparticipants (Number)
Supplemental bolusInfusion increaseConcentration increase
Instrumental Vaginal Delivery (IVD)80214932
Spontaneous Vaginal Delivery (SVD)2438719

Duration of Second Stage of Labor

(NCT02949271)
Timeframe: duration of labor, up to 24hrs

Interventionminutes (Median)
Programmed Intermittent Epidural Bolus44
Continuous Epidural Infusion63

Maximum Reported Labor Pain Score

Measured using a verbal analog pain scale of 1-10, where 0=no pain and 10=worst possible pain. (NCT02949271)
Timeframe: duration of labor, up to 24hrs

Interventionscore on a scale (Median)
Programmed Intermittent Epidural Bolus3
Continuous Epidural Infusion2

Number of Patient Controlled Epidural Analgesia (PCEA) Attempts

Determined by the number of times subject activates the PCEA pump (NCT02949271)
Timeframe: duration of labor, up to 24hrs

Interventionattempts (Median)
Programmed Intermittent Epidural Bolus0.75
Continuous Epidural Infusion0.63

Number of Subjects Experiencing Hypotension Requiring Vasopressor Treatment

Number of patients who needed a vasopressor medication to treat a drop in blood pressure (NCT02949271)
Timeframe: duration of labor, up to 24 hrs

InterventionParticipants (Count of Participants)
Programmed Intermittent Epidural Bolus8
Continuous Epidural Infusion3

Ratio of Patient Controlled Epidural Analgesia (PCEA) Successful Attempts to Unsuccessful Attempts

Ratio generated by the number of times subjects activates PCEA and receives additional anesthetic compared with times subject activates PCEA and does not receive additional anesthetic. (NCT02949271)
Timeframe: duration of labor, up to 24hrs

Interventionratio of attempts (Median)
Programmed Intermittent Epidural Bolus0.17
Continuous Epidural Infusion0.12

Volume of Local Anesthetic Received Through Patient Controlled Epidural Analgesia (PCEA) Per Hour

The volume of local anesthetic that the patient received through activation of the patient-controlled epidural analgesia system per hour. (NCT02949271)
Timeframe: duration of labor, up to 24hrs

Interventionmilliliters per hour (Median)
Programmed Intermittent Epidural Bolus4.03
Continuous Epidural Infusion4.52

Volume of Local Anesthetic Required Per Hour

The total volume of local anesthetic that the patient received from the CAPP pump per hour. (NCT02949271)
Timeframe: duration of labor, up to 24hrs

Interventionmilliliters per hour (Median)
Programmed Intermittent Epidural Bolus11.49
Continuous Epidural Infusion12.38

Degree of Motor Blockade Measured as Lowest Recorded Modified Bromage Score

The Modified Bromage Score ranges from 1-5. 1 = complete block, 2 = almost complete block, 3 = partial block, 4 = detectable weakness of hip flexion, and 5 = no detectable weakness of hip flexion while supine. (NCT02949271)
Timeframe: duration of labor, up to 24hrs

,
InterventionParticipants (Count of Participants)
Score of 5Score of 4Score of 3Score of 2Score of 1
Continuous Epidural Infusion2620321
Programmed Intermittent Epidural Bolus379410

Number of Subjects Who Were Satisfied With Procedure

"Determined using a 5-point scale where 1=very dissatisfied, 2=dissatisfied, 3=neutral, 4=satisfied, 5=very satisfied. Subjects were considered satisfied if selected very satisfied or satisfied on the patient questionnaire." (NCT02949271)
Timeframe: duration of labor, up to 24hrs

,
InterventionParticipants (Count of Participants)
Very satisfiedSatisfied
Continuous Epidural Infusion393
Programmed Intermittent Epidural Bolus359

Total Number of Subjects Experiencing Each Mode of Delivery

Modes of delivery: spontaneous vaginal delivery (SVD), assisted vaginal delivery (AVD), and caesarean delivery (CD) (NCT02949271)
Timeframe: duration of labor, up to 24hrs

,
InterventionParticipants (Count of Participants)
SVDAVDCD
Continuous Epidural Infusion37517
Programmed Intermittent Epidural Bolus41515

Analgesia Efficacy

Patients were asked to rate their average pain score using an 11-point verbal rating score (VRS)for pain (0 - 10: 0= no pain, 10= worst pain imaginable) between 1st and 2nd analgesia request. (NCT00380978)
Timeframe: At first and second analgesia requests

InterventionScores on a scale (Median)
Early Analgesia:Combined-spinal Epidural1
Systemic Analgesia5

Delivered by Cesarean Section

The decision to proceed to operative delivery was made by the obstetric team for maternal or fetal indications. (NCT00380978)
Timeframe: Time form initiation of labor analgesia to delivery (up to 24 hours)

Interventionparticipants (Number)
Early Analgesia:Combined-spinal Epidural134
Systemic Analgesia126

Duration of Labor

Labor was induced by initiating an oxytocin infusion or by infusing extra-amniotic saline followed by oxytocin. All participants had continuous external electronic fetal heart rate (FHR) monitoring and tocodynamometry. Internal fetal scalp electrodes were placed when the external tracing was not interpretable, and intrauterine pressure catheters were used to measure the intensity of contractions when deemed necessary by the obstetricians. Artificial rupture of membranes was performed, and nurses titrated oxytocin infusions according to institutional protocol. (NCT00380978)
Timeframe: Initiation of induction of labor to time of delivery

Interventionminutes (Median)
Early Analgesia:Combined-spinal Epidural528
Systemic Analgesia569

Instrumented Vaginal Delivery

The decision to proceed to assisted/instrumental delivery was made by the obstetric team for maternal or fetal indications. (NCT00380978)
Timeframe: At time of decision for delivery

Interventionparticipants (Number)
Early Analgesia:Combined-spinal Epidural57
Systemic Analgesia59

Neonatal Outcome (APGAR Score < 7 at 5 Minutes)

Infant's Apgar scores measured at 5 minutes of life and were assigned by nurses and pediatricians responsible for neonatal assessment. The Apgar score is determined by evaluating the newborn baby on five simple criteria on a scale from zero to two, then summing the five values. The categories are skin color, pulse, reflex to stimulation, muscle tome, and breathing. The test was done at one and five minutes after birth, and may be repeated later if the score is and remains low. Scores 3 and below are generally regarded as critically low, 4 to 6 fairly low, and 7 to 10 generally normal. (NCT00380978)
Timeframe: APGAR score at 5 minutes

Interventionparticipants (Number)
Early Analgesia:Combined-spinal Epidural14
Systemic Analgesia6

Vomiting

Vomiting during labor analgesia (NCT00380978)
Timeframe: Vomiting at second analgesia request

Interventionparticipants (Number)
Early Analgesia:Combined-spinal Epidural12
Systemic Analgesia61

Indication for Cesarean Delivery

The decision to proceed to operative delivery was made by the obstetric team for maternal or fetal indications. (NCT00380978)
Timeframe: At time of decision for delivery

,
Interventionparticipants (Number)
Arrested dilationArrested descentNon-reassuring fetal statusOther
Early Analgesia:Combined-spinal Epidural8518274
Systemic Analgesia8323164

Nausea

Participants were asked to rate their nausea (as none, mild, moderate, or severe) and report the presence or absence of vomiting. (NCT00380978)
Timeframe: At second analgesia request

,
Interventionparticipants (Number)
NoneMildModerateSevere
Early Analgesia:Combined-spinal Epidural3722552
Systemic Analgesia265694916

To Determine if a Difference in Pain Scale Ratings is Detectable Following Intramuscular Palivizumab Injection That Was Pre-treated With Placebo or Tetracaine.

Parent score 1-10 (1 representing no pain and 10 representing extreme pain) FLACC (Face, Legs, Activity, Cry, Consolability) Score 0-10 (at baseline and post injection) (0 representing no pain and 10 representing extreme pain) Change in FLACC score (NCT00484393)
Timeframe: 2 visits, 1 month apart

,
Interventionunits on a scale (Mean)
Parent scoreFLACC at baselineFLACC post injectionChange in FLACC
Placebo7.31.69.37.7
Tetracaine7.31.78.46.7

Is Chronic Opioid Treatment Associated With Changes in Adrenocorticotropic Hormone (ACTH), Cortisol, Luteinizing Hormone (LH) and Testosterone Secretion?

(NCT00737737)
Timeframe: 4 weeks

Interventionng/ml (Number)
OpioidNA
PlaceboNA

Is Placebo Analgesia Associated With a Similar Hormonal Response as Elicited by an Opioid Analgesic?

(NCT00737737)
Timeframe: 4 weeks

Interventionng/ml (Number)
OpioidNA
PlaceboNA

Pain With Intrauterine Device (IUD) Placement

Distance (mm) from the left of the 100-mm visual analog scale (reflecting magnitude of pain) recorded at time of IUD Placement. Scale range is from 0mm (no pain) to 100mm (worst pain possible). A lower score (less pain) is considered a better outcome. (NCT02219308)
Timeframe: Moment of IUD insertion

Interventionmm (Median)
No Paracervical Block (Sham PCB)54
Paracervical Block (PCB)33

Median Pain Scores for All Time Points

Distance (mm) from the left of the 100-mm visual analog scale of pain at various time points. Scale range is 0mm (no pain) to 100mm (worst pain possible). Lower scores are considered better outcomes. (NCT02219308)
Timeframe: Anticipation of procedure through 5 minutes after IUD placement

,
Interventionmm (Median)
Anticipated PainBaseline PainSpeculum InsertionCapped Needle or PCBTenaculum placementUterine SoundingIUD placement5 mins after IUD placementOverall pain
No Paracervical Block (Sham PCB)510681047542751
Paracervical Block (PCB)58010301530331230

Reviews

145 reviews available for fentanyl and Pain

ArticleYear
Sedoanalgesia with intravenous midazolam and fentanyl for angioplasty of dysfunctional arteriovenous access: A retrospective single-center analysis.
    The journal of vascular access, 2023, Volume: 24, Issue:4

    Topics: Aged; Angioplasty; Angioplasty, Balloon; Arteriovenous Shunt, Surgical; Fentanyl; Graft Occlusion, V

2023
Influence of ketamine versus fentanyl on pain relief for pediatric orthopedic emergencies: A meta-analysis of randomized controlled studies.
    Medicine, 2021, Oct-22, Volume: 100, Issue:42

    Topics: Adolescent; Child; Child, Preschool; Drug Administration Routes; Emergencies; Female; Fentanyl; Huma

2021
Analgesia for retinopathy of prematurity screening: A systematic review.
    Pain practice : the official journal of World Institute of Pain, 2022, Volume: 22, Issue:7

    Topics: Acetaminophen; Analgesia; Fentanyl; Humans; Infant, Newborn; Nitrous Oxide; Pain; Pain Measurement;

2022
Patterns of Palliation: A Review of Casualties That Received Pain Management Before Reaching Role 2 in Afghanistan.
    Military medicine, 2023, 01-04, Volume: 188, Issue:1-2

    Topics: Adult; Afghan Campaign 2001-; Afghanistan; Emergency Medical Services; Fentanyl; Humans; Ketamine; M

2023
α-2 agonists vs. fentanyl as adjuvants for spinal anesthesia in elective cesarean section: a meta-analysis.
    Minerva anestesiologica, 2023, Volume: 89, Issue:5

    Topics: Adjuvants, Anesthesia; Adjuvants, Pharmaceutic; Adrenergic alpha-2 Receptor Agonists; Anesthesia, Sp

2023
α-2 agonists vs. fentanyl as adjuvants for spinal anesthesia in elective cesarean section: a meta-analysis.
    Minerva anestesiologica, 2023, Volume: 89, Issue:5

    Topics: Adjuvants, Anesthesia; Adjuvants, Pharmaceutic; Adrenergic alpha-2 Receptor Agonists; Anesthesia, Sp

2023
α-2 agonists vs. fentanyl as adjuvants for spinal anesthesia in elective cesarean section: a meta-analysis.
    Minerva anestesiologica, 2023, Volume: 89, Issue:5

    Topics: Adjuvants, Anesthesia; Adjuvants, Pharmaceutic; Adrenergic alpha-2 Receptor Agonists; Anesthesia, Sp

2023
α-2 agonists vs. fentanyl as adjuvants for spinal anesthesia in elective cesarean section: a meta-analysis.
    Minerva anestesiologica, 2023, Volume: 89, Issue:5

    Topics: Adjuvants, Anesthesia; Adjuvants, Pharmaceutic; Adrenergic alpha-2 Receptor Agonists; Anesthesia, Sp

2023
Comparison of different delivery modalities of epidural analgesia and intravenous analgesia in labour: a systematic review and network meta-analysis.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2023, Volume: 70, Issue:3

    Topics: Analgesia, Epidural; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Analgesics; Analgesics,

2023
Effect of Fentanyl for Preterm Infants on Mechanical Ventilation: A Systematic Review and Meta-Analysis.
    Neonatology, 2023, Volume: 120, Issue:3

    Topics: Cerebral Hemorrhage; Child; Ductus Arteriosus, Patent; Fentanyl; Humans; Infant; Infant, Newborn; In

2023
Non-opioid analgesics for procedural pain in neonates.
    The Cochrane database of systematic reviews, 2023, 04-04, Volume: 4

    Topics: Aged; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Apnea; Body Wei

2023
Opioids for procedural pain in neonates.
    The Cochrane database of systematic reviews, 2023, 04-05, Volume: 4

    Topics: Analgesics; Analgesics, Opioid; Apnea; Bradycardia; Fentanyl; Humans; Hypotension; Infant; Infant, N

2023
Low-dose ketamine or opioids combined with propofol for procedural sedation in the emergency department: a systematic review.
    European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 2023, Aug-01, Volume: 30, Issue:4

    Topics: Analgesics, Opioid; Conscious Sedation; Emergency Service, Hospital; Fentanyl; Humans; Hypnotics and

2023
Opioids for procedural pain in neonates.
    The Cochrane database of systematic reviews, 2023, 06-23, Volume: 6

    Topics: Analgesics; Analgesics, Opioid; Apnea; Bradycardia; Fentanyl; Humans; Hypotension; Infant, Newborn;

2023
Intranasal analgesia for acute moderate to severe pain in children - a systematic review and meta-analysis.
    BMC pediatrics, 2023, 08-18, Volume: 23, Issue:1

    Topics: Analgesia; Child; Fentanyl; Humans; Ketamine; Ketorolac; Pain

2023
Pharmacological interventions for the management of pain and discomfort during lumbar puncture in newborn infants.
    The Cochrane database of systematic reviews, 2023, 09-28, Volume: 9

    Topics: Analgesics; Anesthetics, Local; Apnea; Bradycardia; Fentanyl; Humans; Hypnotics and Sedatives; Infan

2023
Opioid prescription patterns in Germany and the global opioid epidemic: Systematic review of available evidence.
    PloS one, 2019, Volume: 14, Issue:8

    Topics: Adult; Analgesics, Opioid; Cross-Sectional Studies; Drug Overdose; Female; Fentanyl; Germany; Humans

2019
Pharmacology of Common Analgesic and Sedative Drugs Used in the Neonatal Intensive Care Unit.
    Clinics in perinatology, 2019, Volume: 46, Issue:4

    Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; C

2019
The influence of pain, agitation, and their management on the immature brain.
    Pediatric research, 2020, Volume: 88, Issue:2

    Topics: Algorithms; Analgesics, Opioid; Brain; Chronic Pain; Dexmedetomidine; Fentanyl; Humans; Hypnotics an

2020
The influence of pain, agitation, and their management on the immature brain.
    Pediatric research, 2020, Volume: 88, Issue:2

    Topics: Algorithms; Analgesics, Opioid; Brain; Chronic Pain; Dexmedetomidine; Fentanyl; Humans; Hypnotics an

2020
The influence of pain, agitation, and their management on the immature brain.
    Pediatric research, 2020, Volume: 88, Issue:2

    Topics: Algorithms; Analgesics, Opioid; Brain; Chronic Pain; Dexmedetomidine; Fentanyl; Humans; Hypnotics an

2020
The influence of pain, agitation, and their management on the immature brain.
    Pediatric research, 2020, Volume: 88, Issue:2

    Topics: Algorithms; Analgesics, Opioid; Brain; Chronic Pain; Dexmedetomidine; Fentanyl; Humans; Hypnotics an

2020
Sufentanil versus fentanyl for pain relief in labor involving combined spinal-epidural analgesia: a systematic review and meta-analysis of randomized controlled trials.
    European journal of clinical pharmacology, 2020, Volume: 76, Issue:4

    Topics: Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Apgar Score; Female; Fentanyl; Huma

2020
Reasons to avoid fentanyl.
    Annals of palliative medicine, 2020, Volume: 9, Issue:2

    Topics: Analgesics, Opioid; Fentanyl; Humans; Narcotics; Opioid-Related Disorders; Pain; Public Health; Unit

2020
Opioid rotation from transdermal fentanyl to continuous subcutaneous hydromorphone in a cachectic patient: A case report and review of the literature.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2021, Volume: 27, Issue:1

    Topics: Administration, Cutaneous; Analgesics, Opioid; Cachexia; Canada; Female; Fentanyl; Humans; Hydromorp

2021
Oxycodone versus other opioid analgesics after laparoscopic surgery: a meta-analysis.
    European journal of medical research, 2021, Jan-09, Volume: 26, Issue:1

    Topics: Alfentanil; Analgesics, Opioid; Fentanyl; Humans; Laparoscopy; Morphine; Oxycodone; Pain; Pain Manag

2021
Challenges of post-authorization safety studies: Lessons learned and results of a French study of fentanyl buccal tablet.
    Pharmacoepidemiology and drug safety, 2018, Volume: 27, Issue:5

    Topics: Administration, Buccal; Analgesics, Opioid; Diaries as Topic; Fentanyl; France; Humans; Intersectora

2018
Efficacy and feasibility of opioids for burn analgesia: An evidence-based qualitative review of randomized controlled trials.
    Burns : journal of the International Society for Burn Injuries, 2018, Volume: 44, Issue:2

    Topics: Administration, Cutaneous; Administration, Intranasal; Administration, Mucosal; Administration, Oral

2018
What Parenteral Opioids to Use in Face of Shortages of Morphine, Hydromorphone, and Fentanyl.
    The American journal of hospice & palliative care, 2018, Volume: 35, Issue:8

    Topics: Analgesics, Opioid; Buprenorphine; Fentanyl; Humans; Hydromorphone; Morphine; Nalbuphine; Pain

2018
DARK Classics in Chemical Neuroscience: Fentanyl.
    ACS chemical neuroscience, 2018, 10-17, Volume: 9, Issue:10

    Topics: Analgesics, Opioid; Anesthesia, General; Drug Industry; Drug Overdose; Epidemics; Fentanyl; Humans;

2018
The transdermal delivery of fentanyl.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2013, Volume: 84, Issue:3

    Topics: Administration, Cutaneous; Analgesics; Analgesics, Opioid; Buprenorphine; Clinical Trials as Topic;

2013
Transdermal fentanyl for cancer pain.
    The Cochrane database of systematic reviews, 2013, Oct-05, Issue:10

    Topics: Administration, Cutaneous; Analgesics, Opioid; Fentanyl; Humans; Methadone; Morphine; Neoplasms; Pai

2013
Impact of morphine, fentanyl, oxycodone or codeine on patient consciousness, appetite and thirst when used to treat cancer pain.
    The Cochrane database of systematic reviews, 2014, May-29, Issue:5

    Topics: Analgesics, Opioid; Appetite; Codeine; Consciousness; Fentanyl; Humans; Middle Aged; Morphine; Neopl

2014
[A case of Guillain-Barré syndrome with severe pain successfully controlled with acetaminophen, gabapentin, and parenterally infused fentanyl].
    No to hattatsu = Brain and development, 2014, Volume: 46, Issue:4

    Topics: Acetaminophen; Amines; Child; Cyclohexanecarboxylic Acids; Drug Combinations; Fentanyl; Gabapentin;

2014
[New option in the management of cancer pain in Hungary: short acting oral opioid therapy].
    Orvosi hetilap, 2015, Jun-21, Volume: 156, Issue:25

    Topics: Administration, Oral; Analgesics, Opioid; Analgesics, Short-Acting; Drug Administration Schedule; Dr

2015
Opioid Pharmacokinetics-Pharmacodynamics: Clinical Implications in Acute Pain Management in Trauma.
    The Annals of pharmacotherapy, 2016, Volume: 50, Issue:3

    Topics: Analgesics, Opioid; Fentanyl; Humans; Hydromorphone; Morphine; Pain; Pain Management; Pain Measureme

2016
Pharmacological and non-pharmacological interventions for reducing rocuronium bromide induced pain on injection in children and adults.
    The Cochrane database of systematic reviews, 2016, Feb-12, Volume: 2

    Topics: Acetaminophen; Adult; Analgesics, Opioid; Androstanols; Anesthetics, Local; Child; Fentanyl; Humans;

2016
[Analysis of the accessibility of short acting oral opioids in Hungary].
    Orvosi hetilap, 2016, May-01, Volume: 157, Issue:18

    Topics: Administration, Oral; Analgesics, Opioid; Analgesics, Short-Acting; Drug Industry; Education, Medica

2016
The use of opioids in cancer patients with renal impairment-a systematic review.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2017, Volume: 25, Issue:2

    Topics: Analgesics, Opioid; Drug-Related Side Effects and Adverse Reactions; Fentanyl; Humans; Neoplasms; Pa

2017
Analgesia in the surgical intensive care unit.
    Postgraduate medical journal, 2017, Volume: 93, Issue:1095

    Topics: Acetaminophen; Amines; Analgesics; Analgesics, Opioid; Anesthesia, Conduction; Anesthetics, Local; C

2017
[Driving ability under opioids: current assessment of published studies].
    Deutsche medizinische Wochenschrift (1946), 2008, Volume: 133 Suppl 2

    Topics: Accidents, Traffic; Administration, Cutaneous; Analgesics, Opioid; Automobile Driving; Buprenorphine

2008
Pharmacotherapeutic management of breakthrough pain in patients with chronic persistent pain.
    The American journal of managed care, 2008, Volume: 14, Issue:5 Suppl 1

    Topics: Analgesics, Opioid; Chronic Disease; Fentanyl; Humans; Pain

2008
[Generics in pain therapy].
    MMW Fortschritte der Medizin, 2008, Oct-16, Volume: 150, Issue:42

    Topics: Administration, Cutaneous; Administration, Oral; Aged; Analgesics, Opioid; Chronic Disease; Drugs, G

2008
[Difference in tolerance to anti-hyperalgesic effect and its molecular mechanisms between chronic treatment with morphine, fentanyl and oxycodone in a chronic pain-like state].
    Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 2008, Volume: 28, Issue:5-6

    Topics: Analgesics, Opioid; Animals; beta-Endorphin; Chronic Disease; Disease Models, Animal; Drug Tolerance

2008
Pediatric palliative care: use of opioids for the management of pain.
    Paediatric drugs, 2009, Volume: 11, Issue:2

    Topics: Administration, Cutaneous; Administration, Oral; Analgesics, Opioid; Buprenorphine; Child; Delayed-A

2009
Treatment strategies for cancer patients with breakthrough pain.
    Expert opinion on pharmacotherapy, 2009, Volume: 10, Issue:6

    Topics: Analgesics, Opioid; Animals; Fentanyl; Humans; Neoplasms; Pain; Pain Measurement; Treatment Outcome

2009
Opioids in people with cancer-related pain.
    BMJ clinical evidence, 2008, Jul-31, Volume: 2008

    Topics: Administration, Oral; Analgesics; Analgesics, Opioid; Codeine; Fentanyl; Humans; Methadone; Neoplasm

2008
The role of transdermal fentanyl patches in the effective management of cancer pain.
    International journal of palliative nursing, 2009, Volume: 15, Issue:7

    Topics: Acute Disease; Administration, Cutaneous; Analgesics, Opioid; Chemistry, Pharmaceutical; Chronic Dis

2009
The role of fentanyl in cancer-related pain.
    Journal of palliative medicine, 2009, Volume: 12, Issue:10

    Topics: Analgesics, Opioid; Fentanyl; Humans; Neoplasms; Pain; Palliative Care; United States

2009
Transdermal fentanyl as a front-line approach to moderate-severe pain: a meta-analysis of randomized clinical trials.
    Journal of palliative care, 2009,Autumn, Volume: 25, Issue:3

    Topics: Administration, Cutaneous; Analgesics, Opioid; Fentanyl; Humans; Pain; Randomized Controlled Trials

2009
Transdermal fentanyl: pharmacology and toxicology.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2009, Volume: 5, Issue:4

    Topics: Administration, Cutaneous; Analgesics, Opioid; Chronic Disease; Drug Carriers; Drug Overdose; Fentan

2009
Efficacy of intranasal fentanyl spray versus other opioids for breakthrough pain in cancer.
    Current medical research and opinion, 2010, Volume: 26, Issue:5

    Topics: Administration, Intranasal; Analgesics, Opioid; Fentanyl; Humans; Neoplasms; Pain; Placebos

2010
[Fetal pain and intrauterine analgesia/anesthesia: neuroanatomy, ontogenesis and physiology of pain perception].
    Orvosi hetilap, 2010, Mar-14, Volume: 151, Issue:11

    Topics: Analgesics, Opioid; Anesthetics, Intravenous; Brain; Cardiovascular System; Electroencephalography;

2010
Pharmacogenetics in obstetric anesthesia.
    Current opinion in anaesthesiology, 2010, Volume: 23, Issue:3

    Topics: Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spinal; Cesarean Section; Codeine; Female;

2010
Fentanyl patches: preventable overdose.
    Prescrire international, 2010, Volume: 19, Issue:105

    Topics: Administration, Cutaneous; Analgesics, Opioid; Chronic Disease; Drug Overdose; Fentanyl; Humans; Pai

2010
Breakthrough pain: progress in management.
    Current opinion in oncology, 2010, Volume: 22, Issue:4

    Topics: Administration, Intranasal; Administration, Oral; Analgesics, Opioid; Fentanyl; Humans; Neoplasms; P

2010
Efficacy and adverse effects of transdermal fentanyl and sustained-release oral morphine in treating moderate-severe cancer pain in Chinese population: a systematic review and meta-analysis.
    Journal of experimental & clinical cancer research : CR, 2010, Jun-09, Volume: 29

    Topics: Administration, Oral; Analgesics, Opioid; Cohort Studies; Fentanyl; Humans; Morphine; Neoplasms; Pai

2010
Treatment of breakthrough pain with fentanyl buccal tablet in opioid-tolerant patients with chronic pain: appropriate patient selection and management.
    Pain medicine (Malden, Mass.), 2010, Volume: 11, Issue:7

    Topics: Administration, Buccal; Algorithms; Analgesics, Opioid; Chronic Disease; Clinical Trials as Topic; D

2010
Intranasal fentanyl: from pharmacokinetics and bioavailability to current treatment applications.
    Expert review of anticancer therapy, 2010, Volume: 10, Issue:7

    Topics: Administration, Cutaneous; Administration, Intranasal; Administration, Oral; Adult; Aged; Biological

2010
Intranasal fentanyl: from pharmacokinetics and bioavailability to current treatment applications.
    Expert review of anticancer therapy, 2010, Volume: 10, Issue:7

    Topics: Administration, Cutaneous; Administration, Intranasal; Administration, Oral; Adult; Aged; Biological

2010
Intranasal fentanyl: from pharmacokinetics and bioavailability to current treatment applications.
    Expert review of anticancer therapy, 2010, Volume: 10, Issue:7

    Topics: Administration, Cutaneous; Administration, Intranasal; Administration, Oral; Adult; Aged; Biological

2010
Intranasal fentanyl: from pharmacokinetics and bioavailability to current treatment applications.
    Expert review of anticancer therapy, 2010, Volume: 10, Issue:7

    Topics: Administration, Cutaneous; Administration, Intranasal; Administration, Oral; Adult; Aged; Biological

2010
[The licit opioid consumption in Denmark].
    Ugeskrift for laeger, 2010, Nov-15, Volume: 172, Issue:46

    Topics: Analgesics, Opioid; Buprenorphine; Databases, Factual; Denmark; Drug Costs; Drug Utilization; Fentan

2010
[Solutions for the clinical problems of analgesics for cancer pain treatment in Japan].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2011, Volume: 131, Issue:1

    Topics: Acetaminophen; Analgesics; Drug Administration Routes; Fentanyl; Humans; Japan; Neoplasms; Oxycodone

2011
Long-term dosing, safety, and tolerability of fentanyl buccal tablet in the management of noncancer-related breakthrough pain in opioid-tolerant patients.
    Current medical research and opinion, 2011, Volume: 27, Issue:4

    Topics: Administration, Buccal; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Controlled C

2011
Integrated strategies for the successful management of breakthrough cancer pain.
    Current opinion in supportive and palliative care, 2011, Volume: 5, Issue:1

    Topics: Adult; Aged; Analgesics, Opioid; Breast Neoplasms; Drug Therapy, Combination; Female; Fentanyl; Huma

2011
Transdermal opioids for cancer pain.
    Current opinion in supportive and palliative care, 2011, Volume: 5, Issue:1

    Topics: Administration, Cutaneous; Analgesics, Opioid; Buprenorphine; Evidence-Based Medicine; Fentanyl; Hum

2011
Fentanyl nasal spray for the treatment of cancer pain.
    Expert opinion on pharmacotherapy, 2011, Volume: 12, Issue:10

    Topics: Administration, Intranasal; Administration, Oral; Analgesics, Opioid; Drug Delivery Systems; Fentany

2011
Fentanyl pectin nasal spray: in breakthrough pain in opioid-tolerant adults with cancer.
    CNS drugs, 2011, Jun-01, Volume: 25, Issue:6

    Topics: Analgesics, Opioid; Drug Tolerance; Fentanyl; Humans; Nasal Sprays; Neoplasms; Pain; Pectins

2011
[Breakthrough pain--what to consider when treating with rapid onset opioids].
    MMW Fortschritte der Medizin, 2011, Jun-09, Volume: 153, Issue:23

    Topics: Administration, Intranasal; Administration, Oral; Administration, Sublingual; Algorithms; Chronic Di

2011
Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Bet 4: is intranasal fentanyl better than parenteral morphine for managing acute severe pain in children?
    Emergency medicine journal : EMJ, 2011, Volume: 28, Issue:12

    Topics: Acute Disease; Administration, Intranasal; Analgesics, Opioid; Child; Child, Preschool; Evidence-Bas

2011
Systematic review of efficacy and safety of buprenorphine versus fentanyl or morphine in patients with chronic moderate to severe pain.
    Current medical research and opinion, 2012, Volume: 28, Issue:5

    Topics: Administration, Oral; Analgesics, Opioid; Buprenorphine; Chronic Pain; Constipation; Fentanyl; Human

2012
The history and pharmacology of fentanyl: relevance to a novel, long-acting transdermal fentanyl solution newly approved for use in dogs.
    Journal of veterinary pharmacology and therapeutics, 2012, Volume: 35 Suppl 2

    Topics: Analgesics, Opioid; Animals; Delayed-Action Preparations; Dog Diseases; Dogs; Fentanyl; Pain

2012
A review of the pharmacokinetic profile of transmucosal fentanyl formulations.
    Current medical research and opinion, 2012, Volume: 28, Issue:11

    Topics: Administration, Oral; Analgesics, Opioid; Fentanyl; Humans; Mouth Mucosa; Pain

2012
Limited evidence for intranasal fentanyl in the emergency department and the prehospital setting--a systematic review.
    Danish medical journal, 2013, Volume: 60, Issue:1

    Topics: Administration, Intranasal; Analgesics, Opioid; Emergency Medical Services; Emergency Service, Hospi

2013
The role of oral transmucosal fetanyl citrate in the management of breakthrough cancer pain.
    International journal of palliative nursing, 2002, Volume: 8, Issue:6

    Topics: Administration, Buccal; Analgesics, Opioid; Fentanyl; Humans; Neoplasms; Pain; Patient Selection

2002
Partial versus full agonists for opioid-mediated analgesia--focus on fentanyl and buprenorphine.
    Acta anaesthesiologica Belgica, 2002, Volume: 53, Issue:3

    Topics: Analgesics, Opioid; Animals; Buprenorphine; Drug Delivery Systems; Drug Tolerance; Fentanyl; Humans;

2002
The immune-suppressive effects of pain.
    Advances in experimental medicine and biology, 2003, Volume: 521

    Topics: Analgesics, Opioid; Animals; Bupivacaine; Cyclooxygenase Inhibitors; Fentanyl; Humans; Immune Tolera

2003
[Palliative care for colon cancer patients as total pain management].
    Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 7

    Topics: Analgesia, Epidural; Anticonvulsants; Antidepressive Agents; Colonic Neoplasms; Drug Therapy, Combin

2003
Benefit-risk assessment of transdermal fentanyl for the treatment of chronic pain.
    Drug safety, 2003, Volume: 26, Issue:13

    Topics: Administration, Cutaneous; Analgesics, Opioid; Body Weight; Chronic Disease; Female; Fentanyl; Human

2003
Morphine is not the only analgesic in palliative care: literature review.
    Journal of advanced nursing, 2004, Volume: 45, Issue:5

    Topics: Analgesics; Analgesics, Opioid; Fentanyl; Humans; Ketamine; Methadone; Morphine; Neoplasms; Pain; Pa

2004
Clinical experience with transdermal fentanyl for the treatment of cancer pain in Germany.
    The Keio journal of medicine, 2004, Volume: 53, Issue:1

    Topics: Administration, Cutaneous; Clinical Trials as Topic; Constipation; Fentanyl; Germany; Humans; Narcot

2004
Efficacy and safety of transdermal fentanyl and sustained-release oral morphine in patients with cancer and chronic non-cancer pain.
    Current medical research and opinion, 2004, Volume: 20, Issue:9

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics, Opioid;

2004
Managing breakthrough pain: a clinical review with three case studies using oral transmucosal fentanyl citrate.
    Clinical journal of oncology nursing, 2004, Volume: 8, Issue:5

    Topics: Administration, Buccal; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Drug Administration Sche

2004
Cancer pain management in children.
    Palliative medicine, 2004, Volume: 18, Issue:7

    Topics: Analgesics, Opioid; Anesthesia, Conduction; Child; Chronic Disease; Fentanyl; Humans; Injections, Sp

2004
What to learn from in vivo opioidergic brain imaging?
    European journal of pain (London, England), 2005, Volume: 9, Issue:2

    Topics: Analgesics, Opioid; Brain; Diprenorphine; Fentanyl; Humans; Ligands; Narcotic Antagonists; Pain; Pos

2005
Fentanyl for acute pain management.
    Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses, 2005, Volume: 20, Issue:4

    Topics: Administration, Cutaneous; Adult; Age Factors; Analgesia, Epidural; Analgesia, Patient-Controlled; A

2005
Patching together transdermal pain control options.
    Nursing, 2005, Volume: 35, Issue:9

    Topics: Administration, Cutaneous; Analgesics, Opioid; Fentanyl; Humans; Pain

2005
[Basic studies on cancer pain control].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:10

    Topics: Analgesics, Opioid; Animals; Constipation; Dose-Response Relationship, Drug; Fentanyl; Humans; Morph

2005
Opioids for the management of breakthrough (episodic) pain in cancer patients.
    The Cochrane database of systematic reviews, 2006, Jan-25, Issue:1

    Topics: Administration, Oral; Analgesics, Opioid; Fentanyl; Humans; Morphine; Neoplasms; Pain; Pain Measurem

2006
Transdermal buprenorphine in cancer pain and palliative care.
    Palliative medicine, 2006, Volume: 20 Suppl 1

    Topics: Administration, Cutaneous; Analgesics, Opioid; Buprenorphine; Drug Interactions; Fentanyl; Humans; N

2006
Cancer-related breakthrough pain.
    British journal of hospital medicine (London, England : 2005), 2006, Volume: 67, Issue:8

    Topics: Administration, Buccal; Administration, Oral; Analgesics, Opioid; Dose-Response Relationship, Drug;

2006
Opioids for management of breakthrough pain in cancer patients.
    American family physician, 2006, Dec-01, Volume: 74, Issue:11

    Topics: Administration, Oral; Analgesics, Opioid; Evidence-Based Medicine; Fentanyl; Humans; Neoplasms; Pain

2006
Fentanyl buccal tablet: in breakthrough pain in opioid-tolerant patients with cancer.
    Drugs, 2006, Volume: 66, Issue:18

    Topics: Administration, Buccal; Analgesics, Opioid; Animals; Drug Tolerance; Fentanyl; Humans; Mouth Mucosa;

2006
A titration strategy is needed to manage breakthrough cancer pain effectively: observations from data pooled from three clinical trials.
    Journal of palliative medicine, 2007, Volume: 10, Issue:1

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Female; Fentanyl; Humans;

2007
[Intranasal opioids for acute pain].
    Revista espanola de anestesiologia y reanimacion, 2006, Volume: 53, Issue:10

    Topics: Absorption; Acute Disease; Administration, Intranasal; Adult; Analgesia, Patient-Controlled; Analges

2006
Transdermal fentanyl in childhood and adolescence: a comprehensive literature review.
    The journal of pain, 2007, Volume: 8, Issue:3

    Topics: Administration, Cutaneous; Adolescent; Child; Drug Delivery Systems; Fentanyl; Humans; Narcotics; Pa

2007
Fentanyl buccal tablet: faster rescue analgesia for breakthrough pain?
    Future oncology (London, England), 2007, Volume: 3, Issue:4

    Topics: Administration, Buccal; Analgesia; Analgesics, Opioid; Fentanyl; Humans; Neoplasms; Pain; Randomized

2007
Oral transmucosal fentanyl citrate in cancer pain management: a practical application of nanotechnology.
    International journal of nanomedicine, 2007, Volume: 2, Issue:1

    Topics: Administration, Oral; Analgesics, Opioid; Clinical Trials as Topic; Drug Carriers; Fentanyl; Humans;

2007
The use of oral transmucosal fentanyl citrate during high-dose-rate gynecologic brachytherapy.
    Clinical journal of oncology nursing, 2007, Volume: 11, Issue:4

    Topics: Administration, Oral; Ambulatory Care; Analgesia; Analgesics, Opioid; Brachytherapy; Clinical Trials

2007
Actiq: an effective oral treatment for cancer-related breakthrough pain.
    British journal of community nursing, 2007, Volume: 12, Issue:7

    Topics: Administration, Buccal; Analgesics, Opioid; Chemistry, Pharmaceutical; Community Health Nursing; Dru

2007
The management of pain in children with life-limiting illnesses.
    Pediatric clinics of North America, 2007, Volume: 54, Issue:5

    Topics: Analgesics, Opioid; Child; Chronic Disease; Codeine; Fentanyl; Humans; Hydromorphone; Ketamine; Meth

2007
Fentanyl buccal tablet: rapid relief from breakthrough pain.
    Expert opinion on pharmacotherapy, 2007, Volume: 8, Issue:17

    Topics: Administration, Buccal; Analgesics, Opioid; Animals; Fentanyl; Humans; Pain; Pain Measurement; Patie

2007
Fentanyl buccal tablet.
    Drugs of today (Barcelona, Spain : 1998), 2008, Volume: 44, Issue:1

    Topics: Administration, Buccal; Analgesics, Opioid; Chronic Disease; Fentanyl; Humans; Neoplasms; Pain; Pain

2008
Adverse effects of transdermal opiates treating moderate-severe cancer pain in comparison to long-acting morphine: a meta-analysis and systematic review of the literature.
    Journal of palliative medicine, 2008, Volume: 11, Issue:3

    Topics: Administration, Cutaneous; Administration, Oral; Analgesics, Opioid; Buprenorphine; Delayed-Action P

2008
Management of pain in the older person with cancer. Part 2: treatment options.
    Oncology (Williston Park, N.Y.), 2008, Volume: 22, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Buprenorphine; Female; Fentany

2008
Effectiveness of opioids in the treatment of chronic non-cancer pain.
    Pain physician, 2008, Volume: 11, Issue:2 Suppl

    Topics: Analgesics, Opioid; Drug Administration Schedule; Fentanyl; Humans; Methadone; Morphine; Oxycodone;

2008
The role of the endogenous opioid system in the human stress response.
    The Psychiatric clinics of North America, 1983, Volume: 6, Issue:3

    Topics: Endorphins; Fentanyl; Humans; Hydrocortisone; Intraoperative Period; Morphine; Naloxone; Pain; Pain,

1983
Systemic analgesia during labor.
    Clinics in perinatology, 1982, Volume: 9, Issue:1

    Topics: Acid-Base Equilibrium; Analgesics; Animals; Child Behavior; Diazepam; Female; Fentanyl; Fetal Heart;

1982
Recent advances in acute pain management.
    Current problems in pediatrics, 1995, Volume: 25, Issue:3

    Topics: Acute Disease; Administration, Oral; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics;

1995
Transdermal fentanyl therapy: system design, pharmacokinetics and efficacy.
    Anti-cancer drugs, 1995, Volume: 6 Suppl 3

    Topics: Administration, Cutaneous; Drug Evaluation; Fentanyl; Humans; Neoplasms; Pain

1995
Oral transmucosal fentanyl. Help or hindrance?
    Drug safety, 1994, Volume: 11, Issue:5

    Topics: Absorption; Administration, Oral; Adolescent; Adult; Anti-Anxiety Agents; Child; Child, Preschool; C

1994
Comment: transdermal fentanyl.
    The Annals of pharmacotherapy, 1993, Volume: 27, Issue:6

    Topics: Administration, Cutaneous; Adult; Chronic Disease; Clinical Trials as Topic; Fentanyl; Humans; Neopl

1993
Transdermal fentanyl. A review of its pharmacological properties and therapeutic efficacy in pain control.
    Drugs, 1997, Volume: 53, Issue:1

    Topics: Analgesics, Opioid; Fentanyl; Humans; Pain

1997
[Transdermal opioid administration: the pain plaster].
    Nederlands tijdschrift voor geneeskunde, 1997, Apr-26, Volume: 141, Issue:17

    Topics: Administration, Cutaneous; Analgesics, Opioid; Fentanyl; Humans; Morphine; Pain; Pain, Intractable

1997
[Treatment of pain in oncology].
    Tumori, 1997, Volume: 83, Issue:2 Suppl

    Topics: Administration, Cutaneous; Analgesics, Opioid; Anesthetics, Dissociative; Diphosphonates; Fentanyl;

1997
Current strategies for pain control.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1997, Volume: 8 Suppl 3

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Bone Neoplasms; Fentanyl; Humans; Neoplasms; Pain; Pai

1997
Pharmacokinetic and pharmacodynamic issues in the treatment of breakthrough pain.
    Seminars in oncology, 1997, Volume: 24, Issue:5 Suppl 16

    Topics: Administration, Cutaneous; Administration, Intranasal; Administration, Oral; Administration, Subling

1997
Fentanyl in the treatment of cancer pain.
    Seminars in oncology, 1997, Volume: 24, Issue:5 Suppl 16

    Topics: Administration, Cutaneous; Administration, Oral; Biological Availability; Chronic Disease; Fentanyl;

1997
Caring for adults with chronic cancer pain.
    The American journal of nursing, 1998, Volume: 98, Issue:4

    Topics: Adult; Analgesics; Analgesics, Opioid; Chronic Disease; Female; Fentanyl; Humans; Neoplasms; Oncolog

1998
[Pharma clinics. How I treat...or preventing pain with "patches"].
    Revue medicale de Liege, 1998, Volume: 53, Issue:10

    Topics: Administration, Cutaneous; Analgesics, Opioid; Anesthetics, Local; Fentanyl; Lidocaine; Lidocaine, P

1998
A review of the use of fentanyl analgesia in the management of acute pain in adults.
    Anesthesiology, 1999, Volume: 90, Issue:2

    Topics: Adult; Analgesics, Opioid; Anesthetics, Intravenous; Fentanyl; Humans; Middle Aged; Pain

1999
Practice guidelines for cancer pain therapy. Issues pertinent to the revision of national guidelines.
    Oncology (Williston Park, N.Y.), 1998, Volume: 12, Issue:11A

    Topics: Analgesics; Analgesics, Opioid; Female; Fentanyl; Humans; Male; Morphine; Neoplasms; Pain; Pain Mana

1998
Alternatives to oral opioids for cancer pain.
    Oncology (Williston Park, N.Y.), 1999, Volume: 13, Issue:2

    Topics: Administration, Oral; Administration, Topical; Analgesics, Opioid; Buprenorphine; Fentanyl; Humans;

1999
Analgesics in the management of chronic pain. Part five: Step 3 parenteral analgesic drug therapy.
    Intensive & critical care nursing, 1999, Volume: 15, Issue:1

    Topics: Administration, Cutaneous; Analgesics; Chronic Disease; Fentanyl; Heroin; Humans; Infusions, Parente

1999
Opioid rotation for cancer pain: rationale and clinical aspects.
    Cancer, 1999, Nov-01, Volume: 86, Issue:9

    Topics: Analgesics, Opioid; Fentanyl; Humans; Hydromorphone; Methadone; Morphine; Narcotics; Neoplasms; Pain

1999
Managing breakthrough cancer pain: a new approach.
    Home healthcare nurse, 1999, Volume: 17, Issue:6 Suppl

    Topics: Administration, Oral; Adult; Analgesics, Opioid; Female; Fentanyl; Humans; Male; Middle Aged; Neopla

1999
Clinical pharmacokinetics of transdermal opioids: focus on transdermal fentanyl.
    Clinical pharmacokinetics, 2000, Volume: 38, Issue:1

    Topics: Administration, Cutaneous; Analgesics, Opioid; Animals; Fentanyl; Humans; Pain

2000
An alternative algorithm for dosing transdermal fentanyl for cancer-related pain.
    Oncology (Williston Park, N.Y.), 2000, Volume: 14, Issue:5

    Topics: Administration, Cutaneous; Algorithms; Analgesics, Opioid; Fentanyl; Humans; Neoplasms; Pain

2000
Results of the clinical trial of transdermal therapeutic system-fentanyl in strong opioid pre-treated adult patients with cancer-related pain.
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27 Suppl 2

    Topics: Administration, Cutaneous; Adult; Analgesics, Opioid; Clinical Trials as Topic; Drug Administration

2000
New developments in cancer pain therapy.
    Acta anaesthesiologica Sinica, 2000, Volume: 38, Issue:1

    Topics: Adrenal Medulla; Adrenergic alpha-Agonists; Analgesics, Opioid; Cell Transplantation; Cyclooxygenase

2000
Strong opioids for cancer pain.
    Journal of the Royal Society of Medicine, 2001, Volume: 94, Issue:1

    Topics: Analgesics, Opioid; Chronic Disease; Fentanyl; Humans; Morphine; Neoplasms; Neurotoxicity Syndromes;

2001
Contemporary drug therapy in palliative care: new directions.
    Cancer investigation, 2001, Volume: 19, Issue:4

    Topics: Adrenal Cortex Hormones; Analgesics; Anorexia; Antiemetics; Antitussive Agents; Cachexia; Cough; Dru

2001
[Issues in cancer pain management].
    Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59, Issue:9

    Topics: Analgesics, Opioid; Chronic Disease; Clinical Protocols; Fentanyl; Home Care Services; Humans; Morph

2001
Pain management in the critically ill child.
    Indian journal of pediatrics, 2001, Volume: 68, Issue:8

    Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Child; Child, Preschool; Critical Illness; Fentan

2001
Transdermal fentanyl: an updated review of its pharmacological properties and therapeutic efficacy in chronic cancer pain control.
    Drugs, 2001, Volume: 61, Issue:15

    Topics: Absorption; Administration, Cutaneous; Analgesia; Analgesics, Opioid; Digestive System; Drug Interac

2001
Treatment of cancer pain with transdermal fentanyl.
    The Lancet. Oncology, 2001, Volume: 2, Issue:3

    Topics: Administration, Cutaneous; Analgesics, Opioid; Fentanyl; Humans; Neoplasms; Pain; Pharmaceutical Pre

2001
[Pain relief during labor].
    Akusherstvo i ginekologiia, 1999, Volume: 38, Issue:1

    Topics: Analgesia, Epidural; Anesthetics; Bupivacaine; Female; Fentanyl; Humans; Labor, Obstetric; Nerve Blo

1999
[New opioid preparations in the treatment of pain].
    Duodecim; laaketieteellinen aikakauskirja, 1999, Volume: 115, Issue:20

    Topics: Administration, Cutaneous; Analgesics, Opioid; Clinical Competence; Fentanyl; Humans; Hydromorphone;

1999
E-TRANS fentanyl. ALZA.
    Current opinion in investigational drugs (London, England : 2000), 2002, Volume: 3, Issue:3

    Topics: Analgesics, Opioid; Animals; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic;

2002
[Cardiogenic shock: clinical manifestations and treatment].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1975, Jun-01, Volume: 28, Issue:11

    Topics: Blood Gas Analysis; Dextrans; Dopamine; Droperidol; Fentanyl; Hemodynamics; Humans; Isoproterenol; P

1975
[Pain control during the expulsion period in labor using bupivacaine and fentanyl].
    Minerva ginecologica, 1992, Volume: 44, Issue:10

    Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Bupivacaine; Drug Evaluation; Drug Therapy, Combinati

1992
Transdermal fentanyl.
    The Annals of pharmacotherapy, 1992, Volume: 26, Issue:11

    Topics: Administration, Cutaneous; Aged; Chemistry, Pharmaceutical; Chronic Disease; Clinical Trials as Topi

1992
Transdermal fentanyl: long-term analgesic studies.
    Journal of pain and symptom management, 1992, Volume: 7, Issue:3 Suppl

    Topics: Administration, Cutaneous; Chronic Disease; Clinical Trials as Topic; Fentanyl; Humans; Neoplasms; P

1992
Transdermal fentanyl in cancer pain.
    American family physician, 1992, Volume: 45, Issue:5

    Topics: Administration, Cutaneous; Fentanyl; Humans; Neoplasms; Pain

1992
Management of pain in the newborn infant.
    Journal of paediatrics and child health, 1991, Volume: 27, Issue:1

    Topics: Analgesics; Analgesics, Opioid; Fentanyl; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant

1991
Transdermally administered fentanyl for pain management.
    Clinical pharmacy, 1992, Volume: 11, Issue:1

    Topics: Administration, Cutaneous; Animals; Chronic Disease; Contraindications; Fentanyl; Humans; Neoplasms;

1992
[Use of epidural and intrathecal opiates in obstetrics].
    Annales francaises d'anesthesie et de reanimation, 1989, Volume: 8, Issue:6

    Topics: Adult; Analgesia, Epidural; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthe

1989
The pharmacologic management of pain in children.
    Comprehensive therapy, 1989, Volume: 15, Issue:10

    Topics: Analgesia, Epidural; Analgesics; Child; Child, Preschool; Codeine; Fentanyl; Humans; Infant; Meperid

1989
Management of pediatric pain with opioid analgesics.
    The Journal of pediatrics, 1988, Volume: 113, Issue:3

    Topics: Analgesics, Opioid; Child; Codeine; Fentanyl; Humans; Infant; Meperidine; Morphine; Narcotic Antagon

1988
Alfentanil in anesthesia and analgesia.
    Drug intelligence & clinical pharmacy, 1986, Volume: 20, Issue:5

    Topics: Alfentanil; Analgesia; Anesthesia; Blood Proteins; Drug Compounding; Drug Interactions; Fentanyl; Fo

1986
Evoked potentials as correlates of pain and pain relief in man.
    Agents and actions. Supplements, 1986, Volume: 19

    Topics: Acupuncture Therapy; Analgesics; Brain; Dental Pulp; Evoked Potentials; Fentanyl; Humans; Naloxone;

1986
Drug therapy: analgetic drugs--the potent analgetics.
    The New England journal of medicine, 1972, Feb-03, Volume: 286, Issue:5

    Topics: Analgesics; Blood Circulation; Fentanyl; Humans; Intestines; Levallorphan; Meperidine; Methadone; Me

1972
[Management of cardiogenic shock].
    Kardiologia polska, 1973, Volume: 16, Issue:2

    Topics: Bradycardia; Dextrans; Digitalis Glycosides; Droperidol; Electric Countershock; Electroconvulsive Th

1973

Trials

366 trials available for fentanyl and Pain

ArticleYear
'NOPAIN-ROP' trial: Intravenous fentanyl and intravenous ketamine for pain relief during laser photocoagulation for retinopathy of prematurity (ROP) in preterm infants: A randomised trial.
    BMJ open, 2021, 09-16, Volume: 11, Issue:9

    Topics: Fentanyl; Humans; Infant; Infant, Newborn; Infant, Premature; Ketamine; Lasers; Light Coagulation; P

2021
Comparing the Efficacy and Safety of Dexmedetomidine/Ketamine with Propofol/Fentanyl for Sedation in Colonoscopy Patients: A Doubleblinded Randomized Clinical Trial.
    CNS & neurological disorders drug targets, 2022, Volume: 21, Issue:8

    Topics: Apnea; Colonoscopy; Dexmedetomidine; Double-Blind Method; Fentanyl; Humans; Hypnotics and Sedatives;

2022
Pain control and reduction of opioid use associated with intracameral phenylephrine1.0%-ketorolac 0.3% administered during cataract surgery.
    Journal of cataract and refractive surgery, 2022, 07-01, Volume: 48, Issue:7

    Topics: Analgesics, Opioid; Cataract; Double-Blind Method; Epinephrine; Fentanyl; Humans; Ketorolac; Pain; P

2022
Dexmedetomidine Versus Midazolam for Sedation During Medical Thoracoscopy: A Pilot Randomized-Controlled Trial (RCT).
    Journal of bronchology & interventional pulmonology, 2022, Oct-01, Volume: 29, Issue:4

    Topics: Analgesics, Opioid; Conscious Sedation; Cough; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Seda

2022
A Randomized, Placebo-Controlled Study of Intranasal Fentanyl as an Analgesic Adjunct For Incision and Drainage of Abscess.
    The Journal of emergency medicine, 2022, Volume: 62, Issue:3

    Topics: Abscess; Administration, Intranasal; Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Dra

2022
Comparative study of the efficacy of dexmedetomidine and fentanyl on anxiety and pain of parturients with different COMTva1158met genotypes.
    BMC anesthesiology, 2022, 03-28, Volume: 22, Issue:1

    Topics: Analgesia, Epidural; Analgesics, Opioid; Anxiety; Dexmedetomidine; Female; Fentanyl; Genotype; Human

2022
Intranasal Fentanyl to Reduce Pain and Improve Oral Intake in the Management of Children With Painful Infectious Mouth Lesions.
    Pediatric emergency care, 2022, Aug-01, Volume: 38, Issue:8

    Topics: Acetaminophen; Administration, Intranasal; Analgesics, Opioid; Child; Child, Preschool; Communicable

2022
Ketamine Compared With Fentanyl for Surgical Abortion: A Randomized Controlled Trial.
    Obstetrics and gynecology, 2022, 09-01, Volume: 140, Issue:3

    Topics: Double-Blind Method; Female; Fentanyl; Humans; Ketamine; Midazolam; Pain; Pregnancy

2022
Comparison of Propofol-Fentanyl with Midazolam-Ketamine Combination in Pediatric Patients Undergoing Kidney Biopsy.
    Iranian journal of kidney diseases, 2022, Volume: 16, Issue:4

    Topics: Analgesics; Biopsy; Child; Fentanyl; Humans; Ketamine; Kidney; Midazolam; Pain; Propofol

2022
Transdermal fentanyl patch versus standard analgesia in postoperative oral submucous fibrosis patients: a triple blinded, randomised control trial.
    The British journal of oral & maxillofacial surgery, 2022, Volume: 60, Issue:9

    Topics: Analgesia; Analgesics, Opioid; Fentanyl; Humans; Oral Submucous Fibrosis; Pain; Transdermal Patch

2022
The Effects of Listening to the Qur'an in the Postoperative Management of the Patients Undergoing Laparoscopic Cholecystectomy in the Day Surgery Unit.
    Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses, 2023, Volume: 38, Issue:1

    Topics: Adult; Ambulatory Surgical Procedures; Analgesics, Opioid; Cholecystectomy, Laparoscopic; Fentanyl;

2023
A comparison of opioid-containing anesthesia versus opioid-free anesthesia using the Cortínez-Sepúlveda model on differential cytokine responses in obese patients undergoing gastric bypass surgery: a randomized controlled trial.
    BMC anesthesiology, 2022, 09-16, Volume: 22, Issue:1

    Topics: Adult; Analgesics, Opioid; Anesthesia; Cross-Sectional Studies; Cytokines; Female; Fentanyl; Gastric

2022
Value of Music and Nitrous Oxide for Pain Control during Extracorporeal Shock Wave Lithotripsy (ESWL).
    Archivos espanoles de urologia, 2022, Volume: 75, Issue:7

    Topics: Analgesics; Fentanyl; Humans; Ketoprofen; Lithiasis; Lithotripsy; Midazolam; Music; Nitrous Oxide; P

2022
The efficacy and safety of midazolam with fentanyl versus midazolam with ketamine for bedside invasive procedural sedation in pediatric oncology patients: A randomized, double-blinded, crossover trial.
    Pediatric hematology and oncology, 2022, Volume: 39, Issue:8

    Topics: Child; Cross-Over Studies; Fentanyl; Humans; Hypnotics and Sedatives; Ketamine; Midazolam; Neoplasms

2022
Gabapentin as an adjunct for pain management during dilation and evacuation: A double-blind randomized controlled trial.
    Contraception, 2023, Volume: 118

    Topics: Dilatation; Double-Blind Method; Female; Fentanyl; Gabapentin; Humans; Midazolam; Nausea; Pain; Pain

2023
Efficacy of type-I and type-II pectoral nerve blocks (PECS I and II) in patients undergoing mastectomy: a prospective randomised clinical trial.
    Anaesthesiology intensive therapy, 2022, Volume: 54, Issue:4

    Topics: Anesthetics, Local; Breast Neoplasms; Female; Fentanyl; Humans; Mastectomy; Middle Aged; Pain; Prosp

2022
Efficacy of type-I and type-II pectoral nerve blocks (PECS I and II) in patients undergoing mastectomy: a prospective randomised clinical trial.
    Anaesthesiology intensive therapy, 2022, Volume: 54, Issue:4

    Topics: Anesthetics, Local; Breast Neoplasms; Female; Fentanyl; Humans; Mastectomy; Middle Aged; Pain; Prosp

2022
Efficacy of type-I and type-II pectoral nerve blocks (PECS I and II) in patients undergoing mastectomy: a prospective randomised clinical trial.
    Anaesthesiology intensive therapy, 2022, Volume: 54, Issue:4

    Topics: Anesthetics, Local; Breast Neoplasms; Female; Fentanyl; Humans; Mastectomy; Middle Aged; Pain; Prosp

2022
Efficacy of type-I and type-II pectoral nerve blocks (PECS I and II) in patients undergoing mastectomy: a prospective randomised clinical trial.
    Anaesthesiology intensive therapy, 2022, Volume: 54, Issue:4

    Topics: Anesthetics, Local; Breast Neoplasms; Female; Fentanyl; Humans; Mastectomy; Middle Aged; Pain; Prosp

2022
Efficacy of electroacupuncture combined with intravenous patient-controlled analgesia after cesarean delivery: a randomized clinical trial.
    American journal of obstetrics & gynecology MFM, 2023, Volume: 5, Issue:2

    Topics: Analgesia, Patient-Controlled; Analgesics; Electroacupuncture; Female; Fentanyl; Humans; Pain; Pregn

2023
Efficacy of electroacupuncture combined with intravenous patient-controlled analgesia after cesarean delivery: a randomized clinical trial.
    American journal of obstetrics & gynecology MFM, 2023, Volume: 5, Issue:2

    Topics: Analgesia, Patient-Controlled; Analgesics; Electroacupuncture; Female; Fentanyl; Humans; Pain; Pregn

2023
Efficacy of electroacupuncture combined with intravenous patient-controlled analgesia after cesarean delivery: a randomized clinical trial.
    American journal of obstetrics & gynecology MFM, 2023, Volume: 5, Issue:2

    Topics: Analgesia, Patient-Controlled; Analgesics; Electroacupuncture; Female; Fentanyl; Humans; Pain; Pregn

2023
Efficacy of electroacupuncture combined with intravenous patient-controlled analgesia after cesarean delivery: a randomized clinical trial.
    American journal of obstetrics & gynecology MFM, 2023, Volume: 5, Issue:2

    Topics: Analgesia, Patient-Controlled; Analgesics; Electroacupuncture; Female; Fentanyl; Humans; Pain; Pregn

2023
LidocAine Versus Opioids In MyocarDial infarction: the AVOID-2 randomized controlled trial.
    European heart journal. Acute cardiovascular care, 2023, Jan-27, Volume: 12, Issue:1

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Fentanyl; Humans; Lidocaine; Pain; Prospective Studies

2023
LidocAine Versus Opioids In MyocarDial infarction: the AVOID-2 randomized controlled trial.
    European heart journal. Acute cardiovascular care, 2023, Jan-27, Volume: 12, Issue:1

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Fentanyl; Humans; Lidocaine; Pain; Prospective Studies

2023
LidocAine Versus Opioids In MyocarDial infarction: the AVOID-2 randomized controlled trial.
    European heart journal. Acute cardiovascular care, 2023, Jan-27, Volume: 12, Issue:1

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Fentanyl; Humans; Lidocaine; Pain; Prospective Studies

2023
LidocAine Versus Opioids In MyocarDial infarction: the AVOID-2 randomized controlled trial.
    European heart journal. Acute cardiovascular care, 2023, Jan-27, Volume: 12, Issue:1

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Fentanyl; Humans; Lidocaine; Pain; Prospective Studies

2023
Comparing the Effects of Low-Dose Ketamine, Fentanyl, and Morphine on Hemorrhagic Tolerance and Analgesia in Humans.
    Prehospital emergency care, 2023, Volume: 27, Issue:5

    Topics: Adult; Analgesia; Analgesics; Analgesics, Opioid; Cross-Over Studies; Emergency Medical Services; Fe

2023
Re: Re: Transdermal fentanyl patch versus standard analgesia in postoperative oral submucous fibrosis patients: A triple blinded, randomised control trial.
    The British journal of oral & maxillofacial surgery, 2023, Volume: 61, Issue:2

    Topics: Analgesia; Analgesics, Opioid; Fentanyl; Humans; Oral Submucous Fibrosis; Pain; Pain Management; Pai

2023
Intravenous paracetamol for persistent pain after endoscopic mucosal resection discriminates patients at risk of adverse events and those who can be safely discharged.
    Endoscopy, 2023, Volume: 55, Issue:7

    Topics: Acetaminophen; Colonoscopy; Endoscopic Mucosal Resection; Female; Fentanyl; Humans; Pain; Patient Di

2023
Analgesic effect of erector spinae plane block after cesarean section: A randomized controlled trial.
    Nigerian journal of clinical practice, 2023, Volume: 26, Issue:2

    Topics: Anesthesia, Spinal; Bupivacaine; Cesarean Section; Female; Fentanyl; Humans; Nerve Block; Pain; Preg

2023
Effects of fentanyl and sucrose on pain in retinopathy examinations with pain scale, near-infrared spectroscopy, and ultrasonography: a randomized trial.
    World journal of pediatrics : WJP, 2023, Volume: 19, Issue:9

    Topics: Fentanyl; Humans; Infant; Infant, Newborn; Oxygen; Pain; Pain Measurement; Retinopathy of Prematurit

2023
Comparison of the Analgesic Efficacy of Lidocaine Spray versus Tramadol and Fentanyl for Pain Control in Rib Fractures.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2023, Volume: 33, Issue:5

    Topics: Adult; Analgesics; Analgesics, Opioid; Anesthetics, Local; Fentanyl; Humans; Lidocaine; Middle Aged;

2023
Additive Value of Intranasal Fentanyl on Ibuprofen for Pain Management of Children With Moderate to Severe Headaches: A Randomized Controlled Trial.
    The Journal of emergency medicine, 2023, Volume: 65, Issue:2

    Topics: Adolescent; Analgesics, Opioid; Child; Double-Blind Method; Fentanyl; Headache; Humans; Ibuprofen; P

2023
The efficacy of intradermal sterile water application in severe renal colic: a randomised clinical trial.
    Urolithiasis, 2023, Oct-12, Volume: 51, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Fentanyl; Humans; Injectio

2023
The Impact of Head Elevation on Prevalence and Severity of Emergence Cough in Male Patients during Endotracheal Extubation.
    Medical science monitor : international medical journal of experimental and clinical research, 2023, Nov-30, Volume: 29

    Topics: Airway Extubation; Cough; Fentanyl; Humans; Intubation, Intratracheal; Male; Pain; Prevalence

2023
Pre-emptive analgesia with continuous fascia iliaca compartment block reduces postoperative delirium in elderly patients with hip fracture. A randomized controlled trial.
    Saudi medical journal, 2019, Volume: 40, Issue:9

    Topics: Aged; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Delirium; Double-Blind Method; Fe

2019
Video Education Reduces Pain and Anxiety Levels in Cancer Patients Who First Use Fentanyl Transdermal Patch: A Randomized Controlled Trial.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: Adult; Aged; Aged, 80 and over; Anxiety; Female; Fentanyl; Health Education; Humans; Male; Middle Ag

2020
Use of acupuncture as adjuvant analgesic technique in dogs undergoing thoracolumbar hemilaminectomy.
    Veterinary journal (London, England : 1997), 2020, Volume: 264

    Topics: Acupuncture Therapy; Analgesia; Analgesics, Opioid; Animals; Dog Diseases; Dogs; Fentanyl; Intervert

2020
Determination of equi-analgesic doses of inhaled methoxyflurane versus intravenous fentanyl using the cold pressor test in volunteers: a randomised, double-blinded, placebo-controlled crossover study.
    British journal of anaesthesia, 2021, Volume: 126, Issue:5

    Topics: Administration, Inhalation; Administration, Intravenous; Adult; Analgesics, Opioid; Anesthetics, Inh

2021
Midazolam as an active placebo in 3 fentanyl-validated nociceptive pain models.
    Pain, 2017, Volume: 158, Issue:7

    Topics: Adult; Analgesics; Cross-Over Studies; Double-Blind Method; Female; Fentanyl; Healthy Volunteers; Hu

2017
Evaluation of Paracervical Block and IV Sedation for Pain Management during Hysteroscopic Polypectomy: A Randomized Clinical Trial.
    Pain research & management, 2017, Volume: 2017

    Topics: Adult; Anesthesia, Obstetrical; Female; Fentanyl; Humans; Hysteroscopy; Iran; Lidocaine; Middle Aged

2017
Effect of propofol combined with opioids on cough reflex suppression in gastroscopy: study protocol for a double-blind randomized controlled trial.
    BMJ open, 2017, Sep-01, Volume: 7, Issue:9

    Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Antitussive Agents; Bridged Bicyclo Compounds, Heterocy

2017
Intravenous dexamethasone as an adjunct to improve labor analgesia: A randomized, double-blinded, placebo controlled clinical trial.
    Journal of clinical anesthesia, 2017, Volume: 43

    Topics: Adjuvants, Anesthesia; Administration, Intravenous; Adult; Analgesia, Epidural; Analgesia, Obstetric

2017
Effects of epidural anesthesia on postoperative nausea and vomiting in laparoscopic gynecological surgery: a randomized controlled trial.
    Journal of anesthesia, 2018, Volume: 32, Issue:4

    Topics: Adult; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, General; Antiemetics; Female; Fentanyl;

2018
Analgesic Efficacy of Intranasal Ketamine Versus Intranasal Fentanyl for Moderate to Severe Pain in Children: A Prospective, Randomized, Double-Blind Study.
    Pediatric emergency care, 2021, May-01, Volume: 37, Issue:5

    Topics: Administration, Intranasal; Adolescent; Analgesics; Child; Child, Preschool; Double-Blind Method; Fe

2021
Nitrous Oxide Compared With Intravenous Sedation for Second-Trimester Abortion: A Randomized Controlled Trial.
    Obstetrics and gynecology, 2018, Volume: 132, Issue:5

    Topics: Abortion, Induced; Adolescent; Adult; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics,

2018
[Comparison between Dexmedetomidine and Fentanyl Infusion during Fetoscopic Laser Photocoagulation for Twin to Twin Transfusion Syndrome].
    Masui. The Japanese journal of anesthesiology, 2017, Volume: 66, Issue:3

    Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Dexmedetomidine; Female; Fentanyl; Fetofetal T

2017
Effect of Intranasal Ketamine vs Fentanyl on Pain Reduction for Extremity Injuries in Children: The PRIME Randomized Clinical Trial.
    JAMA pediatrics, 2019, 02-01, Volume: 173, Issue:2

    Topics: Administration, Intranasal; Adolescent; Analgesics; Analgesics, Opioid; Child; Double-Blind Method;

2019
Prehospital intravenous fentanyl administered by ambulance personnel: a cluster-randomised comparison of two treatment protocols.
    Scandinavian journal of trauma, resuscitation and emergency medicine, 2019, Feb-07, Volume: 27, Issue:1

    Topics: Allied Health Personnel; Analgesics, Opioid; Denmark; Dose-Response Relationship, Drug; Emergency Me

2019
Evaluation of Analgesic Patches in Cynomolgus Macaques (
    Journal of the American Association for Laboratory Animal Science : JAALAS, 2019, 05-01, Volume: 58, Issue:3

    Topics: Administration, Cutaneous; Analgesics, Opioid; Animals; Area Under Curve; Buprenorphine; Cross-Over

2019
Analgesia-first sedation in critically ill adults: A U.S. pilot, randomized controlled trial.
    Journal of critical care, 2019, Volume: 53

    Topics: Aged; Analgesia; Analgesics, Opioid; Anesthesia; California; Clinical Protocols; Critical Illness; D

2019
Discovering Pain in Newborn Infants.
    Anesthesiology, 2019, Volume: 131, Issue:2

    Topics: Anesthetics, Intravenous; Ductus Arteriosus, Patent; Fentanyl; Humans; Infant, Newborn; Pain; Postop

2019
Pre-medication with sublingual fentanyl did not relieve pain associated with bone marrow aspiration and biopsy: a randomized feasibility trial.
    European journal of pain (London, England), 2013, Volume: 17, Issue:9

    Topics: Administration, Sublingual; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Biopsy, Needle; Bone

2013
Moderate procedural sedation and opioid analgesia during transradial coronary interventions to prevent spasm: a prospective randomized study.
    JACC. Cardiovascular interventions, 2013, Volume: 6, Issue:3

    Topics: Aged; Analgesics, Opioid; Arterial Occlusive Diseases; Chi-Square Distribution; Conscious Sedation;

2013
A novel approach to pharmaco-EEG for investigating analgesics: assessment of spectral indices in single-sweep evoked brain potentials.
    British journal of clinical pharmacology, 2013, Volume: 76, Issue:6

    Topics: Adult; Analgesics, Opioid; Brain; Buprenorphine; Cross-Over Studies; Data Interpretation, Statistica

2013
Efficacy and safety of continuous infusion of fentanyl for pain control in preterm newborns on mechanical ventilation.
    The Journal of pediatrics, 2013, Volume: 163, Issue:3

    Topics: Analgesics, Opioid; Double-Blind Method; Female; Fentanyl; Follow-Up Studies; Humans; Infant, Newbor

2013
Comparison of the efficacy of dexmedetomidine plus fentanyl patient-controlled analgesia with fentanyl patient-controlled analgesia for pain control in uterine artery embolization for symptomatic fibroid tumors or adenomyosis: a prospective, randomized st
    Journal of vascular and interventional radiology : JVIR, 2013, Volume: 24, Issue:6

    Topics: Adenomyosis; Adjuvants, Anesthesia; Analgesics, Non-Narcotic; Chemoembolization, Therapeutic; Dexmed

2013
Comparison of three methods of preventing rocuronium induced pain on injection using venous occlusion technique: a randomized prospective double blind controlled study.
    Middle East journal of anaesthesiology, 2013, Volume: 22, Issue:1

    Topics: Adult; Aged; Androstanols; Double-Blind Method; Female; Fentanyl; Humans; Injections, Intravenous; L

2013
A randomized crossover clinical trial to evaluate the efficacy of oral transmucosal fentanyl citrate in the treatment of dyspnea on exertion in patients with advanced cancer.
    The American journal of hospice & palliative care, 2015, Volume: 32, Issue:3

    Topics: Aged; Analgesics, Opioid; Dose-Response Relationship, Drug; Double-Blind Method; Dyspnea; Female; Fe

2015
Efficacy and safety of a six-hour continuous overlap method for converting intravenous to transdermal fentanyl in cancer pain.
    Journal of pain and symptom management, 2014, Volume: 48, Issue:1

    Topics: Administration, Cutaneous; Administration, Intravenous; Adult; Aged; Aged, 80 and over; Analgesics,

2014
Comparison of anaesthetic and analgesic effects of emulsified isoflurane used alone or combined with lidocaine and fentanyl in dogs.
    New Zealand veterinary journal, 2014, Volume: 62, Issue:3

    Topics: Analgesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics, Local; Animals; Dogs; Dru

2014
Lack of association between genetic variability and multiple pain-related outcomes in a large cohort of patients with advanced cancer: the European Pharmacogenetic Opioid Study (EPOS).
    BMJ supportive & palliative care, 2012, Volume: 2, Issue:4

    Topics: Analgesics, Opioid; Cohort Studies; Europe; Female; Fentanyl; Genetic Association Studies; Genetic V

2012
[Breakthrough pain treatment with sublingual fentanyl in patients with chronic cutaneous ulcers].
    Revista espanola de anestesiologia y reanimacion, 2014, Volume: 61, Issue:8

    Topics: Administration, Sublingual; Aged; Chronic Disease; Constipation; Female; Fentanyl; Humans; Male; Mid

2014
Pretreatment with remifentanil, fentanyl, or lidocaine to prevent withdrawal after rocuronium using venous occlusion technique in children and adolescents: a prospective randomized placebo-controlled double-blind study.
    Journal of anesthesia, 2014, Volume: 28, Issue:6

    Topics: Adolescent; Androstanols; Anesthesia, General; Child; Child, Preschool; Double-Blind Method; Female;

2014
Progressive change in joint degeneration in patients with knee or hip osteoarthritis treated with fentanyl in a randomized trial.
    Yonsei medical journal, 2014, Volume: 55, Issue:5

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Disease Progression; Female; Fentanyl; Humans; Male; Mi

2014
[Opioid induction using rapid release drugs and the shift to fentanyl patches].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2014, Volume: 41, Issue:7

    Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Analgesics, Opioid; Female; Fentanyl; Humans; Ma

2014
Dynamic interactions between plasma IL-1 family cytokines and central endogenous opioid neurotransmitter function in humans.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2015, Volume: 40, Issue:3

    Topics: Amygdala; Anxiety Disorders; Carbon Radioisotopes; Female; Fentanyl; Functional Neuroimaging; Humans

2015
A randomized controlled trial of fentanyl in the pre-emptive treatment of pain associated with turning in patients under mechanical ventilation: research protocol.
    Journal of advanced nursing, 2015, Volume: 71, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Critical Care; Double-Blind Method;

2015
Efficacy and safety of transdermal fentanyl for the treatment of oral mucositis pain caused by chemoradiotherapy in patients with esophageal squamous cell carcinoma.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2015, Volume: 23, Issue:3

    Topics: Administration, Cutaneous; Adult; Aged; Analgesics, Opioid; Carcinoma, Squamous Cell; Chemoradiother

2015
Comparison of intrathecal bupivacaine, levobupivacaine for cesarean section.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2014, Volume: 97, Issue:7

    Topics: Adult; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Cesarean Section; Double-Blind Method; F

2014
Comparing the pain of propofol via different combinations of fentanyl, sufentanil or remifentanil in gastrointestinal endoscopy.
    Acta cirurgica brasileira, 2014, Volume: 29, Issue:10

    Topics: Adult; Aged; Analgesics, Opioid; Drug Combinations; Endoscopy, Gastrointestinal; Female; Fentanyl; H

2014
Text messaging reduces analgesic requirements during surgery.
    Pain medicine (Malden, Mass.), 2015, Volume: 16, Issue:4

    Topics: Adult; Female; Fentanyl; Humans; Male; Narcotics; Pain; Pain Management; Text Messaging

2015
[Prevention of procedural pain in dressing changes of burn wounds by auricular injection of small-dose fentanyl].
    Zhongguo zhen jiu = Chinese acupuncture & moxibustion, 2014, Volume: 34, Issue:10

    Topics: Acupuncture Points; Adolescent; Adult; Aged; Burns; Female; Fentanyl; Humans; Male; Middle Aged; Pai

2014
Sedation and analgesia with fentanyl and etomidate for intrathecal injection in childhood leukemia patients.
    Medicine, 2015, Volume: 94, Issue:1

    Topics: Anesthetics, Intravenous; Child; Etomidate; Female; Fentanyl; Humans; Injections, Spinal; Leukemia;

2015
[Sedative effects of dexmedetomidine in post-operative elder patients on mechanical ventilation].
    Zhonghua yi xue za zhi, 2014, Nov-11, Volume: 94, Issue:41

    Topics: Aged; Analgesics; Delirium; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Sedatives; Intensive Ca

2014
Fosaprepitant versus ondansetron for the prevention of postoperative nausea and vomiting in patients who undergo gynecologic abdominal surgery with patient-controlled epidural analgesia: a prospective, randomized, double-blind study.
    Journal of anesthesia, 2015, Volume: 29, Issue:5

    Topics: Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Androstanols; Antieme

2015
The clinical effect of fentanyl in comparison with ketamine in analgesic effect for oncology procedures in children: a randomized, double-blinded, crossover trial.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2015, Volume: 98, Issue:4

    Topics: Adolescent; Analgesics; Analgesics, Opioid; Child; Child, Preschool; Cross-Over Studies; Double-Blin

2015
Improving the Management of Vaso-Occlusive Episodes in the Pediatric Emergency Department.
    Pediatrics, 2015, Volume: 136, Issue:4

    Topics: Administration, Intranasal; Adolescent; Analgesics; Analgesics, Opioid; Anemia, Sickle Cell; Child;

2015
Fentanyl as pre-emptive treatment of pain associated with turning mechanically ventilated patients: a randomized controlled feasibility study.
    Intensive care medicine, 2016, Volume: 42, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Critical Care; Double-Blind Method; Feasibility

2016
Comparison of Propofol, Propofol-Remifentanil, and Propofol-Fentanyl Administrations with Each Other Used for the Sedation of Patients to Undergo ERCP.
    BioMed research international, 2015, Volume: 2015

    Topics: Anesthetics, Intravenous; Cholangiopancreatography, Endoscopic Retrograde; Conscious Sedation; Dose-

2015
Does Fentanyl Lead to Opioid-induced Hyperalgesia in Healthy Volunteers?: A Double-blind, Randomized, Crossover Trial.
    Anesthesiology, 2016, Volume: 124, Issue:2

    Topics: Adult; Analgesics, Opioid; Cold Temperature; Cross-Over Studies; Dose-Response Relationship, Drug; D

2016
Does Fentanyl Lead to Opioid-induced Hyperalgesia in Healthy Volunteers?: A Double-blind, Randomized, Crossover Trial.
    Anesthesiology, 2016, Volume: 124, Issue:2

    Topics: Adult; Analgesics, Opioid; Cold Temperature; Cross-Over Studies; Dose-Response Relationship, Drug; D

2016
Does Fentanyl Lead to Opioid-induced Hyperalgesia in Healthy Volunteers?: A Double-blind, Randomized, Crossover Trial.
    Anesthesiology, 2016, Volume: 124, Issue:2

    Topics: Adult; Analgesics, Opioid; Cold Temperature; Cross-Over Studies; Dose-Response Relationship, Drug; D

2016
Does Fentanyl Lead to Opioid-induced Hyperalgesia in Healthy Volunteers?: A Double-blind, Randomized, Crossover Trial.
    Anesthesiology, 2016, Volume: 124, Issue:2

    Topics: Adult; Analgesics, Opioid; Cold Temperature; Cross-Over Studies; Dose-Response Relationship, Drug; D

2016
[Study of prevention and control of delirium in ventilated patients by simulating blockage of circadian rhythm with sedative in intensive care unit].
    Zhonghua wei zhong bing ji jiu yi xue, 2016, Volume: 28, Issue:1

    Topics: Analgesics; Circadian Rhythm; Critical Care; Delirium; Dexmedetomidine; Fentanyl; Humans; Hypnotics

2016
The median effective concentration (EC50) of propofol with different doses of fentanyl during colonoscopy in elderly patients.
    BMC anesthesiology, 2016, Apr-21, Volume: 16

    Topics: Aged; Aged, 80 and over; Anesthetics, Intravenous; Colonoscopy; Dose-Response Relationship, Drug; Do

2016
[A study of using dexmedetomidine in ventilator bundle treatment in an ICU].
    Zhonghua wei zhong bing ji jiu yi xue, 2015, Volume: 27, Issue:10

    Topics: Arterial Pressure; Blood Pressure; Delirium; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Sedati

2015
Routine vs. on-demand analgesia in colonoscopy: a randomized clinical trial.
    Endoscopy, 2016, Volume: 48, Issue:9

    Topics: Aged; Analgesia; Analgesics, Opioid; Anesthesia Recovery Period; Cecum; Colonoscopy; Female; Fentany

2016
Study protocol of a randomised controlled trial of intranasal ketamine compared with intranasal fentanyl for analgesia in children with suspected, isolated extremity fractures in the paediatric emergency department.
    BMJ open, 2016, 09-08, Volume: 6, Issue:9

    Topics: Administration, Intranasal; Adolescent; Analgesia; Analgesics; Analgesics, Opioid; Child; Child, Pre

2016
Entropy vs standard clinical monitoring using total intravenous anesthesia during transvaginal oocyte retrieval in patients for in vitro fertilization.
    Journal of clinical anesthesia, 2016, Volume: 34

    Topics: Adult; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Female; Fentanyl; Fer

2016
Time course of copeptin during a model of experimental pain and hyperalgesia: A randomised volunteer crossover trial.
    European journal of anaesthesiology, 2017, Volume: 34, Issue:5

    Topics: Adult; Analgesics, Opioid; Biomarkers; Cross-Over Studies; Double-Blind Method; Fentanyl; Glycopepti

2017
Follow-up at the corrected age of 24 months of preterm newborns receiving continuous infusion of fentanyl for pain control during mechanical ventilation.
    Pain, 2017, Volume: 158, Issue:5

    Topics: Anesthetics, Intravenous; Child Behavior Disorders; Child, Preschool; Cognition Disorders; Developme

2017
A randomized, open, parallel group, multicenter trial to investigate analgesic efficacy and safety of a new transdermal fentanyl patch compared to standard opioid treatment in cancer pain.
    Journal of pain and symptom management, 2008, Volume: 36, Issue:3

    Topics: Administration, Cutaneous; Analgesics, Opioid; Bandages; Delayed-Action Preparations; Europe; Female

2008
Omitting fentanyl reduces nausea and vomiting, without increasing pain, after sevoflurane for day surgery.
    European journal of anaesthesiology, 2008, Volume: 25, Issue:10

    Topics: Adult; Ambulatory Surgical Procedures; Female; Fentanyl; Humans; Male; Methyl Ethers; Nausea; Pain;

2008
Effects of morphine and fentanyl constant rate infusion on urine output in healthy and traumatized dogs.
    Veterinary anaesthesia and analgesia, 2008, Volume: 35, Issue:6

    Topics: Analgesics, Opioid; Animals; Dogs; Female; Fentanyl; Kidney; Kidney Function Tests; Male; Morphine;

2008
Pediatric oncology sedation trial (POST): A double-blind randomized study.
    Pediatric blood & cancer, 2008, Volume: 51, Issue:5

    Topics: Adolescent; Antiemetics; Antineoplastic Agents; Biopsy, Needle; Bone Marrow Examination; Child; Chil

2008
Pharmacokinetics and pharmacodynamics of intranasal versus intravenous fentanyl in patients with pain after oral surgery.
    The Annals of pharmacotherapy, 2008, Volume: 42, Issue:10

    Topics: Administration, Intranasal; Analgesics, Opioid; Biological Availability; Cross-Over Studies; Dose-Re

2008
Comparison of three doses of epidural fentanyl followed by bupivacaine and fentanyl for labor analgesia.
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:9

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Bupivacaine; Dose-Response Relationship, Drug; F

2008
Efficacy and safety of transdermal fentanyl for treatment of oral mucositis pain caused by chemotherapy.
    Expert opinion on pharmacotherapy, 2008, Volume: 9, Issue:18

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Analgesics, Opioid; Antineoplastic Combined Chem

2008
[Comparison of TD-fentanyl with sustained-release morphine in the pain treatment of patients with lung cancer].
    Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology, 2008, Volume: 20, Issue:3

    Topics: Administration, Cutaneous; Analgesics, Opioid; Chronic Disease; Delayed-Action Preparations; Female;

2008
Comparison of intrathecal magnesium, fentanyl, or placebo combined with bupivacaine 0.5% for parturients undergoing elective cesarean delivery.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:3

    Topics: Adult; Bupivacaine; Cesarean Section; Drug Combinations; Female; Fentanyl; Humans; Injections, Spina

2009
Randomized clinical trial of Entonox versus midazolam-fentanyl sedation for colonoscopy.
    The British journal of surgery, 2009, Volume: 96, Issue:4

    Topics: Administration, Inhalation; Adult; Aged; Anesthetics, Combined; Attitude of Health Personnel; Colono

2009
Fentanyl buccal tablet for the treatment of breakthrough pain in opioid-tolerant patients with chronic cancer pain: A long-term, open-label safety study.
    Cancer, 2009, Jun-01, Volume: 115, Issue:11

    Topics: Administration, Buccal; Analgesics, Opioid; Chronic Disease; Disease Progression; Drug Tolerance; Fe

2009
Analgesia during abdominal aortic aneurysm endovascular repair: remifentanil vs. fentanyl-midazolam--a randomized controlled trial.
    European journal of anaesthesiology, 2009, Volume: 26, Issue:9

    Topics: Aged; Analgesia; Analgesics, Opioid; Aortic Aneurysm, Abdominal; Area Under Curve; Blood Pressure; C

2009
Opioids switching with transdermal systems in chronic cancer pain.
    Journal of experimental & clinical cancer research : CR, 2009, May-07, Volume: 28

    Topics: Adult; Aged; Analgesia; Analgesics, Opioid; Buprenorphine; Chronic Disease; Female; Fentanyl; Humans

2009
Transdermal fentanyl in cachectic cancer patients.
    Pain, 2009, Volume: 144, Issue:1-2

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Analgesics, Opioid; Body Mass Index; Cachexia; C

2009
Nebulized fentanyl versus intravenous morphine in children with suspected limb fractures in the emergency department: a randomized controlled trial.
    Emergency medicine Australasia : EMA, 2009, Volume: 21, Issue:3

    Topics: Acute Disease; Administration, Inhalation; Adolescent; Analgesics, Opioid; Analysis of Variance; Chi

2009
Efficacy and tolerability of intranasal fentanyl spray 50 to 200 microg for breakthrough pain in patients with cancer: a phase III, multinational, randomized, double-blind, placebo-controlled, crossover trial with a 10-month, open-label extension treatmen
    Clinical therapeutics, 2009, Volume: 31, Issue:6

    Topics: Administration, Intranasal; Adult; Aged; Analgesics, Opioid; Cross-Over Studies; Disease Progression

2009
Modafinil reduces patient-reported tiredness after sedation/analgesia but does not improve patient psychomotor skills.
    Acta anaesthesiologica Scandinavica, 2010, Volume: 54, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Anesthesia Recovery Period; Anesthetics, Inha

2010
A comparison of intranasal fentanyl spray with oral transmucosal fentanyl citrate for the treatment of breakthrough cancer pain: an open-label, randomised, crossover trial.
    Current medical research and opinion, 2009, Volume: 25, Issue:11

    Topics: Administration, Intranasal; Administration, Oral; Adult; Algorithms; Cross-Over Studies; Dose-Respon

2009
A comparison of intranasal fentanyl spray with oral transmucosal fentanyl citrate for the treatment of breakthrough cancer pain: an open-label, randomised, crossover trial.
    Current medical research and opinion, 2009, Volume: 25, Issue:11

    Topics: Administration, Intranasal; Administration, Oral; Adult; Algorithms; Cross-Over Studies; Dose-Respon

2009
A comparison of intranasal fentanyl spray with oral transmucosal fentanyl citrate for the treatment of breakthrough cancer pain: an open-label, randomised, crossover trial.
    Current medical research and opinion, 2009, Volume: 25, Issue:11

    Topics: Administration, Intranasal; Administration, Oral; Adult; Algorithms; Cross-Over Studies; Dose-Respon

2009
A comparison of intranasal fentanyl spray with oral transmucosal fentanyl citrate for the treatment of breakthrough cancer pain: an open-label, randomised, crossover trial.
    Current medical research and opinion, 2009, Volume: 25, Issue:11

    Topics: Administration, Intranasal; Administration, Oral; Adult; Algorithms; Cross-Over Studies; Dose-Respon

2009
Fentanyl pre-treatment alleviates pain during injection of propofol-lipuro premixed with lignocaine.
    The Medical journal of Malaysia, 2008, Volume: 63, Issue:5

    Topics: Adult; Anesthesia; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; Drug Administr

2008
Efficacy and long-term tolerability of sublingual fentanyl orally disintegrating tablet in the treatment of breakthrough cancer pain.
    Current medical research and opinion, 2009, Volume: 25, Issue:12

    Topics: Administration, Sublingual; Adult; Aged; Aged, 80 and over; Algorithms; Analgesics, Opioid; Double-B

2009
Efficacy and long-term tolerability of sublingual fentanyl orally disintegrating tablet in the treatment of breakthrough cancer pain.
    Current medical research and opinion, 2009, Volume: 25, Issue:12

    Topics: Administration, Sublingual; Adult; Aged; Aged, 80 and over; Algorithms; Analgesics, Opioid; Double-B

2009
Efficacy and long-term tolerability of sublingual fentanyl orally disintegrating tablet in the treatment of breakthrough cancer pain.
    Current medical research and opinion, 2009, Volume: 25, Issue:12

    Topics: Administration, Sublingual; Adult; Aged; Aged, 80 and over; Algorithms; Analgesics, Opioid; Double-B

2009
Efficacy and long-term tolerability of sublingual fentanyl orally disintegrating tablet in the treatment of breakthrough cancer pain.
    Current medical research and opinion, 2009, Volume: 25, Issue:12

    Topics: Administration, Sublingual; Adult; Aged; Aged, 80 and over; Algorithms; Analgesics, Opioid; Double-B

2009
Intranasal fentanyl in 1-3-year-olds: a prospective study of the effectiveness of intranasal fentanyl as acute analgesia.
    Emergency medicine Australasia : EMA, 2009, Volume: 21, Issue:5

    Topics: Administration, Intranasal; Analgesics, Opioid; Child, Preschool; Emergency Medical Services; Female

2009
Intranasal fentanyl in 1-3-year-olds: a prospective study of the effectiveness of intranasal fentanyl as acute analgesia.
    Emergency medicine Australasia : EMA, 2009, Volume: 21, Issue:5

    Topics: Administration, Intranasal; Analgesics, Opioid; Child, Preschool; Emergency Medical Services; Female

2009
Intranasal fentanyl in 1-3-year-olds: a prospective study of the effectiveness of intranasal fentanyl as acute analgesia.
    Emergency medicine Australasia : EMA, 2009, Volume: 21, Issue:5

    Topics: Administration, Intranasal; Analgesics, Opioid; Child, Preschool; Emergency Medical Services; Female

2009
Intranasal fentanyl in 1-3-year-olds: a prospective study of the effectiveness of intranasal fentanyl as acute analgesia.
    Emergency medicine Australasia : EMA, 2009, Volume: 21, Issue:5

    Topics: Administration, Intranasal; Analgesics, Opioid; Child, Preschool; Emergency Medical Services; Female

2009
Hemispheric synchronized sounds and perioperative analgesic requirements.
    Anesthesia and analgesia, 2010, Jan-01, Volume: 110, Issue:1

    Topics: Acoustic Stimulation; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics; Analgesic

2010
A comparison of pretreatment with fentanyl and lidocaine preceded by venous occlusion for reducing pain on injection of propofol: a prospective, randomized, double-blind, placebo-controlled study in adult Japanese surgical patients.
    Clinical therapeutics, 2009, Volume: 31, Issue:10

    Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method;

2009
A comparison of pretreatment with fentanyl and lidocaine preceded by venous occlusion for reducing pain on injection of propofol: a prospective, randomized, double-blind, placebo-controlled study in adult Japanese surgical patients.
    Clinical therapeutics, 2009, Volume: 31, Issue:10

    Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method;

2009
A comparison of pretreatment with fentanyl and lidocaine preceded by venous occlusion for reducing pain on injection of propofol: a prospective, randomized, double-blind, placebo-controlled study in adult Japanese surgical patients.
    Clinical therapeutics, 2009, Volume: 31, Issue:10

    Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method;

2009
A comparison of pretreatment with fentanyl and lidocaine preceded by venous occlusion for reducing pain on injection of propofol: a prospective, randomized, double-blind, placebo-controlled study in adult Japanese surgical patients.
    Clinical therapeutics, 2009, Volume: 31, Issue:10

    Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method;

2009
Fentanyl buccal soluble film (FBSF) for breakthrough pain in patients with cancer: a randomized, double-blind, placebo-controlled study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21, Issue:6

    Topics: Administration, Buccal; Adult; Aged; Analgesics, Opioid; Dosage Forms; Dose-Response Relationship, D

2010
Sublingual administration of fentanyl to cancer patients is an effective treatment for breakthrough pain: results from a randomized phase II study.
    Palliative medicine, 2010, Volume: 24, Issue:3

    Topics: Administration, Sublingual; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Cross-Ov

2010
In-office thermachoice III ablation: a comparison of two anesthetic techniques.
    Gynecologic and obstetric investigation, 2010, Volume: 69, Issue:2

    Topics: Administration, Cutaneous; Ambulatory Surgical Procedures; Analgesics, Opioid; Anesthesia, Local; Co

2010
Transdermal fentanyl for pain caused by radiotherapy in head and neck cancer patients treated in an outpatient setting: a multicenter trial in Taiwan.
    Japanese journal of clinical oncology, 2010, Volume: 40, Issue:4

    Topics: Administration, Cutaneous; Adult; Aged; Analgesics, Opioid; Female; Fentanyl; Head and Neck Neoplasm

2010
[Effects of intravenous midazolam, fentanyl or ketamine on pain relief during performance of epidural anesthesia].
    Masui. The Japanese journal of anesthesiology, 2009, Volume: 58, Issue:12

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anesthesia, Epidural; Female; Fentanyl; Humans; Hypnoti

2009
Intranasal fentanyl versus placebo for pain in children during catheterization for voiding cystourethrography.
    Pediatric radiology, 2010, Volume: 40, Issue:7

    Topics: Administration, Intranasal; Analgesics, Opioid; Child; Child, Preschool; Double-Blind Method; Female

2010
Effects of intrathecal fentanyl on quality of spinal anesthesia in children undergoing inguinal hernia repair.
    Paediatric anaesthesia, 2010, Volume: 20, Issue:6

    Topics: Abdominal Pain; Adolescent; Anesthesia, Spinal; Anesthetics, Intravenous; Anesthetics, Local; Bupiva

2010
A comparison of change in the 0-10 numeric rating scale to a pain relief scale and global medication performance scale in a short-term clinical trial of breakthrough pain intensity.
    Anesthesiology, 2010, Volume: 112, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Aged; Cohort Studies; Cross-Over Studies; Double-Blind Meth

2010
Single-dose pharmacokinetics of fentanyl buccal soluble film.
    Pain medicine (Malden, Mass.), 2010, Volume: 11, Issue:7

    Topics: Administration, Buccal; Adult; Analgesics, Opioid; Area Under Curve; Biological Availability; Cross-

2010
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
    European journal of anaesthesiology, 2010, Volume: 27, Issue:7

    Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmede

2010
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
    European journal of anaesthesiology, 2010, Volume: 27, Issue:7

    Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmede

2010
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
    European journal of anaesthesiology, 2010, Volume: 27, Issue:7

    Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmede

2010
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
    European journal of anaesthesiology, 2010, Volume: 27, Issue:7

    Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmede

2010
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
    European journal of anaesthesiology, 2010, Volume: 27, Issue:7

    Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmede

2010
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
    European journal of anaesthesiology, 2010, Volume: 27, Issue:7

    Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmede

2010
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
    European journal of anaesthesiology, 2010, Volume: 27, Issue:7

    Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmede

2010
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
    European journal of anaesthesiology, 2010, Volume: 27, Issue:7

    Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmede

2010
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
    European journal of anaesthesiology, 2010, Volume: 27, Issue:7

    Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmede

2010
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
    European journal of anaesthesiology, 2010, Volume: 27, Issue:7

    Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmede

2010
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
    European journal of anaesthesiology, 2010, Volume: 27, Issue:7

    Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmede

2010
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
    European journal of anaesthesiology, 2010, Volume: 27, Issue:7

    Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmede

2010
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
    European journal of anaesthesiology, 2010, Volume: 27, Issue:7

    Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmede

2010
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
    European journal of anaesthesiology, 2010, Volume: 27, Issue:7

    Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmede

2010
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
    European journal of anaesthesiology, 2010, Volume: 27, Issue:7

    Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmede

2010
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
    European journal of anaesthesiology, 2010, Volume: 27, Issue:7

    Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmede

2010
[A prospective randomized comparison of nebulized morphine versus thoracic epidural analgesia in the management of thoracic trauma].
    Annales francaises d'anesthesie et de reanimation, 2010, Volume: 29, Issue:6

    Topics: Adult; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Female; Fentanyl; H

2010
Six- versus 12-h conversion method from intravenous to transdermal fentanyl in chronic cancer pain: a randomized study.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2011, Volume: 19, Issue:5

    Topics: Administration, Cutaneous; Aged; Analgesics, Opioid; Chronic Disease; Double-Blind Method; Female; F

2011
Long-term safety and tolerability of fentanyl buccal tablet for the treatment of breakthrough pain in opioid-tolerant patients with chronic pain: an 18-month study.
    Journal of pain and symptom management, 2010, Volume: 40, Issue:5

    Topics: Administration, Buccal; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Dise

2010
Pharmacokinetics, analgesic effect, and tolerability of a single preprocedural dose of intranasal fentanyl in patients undergoing drain removal after breast reduction or augmentation surgery: A prospective, randomized, double-blind, placebo-controlled stu
    Clinical therapeutics, 2010, Volume: 32, Issue:7

    Topics: Administration, Intranasal; Adolescent; Adult; Analgesics, Opioid; Device Removal; Double-Blind Meth

2010
A multicenter, placebo-controlled, double-blind, multiple-crossover study of Fentanyl Pectin Nasal Spray (FPNS) in the treatment of breakthrough cancer pain.
    Pain, 2010, Volume: 151, Issue:3

    Topics: Administration, Intranasal; Analgesics, Opioid; Cross-Over Studies; Double-Blind Method; Female; Fen

2010
A novel 12-week study, with three randomized, double-blind placebo-controlled periods to evaluate fentanyl buccal tablets for the relief of breakthrough pain in opioid-tolerant patients with noncancer-related chronic pain.
    Pain medicine (Malden, Mass.), 2010, Volume: 11, Issue:9

    Topics: Administration, Buccal; Adult; Analgesics, Opioid; Chronic Disease; Cross-Over Studies; Double-Blind

2010
[A phase II clinical study of once-a-day fentanyl citrate patch in patients with cancer pain--switching from once-every-three-days fentanyl patch to once-a-day fentanyl citrate patch].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:9

    Topics: Female; Fentanyl; Humans; Male; Middle Aged; Neoplasms; Pain

2010
The use of fentanyl buccal tablets as breakthrough medication in patients receiving chronic methadone therapy: an open label preliminary study.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2011, Volume: 19, Issue:3

    Topics: Administration, Buccal; Adult; Aged; Analgesics, Opioid; Dose-Response Relationship, Drug; Drug Tole

2011
Low doses of transdermal fentanyl in opioid-naive patients with cancer pain.
    Current medical research and opinion, 2010, Volume: 26, Issue:12

    Topics: Aged; Analgesia; Analgesics, Opioid; Dose-Response Relationship, Drug; Female; Fentanyl; Humans; Mal

2010
Pharmacokinetic/pharmacodynamic relationships of transdermal buprenorphine and fentanyl in experimental human pain models.
    Basic & clinical pharmacology & toxicology, 2011, Volume: 108, Issue:4

    Topics: Adult; Analgesics, Opioid; Buprenorphine; Capsaicin; Cold Temperature; Cross-Over Studies; Dose-Resp

2011
A prospective, randomized, double-blind, multicenter study comparing remifentanil with fentanyl in mechanically ventilated patients.
    Intensive care medicine, 2011, Volume: 37, Issue:3

    Topics: Aged; Analgesics, Opioid; Consciousness; Critical Care; Double-Blind Method; Endpoint Determination;

2011
Use of intranasal fentanyl for the relief of pediatric orthopedic trauma pain.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2010, Volume: 17, Issue:11

    Topics: Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Child, Preschool; Female; Fentany

2010
Use of intranasal fentanyl for the relief of pediatric orthopedic trauma pain.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2010, Volume: 17, Issue:11

    Topics: Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Child, Preschool; Female; Fentany

2010
Use of intranasal fentanyl for the relief of pediatric orthopedic trauma pain.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2010, Volume: 17, Issue:11

    Topics: Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Child, Preschool; Female; Fentany

2010
Use of intranasal fentanyl for the relief of pediatric orthopedic trauma pain.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2010, Volume: 17, Issue:11

    Topics: Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Child, Preschool; Female; Fentany

2010
Effect of transdermal opioids in experimentally induced superficial, deep and hyperalgesic pain.
    British journal of pharmacology, 2011, Volume: 164, Issue:3

    Topics: Administration, Cutaneous; Analgesics; Analgesics, Opioid; Buprenorphine; Capsaicin; Cross-Over Stud

2011
Long-term effectiveness and tolerability of sublingual fentanyl orally disintegrating tablet for the treatment of breakthrough cancer pain.
    Current medical research and opinion, 2011, Volume: 27, Issue:3

    Topics: Administration, Oral; Administration, Sublingual; Adult; Aged; Aged, 80 and over; Algorithms; Analge

2011
Efficacy of oxycodone/paracetamol for patients with bone-cancer pain: a multicenter, randomized, double-blinded, placebo-controlled trial.
    Journal of clinical pharmacy and therapeutics, 2012, Volume: 37, Issue:1

    Topics: Acetaminophen; Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Bone Neopla

2012
Efficacy of fentanyl and/or lidocaine on total antioxidants and total oxidants during craniotomy.
    Clinical medicine & research, 2011, Volume: 9, Issue:2

    Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Antioxidants; Craniotomy; Double-Blind Method;

2011
The efficacy and safety of fentanyl buccal tablet compared with immediate-release oxycodone for the management of breakthrough pain in opioid-tolerant patients with chronic pain.
    Anesthesia and analgesia, 2011, Volume: 112, Issue:3

    Topics: Administration, Buccal; Adult; Analgesics, Opioid; Chronic Disease; Cross-Over Studies; Disease Mana

2011
Consistency of efficacy, patient acceptability, and nasal tolerability of fentanyl pectin nasal spray compared with immediate-release morphine sulfate in breakthrough cancer pain.
    Journal of pain and symptom management, 2011, Volume: 41, Issue:2

    Topics: Administration, Intranasal; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Cross-Over Studies;

2011
Equivalency of two concentrations of fentanyl administered by the intranasal route for acute analgesia in children in a paediatric emergency department: a randomized controlled trial.
    Emergency medicine Australasia : EMA, 2011, Volume: 23, Issue:2

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Australia; Child; Child,

2011
Equivalency of two concentrations of fentanyl administered by the intranasal route for acute analgesia in children in a paediatric emergency department: a randomized controlled trial.
    Emergency medicine Australasia : EMA, 2011, Volume: 23, Issue:2

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Australia; Child; Child,

2011
Equivalency of two concentrations of fentanyl administered by the intranasal route for acute analgesia in children in a paediatric emergency department: a randomized controlled trial.
    Emergency medicine Australasia : EMA, 2011, Volume: 23, Issue:2

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Australia; Child; Child,

2011
Equivalency of two concentrations of fentanyl administered by the intranasal route for acute analgesia in children in a paediatric emergency department: a randomized controlled trial.
    Emergency medicine Australasia : EMA, 2011, Volume: 23, Issue:2

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Australia; Child; Child,

2011
Fentanyl pretreatment for alleviation of perineal symptoms following preoperative administration of intravenous dexamethasone sodium phosphate--a prospective, randomized, double blind, placebo controlled study.
    Middle East journal of anaesthesiology, 2010, Volume: 20, Issue:6

    Topics: Adult; Analgesics, Opioid; Dexamethasone; Double-Blind Method; Female; Fentanyl; Glucocorticoids; Hu

2010
Sublingual fentanyl orally disintegrating tablet in daily practice: efficacy, safety and tolerability in patients with breakthrough cancer pain.
    Current medical research and opinion, 2011, Volume: 27, Issue:7

    Topics: Administration, Sublingual; Adult; Aged; Aged, 80 and over; Algorithms; Analgesics, Opioid; Female;

2011
The effectiveness and adverse events of morphine versus fentanyl on a physician-staffed helicopter.
    The Journal of emergency medicine, 2012, Volume: 43, Issue:1

    Topics: Adult; Air Ambulances; Analgesics, Opioid; Double-Blind Method; Female; Fentanyl; Humans; Male; Morp

2012
Midazolam-ketamine combination for moderate sedation in upper GI endoscopy.
    Journal of pediatric gastroenterology and nutrition, 2012, Volume: 54, Issue:3

    Topics: Adjuvants, Anesthesia; Anesthetics, Dissociative; Child; Child, Preschool; Conscious Sedation; Deep

2012
Analgesia and endocrine surgical stress: effect of two analgesia protocols on cortisol and prolactin levels during abdominal aortic aneurysm endovascular repair.
    Neuro endocrinology letters, 2011, Volume: 32, Issue:4

    Topics: 17-alpha-Hydroxyprogesterone; Aged; Aged, 80 and over; Analgesics, Opioid; Aortic Aneurysm, Abdomina

2011
Sevoflurane to alleviate pain on propofol injection.
    Journal of anesthesia, 2011, Volume: 25, Issue:6

    Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Female; Fentanyl; Humans; Injections, Intr

2011
Moderate sedation for elective upper endoscopy with balanced propofol versus fentanyl and midazolam alone: a randomized clinical trial.
    Endoscopy, 2012, Volume: 44, Issue:1

    Topics: Aged; Anesthesia Recovery Period; Anesthetics, Intravenous; Apnea; Deep Sedation; Endoscopy, Digesti

2012
Intravenous ketamine is as effective as midazolam/fentanyl for procedural sedation and analgesia in the emergency department.
    The Medical journal of Malaysia, 2011, Volume: 66, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Conscious Sedation; Emergency

2011
Nitrous oxide/oxygen compared with fentanyl in reducing pain among adults with isolated extremity trauma: a randomized trial.
    Emergency medicine Australasia : EMA, 2011, Volume: 23, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthetics, Inhalation; Extremities

2011
A double-blind, placebo-controlled study on the effect of buprenorphine and fentanyl on descending pain modulation: a human experimental study.
    The Clinical journal of pain, 2012, Volume: 28, Issue:7

    Topics: Administration, Cutaneous; Adult; Analgesics, Opioid; Buprenorphine; Cross-Over Studies; Double-Blin

2012
Stress response and procedural pain in the preterm newborn: the role of pharmacological and non-pharmacological treatments.
    European journal of pediatrics, 2012, Volume: 171, Issue:6

    Topics: Analgesics, Opioid; Biomarkers; Blood Specimen Collection; Facilitated Tucking; Female; Fentanyl; Hu

2012
[Minimal dosages of fentanyl and sufentanil with bupivacaine for epidural analgesia in labor].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2011, Volume: 42, Issue:6

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Bupivacaine; Dose-Response R

2011
[Three-day-type transdermal fentanyl patch conversion by rapid titration method with short-acting oral oxycodone for cancer pain].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:3

    Topics: Administration, Cutaneous; Administration, Oral; Aged; Aged, 80 and over; Analgesics, Opioid; Drug T

2012
Music during interventional radiological procedures, effect on sedation, pain and anxiety: a randomised controlled trial.
    The British journal of radiology, 2012, Volume: 85, Issue:1016

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Anxiety; Female; Fentanyl; Humans; Hypnotics

2012
Efficacy and safety of fentanyl sublingual spray for the treatment of breakthrough cancer pain: a randomized, double-blind, placebo-controlled study.
    Current medical research and opinion, 2012, Volume: 28, Issue:5

    Topics: Administration, Sublingual; Aged; Analgesics, Opioid; Double-Blind Method; Female; Fentanyl; Humans;

2012
[A pilot study of the reduced effects of adverse events caused by oral morphine and oxycodone after rotating to fentanyl patch in patients with metastatic breast cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:4

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Breast Neoplasms; Drug Therapy, Combin

2012
Intranasal fentanyl versus intravenous morphine in the emergency department treatment of severe painful sickle cell crises in children: study protocol for a randomised controlled trial.
    Trials, 2012, May-30, Volume: 13

    Topics: Administration, Intranasal; Adolescent; Aerosols; Analgesics, Opioid; Anemia, Sickle Cell; Child; Ch

2012
Intranasal fentanyl versus intravenous morphine in the emergency department treatment of severe painful sickle cell crises in children: study protocol for a randomised controlled trial.
    Trials, 2012, May-30, Volume: 13

    Topics: Administration, Intranasal; Adolescent; Aerosols; Analgesics, Opioid; Anemia, Sickle Cell; Child; Ch

2012
Intranasal fentanyl versus intravenous morphine in the emergency department treatment of severe painful sickle cell crises in children: study protocol for a randomised controlled trial.
    Trials, 2012, May-30, Volume: 13

    Topics: Administration, Intranasal; Adolescent; Aerosols; Analgesics, Opioid; Anemia, Sickle Cell; Child; Ch

2012
Intranasal fentanyl versus intravenous morphine in the emergency department treatment of severe painful sickle cell crises in children: study protocol for a randomised controlled trial.
    Trials, 2012, May-30, Volume: 13

    Topics: Administration, Intranasal; Adolescent; Aerosols; Analgesics, Opioid; Anemia, Sickle Cell; Child; Ch

2012
Intranasal fentanyl versus intravenous morphine in the emergency department treatment of severe painful sickle cell crises in children: study protocol for a randomised controlled trial.
    Trials, 2012, May-30, Volume: 13

    Topics: Administration, Intranasal; Adolescent; Aerosols; Analgesics, Opioid; Anemia, Sickle Cell; Child; Ch

2012
Intranasal fentanyl versus intravenous morphine in the emergency department treatment of severe painful sickle cell crises in children: study protocol for a randomised controlled trial.
    Trials, 2012, May-30, Volume: 13

    Topics: Administration, Intranasal; Adolescent; Aerosols; Analgesics, Opioid; Anemia, Sickle Cell; Child; Ch

2012
Intranasal fentanyl versus intravenous morphine in the emergency department treatment of severe painful sickle cell crises in children: study protocol for a randomised controlled trial.
    Trials, 2012, May-30, Volume: 13

    Topics: Administration, Intranasal; Adolescent; Aerosols; Analgesics, Opioid; Anemia, Sickle Cell; Child; Ch

2012
Intranasal fentanyl versus intravenous morphine in the emergency department treatment of severe painful sickle cell crises in children: study protocol for a randomised controlled trial.
    Trials, 2012, May-30, Volume: 13

    Topics: Administration, Intranasal; Adolescent; Aerosols; Analgesics, Opioid; Anemia, Sickle Cell; Child; Ch

2012
Intranasal fentanyl versus intravenous morphine in the emergency department treatment of severe painful sickle cell crises in children: study protocol for a randomised controlled trial.
    Trials, 2012, May-30, Volume: 13

    Topics: Administration, Intranasal; Adolescent; Aerosols; Analgesics, Opioid; Anemia, Sickle Cell; Child; Ch

2012
Prospective randomized crossover evaluation of three anesthetic regimens for painful procedures in children with cancer.
    The Journal of pediatrics, 2013, Volume: 162, Issue:1

    Topics: Adolescent; Anesthesia; Anesthetics, Intravenous; Bone Marrow Examination; Child; Child, Preschool;

2013
Warm water infusion during sedated colonoscopy does not decrease amount of sedation medication used.
    Gastrointestinal endoscopy, 2012, Volume: 76, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cold Temperature; Colonoscopy; Double-Blind Method; Fema

2012
Randomised trial of magnesium in the treatment of Irukandji syndrome.
    Emergency medicine Australasia : EMA, 2012, Volume: 24, Issue:5

    Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Analysis of

2012
Analgesic effect of intrathecal neostigmine combined with bupivacaine and fentanyl.
    African journal of medicine and medical sciences, 2012, Volume: 41, Issue:2

    Topics: Abdomen; Adult; Analgesics; Anesthesia, Spinal; Anesthetics, Combined; Bupivacaine; Fentanyl; Hemody

2012
Enhanced temporal summation of second pain and its central modulation in fibromyalgia patients.
    Pain, 2002, Volume: 99, Issue:1-2

    Topics: Adult; Analgesics, Opioid; Cold Temperature; Female; Fentanyl; Fibromyalgia; Hot Temperature; Humans

2002
Opioid switching from morphine to transdermal fentanyl for toxicity reduction in palliative care.
    Palliative medicine, 2002, Volume: 16, Issue:5

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Cognition Disorders;

2002
Pain and distress from bone marrow aspirations and lumbar punctures.
    The Annals of pharmacotherapy, 2003, Volume: 37, Issue:1

    Topics: Adolescent; Anesthetics, Combined; Anesthetics, Intravenous; Anesthetics, Local; Biopsy, Needle; Bon

2003
Comparison of four strategies to reduce the pain associated with intravenous administration of rocuronium.
    British journal of anaesthesia, 2003, Volume: 90, Issue:3

    Topics: Adjuvants, Anesthesia; Androstanols; Anesthetics, Intravenous; Anesthetics, Local; Female; Fentanyl;

2003
Music decreases anxiety and provides sedation in extracorporeal shock wave lithotripsy.
    Urology, 2003, Volume: 61, Issue:2

    Topics: Adult; Aged; Anesthesia; Anesthetics, Intravenous; Anti-Anxiety Agents; Anxiety; Blood Pressure; Fem

2003
Music decreases anxiety and provides sedation in extracorporeal shock wave lithotripsy.
    Urology, 2003, Volume: 61, Issue:2

    Topics: Adult; Aged; Anesthesia; Anesthetics, Intravenous; Anti-Anxiety Agents; Anxiety; Blood Pressure; Fem

2003
Music decreases anxiety and provides sedation in extracorporeal shock wave lithotripsy.
    Urology, 2003, Volume: 61, Issue:2

    Topics: Adult; Aged; Anesthesia; Anesthetics, Intravenous; Anti-Anxiety Agents; Anxiety; Blood Pressure; Fem

2003
Music decreases anxiety and provides sedation in extracorporeal shock wave lithotripsy.
    Urology, 2003, Volume: 61, Issue:2

    Topics: Adult; Aged; Anesthesia; Anesthetics, Intravenous; Anti-Anxiety Agents; Anxiety; Blood Pressure; Fem

2003
Lumbar epidural fentanyl: segmental spread and effect on temporal summation and muscle pain.
    British journal of anaesthesia, 2003, Volume: 90, Issue:4

    Topics: Adult; Aged; Analgesia, Epidural; Analgesics, Opioid; Dose-Response Relationship, Drug; Double-Blind

2003
Small dose bupivacaine-fentanyl spinal analgesia combined with morphine for labor.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:1

    Topics: Adult; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Intravenous; Ane

2003
Effects of fentanyl on pain and hemodynamic response after retrobulbar block in patients having phacoemulsification.
    Journal of cataract and refractive surgery, 2003, Volume: 29, Issue:6

    Topics: Adult; Aged; Analgesia; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Intravenous; Anesthet

2003
Plasma fentanyl concentrations in awake cats and cats undergoing anesthesia and ovariohysterectomy using transdermal administration.
    Veterinary anaesthesia and analgesia, 2003, Volume: 30, Issue:4

    Topics: Administration, Cutaneous; Analgesics, Opioid; Anesthesia; Animals; Area Under Curve; Behavior, Anim

2003
The site of action of epidural fentanyl in humans: the difference between infusion and bolus administration.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:5

    Topics: Adult; Algorithms; Analgesia, Epidural; Analgesics, Opioid; Area Under Curve; Cross-Over Studies; Do

2003
Women experience more pain and require more morphine than men to achieve a similar degree of analgesia.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:5

    Topics: Abdomen; Analgesics, Opioid; Anesthetics, Intravenous; Cohort Studies; Female; Fentanyl; Humans; Lin

2003
Comparison of TTS-fentanyl with sustained-release oral morphine in the treatment of patients not using opioids for mild-to-moderate pain.
    Current medical research and opinion, 2003, Volume: 19, Issue:6

    Topics: Administration, Cutaneous; Administration, Oral; Aged; Analgesics, Opioid; Delayed-Action Preparatio

2003
The pharmacokinetics of transdermal fentanyl delivered with and without controlled heat.
    The journal of pain, 2003, Volume: 4, Issue:6

    Topics: Administration, Cutaneous; Adult; Analgesics, Opioid; Female; Fentanyl; Hot Temperature; Humans; Mal

2003
Long-term management of noncancer pain with transdermal therapeutic system-fentanyl.
    The journal of pain, 2003, Volume: 4, Issue:6

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Female; Fentanyl; Fol

2003
Intraoperative catecholamine release in brain-dead organ donors is not suppressed by administration of fentanyl.
    European journal of anaesthesiology, 2003, Volume: 20, Issue:12

    Topics: Adult; Analgesics, Opioid; Blood Pressure; Brain Death; Double-Blind Method; Epinephrine; Fentanyl;

2003
Radiotherapy plus either transdermal fentanyl or paracetamol and codeine for painful bone metastases: a randomised study of pain relief and quality of life.
    Current medical research and opinion, 2004, Volume: 20, Issue:2

    Topics: Acetaminophen; Activities of Daily Living; Administration, Cutaneous; Aged; Aged, 80 and over; Analg

2004
Propofol versus midazolam/fentanyl for outpatient colonoscopy: administration by nurses supervised by endoscopists.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2003, Volume: 1, Issue:6

    Topics: Adjuvants, Anesthesia; Adolescent; Adult; Aged; Ambulatory Care; Anesthesia Recovery Period; Attenti

2003
Propofol versus midazolam/fentanyl for outpatient colonoscopy: administration by nurses supervised by endoscopists.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2003, Volume: 1, Issue:6

    Topics: Adjuvants, Anesthesia; Adolescent; Adult; Aged; Ambulatory Care; Anesthesia Recovery Period; Attenti

2003
Propofol versus midazolam/fentanyl for outpatient colonoscopy: administration by nurses supervised by endoscopists.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2003, Volume: 1, Issue:6

    Topics: Adjuvants, Anesthesia; Adolescent; Adult; Aged; Ambulatory Care; Anesthesia Recovery Period; Attenti

2003
Propofol versus midazolam/fentanyl for outpatient colonoscopy: administration by nurses supervised by endoscopists.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2003, Volume: 1, Issue:6

    Topics: Adjuvants, Anesthesia; Adolescent; Adult; Aged; Ambulatory Care; Anesthesia Recovery Period; Attenti

2003
Use of transdermal fentanyl without prior opioid stabilization in patients with cancer pain.
    Current medical research and opinion, 2004, Volume: 20, Issue:3

    Topics: Administration, Cutaneous; Analgesics, Non-Narcotic; Analgesics, Opioid; Female; Fentanyl; Gastroint

2004
Pain management of cancer patients with transdermal fentanyl: a study of 1828 step I, II, & III transfers.
    The journal of pain, 2004, Volume: 5, Issue:2

    Topics: Administration, Cutaneous; Adult; Aged; Analgesics, Opioid; Female; Fentanyl; Follow-Up Studies; Hum

2004
A randomised crossover trial of patient controlled intranasal fentanyl and oral morphine for procedural wound care in adult patients with burns.
    Burns : journal of the International Society for Burn Injuries, 2004, Volume: 30, Issue:3

    Topics: Administration, Intranasal; Administration, Oral; Adolescent; Adult; Aged; Analgesia, Patient-Contro

2004
Transdermal fentanyl in HSCT patients: an open trial using transdermal fentanyl for the treatment of oral mucositis pain.
    Bone marrow transplantation, 2004, Volume: 33, Issue:12

    Topics: Administration, Cutaneous; Adult; Aged; Female; Fentanyl; Hematologic Neoplasms; Hematopoietic Stem

2004
A prospective randomized comparison of extensive prostate biopsy to standard biopsy with assessment of diagnostic yield, biopsy pain and morbidity.
    Prostate cancer and prostatic diseases, 2004, Volume: 7, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Biopsy; Conscious Sedation; Fentanyl; Huma

2004
Intrathecal midazolam II: combination with intrathecal fentanyl for labor pain.
    Anesthesia and analgesia, 2004, Volume: 98, Issue:6

    Topics: Adult; Analysis of Variance; Chi-Square Distribution; Drug Therapy, Combination; Female; Fentanyl; H

2004
Addition of a second opioid may improve opioid response in cancer pain: preliminary data.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2004, Volume: 12, Issue:11

    Topics: Adult; Aged; Analgesics, Opioid; Dose-Response Relationship, Drug; Drug Administration Schedule; Dru

2004
Patient-controlled analgesia with fentanyl for burn dressing changes.
    Anesthesia and analgesia, 2004, Volume: 99, Issue:2

    Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Bandages; Burns; Double-Blind Method; Elec

2004
Relative analgesic potency of fentanyl and sufentanil during intermediate-term infusions in patients after long-term opioid treatment for chronic pain.
    Pain, 2004, Volume: 110, Issue:1-2

    Topics: Adult; Aged; Chronic Disease; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administra

2004
A novel pain management strategy for combat casualty care.
    Annals of emergency medicine, 2004, Volume: 44, Issue:2

    Topics: Administration, Oral; Analgesics, Opioid; Fentanyl; Humans; Iraq; Military Personnel; Pain; Pain Mea

2004
Intrathecal fentanyl-induced pruritus during labour: the effect of prophylactic ondansetron.
    International journal of obstetric anesthesia, 2004, Volume: 13, Issue:1

    Topics: Adult; Analgesia, Obstetrical; Analgesics, Opioid; Double-Blind Method; Female; Fentanyl; Humans; In

2004
The effect of transdermal fentanyl treatment on serum cortisol concentrations in patients with non-cancer pain.
    Journal of pain and symptom management, 2004, Volume: 28, Issue:3

    Topics: Administration, Cutaneous; Adult; Analgesics, Opioid; Chronic Disease; Female; Fentanyl; Humans; Hyd

2004
Patient-controlled epidural analgesia in labour: the addition of fentanyl or clonidine to bupivacaine.
    Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology, 2004, Volume: 16, Issue:3

    Topics: Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; Blood Pressure; Bupivacaine;

2004
A randomised double-blind comparison of epidural fentanyl versus fentanyl and bupivicaine for pain relief in the second stage of labour.
    BJOG : an international journal of obstetrics and gynaecology, 2004, Volume: 111, Issue:10

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Anesthetics, Combined; Anesthetics, Local; Bupiv

2004
Remifentanil vs fentanyl/morphine for pain and stress control during pediatric cardiac surgery.
    Paediatric anaesthesia, 2004, Volume: 14, Issue:10

    Topics: Analgesics, Opioid; Blood Glucose; Blood Pressure; Cardiac Surgical Procedures; Child; Child, Presch

2004
Intrathecal labor analgesia using levobupivacaine 2.5 mg with fentanyl 25 microg--would half the dose suffice?
    Medical science monitor : international medical journal of experimental and clinical research, 2004, Volume: 10, Issue:10

    Topics: Adult; Analgesia, Obstetrical; Analgesics; Bupivacaine; Double-Blind Method; Female; Fentanyl; Human

2004
Propofol and sevoflurane during epidural/general anesthesia: comparison of early recovery characteristics and pain relief.
    Middle East journal of anaesthesiology, 2004, Volume: 17, Issue:5

    Topics: Abdomen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia Recovery Period;

2004
Transdermal fentanyl for the treatment of pain caused by rheumatoid arthritis.
    Rheumatology international, 2004, Volume: 24, Issue:6

    Topics: Administration, Cutaneous; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Drug Administrat

2004
Urine concentrations of fentanyl and norfentanyl during application of Duragesic transdermal patches.
    Journal of analytical toxicology, 2004, Volume: 28, Issue:6

    Topics: Administration, Cutaneous; Analgesics, Opioid; Chronic Disease; Delayed-Action Preparations; Fentany

2004
Value of fentanyl in flexible sigmoidoscopy.
    World journal of surgery, 2004, Volume: 28, Issue:9

    Topics: Analgesics, Opioid; Female; Fentanyl; Humans; Male; Middle Aged; Pain; Preoperative Care; Prospectiv

2004
Sequential supraclavicular brachial plexus block and intravenous regional anaesthesia for upper limb surgery.
    European journal of anaesthesiology, 2004, Volume: 21, Issue:9

    Topics: Adult; Anesthesia, Conduction; Anesthesia, Intravenous; Anesthetics, Intravenous; Anesthetics, Local

2004
The effect of ketamine and fentanyl in reducing the pain of diazepam injection.
    Middle East journal of anaesthesiology, 2004, Volume: 17, Issue:6

    Topics: Adolescent; Adult; Analgesics; Anesthetics, Intravenous; Diazepam; Double-Blind Method; Fentanyl; Hu

2004
Pharmacokinetics and tolerability of different doses of fentanyl following sublingual administration of a rapidly dissolving tablet to cancer patients: a new approach to treatment of incident pain.
    British journal of clinical pharmacology, 2005, Volume: 59, Issue:2

    Topics: Administration, Sublingual; Adult; Aged; Analgesics, Opioid; Analysis of Variance; Area Under Curve;

2005
Pharmacokinetics and tolerability of different doses of fentanyl following sublingual administration of a rapidly dissolving tablet to cancer patients: a new approach to treatment of incident pain.
    British journal of clinical pharmacology, 2005, Volume: 59, Issue:2

    Topics: Administration, Sublingual; Adult; Aged; Analgesics, Opioid; Analysis of Variance; Area Under Curve;

2005
Pharmacokinetics and tolerability of different doses of fentanyl following sublingual administration of a rapidly dissolving tablet to cancer patients: a new approach to treatment of incident pain.
    British journal of clinical pharmacology, 2005, Volume: 59, Issue:2

    Topics: Administration, Sublingual; Adult; Aged; Analgesics, Opioid; Analysis of Variance; Area Under Curve;

2005
Pharmacokinetics and tolerability of different doses of fentanyl following sublingual administration of a rapidly dissolving tablet to cancer patients: a new approach to treatment of incident pain.
    British journal of clinical pharmacology, 2005, Volume: 59, Issue:2

    Topics: Administration, Sublingual; Adult; Aged; Analgesics, Opioid; Analysis of Variance; Area Under Curve;

2005
Benefits of transdermal fentanyl in patients with rheumatoid arthritis or with osteoarthritis of the knee or hip: an open-label study to assess pain control.
    Current medical research and opinion, 2004, Volume: 20, Issue:12

    Topics: Administration, Cutaneous; Aged; Analgesics, Opioid; Arthritis, Rheumatoid; Female; Fentanyl; Humans

2004
The risk of cesarean delivery with neuraxial analgesia given early versus late in labor.
    The New England journal of medicine, 2005, Feb-17, Volume: 352, Issue:7

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Cesarean Section; Female; Fe

2005
The risk of cesarean delivery with neuraxial analgesia given early versus late in labor.
    The New England journal of medicine, 2005, Feb-17, Volume: 352, Issue:7

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Cesarean Section; Female; Fe

2005
The risk of cesarean delivery with neuraxial analgesia given early versus late in labor.
    The New England journal of medicine, 2005, Feb-17, Volume: 352, Issue:7

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Cesarean Section; Female; Fe

2005
The risk of cesarean delivery with neuraxial analgesia given early versus late in labor.
    The New England journal of medicine, 2005, Feb-17, Volume: 352, Issue:7

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Cesarean Section; Female; Fe

2005
The risk of cesarean delivery with neuraxial analgesia given early versus late in labor.
    The New England journal of medicine, 2005, Feb-17, Volume: 352, Issue:7

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Cesarean Section; Female; Fe

2005
The risk of cesarean delivery with neuraxial analgesia given early versus late in labor.
    The New England journal of medicine, 2005, Feb-17, Volume: 352, Issue:7

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Cesarean Section; Female; Fe

2005
The risk of cesarean delivery with neuraxial analgesia given early versus late in labor.
    The New England journal of medicine, 2005, Feb-17, Volume: 352, Issue:7

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Cesarean Section; Female; Fe

2005
The risk of cesarean delivery with neuraxial analgesia given early versus late in labor.
    The New England journal of medicine, 2005, Feb-17, Volume: 352, Issue:7

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Cesarean Section; Female; Fe

2005
The risk of cesarean delivery with neuraxial analgesia given early versus late in labor.
    The New England journal of medicine, 2005, Feb-17, Volume: 352, Issue:7

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Cesarean Section; Female; Fe

2005
The risk of cesarean delivery with neuraxial analgesia given early versus late in labor.
    The New England journal of medicine, 2005, Feb-17, Volume: 352, Issue:7

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Cesarean Section; Female; Fe

2005
The risk of cesarean delivery with neuraxial analgesia given early versus late in labor.
    The New England journal of medicine, 2005, Feb-17, Volume: 352, Issue:7

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Cesarean Section; Female; Fe

2005
The risk of cesarean delivery with neuraxial analgesia given early versus late in labor.
    The New England journal of medicine, 2005, Feb-17, Volume: 352, Issue:7

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Cesarean Section; Female; Fe

2005
The risk of cesarean delivery with neuraxial analgesia given early versus late in labor.
    The New England journal of medicine, 2005, Feb-17, Volume: 352, Issue:7

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Cesarean Section; Female; Fe

2005
The risk of cesarean delivery with neuraxial analgesia given early versus late in labor.
    The New England journal of medicine, 2005, Feb-17, Volume: 352, Issue:7

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Cesarean Section; Female; Fe

2005
The risk of cesarean delivery with neuraxial analgesia given early versus late in labor.
    The New England journal of medicine, 2005, Feb-17, Volume: 352, Issue:7

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Cesarean Section; Female; Fe

2005
The risk of cesarean delivery with neuraxial analgesia given early versus late in labor.
    The New England journal of medicine, 2005, Feb-17, Volume: 352, Issue:7

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Cesarean Section; Female; Fe

2005
The risk of cesarean delivery with neuraxial analgesia given early versus late in labor.
    The New England journal of medicine, 2005, Feb-17, Volume: 352, Issue:7

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Cesarean Section; Female; Fe

2005
The risk of cesarean delivery with neuraxial analgesia given early versus late in labor.
    The New England journal of medicine, 2005, Feb-17, Volume: 352, Issue:7

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Cesarean Section; Female; Fe

2005
The risk of cesarean delivery with neuraxial analgesia given early versus late in labor.
    The New England journal of medicine, 2005, Feb-17, Volume: 352, Issue:7

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Cesarean Section; Female; Fe

2005
The risk of cesarean delivery with neuraxial analgesia given early versus late in labor.
    The New England journal of medicine, 2005, Feb-17, Volume: 352, Issue:7

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Cesarean Section; Female; Fe

2005
The risk of cesarean delivery with neuraxial analgesia given early versus late in labor.
    The New England journal of medicine, 2005, Feb-17, Volume: 352, Issue:7

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Cesarean Section; Female; Fe

2005
The risk of cesarean delivery with neuraxial analgesia given early versus late in labor.
    The New England journal of medicine, 2005, Feb-17, Volume: 352, Issue:7

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Cesarean Section; Female; Fe

2005
The risk of cesarean delivery with neuraxial analgesia given early versus late in labor.
    The New England journal of medicine, 2005, Feb-17, Volume: 352, Issue:7

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Cesarean Section; Female; Fe

2005
The risk of cesarean delivery with neuraxial analgesia given early versus late in labor.
    The New England journal of medicine, 2005, Feb-17, Volume: 352, Issue:7

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Cesarean Section; Female; Fe

2005
The risk of cesarean delivery with neuraxial analgesia given early versus late in labor.
    The New England journal of medicine, 2005, Feb-17, Volume: 352, Issue:7

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Cesarean Section; Female; Fe

2005
A randomized, double-blind study comparing morphine with fentanyl in prehospital analgesia.
    The American journal of emergency medicine, 2005, Volume: 23, Issue:2

    Topics: Acute Disease; Adult; Analgesia; Analgesics, Opioid; Double-Blind Method; Emergency Medical Services

2005
[The use of transdermal fentanyl in chronic non-malignant pain].
    Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology, 2005, Volume: 17, Issue:1

    Topics: Activities of Daily Living; Administration, Cutaneous; Analgesics, Opioid; Chronic Disease; Female;

2005
Target-controlled infusion of remifentanil or fentanyl during extra-corporeal shock-wave lithotripsy.
    European journal of anaesthesiology, 2005, Volume: 22, Issue:1

    Topics: Adolescent; Adult; Analgesics, Opioid; Conscious Sedation; Drug Delivery Systems; Female; Fentanyl;

2005
Intra-cervical versus i.v. fentanyl for abortion.
    Human reproduction (Oxford, England), 2005, Volume: 20, Issue:7

    Topics: Abortion, Induced; Adolescent; Adult; Analgesics, Opioid; Anesthesia, Obstetrical; Cervix Uteri; Dou

2005
Transdermal fentanyl for the treatment of pain caused by osteoarthritis of the knee or hip: an open, multicentre study.
    BMC musculoskeletal disorders, 2005, Jun-15, Volume: 6

    Topics: Administration, Cutaneous; Analgesics, Opioid; Dose-Response Relationship, Drug; Fentanyl; Humans; M

2005
The comparative evaluation of gabapentin and carbamazepine for pain management in Guillain-Barré syndrome patients in the intensive care unit.
    Anesthesia and analgesia, 2005, Volume: 101, Issue:1

    Topics: Adult; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Carbamazepine; Conscious Sedation; Crit

2005
Effectiveness of eutectic mixture of local anesthetic cream and occlusive dressing with low dosage of fentanyl for pain control during shockwave lithotripsy.
    Journal of endourology, 2005, Volume: 19, Issue:5

    Topics: Administration, Topical; Aged; Analgesics, Opioid; Anesthetics, Local; Drug Therapy, Combination; Fe

2005
Intranasal fentanyl is an equivalent analgesic to oral morphine in paediatric burns patients for dressing changes: a randomised double blind crossover study.
    Burns : journal of the International Society for Burn Injuries, 2005, Volume: 31, Issue:7

    Topics: Administration, Intranasal; Administration, Oral; Analgesics, Opioid; Bandages; Burns; Child; Child,

2005
Intranasal fentanyl is an equivalent analgesic to oral morphine in paediatric burns patients for dressing changes: a randomised double blind crossover study.
    Burns : journal of the International Society for Burn Injuries, 2005, Volume: 31, Issue:7

    Topics: Administration, Intranasal; Administration, Oral; Analgesics, Opioid; Bandages; Burns; Child; Child,

2005
Intranasal fentanyl is an equivalent analgesic to oral morphine in paediatric burns patients for dressing changes: a randomised double blind crossover study.
    Burns : journal of the International Society for Burn Injuries, 2005, Volume: 31, Issue:7

    Topics: Administration, Intranasal; Administration, Oral; Analgesics, Opioid; Bandages; Burns; Child; Child,

2005
Intranasal fentanyl is an equivalent analgesic to oral morphine in paediatric burns patients for dressing changes: a randomised double blind crossover study.
    Burns : journal of the International Society for Burn Injuries, 2005, Volume: 31, Issue:7

    Topics: Administration, Intranasal; Administration, Oral; Analgesics, Opioid; Bandages; Burns; Child; Child,

2005
Opioid rotation from morphine to fentanyl in delirious cancer patients: an open-label trial.
    Journal of pain and symptom management, 2005, Volume: 30, Issue:1

    Topics: Aged; Analgesics, Opioid; Delirium; Dose-Response Relationship, Drug; Drug Administration Schedule;

2005
Inter- and intraindividual variabilities in pharmacokinetics of fentanyl after repeated 72-hour transdermal applications in cancer pain patients.
    Therapeutic drug monitoring, 2005, Volume: 27, Issue:4

    Topics: Acetaminophen; Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic;

2005
Analgesic efficacy of pre-operative etoricoxib for termination of pregnancy in an ambulatory centre.
    Singapore medical journal, 2005, Volume: 46, Issue:8

    Topics: Abortion, Induced; Administration, Oral; Adult; Analgesics, Opioid; Cyclooxygenase Inhibitors; Doubl

2005
Rapid switching between transdermal fentanyl and methadone in cancer patients.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Aug-01, Volume: 23, Issue:22

    Topics: Administration, Cutaneous; Analgesics, Opioid; Female; Fentanyl; Humans; Male; Methadone; Middle Age

2005
Switching from reservoir to matrix systems for the transdermal delivery of fentanyl: a prospective, multicenter pilot study in outpatients with chronic pain.
    Journal of pain and symptom management, 2005, Volume: 30, Issue:3

    Topics: Administration, Cutaneous; Aged; Analgesics, Opioid; Chronic Disease; Female; Fentanyl; Humans; Male

2005
Pain and anxiety during interventional radiologic procedures: effect of patients' state anxiety at baseline and modulation by nonpharmacologic analgesia adjuncts.
    Journal of vascular and interventional radiology : JVIR, 2005, Volume: 16, Issue:12

    Topics: Adaptation, Psychological; Aged; Analgesia, Patient-Controlled; Analysis of Variance; Anesthetics, I

2005
Prostate HDR radiation therapy: a comparative study evaluating the effectiveness of pain management with peripheral PCA vs. PCEA.
    Urologic nursing, 2006, Volume: 26, Issue:1

    Topics: Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Benchmar

2006
Transdermal fentanyl for improvement of pain and functioning in osteoarthritis: a randomized, placebo-controlled trial.
    Arthritis and rheumatism, 2006, Volume: 54, Issue:6

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Female; Fentanyl; Hum

2006
[Individual aspects of the quality of life of patients with chronic pain. Observational study of treatment with fentanyl-TTS].
    MMW Fortschritte der Medizin, 2005, Apr-07, Volume: 147 Suppl 1

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Child; Ch

2005
Opioid-induced respiratory effects: new data on buprenorphine.
    Palliative medicine, 2006, Volume: 20 Suppl 1

    Topics: Analgesics, Opioid; Apnea; Buprenorphine; Dose-Response Relationship, Drug; Double-Blind Method; Fen

2006
Relative bioavailability of the fentanyl effervescent buccal tablet (FEBT) 1,080 pg versus oral transmucosal fentanyl citrate 1,600 pg and dose proportionality of FEBT 270 to 1,300 microg: a single-dose, randomized, open-label, three-period study in healt
    Clinical therapeutics, 2006, Volume: 28, Issue:5

    Topics: Administration, Buccal; Administration, Oral; Adult; Algorithms; Analgesics, Opioid; Area Under Curv

2006
A Phase III study to assess the clinical utility of low-dose fentanyl transdermal system in patients with chronic nonmalignant pain.
    Current medical research and opinion, 2006, Volume: 22, Issue:8

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Chronic D

2006
Differential sensitivity of three experimental pain models in detecting the analgesic effects of transdermal fentanyl and buprenorphine.
    Pain, 2006, Dec-15, Volume: 126, Issue:1-3

    Topics: Administration, Cutaneous; Adult; Analgesics, Opioid; Buprenorphine; Cold Temperature; Cross-Over St

2006
Effect of local anesthesia and intravenous sedation on pain perception and vasovagal reactions during femoral arterial sheath removal after percutaneous coronary intervention.
    International journal of cardiology, 2007, Apr-04, Volume: 116, Issue:3

    Topics: Aged; Anesthetics, Local; Angioplasty, Balloon, Coronary; Bradycardia; Cardiovascular Diseases; Cons

2007
Injectate temperature and discomfort during epidural injection.
    International journal of obstetric anesthesia, 2006, Volume: 15, Issue:4

    Topics: Anesthetics, Local; Bupivacaine; Double-Blind Method; Drug Storage; Female; Fentanyl; Humans; Inject

2006
Etomidate versus midazolam for procedural sedation in pediatric outpatients: a randomized controlled trial.
    Annals of emergency medicine, 2006, Volume: 48, Issue:4

    Topics: Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child, Preschool; Consumer Behavior

2006
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department.
    Annals of emergency medicine, 2007, Volume: 49, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Dose-Response Rela

2007
Differential effect of intravenous S-ketamine and fentanyl on atypical odontalgia and capsaicin-evoked pain.
    Pain, 2007, Volume: 129, Issue:1-2

    Topics: Adult; Analgesics; Analysis of Variance; Area Under Curve; Capsaicin; Case-Control Studies; Double-B

2007
Safety and efficacy of transdermal fentanyl in patients with cancer pain: phase IV, Turkish oncology group trial.
    European journal of cancer care, 2007, Volume: 16, Issue:1

    Topics: Administration, Cutaneous; Adolescent; Adult; Analgesics, Opioid; Female; Fentanyl; Humans; Male; Mi

2007
Hemodynamic stability during labor and delivery with continuous epidural infusion.
    The Journal of the American Osteopathic Association, 2006, Volume: 106, Issue:12

    Topics: Adult; Amides; Analgesia, Obstetrical; Anesthesia, Epidural; Anesthetics, Intravenous; Anesthetics,

2006
A double-blind comparison of a supplemental interligamentary injection of fentanyl and mepivacaine with 1:200,000 epinephrine for irreversible pulpitis.
    Journal of pain and symptom management, 2007, Volume: 33, Issue:2

    Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Double-Blind Method; Drug Therapy, Combination; Epine

2007
[Hyperbaric bupivacaine: a randomized double-blind trial of different doses with or without fentanyl for cesarean section under spinal anesthesia].
    Revista espanola de anestesiologia y reanimacion, 2007, Volume: 54, Issue:1

    Topics: Adult; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Cesarean Section; Dose-Response Relation

2007
Impact of breakthrough pain on quality of life in patients with chronic, noncancer pain: patient perceptions and effect of treatment with oral transmucosal fentanyl citrate (OTFC, ACTIQ).
    Pain medicine (Malden, Mass.), 2007, Volume: 8, Issue:3

    Topics: Adult; Affect; Aged; Analgesics, Opioid; Chronic Disease; Female; Fentanyl; Humans; Male; Middle Age

2007
Oral transmucosal fentanyl citrate versus placebo for painful dressing changes: a crossover trial.
    Journal of wound care, 2007, Volume: 16, Issue:3

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthetics, Combined; Ban

2007
Comparison of analgesic efficacy of fentanyl and sufentanil for chest tube removal after cardiac surgery.
    Annals of cardiac anaesthesia, 2007, Volume: 10, Issue:1

    Topics: Adult; Aged; Analgesics, Opioid; Analysis of Variance; Blood Pressure; Cardiac Surgical Procedures;

2007
Transmucosal fentanyl vs intravenous morphine in doses proportional to basal opioid regimen for episodic-breakthrough pain.
    British journal of cancer, 2007, Jun-18, Volume: 96, Issue:12

    Topics: Administration, Oral; Adolescent; Adult; Analgesics, Opioid; Child; Child, Preschool; Cross-Over Stu

2007
Time-course of change in [11C]carfentanil and [11C]raclopride binding potential after a nonpharmacological challenge.
    Synapse (New York, N.Y.), 2007, Volume: 61, Issue:9

    Topics: Adult; Analgesics, Opioid; Binding, Competitive; Brain; Brain Mapping; Carbon Radioisotopes; Dopamin

2007
Fentanyl buccal tablet for the relief of breakthrough pain in opioid-tolerant adult patients with chronic neuropathic pain: a multicenter, randomized, double-blind, placebo-controlled study.
    Clinical therapeutics, 2007, Volume: 29, Issue:4

    Topics: Administration, Buccal; Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Disease; Double-Blind M

2007
Impact of an information video before colonoscopy on patient satisfaction and anxiety - a randomized trial.
    Endoscopy, 2007, Volume: 39, Issue:8

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anxiety; Audiovisual Aids; Colonoscopy; Con

2007
Absorption of fentanyl from fentanyl buccal tablet in cancer patients with or without oral mucositis: a pilot study.
    Clinical drug investigation, 2007, Volume: 27, Issue:9

    Topics: Absorption; Administration, Buccal; Adult; Aged; Analgesics, Opioid; Antineoplastic Agents; Female;

2007
A randomized clinical trial of oral transmucosal fentanyl citrate versus intravenous morphine sulfate for initial control of pain in children with extremity injuries.
    Pediatric emergency care, 2007, Volume: 23, Issue:8

    Topics: Administration, Oral; Adolescent; Analgesics, Opioid; Arm Injuries; Child; Female; Fentanyl; Humans;

2007
Randomized clinical trial of nebulized fentanyl citrate versus i.v. fentanyl citrate in children presenting to the emergency department with acute pain.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2007, Volume: 14, Issue:10

    Topics: Acute Disease; Administration, Inhalation; Adolescent; Analgesics, Opioid; Child; Child, Preschool;

2007
A randomized controlled trial of intranasal fentanyl vs intravenous morphine for analgesia in the prehospital setting.
    The American journal of emergency medicine, 2007, Volume: 25, Issue:8

    Topics: Administration, Intranasal; Adolescent; Adult; Aged; Analgesics, Opioid; Emergency Medical Services;

2007
Improved cancer pain treatment using combined fentanyl-TTS and tramadol.
    Pain practice : the official journal of World Institute of Pain, 2007, Volume: 7, Issue:4

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics, Opioid;

2007
Effect of narcotic pretreatment on pain after rocuronium injection: a randomized, double-blind controlled comparison with lidocaine.
    Journal of anesthesia, 2007, Volume: 21, Issue:4

    Topics: Adult; Androstanols; Double-Blind Method; Female; Fentanyl; Humans; Injections, Intravenous; Lidocai

2007
Analgesia for retrobulbar block--comparison of remifentanil, alfentanil and fentanyl.
    Middle East journal of anaesthesiology, 2007, Volume: 19, Issue:3

    Topics: Aged; Alfentanil; Analgesics, Opioid; Anesthesia, Spinal; Blood Pressure; Double-Blind Method; Femal

2007
Comparison of sciatic psoas compartment block and sciatic femoral 3-in-1 block for knee arthroscopy.
    Journal of clinical anesthesia, 2007, Volume: 19, Issue:8

    Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Arthroscopy; Bupivacaine; Elective Surgical Pro

2007
Propofol-ketamine vs propofol-fentanyl combinations for deep sedation and analgesia in pediatric patients undergoing burn dressing changes.
    Paediatric anaesthesia, 2008, Volume: 18, Issue:1

    Topics: Analgesia; Anesthetics, Dissociative; Anesthetics, Intravenous; Bandages; Blood Pressure; Burns; Chi

2008
Placebo and nocebo effects are defined by opposite opioid and dopaminergic responses.
    Archives of general psychiatry, 2008, Volume: 65, Issue:2

    Topics: Adult; Analgesics; Brain; Brain Mapping; Carbon Radioisotopes; Culture; Female; Fentanyl; Humans; Im

2008
Analgesia during extracorporeal shockwave lithotripsy: fentanyl citrate versus parecoxib sodium.
    Journal of endourology, 2008, Volume: 22, Issue:4

    Topics: Adult; Aged; Analgesics, Opioid; Cyclooxygenase Inhibitors; Female; Fentanyl; Humans; Isoxazoles; Li

2008
Comparison of the effectiveness of pretreatment by fentanyl and remifentanil on rocuronium induced injection pain.
    Saudi medical journal, 2008, Volume: 29, Issue:3

    Topics: Adult; Aged; Analgesics, Opioid; Androstanols; Double-Blind Method; Female; Fentanyl; Humans; Inject

2008
Determination of fentanyl in sweat and hair of a patient using transdermal patches.
    Journal of analytical toxicology, 2008, Volume: 32, Issue:3

    Topics: Administration, Cutaneous; Adult; Analgesics, Opioid; Chromatography, Liquid; Fentanyl; Hair; Humans

2008
Pharmacokinetics, efficacy, and tolerability of fentanyl following intranasal versus intravenous administration in adults undergoing third-molar extraction: a randomized, double-blind, double-dummy, two-way, crossover study.
    Clinical therapeutics, 2008, Volume: 30, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Adult; Anesthetics, Intravenous; Cross-Over Studies; Dose

2008
Efficacy, safety and pharmacokinetic study of a novel fentanyl-containing matrix transdermal patch system in Japanese patients with cancer pain.
    Clinical drug investigation, 2008, Volume: 28, Issue:5

    Topics: Administration, Cutaneous; Adult; Aged; Analgesics, Opioid; Endpoint Determination; Female; Fentanyl

2008
Alfentanil in minor gynaecological surgery: use with etomidate and a comparison with halothane.
    Anaesthesia, 1984, Volume: 39, Issue:8

    Topics: Adjuvants, Anesthesia; Adolescent; Adult; Alfentanil; Ambulatory Surgical Procedures; Analgesics, Op

1984
Double-blind placebo-controlled trial of baclofen, alone and in combination, in patients undergoing voluntary abortion.
    Clinical therapeutics, 1984, Volume: 6, Issue:6

    Topics: Abortion, Induced; Adolescent; Adult; Baclofen; Clinical Trials as Topic; Diazepam; Dilatation and C

1984
Effect of fentanyl and naloxone on the P300 auditory potential.
    Neuropharmacology, 1984, Volume: 23, Issue:8

    Topics: Adult; Electroencephalography; Evoked Potentials, Auditory; Female; Fentanyl; Humans; Male; Naloxone

1984
Pain and myoclonus during induction with etomidate. A double-blind, controlled evaluation of the influence of droperidol and fentanyl.
    Acta anaesthesiologica Belgica, 1981, Volume: 32, Issue:2

    Topics: Adolescent; Adult; Aged; Anesthesia; Clinical Trials as Topic; Diazepam; Double-Blind Method; Droper

1981
Masseter inhibitory periods and sensations evoked by electrical tooth pulp stimulation.
    Pain, 1981, Volume: 10, Issue:1

    Topics: Adolescent; Adult; Dental Pulp; Electric Stimulation; Electromyography; Female; Fentanyl; Humans; Ma

1981
[Epidural application of opiates in chronic pain due to malignoma (author's transl)].
    Anasthesie, Intensivtherapie, Notfallmedizin, 1981, Volume: 16, Issue:5

    Topics: Adult; Aged; Catheterization; Female; Fentanyl; Humans; Male; Meperidine; Middle Aged; Morphine; Nar

1981
[Comparison between the analgesic effects of fentanyl and morphine in conscious man (author's transl)].
    Anesthesie, analgesie, reanimation, 1980, Volume: 37, Issue:5-6

    Topics: Female; Fentanyl; Humans; Injections, Intramuscular; Male; Morphine; Pain; Time Factors

1980
Pain sensation in transurethral microwave thermotherapy for benign prostatic hyperplasia: the rationale for prophylactic sedation.
    European urology, 1994, Volume: 25, Issue:1

    Topics: Analgesia; Conscious Sedation; Diathermy; Fentanyl; Humans; Male; Microwaves; Oxazepam; Pain; Prospe

1994
Intravenous regional anesthesia using lidocaine and ketorolac.
    Anesthesia and analgesia, 1995, Volume: 81, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthesia, Conduction; Anesthesia, Intravenous; Anti-Infla

1995
Transdermal fentanyl: clinical development in the United States.
    Anti-cancer drugs, 1995, Volume: 6 Suppl 3

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Dose-Response Relationship, Drug; Drug

1995
Transdermal fentanyl: a new step on the therapeutic ladder.
    Anti-cancer drugs, 1995, Volume: 6 Suppl 3

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Aged, 80 and over; Ambulatory Care; Bl

1995
Transdermal fentanyl in combination with initial intravenous dose titration by patient-controlled analgesia.
    Anti-cancer drugs, 1995, Volume: 6 Suppl 3

    Topics: Administration, Cutaneous; Analgesia, Patient-Controlled; Analgesics; Constipation; Dose-Response Re

1995
The use of oral transmucosal fentanyl citrate for painful procedures in children.
    Pediatrics, 1995, Volume: 95, Issue:3

    Topics: Administration, Buccal; Adolescent; Bone Marrow Examination; Candy; Child; Child, Preschool; Conscio

1995
A dose-response study of the effects of intravenous midazolam on cold pressor-induced pain.
    Anesthesia and analgesia, 1995, Volume: 80, Issue:3

    Topics: Adult; Affect; Cold Temperature; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fent

1995
An assessment of prilocaine as a topical anaesthetic agent for fibreoptic bronchoscopy in comparison with lidocaine.
    Acta anaesthesiologica Scandinavica, 1994, Volume: 38, Issue:5

    Topics: Adult; Aged; Anesthetics; Anesthetics, Local; Bronchoscopy; Conscious Sedation; Double-Blind Method;

1994
Double-blind comparison of intravenous butorphanol (Stadol) and fentanyl (Sublimaze) for analgesia during labor.
    American journal of obstetrics and gynecology, 1994, Volume: 171, Issue:4

    Topics: Adolescent; Adult; Analgesia, Obstetrical; Butorphanol; Double-Blind Method; Female; Fentanyl; Human

1994
Oral transmucosal fentanyl citrate for premedication of children undergoing laceration repair.
    Annals of emergency medicine, 1994, Volume: 24, Issue:6

    Topics: Administration, Oral; Anxiety; Child; Child, Preschool; Conscious Sedation; Emergencies; Fentanyl; H

1994
Is paracervical block anesthesia for oocyte retrieval effective?
    Fertility and sterility, 1994, Volume: 62, Issue:1

    Topics: Adult; Anesthesia, Spinal; Double-Blind Method; Female; Fentanyl; Humans; Multivariate Analysis; Nec

1994
Transdermal fentanyl in uncontrolled cancer pain: titration on a day-to-day basis as a procedure for safe and effective dose finding--a pilot study in 20 patients.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 1994, Volume: 2, Issue:2

    Topics: Administration, Cutaneous; Administration, Oral; Fentanyl; Gastrointestinal Motility; Humans; Morphi

1994
Determinants of catecholamine and cortisol responses to lower extremity revascularization. The PIRAT Study Group.
    Anesthesiology, 1993, Volume: 79, Issue:6

    Topics: Adult; Aged; Anesthesia, Epidural; Anesthesia, General; Catecholamines; Female; Fentanyl; Humans; Hy

1993
Effect of intravenous diclofenac on pain and recovery profile after day-case laparoscopy.
    European journal of anaesthesiology, 1993, Volume: 10, Issue:2

    Topics: Acetaminophen; Adult; Ambulatory Care; Diclofenac; Double-Blind Method; Female; Fentanyl; Humans; In

1993
The effects of electrical stimulation at different frequencies on perception and pain in human volunteers: epidural versus intravenous administration of fentanyl.
    Anesthesia and analgesia, 1996, Volume: 82, Issue:1

    Topics: Adult; Analgesia; Analgesics, Opioid; Combined Modality Therapy; Cross-Over Studies; Double-Blind Me

1996
Direct conversion from oral morphine to transdermal fentanyl: a multicenter study in patients with cancer pain.
    Pain, 1996, Volume: 64, Issue:3

    Topics: Administration, Cutaneous; Adult; Aged; Analgesics, Opioid; Female; Fentanyl; Humans; Male; Middle A

1996
Comparison of oral transmucosal fentanyl citrate and intramuscular meperidine, promethazine, and chlorpromazine for conscious sedation of children undergoing laceration repair.
    Annals of emergency medicine, 1996, Volume: 28, Issue:4

    Topics: Administration, Oral; Analgesics, Opioid; Child, Preschool; Chlorpromazine; Dermatologic Surgical Pr

1996
A comparison of morphine, pethidine and fentanyl in the postsurgical patient-controlled analgesia environment.
    Pain, 1996, Volume: 64, Issue:1

    Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Double-Blind Method; Female; Fentany

1996
Transdermal fentanyl in the management of cancer pain in ambulatory patients: an open-label pilot study.
    Journal of pain and symptom management, 1996, Volume: 12, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Ambulatory Care; Analgesics, Opioid; Fentanyl; Humans; Middle Aged;

1996
Reduction of propofol pain--fentanyl vs lidocaine.
    Middle East journal of anaesthesiology, 1996, Volume: 13, Issue:6

    Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Anesthetics, Intravenous; Anesthetics, Local; Female; F

1996
Conscious sedation for interventional neuroradiology: a comparison of midazolam and propofol infusion.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1997, Volume: 44, Issue:1

    Topics: Adult; Anesthetics, Intravenous; Anxiety; Attitude of Health Personnel; Cerebrovascular Disorders; C

1997
Regional brain activity changes associated with fentanyl analgesia elucidated by positron emission tomography.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:1

    Topics: Adult; Analgesics, Opioid; Brain; Cerebrovascular Circulation; Female; Fentanyl; Hot Temperature; Hu

1997
Analgesia following arthroscopy--a comparison of intra-articular morphine, pethidine and fentanyl.
    Acta anaesthesiologica Scandinavica, 1997, Volume: 41, Issue:1 Pt 1

    Topics: Acetaminophen; Adult; Alfentanil; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General;

1997
Randomised double-blind active-placebo-controlled crossover trial of intravenous fentanyl in neuropathic pain.
    Lancet (London, England), 1997, Mar-15, Volume: 349, Issue:9054

    Topics: Adult; Aged; Analgesics, Opioid; Cross-Over Studies; Diazepam; Double-Blind Method; Female; Fentanyl

1997
The antinociceptive effect of epidural lignocaine and fentanyl during lithotripsy.
    Anaesthesia and intensive care, 1997, Volume: 25, Issue:1

    Topics: Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Dose-Response Relationship, Drug; Doubl

1997
A comparison of three regional anaesthesia techniques for outpatient knee arthroscopy.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1997, Volume: 44, Issue:4

    Topics: Adult; Ambulatory Surgical Procedures; Analgesics, Opioid; Anesthesia, Conduction; Anesthetics, Loca

1997
Propofol patient-controlled sedation during hip or knee arthroplasty in elderly patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1997, Volume: 44, Issue:4

    Topics: Adjuvants, Anesthesia; Aged; Anesthesia, Conduction; Anxiety; Arthroplasty; Cognition; Conscious Sed

1997
Transdermal fentanyl for severe cancer-related pain.
    Palliative medicine, 1997, Volume: 11, Issue:3

    Topics: Administration, Cutaneous; Adult; Aged; Analgesics, Opioid; Female; Fentanyl; Humans; Male; Middle A

1997
The value of end-tidal CO2 monitoring when comparing three methods of conscious sedation for children undergoing painful procedures in the emergency department.
    Pediatric emergency care, 1997, Volume: 13, Issue:3

    Topics: Capnography; Carbon Dioxide; Child; Chlorpromazine; Conscious Sedation; Drug Combinations; Emergency

1997
The analgesic effect of fentanyl, morphine, meperidine, and lidocaine in the peripheral veins: a comparative study.
    Anesthesia and analgesia, 1998, Volume: 86, Issue:2

    Topics: Adult; Analgesics; Double-Blind Method; Female; Fentanyl; Humans; Injections, Intravenous; Lidocaine

1998
Endogenous morphine levels increase following cardiac surgery as part of the antiinflammatory response?
    International journal of cardiology, 1997, Dec-19, Volume: 62, Issue:3

    Topics: Adult; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, General; Coronary Artery Bypass; Fentan

1997
Consequences of inadequate analgesia during painful procedures in children.
    Archives of pediatrics & adolescent medicine, 1998, Volume: 152, Issue:2

    Topics: Administration, Oral; Adolescent; Analgesics, Opioid; Analysis of Variance; Anxiety; Bone Marrow Exa

1998
Consequences of inadequate analgesia during painful procedures in children.
    Archives of pediatrics & adolescent medicine, 1998, Volume: 152, Issue:2

    Topics: Administration, Oral; Adolescent; Analgesics, Opioid; Analysis of Variance; Anxiety; Bone Marrow Exa

1998
Consequences of inadequate analgesia during painful procedures in children.
    Archives of pediatrics & adolescent medicine, 1998, Volume: 152, Issue:2

    Topics: Administration, Oral; Adolescent; Analgesics, Opioid; Analysis of Variance; Anxiety; Bone Marrow Exa

1998
Consequences of inadequate analgesia during painful procedures in children.
    Archives of pediatrics & adolescent medicine, 1998, Volume: 152, Issue:2

    Topics: Administration, Oral; Adolescent; Analgesics, Opioid; Analysis of Variance; Anxiety; Bone Marrow Exa

1998
Consequences of inadequate analgesia during painful procedures in children.
    Archives of pediatrics & adolescent medicine, 1998, Volume: 152, Issue:2

    Topics: Administration, Oral; Adolescent; Analgesics, Opioid; Analysis of Variance; Anxiety; Bone Marrow Exa

1998
Consequences of inadequate analgesia during painful procedures in children.
    Archives of pediatrics & adolescent medicine, 1998, Volume: 152, Issue:2

    Topics: Administration, Oral; Adolescent; Analgesics, Opioid; Analysis of Variance; Anxiety; Bone Marrow Exa

1998
Consequences of inadequate analgesia during painful procedures in children.
    Archives of pediatrics & adolescent medicine, 1998, Volume: 152, Issue:2

    Topics: Administration, Oral; Adolescent; Analgesics, Opioid; Analysis of Variance; Anxiety; Bone Marrow Exa

1998
Consequences of inadequate analgesia during painful procedures in children.
    Archives of pediatrics & adolescent medicine, 1998, Volume: 152, Issue:2

    Topics: Administration, Oral; Adolescent; Analgesics, Opioid; Analysis of Variance; Anxiety; Bone Marrow Exa

1998
Consequences of inadequate analgesia during painful procedures in children.
    Archives of pediatrics & adolescent medicine, 1998, Volume: 152, Issue:2

    Topics: Administration, Oral; Adolescent; Analgesics, Opioid; Analysis of Variance; Anxiety; Bone Marrow Exa

1998
Quality of life and cancer pain: satisfaction and side effects with transdermal fentanyl versus oral morphine.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:4

    Topics: Administration, Cutaneous; Aged; Analgesics, Opioid; Cross-Sectional Studies; Delayed-Action Prepara

1998
Comparison of intravenous retention of fentanyl and lidocaine on local analgesia in propofol injection pain.
    Acta anaesthesiologica Sinica, 1997, Volume: 35, Issue:4

    Topics: Adolescent; Adult; Aged; Analgesia; Analgesics, Opioid; Anesthetics, Intravenous; Anesthetics, Local

1997
Oral transmucosal fentanyl citrate: randomized, double-blinded, placebo-controlled trial for treatment of breakthrough pain in cancer patients.
    Journal of the National Cancer Institute, 1998, Apr-15, Volume: 90, Issue:8

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Double-Blind Method; Femal

1998
Long-term treatment of cancer pain with transdermal fentanyl.
    Journal of pain and symptom management, 1998, Volume: 15, Issue:3

    Topics: Administration, Cutaneous; Adult; Aged; Analgesics, Opioid; Female; Fentanyl; Humans; Male; Middle A

1998
Physiological, hormonal, and behavioral responses to a single fentanyl dose in intubated and ventilated preterm neonates.
    The Journal of pediatrics, 1998, Volume: 132, Issue:6

    Topics: Analgesia; Analgesics, Opioid; Blood Glucose; Catheterization, Central Venous; Double-Blind Method;

1998
Effect of epidural fentanyl on neonatal respiration.
    Anesthesiology, 1998, Volume: 89, Issue:1

    Topics: Adult; Analgesics, Opioid; Female; Fentanyl; Humans; Infant, Newborn; Injections, Spinal; Labor, Obs

1998
[Pain-free injection of propofol].
    Masui. The Japanese journal of anesthesiology, 1998, Volume: 47, Issue:7

    Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Female; Fentanyl; Humans; Hypothermia, Induced;

1998
A clinical evaluation of transdermal therapeutic system fentanyl for the treatment of cancer pain.
    Journal of pain and symptom management, 1998, Volume: 16, Issue:2

    Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Disease; Evaluation

1998
[Controlled analgesia in a burn patient: fentanyl sparing effect of clonidine].
    Annales francaises d'anesthesie et de reanimation, 1998, Volume: 17, Issue:1

    Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Analgesia, Patient-Controlled; Burns; Clonidine; Doubl

1998
[Reduction of pain on injection of propofol: a comparison of fentanyl with lidocaine].
    Masui. The Japanese journal of anesthesiology, 1998, Volume: 47, Issue:8

    Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Intravenous; Anesthetics, Local; Drug Combinations; Fe

1998
Comparison of fentanyl/midazolam with ketamine/midazolam for pediatric orthopedic emergencies.
    Pediatrics, 1998, Volume: 102, Issue:4 Pt 1

    Topics: Adolescent; Analgesics, Opioid; Anesthetics, Dissociative; Anti-Anxiety Agents; Anxiety; Child; Chil

1998
Comparison of fentanyl/midazolam with ketamine/midazolam for pediatric orthopedic emergencies.
    Pediatrics, 1998, Volume: 102, Issue:4 Pt 1

    Topics: Adolescent; Analgesics, Opioid; Anesthetics, Dissociative; Anti-Anxiety Agents; Anxiety; Child; Chil

1998
Comparison of fentanyl/midazolam with ketamine/midazolam for pediatric orthopedic emergencies.
    Pediatrics, 1998, Volume: 102, Issue:4 Pt 1

    Topics: Adolescent; Analgesics, Opioid; Anesthetics, Dissociative; Anti-Anxiety Agents; Anxiety; Child; Chil

1998
Comparison of fentanyl/midazolam with ketamine/midazolam for pediatric orthopedic emergencies.
    Pediatrics, 1998, Volume: 102, Issue:4 Pt 1

    Topics: Adolescent; Analgesics, Opioid; Anesthetics, Dissociative; Anti-Anxiety Agents; Anxiety; Child; Chil

1998
Comparison of fentanyl/midazolam with ketamine/midazolam for pediatric orthopedic emergencies.
    Pediatrics, 1998, Volume: 102, Issue:4 Pt 1

    Topics: Adolescent; Analgesics, Opioid; Anesthetics, Dissociative; Anti-Anxiety Agents; Anxiety; Child; Chil

1998
Comparison of fentanyl/midazolam with ketamine/midazolam for pediatric orthopedic emergencies.
    Pediatrics, 1998, Volume: 102, Issue:4 Pt 1

    Topics: Adolescent; Analgesics, Opioid; Anesthetics, Dissociative; Anti-Anxiety Agents; Anxiety; Child; Chil

1998
Comparison of fentanyl/midazolam with ketamine/midazolam for pediatric orthopedic emergencies.
    Pediatrics, 1998, Volume: 102, Issue:4 Pt 1

    Topics: Adolescent; Analgesics, Opioid; Anesthetics, Dissociative; Anti-Anxiety Agents; Anxiety; Child; Chil

1998
Comparison of fentanyl/midazolam with ketamine/midazolam for pediatric orthopedic emergencies.
    Pediatrics, 1998, Volume: 102, Issue:4 Pt 1

    Topics: Adolescent; Analgesics, Opioid; Anesthetics, Dissociative; Anti-Anxiety Agents; Anxiety; Child; Chil

1998
Comparison of fentanyl/midazolam with ketamine/midazolam for pediatric orthopedic emergencies.
    Pediatrics, 1998, Volume: 102, Issue:4 Pt 1

    Topics: Adolescent; Analgesics, Opioid; Anesthetics, Dissociative; Anti-Anxiety Agents; Anxiety; Child; Chil

1998
Dose-titration, multicenter study of oral transmucosal fentanyl citrate for the treatment of breakthrough pain in cancer patients using transdermal fentanyl for persistent pain.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:10

    Topics: Administration, Buccal; Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Opioi

1998
Determination of the analgesic dose-response relationship for epidural fentanyl and sufentanil with bupivacaine 0.125% in laboring patients.
    Journal of clinical anesthesia, 1998, Volume: 10, Issue:8

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Analysis of Variance; Anesth

1998
Advantages of fentanyl over morphine in analgesia for ventilated newborn infants after birth: A randomized trial.
    The Journal of pediatrics, 1999, Volume: 134, Issue:2

    Topics: Analgesics, Opioid; beta-Endorphin; Catecholamines; Double-Blind Method; Fentanyl; Humans; Infant, N

1999
Comparison of three solutions of ropivacaine/fentanyl for postoperative patient-controlled epidural analgesia.
    Anesthesiology, 1999, Volume: 90, Issue:3

    Topics: Amides; Analgesics, Opioid; Anesthesia, Epidural; Anesthetics, Local; Double-Blind Method; Fentanyl;

1999
Midazolam/ketamine sedative combination compared with fentanyl/propofol/isoflurane anaesthesia for oocyte retrieval.
    Human reproduction (Oxford, England), 1999, Volume: 14, Issue:7

    Topics: Adult; Anesthesia, General; Anesthetics; Female; Fentanyl; Humans; Hypnotics and Sedatives; Isoflura

1999
[Effects of speed of injection on anesthesia induction with propofol and fentanyl].
    Masui. The Japanese journal of anesthesiology, 1999, Volume: 48, Issue:8

    Topics: Aged; Anesthesia, Intravenous; Anesthetics, Combined; Anesthetics, Intravenous; Blood Pressure; Drug

1999
A comparison of subcutaneous morphine and fentanyl in hospice cancer patients.
    Journal of pain and symptom management, 1999, Volume: 18, Issue:2

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Female; Fentanyl; Hospice Care; Humans; Injections, Sub

1999
Effect of intrathecal fentanyl dose on the duration of labor analgesia.
    AANA journal, 1999, Volume: 67, Issue:3

    Topics: Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Spinal; Female; Fentanyl; Humans; Middle Age

1999
Combined spinal-epidural analgesia in labour: comparison of two doses of intrathecal bupivacaine with fentanyl.
    British journal of anaesthesia, 1999, Volume: 83, Issue:6

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthetics, Local; Bupivaca

1999
Effects of 3 analgesic regimens on the perception of pain after removal of femoral artery sheaths.
    American journal of critical care : an official publication, American Association of Critical-Care Nurses, 2000, Volume: 9, Issue:2

    Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Local; Angioplasty, Balloon, Coronary; Attitude to Hea

2000
Comparison of combined spinal-epidural and low dose epidural for labour analgesia.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2000, Volume: 47, Issue:3

    Topics: Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthetics, Local; Buffers; Bupiva

2000
Combined spinal epidural for labour analgesia--duration, efficacy and side effects of adding sufentanil or fentanyl to bupivacaine intrathecally vs plain bupivacaine.
    Singapore medical journal, 1999, Volume: 40, Issue:10

    Topics: Adjuvants, Anesthesia; Adult; Anesthesia, Epidural; Anesthetics, Local; Bupivacaine; Female; Fentany

1999
Transdermal fentanyl in opioid-naive cancer pain patients: an open trial using transdermal fentanyl for the treatment of chronic cancer pain in opioid-naive patients and a group using codeine.
    Journal of pain and symptom management, 2000, Volume: 19, Issue:3

    Topics: Administration, Cutaneous; Analgesics, Opioid; Codeine; Fentanyl; Humans; Neoplasms; Pain

2000
Constipation and the use of laxatives: a comparison between transdermal fentanyl and oral morphine.
    Palliative medicine, 2000, Volume: 14, Issue:2

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics, Opioid;

2000
Selective opiate modulation of nociceptive processing in the human brain.
    Journal of neurophysiology, 2000, Volume: 84, Issue:1

    Topics: Adolescent; Adult; Analgesics, Opioid; Autonomic Nervous System; Cerebrovascular Circulation; Cold T

2000
[Research from the Palliative Care Department in Poznań on treatment of neoplasm pain with Durogesic (transdermal fentanyl)].
    Przeglad lekarski, 2000, Volume: 57, Issue:1

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics, Opioid;

2000
Comparison of fentanyl and droperidol mixture (neuroleptanalgesia II) with morphine on clinical outcomes in unstable angina patients.
    Cardiovascular drugs and therapy, 2000, Volume: 14, Issue:3

    Topics: Analgesics, Opioid; Angina, Unstable; Chromatography, Gas; Dopamine Antagonists; Droperidol; Drug Th

2000
A randomised controlled trial of intravenous versus inhalational analgesia during outpatient oocyte recovery.
    Anaesthesia, 2000, Volume: 55, Issue:8

    Topics: Administration, Inhalation; Adult; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Inhalation

2000
Demographic and therapeutic determinants of pain reactivity in very low birth weight neonates at 32 Weeks' postconceptional Age.
    Pediatrics, 2001, Volume: 107, Issue:1

    Topics: Blood Specimen Collection; Cohort Studies; Dexamethasone; Electrocardiography; Facial Expression; Fe

2001
Randomised crossover trial of transdermal fentanyl and sustained release oral morphine for treating chronic non-cancer pain.
    BMJ (Clinical research ed.), 2001, May-12, Volume: 322, Issue:7295

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Disease; Cros

2001
Long-term observations of patients receiving transdermal fentanyl after a randomized trial.
    Journal of pain and symptom management, 2001, Volume: 21, Issue:5

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Female; F

2001
Regional mu opioid receptor regulation of sensory and affective dimensions of pain.
    Science (New York, N.Y.), 2001, Jul-13, Volume: 293, Issue:5528

    Topics: Adult; Amygdala; Analgesics, Opioid; Brain; Brain Mapping; Female; Fentanyl; Humans; Magnetic Resona

2001
Regional mu opioid receptor regulation of sensory and affective dimensions of pain.
    Science (New York, N.Y.), 2001, Jul-13, Volume: 293, Issue:5528

    Topics: Adult; Amygdala; Analgesics, Opioid; Brain; Brain Mapping; Female; Fentanyl; Humans; Magnetic Resona

2001
Regional mu opioid receptor regulation of sensory and affective dimensions of pain.
    Science (New York, N.Y.), 2001, Jul-13, Volume: 293, Issue:5528

    Topics: Adult; Amygdala; Analgesics, Opioid; Brain; Brain Mapping; Female; Fentanyl; Humans; Magnetic Resona

2001
Regional mu opioid receptor regulation of sensory and affective dimensions of pain.
    Science (New York, N.Y.), 2001, Jul-13, Volume: 293, Issue:5528

    Topics: Adult; Amygdala; Analgesics, Opioid; Brain; Brain Mapping; Female; Fentanyl; Humans; Magnetic Resona

2001
A randomized controlled trial of fentanyl for abortion pain.
    American journal of obstetrics and gynecology, 2001, Volume: 185, Issue:1

    Topics: Abortion, Induced; Adult; Analgesics, Opioid; Anxiety; Depression; Female; Fentanyl; Humans; Pain; P

2001
Long-term safety of oral transmucosal fentanyl citrate for breakthrough cancer pain.
    Journal of pain and symptom management, 2001, Volume: 22, Issue:1

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Ambulatory Care; Analgesics, Opioid; Female; F

2001
Transdermal fentanyl therapy for pains in children with infantile neuronal ceroid lipofuscinosis.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2001, Volume: 5 Suppl A

    Topics: Administration, Cutaneous; Analgesics, Opioid; Child; Fentanyl; Humans; Neuronal Ceroid-Lipofuscinos

2001
A safe and effective method for converting cancer patients from intravenous to transdermal fentanyl.
    Cancer, 2001, Dec-15, Volume: 92, Issue:12

    Topics: Administration, Cutaneous; Adult; Aged; Analgesics, Opioid; Female; Fentanyl; Humans; Infusions, Int

2001
Use of TTS fentanyl as a single opioid for cancer pain relief: a safety and efficacy clinical trial in patients naive to mild or strong opioids.
    Oncology, 2002, Volume: 62, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Dose-Response Relationship, Drug; Female; Fentan

2002
Comparative study of etofenamate and fentanyl for outpatient extracorporeal shockwave lithotripsy.
    Scandinavian journal of urology and nephrology, 2001, Volume: 35, Issue:6

    Topics: Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Female; Fentanyl; Flufenam

2001
Reduction of pain on injection of propofol: a comparison of fentanyl with remifentanil.
    Anesthesia and analgesia, 2002, Volume: 94, Issue:4

    Topics: Analgesics, Opioid; Anesthetics, Intravenous; Fentanyl; Humans; Infusions, Intravenous; Pain; Pain M

2002
Pitfalls of opioid rotation: substituting another opioid for methadone in patients with cancer pain.
    Pain, 2002, Volume: 96, Issue:3

    Topics: Adult; Aged; Analgesics, Opioid; Female; Fentanyl; Humans; Hydromorphone; Levorphanol; Male; Methado

2002
Preoperative administration of controlled-release oxycodone for the management of pain after ambulatory laparoscopic tubal ligation surgery.
    Journal of clinical anesthesia, 2002, Volume: 14, Issue:3

    Topics: Adult; Ambulatory Surgical Procedures; Analgesics, Opioid; Delayed-Action Preparations; Double-Blind

2002
The prevention of pain from injection of rocuronium by ondansetron, lidocaine, tramadol, and fentanyl.
    Anesthesia and analgesia, 2002, Volume: 94, Issue:6

    Topics: Adult; Analgesics, Opioid; Androstanols; Anesthetics, Local; Double-Blind Method; Female; Fentanyl;

2002
Sublingual fentanyl citrate for cancer-related breakthrough pain: a pilot study.
    Palliative medicine, 2001, Volume: 15, Issue:4

    Topics: Administration, Sublingual; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Female; Fentanyl; Hu

2001
Paracervical block and elective abortion: the effect on pain of waiting between injection and procedure.
    American journal of obstetrics and gynecology, 2002, Volume: 186, Issue:6

    Topics: Abortion, Induced; Analgesics, Opioid; Cervix Uteri; Female; Fentanyl; Humans; Injections; Labor Sta

2002
Paracervical block and elective abortion: the effect on pain of waiting between injection and procedure.
    American journal of obstetrics and gynecology, 2002, Volume: 186, Issue:6

    Topics: Abortion, Induced; Analgesics, Opioid; Cervix Uteri; Female; Fentanyl; Humans; Injections; Labor Sta

2002
Paracervical block and elective abortion: the effect on pain of waiting between injection and procedure.
    American journal of obstetrics and gynecology, 2002, Volume: 186, Issue:6

    Topics: Abortion, Induced; Analgesics, Opioid; Cervix Uteri; Female; Fentanyl; Humans; Injections; Labor Sta

2002
Paracervical block and elective abortion: the effect on pain of waiting between injection and procedure.
    American journal of obstetrics and gynecology, 2002, Volume: 186, Issue:6

    Topics: Abortion, Induced; Analgesics, Opioid; Cervix Uteri; Female; Fentanyl; Humans; Injections; Labor Sta

2002
Narcotic analgesia: fentanyl reduces the intensity but not the unpleasantness of painful tooth pulp sensations.
    Science (New York, N.Y.), 1979, Mar-23, Volume: 203, Issue:4386

    Topics: Dental Pulp; Double-Blind Method; Electric Stimulation; Fentanyl; Humans; Injections, Intravenous; N

1979
Comparison of etomidate in combination with fentanyl or diazepam, with thiopentone as an induction agent for general anaesthesia.
    British journal of anaesthesia, 1979, Volume: 51, Issue:12

    Topics: Adult; Anesthesia, General; Diazepam; Etomidate; Fentanyl; Humans; Imidazoles; Middle Aged; Movement

1979
Effect of premedication on etomidate anaesthesia.
    British journal of anaesthesia, 1979, Volume: 51, Issue:12

    Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Atropine; Diazepam; Etomidate; Fentanyl; Humans; I

1979
[Fentanyl prevents the pain at the site of propofol injection].
    Minerva anestesiologica, 1992, Volume: 58, Issue:12

    Topics: Child; Child, Preschool; Fentanyl; Humans; Injections, Intravenous; Pain; Propofol

1992
[Pain control during the expulsion period in labor using bupivacaine and fentanyl].
    Minerva ginecologica, 1992, Volume: 44, Issue:10

    Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Bupivacaine; Drug Evaluation; Drug Therapy, Combinati

1992
Transdermal fentanyl: clinical trial at the University of Colorado Health Sciences Center.
    Journal of pain and symptom management, 1992, Volume: 7, Issue:3 Suppl

    Topics: Administration, Cutaneous; Adult; Female; Fentanyl; Humans; Male; Middle Aged; Neoplasms; Pain

1992
Transdermal fentanyl: seeding trial in patients with chronic cancer pain.
    Journal of pain and symptom management, 1992, Volume: 7, Issue:3 Suppl

    Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Female; Fentanyl; Humans; Male; Middle Aged; Neo

1992
Transdermal fentanyl for chronic cancer pain: detailed case reports and the influence of confounding factors.
    Journal of pain and symptom management, 1992, Volume: 7, Issue:3 Suppl

    Topics: Administration, Cutaneous; Aged; Chronic Disease; Confounding Factors, Epidemiologic; Female; Fentan

1992
Transdermal fentanyl use in hospice home-care patients with chronic cancer pain.
    Journal of pain and symptom management, 1992, Volume: 7, Issue:3 Suppl

    Topics: Administration, Cutaneous; Aged; Chronic Disease; Female; Fentanyl; Home Care Services; Hospices; Hu

1992
Management of cancer pain with transdermal fentanyl: phase IV trial, University of Iowa.
    Journal of pain and symptom management, 1992, Volume: 7, Issue:3 Suppl

    Topics: Administration, Cutaneous; Aged; Female; Fentanyl; Humans; Male; Middle Aged; Neoplasms; Pain

1992
[Analgesic effect of transcutaneous cranial electrostimulation in patients treated by Nd:YAG laser for cancer of the rectum. A double-blind randomized trial].
    Gastroenterologie clinique et biologique, 1992, Volume: 16, Issue:1

    Topics: Aged; Aged, 80 and over; Double-Blind Method; Electronarcosis; Female; Fentanyl; Humans; Intraoperat

1992
Midazolam versus fentanyl as premedication for painful procedures in children with cancer.
    Pediatrics, 1992, Volume: 89, Issue:4 Pt 1

    Topics: Adolescent; Anxiety; Bone Marrow Examination; Child; Child, Preschool; Conscious Sedation; Double-Bl

1992
Epidural fentanyl and caesarean section: when should fentanyl be given?
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1992, Volume: 39, Issue:4

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Apgar Score; Cesarean Section; Double-Blind Me

1992
Segmental analgesic effect and reduction of halothane MAC from epidural fentanyl in humans.
    Anesthesia and analgesia, 1992, Volume: 74, Issue:6

    Topics: Adult; Aged; Analgesia; Anesthesia, Epidural; Drug Interactions; Female; Fentanyl; Halothane; Humans

1992
Intravenous midazolam versus fentanyl as premedication for painful procedures in pediatric oncology patients.
    Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses, 1991, Volume: 8, Issue:2

    Topics: Adolescent; Adult; Child; Child, Preschool; Double-Blind Method; Fentanyl; Humans; Midazolam; Neopla

1991
Does combined epidural lignocaine and fentanyl provide better anaesthesia for ESWL than lignocaine alone?
    Anaesthesia and intensive care, 1991, Volume: 19, Issue:3

    Topics: Anesthesia, Epidural; Double-Blind Method; Drug Combinations; Female; Fentanyl; Humans; Kidney Calcu

1991
Prospective evaluation of epidural and intravenous administration of fentanyl for pain control and restoration of ventilatory function following multiple rib fractures.
    The Journal of trauma, 1991, Volume: 31, Issue:4

    Topics: Adult; Carbon Dioxide; Fentanyl; Humans; Infusions, Intravenous; Injections, Epidural; Multiple Trau

1991
Prospective evaluation of epidural and intravenous administration of fentanyl for pain control and restoration of ventilatory function following multiple rib fractures.
    The Journal of trauma, 1991, Volume: 31, Issue:4

    Topics: Adult; Carbon Dioxide; Fentanyl; Humans; Infusions, Intravenous; Injections, Epidural; Multiple Trau

1991
Prospective evaluation of epidural and intravenous administration of fentanyl for pain control and restoration of ventilatory function following multiple rib fractures.
    The Journal of trauma, 1991, Volume: 31, Issue:4

    Topics: Adult; Carbon Dioxide; Fentanyl; Humans; Infusions, Intravenous; Injections, Epidural; Multiple Trau

1991
Prospective evaluation of epidural and intravenous administration of fentanyl for pain control and restoration of ventilatory function following multiple rib fractures.
    The Journal of trauma, 1991, Volume: 31, Issue:4

    Topics: Adult; Carbon Dioxide; Fentanyl; Humans; Infusions, Intravenous; Injections, Epidural; Multiple Trau

1991
Differences in magnitude and duration of opioid-induced respiratory depression and analgesia with fentanyl and sufentanil.
    Anesthesia and analgesia, 1990, Volume: 70, Issue:1

    Topics: Adolescent; Adult; Analgesics; Carbon Dioxide; Fentanyl; Humans; Pain; Respiration; Sensory Threshol

1990
Continuous epidural infusion of 0.0625% bupivacaine-0.0002% fentanyl during the second stage of labor.
    Anesthesiology, 1990, Volume: 72, Issue:4

    Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Bupivacaine; Cesarean Section; Delivery, Obstetric; F

1990
Pain relief for outpatient colonoscopy: a comparison of alfentanil with fentanyl.
    Anaesthesia and intensive care, 1990, Volume: 18, Issue:2

    Topics: Adult; Aged; Alfentanil; Colonoscopy; Female; Fentanyl; Follow-Up Studies; Humans; Injections, Intra

1990
Relaxation response in femoral angiography.
    Radiology, 1990, Volume: 174, Issue:3 Pt 1

    Topics: Angiography; Anxiety; Diazepam; Femoral Artery; Fentanyl; Humans; Music; Pain; Random Allocation; Re

1990
Relationship between the pharmacokinetics and the analgesic and respiratory pharmacodynamics of epidural sufentanil.
    Clinical pharmacology and therapeutics, 1989, Volume: 46, Issue:4

    Topics: Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fentanyl; Humans; Injecti

1989
Measurement of post-operative pain and narcotic administration in infants using a new clinical scoring system.
    Intensive care medicine, 1989, Volume: 15 Suppl 1

    Topics: Fentanyl; Humans; Infant; Infant, Newborn; Pain; Pain Measurement; Postoperative Complications

1989
[Significance of endocrine parameters of stress].
    Der Anaesthesist, 1985, Volume: 34, Issue:6

    Topics: Adrenocorticotropic Hormone; Adult; Anesthesia, General; Clinical Trials as Topic; Coronary Artery B

1985
Fentanyl and bupivacaine mixture for extradural blockade in orthopaedic surgery: effects on haemodynamic responses and pain related to the use of thigh tourniquet.
    European journal of anaesthesiology, 1987, Volume: 4, Issue:3

    Topics: Adult; Anesthesia, Epidural; Blood Pressure; Bupivacaine; Clinical Trials as Topic; Double-Blind Met

1987
[Comparative clinical studies of the hemodynamic parameters by anesthesia combination with Nalbuphin (Nubain) and Fentanyl].
    Der Anaesthesist, 1987, Volume: 36, Issue:5

    Topics: Adolescent; Adult; Anesthesia, Endotracheal; Blood Pressure; Clinical Trials as Topic; Cognition; Do

1987
A multiple random staircase method of psychophysical pain assessment.
    Pain, 1988, Volume: 32, Issue:1

    Topics: Double-Blind Method; Fentanyl; Hot Temperature; Humans; Pain; Pain Measurement; Random Allocation; S

1988
Simple devices in differentiating the effects of buprenorphine and fentanyl in healthy volunteers.
    European journal of clinical pharmacology, 1987, Volume: 31, Issue:6

    Topics: Adult; Blood Pressure; Buprenorphine; Female; Fentanyl; Flicker Fusion; Heart Rate; Humans; Hypnotic

1987
Reliability and validity of verbal descriptor scales of painfulness.
    Pain, 1987, Volume: 29, Issue:2

    Topics: Adolescent; Adult; Diazepam; Electric Stimulation; Female; Fentanyl; Humans; Male; Pain; Pain Measur

1987
Naloxone, fentanyl, and diazepam modify plasma beta-endorphin levels during surgery.
    Clinical pharmacology and therapeutics, 1986, Volume: 40, Issue:2

    Topics: Diazepam; Double-Blind Method; Drug Evaluation; Endorphins; Fentanyl; Humans; Intraoperative Period;

1986
Prolonged antagonism of opioid action with intravenous nalmefene in man.
    Anesthesiology, 1986, Volume: 64, Issue:2

    Topics: Adult; Drug Interactions; Fentanyl; Humans; Male; Muscle Rigidity; Naltrexone; Pain; Respiration; Ti

1986
Effects of three anaesthesia methods on haemodynamic responses connected with the use of thigh tourniquet in orthopaedic patients.
    Acta anaesthesiologica Scandinavica, 1985, Volume: 29, Issue:1

    Topics: Adult; Anesthesia, Epidural; Anesthesia, General; Anesthesia, Spinal; Blood Pressure; Bupivacaine; C

1985
Etomidate versus thiopental for induction of anesthesia.
    Anesthesia and analgesia, 1985, Volume: 64, Issue:9

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Anesthesia, General; Anesthesia, Inhalation; Anesthes

1985
Alterations in response to somatic pain associated with anaesthesia. XIX: Studies with the drugs used in neuroleptanaesthesia.
    British journal of anaesthesia, 1970, Volume: 42, Issue:10

    Topics: Affect; Benperidol; Clinical Trials as Topic; Diazepam; Drug Synergism; Female; Fentanyl; Heroin; Hu

1970

Other Studies

690 other studies available for fentanyl and Pain

ArticleYear
Development of a bioavailable μ opioid receptor (MOPr) agonist, δ opioid receptor (DOPr) antagonist peptide that evokes antinociception without development of acute tolerance.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Analgesics; Animals; Biological Availability; Drug Tolerance; Female; Glioma; Male; Mice; Mice, Inbr

2014
Opioid-induced adrenal insufficiency in transdermal fentanyl treatment: a revisited diagnosis in clinical setting.
    Endocrine journal, 2022, Feb-28, Volume: 69, Issue:2

    Topics: Adrenal Insufficiency; Analgesics, Opioid; Constipation; Female; Fentanyl; Humans; Middle Aged; Neop

2022
Fentanyl analgesia in asphyxiated newborns treated with therapeutic hypothermia.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2022, Volume: 35, Issue:25

    Topics: Analgesia; Asphyxia Neonatorum; Fentanyl; Humans; Hypothermia; Hypothermia, Induced; Hypoxia-Ischemi

2022
Subanalgesic morphine doses augment fentanyl analgesia by interacting with delta opioid receptors in male rats.
    Journal of neuroscience research, 2022, Volume: 100, Issue:1

    Topics: Analgesia; Analgesics, Opioid; Animals; Fentanyl; Male; Morphine; Pain; Rats; Receptors, Opioid, del

2022
Pre-hospital oral transmucosal fentanyl citrate for trauma analgesia: preliminary experience and implications for civilian mass casualty response.
    British journal of anaesthesia, 2022, Volume: 128, Issue:2

    Topics: Administration, Oral; Adult; Analgesia; Analgesics, Opioid; Emergency Medical Services; Female; Fent

2022
Transdermal Fentanyl Usage in Working-age Patients Undergoing Cancer Treatment: Prescription Pattern Analysis Using Large Claims Data in Japan.
    Journal of pain & palliative care pharmacotherapy, 2021, Volume: 35, Issue:4

    Topics: Administration, Cutaneous; Adult; Analgesics, Opioid; Fentanyl; Humans; Japan; Male; Middle Aged; Ne

2021
Inhibition of Oligodendrocyte Apoptosis in the Prelimbic Medial Prefrontal Cortex Prevents Fentanyl-induced Hyperalgesia in Rats.
    The journal of pain, 2022, Volume: 23, Issue:6

    Topics: Analgesics, Opioid; Animals; Apoptosis; Fentanyl; Hyperalgesia; Oligodendroglia; Pain; Prefrontal Co

2022
Study on the Mechanism of Fentanyl in Pain Treatment Based on Network Pharmacology.
    Journal of healthcare engineering, 2022, Volume: 2022

    Topics: Fentanyl; Humans; Network Pharmacology; Pain; Signal Transduction

2022
In vitro and in vivo pharmaco-dynamic study of the novel fentanyl derivatives: Acrylfentanyl, Ocfentanyl and Furanylfentanyl.
    Neuropharmacology, 2022, 05-15, Volume: 209

    Topics: Analgesics, Opioid; Animals; beta-Arrestin 2; Fentanyl; Furans; Male; Mice; Pain; Receptors, Opioid;

2022
Ketamine vs fentanyl for ED treatment of pain.
    The American journal of emergency medicine, 2022, Volume: 58

    Topics: Analgesics; Analgesics, Opioid; Double-Blind Method; Fentanyl; Humans; Ketamine; Pain

2022
Predicting transdermal fentanyl delivery using physics-based simulations for tailored therapy based on the age.
    Drug delivery, 2022, Volume: 29, Issue:1

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Fentanyl; Humans; Mid

2022
Tracheostomy decreases continuous analgesia and sedation requirements.
    The journal of trauma and acute care surgery, 2022, 10-01, Volume: 93, Issue:4

    Topics: Adult; Aged; Analgesia; Analgesics; Anti-Anxiety Agents; Endrin; Female; Fentanyl; Humans; Hypnotics

2022
Safety and Efficacy of Sufentanil and Fentanyl Analgesia in Patients with Traumatic Brain Injury: A Retrospective Study.
    Medical science monitor : international medical journal of experimental and clinical research, 2022, May-13, Volume: 28

    Topics: Analgesia; Brain Injuries, Traumatic; Fentanyl; Humans; Pain; Retrospective Studies; Sufentanil

2022
Acceptability of a Fentanyl Vaccine to Prevent Opioid Overdose and Need for Personalized Decision-Making.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2022, 08-15, Volume: 75, Issue:Suppl 1

    Topics: Adult; Analgesics, Opioid; COVID-19; Drug Overdose; Female; Fentanyl; Humans; Male; Opiate Overdose;

2022
Evaluation of opioid consumption trends for pain in Taiwan and comparison with neighboring Asian countries.
    Journal of food and drug analysis, 2022, 03-15, Volume: 30, Issue:1

    Topics: Analgesics, Opioid; Codeine; Fentanyl; Humans; Meperidine; Morphine; Pain; Taiwan

2022
L-NAC reverses of the adverse effects of fentanyl infusion on ventilation and blood-gas chemistry.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 153

    Topics: Acetylcysteine; Analgesics, Opioid; Animals; Fentanyl; Humans; Lysine; Male; Pain; Rats; Rats, Sprag

2022
Atypical dermatologic manifestations in complex regional pain syndrome: a case report.
    Journal of medical case reports, 2022, Jun-27, Volume: 16, Issue:1

    Topics: Adult; Complex Regional Pain Syndromes; Extremities; Fentanyl; Humans; Male; Pain; Pain Measurement

2022
Intranasal Fentanyl for On-the-Hill Analgesia by Ski Patrol.
    Wilderness & environmental medicine, 2022, Volume: 33, Issue:3

    Topics: Administration, Intranasal; Analgesia; Analgesics; Analgesics, Opioid; Fentanyl; Humans; Naloxone; P

2022
Prevalence and Perinatal Outcomes Following In Utero Exposure to Prehospital Emergency Methoxyflurane: A 17-Year Retrospective Cohort Study.
    Paediatric drugs, 2022, Volume: 24, Issue:5

    Topics: Emergency Medical Services; Female; Fentanyl; Humans; Infant, Newborn; Methoxyflurane; Pain; Pregnan

2022
Effect of Transdermal Fentanyl Patch Combined with Enhanced Recovery after Surgery on the Curative Effect and Analgesic Effect of Liver Cancer.
    BioMed research international, 2022, Volume: 2022

    Topics: Administration, Cutaneous; Analgesics, Opioid; Cancer Pain; Enhanced Recovery After Surgery; Fentany

2022
Suspected opioid-induced hyperalgesia in an infant following surgery: A case report.
    Journal of clinical pharmacy and therapeutics, 2022, Volume: 47, Issue:9

    Topics: Adult; Analgesics, Opioid; Fentanyl; Humans; Hyperalgesia; Infant; Ketamine; Male; Pain

2022
Sex-specific role of the circadian transcription factor NPAS2 in opioid tolerance, withdrawal and analgesia.
    Genes, brain, and behavior, 2022, Volume: 21, Issue:7

    Topics: Analgesia; Analgesics; Analgesics, Opioid; Animals; Basic Helix-Loop-Helix Transcription Factors; Dr

2022
Trends in prehospital pain management: two decades of point-of-injury care.
    The Israel Medical Association journal : IMAJ, 2022, Volume: 24, Issue:9

    Topics: Adult; Analgesics; Emergency Medical Services; Female; Fentanyl; Humans; Male; Military Personnel; M

2022
Update: Correlation of Fentanyl Positive Drug Screens with other Medications in Patients from Pain, Rehabilitation and Behavioral Programs.
    Annals of clinical and laboratory science, 2022, Volume: 52, Issue:5

    Topics: Analgesics, Opioid; Fentanyl; Humans; Illicit Drugs; Methamphetamine; Pain; Substance-Related Disord

2022
Aloe Vera-Containing Matrix in Transdermal Fentanyl Therapy Improves Adhesion, Skin Tolerance and Quality of Life: Results of a German Multicenter Study with a New Fentanyl Patch.
    Drug research, 2023, Volume: 73, Issue:2

    Topics: Administration, Cutaneous; Aloe; Analgesics, Opioid; Fentanyl; Humans; Pain; Quality of Life; Transd

2023
Case Reports of Transdermal Fentanyl Patch Administration Difficulties in Cancer Patients with Excess Sweating.
    Journal of pain & palliative care pharmacotherapy, 2023, Volume: 37, Issue:1

    Topics: Administration, Cutaneous; Adult; Analgesics, Opioid; Fentanyl; Humans; Male; Middle Aged; Neoplasms

2023
Case Reports of Transdermal Fentanyl Patch Administration Difficulties in Cancer Patients with Excess Sweating.
    Journal of pain & palliative care pharmacotherapy, 2023, Volume: 37, Issue:1

    Topics: Administration, Cutaneous; Adult; Analgesics, Opioid; Fentanyl; Humans; Male; Middle Aged; Neoplasms

2023
Case Reports of Transdermal Fentanyl Patch Administration Difficulties in Cancer Patients with Excess Sweating.
    Journal of pain & palliative care pharmacotherapy, 2023, Volume: 37, Issue:1

    Topics: Administration, Cutaneous; Adult; Analgesics, Opioid; Fentanyl; Humans; Male; Middle Aged; Neoplasms

2023
Case Reports of Transdermal Fentanyl Patch Administration Difficulties in Cancer Patients with Excess Sweating.
    Journal of pain & palliative care pharmacotherapy, 2023, Volume: 37, Issue:1

    Topics: Administration, Cutaneous; Adult; Analgesics, Opioid; Fentanyl; Humans; Male; Middle Aged; Neoplasms

2023
Case Reports of Transdermal Fentanyl Patch Administration Difficulties in Cancer Patients with Excess Sweating.
    Journal of pain & palliative care pharmacotherapy, 2023, Volume: 37, Issue:1

    Topics: Administration, Cutaneous; Adult; Analgesics, Opioid; Fentanyl; Humans; Male; Middle Aged; Neoplasms

2023
Case Reports of Transdermal Fentanyl Patch Administration Difficulties in Cancer Patients with Excess Sweating.
    Journal of pain & palliative care pharmacotherapy, 2023, Volume: 37, Issue:1

    Topics: Administration, Cutaneous; Adult; Analgesics, Opioid; Fentanyl; Humans; Male; Middle Aged; Neoplasms

2023
Case Reports of Transdermal Fentanyl Patch Administration Difficulties in Cancer Patients with Excess Sweating.
    Journal of pain & palliative care pharmacotherapy, 2023, Volume: 37, Issue:1

    Topics: Administration, Cutaneous; Adult; Analgesics, Opioid; Fentanyl; Humans; Male; Middle Aged; Neoplasms

2023
Case Reports of Transdermal Fentanyl Patch Administration Difficulties in Cancer Patients with Excess Sweating.
    Journal of pain & palliative care pharmacotherapy, 2023, Volume: 37, Issue:1

    Topics: Administration, Cutaneous; Adult; Analgesics, Opioid; Fentanyl; Humans; Male; Middle Aged; Neoplasms

2023
Case Reports of Transdermal Fentanyl Patch Administration Difficulties in Cancer Patients with Excess Sweating.
    Journal of pain & palliative care pharmacotherapy, 2023, Volume: 37, Issue:1

    Topics: Administration, Cutaneous; Adult; Analgesics, Opioid; Fentanyl; Humans; Male; Middle Aged; Neoplasms

2023
Hepatic Hilar Nerve Block for Adjunctive Analgesia during Percutaneous Thermal Ablation of Hepatic Tumors: A Retrospective Analysis.
    Journal of vascular and interventional radiology : JVIR, 2023, Volume: 34, Issue:3

    Topics: Aged; Analgesia; Fentanyl; Humans; Liver Neoplasms; Midazolam; Nerve Block; Pain; Retrospective Stud

2023
Hepatic Hilar Nerve Block for Adjunctive Analgesia during Percutaneous Thermal Ablation of Hepatic Tumors: A Retrospective Analysis.
    Journal of vascular and interventional radiology : JVIR, 2023, Volume: 34, Issue:3

    Topics: Aged; Analgesia; Fentanyl; Humans; Liver Neoplasms; Midazolam; Nerve Block; Pain; Retrospective Stud

2023
Hepatic Hilar Nerve Block for Adjunctive Analgesia during Percutaneous Thermal Ablation of Hepatic Tumors: A Retrospective Analysis.
    Journal of vascular and interventional radiology : JVIR, 2023, Volume: 34, Issue:3

    Topics: Aged; Analgesia; Fentanyl; Humans; Liver Neoplasms; Midazolam; Nerve Block; Pain; Retrospective Stud

2023
Hepatic Hilar Nerve Block for Adjunctive Analgesia during Percutaneous Thermal Ablation of Hepatic Tumors: A Retrospective Analysis.
    Journal of vascular and interventional radiology : JVIR, 2023, Volume: 34, Issue:3

    Topics: Aged; Analgesia; Fentanyl; Humans; Liver Neoplasms; Midazolam; Nerve Block; Pain; Retrospective Stud

2023
IF IM in a crisis: Intranasal fentanyl versus intravenous morphine in adult vaso-occlusive crisis.
    The American journal of emergency medicine, 2023, Volume: 64

    Topics: Administration, Intranasal; Adolescent; Adult; Analgesics, Opioid; Anemia, Sickle Cell; Bradycardia;

2023
IF IM in a crisis: Intranasal fentanyl versus intravenous morphine in adult vaso-occlusive crisis.
    The American journal of emergency medicine, 2023, Volume: 64

    Topics: Administration, Intranasal; Adolescent; Adult; Analgesics, Opioid; Anemia, Sickle Cell; Bradycardia;

2023
IF IM in a crisis: Intranasal fentanyl versus intravenous morphine in adult vaso-occlusive crisis.
    The American journal of emergency medicine, 2023, Volume: 64

    Topics: Administration, Intranasal; Adolescent; Adult; Analgesics, Opioid; Anemia, Sickle Cell; Bradycardia;

2023
IF IM in a crisis: Intranasal fentanyl versus intravenous morphine in adult vaso-occlusive crisis.
    The American journal of emergency medicine, 2023, Volume: 64

    Topics: Administration, Intranasal; Adolescent; Adult; Analgesics, Opioid; Anemia, Sickle Cell; Bradycardia;

2023
Pain, Nausea, and Hospital Admission after Uterine Fibroid Embolization: A Comparison of 2 Protocols.
    Journal of vascular and interventional radiology : JVIR, 2023, Volume: 34, Issue:4

    Topics: Embolization, Therapeutic; Female; Fentanyl; Hospitalization; Hospitals; Humans; Leiomyoma; Nausea;

2023
Pain, Nausea, and Hospital Admission after Uterine Fibroid Embolization: A Comparison of 2 Protocols.
    Journal of vascular and interventional radiology : JVIR, 2023, Volume: 34, Issue:4

    Topics: Embolization, Therapeutic; Female; Fentanyl; Hospitalization; Hospitals; Humans; Leiomyoma; Nausea;

2023
Pain, Nausea, and Hospital Admission after Uterine Fibroid Embolization: A Comparison of 2 Protocols.
    Journal of vascular and interventional radiology : JVIR, 2023, Volume: 34, Issue:4

    Topics: Embolization, Therapeutic; Female; Fentanyl; Hospitalization; Hospitals; Humans; Leiomyoma; Nausea;

2023
Pain, Nausea, and Hospital Admission after Uterine Fibroid Embolization: A Comparison of 2 Protocols.
    Journal of vascular and interventional radiology : JVIR, 2023, Volume: 34, Issue:4

    Topics: Embolization, Therapeutic; Female; Fentanyl; Hospitalization; Hospitals; Humans; Leiomyoma; Nausea;

2023
Abuse, dependence and withdrawal associated with fentanyl and the role of its (designated) route of administration: an analysis of spontaneous reports from Europe.
    European journal of clinical pharmacology, 2023, Volume: 79, Issue:2

    Topics: Administration, Cutaneous; Analgesics, Opioid; Europe; Female; Fentanyl; Humans; Male; Middle Aged;

2023
Abuse, dependence and withdrawal associated with fentanyl and the role of its (designated) route of administration: an analysis of spontaneous reports from Europe.
    European journal of clinical pharmacology, 2023, Volume: 79, Issue:2

    Topics: Administration, Cutaneous; Analgesics, Opioid; Europe; Female; Fentanyl; Humans; Male; Middle Aged;

2023
Abuse, dependence and withdrawal associated with fentanyl and the role of its (designated) route of administration: an analysis of spontaneous reports from Europe.
    European journal of clinical pharmacology, 2023, Volume: 79, Issue:2

    Topics: Administration, Cutaneous; Analgesics, Opioid; Europe; Female; Fentanyl; Humans; Male; Middle Aged;

2023
Abuse, dependence and withdrawal associated with fentanyl and the role of its (designated) route of administration: an analysis of spontaneous reports from Europe.
    European journal of clinical pharmacology, 2023, Volume: 79, Issue:2

    Topics: Administration, Cutaneous; Analgesics, Opioid; Europe; Female; Fentanyl; Humans; Male; Middle Aged;

2023
Analgesic effect of epidural anesthesia via the intervertebral foramen approach in percutaneous transforaminal endoscopic discectomy: a retrospective study.
    BMC anesthesiology, 2022, 12-20, Volume: 22, Issue:1

    Topics: Anesthesia, Epidural; Diskectomy; Endoscopy; Fentanyl; Humans; Intervertebral Disc Displacement; Lum

2022
Intranasal fentanyl and discharge from the emergency department among children with sickle cell disease and vaso-occlusive pain: A multicenter pediatric emergency medicine perspective.
    American journal of hematology, 2023, Volume: 98, Issue:4

    Topics: Analgesics, Opioid; Anemia, Sickle Cell; Child; Cross-Sectional Studies; Emergency Service, Hospital

2023
Oral transmucosal fentanyl citrate analgesia in prehospital trauma care: an observational cohort study.
    Scandinavian journal of trauma, resuscitation and emergency medicine, 2023, Jan-07, Volume: 31, Issue:1

    Topics: Administration, Oral; Analgesia; Analgesics, Opioid; Cohort Studies; Emergency Medical Services; Fem

2023
Impact of fentanyl analgesia on the accuracy of HVPG measurements in patients with cirrhosis: a prospective, multicenter study.
    Hepatology communications, 2023, 01-01, Volume: 7, Issue:1

    Topics: Analgesia; Fentanyl; Humans; Liver Cirrhosis; Pain; Propofol; Prospective Studies

2023
HCN-Channel-Dependent Hyperexcitability of the Layer V Pyramidal Neurons in IL-mPFC Contributes to Fentanyl-Induced Hyperalgesia in Male Rats.
    Molecular neurobiology, 2023, Volume: 60, Issue:5

    Topics: Animals; Fentanyl; Hyperalgesia; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Male;

2023
Pre-hospital analgesia in pediatric trauma and critically ill patients: An analysis of a German air rescue service.
    Scandinavian journal of trauma, resuscitation and emergency medicine, 2023, Jan-28, Volume: 31, Issue:1

    Topics: Analgesia; Analgesics; Analgesics, Opioid; Child; Critical Illness; Emergency Medical Services; Fent

2023
Histamine H1 receptor antagonist attenuates catecholamine surge and organ injury after severe burns.
    Frontiers in endocrinology, 2023, Volume: 14

    Topics: Animals; Cetirizine; Fentanyl; Histamine; Histamine H1 Antagonists; Midazolam; Pain; Promethazine; R

2023
An individualized digital twin of a patient for transdermal fentanyl therapy for chronic pain management.
    Drug delivery and translational research, 2023, Volume: 13, Issue:9

    Topics: Administration, Cutaneous; Analgesics, Opioid; Fentanyl; Humans; Neoplasms; Pain; Pain Management

2023
The association of patient age, race, and demographic features on reported pain and sedation dosing during procedural abortion: A retrospective cohort study.
    Contraception, 2023, Volume: 123

    Topics: Abortion, Induced; Ambulatory Care Facilities; Conscious Sedation; Demography; Female; Fentanyl; Hum

2023
Drug use patterns and factors related to the use and discontinuation of medications for opioid use disorder in the age of fentanyl: findings from a mixed-methods study of people who use drugs.
    Substance abuse treatment, prevention, and policy, 2023, 05-22, Volume: 18, Issue:1

    Topics: Analgesics, Opioid; Benzodiazepines; Buprenorphine; Crack Cocaine; Drug Overdose; Fentanyl; Heroin;

2023
Effect of nalbuphine plus ropivacaine on vaginal labor in epidural analgesia.
    BMC anesthesiology, 2023, 07-22, Volume: 23, Issue:1

    Topics: Analgesia, Epidural; Female; Fentanyl; Humans; Infant, Newborn; Nalbuphine; Pain; Pregnancy; Retrosp

2023
Fentanyl and the Fluorinated Fentanyl Derivative NFEPP Elicit Distinct Hydrogen-Bond Dynamics of the Opioid Receptor.
    Journal of chemical information and modeling, 2023, 08-14, Volume: 63, Issue:15

    Topics: Analgesics, Opioid; Fentanyl; Humans; Hydrogen; Pain; Receptors, Opioid; Receptors, Opioid, mu

2023
Continuous fentanyl administration and spontaneous withdrawal decreases home cage wheel running in rats with and without hindpaw inflammation.
    Physiology & behavior, 2023, Dec-01, Volume: 272

    Topics: Animals; Fentanyl; Freund's Adjuvant; Inflammation; Motor Activity; Pain; Rats

2023
Continuous visualization and validation of pain in critically ill patients using artificial intelligence: a retrospective observational study.
    Scientific reports, 2023, 10-14, Volume: 13, Issue:1

    Topics: Adult; Artificial Intelligence; Critical Care; Critical Illness; Fentanyl; Humans; Intensive Care Un

2023
Transdermal fentanyl to parenteral morphine route switch and drug rotation in refractory cancer cachexia.
    BMJ supportive & palliative care, 2022, Volume: 12, Issue:e2

    Topics: Administration, Cutaneous; Analgesics, Opioid; Cachexia; Female; Fentanyl; Humans; Morphine; Neoplas

2022
Characterizing Fentanyl Variability Using Population Pharmacokinetics in Pediatric Burn Patients.
    Journal of burn care & research : official publication of the American Burn Association, 2020, 01-30, Volume: 41, Issue:1

    Topics: Adolescent; Age Factors; Analgesics, Opioid; Body Size; Burns; Child; Child, Preschool; Female; Fent

2020
Ethnic disparities in pain processing among healthy adults: μ-opioid receptor binding potential as a putative mechanism.
    Pain, 2020, Volume: 161, Issue:4

    Topics: Adult; Brain; Ethnicity; Female; Fentanyl; Humans; Male; Pain; Pain Threshold; Positron-Emission Tom

2020
Nebulized Fentanyl for Dyspnea: A Retrospective Chart Review.
    Journal of pain & palliative care pharmacotherapy, 2020, Volume: 34, Issue:2

    Topics: Administration, Inhalation; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Dyspnea; Female; Fen

2020
[Analgesia for trauma patients in emergency medicine].
    Der Anaesthesist, 2020, Volume: 69, Issue:2

    Topics: Analgesia; Emergency Medical Services; Emergency Medicine; Fentanyl; Humans; Ketamine; Pain; Pain Ma

2020
Fentanyl impairs but ketamine preserves the microcirculatory response to hemorrhage.
    The journal of trauma and acute care surgery, 2020, Volume: 89, Issue:2S Suppl 2

    Topics: Administration, Topical; Analgesics; Analgesics, Opioid; Animals; Blood Pressure; Fentanyl; Heart Ra

2020
Correlation of Fentanyl Positive Drug Screens with Other Medications in Patients from Pain, Rehabilitation and Behavioral Programs.
    Annals of clinical and laboratory science, 2020, Volume: 50, Issue:2

    Topics: Behavior Control; Drug Overdose; Fentanyl; Humans; Pain; Pharmaceutical Preparations; Rehabilitation

2020
Influences of UGT2B7 rs7439366 and rs12233719 Polymorphisms on Fentanyl Sensitivity in Chinese Gynecologic Patients.
    Medical science monitor : international medical journal of experimental and clinical research, 2020, May-13, Volume: 26

    Topics: Adult; Alleles; Asian People; Biomarkers, Pharmacological; China; Female; Fentanyl; Gene Frequency;

2020
[Analysis of Symptoms Relieved in Addition to Pain after Administration of Oxycodone or Morphine to Patients with Advanced Cancer Living at Home].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2020, Volume: 47, Issue:5

    Topics: Administration, Cutaneous; Analgesics, Opioid; Cancer Pain; Fentanyl; Humans; Morphine; Neoplasms; O

2020
Potential Energy Function for Fentanyl-Based Opioid Pain Killers.
    Journal of chemical information and modeling, 2020, 07-27, Volume: 60, Issue:7

    Topics: Analgesics; Analgesics, Opioid; Fentanyl; Humans; Pain; Receptors, Opioid, mu

2020
Improvement of Pain Relief of Fentanyl Citrate Drug Encapsulated in Nanostructured Lipid Carrier: Drug Formulation, Parameter Optimization, in vitro and in vivo Studies.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: Animals; Capsules; Drug Carriers; Drug Compounding; Drug Liberation; Fentanyl; Lipids; Male; Nanostr

2020
Interaction of auditory and pain pathways: Effects of stimulus intensity, hearing loss and opioid signaling.
    Hearing research, 2020, Volume: 393

    Topics: Analgesics, Opioid; Animals; Auditory Threshold; Deafness; Fentanyl; Hearing Loss; Hearing Loss, Noi

2020
Synthesis and pharmacological evaluation of novel cis and trans 3-substituted anilidopiperidines.
    Pharmacological reports : PR, 2020, Volume: 72, Issue:4

    Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Fentanyl; Mice; Pain; Pain Measuremen

2020
Fentanyl patches: Use and Misuse.
    Acute medicine, 2020, Volume: 19, Issue:2

    Topics: Administration, Cutaneous; Analgesics, Opioid; Fentanyl; Humans; Pain

2020
Pain management in patients with chronic kidney disease and end-stage kidney disease.
    Current opinion in nephrology and hypertension, 2020, Volume: 29, Issue:6

    Topics: Analgesics, Opioid; Buprenorphine; Fentanyl; Humans; Hydromorphone; Kidney Failure, Chronic; Oxycodo

2020
Perioperative pain control and tympanostomy tube outcomes.
    International journal of pediatric otorhinolaryngology, 2020, Volume: 138

    Topics: Child, Preschool; Fentanyl; Humans; Infant; Ketorolac; Middle Ear Ventilation; Otitis Media with Eff

2020
Divergent profiles of fentanyl withdrawal and associated pain in mice and rats.
    Pharmacology, biochemistry, and behavior, 2021, Volume: 200

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Female; Fentanyl; Humans; Hyperalgesia; Locomotion; M

2021
Lack of effect of different pain-related manipulations on opioid self-administration, reinstatement of opioid seeking, and opioid choice in rats.
    Psychopharmacology, 2021, Volume: 238, Issue:7

    Topics: Analgesics, Opioid; Animals; Choice Behavior; Conditioning, Operant; Drug-Seeking Behavior; Extincti

2021
Glutathione ethyl ester reverses the deleterious effects of fentanyl on ventilation and arterial blood-gas chemistry while prolonging fentanyl-induced analgesia.
    Scientific reports, 2021, 03-26, Volume: 11, Issue:1

    Topics: Analgesia; Analgesics, Opioid; Animals; Blood Gas Analysis; Carbon Dioxide; Drug Discovery; Fentanyl

2021
Preventive Analgesia, Hemodynamic Stability, and Pain in Vitreoretinal Surgery.
    Medicina (Kaunas, Lithuania), 2021, Mar-12, Volume: 57, Issue:3

    Topics: Analgesia; Analgesics, Opioid; Fentanyl; Hemodynamics; Humans; Pain; Pain, Postoperative; Vitreoreti

2021
Pharmacological characterization of naloxegol: In vitro and in vivo studies.
    European journal of pharmacology, 2021, Jul-15, Volume: 903

    Topics: Administration, Oral; Analgesics, Opioid; Animals; Behavior, Animal; Calcium; CHO Cells; Constipatio

2021
Long-Term Analgesia following a Single Application of Fentanyl Transdermal Solution in Pigs.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 2021, Volume: 62, Issue:2

    Topics: Administration, Cutaneous; Analgesia; Analgesics, Opioid; Animals; Buprenorphine; Dogs; Fentanyl; Pa

2021
Pain medication requirements in patients with opioid use disorder at the time of surgical abortion: An exploratory study.
    Contraception, 2021, Volume: 104, Issue:4

    Topics: Conscious Sedation; Female; Fentanyl; Humans; Hypnotics and Sedatives; Midazolam; Opioid-Related Dis

2021
Patient satisfaction with procedural sedation in the emergency department.
    Emergency medicine Australasia : EMA, 2017, Volume: 29, Issue:3

    Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Conscious Sedation; Emergency Service, Hospital; Female

2017
ABCB1 genotype is associated with fentanyl requirements in critically ill children.
    Pediatric research, 2017, Volume: 82, Issue:1

    Topics: Alleles; Analgesics, Opioid; ATP Binding Cassette Transporter, Subfamily B; Child; Child, Preschool;

2017
A National Multicenter Survey on Management of Pain, Agitation, and Delirium in Intensive Care Units in China.
    Chinese medical journal, 2017, May-20, Volume: 130, Issue:10

    Topics: Delirium; Dexmedetomidine; Fentanyl; Haloperidol; Humans; Hypnotics and Sedatives; Intensive Care Un

2017
Comparison of Fentanyl Oral and Nasal Formulations #331.
    Journal of palliative medicine, 2017, Volume: 20, Issue:7

    Topics: Administration, Intranasal; Administration, Oral; Analgesics, Opioid; Fentanyl; Humans; Pain

2017
Pharmacokinetics of a Novel, Transdermal Fentanyl Solution in Rhesus Macaques (
    Journal of the American Association for Laboratory Animal Science : JAALAS, 2017, Jul-01, Volume: 56, Issue:4

    Topics: Administration, Cutaneous; Analgesics, Opioid; Animals; Cross-Over Studies; Female; Fentanyl; Half-L

2017
Variations in pediatric emergency medicine physician practices for intravenous fluid management in children with sickle cell disease and vaso-occlusive pain: A single institution experience.
    Pediatric blood & cancer, 2018, Volume: 65, Issue:1

    Topics: Administration, Intravenous; Adolescent; Adult; Analgesics, Opioid; Anemia, Sickle Cell; Child; Chil

2018
Between a rock and a hard place: Prescription opioid restrictions in the time of fentanyl and other street drug adulterants.
    Canadian journal of public health = Revue canadienne de sante publique, 2017, Sep-14, Volume: 108, Issue:3

    Topics: Analgesics, Opioid; Canada; Drug Contamination; Fentanyl; Harm Reduction; Health Policy; Humans; Ill

2017
Intranasal Fentanyl and Quality of Pediatric Acute Care.
    The Journal of emergency medicine, 2017, Volume: 53, Issue:5

    Topics: Administration, Intranasal; Administration, Intravenous; Adolescent; Analgesics, Opioid; Child; Chil

2017
A case-history illustrates importance of knowledge of drug-interactions when pain-patients are prescribed non-pain drugs for co-morbidities.
    Scandinavian journal of pain, 2017, Volume: 17

    Topics: Aged; Comorbidity; Diclofenac; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; F

2017
Nitrous Oxide 70% for Procedural Analgosedation in a Pediatric Emergency Department-With or Without Intranasal Fentanyl?
    Pediatric emergency care, 2019, Volume: 35, Issue:11

    Topics: Administration, Intranasal; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Drug Therapy, Combi

2019
Intranasal fentanyl improves time to analgesic delivery in sickle cell pain crises.
    The American journal of emergency medicine, 2018, Volume: 36, Issue:7

    Topics: Administration, Intranasal; Adolescent; Analgesics, Opioid; Anemia, Sickle Cell; Female; Fentanyl; H

2018
Intranasal fentanyl for acute severe pain episodes control in a dog.
    Veterinary anaesthesia and analgesia, 2017, Volume: 44, Issue:6

    Topics: Administration, Intranasal; Analgesics, Opioid; Animals; Dog Diseases; Dogs; Female; Fentanyl; Pain

2017
Difficulties in Pain Management Using Oxycodone and Fentanyl in Enzalutamide-Treated Patients With Advanced Prostate Cancer.
    Journal of pain and symptom management, 2018, Volume: 55, Issue:4

    Topics: Aged; Analgesics, Opioid; Antineoplastic Agents; Benzamides; Bone Neoplasms; Drug Interactions; Fent

2018
Pain Relief: Is this patient in pain or seeking a fentanyl fix.
    JEMS : a journal of emergency medical services, 2016, Volume: 41, Issue:11

    Topics: Analgesics, Opioid; Emergency Medical Services; Fentanyl; Humans; Pain; Pain Management; Pain Measur

2016
Effects of the Introduction of Intranasal Fentanyl on Reduction of Pain Severity Score in Children: An Interrupted Time-Series Analysis.
    Pediatric emergency care, 2019, Volume: 35, Issue:11

    Topics: Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Child, Preschool; Emergency Medic

2019
Pediatric emergency department triage-based pain guideline utilizing intranasal fentanyl: Effect of implementation.
    The American journal of emergency medicine, 2018, Volume: 36, Issue:9

    Topics: Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Child, Preschool; Female; Fentany

2018
Fentanyl lozenge story part 2: from military procurement to package.
    Journal of the Royal Army Medical Corps, 2018, Volume: 164, Issue:6

    Topics: Administration, Buccal; Analgesics, Opioid; Drug Administration Schedule; Drug Packaging; Fentanyl;

2018
Opioid analgesia on the battlefield: a retrospective review of data from Operation HERRICK.
    Journal of the Royal Army Medical Corps, 2018, Volume: 164, Issue:5

    Topics: Adolescent; Adult; Afghan Campaign 2001-; Afghanistan; Analgesics, Opioid; Child; Child, Preschool;

2018
Doctor shopping of opioid analgesics relative to benzodiazepines: A pharmacoepidemiological study among 11.7 million inhabitants in the French countries.
    Drug and alcohol dependence, 2018, 06-01, Volume: 187

    Topics: Adult; Analgesics, Opioid; Benzodiazepines; Databases, Factual; Drug Prescriptions; Fentanyl; Humans

2018
CE: Original Research: The Efficacy and Safety of an RN-Driven Ketamine Protocol for Adjunctive Analgesia During Burn Wound Care.
    The American journal of nursing, 2018, Volume: 118, Issue:7

    Topics: Adult; Analgesia; Analgesics; Analgesics, Opioid; Burns; Critical Care Nursing; Female; Fentanyl; Hu

2018
Antiallodynic and Antihyperalgesic Activities of Fentanyl-Loaded Dermal Clay Dressings in Rat Model of Second-Degree Burn Injury.
    Journal of pharmaceutical sciences, 2018, Volume: 107, Issue:10

    Topics: Animals; Bandages; Burns; Clay; Disease Models, Animal; Fentanyl; Hyperalgesia; Male; Pain; Rats; Ra

2018
Transition From Continuous Infusion Fentanyl to Hydromorphone in Critically Ill Patients.
    Journal of pharmacy practice, 2020, Volume: 33, Issue:2

    Topics: Adult; Analgesics, Opioid; Critical Care; Critical Illness; Female; Fentanyl; Humans; Hydromorphone;

2020
Parenteral Opioid Shortage - Treating Pain during the Opioid-Overdose Epidemic.
    The New England journal of medicine, 2018, Aug-16, Volume: 379, Issue:7

    Topics: Administration, Intravenous; Analgesics, Opioid; Drug Compounding; Drug Overdose; Fentanyl; Governme

2018
Association between the rs7583431 single nucleotide polymorphism close to the activating transcription factor 2 gene and the analgesic effect of fentanyl in the cold pain test.
    Neuropsychopharmacology reports, 2018, Volume: 38, Issue:2

    Topics: Activating Transcription Factor 2; Adolescent; Adult; Analgesics, Opioid; Cold Temperature; Drug Res

2018
Opioid Prescribing Behavior in Long-Term Geriatric Care in the Netherlands.
    Journal of the American Medical Directors Association, 2018, Volume: 19, Issue:11

    Topics: Adult; Aged; Analgesics, Opioid; Cross-Sectional Studies; Drug Prescriptions; Female; Fentanyl; Geri

2018
Opioid Induced Hyperalgesia with Intrathecal Infusion of High-Dose Fentanyl.
    Pain practice : the official journal of World Institute of Pain, 2019, Volume: 19, Issue:2

    Topics: Analgesics, Opioid; Bupivacaine; Female; Fentanyl; Humans; Hyperalgesia; Infusion Pumps, Implantable

2019
Taking the pain by the horns: rams and measuring tape.
    Minerva anestesiologica, 2018, Volume: 84, Issue:12

    Topics: Analgesia; Animals; Craniotomy; Fentanyl; Humans; Male; Nociception; Pain; Scalp; Sheep

2018
Characterization of the antinociceptive effects of intrathecal DALDA peptides following bolus intrathecal delivery.
    Scandinavian journal of pain, 2019, 01-28, Volume: 19, Issue:1

    Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Escape Reaction; Fentanyl; Injections

2019
Assessment of prior opioid tolerance among new users of fentanyl transdermal system in FDA's Sentinel System.
    Pharmacoepidemiology and drug safety, 2019, Volume: 28, Issue:1

    Topics: Administration, Cutaneous; Adolescent; Adult; Analgesics, Opioid; Child; Child, Preschool; Delayed-A

2019
A population-based study of transdermal fentanyl initiation in Australian clinical practice.
    European journal of clinical pharmacology, 2019, Volume: 75, Issue:3

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Australia

2019
Trends in the consumption of opioids for the treatment of severe pain in Europe, 1990-2016.
    European journal of pain (London, England), 2019, Volume: 23, Issue:4

    Topics: Analgesics, Opioid; Europe; European Union; Fentanyl; Humans; Hydromorphone; Meperidine; Morphine; O

2019
Patterns and history of prescription drug use among opioid-related drug overdose cases in British Columbia, Canada, 2015-2016.
    Drug and alcohol dependence, 2019, 01-01, Volume: 194

    Topics: Adult; Analgesics, Opioid; British Columbia; Case-Control Studies; Drug Overdose; Female; Fentanyl;

2019
Comparison of the use of different analgesics in the course of anesthesia care based on pharmacoeconomics.
    Pakistan journal of pharmaceutical sciences, 2018, Volume: 31, Issue:5(Special)

    Topics: Analgesics; Anesthesia; Delayed-Action Preparations; Economics, Pharmaceutical; Fentanyl; Humans; Mo

2018
Effectiveness of premedication protocol using intravenous fentanyl to reduce pain associated with femoral artery closure device placement.
    Clinical radiology, 2019, Volume: 74, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Endovascular Procedures; Equipment and Supplies;

2019
Unusual case of transdermal fentanyl in cachexia.
    BMJ supportive & palliative care, 2019, Volume: 9, Issue:4

    Topics: Analgesics, Opioid; Cachexia; Female; Fentanyl; Hospices; Humans; Middle Aged; Naloxone; Narcotic An

2019
Phosphorylation-deficient G-protein-biased μ-opioid receptors improve analgesia and diminish tolerance but worsen opioid side effects.
    Nature communications, 2019, 01-21, Volume: 10, Issue:1

    Topics: Analgesia; Analgesics, Opioid; Animals; beta-Arrestins; Brain; Drug Tolerance; Female; Fentanyl; Gen

2019
Differences in pain treatment between surgeons and anaesthesiologists in a physician staffed prehospital emergency medical service: a retrospective cohort analysis.
    BMC anesthesiology, 2019, 01-31, Volume: 19, Issue:1

    Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Anesthesiologists; Cohort Studies; Emergency Medical Se

2019
Clinical and Economic Analysis of Morphine Versus Fentanyl in Managing Ventilated Neonates With Respiratory Distress Syndrome in the Intensive Care Setting.
    Clinical therapeutics, 2019, Volume: 41, Issue:4

    Topics: Analgesia; Analgesics, Opioid; Cost-Benefit Analysis; Female; Fentanyl; Humans; Infant, Newborn; Inf

2019
Challenges of Remote Medical Care in South Sudan: Centipede Bites.
    Wilderness & environmental medicine, 2019, Volume: 30, Issue:2

    Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Animals; Anti-Inflammatory Agents; Arthropod Venoms;

2019
Evaluation of soluble fentanyl microneedles for loco-regional anti-nociceptive activity.
    International journal of pharmaceutics, 2019, Jun-10, Volume: 564

    Topics: Analgesics, Opioid; Animals; Drug Liberation; Fentanyl; Male; Microinjections; Needles; Pain; Rats,

2019
No Fever, No Murmur, No Problem? A Concealed Case of Infective Endocarditis.
    The Journal of emergency medicine, 2019, Volume: 57, Issue:2

    Topics: Adult; Amphetamine; Analgesics, Opioid; Anti-Bacterial Agents; C-Reactive Protein; Endocarditis; Eno

2019
Comparison of the Effects of Midazolam/Fentanyl, Midazolam/Propofol, and Midazolam/Fentanyl/Propofol on Cognitive Function After Gastrointestinal Endoscopy.
    Surgical laparoscopy, endoscopy & percutaneous techniques, 2019, Volume: 29, Issue:6

    Topics: Analgesics, Opioid; Cognition; Drug Therapy, Combination; Endoscopy, Gastrointestinal; Female; Fenta

2019
Current practice and perceptions regarding pain, agitation and delirium management in patients receiving venovenous extracorporeal membrane oxygenation.
    Journal of critical care, 2019, Volume: 53

    Topics: Adult; Analgesics, Opioid; Anesthesia; Anesthetics, Intravenous; Attitude of Health Personnel; Benzo

2019
MULTIMODAL LOW-OPIOID ANESTHESIA - A NEW APPROACH TO THE ISSUE OF ADEQUATE INTRAOPERATIVE ANALGESIA.
    Georgian medical news, 2019, Issue:289

    Topics: Aged; Analgesia; Analgesics, Opioid; Anesthesiology; Child; Child, Preschool; Fentanyl; Humans; Pain

2019
A comparison of the antinociceptive and temperature responses to morphine and fentanyl derivatives in rats.
    Archives of pharmacal research, 2013, Volume: 36, Issue:4

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Body Temperature; Disease Models, Animal; Dose-Respon

2013
Development of federally mandated risk evaluation and mitigation strategies (REMS) for transmucosal immediate-release fentanyl products.
    Pain practice : the official journal of World Institute of Pain, 2013, Volume: 13, Issue:4

    Topics: Administration, Mucosal; Analgesics, Opioid; Fentanyl; Humans; Pain; Pharmacovigilance; Risk Managem

2013
Long-term analysis of Irukandji stings in Far North Queensland.
    Diving and hyperbaric medicine, 2013, Volume: 43, Issue:1

    Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Animals; Bathing Beaches; Bites and Stings; Child; Chil

2013
A serious threat to patient safety: the unintended misuse of FentaNYL patches.
    Journal of emergency nursing, 2013, Volume: 39, Issue:3

    Topics: Administration, Cutaneous; Aged; Analgesics, Opioid; Child, Preschool; Fatal Outcome; Female; Fentan

2013
Pre- and post-intervention study to assess the impact of a sedation protocol in critically ill surgical patients.
    The Journal of surgical research, 2013, Volume: 184, Issue:2

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Benzodiazepines; Cohort Studies; Critical Care; Critica

2013
Treating pain in newborn infants: navigating between Scylla and Charybdis.
    The Journal of pediatrics, 2013, Volume: 163, Issue:3

    Topics: Analgesics, Opioid; Female; Fentanyl; Humans; Infant, Premature, Diseases; Male; Pain; Respiration,

2013
[Fentanyl: fast and furious?].
    Der Anaesthesist, 2013, Volume: 62, Issue:6

    Topics: Analgesics, Opioid; Breakthrough Pain; Fentanyl; Humans; Neoplasms; Pain; Pain, Intractable

2013
Fentanyl utility function: a risk-benefit composite of pain relief and breathing responses.
    Anesthesiology, 2013, Volume: 119, Issue:3

    Topics: Adult; Analgesics, Opioid; Computer Simulation; Fentanyl; Humans; Injections, Intravenous; Male; Pai

2013
Assessing the utility of the utility function.
    Anesthesiology, 2013, Volume: 119, Issue:3

    Topics: Analgesics, Opioid; Fentanyl; Humans; Male; Pain; Respiration

2013
Gene polymorphisms of OPRM1 A118G and ABCB1 C3435T may influence opioid requirements in Chinese patients with cancer pain.
    Asian Pacific journal of cancer prevention : APJCP, 2013, Volume: 14, Issue:5

    Topics: Aged; Analgesics, Opioid; ATP Binding Cassette Transporter, Subfamily B; Base Sequence; China; Femal

2013
Sedation for interventional gastrointestinal endoscopic procedures: are we overlooking the “pain”?
    Surgical endoscopy, 2014, Volume: 28, Issue:1

    Topics: Analgesia; Analgesics; Anesthetics, Combined; Endoscopy, Gastrointestinal; Female; Fentanyl; Gallsto

2014
Utilization of fentanyl buccal tablets in England: exploring off-label use reported in a cohort study.
    European journal of pain (London, England), 2014, Volume: 18, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Cohort Studies; England; Female; Fen

2014
Differential alternation of the antinociceptive effect of narcotic analgesics on the inflammatory pain state.
    Neuroscience letters, 2014, Feb-07, Volume: 560

    Topics: Animals; Fentanyl; Freund's Adjuvant; Hyperalgesia; Inflammation; Male; Methadone; Mice; Narcotics;

2014
Pain control in patients with hepatocellular carcinoma treated by percutaneous radiofrequency ablation: comparison of the efficacy of one-shot and continuous intravenous fentanyl delivery.
    Acta radiologica (Stockholm, Sweden : 1987), 2014, Volume: 55, Issue:10

    Topics: Aged; Anesthetics, Intravenous; Carcinoma, Hepatocellular; Catheter Ablation; Female; Fentanyl; Huma

2014
Is there an alternative to continuous opioid infusion for neonatal pain control? A preliminary report of parent/nurse-controlled analgesia in the neonatal intensive care unit.
    Paediatric anaesthesia, 2014, Volume: 24, Issue:4

    Topics: Age Distribution; Analgesics, Opioid; Female; Fentanyl; Gestational Age; Humans; Infant; Infant, New

2014
Genetic, pathological and physiological determinants of transdermal fentanyl pharmacokinetics in 620 cancer patients of the EPOS study.
    Pharmacogenetics and genomics, 2014, Volume: 24, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; ATP Binding Cassette Transporter, Subfamily D, M

2014
What is your gut feeling about opioid rotation?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Jan-20, Volume: 33, Issue:3

    Topics: Administration, Cutaneous; Administration, Oral; Analgesics, Opioid; Biological Availability; Delaye

2015
In vivo profiling of seven common opioids for antinociception, constipation and respiratory depression: no two opioids have the same profile.
    British journal of pharmacology, 2015, Volume: 172, Issue:2

    Topics: Analgesics, Opioid; Animals; Benzeneacetamides; Buprenorphine; Castor Oil; Constipation; Diarrhea; E

2015
Glasgow Coma Scores, early opioids, and posttraumatic stress disorder among combat amputees.
    Journal of traumatic stress, 2014, Volume: 27, Issue:2

    Topics: Afghan Campaign 2001-; Amnesia; Amputees; Analgesics, Opioid; Comorbidity; Drug Therapy, Combination

2014
Effect of intravenous general anaesthesia with epidural block on the expression of pre-endogenous opioid peptide genes.
    The Journal of international medical research, 2014, Volume: 42, Issue:3

    Topics: Abdomen; Adult; Anesthesia, Epidural; Anesthesia, General; Anesthetics, Intravenous; beta-Endorphin;

2014
Changes in trends and pattern of strong opioid prescribing in primary care.
    European journal of pain (London, England), 2014, Volume: 18, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Buprenorphine; Cross-Sectional Studi

2014
Step-up testing procedure for multiple comparisons with a control for a latent variable model with ordered categorical responses.
    Statistics in medicine, 2014, Sep-20, Volume: 33, Issue:21

    Topics: Algorithms; Clinical Trials as Topic; Computer Simulation; Data Interpretation, Statistical; Fentany

2014
[Use of fendivia transdermal therapeutic system in Russian patients with malignant neoplasms during palliative care: pharmacoeconomic aspects].
    Terapevticheskii arkhiv, 2014, Volume: 86, Issue:2

    Topics: Ambulances; Analgesics, Opioid; Cost-Benefit Analysis; Economics, Pharmaceutical; Fentanyl; Health C

2014
Development, validation and application of an HPLC-MS/MS method for the determination of fentanyl and nor-fentanyl in human plasma and saliva.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2014, Jun-01, Volume: 960

    Topics: Chromatography, High Pressure Liquid; Drug Monitoring; Drug Stability; Fentanyl; Humans; Linear Mode

2014
Chronopharmacology of analgesic effect and tolerance induced by six narcotic analgesics in mice.
    Drug research, 2015, Volume: 65, Issue:3

    Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Female; Fentanyl; Mic

2015
A retrospective study on the influence of nutritional status on pain management in cancer patients using the transdermal fentanyl patch.
    Biological & pharmaceutical bulletin, 2014, Volume: 37, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Female; Fentanyl; Humans; Male; Middle Aged; Neo

2014
Transdermal fentanyl for pain due to chemoradiotherapy-induced oral mucositis in nasopharyngeal cancer patients: evaluating efficacy, safety, and improvement in quality of life.
    Drug design, development and therapy, 2014, Volume: 8

    Topics: Administration, Cutaneous; Adult; Carcinoma; Chemoradiotherapy; Female; Fentanyl; Humans; Male; Midd

2014
Aerosol-stable peptide-coated liposome nanoparticles: a proof-of-concept study with opioid fentanyl in enhancing analgesic effects and reducing plasma drug exposure.
    Journal of pharmaceutical sciences, 2014, Volume: 103, Issue:8

    Topics: Acylation; Aerosols; Analgesics, Opioid; Animals; Central Nervous System; Fentanyl; Human Umbilical

2014
Medication errors related to transdermal opioid patches: lessons from a regional incident reporting system.
    BMC pharmacology & toxicology, 2014, Jun-09, Volume: 15

    Topics: Adverse Drug Reaction Reporting Systems; Analgesics, Opioid; Buprenorphine; Fentanyl; Humans; Medica

2014
Dissociation of immunosuppressive and nociceptive effects of fentanyl, but not morphine, after repeated administration in mice: fentanyl-induced sensitization to LPS.
    Brain, behavior, and immunity, 2014, Volume: 42

    Topics: Analgesics; Animals; Fentanyl; Immunosuppressive Agents; Lipopolysaccharides; Male; Mice; Morphine;

2014
[Dynamics of indices of sympatho-adrenal system at application of a combined central sedation using alpha2a-NMDA and phentanyl].
    Klinichna khirurhiia, 2014, Issue:4

    Topics: Anesthesia, General; Anesthetics, Intravenous; Breast Neoplasms; Epinephrine; Female; Fentanyl; Huma

2014
Increasing use of opioids for pain.
    European journal of pain (London, England), 2014, Volume: 18, Issue:9

    Topics: Analgesics, Opioid; Buprenorphine; Drug Prescriptions; Female; Fentanyl; Humans; Male; Morphine; Oxy

2014
Relationship between onset of pain relief and patient satisfaction with fentanyl pectin nasal spray for breakthrough pain in cancer.
    Journal of palliative medicine, 2014, Volume: 17, Issue:10

    Topics: Administration, Intranasal; Analgesics, Opioid; Double-Blind Method; Female; Fentanyl; Humans; Male;

2014
Frequent use of opioids in patients with dementia and nursing home residents: A study of the entire elderly population of Denmark.
    Alzheimer's & dementia : the journal of the Alzheimer's Association, 2015, Volume: 11, Issue:6

    Topics: Age Factors; Aged; Aged, 80 and over; Analgesics, Opioid; Buprenorphine; Comorbidity; Cross-Sectiona

2015
Opioid Concentrations in Oral Fluid and Plasma in Cancer Patients With Pain.
    Journal of pain and symptom management, 2015, Volume: 50, Issue:4

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Analgesics, Opioid; Blood Chemical Ana

2015
Interaction of the adenosine A1 receptor agonist N6-cyclopentyladenosine and κ-opioid receptors in rat spinal cord nociceptive reflexes.
    Behavioural pharmacology, 2014, Volume: 25, Issue:8

    Topics: Adenosine; Animals; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Inte

2014
Haplotypes of P2RX7 gene polymorphisms are associated with both cold pain sensitivity and analgesic effect of fentanyl.
    Molecular pain, 2014, Dec-03, Volume: 10

    Topics: Adult; Analgesics; Cations; Cold Temperature; Female; Fentanyl; Gene Frequency; Genotype; Haplotypes

2014
Clofarabine-based combination chemotherapy for relapse and refractory childhood acute lymphoblastic leukemia.
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2014, Volume: 55, Issue:11

    Topics: Adenine Nucleotides; Adolescent; Analgesics, Opioid; Antibiotic Prophylaxis; Antineoplastic Combined

2014
Patient-controlled intranasal fentanyl analgesia: a pilot study to assess practicality and tolerability during childbirth.
    International journal of obstetric anesthesia, 2015, Volume: 24, Issue:2

    Topics: Administration, Intranasal; Adolescent; Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; De

2015
Effect of premedication regimen on infant pain and stress response to endotracheal intubation.
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:6

    Topics: Analgesics, Opioid; Blood Glucose; Drug Combinations; Fentanyl; Gestational Age; Humans; Infant; Int

2015
The efficacy of low-dose transdermal fentanyl in opioid-naïve cancer patients with moderate-to-severe pain.
    The Korean journal of internal medicine, 2015, Volume: 30, Issue:1

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Female; Fentanyl; Hum

2015
Influence of serum albumin levels during opioid rotation from morphine or oxycodone to fentanyl for cancer pain.
    Biological & pharmaceutical bulletin, 2014, Volume: 37, Issue:12

    Topics: Analgesics, Opioid; Fentanyl; Humans; Morphine; Neoplasms; Oxycodone; Pain; Serum Albumin

2014
[A case of recurrent colon cancer with improvement in prognosis and cancer pain after surgical intervention].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2014, Volume: 41, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Fentanyl; Humans; Male; Middle Ag

2014
Expedited Delivery of Pain Medication for Long-Bone Fractures Using an Intranasal Fentanyl Clinical Pathway.
    Pediatric emergency care, 2015, Volume: 31, Issue:8

    Topics: Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Child, Preschool; Critical Pathwa

2015
Safety of deep sedation in young children with sickle cell disease: a retrospective cohort study.
    The Journal of pediatrics, 2015, Volume: 166, Issue:5

    Topics: Acute Chest Syndrome; Adjuvants, Anesthesia; Anemia, Sickle Cell; Child; Child, Preschool; Deep Seda

2015
Renal function and symptoms/adverse effects in opioid-treated patients with cancer.
    Acta anaesthesiologica Scandinavica, 2015, Volume: 59, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Cross-Sectional Studies; Fentanyl; G

2015
[Efficacy of a fentanyl citrate buccal tablet for esophageal cancer pain management in a patient unable to take oral medication].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:4

    Topics: Analgesics, Opioid; Carcinoma, Squamous Cell; Esophageal Neoplasms; Fatal Outcome; Fentanyl; Humans;

2015
Pain Control after Total Knee Arthroplasty: Comparing Intra-Articular Local Anesthetic Injection with Femoral Nerve Block.
    BioMed research international, 2015, Volume: 2015

    Topics: Aged; Anesthetics, Local; Arthroplasty, Replacement, Knee; Female; Femoral Nerve; Fentanyl; Humans;

2015
Fentanyl tolerance in the treatment of cancer pain: a case of successful opioid switching from fentanyl to oxycodone at a reduced equivalent dose.
    Journal of pain & palliative care pharmacotherapy, 2015, Volume: 29, Issue:2

    Topics: Analgesics, Opioid; Drug Substitution; Fentanyl; Humans; Male; Middle Aged; Oxycodone; Pain; Pain Ma

2015
Synthesis of Carfentanil Amide Opioids Using the Ugi Multicomponent Reaction.
    ACS chemical neuroscience, 2015, Sep-16, Volume: 6, Issue:9

    Topics: Amides; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical;

2015
Does intranasal fentanyl provide efficient analgesia for renal colic in adults?
    The Pan African medical journal, 2015, Volume: 20

    Topics: Administration, Intranasal; Adult; Aged; Analgesics, Opioid; Dose-Response Relationship, Drug; Emerg

2015
Innate Immune Signalling Genetics of Pain, Cognitive Dysfunction and Sickness Symptoms in Cancer Pain Patients Treated with Transdermal Fentanyl.
    PloS one, 2015, Volume: 10, Issue:9

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Cognition Disorders;

2015
Accuracy of using Diagnosis Procedure Combination administrative claims data for estimating the amount of opioid consumption among cancer patients in Japan.
    Japanese journal of clinical oncology, 2015, Volume: 45, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Codeine; Drug Prescriptions; Female; Fentanyl; H

2015
Pain management during radiotherapy and radiochemotherapy in oropharyngeal cancer patients: single-institution experience.
    International dental journal, 2015, Volume: 65, Issue:5

    Topics: Acetaminophen; Adult; Aged; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal;

2015
Paravertebral block decreases opioid administration without causing hypotension during transapical transcatheter aortic valve implantation.
    Heart and vessels, 2016, Volume: 31, Issue:9

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anesthetics, Local; Aortic Valve; Blood Pressure; Bupiv

2016
Saliva versus Plasma for Pharmacokinetic and Pharmacodynamic Studies of Fentanyl in Patients with Cancer.
    Clinical therapeutics, 2015, Nov-01, Volume: 37, Issue:11

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Chromatography, High

2015
An Assessment of Newly Identified Barriers to and Enablers for Prehospital Pediatric Pain Management.
    Pediatric emergency care, 2017, Volume: 33, Issue:6

    Topics: Administration, Intranasal; Administration, Intravenous; Adult; Allied Health Personnel; Analgesics;

2017
Analgesic effect and pharmacological mechanism of fentanyl and butorphanol in a rat model of incisional pain.
    Journal of clinical anesthesia, 2016, Volume: 28

    Topics: Analgesics, Opioid; Animals; Butorphanol; Dose-Response Relationship, Drug; Drug Therapy, Combinatio

2016
The opioid rotation ratio of strong opioids to transdermal fentanyl in cancer patients.
    Cancer, 2016, Jan-01, Volume: 122, Issue:1

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Drug Admi

2016
Time to opioid administration after implementation of an intranasal fentanyl protocol.
    The American journal of emergency medicine, 2015, Volume: 33, Issue:12

    Topics: Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Child, Preschool; Clinical Protoc

2015
Saliva versus Plasma for Pharmacokinetic and Pharmacodynamic Studies of Fentanyl in Patients with Cancer.
    Clinical therapeutics, 2015, Dec-01, Volume: 37, Issue:12

    Topics: Analgesics, Opioid; Female; Fentanyl; Humans; Male; Pain; Saliva

2015
Saliva versus Plasma for Pharmacokinetic and Pharmacodynamic Studies of Fentanyl in Patients with Cancer.
    Clinical therapeutics, 2015, Dec-01, Volume: 37, Issue:12

    Topics: Analgesics, Opioid; Female; Fentanyl; Humans; Male; Pain; Saliva

2015
Fentanyl-Induced Neurotoxicity in Children.
    Journal of pain & palliative care pharmacotherapy, 2015, Volume: 29, Issue:4

    Topics: Akathisia, Drug-Induced; Analgesics, Opioid; Child; Female; Fentanyl; Hallucinations; Headache; Huma

2015
Response to intravenous fentanyl infusion predicts subsequent response to transdermal fentanyl.
    Journal of anesthesia, 2016, Volume: 30, Issue:2

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Female; Fentanyl; Hum

2016
[Transdermal System-Buprenorphine and Fentanyl].
    Masui. The Japanese journal of anesthesiology, 2015, Volume: 64, Issue:11

    Topics: Analgesics, Opioid; Buprenorphine; Clinical Trials as Topic; Fentanyl; Humans; Pain; Pain Management

2015
[Understanding Oral and Nasal Mucosal Absorption of Fentanyl, and Rectal Absorption of Buprenorphine].
    Masui. The Japanese journal of anesthesiology, 2015, Volume: 64, Issue:11

    Topics: Administration, Mucosal; Administration, Oral; Analgesics, Opioid; Buprenorphine; Fentanyl; Humans;

2015
Consequences of unsafe prescribing of transdermal fentanyl.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, 06-14, Volume: 188, Issue:9

    Topics: Administration, Cutaneous; Analgesics, Opioid; Fentanyl; Humans; Neoplasms; Pain

2016
[Use of Transdermal Fentanyl in a Hospital].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:3

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Female; Fentanyl; Hum

2016
A two-year retrospective review of the determinants of pre-hospital analgesia administration by alpine helicopter emergency medical physicians to patients with isolated limb injury.
    Anaesthesia, 2016, Volume: 71, Issue:7

    Topics: Adult; Air Ambulances; Analgesia; Analgesics; Analgesics, Opioid; Emergency Medical Services; Female

2016
Are transdermal opioids contraindicated in patients at risk of suicide?
    European journal of anaesthesiology, 2017, Volume: 34, Issue:1

    Topics: Administration, Cutaneous; Analgesics, Opioid; Fentanyl; Humans; Pain; Suicide

2017
Reply to: are transdermal opioids contraindicated in patients at risk of suicide?
    European journal of anaesthesiology, 2017, Volume: 34, Issue:1

    Topics: Administration, Cutaneous; Analgesics, Opioid; Fentanyl; Humans; Pain; Suicide

2017
Endogenous opioidergic dysregulation of pain in fibromyalgia: a PET and fMRI study.
    Pain, 2016, Volume: 157, Issue:10

    Topics: Adolescent; Adult; Aged; Brain; Brain Mapping; Female; Fentanyl; Fibromyalgia; Humans; Image Process

2016
[Interaction of opioid analgesics at the level of biotransformation].
    Schmerz (Berlin, Germany), 2016, Volume: 30, Issue:6

    Topics: Aged; Analgesics, Opioid; Biotransformation; Codeine; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3

2016
Breakthrough pain: just pain?
    Pain, 2016, Volume: 157, Issue:12

    Topics: Analgesics, Opioid; Breakthrough Pain; Fentanyl; Humans; Neoplasms; Pain; Pain Measurement

2016
Emergency Department Pain Management in Adult Patients With Traumatic Injuries Before and After Implementation of a Nurse-Initiated Pain Treatment Protocol Utilizing Fentanyl for Severe Pain.
    The Journal of emergency medicine, 2017, Volume: 52, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Emergency Service, Hospital; Female; Fentany

2017
Dose and Duration of Opioid Use in Patients with Cancer and Noncancer Pain at an Outpatient Hospital Setting in Malaysia.
    Pain practice : the official journal of World Institute of Pain, 2017, Volume: 17, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Cancer Pain; Cross-Sectional Studies

2017
Letter response: Methadone is superior to fentanyl in treating neuropathic pain in patients with head-and-neck cancer.
    European journal of cancer (Oxford, England : 1990), 2016, Volume: 68

    Topics: Analgesics, Opioid; Fentanyl; Head and Neck Neoplasms; Humans; Methadone; Neuralgia; Pain; Pain Meas

2016
Methadone is superior to fentanyl in treating neuropathic pain in patients with head-and-neck cancer.
    European journal of cancer (Oxford, England : 1990), 2016, Volume: 68

    Topics: Analgesics, Opioid; Fentanyl; Head and Neck Neoplasms; Humans; Methadone; Neoplasms; Neuralgia; Pain

2016
Prolonged thoracic epidural analgesia for chest tube pain during pregnancy.
    International journal of obstetric anesthesia, 2017, Volume: 30

    Topics: Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; B

2017
A retrospective analysis of nebulized versus intravenous fentanyl for renal colic.
    The American journal of emergency medicine, 2017, Volume: 35, Issue:5

    Topics: Administration, Inhalation; Administration, Intravenous; Adult; Analgesics, Opioid; Double-Blind Met

2017
Intranasal fentanyl and inhaled nitrous oxide for fracture reduction: The FAN observational study.
    The American journal of emergency medicine, 2017, Volume: 35, Issue:5

    Topics: Adolescent; Analgesia; Anesthetics, Inhalation; Anxiety; Australia; Canada; Child; Child, Preschool;

2017
Current Concepts of Phenylpiperidine Derivatives Use in the Treatment of Acute and Chronic Pain.
    Pain physician, 2017, Volume: 20, Issue:2S

    Topics: Analgesics; Chronic Pain; Fentanyl; Humans; Pain; Piperidines; Sufentanil

2017
[Measurement of amount of fentanyl remaining in used patches: investigation of clinical factors affecting the remaining amounts in 4 patients].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2008, Volume: 128, Issue:6

    Topics: Administration, Cutaneous; Aged; Analgesics, Opioid; Body Mass Index; Dosage Forms; Female; Fentanyl

2008
[Patient-controlled analgesia with iontophoretic fentanyl].
    Medizinische Monatsschrift fur Pharmazeuten, 2008, Volume: 31, Issue:5

    Topics: Administration, Cutaneous; Analgesia, Patient-Controlled; Analgesics, Opioid; Fentanyl; Humans; Iont

2008
New protocol in NY.
    JEMS : a journal of emergency medical services, 2008, Volume: 33, Issue:7

    Topics: Analgesics, Opioid; Clinical Protocols; Emergency Medical Services; Evidence-Based Medicine; Fentany

2008
Fentanyl patch for stable chronic pain in children: new indication. Used fentanyl patches should be handled with care.
    Prescrire international, 2008, Volume: 17, Issue:95

    Topics: Administration, Cutaneous; Adolescent; Analgesics, Opioid; Child; Child, Preschool; Chronic Disease;

2008
Involvement of kappa-opioid receptors in visceral nociception in mice.
    Neurogastroenterology and motility, 2008, Volume: 20, Issue:10

    Topics: Analgesics, Opioid; Animals; Colon; Dilatation, Pathologic; Electromyography; Female; Fentanyl; Huma

2008
[Perioperative management of patients with cancer-pain receiving fentanyl patch].
    Masui. The Japanese journal of anesthesiology, 2008, Volume: 57, Issue:7

    Topics: Administration, Cutaneous; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, General; F

2008
Fentanyl transdermal matrix patch (Durotep MT patch; Durogesic DTrans; Durogesic SMAT): in adults with cancer-related pain.
    Drugs, 2008, Volume: 68, Issue:12

    Topics: Administration, Cutaneous; Adult; Analgesics, Opioid; Area Under Curve; Clinical Trials, Phase II as

2008
Analgesic activity and pharmacological characterization of N-[1-phenylpyrazol-3-yl]-N-[1-(2-phenethyl)-4-piperidyl] propenamide, a new opioid agonist acting peripherally.
    European journal of pharmacology, 2008, Oct-24, Volume: 595, Issue:1-3

    Topics: Administration, Oral; Analgesics, Opioid; Animals; Disease Models, Animal; Dose-Response Relationshi

2008
Oxycodone-induced analgesic effects in a bone cancer pain model in mice.
    Oncology, 2008, Volume: 74 Suppl 1

    Topics: Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Bone Neoplasms; Disease Models, Animal; F

2008
Using pain relief patches safely.
    The Johns Hopkins medical letter health after 50, 2008, Volume: 20, Issue:4

    Topics: Analgesics, Opioid; Drug Delivery Systems; Fentanyl; Humans; Pain; Safety

2008
[Medicinal management of pain and symptoms following the withdrawal of treatment in babies and children].
    Nederlands tijdschrift voor geneeskunde, 2008, Sep-20, Volume: 152, Issue:38

    Topics: Female; Fentanyl; Humans; Infant; Infant, Newborn; Life Support Care; Neuromuscular Agents; Neuromus

2008
[Analgesics and palliative care].
    Revue medicale de Bruxelles, 2008, Volume: 29, Issue:4

    Topics: Analgesics; Analgesics, Opioid; Fentanyl; Humans; Methadone; Morphine; Neoplasms; Pain; Palliative C

2008
Commentary on Dr. Heit and Dr. Gilson's letter to the Drug Enforcement Administration. Does your pharmacist interpret a new federal standard in a manner that can make your patient suffer in pain?
    Pain medicine (Malden, Mass.), 2008, Volume: 9, Issue:7

    Topics: Fentanyl; Government Regulation; Humans; Legislation, Drug; Medical Errors; Pain; Prescription Drugs

2008
Role of delta opioid efficacy as a determinant of mu/delta opioid interactions in rhesus monkeys.
    European journal of pharmacology, 2009, Jan-05, Volume: 602, Issue:1

    Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Interactions; Fentanyl; Hot Temp

2009
Breakthrough cancer pain.
    BMJ (Clinical research ed.), 2008, Nov-25, Volume: 337

    Topics: Analgesics, Opioid; Fentanyl; Humans; Morphine; Neoplasms; Pain

2008
Safety alert for fentanyl buccal tablets.
    Journal of pain & palliative care pharmacotherapy, 2008, Volume: 22, Issue:1

    Topics: Administration, Buccal; Adverse Drug Reaction Reporting Systems; Analgesics, Opioid; Fentanyl; Human

2008
Trends in opioid consumption in the Nordic countries 2002-2006.
    European journal of pain (London, England), 2009, Volume: 13, Issue:9

    Topics: Analgesics, Opioid; Databases, Factual; Denmark; Dextropropoxyphene; Drug Administration Routes; Dru

2009
Equipotent doses to switch from high doses of opioids to transdermal buprenorphine.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2009, Volume: 17, Issue:6

    Topics: Administration, Cutaneous; Aged; Analgesics, Opioid; Buprenorphine; Dose-Response Relationship, Drug

2009
Comparative review of the clinical use of intranasal fentanyl versus morphine in a paediatric emergency department.
    Emergency medicine Australasia : EMA, 2008, Volume: 20, Issue:6

    Topics: Abdominal Pain; Administration, Intranasal; Analgesics, Opioid; Arm Injuries; Child; Child, Preschoo

2008
Comparative review of the clinical use of intranasal fentanyl versus morphine in a paediatric emergency department.
    Emergency medicine Australasia : EMA, 2008, Volume: 20, Issue:6

    Topics: Abdominal Pain; Administration, Intranasal; Analgesics, Opioid; Arm Injuries; Child; Child, Preschoo

2008
Comparative review of the clinical use of intranasal fentanyl versus morphine in a paediatric emergency department.
    Emergency medicine Australasia : EMA, 2008, Volume: 20, Issue:6

    Topics: Abdominal Pain; Administration, Intranasal; Analgesics, Opioid; Arm Injuries; Child; Child, Preschoo

2008
Comparative review of the clinical use of intranasal fentanyl versus morphine in a paediatric emergency department.
    Emergency medicine Australasia : EMA, 2008, Volume: 20, Issue:6

    Topics: Abdominal Pain; Administration, Intranasal; Analgesics, Opioid; Arm Injuries; Child; Child, Preschoo

2008
Lollipops & lawsuits.
    Newsweek, 2007, May-07, Volume: 149, Issue:19

    Topics: Analgesics, Opioid; Drug Labeling; Fentanyl; Humans; Marketing; Neoplasms; Pain; United States; Unit

2007
Factors in the choice of oral transmucosal fentanyl citrate dose for adult burns dressings.
    Burns : journal of the International Society for Burn Injuries, 2009, Volume: 35, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Aged; Analgesics, Opioid; Bandages; Burns; Choice Behavior;

2009
Sticking to the safe side with fentanyl patches.
    Nursing, 2009, Volume: 39, Issue:3

    Topics: Administration, Cutaneous; Analgesics, Opioid; Drug Overdose; Fentanyl; Humans; Pain; Patient Educat

2009
Safety of enteral naloxone for the reversal of opiate-induced constipation in the intensive care unit.
    Journal of clinical pharmacy and therapeutics, 2009, Volume: 34, Issue:2

    Topics: Aged; Analgesics, Opioid; Constipation; Critical Care; Female; Fentanyl; Humans; Intubation, Gastroi

2009
Safety of enteral naloxone for the reversal of opiate-induced constipation in the intensive care unit.
    Journal of clinical pharmacy and therapeutics, 2009, Volume: 34, Issue:2

    Topics: Aged; Analgesics, Opioid; Constipation; Critical Care; Female; Fentanyl; Humans; Intubation, Gastroi

2009
Safety of enteral naloxone for the reversal of opiate-induced constipation in the intensive care unit.
    Journal of clinical pharmacy and therapeutics, 2009, Volume: 34, Issue:2

    Topics: Aged; Analgesics, Opioid; Constipation; Critical Care; Female; Fentanyl; Humans; Intubation, Gastroi

2009
Safety of enteral naloxone for the reversal of opiate-induced constipation in the intensive care unit.
    Journal of clinical pharmacy and therapeutics, 2009, Volume: 34, Issue:2

    Topics: Aged; Analgesics, Opioid; Constipation; Critical Care; Female; Fentanyl; Humans; Intubation, Gastroi

2009
[Optimal conversion ratio of oral morphine to transdermal fentanyl patches to the cancer pain].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2009, Volume: 129, Issue:3

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics, Opioid;

2009
Prescription of opioids in Italy: everything, but the morphine.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2009, Volume: 20, Issue:5

    Topics: Administration, Cutaneous; Administration, Oral; Analgesics, Opioid; Buprenorphine; Drug and Narcoti

2009
Fentanyl transdermal analgesia during pregnancy and lactation.
    Journal of human lactation : official journal of International Lactation Consultant Association, 2009, Volume: 25, Issue:3

    Topics: Administration, Cutaneous; Adult; Analgesics, Opioid; Chronic Disease; Drug Residues; Female; Fentan

2009
The counteraction of opioid-induced ventilatory depression by the serotonin 1A-agonist 8-OH-DPAT does not antagonize antinociception in rats in situ and in vivo.
    Anesthesia and analgesia, 2009, Volume: 108, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesics, Opioid; Animals; Dose-Response Relationship, Dru

2009
Fentanyl in the out-of-hospital setting: variables associated with hypotension and hypoxemia.
    The Journal of emergency medicine, 2011, Volume: 40, Issue:2

    Topics: Adolescent; Adult; Aged; Air Ambulances; Analgesics, Opioid; Emergency Medical Services; Female; Fen

2011
Frequency, indications, outcomes, and predictive factors of opioid switching in an acute palliative care unit.
    Journal of pain and symptom management, 2009, Volume: 37, Issue:4

    Topics: Adult; Aged; Analgesics, Opioid; Buprenorphine; Female; Fentanyl; Humans; Male; Methadone; Middle Ag

2009
Secondary adrenal insufficiency due to opiate therapy - another differential diagnosis worth consideration.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2009, Volume: 117, Issue:10

    Topics: Adrenal Cortex Hormones; Adrenal Insufficiency; Analgesics, Opioid; Diagnosis, Differential; Fentany

2009
Identification of an additional supraspinal component to the analgesic mechanism of action of buprenorphine.
    British journal of pharmacology, 2009, Volume: 157, Issue:5

    Topics: Acetylcholine; Adrenergic alpha-Antagonists; Aminoquinolines; Analgesics, Opioid; Anesthetics, Local

2009
The feasibility of using intravenous fentanyl as sublingual drops in the treatment of incidental pain in patients with cancer.
    Journal of palliative medicine, 2009, Volume: 12, Issue:6

    Topics: Adult; Aged; Anesthetics, Intravenous; Feasibility Studies; Female; Fentanyl; Humans; Infusions, Int

2009
Acute and chronic fentanyl administration causes hyperalgesia independently of opioid receptor activity in mice.
    Neuroscience letters, 2009, Oct-02, Volume: 462, Issue:1

    Topics: Analysis of Variance; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Fentanyl; Hot

2009
Long-term pain vulnerability after surgery in rats: prevention by nefopam, an analgesic with antihyperalgesic properties.
    Anesthesia and analgesia, 2009, Volume: 109, Issue:2

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Carrageenan; Chronic Disease; Fentanyl; Hyper

2009
In brief: heat and transdermal fentanyl.
    The Medical letter on drugs and therapeutics, 2009, Aug-10, Volume: 51, Issue:1318

    Topics: Administration, Cutaneous; Analgesics, Opioid; Delayed-Action Preparations; Drug Overdose; Fentanyl;

2009
Magnesium modifies fentanyl-induced local antinociception and hyperalgesia.
    Naunyn-Schmiedeberg's archives of pharmacology, 2009, Volume: 380, Issue:5

    Topics: Analgesics, Opioid; Animals; Drug Interactions; Drug Synergism; Female; Fentanyl; Hot Temperature; H

2009
Morphine, oxycodone, and fentanyl exhibit different analgesic profiles in mouse pain models.
    Journal of pharmacological sciences, 2009, Volume: 111, Issue:1

    Topics: Analgesics; Animals; Behavior, Animal; Disease Models, Animal; Fentanyl; Male; Mice; Mice, Inbred C3

2009
The use of transdermal fentanyl in cancer pain--a compliance study of outpatients in Taiwan.
    The American journal of hospice & palliative care, 2010, Volume: 27, Issue:1

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Ambulatory Care; Analgesics, Opioid; Coho

2010
Positron emission tomography measures of endogenous opioid neurotransmission and impulsiveness traits in humans.
    Archives of general psychiatry, 2009, Volume: 66, Issue:10

    Topics: Adult; Brain; Carbon Radioisotopes; Emotions; Fentanyl; Humans; Individuality; Life Change Events; M

2009
Development of a liquid chromatography-isotope dilution mass spectrometry method for quantification of fentanyl in human plasma.
    Biomedical chromatography : BMC, 2010, Volume: 24, Issue:7

    Topics: Analgesics, Opioid; Chromatography, Liquid; Fentanyl; Humans; Pain; Tandem Mass Spectrometry

2010
[Fentanyl patch in the treatment of severe chronic pain].
    MMW Fortschritte der Medizin, 2009, Oct-01, Volume: 151, Issue:40

    Topics: Administration, Cutaneous; Analgesics, Opioid; Chronic Disease; Clinical Trials as Topic; Delayed-Ac

2009
Modification of fentanyl analgesia by antidepressants.
    Pharmacology, 2010, Volume: 85, Issue:1

    Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Drug Administration Schedule; Drug Interactions;

2010
Formulations of fentanyl for the management of pain.
    Drugs, 2010, Volume: 70, Issue:1

    Topics: Administration, Buccal; Administration, Cutaneous; Administration, Oral; Analgesia, Patient-Controll

2010
Effects of Parecoxib and Fentanyl on nociception-induced cortical activity.
    Molecular pain, 2010, Jan-21, Volume: 6

    Topics: Action Potentials; Analgesics, Opioid; Animals; Arousal; Cerebral Cortex; Cyclooxygenase 2 Inhibitor

2010
Fentanyl transdermal absorption linked to pharmacokinetic characteristics in patients undergoing palliative care.
    Journal of clinical pharmacology, 2010, Volume: 50, Issue:6

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Disease; Dose

2010
Transdermal fentanyl: not ready for front line.
    Journal of palliative care, 2009,Winter, Volume: 25, Issue:4

    Topics: Administration, Cutaneous; Analgesics, Opioid; Fentanyl; Humans; Meta-Analysis as Topic; Pain; Palli

2009
Does the standard intravenous solution of fentanyl (50 microg/mL) administered intranasally have analgesic efficacy?
    Emergency medicine Australasia : EMA, 2010, Volume: 22, Issue:1

    Topics: Administration, Intranasal; Adolescent; Analgesics, Opioid; Arm Injuries; Child; Child, Preschool; E

2010
Reducing patient harm with the use of fentanyl transdermal system.
    The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists, 2009, Volume: 24, Issue:12

    Topics: Administration, Cutaneous; Aged; Analgesics, Opioid; Fatal Outcome; Female; Fentanyl; Humans; Medica

2009
The dosing frequency of sustained-release opioids and the prevalence of end-of-dose failure in cancer pain control: a Korean multicenter study.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2010, Volume: 19, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Delayed-Action Preparations; Drug Administration

2010
Treating stridor with opioids: a challenging case of paradoxical vocal cord movement.
    Journal of clinical anesthesia, 2010, Volume: 22, Issue:2

    Topics: Analgesics, Opioid; Anesthesia, General; Female; Fentanyl; Humans; Laryngoscopy; Middle Aged; Pain;

2010
[Successful management of a patient with pain and dyspnea from bone metastasis and lymphangitis carcinomatosa after surgery for non-small cell lung cancer (NSCLC) in whom optimal dosages of transdermal fentanyl were determined by titration with fentanyl i
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:3

    Topics: Administration, Cutaneous; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Dyspnea; Female; Fentanyl

2010
Evaluation of analgesic effect and safety of fentanyl transdermal patch for cancer pain as the first line.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2010, Volume: 18, Issue:6

    Topics: Administration, Cutaneous; Aged; Analgesics, Opioid; Dose-Response Relationship, Drug; Female; Fenta

2010
Intranasal fentanyl for analgesia in the paediatric emergency department.
    Emergency medicine journal : EMJ, 2010, Volume: 27, Issue:4

    Topics: Administration, Intranasal; Adolescent; Analgesia; Analgesics, Opioid; Child; Child, Preschool; Emer

2010
The effect of treatment with fentanyl patches on pain relief and improvement in overall daily functioning in patients with postherpetic neuralgia.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2009, Volume: 60 Suppl 8

    Topics: Activities of Daily Living; Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Female; Fenta

2009
Fentanyl buccal soluble film (Onsolis) for breakthrough cancer pain.
    The Medical letter on drugs and therapeutics, 2010, Apr-19, Volume: 52, Issue:1336

    Topics: Administration, Buccal; Chemistry, Pharmaceutical; Cross-Over Studies; Double-Blind Method; Drug Tol

2010
[Drug safety problems in association with the use of opioid containing patches for the management of pain].
    Deutsche medizinische Wochenschrift (1946), 2010, Volume: 135, Issue:17

    Topics: Administration, Cutaneous; Adult; Aged, 80 and over; Analgesics, Opioid; Drug Overdose; Drug-Related

2010
Recent development in therapeutics for breakthrough pain.
    Expert review of neurotherapeutics, 2010, Volume: 10, Issue:5

    Topics: Administration, Buccal; Analgesics, Opioid; Drug Administration Routes; Fentanyl; Humans; Narcotics;

2010
Histamine H3 receptor activation potentiates peripheral opioid-mediated antinociception: substance P role in peripheral inflammation in mice.
    European journal of pharmacology, 2010, Jul-25, Volume: 638, Issue:1-3

    Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Fe

2010
[Home hospice care for the lung cancer patients].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36 Suppl 1

    Topics: Analgesics, Opioid; Dyspnea; Fentanyl; Home Care Services; Hospice Care; Humans; Lung Neoplasms; Mor

2009
A small, silent, low friction, linear actuator for mechanical nociceptive testing in veterinary research.
    Laboratory animals, 2010, Volume: 44, Issue:3

    Topics: Analgesics; Animals; Butorphanol; Cats; Dogs; Female; Fentanyl; Male; Pain; Pain Measurement; Pain T

2010
Inhaled methoxyflurane and intranasal fentanyl for prehospital management of visceral pain in an Australian ambulance service.
    Emergency medicine journal : EMJ, 2011, Volume: 28, Issue:1

    Topics: Administration, Inhalation; Administration, Intranasal; Adolescent; Adult; Aged; Ambulances; Analges

2011
Canadian neonatologist practices regarding opioid use in ventilated and spontaneously breathing infants undergoing medical procedures.
    The Clinical journal of pain, 2010, Volume: 26, Issue:5

    Topics: Analgesics, Opioid; Canada; Fentanyl; Health Care Surveys; Humans; Infant; Infant, Newborn; Morphine

2010
[Pain perception and pain therapy in premature infants].
    Kinderkrankenschwester : Organ der Sektion Kinderkrankenpflege, 2010, Volume: 29, Issue:5

    Topics: Acetaminophen; Age Factors; Analgesics, Non-Narcotic; Analgesics, Opioid; Fentanyl; Humans; Infant;

2010
The safety of flexible fibre-optic bronchoscopy and proceduralist-administered sedation: a tertiary referral centre experience.
    Internal medicine journal, 2012, Volume: 42, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biopsy; Bronchoscopy; Conscious Sedation; Dyspnea; Femal

2012
Biological rhythms of spinal-epidural labor analgesia.
    Chronobiology international, 2010, Volume: 27, Issue:4

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Analgesics, Opioi

2010
Historical perspectives and trends in the management of pain for cancer patients in oman.
    Asian Pacific journal of cancer prevention : APJCP, 2010, Volume: 11 Suppl 1

    Topics: Analgesics, Opioid; Fentanyl; Humans; Morphine; Neoplasms; Oman; Pain

2010
[Analgesic efficacy and tolerability of a generic fentanyl patch (TTS). Results of two post-marketing surveillance studies including 850 patients].
    MMW Fortschritte der Medizin, 2009, Volume: 151 Suppl 3

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Analgesics, Opioid; Chronic Disease; Dose-Respon

2009
Mechanically strong geopolymers offer new possibilities in treatment of chronic pain.
    Journal of controlled release : official journal of the Controlled Release Society, 2010, Sep-15, Volume: 146, Issue:3

    Topics: Analgesics, Opioid; Chronic Disease; Compressive Strength; Delayed-Action Preparations; Fentanyl; Hu

2010
The role of beta-arrestin2 in the severity of antinociceptive tolerance and physical dependence induced by different opioid pain therapeutics.
    Neuropharmacology, 2011, Volume: 60, Issue:1

    Topics: Analgesics, Opioid; Analysis of Variance; Animals; Arrestins; beta-Arrestins; Drug Tolerance; Fentan

2011
Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. BET 1: intranasal fentanyl or diamorphine versus intravenous morphine for analgesia in adults.
    Emergency medicine journal : EMJ, 2010, Volume: 27, Issue:9

    Topics: Administration, Intranasal; Adult; Analgesics, Opioid; Emergency Medicine; Evidence-Based Medicine;

2010
Fentanyl for breakthrough cancer pain--what's new?
    Pain, 2010, Volume: 151, Issue:3

    Topics: Analgesics, Opioid; Fentanyl; Humans; Neoplasms; Pain

2010
Suicide by Duragesic transdermal fentanyl patch toxicity.
    The American journal of emergency medicine, 2011, Volume: 29, Issue:1

    Topics: Adult; Analgesics, Opioid; Female; Fentanyl; Humans; Pain; Suicide; Transdermal Patch

2011
High-dose fentanyl patch for cancer pain of a patient with cholangiocarcinoma.
    The Korean journal of internal medicine, 2010, Volume: 25, Issue:3

    Topics: Administration, Cutaneous; Analgesics, Opioid; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cholan

2010
Case report. Intravenous fentanyl patient-controlled analgesia for perioperative treatment of neuropathic/ischaemic pain in haemodialysis patients: a case series.
    Journal of clinical pharmacy and therapeutics, 2010, Volume: 35, Issue:5

    Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Diabetic Neuropathies; Female; Fenta

2010
Inappropriate use of high doses of transdermal fentanyl at admission to a palliative care unit.
    Palliative medicine, 2011, Volume: 25, Issue:2

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics, Opioid;

2011
Transport mechanisms in oral transmucosal drug delivery: implications for pain management.
    Mathematical biosciences, 2011, Volume: 229, Issue:1

    Topics: Administration, Mucosal; Administration, Oral; Adult; Algorithms; Analgesics; Biological Availabilit

2011
p38 Mitogen-activated protein kinase activation by nerve growth factor in primary sensory neurons upregulates μ-opioid receptors to enhance opioid responsiveness toward better pain control.
    Anesthesiology, 2011, Volume: 114, Issue:1

    Topics: Analgesics, Opioid; Animals; Blotting, Western; Buprenorphine; Dose-Response Relationship, Drug; Dru

2011
Multi-centre European study of breakthrough cancer pain: pain characteristics and patient perceptions of current and potential management strategies.
    European journal of pain (London, England), 2011, Volume: 15, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Female; Fentanyl; Humans; Male; Middle Aged; Mor

2011
Fentanyl intranasal. Breakthrough cancer pain: unsafe packaging.
    Prescrire international, 2010, Volume: 19, Issue:110

    Topics: Administration, Intranasal; Analgesics, Opioid; Fentanyl; Humans; Neoplasms; Pain; Product Packaging

2010
Fentanyl-trazodone-paracetamol triple drug combination: multimodal analgesia in a mouse model of visceral pain.
    Pharmacology, biochemistry, and behavior, 2011, Volume: 98, Issue:3

    Topics: Acetaminophen; Analgesics; Animals; Disease Models, Animal; Drug Combinations; Fentanyl; Male; Mice;

2011
[A case of pain management using transdermal fentanyl patches for peritoneal carcinomatosis in a patient with small intestine stoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:2

    Topics: Administration, Cutaneous; Adult; Carcinoma; Fatal Outcome; Female; Fentanyl; Humans; Ileal Neoplasm

2011
Dose conversion in opioid rotation from continuous intravenous infusion of morphine hydrochloride injection to fentanyl patch in the management of cancer pain.
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2011, Volume: 131, Issue:3

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Drug Administration Schedule; Female; Fen

2011
Choosing the unit of measurement counts: the use of oral morphine equivalents in studies of opioid consumption is a useful addition to defined daily doses.
    Palliative medicine, 2011, Volume: 25, Issue:7

    Topics: Administration, Oral; Analgesics, Opioid; Cooperative Behavior; Databases, Factual; Drug Utilization

2011
[Direct low-dose fentanyl patch (2.1mg) introduction for opioid naïve outpatients with cancer pain].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Constipation; Female; Fentanyl; Humans; Male; Mi

2011
Acute leg pain due to iliac artery spasm during coronary angiography: an unusual consequence of an uncommon problem.
    Angiology, 2011, Volume: 62, Issue:4

    Topics: Acute Disease; Aged; Analgesics, Opioid; Coronary Angiography; Fentanyl; Humans; Iliac Artery; Leg;

2011
Factors predicting requirement of high-dose transdermal fentanyl in opioid switching from oral morphine or oxycodone in patients with cancer pain.
    The Clinical journal of pain, 2011, Volume: 27, Issue:8

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Child; Fe

2011
Three-cycle fentanyl patch system contributes to stable control of plasma fentanyl concentration in gynecologic cancer pain patients.
    Taiwanese journal of obstetrics & gynecology, 2011, Volume: 50, Issue:1

    Topics: Adenocarcinoma, Clear Cell; Administration, Cutaneous; Analgesics, Opioid; Carcinoma, Squamous Cell;

2011
Attitude and knowledge of physicians about cancer pain management: young doctors of South Korea in their early career.
    Japanese journal of clinical oncology, 2011, Volume: 41, Issue:6

    Topics: Adrenal Cortex Hormones; Adult; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents; Attitude

2011
In brief: fentanyl sublingual tablets (Abstral) for breathrough cancer pain.
    The Medical letter on drugs and therapeutics, 2011, May-16, Volume: 53, Issue:1364

    Topics: Administration, Sublingual; Fentanyl; Humans; Neoplasms; Pain; Tablets

2011
The ITFR, impulsive tail flick reflex by short duration nociceptive stimuli.
    Journal of neuroscience methods, 2011, Jul-15, Volume: 199, Issue:1

    Topics: Afferent Pathways; Animals; Electromyography; Electroshock; Fentanyl; Hot Temperature; Lasers; Male;

2011
Rapid hypnosis as an anaesthesia adjunct for evacuation of postpartum vulval haematoma.
    The Australian & New Zealand journal of obstetrics & gynaecology, 2011, Volume: 51, Issue:3

    Topics: Acetaminophen; Adult; Anesthetics, Intravenous; Blood Loss, Surgical; Female; Fentanyl; Hematoma; Hu

2011
Utilisation of transdermal fentanyl in Germany from 2004 to 2006.
    Pharmacoepidemiology and drug safety, 2012, Volume: 21, Issue:2

    Topics: Aged; Analgesics, Opioid; Databases, Factual; Dose-Response Relationship, Drug; Female; Fentanyl; Ge

2012
Enhanced analgesic responses after preferential delivery of morphine and fentanyl to the olfactory epithelium in rats.
    Anesthesia and analgesia, 2011, Volume: 113, Issue:3

    Topics: Administration, Intranasal; Analgesics, Opioid; Analysis of Variance; Animals; Central Nervous Syste

2011
Involvement of neuropeptide FF receptors in neuroadaptive responses to acute and chronic opiate treatments.
    British journal of pharmacology, 2012, Volume: 165, Issue:2

    Topics: Adamantane; Analgesics, Opioid; Animals; Behavior, Animal; Conditioning, Classical; Dipeptides; Drug

2012
Prospective, observational study of the depth of anesthesia during oocyte retrieval using a total intravenous anesthetic technique and the Bispectral index monitor.
    Fertility and sterility, 2011, Volume: 96, Issue:3

    Topics: Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Conscious Sedation; Female; Fentanyl; Huma

2011
Disaster after the plaster. Fentanyl withdrawal symptoms in a curable hospice patient.
    The European journal of general practice, 2011, Volume: 17, Issue:4

    Topics: Aged, 80 and over; Analgesics, Opioid; Colonic Neoplasms; Drug Administration Schedule; Female; Fent

2011
Inconsistencies in opioid equianalgesic ratios: clinical and research implications.
    Journal of pain & palliative care pharmacotherapy, 2008, Volume: 22, Issue:4

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Analgesics, Opioid; Delayed-Action Preparati

2008
Fentanyl nasal spray (Lazanda) for pain.
    The Medical letter on drugs and therapeutics, 2011, Dec-12, Volume: 53, Issue:1379-1380

    Topics: Administration, Intranasal; Analgesics, Opioid; Drug Approval; Drug Interactions; Drug Therapy, Comb

2011
The burden of endoscopic retrograde cholangiopancreatography (ERCP) performed with the patient under conscious sedation.
    Surgical endoscopy, 2012, Volume: 26, Issue:8

    Topics: Aged; Cholangiopancreatography, Endoscopic Retrograde; Conscious Sedation; Female; Fentanyl; Humans;

2012
Dissecting the relative contribution of central versus peripheral opioid analgesia: are the analgesic and adverse effects of opioids inseparable?
    European journal of pain (London, England), 2012, Volume: 16, Issue:5

    Topics: Analgesics, Opioid; Animals; Fentanyl; Loperamide; Male; Morphine; Pain; Receptors, Opioid; Spinal C

2012
Relative contributions of peripheral versus supraspinal or spinal opioid receptors to the antinociception of systemic opioids.
    European journal of pain (London, England), 2012, Volume: 16, Issue:5

    Topics: Analgesics, Opioid; Animals; Fentanyl; Inflammation; Loperamide; Male; Morphine; Pain; Rats; Rats, W

2012
Assessment of pain in sedated and mechanically ventilated patients: an observational study.
    Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Analysis of Variance; Behavior; Cons

2012
Pharmacokinetics of oxycodone after subcutaneous administration in a critically ill population compared with a healthy cohort.
    Anaesthesia and intensive care, 2012, Volume: 40, Issue:2

    Topics: Absorption; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Area Under Curve; Biolog

2012
Role of μ-opioid system in the formation of memory of placebo responses.
    Molecular psychiatry, 2013, Volume: 18, Issue:2

    Topics: Adult; Analgesics, Opioid; Brain; Female; Fentanyl; Humans; Male; Mental Recall; Neuropsychological

2013
Rocky.
    Palliative & supportive care, 2012, Volume: 10, Issue:2

    Topics: Analgesics, Opioid; Female; Fentanyl; Humans; Neoplasm Metastasis; Ovarian Neoplasms; Pain; Pain Man

2012
Safety of prehospital intravenous fentanyl for adult trauma patients.
    The journal of trauma and acute care surgery, 2012, Volume: 72, Issue:3

    Topics: Adult; Analgesics, Opioid; Dose-Response Relationship, Drug; Female; Fentanyl; Follow-Up Studies; Hu

2012
[Efficacy and safety of low-dose matrix-type transdermal fentanyl applied for opioid initiation].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:5

    Topics: Administration, Cutaneous; Aged; Analgesics, Opioid; Female; Fentanyl; Humans; Male; Neoplasms; Pain

2012
Striatal μ-opioid receptor availability predicts cold pressor pain threshold in healthy human subjects.
    Neuroscience letters, 2012, Jul-11, Volume: 521, Issue:1

    Topics: Adult; Carbon Radioisotopes; Cold Temperature; Corpus Striatum; Fentanyl; Humans; Male; Pain; Pain T

2012
[Peripheral acting mediators pain and analgesia potentiate the central analgesic action of fentanyl and dipyrone].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2012, Volume: 98, Issue:3

    Topics: Adenosine; Adenosine Triphosphate; Analgesia; Analgesics; Animals; Dipyrone; Dose-Response Relations

2012
A novel long-acting transdermal fentanyl solution for dogs. Editorial.
    Journal of veterinary pharmacology and therapeutics, 2012, Volume: 35 Suppl 2

    Topics: Administration, Cutaneous; Analgesics, Opioid; Animals; Delayed-Action Preparations; Dog Diseases; D

2012
Utilisation of transdermal fentanyl in Germany from 2004 to 2006.
    Pharmacoepidemiology and drug safety, 2012, Volume: 21, Issue:8

    Topics: Analgesics, Opioid; Female; Fentanyl; Humans; Male; Pain

2012
Population pharmacokinetics of transdermal fentanyl in patients with cancer-related pain.
    Journal of pain & palliative care pharmacotherapy, 2012, Volume: 26, Issue:2

    Topics: Administration, Cutaneous; Adult; Aged; Analgesics, Opioid; Cytochrome P-450 CYP3A; Dose-Response Re

2012
Fentanyl (transmucosal).
    Journal of pain and symptom management, 2012, Volume: 44, Issue:1

    Topics: Administration, Mucosal; Analgesics, Opioid; Fentanyl; Humans; Pain

2012
Utilisation of transdermal fentanyl in Germany from 2004-2006 by Edeltraut Garbe and colleagues.
    Pharmacoepidemiology and drug safety, 2012, Volume: 21, Issue:8

    Topics: Analgesics, Opioid; Female; Fentanyl; Humans; Male; Pain

2012
Lozenge risks.
    British dental journal, 2012, Volume: 213, Issue:5

    Topics: Chemistry, Pharmaceutical; Dental Caries; Dextrans; Female; Fentanyl; Humans; Liver Neoplasms; Narco

2012
Pain management.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23 Suppl 10

    Topics: Analgesics, Opioid; Dose-Response Relationship, Drug; Fentanyl; Humans; Neoplasms; Pain; Pain Manage

2012
Intranasal fentanyl in the palliative care of newborns and infants.
    Journal of pain and symptom management, 2013, Volume: 46, Issue:2

    Topics: Administration, Intranasal; Analgesics, Opioid; Female; Fentanyl; Humans; Infant, Newborn; Infant, P

2013
Involvement of spinal orexin A in the electroacupuncture analgesia in a rat model of post-laparotomy pain.
    BMC complementary and alternative medicine, 2012, Nov-22, Volume: 12

    Topics: Abdomen; Acupuncture Points; Analgesia; Animals; Electroacupuncture; Fentanyl; Hindlimb; Hyperalgesi

2012
Safety and efficacy of oral transmucosal fentanyl citrate for prehospital pain control on the battlefield.
    The journal of trauma and acute care surgery, 2012, Volume: 73, Issue:6 Suppl 5

    Topics: Administration, Mucosal; Administration, Oral; Afghanistan; Analgesics, Opioid; Analysis of Variance

2012
Analgesic effect of switching from oral opioids to a once-a-day fentanyl citrate transdermal patch in patients with lung cancer.
    The American journal of hospice & palliative care, 2013, Volume: 30, Issue:7

    Topics: Administration, Cutaneous; Analgesics, Opioid; Citric Acid; Fentanyl; Humans; Lung Neoplasms; Neopla

2013
[2 cases of successful symptom management at home by using opioid rotation from a fentanyl preparation to a continuous subcutaneous injection of morphine hydrochloride, at a dose less than the equivalent dose based on the conversion table].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39 Suppl 1

    Topics: Analgesics, Opioid; Female; Fentanyl; Home Care Services; Humans; Injections, Intravenous; Male; Mid

2012
Fentanyl pectin nasal spray: a novel intranasal delivery method for the treatment of breakthrough cancer pain.
    Expert review of clinical pharmacology, 2013, Volume: 6, Issue:1

    Topics: Administration, Intranasal; Analgesics, Opioid; Dose-Response Relationship, Drug; Drug Carriers; Fen

2013
Use of intravenous fentanyl against morphine tolerance in breakthrough cancer pain: a case series and literature review.
    The American journal of hospice & palliative care, 2014, Volume: 31, Issue:1

    Topics: Analgesics, Opioid; Drug Administration Routes; Drug Tolerance; Female; Fentanyl; Humans; Male; Midd

2014
Oral transmucosal fentanyl: new preparation. For breakthrough cancer pain when morphine fails.
    Prescrire international, 2002, Volume: 11, Issue:60

    Topics: Administration, Buccal; Administration, Oral; Adult; Analgesics, Opioid; Child; Dosage Forms; Fentan

2002
[Pain therapy. Exaggerated anxiety regarding opioid administration].
    MMW Fortschritte der Medizin, 2002, Jul-26, Volume: 144, Issue:29-30

    Topics: Administration, Cutaneous; Analgesics, Opioid; Anxiety; Chronic Disease; Fentanyl; Humans; Pain

2002
Fentanyl-associated syndrome of inappropriate antidiuretic hormone secretion.
    Pharmacotherapy, 2002, Volume: 22, Issue:9

    Topics: Administration, Cutaneous; Adult; Analgesics, Opioid; Fatal Outcome; Female; Fentanyl; Humans; Inapp

2002
Dextromethorphan and ketamine potentiate the antinociceptive effects of mu- but not delta- or kappa-opioid agonists in a mouse model of acute pain.
    Pharmacology, biochemistry, and behavior, 2002, Volume: 74, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics

2002
[Fentanyl by buccal administration. Fifty to hundred times stronger than morphine against pain].
    Revue de l'infirmiere, 2002, Issue:83

    Topics: Administration, Buccal; Analgesics, Opioid; Chemistry, Pharmaceutical; Drug Monitoring; Fentanyl; Hu

2002
Pain activation of human supraspinal opioid pathways as demonstrated by [11C]-carfentanil and positron emission tomography (PET).
    Pain, 2002, Volume: 99, Issue:3

    Topics: Adult; Area Under Curve; Brain; Capsaicin; Carbon Radioisotopes; Fentanyl; Humans; Male; Middle Aged

2002
Large-amplitude 5-HT1A receptor activation: a new mechanism of profound, central analgesia.
    Neuropharmacology, 2002, Volume: 43, Issue:6

    Topics: Acetates; Adrenergic Uptake Inhibitors; Amines; Aminopyridines; Analgesia; Analgesics; Animals; Cell

2002
Interactions of NMDA antagonists and an alpha 2 agonist with mu, delta and kappa opioids in an acute nociception assay.
    Acta anaesthesiologica Belgica, 2002, Volume: 53, Issue:3

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic

2002
The use of fentanyl and alfentanil sprays for episodic pain.
    Palliative medicine, 2002, Volume: 16, Issue:6

    Topics: Alfentanil; Analgesics, Opioid; Fentanyl; Humans; Pain; Palliative Care

2002
[Treatment of pain with opioid analgesics and the role of TTS-fentanyl (Durogesic)].
    Reumatizam, 2001, Volume: 48, Issue:2

    Topics: Administration, Cutaneous; Analgesics, Opioid; Chronic Disease; Fentanyl; Humans; Pain

2001
[Treatment of chronic pain--use of transdermal fentanyl (Durogesic TTS)].
    Reumatizam, 2002, Volume: 49, Issue:2

    Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Disease; Female; Fen

2002
Opioid rotation in the treatment of joint pain. A review of 67 cases.
    Joint bone spine, 2002, Volume: 69, Issue:5

    Topics: Administration, Cutaneous; Administration, Oral; Analgesics, Opioid; Buprenorphine; Drug Administrat

2002
Intranasal fentanyl reduces acute pain in children in the emergency department: a safety and efficacy study.
    Emergency medicine (Fremantle, W.A.), 2002, Volume: 14, Issue:3

    Topics: Administration, Intranasal; Analgesics; Child; Child, Preschool; Emergency Service, Hospital; Fentan

2002
Heat-associated increase in transdermal fentanyl absorption.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2003, Jan-15, Volume: 60, Issue:2

    Topics: Administration, Cutaneous; Adult; Aged; Analgesics, Opioid; Female; Fentanyl; Hot Temperature; Human

2003
Longitudinal follow-up of TTS-fentanyl use in patients with cancer-related pain: results of a compassionate-use study with special focus on elderly patients.
    Current medical research and opinion, 2002, Volume: 18, Issue:8

    Topics: Administration, Cutaneous; Aged; Analgesics, Opioid; Constipation; Female; Fentanyl; Follow-Up Studi

2002
Pain intensity after laseruvulopalatoplasty and tonsillectomy.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2003, Volume: 128, Issue:2

    Topics: Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Female; Fentanyl; Follow-Up Stud

2003
Large-dose intravenous methotrexate-induced cutaneous toxicity: can oral magnesium oxide reduce pain?
    Anesthesia and analgesia, 2003, Volume: 96, Issue:5

    Topics: Abdominal Neoplasms; Adolescent; Analgesics, Opioid; Antimetabolites, Antineoplastic; Burkitt Lympho

2003
Clinically important changes in acute pain outcome measures: a validation study.
    Journal of pain and symptom management, 2003, Volume: 25, Issue:5

    Topics: Acute Disease; Administration, Buccal; Analgesics, Opioid; Fentanyl; Humans; Neoplasms; Outcome Asse

2003
Clinically important changes in acute pain outcome measures: a validation study.
    Journal of pain and symptom management, 2003, Volume: 25, Issue:5

    Topics: Acute Disease; Administration, Buccal; Analgesics, Opioid; Fentanyl; Humans; Neoplasms; Outcome Asse

2003
Clinically important changes in acute pain outcome measures: a validation study.
    Journal of pain and symptom management, 2003, Volume: 25, Issue:5

    Topics: Acute Disease; Administration, Buccal; Analgesics, Opioid; Fentanyl; Humans; Neoplasms; Outcome Asse

2003
Clinically important changes in acute pain outcome measures: a validation study.
    Journal of pain and symptom management, 2003, Volume: 25, Issue:5

    Topics: Acute Disease; Administration, Buccal; Analgesics, Opioid; Fentanyl; Humans; Neoplasms; Outcome Asse

2003
Clinically important changes in acute pain outcome measures: a validation study.
    Journal of pain and symptom management, 2003, Volume: 25, Issue:5

    Topics: Acute Disease; Administration, Buccal; Analgesics, Opioid; Fentanyl; Humans; Neoplasms; Outcome Asse

2003
Clinically important changes in acute pain outcome measures: a validation study.
    Journal of pain and symptom management, 2003, Volume: 25, Issue:5

    Topics: Acute Disease; Administration, Buccal; Analgesics, Opioid; Fentanyl; Humans; Neoplasms; Outcome Asse

2003
Clinically important changes in acute pain outcome measures: a validation study.
    Journal of pain and symptom management, 2003, Volume: 25, Issue:5

    Topics: Acute Disease; Administration, Buccal; Analgesics, Opioid; Fentanyl; Humans; Neoplasms; Outcome Asse

2003
Clinically important changes in acute pain outcome measures: a validation study.
    Journal of pain and symptom management, 2003, Volume: 25, Issue:5

    Topics: Acute Disease; Administration, Buccal; Analgesics, Opioid; Fentanyl; Humans; Neoplasms; Outcome Asse

2003
Clinically important changes in acute pain outcome measures: a validation study.
    Journal of pain and symptom management, 2003, Volume: 25, Issue:5

    Topics: Acute Disease; Administration, Buccal; Analgesics, Opioid; Fentanyl; Humans; Neoplasms; Outcome Asse

2003
A safe and effective method for converting patients from transdermal to intravenous fentanyl for the treatment of acute cancer-related pain.
    Cancer, 2003, Jun-15, Volume: 97, Issue:12

    Topics: Administration, Cutaneous; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Female; F

2003
Re: The fentanyl transdermal patch in the dying phase.
    Journal of pain and symptom management, 2003, Volume: 26, Issue:1

    Topics: Administration, Cutaneous; Analgesics, Opioid; Fentanyl; Humans; Pain; Terminal Care

2003
The terminal cancer patient: effects of age, gender, and primary tumor site on opioid dose.
    Pain medicine (Malden, Mass.), 2003, Volume: 4, Issue:2

    Topics: Age Factors; Aged; Analgesics, Opioid; Dose-Response Relationship, Drug; Female; Fentanyl; Humans; M

2003
Pharmacokinetics of fentanyl following intravenous and transdermal administration in horses.
    Equine veterinary journal, 2003, Volume: 35, Issue:5

    Topics: Administration, Cutaneous; Analgesics, Opioid; Animals; Area Under Curve; Cross-Over Studies; Dose-R

2003
Epidural anaesthesia for pain relief in labour.
    European journal of anaesthesiology, 2003, Volume: 20, Issue:8

    Topics: Adult; Amides; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthetics, Local;

2003
Transdermal fentanyl: informed prescribing is essential.
    European journal of pain (London, England), 2003, Volume: 7, Issue:5

    Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Disease; Dose-Respon

2003
NEUROLEPT-ANALGESIA AS ADJUNCT TO LOCAL ANESTHESIA IN INTRAOCULAR SURGERY; A PRELIMINARY REPORT.
    American journal of ophthalmology, 1965, Volume: 59

    Topics: Adjuvants, Anesthesia; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anesthesia, Local; Antipyret

1965
Procedural pain in newborns at risk for neurologic impairment.
    Pain, 2003, Volume: 105, Issue:1-2

    Topics: Analgesics, Opioid; Cohort Studies; Diagnostic Tests, Routine; Drug Administration Schedule; Fentany

2003
Agitated terminal delirium and association with partial opioid substitution and hydration.
    Journal of palliative medicine, 2003, Volume: 6, Issue:4

    Topics: Analgesics, Opioid; Delirium; Drug Administration Schedule; Female; Fentanyl; Humans; Japan; Male; M

2003
Intravenous fentanyl for cancer pain: a "fast titration" protocol for the emergency room.
    Journal of pain and symptom management, 2003, Volume: 26, Issue:3

    Topics: Adult; Aged; Analgesics, Opioid; Emergency Medical Services; Fentanyl; Humans; Injections, Intraveno

2003
Initial dose cascade of TTS fentanyl with proper adjuvant medications in cancer pain.
    Journal of Korean medical science, 2003, Volume: 18, Issue:5

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Dose-Response Relatio

2003
A one year health economic model comparing transdermal fentanyl with sustained-release morphine in the treatment of chronic noncancer pain.
    Journal of pain & palliative care pharmacotherapy, 2003, Volume: 17, Issue:2

    Topics: Administration, Cutaneous; Analgesics, Opioid; Cost-Benefit Analysis; Delayed-Action Preparations; D

2003
[Usefulness of fentanyl patch in home palliative care].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30 Suppl 1

    Topics: Administration, Cutaneous; Adult; Aged; Analgesics, Opioid; Caregivers; Female; Fentanyl; Home Care

2003
Therapy switching in patients receiving long-acting opioids.
    The Annals of pharmacotherapy, 2004, Volume: 38, Issue:3

    Topics: Administration, Cutaneous; Aged; Analgesics, Opioid; Comorbidity; Delayed-Action Preparations; Femal

2004
[Use of opioids against severe cancer pain].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2004, Feb-05, Volume: 124, Issue:3

    Topics: Analgesics, Opioid; Fentanyl; Humans; Morphine; Neoplasms; Oxycodone; Pain; Palliative Care

2004
Incidence of constipation associated with long-acting opioid therapy: a comparative study.
    Southern medical journal, 2004, Volume: 97, Issue:2

    Topics: Aged; Analgesics, Opioid; California; Constipation; Female; Fentanyl; Humans; Incidence; Male; Middl

2004
The effects of transdermal fentanyl on driving, cognitive performance, and balance in patients with chronic nonmalignant pain conditions.
    Pain medicine (Malden, Mass.), 2004, Volume: 5, Issue:1

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Automobile Driving; Chronic Disease; Cognition;

2004
[Breakthrough pain--analysis and therapy. A pilot study of a new drug, transmucosal fentanyl (Actiq)].
    Lakartidningen, 2004, Feb-12, Volume: 101, Issue:7

    Topics: Administration, Oral; Adult; Aged; Analgesics, Opioid; Female; Fentanyl; Humans; Male; Middle Aged;

2004
Electroencephalographic bicoherence is sensitive to noxious stimuli during isoflurane or sevoflurane anesthesia.
    Anesthesiology, 2004, Volume: 100, Issue:4

    Topics: Adult; Aged; Anesthesia; Anesthetics, Inhalation; Electroencephalography; Female; Fentanyl; Humans;

2004
Evaluation of safety and efficacy of transdermal therapeutic system-fentanyl in adult patients with gynecological cancer-related pain.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2004, Volume: 87, Issue:3

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Chronic Disease; Drug Delivery Systems; Fema

2004
A study of transdermal fentanyl in cancer pain at Aichi-Cancer Center.
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2004, Volume: 124, Issue:5

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Cancer Care Facilities; Chronic Disease;

2004
Severe withdrawal from short-term transdermal fentanyl after naloxone for uremic pruritus.
    Journal of pain and symptom management, 2004, Volume: 27, Issue:5

    Topics: Administration, Cutaneous; Analgesics, Opioid; Drug Interactions; Drug Therapy, Combination; Fentany

2004
Antiallodynic effects of loperamide and fentanyl against topical capsaicin-induced allodynia in unanesthetized primates.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:1

    Topics: Administration, Topical; Analgesics; Animals; Capsaicin; Dopamine; Female; Fentanyl; Loperamide; Mac

2004
Oral transmucosal abuse of transdermal fentanyl.
    Journal of psychopharmacology (Oxford, England), 2004, Volume: 18, Issue:2

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Chronic Disease; Depressive Disorder; Drug A

2004
Emergency medicine research on the front lines.
    Annals of emergency medicine, 2004, Volume: 44, Issue:2

    Topics: Analgesics, Opioid; Biomedical Research; Emergency Medicine; Fentanyl; Humans; Military Personnel; P

2004
[Therapy of break-through pain].
    Krankenpflege Journal, 2004, Volume: 42, Issue:3-4

    Topics: Administration, Oral; Analgesics, Opioid; Biological Availability; Clinical Trials as Topic; Drug De

2004
Epidural analgesia for acute symphysis pubis dysfunction in the second trimester.
    International journal of obstetric anesthesia, 2004, Volume: 13, Issue:1

    Topics: Adult; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Female; Fentanyl; H

2004
Peripheral versus central antinociceptive actions of 6-amino acid-substituted derivatives of 14-O-methyloxymorphone in acute and inflammatory pain in the rat.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 312, Issue:2

    Topics: Acute Disease; Analgesics; Animals; Central Nervous System; Dose-Response Relationship, Drug; Fentan

2005
Utilisation pattern of fentanyl transdermal system in The Netherlands.
    Pharmacoepidemiology and drug safety, 2005, Volume: 14, Issue:2

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Analgesics, Opioid; Child; Child, Preschool; Coh

2005
Transdermal fentanyl: caution in the use of high doses.
    Palliative medicine, 2004, Volume: 18, Issue:7

    Topics: Administration, Cutaneous; Analgesics, Opioid; Fentanyl; Humans; Morphine; Pain; Palliative Care; Re

2004
Differences between primary somatosensory cortex- and vertex-derived somatosensory-evoked potentials in the rat.
    Brain research, 2004, Dec-31, Volume: 1030, Issue:2

    Topics: Anesthetics; Animals; Brain Mapping; Cerebral Cortex; Electric Stimulation; Evoked Potentials, Somat

2004
Patching up your pain. The transition from pill to patch has spawned products for both chronic and short-term ailments.
    Health news (Waltham, Mass.), 2004, Volume: 10, Issue:12

    Topics: Administration, Cutaneous; Analgesics; Fentanyl; Humans; Lidocaine; Nonprescription Drugs; Pain

2004
[Chronic pain--new patch size expands therapy spectrum].
    MMW Fortschritte der Medizin, 2004, Dec-02, Volume: 146, Issue:49

    Topics: Administration, Cutaneous; Analgesics, Opioid; Chronic Disease; Clinical Trials as Topic; Fentanyl;

2004
[Paradigm change in therapy of moderate chronic opioid responsive pain. Fentanyl alternative to weak opioids].
    MMW Fortschritte der Medizin, 2004, Dec-02, Volume: 146, Issue:49

    Topics: Administration, Cutaneous; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Chronic Dise

2004
Participation of ATP-sensitive K+ channels in the peripheral antinociceptive effect of fentanyl in rats.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2005, Volume: 38, Issue:1

    Topics: Analgesia; Analgesics, Opioid; Animals; Carrageenan; Dose-Response Relationship, Drug; Fentanyl; Mal

2005
Physicians' knowledge of transdermal fentanyl.
    Palliative medicine, 2005, Volume: 19, Issue:1

    Topics: Administration, Cutaneous; Adult; Analgesics, Opioid; Clinical Competence; Family Practice; Fentanyl

2005
A comparison of the resources used in advanced cancer care between two different strong opioids: an analysis of naturalistic practice in the UK.
    Current medical research and opinion, 2005, Volume: 21, Issue:2

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Analgesics, Opioid; Child; Child, Preschool; Del

2005
Equipotent doses of transdermal fentanyl and transdermal buprenorphine in patients with cancer and noncancer pain: results of a retrospective cohort study.
    Clinical therapeutics, 2005, Volume: 27, Issue:2

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Buprenorphine; Chroni

2005
Withdrawal symptom after discontinuation of transdermal fentanyl at a daily dose of 0.6 mg.
    Pharmacy world & science : PWS, 2005, Volume: 27, Issue:1

    Topics: Administration, Cutaneous; Adult; Aged; Analgesics, Opioid; Female; Fentanyl; Humans; Male; Middle A

2005
Principles of pain management: agents used for somatic pain.
    Connecticut medicine, 2005, Volume: 69, Issue:3

    Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Chronic

2005
[Clinical trials: early use of transdermal opioid therapy].
    MMW Fortschritte der Medizin, 2005, Apr-28, Volume: 147, Issue:17

    Topics: Administration, Cutaneous; Adult; Analgesics, Opioid; Antirheumatic Agents; Arthritis; Chronic Disea

2005
The impact of intrapartum analgesia on infant feeding.
    BJOG : an international journal of obstetrics and gynaecology, 2005, Volume: 112, Issue:7

    Topics: Analgesics, Opioid; Antiemetics; Bottle Feeding; Breast Feeding; Cohort Studies; Dose-Response Relat

2005
Simplifying prehospital analgesia. Why certain medications should or should not be used for pain management in the field.
    JEMS : a journal of emergency medical services, 2005, Volume: 30, Issue:7

    Topics: Analgesics; Anesthetics, Combined; Butorphanol; Emergency Medical Services; Emergency Medical Techni

2005
Fentanyl trauma analgesia use in air medical scene transports.
    The Journal of emergency medicine, 2005, Volume: 29, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Air Ambulances; Analgesia; Analgesics, Opioid; Child; Ch

2005
Does the use of fentanyl in epidural solutions for postthoracotomy pain management in neonates affect surgical outcome?
    Journal of pediatric surgery, 2005, Volume: 40, Issue:7

    Topics: Adjuvants, Anesthesia; Analgesics; Anesthesia, Epidural; Anesthetics, Local; Bupivacaine; Cystic Ade

2005
Mini-dose titration of the transdermal fentanyl patch--a novel approach by adjusting the area of absorption.
    Journal of pain and symptom management, 2005, Volume: 30, Issue:1

    Topics: Absorption; Administration, Cutaneous; Analgesics, Opioid; Delayed-Action Preparations; Fentanyl; Hu

2005
Diclofenac pretreatment for propofol.
    Anaesthesia and intensive care, 2005, Volume: 33, Issue:4

    Topics: Anesthetics, Intravenous; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Fentanyl; Humans; Mid

2005
Evaluation of pain-related behavior, bone destruction and effectiveness of fentanyl, sufentanil, and morphine in a murine model of cancer pain.
    Pharmacology, biochemistry, and behavior, 2005, Volume: 82, Issue:1

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Bone Neoplasms; Disease Models, Animal; Fentanyl; Mic

2005
Opioid switch in palliative care, opioid choice by clinical need and opioid availability.
    European journal of pain (London, England), 2005, Volume: 9, Issue:5

    Topics: Aged; Ambulatory Care Facilities; Analgesics, Opioid; Buprenorphine; Cohort Studies; Dose-Response R

2005
Inter- and intra-individual variability in transdermal fentanyl absorption in cancer pain patients.
    Oncology reports, 2005, Volume: 14, Issue:4

    Topics: Administration, Cutaneous; Aged; Analgesics, Opioid; Drug Delivery Systems; Female; Fentanyl; Humans

2005
Changes in the prescribed daily doses of transdermal fentanyl and transdermal buprenorphine during treatment of patients with cancer and noncancer pain in Germany: results of a retrospective cohort study.
    Clinical therapeutics, 2005, Volume: 27, Issue:7

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Buprenorphine; Cohort

2005
Hyperpharmacotherapy in someone you love.
    JAAPA : official journal of the American Academy of Physician Assistants, 2005, Volume: 18, Issue:9

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anecdotes as Topic; Dementia; Drug Monitoring; Female;

2005
Pain recurrence on the third day after application of a transdermal fentanyl patch.
    Pharmacy world & science : PWS, 2005, Volume: 27, Issue:4

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Female; Fentanyl; Hum

2005
Rectal insertion of fentanyl patches: a new route of toxicity.
    Annals of emergency medicine, 2005, Volume: 46, Issue:5

    Topics: Administration, Rectal; Adult; Analgesics, Opioid; Drug Overdose; Emergency Medicine; Fentanyl; Huma

2005
Rifampin reduces the analgesic effect of transdermal fentanyl.
    The Annals of pharmacotherapy, 2005, Volume: 39, Issue:12

    Topics: Adenocarcinoma; Administration, Cutaneous; Aged; Analgesics, Opioid; Antibiotics, Antitubercular; Dr

2005
Physicians' knowledge of transdermal fentanyl.
    Palliative medicine, 2005, Volume: 19, Issue:7

    Topics: Administration, Cutaneous; Analgesics, Opioid; Clinical Competence; Fentanyl; Health Knowledge, Atti

2005
Physicians' knowledge of transdermal fentanyl.
    Palliative medicine, 2005, Volume: 19, Issue:7

    Topics: Administration, Cutaneous; Analgesics, Opioid; Clinical Competence; Fentanyl; Health Knowledge, Atti

2005
Determining pain levels in patients treated with maggot debridement therapy.
    Journal of wound care, 2005, Volume: 14, Issue:10

    Topics: Acetaminophen; Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic;

2005
[Effective pain therapy with good tolerability. New opioid administration form by transdermal patch].
    MMW Fortschritte der Medizin, 2005, Nov-17, Volume: 147, Issue:46

    Topics: Administration, Cutaneous; Analgesics, Opioid; Chronic Disease; Clinical Trials as Topic; Fentanyl;

2005
Pain and anxiety: two problems, two solutions.
    Journal of vascular and interventional radiology : JVIR, 2005, Volume: 16, Issue:12

    Topics: Adaptation, Psychological; Analgesia, Patient-Controlled; Anesthetics, Intravenous; Anxiety; Attenti

2005
Effectiveness of transdermal fentanyl patch for treatment of acute pain due to oral mucositis in patients receiving stem cell transplantation.
    Transplantation proceedings, 2005, Volume: 37, Issue:10

    Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Female; Fentanyl; Humans; Leukemia; Lymphoma, Non-Hodgk

2005
[Reliably pain free with a new fentanyl patch].
    MMW Fortschritte der Medizin, 2005, Dec-15, Volume: 147, Issue:51-52

    Topics: Administration, Cutaneous; Analgesics, Opioid; Chronic Disease; Fentanyl; Humans; Pain

2005
[Simple to use--superior adhesiveness].
    MMW Fortschritte der Medizin, 2005, Dec-15, Volume: 147, Issue:51-52

    Topics: Adhesiveness; Administration, Cutaneous; Analgesics, Opioid; Chronic Disease; Fentanyl; Humans; Pain

2005
Is the use of transdermal fentanyl inappropriate according to the WHO guidelines and the EAPC recommendations? A study of cancer patients in Italy.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2006, Volume: 14, Issue:5

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Female; Fentanyl; Gui

2006
[Pain: etiology and drug treatment].
    Krankenpflege Journal, 2005, Volume: 43, Issue:7-10

    Topics: Acute Disease; Administration, Cutaneous; Analgesics, Opioid; Chronic Disease; Fentanyl; Humans; Noc

2005
Anesthetic management of a labouring parturient with urticaria pigmentosa.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2006, Volume: 53, Issue:4

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Intravenous;

2006
[Medico-legal aspects of the use of fentanyl patches].
    Der Anaesthesist, 2006, Volume: 55, Issue:6

    Topics: Administration, Cutaneous; Analgesics, Opioid; Chronic Disease; Drug Overdose; Fentanyl; Germany; Hu

2006
The antiallodynic effect of NMDA antagonists in neuropathic pain outlasts the duration of the in vivo NMDA antagonism.
    Neuropharmacology, 2006, Volume: 51, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics, Opioid; Animals; Cold Temperat

2006
LC-MS/MS analysis of fentanyl and norfentanyl in a fatality due to application of multiple Durogesic transdermal therapeutic systems.
    Forensic science international, 2007, Jul-04, Volume: 169, Issue:2-3

    Topics: Administration, Cutaneous; Aged; Analgesics, Opioid; Bile; Chromatography, Liquid; Female; Fentanyl;

2007
Can fentanyl be systemically absorbed when administered vaginally? A feasibility study.
    Journal of palliative care, 2006,Spring, Volume: 22, Issue:1

    Topics: Administration, Intravaginal; Adult; Alberta; Analgesics, Opioid; Chemistry, Pharmaceutical; Drug Ad

2006
[Sedation in children: how and for who?].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2006, Volume: 13, Issue:6

    Topics: Alfentanil; Anesthesia, General; Child; Conscious Sedation; Contraindications; Cooperative Behavior;

2006
Fentanyl patch sufficient analgesia for only one day.
    Journal of pain and symptom management, 2006, Volume: 31, Issue:5

    Topics: Administration, Cutaneous; Aged; Analgesics, Opioid; Bone Neoplasms; Fentanyl; Humans; Male; Pain; P

2006
Drug utilization review on a tertiary palliative care unit.
    Journal of pain and symptom management, 2006, Volume: 31, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anti-Anxiety Agents; Cost-Benefit Analysis; Drug

2006
Synergistic interaction between fentanyl and the histamine H3 receptor agonist R-(alpha)-methylhistamine, on the inhibition of nociception and plasma extravasation in mice.
    European journal of pharmacology, 2006, Jul-10, Volume: 541, Issue:1-2

    Topics: Animals; Dose-Response Relationship, Drug; Drug Synergism; Extravasation of Diagnostic and Therapeut

2006
Resolution of sweating after switching from transdermal fentanyl to oral morphine sulphate.
    Palliative medicine, 2006, Volume: 20, Issue:3

    Topics: Administration, Oral; Analgesics, Opioid; Female; Fentanyl; Humans; Hyperhidrosis; Liver Neoplasms;

2006
Vertex-recorded, rather than primary somatosensory cortex-recorded, somatosensory-evoked potentials signal unpleasantness of noxious stimuli in the rat.
    Brain research bulletin, 2006, Jul-31, Volume: 70, Issue:3

    Topics: Analgesics, Opioid; Animals; Conditioning, Classical; Dose-Response Relationship, Drug; Electroencep

2006
Skin reaction to both morphine and fentanyl attenuated by steroids and antihistaminics.
    Journal of pain and symptom management, 2006, Volume: 32, Issue:2

    Topics: Aged; Analgesics, Opioid; Drug Combinations; Female; Fentanyl; Histamine H1 Antagonists; Humans; Mor

2006
Patterns of dosage changes with transdermal buprenorphine and transdermal fentanyl for the treatment of noncancer and cancer pain: a retrospective data analysis in Germany.
    Clinical therapeutics, 2006, Volume: 28, Issue:8

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Buprenorphine; Dose-R

2006
Economic evaluation of Durogesic in moderate to severe, nonmalignant, chronic pain in Germany.
    The European journal of health economics : HEPAC : health economics in prevention and care, 2006, Volume: 7, Issue:4

    Topics: Administration, Cutaneous; Analgesics, Opioid; Buprenorphine; Chronic Disease; Cost-Benefit Analysis

2006
Profound pain due to propofol injection triggered severe bronchospasm in a smoker--A case report.
    Middle East journal of anaesthesiology, 2006, Volume: 18, Issue:5

    Topics: Albuterol; Aminophylline; Anesthetics, Inhalation; Anesthetics, Intravenous; Anti-Inflammatory Agent

2006
Three-cycle fentanyl patch system significantly improves pain control in gynecologic cancer.
    The journal of obstetrics and gynaecology research, 2006, Volume: 32, Issue:6

    Topics: Adenocarcinoma, Papillary; Administration, Cutaneous; Aged; Analgesics, Opioid; Female; Fentanyl; Ge

2006
Nerve growth factor governs the enhanced ability of opioids to suppress inflammatory pain.
    Brain : a journal of neurology, 2007, Volume: 130, Issue:Pt 2

    Topics: Analgesics, Opioid; Animals; Apoptosis Regulatory Proteins; Calcitonin Gene-Related Peptide; Enzyme-

2007
Safety and efficacy of fentanyl administered by patient controlled analgesia in children with cancer pain.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2007, Volume: 15, Issue:5

    Topics: Adolescent; Anesthetics, Intravenous; Child; Female; Fentanyl; Humans; Italy; Male; Neoplasms; Pain;

2007
Cephalon used improper tactics to sell drug, probe finds.
    Wall Street journal (Eastern ed.), 2006, Nov-21

    Topics: Analgesics, Opioid; Drug Industry; Drug Labeling; Fentanyl; Humans; Marketing; Neoplasms; Pain

2006
Sudden deflation of a tourniquet caused by lowering of the operating table.
    Annales francaises d'anesthesie et de reanimation, 2007, Volume: 26, Issue:2

    Topics: Blood Loss, Surgical; Equipment Design; Equipment Failure; Fentanyl; Hand; Humans; Intraoperative Co

2007
Painful pemphigus vulgaris.
    Anesthesia and analgesia, 2007, Volume: 104, Issue:1

    Topics: Administration, Cutaneous; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Fentanyl; Gabapen

2007
Equianalgesic dosing of opioids.
    Journal of pain & palliative care pharmacotherapy, 2006, Volume: 20, Issue:4

    Topics: Analgesics, Opioid; Dose-Response Relationship, Drug; Fentanyl; Humans; Hydromorphone; Methadone; Pa

2006
Differentiating hemodynamic responses in rat primary somatosensory cortex during non-noxious and noxious electrical stimulation by optical imaging.
    Brain research, 2007, Feb-16, Volume: 1133, Issue:1

    Topics: Afferent Pathways; Analgesics, Opioid; Animals; Cerebrovascular Circulation; Electric Stimulation; E

2007
Failure of pain control using transdermal fentanyl during rifampicin treatment.
    Journal of pain and symptom management, 2007, Volume: 33, Issue:1

    Topics: Administration, Cutaneous; Analgesics, Opioid; Antibiotics, Antitubercular; Drug Interactions; Fenta

2007
Differences in tolerance to anti-hyperalgesic effects between chronic treatment with morphine and fentanyl under a state of pain.
    Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 2006, Volume: 26, Issue:5-6

    Topics: Analgesics, Opioid; Animals; Fentanyl; Freund's Adjuvant; Male; Mice; Mice, Inbred C57BL; Mice, Inbr

2006
Opioid self-administration in the nerve-injured rat: relevance of antiallodynic effects to drug consumption and effects of intrathecal analgesics.
    Anesthesiology, 2007, Volume: 106, Issue:2

    Topics: Adenosine; Analgesics, Opioid; Animals; Clonidine; Dose-Response Relationship, Drug; Fentanyl; Heroi

2007
Comment on Koltzenburg et al.: Differential sensitivity of three experimental pain models in detecting the analgesic effects of transdermal fentanyl and buprenorphine. Pain 2006;126:165-74.
    Pain, 2007, Volume: 128, Issue:3

    Topics: Administration, Cutaneous; Adult; Analgesics, Opioid; Buprenorphine; Cold Temperature; Cross-Over St

2007
Weighing in on the off-label use of Actiq for noncancer-related pain: a recipe for success or a recipe for disaster?
    Pain medicine (Malden, Mass.), 2007, Volume: 8, Issue:2

    Topics: Abnormalities, Drug-Induced; Administration, Oral; Adult; Analgesics, Opioid; Female; Fentanyl; Huma

2007
Medicating "Margaret".
    The Journal of clinical ethics, 2006,Winter, Volume: 17, Issue:4

    Topics: Advance Directives; Alzheimer Disease; Analgesics, Opioid; Antipsychotic Agents; Electroconvulsive T

2006
[Transdermal fentanyl in treating severe painful mucositis caused by autologous hematopoietic stem cell transplantation].
    Ai zheng = Aizheng = Chinese journal of cancer, 2007, Volume: 26, Issue:4

    Topics: Administration, Cutaneous; Adolescent; Adult; Analgesics, Opioid; Antineoplastic Combined Chemothera

2007
Intranasal fentanyl for acute pain: techniques to enhance efficacy.
    Annals of emergency medicine, 2007, Volume: 49, Issue:5

    Topics: Acute Disease; Administration, Intranasal; Adult; Analgesics, Opioid; Biological Availability; Child

2007
Clinical experience with transdermal and orally administered opioids in palliative care patients--a retrospective study.
    Japanese journal of clinical oncology, 2007, Volume: 37, Issue:4

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics, Opioid;

2007
Placebo effects on human mu-opioid activity during pain.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Jun-26, Volume: 104, Issue:26

    Topics: Analgesics, Opioid; Brain Chemistry; Carbon Radioisotopes; Fentanyl; Hot Temperature; Humans; Pain;

2007
Intraoperative analgesia for day-care surgery: practice trends.
    JPMA. The Journal of the Pakistan Medical Association, 2007, Volume: 57, Issue:6

    Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anal

2007
Ultra-low dose combined spinal-epidural anaesthesia.
    International journal of obstetric anesthesia, 2007, Volume: 16, Issue:4

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Combined; Ane

2007
Treating cancer-related breakthrough pain: the oral transmucosal route.
    International journal of palliative nursing, 2007, Volume: 13, Issue:7

    Topics: Administration, Oral; Drug Administration Routes; Fentanyl; Humans; Mouth Mucosa; Neoplasms; Pain; P

2007
Fentanyl in the prehospital setting.
    The American journal of emergency medicine, 2007, Volume: 25, Issue:7

    Topics: Administration, Intranasal; Analgesics, Opioid; Emergency Medical Services; Fentanyl; Humans; Pain;

2007
Fentanyl buccal tablet (Fentora) for breakthrough pain.
    The Medical letter on drugs and therapeutics, 2007, Sep-24, Volume: 49, Issue:1270

    Topics: Administration, Buccal; Analgesics, Opioid; Drug Interactions; Fentanyl; Humans; Neoplasms; Pain; Pa

2007
Nitrous oxide (N2O) prevents latent pain sensitization and long-term anxiety-like behavior in pain and opioid-experienced rats.
    Neuropharmacology, 2007, Volume: 53, Issue:6

    Topics: Analgesics, Opioid; Animals; Anxiety; Atmosphere Exposure Chambers; Behavior, Animal; Disease Models

2007
[Comparison of clinical effectiveness of thoracic epidural and intravenous patient-controlled analgesia for the treatment of rib fractures pain in intensive care unit].
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2007, Volume: 13, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Anal

2007
Toward freedom from cancer pain in Japan.
    Journal of pain & palliative care pharmacotherapy, 2007, Volume: 21, Issue:3

    Topics: Analgesics, Opioid; Drug Utilization; Fentanyl; Humans; Japan; Morphine; Neoplasms; Pain; Practice G

2007
A fentanyl-based pain management protocol provides early analgesia for adult trauma patients.
    The Journal of trauma, 2007, Volume: 63, Issue:4

    Topics: Adult; Analgesia; Analgesics, Opioid; Clinical Protocols; Dose-Response Relationship, Drug; Female;

2007
Opioid use in palliative care of children and young people with cancer.
    The Journal of pediatrics, 2008, Volume: 152, Issue:1

    Topics: Administration, Oral; Administration, Rectal; Adolescent; Adult; Analgesics, Opioid; Child; Child, P

2008
Fentanyl-induced neurotoxicity and paradoxic pain.
    Journal of pain and symptom management, 2008, Volume: 35, Issue:3

    Topics: Aged; Analgesics, Opioid; Fatal Outcome; Female; Fentanyl; Humans; Hyperalgesia; Leiomyosarcoma; Neu

2008
Chronic morphine use does not induce peripheral tolerance in a rat model of inflammatory pain.
    The Journal of clinical investigation, 2008, Volume: 118, Issue:3

    Topics: Animals; beta-Endorphin; Cells, Cultured; Cyclophosphamide; Drug Tolerance; Fentanyl; Guanosine 5'-O

2008
Vertebral augmentation: toward a safe and pain-free method for back pain.
    Minerva anestesiologica, 2008, Volume: 74, Issue:3

    Topics: Anesthetics, Intravenous; Fentanyl; Fractures, Spontaneous; Humans; Pain; Propofol; Spinal Fractures

2008
Assisted sedation: a safe and easy method for pain-free percutaneous vertebroplasty.
    Minerva anestesiologica, 2008, Volume: 74, Issue:3

    Topics: Aged; Anesthetics, Intravenous; Conscious Sedation; Female; Fentanyl; Humans; Hypnotics and Sedative

2008
Is actiq use in noncancer-related pain really "a recipe for success"?
    Pain medicine (Malden, Mass.), 2008, Volume: 9, Issue:2

    Topics: Abnormalities, Drug-Induced; Adult; Analgesics, Opioid; Female; Fentanyl; Humans; Pain; Pregnancy; S

2008
Spontaneously breathing technique for opioid tolerance.
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:4

    Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Inhalation; Anti-Inflammatory

2008
Overriding the blockade of antinociceptive actions of opioids in rats treated with extended-release naltrexone.
    Pharmacology, biochemistry, and behavior, 2008, Volume: 89, Issue:4

    Topics: Alcoholism; Analgesics, Opioid; Animals; Delayed-Action Preparations; Drug Interactions; Fentanyl; H

2008
Influence of prescription benefits on reported pain in cancer patients.
    Pain medicine (Malden, Mass.), 2008, Volume: 9, Issue:8

    Topics: Adult; Aged; Analgesics, Opioid; Female; Fentanyl; Humans; Insurance Coverage; Male; Medicaid; Middl

2008
Suppression of noxious-induced c-fos expression in the rat lumbar spinal cord by isoflurane alone or combined with fentanyl.
    Anesthesia and analgesia, 2008, Volume: 106, Issue:4

    Topics: Analgesics; Anesthesia; Animals; Drug Therapy, Combination; Electric Stimulation; Fentanyl; Isoflura

2008
Not so fast: the reformulation of fentanyl and breakthrough chronic non-cancer pain.
    Pain, 2008, Volume: 136, Issue:3

    Topics: Analgesics, Opioid; Chronic Disease; Drug Approval; Fentanyl; Humans; Neoplasms; Opioid-Related Diso

2008
Inadequate provision of postintubation anxiolysis and analgesia in the ED.
    The American journal of emergency medicine, 2008, Volume: 26, Issue:4

    Topics: Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Anxiety; Cohort Studies; Emergency Service, Ho

2008
Oral transmucosal fentanyl citrate--OTFC (ACTIQ) #103.
    Journal of palliative medicine, 2008, Volume: 11, Issue:4

    Topics: Administration, Oral; Analgesics, Opioid; Fentanyl; Humans; Neoplasms; Pain

2008
Unusual presentations of scorpion envenomation.
    Human & experimental toxicology, 2008, Volume: 27, Issue:1

    Topics: Adult; Analgesics, Opioid; Animals; Antivenins; Blood Cell Count; Blood Chemical Analysis; Echocardi

2008
The effects of prior fentanyl administration and of pain on fentanyl analgesia: tolerance to and enhancement of narcotic analgesia.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 213, Issue:2

    Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Fentanyl; Male; Pain;

1980
Should regional anesthesia and pharmacological agents such as beta blockers and opiates be utilized in modulating pain response?
    The Journal of trauma, 1984, Volume: 24, Issue:9 Suppl

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alfentanil; Analgesia; Analgesics; Anesth

1984
Opiate receptor binding-effect relationship: sufentanil and etorphine produce analgesia at the mu-site with low fractional receptor occupancy.
    Brain research, 1984, Jan-23, Volume: 291, Issue:2

    Topics: Animals; Brain; Diprenorphine; Drug Interactions; Etorphine; Fentanyl; Morphinans; Naloxone; Pain; R

1984
[Bupivacaine-fentanyl combination in obstetric epidural anesthesia. Apropos of 203 cases].
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1984, Volume: 25, Issue:9

    Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Apgar Score; Bupivacaine; Female; Fentanyl; Humans; I

1984
Epidural fentanyl in the management of severe pain.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1984, Feb-11, Volume: 65, Issue:6

    Topics: Catheterization; Epidural Space; Female; Fentanyl; Humans; Middle Aged; Pain; Thorax

1984
Dose-response suppression of noxiously evoked activity of WDR neurons by spinally administered fentanyl.
    Anesthesiology, 1983, Volume: 58, Issue:6

    Topics: Action Potentials; Animals; Cats; Dose-Response Relationship, Drug; Evoked Potentials; Female; Fenta

1983
Aspirin in the prevention of painful intravenous injection of disoprofol (ICI35,868) and diazepam (Valium).
    Anaesthesia, 1982, Volume: 37, Issue:8

    Topics: Adolescent; Adult; Anesthesia, Intravenous; Anesthetics; Aspirin; Diazepam; Female; Fentanyl; Humans

1982
The antinociceptive effects of epidural opiates in the cat: studies of the pharmacology and the effects of lipophilicity in spinal analgesia.
    Pain, 1982, Volume: 12, Issue:4

    Topics: Animals; Cats; Dose-Response Relationship, Drug; Epidural Space; Female; Fentanyl; Lipids; Male; Mep

1982
Further evidence validating adjuvant arthritis as an experimental model of chronic pain in the rat.
    Life sciences, 1982, Jul-05, Volume: 31, Issue:1

    Topics: Animals; Arthritis; Arthritis, Experimental; Body Weight; Chronic Disease; Disease Models, Animal; D

1982
The effects of high-dose fentanyl on cerebral circulation and metabolism in rats.
    Anesthesiology, 1982, Volume: 57, Issue:5

    Topics: Animals; Brain; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Electroencephalograph

1982
[Measurement of endorphins in human cerebrospinal fluid. Comparative study of various groups of patients].
    Revista espanola de fisiologia, 1982, Volume: 38, Issue:3

    Topics: Adult; Aged; Anesthetics; Animals; Biological Assay; Chronic Disease; Droperidol; Endorphins; Female

1982
Fentanyl reduces the intensity of painful tooth pulp sensations: controlling for detection of active drugs.
    Anesthesia and analgesia, 1982, Volume: 61, Issue:9

    Topics: Adolescent; Adult; Dental Pulp; Diazepam; Double-Blind Method; Drug Evaluation; Electric Stimulation

1982
[Treatment of postoperative pain by peridural analgesia: haemodynamic study (author's transl)].
    Revista espanola de anestesiologia y reanimacion, 1981, Volume: 28, Issue:4

    Topics: Adult; Anesthesia, Epidural; Droperidol; Fentanyl; Hemodynamics; Humans; Male; Middle Aged; Pain; Po

1981
Anesthetic management of whole-body hyperthermia for the treatment of cancer.
    Anesthesiology, 1980, Volume: 52, Issue:5

    Topics: Adolescent; Adult; Aged; Anesthetics; Body Temperature; Body Temperature Regulation; Chemical and Dr

1980
Postoperative pain relief by demand analgesia.
    Acta anaesthesiologica Belgica, 1980, Volume: 31 Suppl

    Topics: Analgesics; Computers; Feedback; Fentanyl; Humans; Infusions, Parenteral; Pain; Patient Participatio

1980
Pain relief.
    Pediatrics, 1995, Volume: 95, Issue:3

    Topics: Administration, Buccal; Candy; Child; Fentanyl; Humans; Pain; Premedication

1995
A multifactorial analysis to explain inadequate surgical analgesia after extradural block.
    British journal of anaesthesia, 1995, Volume: 75, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, Epidural; Anesthetics,

1995
Day-to-day titration of transdermal fentanyl is unwise.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 1995, Volume: 3, Issue:3

    Topics: Administration, Cutaneous; Delayed-Action Preparations; Drug Monitoring; Drug Overdose; Fentanyl; Hu

1995
Comfortable labor with intrathecal narcotics.
    Military medicine, 1995, Volume: 160, Issue:5

    Topics: Adolescent; Adult; Analgesia, Obstetrical; Drug Therapy, Combination; Female; Fentanyl; Humans; Inje

1995
The consumption of fentanyl is increased in rats with nociceptive but not with neuropathic pain.
    Pain, 1995, Volume: 60, Issue:2

    Topics: Analysis of Variance; Animals; Arthritis, Infectious; Central Nervous System; Choice Behavior; Fenta

1995
Stimulus intensity and the comparative efficacy of mu- and kappa-opioid agonists on nociceptive spinal reflexes in the rat.
    Brain research, 1994, Nov-14, Volume: 663, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; E

1994
Transdermal fentanyl.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1994, Volume: 111, Issue:5

    Topics: Administration, Cutaneous; Chronic Disease; Fentanyl; Humans; Neoplasms; Pain

1994
Conscious sedation of children.
    Annals of emergency medicine, 1994, Volume: 24, Issue:6

    Topics: Anxiety; Child; Conscious Sedation; Emergencies; Fentanyl; Humans; Midazolam; Pain

1994
[Comparison of continuous extradural analgesia during labor using 0.25% bupivacaine or mixtures of 0.25% bupivacaine and fentanyl].
    Ginekologia polska, 1994, Volume: 65, Issue:7

    Topics: Adult; Analgesia, Obstetrical; Bupivacaine; Drug Therapy, Combination; Female; Fentanyl; Humans; Lab

1994
Increased intracranial pressure after fentanyl administration in a child with closed head trauma.
    Pediatric emergency care, 1994, Volume: 10, Issue:2

    Topics: Animals; Child; Craniocerebral Trauma; Fentanyl; Humans; Intracranial Pressure; Male; Pain; Wounds,

1994
Repeat epidural analgesia and unilateral block.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1994, Volume: 41, Issue:7

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Bupivacaine; Delivery, Obstetric; Female; Fentan

1994
Epidural analgesia in the management of severe vaso-occlusive sickle cell crisis.
    Pediatrics, 1994, Volume: 93, Issue:2

    Topics: Analgesia, Epidural; Anemia, Sickle Cell; Child; Emergencies; Female; Fentanyl; Humans; Lidocaine; M

1994
Drug-induced methemoglobinemia in a healthy 20-year-old soldier undergoing shoulder surgery.
    Nurse anesthesia, 1993, Volume: 4, Issue:4

    Topics: Adult; Arthroscopy; Fentanyl; Humans; Male; Methemoglobinemia; Methylene Blue; Midazolam; Pain; Prop

1993
Intravenous abuse of transdermal fentanyl therapy in a chronic pain patient.
    Anesthesiology, 1993, Volume: 79, Issue:5

    Topics: Administration, Cutaneous; Adult; Chronic Disease; Female; Fentanyl; Humans; Pain; Substance Abuse,

1993
Dosage of transdermal fentanyl.
    Clinical pharmacy, 1993, Volume: 12, Issue:10

    Topics: Administration, Cutaneous; Administration, Oral; Fentanyl; Humans; Morphine; Pain

1993
Evaluation of recalcitrant pain in HIV-infected hospitalized patients.
    Journal of acquired immune deficiency syndromes, 1994, Volume: 7, Issue:1

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Chronic Disease; Female; Fentanyl; HIV Infec

1994
Managing pain with transdermal fentanyl.
    Nursing, 1994, Volume: 24, Issue:1

    Topics: Administration, Cutaneous; Fentanyl; Humans; Neoplasms; Pain; Therapeutic Equivalency

1994
In vivo iontophoresis of fentanyl and sufentanil in rats: pharmacokinetics and acute antinociceptive effects.
    Anesthesia and analgesia, 1993, Volume: 77, Issue:1

    Topics: Administration, Cutaneous; Animals; Electric Stimulation; Fentanyl; Iontophoresis; Male; Pain; Rats;

1993
Pain corner. Duragesic.
    AARN news letter, 1993, Volume: 49, Issue:5

    Topics: Administration, Cutaneous; Fentanyl; Humans; Pain

1993
Fentanyl transdermal system overdose secondary to cutaneous hyperthermia.
    Anesthesia and analgesia, 1993, Volume: 77, Issue:2

    Topics: Administration, Cutaneous; Adult; Drug Overdose; Female; Fentanyl; Hot Temperature; Humans; Neoplasm

1993
High transdermal fentanyl requirements in a patient with chronic cancer pain.
    The Annals of pharmacotherapy, 1993, Volume: 27, Issue:5

    Topics: Administration, Cutaneous; Adult; Carcinoma, Squamous Cell; Chronic Disease; Female; Fentanyl; Human

1993
Transdermal fentanyl for cancer pain. Repeated dose pharmacokinetics.
    Anesthesiology, 1993, Volume: 78, Issue:1

    Topics: Administration, Cutaneous; Adult; Aged; Breast Neoplasms; Colonic Neoplasms; Female; Fentanyl; Human

1993
Use of transdermal fentanyl for cancer pain management.
    American family physician, 1993, Volume: 47, Issue:4

    Topics: Administration, Cutaneous; Fentanyl; Humans; Injections, Intravenous; Morphine; Neoplasms; Pain; The

1993
Criteria for use of patient-controlled analgesia in adults.
    Clinical pharmacy, 1993, Volume: 12, Issue:2

    Topics: Adult; Analgesia, Patient-Controlled; Fentanyl; Humans; Meperidine; Pain

1993
Peds pain protocols.
    The American journal of nursing, 1993, Volume: 93, Issue:2

    Topics: Child; Conscious Sedation; Drug Combinations; Fentanyl; Humans; Midazolam; Pain; Premedication

1993
Opioid-induced muscle activity: implications for managing chronic pain.
    The Annals of pharmacotherapy, 1995, Volume: 29, Issue:11

    Topics: Adenocarcinoma, Mucinous; Aged; Analgesics, Opioid; Chronic Disease; Fentanyl; Humans; Hyperkinesis;

1995
Drug-use evaluation of transdermal fentanyl.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1995, Nov-15, Volume: 52, Issue:22

    Topics: Administration, Cutaneous; Analgesics, Opioid; Chronic Disease; Drug Utilization Review; Fentanyl; H

1995
Methohexital infusion technique for conscious sedation.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1996, Volume: 54, Issue:5

    Topics: Adolescent; Adult; Anesthesia Recovery Period; Anesthetics, Intravenous; Conscious Sedation; Coopera

1996
Using high-dose fentanyl patches.
    The American journal of nursing, 1996, Volume: 96, Issue:7

    Topics: Administration, Cutaneous; Analgesics, Opioid; Chronic Disease; Fentanyl; Humans; Lung Neoplasms; Ma

1996
Regional anaesthesia for repeat Caesarean section in a patient with phantom limb pain.
    Anaesthesia, 1996, Volume: 51, Issue:1

    Topics: Adult; Analgesics, Opioid; Anesthesia, Conduction; Anesthesia, Epidural; Anesthesia, Obstetrical; An

1996
Remembrance of times past: the significance of c-fos in pain.
    British journal of anaesthesia, 1996, Volume: 76, Issue:1

    Topics: Analgesia; Analgesics; Anesthetics, Inhalation; Animals; Biomarkers; Fentanyl; Humans; Nervous Syste

1996
Nitrous oxide or halothane, or both, fail to suppress c-fos expression in rat spinal cord dorsal horn neurones after subcutaneous formalin.
    British journal of anaesthesia, 1996, Volume: 76, Issue:1

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Behavior, Animal; Cell Count; Fentanyl;

1996
The use of propofol for sedation in the emergency department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 1996, Volume: 3, Issue:3

    Topics: Adult; Aged; Analgesia; Anesthetics, Intravenous; Conscious Sedation; Emergency Service, Hospital; F

1996
Analgesia and oral opioid consumption: strengths and shortcomings of methods.
    Pain, 1996, Volume: 64, Issue:2

    Topics: Analgesics, Opioid; Animals; Fentanyl; Pain; Rats; Self Administration

1996
Effects of the structurally novel opioid 14 alpha, 14' beta-[dithiobis [(2-oxo-2,1-ethanediyl)imino]]bis(7,8-dihydromorphinone) on schedule-controlled behavior and thermal nociception in rhesus monkeys.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 278, Issue:3

    Topics: Analgesics; Animals; Azocines; Behavior, Animal; Benzeneacetamides; Female; Fentanyl; Hot Temperatur

1996
EMLA cream for renal extracorporeal shock wave lithotripsy in ambulatory patients.
    European journal of anaesthesiology, 1996, Volume: 13, Issue:4

    Topics: Ambulatory Care; Analgesia; Analgesics, Opioid; Anesthetics, Local; Drug Combinations; Female; Fenta

1996
Fentanyl remaining in a transdermal system following three days of continuous use.
    The Annals of pharmacotherapy, 1995, Volume: 29, Issue:10

    Topics: Administration, Cutaneous; Analgesics, Opioid; Chronic Disease; Fentanyl; Humans; Medical Waste Disp

1995
The need for analgesia in elective cholecystectomies influenced by the time of day the operation is performed.
    Acta anaesthesiologica Scandinavica, 1996, Volume: 40, Issue:8 Pt 1

    Topics: Aged; Analgesics, Opioid; Cholecystectomy; Circadian Rhythm; Elective Surgical Procedures; Female; F

1996
[Tumor pain. Fentanyl TTS: a transdermal system for tumor pain therapy].
    Deutsche medizinische Wochenschrift (1946), 1995, Oct-13, Volume: 120, Issue:41 Suppl

    Topics: Administration, Cutaneous; Analgesics, Opioid; Fentanyl; Humans; Neoplasms; Pain

1995
A timely change of fentanyl patch.
    Palliative medicine, 1996, Volume: 10, Issue:4

    Topics: Administration, Cutaneous; Fentanyl; Humans; Pain; Patient Compliance; Time Factors

1996
Fentanyl transdermal system. Pain management at home.
    Canadian family physician Medecin de famille canadien, 1997, Volume: 43

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Drug Costs; Female; F

1997
Reversal by kappa-agonists of peritoneal irritation-induced ileus and visceral pain in rats.
    Life sciences, 1997, Volume: 60, Issue:9

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetic Aci

1997
Acute neuropsychiatric findings in a patient receiving fentanyl for cancer pain.
    Pain, 1997, Volume: 69, Issue:1-2

    Topics: Adenocarcinoma; Akathisia, Drug-Induced; Analgesics, Opioid; Confusion; Fentanyl; Hallucinations; Hu

1997
Quicker dosage adjustment for transdermal fentanyl.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1997, Jan-01, Volume: 54, Issue:1

    Topics: Administration, Cutaneous; Analgesics, Opioid; Fentanyl; Humans; Infusions, Intravenous; Pain

1997
An assessment of the peripheral antinociceptive potential of remoxipride, clonidine and fentanyl in sheep using the forelimb tourniquet.
    Journal of veterinary pharmacology and therapeutics, 1997, Volume: 20, Issue:3

    Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Clonidine; Dopamine Antagonists; Drug Evalua

1997
Nurses' knowledge about equianalgesia and opioid dosing.
    Cancer nursing, 1997, Volume: 20, Issue:3

    Topics: Administration, Cutaneous; Analgesics, Opioid; Delayed-Action Preparations; Educational Measurement;

1997
[Opioid intoxication. Inappropriate administration of transdermal fentanyl].
    Der Anaesthesist, 1997, Volume: 46, Issue:5

    Topics: Administration, Cutaneous; Adult; Analgesics, Opioid; Fentanyl; Humans; Male; Pain; Peripheral Nervo

1997
[Conversion from peridural to transdermal opiate analgesia in abdominal tumor pain syndrome].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 1997, Volume: 32, Issue:5

    Topics: Adult; Analgesia, Epidural; Bupivacaine; Carcinoma, Signet Ring Cell; Colonic Neoplasms; Combined Mo

1997
Reduction by fentanyl of the Cp50 values of propofol and hemodynamic responses to various noxious stimuli.
    Anesthesiology, 1997, Volume: 87, Issue:2

    Topics: Adult; Blood Pressure; Consciousness; Dose-Response Relationship, Drug; Evaluation Studies as Topic;

1997
Preliminary clinical use of a patient-controlled intranasal analgesia (PCINA) device.
    Anaesthesia and intensive care, 1997, Volume: 25, Issue:4

    Topics: Acute Disease; Administration, Inhalation; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Contro

1997
Case history: a step up the analgesic ladder.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1997, Volume: 8 Suppl 3

    Topics: Analgesics, Opioid; Breast Neoplasms; Female; Fentanyl; Humans; Middle Aged; Morphine; Pain; Quality

1997
Transdermal fentanyl for chronic pain.
    The American journal of nursing, 1997, Volume: 97, Issue:11

    Topics: Administration, Cutaneous; Analgesics, Opioid; Chronic Disease; Fentanyl; Humans; Morphine; Neoplasm

1997
Balancing symptom management.
    Oncology nursing forum, 1997, Volume: 24, Issue:8

    Topics: Adenocarcinoma; Administration, Cutaneous; Analgesics, Opioid; Antineoplastic Agents; Combined Modal

1997
Breakthrough pain with the fentanyl patch.
    The American journal of nursing, 1997, Volume: 97, Issue:12

    Topics: Administration, Oral; Analgesics, Opioid; Chronic Disease; Fentanyl; Humans; Neoplasms; Pain; Salvag

1997
Cholecystokinin inhibits peripheral opioid analgesia in inflamed tissue.
    Neuroscience, 1998, Volume: 82, Issue:2

    Topics: Analgesics, Opioid; Animals; Cholecystokinin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Enzy

1998
The absence of 'cross-tolerance' when switching from oral morphine to transdermal fentanyl.
    Palliative medicine, 1997, Volume: 11, Issue:6

    Topics: Administration, Cutaneous; Analgesics, Opioid; Delayed-Action Preparations; Drug Tolerance; Fentanyl

1997
Continuous fentanyl infusion: use in severe cancer pain.
    The Annals of pharmacotherapy, 1998, Volume: 32, Issue:3

    Topics: Aged; Analgesics, Opioid; Anesthetics, Intravenous; Fatal Outcome; Female; Fentanyl; Humans; Infusio

1998
A survey of transdermal fentanyl use in a major cancer center.
    Journal of pain and symptom management, 1998, Volume: 15, Issue:4

    Topics: Administration, Cutaneous; Analgesics, Opioid; Fentanyl; Health Care Surveys; Humans; Neoplasms; Pai

1998
Anesthesia for cesarean section in a pituitary dwarf.
    Anesthesiology, 1998, Volume: 89, Issue:1

    Topics: Adult; Analgesics, Opioid; Cesarean Section; Dwarfism; Female; Fentanyl; Humans; Injections, Spinal;

1998
Factors influencing quality of life in cancer patients: the role of transdermal fentanyl in the management of pain.
    Seminars in oncology, 1998, Volume: 25, Issue:3 Suppl 7

    Topics: Administration, Cutaneous; Analgesics, Opioid; Chronic Disease; Fentanyl; Humans; Neoplasms; Pain; Q

1998
Pulmonary administration of aerosolised fentanyl: pharmacokinetic analysis of systemic delivery.
    British journal of clinical pharmacology, 1998, Volume: 46, Issue:1

    Topics: Administration, Inhalation; Adult; Aerosols; Analgesics, Opioid; Biological Availability; Female; Fe

1998
Chronic cancer pain.
    The American journal of nursing, 1998, Volume: 98, Issue:8

    Topics: Administration, Cutaneous; Adult; Analgesics, Opioid; Chronic Disease; Female; Fentanyl; Humans; Neo

1998
Anti-allodynic actions of intravenous opioids in the nerve injured rat: potential utility of heroin and dihydroetorphine against neuropathic pain.
    European journal of pharmacology, 1998, Sep-11, Volume: 357, Issue:1

    Topics: Analgesics, Opioid; Animals; Drug Evaluation; Etorphine; Fentanyl; Heroin; Infusions, Intravenous; L

1998
A research-based guideline for appropriate use of transdermal fentanyl to treat chronic pain.
    Oncology nursing forum, 1998, Volume: 25, Issue:9

    Topics: Administration, Cutaneous; Analgesics, Opioid; Chronic Disease; Drug Costs; Evidence-Based Medicine;

1998
Prehospital fentanyl analgesia in air-transported pediatric trauma patients.
    Pediatric emergency care, 1998, Volume: 14, Issue:5

    Topics: Adolescent; Air Ambulances; Analgesia; Analgesics, Opioid; Boston; Child; Child, Preschool; Clinical

1998
Heat-related toxicity with the fentanyl transdermal patch.
    Journal of pain and symptom management, 1998, Volume: 16, Issue:5

    Topics: Administration, Cutaneous; Adult; Analgesics, Opioid; Fentanyl; HIV Infections; Hot Temperature; Hum

1998
Controlling bone pain. How to keep nausea and oversedation out of the picture.
    Nursing, 1998, Volume: 28, Issue:11

    Topics: Administration, Cutaneous; Aged; Analgesics, Opioid; Female; Fentanyl; Humans; Pain

1998
The NSAID dexketoprofen trometamol is as potent as mu-opioids in the depression of wind-up and spinal cord nociceptive reflexes in normal rats.
    Brain research, 1999, Jan-23, Volume: 816, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood-Brain Barrier; Depression, Chemical; Electri

1999
Intact proprioception and control of labour pain during epidural analgesia.
    Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:1

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthetics, Local; Bupivaca

1999
Opioid substitution to reduce adverse effects in cancer pain management.
    The Medical journal of Australia, 1999, Jan-18, Volume: 170, Issue:2

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Female; Fentanyl; Hospice Care; Humans; Male; Medical A

1999
Effect of fentanyl and naloxone on a thalamic induced painful response in intractable epileptic patients.
    Stereotactic and functional neurosurgery, 1998, Volume: 71, Issue:2

    Topics: Adult; Analgesics, Opioid; Electric Stimulation Therapy; Electrocardiography; Electroencephalography

1998
[Prolonged antinociceptive effect of poly (DL-lactic acid)-fentanyl composites after their intrathecal injection in rats].
    Masui. The Japanese journal of anesthesiology, 1999, Volume: 48, Issue:2

    Topics: Analgesics, Opioid; Animals; Delayed-Action Preparations; Drug Carriers; Fentanyl; Injections, Spina

1999
Calming fears, easing pain. Children's anesthesia tricky.
    FDA consumer, 1994, Volume: 28, Issue:8

    Topics: Anesthesia; Child; Child, Hospitalized; Child, Preschool; Clinical Trials as Topic; Drug Approval; F

1994
The use of transcutaneous electrical nerve stimulation during the biliary lithotripsy procedure.
    The Journal of stone disease, 1992, Volume: 4, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Intravenous; Cholelithiasis; Conscious Sedation; Female;

1992
Evaluation of intraarticular opioid analgesia for the relief of articular pain in the domestic fowl.
    Pharmacology, biochemistry, and behavior, 1999, Volume: 63, Issue:2

    Topics: Analgesia; Analgesics; Animals; Arthritis, Gouty; Buprenorphine; Chickens; Disease Models, Animal; F

1999
Epidural analgesia for labor pain is not associated with a decreased frequency of uterine activity.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 1999, Volume: 65, Issue:2

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthetics, Local; Bupivaca

1999
An effective way to manage breakthrough pain.
    RN, 1999, Volume: 62, Issue:5

    Topics: Analgesics, Opioid; Drug Therapy, Combination; Fentanyl; Humans; Male; Middle Aged; Morphine; Pain;

1999
[Value of transdermal fentanyl administration in child in palliative care].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 1999, Volume: 6, Issue:7

    Topics: Administration, Cutaneous; Analgesics, Opioid; Brain Neoplasms; Child; Fentanyl; Humans; Male; Neopl

1999
[Transdermal Phentanyl. New therapeutic option in chronic non-tumor-induced pain].
    Der Orthopade, 1999, Volume: 28, Issue:9 Suppl

    Topics: Analgesics, Opioid; Chronic Disease; Drug Therapy, Combination; Fentanyl; Humans; Morphine; Pain

1999
Local administration of mu or kappa opioid agonists attenuates capsaicin-induced thermal hyperalgesia via peripheral opioid receptors in rats.
    Psychopharmacology, 2000, Volume: 148, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics

2000
SYM-2081 a kainate receptor antagonist reduces allodynia and hyperalgesia in a freeze injury model of neuropathic pain.
    Brain research, 2000, Mar-06, Volume: 858, Issue:1

    Topics: Animals; Axons; Behavior, Animal; Cell Count; Fentanyl; Frostbite; Glutamates; Hindlimb; Hyperalgesi

2000
Nebulized and intranasal fentanyl in the management of cancer-related breakthrough pain.
    Palliative medicine, 2000, Volume: 14, Issue:1

    Topics: Administration, Inhalation; Administration, Intranasal; Aged; Aged, 80 and over; Analgesics, Opioid;

2000
Trends in medical use and abuse of opioid analgesics.
    JAMA, 2000, Apr-05, Volume: 283, Issue:13

    Topics: Analgesics, Opioid; Drug Utilization; Fentanyl; Humans; Hydromorphone; Meperidine; Morphine; Opioid-

2000
Interference of pain control employing opioids in in vivo immunological experiments.
    Laboratory animals, 1999, Volume: 33, Issue:4

    Topics: Analgesics, Opioid; Animals; Buprenorphine; Disease Models, Animal; Dose-Response Relationship, Drug

1999
Pharmacologic reversal of pertussis toxin-induced thermal allodynia in mice.
    Neuropharmacology, 2000, Jul-24, Volume: 39, Issue:10

    Topics: Animals; Carbamazepine; Clonidine; Desipramine; Dizocilpine Maleate; Dose-Response Relationship, Dru

2000
Applications of intrathecal catheters in children.
    Paediatric anaesthesia, 2000, Volume: 10, Issue:4

    Topics: Adenocarcinoma; Adolescent; Analgesia, Epidural; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics

2000
Selective agonist of group II glutamate metabotropic receptors, LY354740, inhibits tolerance to analgesic effects of morphine in mice.
    British journal of pharmacology, 2000, Volume: 130, Issue:6

    Topics: Analgesics, Opioid; Animals; Bridged Bicyclo Compounds; Dose-Response Relationship, Drug; Drug Toler

2000
Transdermal fentanyl: new preparation. An alternative to morphine.
    Prescrire international, 1998, Volume: 7, Issue:37

    Topics: Analgesics, Opioid; Chronic Disease; Clinical Trials as Topic; Fentanyl; Humans; Morphine; Neoplasms

1998
[Conference: opioids in the treatment of chronic pain: moving into the future with Durogestic, Valencia, November 19-20, 1999].
    Polskie Archiwum Medycyny Wewnetrznej, 1999, Volume: 102, Issue:4

    Topics: Analgesics, Opioid; Chronic Disease; Fentanyl; Humans; Pain

1999
Drugs for pain.
    The Medical letter on drugs and therapeutics, 2000, Aug-21, Volume: 42, Issue:1085

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal

2000
[Oral transmucosal fentanyl citrate (OTFC) in the treatment of breakthrough pain].
    Ugeskrift for laeger, 2000, Sep-25, Volume: 162, Issue:39

    Topics: Administration, Oral; Analgesics, Opioid; Fentanyl; Humans; Mouth Mucosa; Neoplasms; Pain; Tablets

2000
Inadvertent administration of sufentanil instead of fentanyl during sedation/analgesia in a community hospital emergency department: a report of two cases.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2000, Volume: 7, Issue:11

    Topics: Accidents, Traffic; Anesthetics, Intravenous; Causality; Emergency Service, Hospital; Fentanyl; Foll

2000
A pitfall to avoid when starting a patient on transdermal fentanyl.
    Australian family physician, 2000, Volume: 29, Issue:12

    Topics: Administration, Cutaneous; Analgesics, Opioid; Female; Fentanyl; Humans; Middle Aged; Ovarian Neopla

2000
Transdermal fentanyl for chronic pain in AIDS: a pilot study.
    Journal of pain and symptom management, 2001, Volume: 21, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Administration, Cutaneous; Adult; Analgesics, Opioid; Chronic Di

2001
Economic evaluation of the fentanyl transdermal system for the treatment of chronic moderate to severe pain.
    Journal of pain and symptom management, 2001, Volume: 21, Issue:2

    Topics: Administration, Cutaneous; Analgesics, Opioid; Chronic Disease; Fentanyl; Health Care Costs; Humans;

2001
Morphine and alternative opioids in cancer pain: the EAPC recommendations.
    British journal of cancer, 2001, Mar-02, Volume: 84, Issue:5

    Topics: Administration, Oral; Analgesics, Opioid; Chemistry, Pharmaceutical; Drug Administration Schedule; F

2001
Opiate self-administration as a measure of chronic nociceptive pain in arthritic rats.
    Pain, 2001, Volume: 91, Issue:1-2

    Topics: Analgesics, Opioid; Animals; Arthritis; Behavior, Animal; Chronic Disease; Fentanyl; Male; Naloxone;

2001
The reversal of fentanyl-induced tolerance by administration of "small-dose" ketamine.
    Anesthesia and analgesia, 2001, Volume: 93, Issue:1

    Topics: Adult; Analgesics, Opioid; Anesthetics, Dissociative; Drug Therapy, Combination; Drug Tolerance; Fem

2001
Oral transmucosal fentanyl and sufentanil for incident pain.
    Journal of pain and symptom management, 2001, Volume: 22, Issue:2

    Topics: Administration, Sublingual; Adult; Analgesics, Opioid; Female; Fentanyl; Humans; Middle Aged; Neopla

2001
Re: Economic evaluation of the fentanyl transdermal system.
    Journal of pain and symptom management, 2001, Volume: 22, Issue:1

    Topics: Administration, Cutaneous; Analgesics, Opioid; Chronic Disease; Cost-Benefit Analysis; Fentanyl; Hum

2001
Re: Economic evaluation of fentanyl.
    Journal of pain and symptom management, 2001, Volume: 22, Issue:1

    Topics: Administration, Cutaneous; Analgesics, Opioid; Chronic Disease; Cost-Benefit Analysis; Fentanyl; Hum

2001
Transdermal fentanyl for pain relief in a paediatric palliative care population.
    Palliative medicine, 2001, Volume: 15, Issue:5

    Topics: Administration, Cutaneous; Adolescent; Analgesics, Opioid; Child; Child, Preschool; Female; Fentanyl

2001
Fetuses, fentanyl, and the stress response: signals from the beginnings of pain?
    Anesthesiology, 2001, Volume: 95, Issue:4

    Topics: Adult; Analgesics, Opioid; Female; Fentanyl; Fetal Diseases; Fetus; Hemodynamics; Hormones; Humans;

2001
Analgesic activity and opioid receptor selectivity of stereoisomers of ohmefentanyl isothiocyanate.
    European journal of pharmacology, 2001, Jul-27, Volume: 424, Issue:3

    Topics: Analgesics, Opioid; Animals; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Female;

2001
Do patients prefer transdermal fentanyl or sustained-release oral morphine for treatment of chronic non-cancer pain?
    The Journal of family practice, 2001, Volume: 50, Issue:10

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics, Opioid;

2001
[Real day in neonatology: JALON 2001, Nancy, October 6 2001. Fentanyl-ORL 1 receptor interactions in the perinatal period: should the "principle of precaution" be applied to premature newborns?].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2001, Volume: 8, Issue:10

    Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Fentanyl; Humans; Infant, Newborn; Infant, Newb

2001
Opioid therapy for chronic painful conditions.
    Medicine and health, Rhode Island, 2001, Volume: 84, Issue:10

    Topics: Analgesics, Opioid; Chronic Disease; Clinical Trials as Topic; Fentanyl; Humans; Karnofsky Performan

2001
Transmucosal fentanyl in ovarian cancer.
    Journal of pain and symptom management, 2002, Volume: 23, Issue:1

    Topics: Administration, Buccal; Adult; Aged; Analgesics, Opioid; Female; Fentanyl; Humans; Middle Aged; Ovar

2002
Opioid use in chronic pain management in the Philippines.
    European journal of pain (London, England), 2001, Volume: 5 Suppl A

    Topics: Analgesics, Opioid; Chronic Disease; Fentanyl; Health Knowledge, Attitudes, Practice; Humans; Meperi

2001
Long-acting fentanyl analogues: synthesis and pharmacology of N-(1-phenylpyrazolyl)-N-(1-phenylalkyl-4-piperidyl)propanamides.
    Bioorganic & medicinal chemistry, 2002, Volume: 10, Issue:3

    Topics: Amides; Analgesics, Opioid; Animals; Binding, Competitive; Brain; Fentanyl; Guinea Pigs; Humans; Mal

2002
[New Level III opioids of the World Health Organization].
    La Revue de medecine interne, 2002, Volume: 23, Issue:1

    Topics: Administration, Oral; Analgesics, Opioid; Clinical Trials as Topic; Delayed-Action Preparations; Fen

2002
All I have left. A daughter's dilemma.
    The American journal of nursing, 2002, Volume: 102, Issue:4

    Topics: Administration, Cutaneous; Analgesics, Opioid; Ethics, Nursing; Father-Child Relations; Fentanyl; Hu

2002
Intravenous fentanyl. Out of the operating room and gaining in popularity.
    The American journal of nursing, 2002, Volume: 102, Issue:4

    Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Fentanyl; Humans; Infusions, Intravenous; Pain

2002
Relative reinforcing effects of three opioids with different durations of action.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 301, Issue:2

    Topics: Alfentanil; Analgesics, Opioid; Animals; Female; Fentanyl; Injections, Intravenous; Macaca mulatta;

2002
[Opioid rotation in pain therapy. Case report].
    Der Anaesthesist, 2002, Volume: 51, Issue:1

    Topics: Administration, Cutaneous; Chronic Disease; Fentanyl; Humans; Hydromorphone; Injections, Subcutaneou

2002
[Impact of the commercialisation of transdermic fentanyl on the home care of terminal cancer patients].
    Atencion primaria, 2002, Mar-31, Volume: 29, Issue:5

    Topics: Administration, Cutaneous; Analgesics, Opioid; Commerce; Fentanyl; Home Care Services; Humans; Neopl

2002
[Paliative treatment: Treatment of chronic cancer pain (ii): the use of opiates].
    Atencion primaria, 2002, May-15, Volume: 29, Issue:8

    Topics: Administration, Cutaneous; Administration, Oral; Age Factors; Aged; Aged, 80 and over; Analgesics, O

2002
Transdermal fentanyl for the management of cancer pain: a survey of 1005 patients.
    Palliative medicine, 2001, Volume: 15, Issue:4

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Drug Administration S

2001
Potentiation by ketamine of fentanyl antinociception. I. An experimental study in rats showing that ketamine administered by non-spinal routes targets spinal cord antinociceptive systems.
    British journal of anaesthesia, 2002, Volume: 88, Issue:5

    Topics: Analgesics; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Synergism; Electric

2002
[Staged pain therapy plan. Opioid patch for chronic pain].
    MMW Fortschritte der Medizin, 2002, May-06, Volume: Suppl 2

    Topics: Administration, Cutaneous; Analgesics, Opioid; Chronic Disease; Dose-Response Relationship, Drug; Fe

2002
Excruciating perineal pain after intravenous dexamethasone.
    Anaesthesia and intensive care, 2002, Volume: 30, Issue:3

    Topics: Adult; Dexamethasone; Female; Fentanyl; Follow-Up Studies; Humans; Injections, Intravenous; Male; Pa

2002
Nociceptive stimulation prevents development of tolerance to narcotic analgesia.
    European journal of pharmacology, 1978, Jun-01, Volume: 49, Issue:3

    Topics: Analgesics, Opioid; Animals; Drug Tolerance; Fentanyl; Pain; Physical Stimulation; Rats; Reaction Ti

1978
Conscious sedation with intravenous drugs: a study of amnesia.
    Journal of oral surgery (American Dental Association : 1965), 1978, Volume: 36, Issue:3

    Topics: Adult; Amnesia; Anesthesia, Dental; Anesthesia, Intravenous; Anxiety; Diazepam; Drug Combinations; F

1978
[Use of phentanyl with droperidol or seduxen in nitrous oxide anesthesia in patients with blood vessel diseases of the lower extremities accompanied by pain syndrome].
    Klinicheskaia khirurgiia, 1979, Issue:2

    Topics: Adult; Anesthesia, Inhalation; Diazepam; Droperidol; Fentanyl; Humans; Middle Aged; Nitrous Oxide; P

1979
[Characteristics of combined nitrous oxide nacrosis and premedication with phentanyl and droperidol or phentanyl and seduxen in patients with pain syndrome caused by blood vessel diseases of the lower extremities].
    Vestnik khirurgii imeni I. I. Grekova, 1979, Volume: 122, Issue:2

    Topics: Adult; Aged; Anesthesia, Endotracheal; Diazepam; Droperidol; Drug Therapy, Combination; Fentanyl; Hu

1979
Objective tests of analgesic drugs in ponies.
    American journal of veterinary research, 1979, Volume: 40, Issue:8

    Topics: Analgesics; Animals; Disease Models, Animal; Female; Fentanyl; Horse Diseases; Horses; Male; Meperid

1979
The effects of intravenous fentanyl, morphine and naloxone on nociceptive responses of neurones in the rat caudal medulla.
    Neuropharmacology, 1978, Volume: 17, Issue:7

    Topics: Animals; Electric Stimulation; Electroencephalography; Fentanyl; Male; Medulla Oblongata; Morphine;

1978
[Evaluation of the possibilities and adequacy of central analgesia as a component of general anesthesia].
    Vestnik Akademii meditsinskikh nauk SSSR, 1975, Issue:2

    Topics: Analgesia; Anesthesia, General; Fentanyl; Heart Defects, Congenital; Humans; Pain

1975
Patient-controlled analgesia with fentanyl in children.
    Clinical pediatrics, 1992, Volume: 31, Issue:3

    Topics: Abdominal Pain; Analgesia, Patient-Controlled; Bone Marrow Transplantation; Child; Child, Preschool;

1992
Pharmacological profile of a potent, efficacious fentanyl derivative in rhesus monkeys.
    Psychopharmacology, 1992, Volume: 109, Issue:3

    Topics: Animals; Discrimination, Psychological; Dose-Response Relationship, Drug; Female; Fentanyl; Macaca m

1992
Can midazolam diminish sufentanil analgesia in patients with major trauma? A retrospective study with 43 patients.
    Drug metabolism and drug interactions, 1992, Volume: 10, Issue:1-2

    Topics: Adult; Analgesics; Fentanyl; Humans; Midazolam; Pain; Retrospective Studies; Sufentanil; Wounds and

1992
Possible treatment for meralgia paresthetica after coronary bypass operations.
    The Journal of thoracic and cardiovascular surgery, 1992, Volume: 104, Issue:5

    Topics: Coronary Artery Bypass; Fentanyl; Humans; Methylprednisolone; Pain; Paresthesia; Postoperative Compl

1992
[Changes in the pain produced by the peripheral venous injection of propofol when it is combined with lidocaine or fentanyl].
    Revista medica de Panama, 1992, Volume: 17, Issue:3

    Topics: Adolescent; Adult; Aged; Child; Female; Fentanyl; Humans; Injections, Intravenous; Lidocaine; Male;

1992
Transdermal fentanyl and initial dose-finding with patient-controlled analgesia in cancer pain. A pilot study with 20 terminally ill cancer patients.
    Pain, 1992, Volume: 50, Issue:3

    Topics: Administration, Cutaneous; Adult; Aged; Analgesia; Dose-Response Relationship, Drug; Female; Fentany

1992
[Intrathecal morphine therapy in children with cancer].
    Cahiers d'anesthesiologie, 1992, Volume: 40, Issue:7

    Topics: Bupivacaine; Child; Child, Preschool; Female; Fentanyl; Humans; Infant; Injections, Spinal; Male; Mo

1992
[The antinociceptive effects of fentanyl, midazolam and clonidine and their interactions in the spinal dorsal horn].
    Masui. The Japanese journal of anesthesiology, 1992, Volume: 41, Issue:12

    Topics: Animals; Cats; Clonidine; Drug Combinations; Drug Synergism; Fentanyl; Injections, Spinal; Male; Mid

1992
The role of the fentanyl series for pain management: novel delivery systems.
    Journal of pain and symptom management, 1992, Volume: 7, Issue:3 Suppl

    Topics: Administration, Cutaneous; Drug Delivery Systems; Fentanyl; Humans; Pain

1992
Diffuse rash associated with transdermal fentanyl.
    Clinical pharmacy, 1992, Volume: 11, Issue:3

    Topics: Administration, Cutaneous; Carcinoma; Drug Eruptions; Female; Fentanyl; Humans; Lung Neoplasms; Midd

1992
Midazolam-fentanyl sedation in conjunction with local anesthesia during oocyte retrieval for in vitro fertilization.
    Journal of assisted reproduction and genetics, 1992, Volume: 9, Issue:1

    Topics: Drug Therapy, Combination; Female; Fentanyl; Fertilization in Vitro; Humans; Injections, Intramuscul

1992
Value of transdermal fentanyl.
    Clinical pharmacy, 1992, Volume: 11, Issue:7

    Topics: Administration, Cutaneous; Fentanyl; Humans; Pain

1992
Effects of perineural opioids on nerve conduction of N. suralis in man.
    Acta neurologica Scandinavica, 1992, Volume: 85, Issue:5

    Topics: Adult; Anesthesia, Epidural; Anesthesiology; Endorphins; Female; Fentanyl; Humans; Injections, Epidu

1992
Reversal by naloxone of spinal antinociceptive effects of fentanyl, ketocyclazocine and midazolam.
    European journal of anaesthesiology, 1991, Volume: 8, Issue:5

    Topics: Analgesia, Epidural; Animals; Catheters, Indwelling; Dose-Response Relationship, Drug; Drug Toleranc

1991
Spinally mediated antinociception following intrathecal chlordiazepoxide--further evidence for a benzodiazepine spinal analgesic effect.
    European journal of anaesthesiology, 1991, Volume: 8, Issue:5

    Topics: Analgesia, Epidural; Animals; Catheters, Indwelling; Chlordiazepoxide; Dose-Response Relationship, D

1991
Bilateral and differential changes in spinal mu, delta and kappa opioid binding in rats with a painful, unilateral neuropathy.
    Pain, 1991, Volume: 46, Issue:3

    Topics: Analgesics; Animals; Autoradiography; Behavior, Animal; Benzeneacetamides; Enkephalin, D-Penicillami

1991
The effects of sham and full spinalization on the systemic potency of mu- and kappa-opioids on spinal nociceptive reflexes in rats.
    British journal of pharmacology, 1991, Volume: 104, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics

1991
New heteroaryl derivatives of fentanyl.
    The Journal of pharmacy and pharmacology, 1991, Volume: 43, Issue:1

    Topics: Analgesics; Animals; Chemical Phenomena; Chemistry; Fentanyl; Pain; Rats; Structure-Activity Relatio

1991
Analgesia versus sedation during Broviac catheter placement.
    American journal of perinatology, 1991, Volume: 8, Issue:4

    Topics: Blood Glucose; Blood Pressure; Catheterization; Epinephrine; Female; Fentanyl; Heart Rate; Humans; I

1991
Protection by U-50,488H against beta-chlornaltrexamine antagonism of nitrous oxide antinociception in mice.
    Brain research, 1991, May-17, Volume: 549, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia;

1991
Tonic pain perception in the mouse: differential modulation by three receptor-selective opioid agonists.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics

1991
Oral transmucosal fentanyl citrate for analgesia and sedation in the emergency department.
    Annals of emergency medicine, 1991, Volume: 20, Issue:10

    Topics: Administration, Oral; Adolescent; Adult; Child; Drug Evaluation; Emergencies; Female; Fentanyl; Huma

1991
Antinociceptive interaction between opioids and medetomidine: systemic additivity and spinal synergy.
    Anesthesiology, 1990, Volume: 73, Issue:6

    Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Drug Interactions; Drug Synergism; Fentanyl;

1990
Profiles of opioid analgesia in humans after intravenous bolus administration: alfentanil, fentanyl and morphine compared on experimental pain.
    Pain, 1990, Volume: 43, Issue:1

    Topics: Adult; Alfentanil; Analgesics, Opioid; Chemical Phenomena; Chemistry, Physical; Dental Pulp; Electri

1990
Epidural sufentanil for cancer pain.
    The American journal of nursing, 1990, Volume: 90, Issue:5

    Topics: Aged; Analgesia, Epidural; Analgesics; Carcinoma; Fentanyl; Humans; Infusion Pumps; Male; Pain; Rect

1990
On the mechanism by which midazolam causes spinally mediated analgesia.
    Anesthesiology, 1990, Volume: 73, Issue:2

    Topics: Analgesia, Epidural; Animals; Bicuculline; Cyclazocine; Dose-Response Relationship, Drug; Electric S

1990
Morphine and fentanyl anesthetic interactions with diazepam: relative antagonism in rats.
    Anesthesia and analgesia, 1990, Volume: 71, Issue:3

    Topics: Animals; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Fentanyl; Male; Morphine; Mo

1990
From the Food and Drug Administration.
    JAMA, 1990, Oct-10, Volume: 264, Issue:14

    Topics: Chronic Disease; Diet Fads; Dietary Fiber; Drug Combinations; Esophageal Stenosis; Fatty Alcohols; F

1990
[The value of epidural analgesia in acute pancreatitis].
    Schweizerische medizinische Wochenschrift, 1990, Feb-03, Volume: 120, Issue:5

    Topics: Analgesia, Epidural; Bupivacaine; Cardiovascular Diseases; Drug Therapy, Combination; Fentanyl; Huma

1990
Reduction of pain on injection caused by propofol.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1990, Volume: 37, Issue:2

    Topics: Adult; Alfentanil; Anesthesia, Intravenous; Double-Blind Method; Female; Fentanyl; Humans; Male; Pai

1990
Critique of the Dornier HM3 lithotripter as a clinical algesimeter.
    Pain, 1990, Volume: 40, Issue:3

    Topics: Analgesia, Epidural; Bupivacaine; Female; Fentanyl; Humans; Lithotripsy; Male; Pain; Pain Measuremen

1990
Modulation of pain-related somatosensory evoked potentials by general anesthesia.
    Anesthesia and analgesia, 1990, Volume: 71, Issue:3

    Topics: Adult; Anesthesia, General; Electroencephalography; Evoked Potentials, Auditory; Evoked Potentials,

1990
[Study on the analgesic effect of acupuncture with opioid receptors agonist in induced arthritic rats].
    Zhen ci yan jiu = Acupuncture research, 1989, Volume: 14, Issue:3

    Topics: Acupuncture Analgesia; Acupuncture Therapy; Animals; Arthritis; Arthritis, Experimental; Droperidol;

1989
Diagnostic epidural opioid technique.
    The Clinical journal of pain, 1989, Volume: 5, Issue:3

    Topics: Adult; Age Factors; Aged; Analgesia, Epidural; Chronic Disease; Disability Evaluation; Female; Fenta

1989
Potency of infused spinal antinociceptive agents is inversely related to magnitude of tolerance after continuous infusion.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:1

    Topics: Analgesics; Animals; Clonidine; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leu

1989
Spinal antinociceptive actions of mu- and kappa-opioids: the importance of stimulus intensity in determining 'selectivity' between reflexes to different modalities of noxious stimulus.
    British journal of pharmacology, 1989, Volume: 98, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics

1989
TTS-fentanyl.
    Cancer investigation, 1989, Volume: 7, Issue:5

    Topics: Administration, Cutaneous; Fentanyl; Humans; Neoplasms; Pain

1989
Poststenotic ischaemic myocardial dysfunction induced by peripheral nociceptive stimulation.
    European heart journal, 1989, Volume: 10 Suppl F

    Topics: Animals; Coronary Disease; Dogs; Electric Stimulation; Female; Fentanyl; Heart; Hemodynamics; Male;

1989
Epidural fentanyl and perineal pain in labour.
    Anaesthesia, 1989, Volume: 44, Issue:4

    Topics: Analgesia, Epidural; Anesthesia, Epidural; Anesthesia, Obstetrical; Bupivacaine; Female; Fentanyl; H

1989
Anaesthetic technique and pain in the newborn.
    Intensive care medicine, 1989, Volume: 15 Suppl 1

    Topics: Anesthesia; Fentanyl; Humans; Immune Tolerance; Infant, Newborn; Isoflurane; Pain

1989
[Intrathecal clonidine--how does it work in spinal fentanyl analgesia in rats?].
    Masui. The Japanese journal of anesthesiology, 1989, Volume: 38, Issue:4

    Topics: Adaptation, Physiological; Analgesia, Epidural; Animals; Clonidine; Drug Synergism; Female; Fentanyl

1989
Transdermal fentanyl for pain control in patients with cancer.
    Pain, 1989, Volume: 37, Issue:1

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Chronic Disease; Female; Fentanyl; Humans; Male;

1989
Long-term blockade of mu-opioid receptors suggests a role in control of ingestive behaviour, body weight and core temperature in the rat.
    Brain research, 1988, May-31, Volume: 450, Issue:1-2

    Topics: Animals; Benzomorphans; Body Temperature Regulation; Body Weight; Circadian Rhythm; Drinking Behavio

1988
[Influence of analgesics and acupuncture on cAMP content in the plasma of induced arthritic rats].
    Zhen ci yan jiu = Acupuncture research, 1988, Volume: 13, Issue:4

    Topics: Acupuncture Therapy; Animals; Arthritis; Arthritis, Experimental; Cyclic AMP; Droperidol; Electric S

1988
Electrophysiologic evidence for involvement of the pituitary region in opiate analgesia.
    Anesthesia and analgesia, 1985, Volume: 64, Issue:8

    Topics: Analgesics, Opioid; Animals; Dental Pulp; Electroencephalography; Evoked Potentials; Fentanyl; Male;

1985
[Use of morphine derivatives by the systemic route in the treatment of acute pain].
    Annales francaises d'anesthesie et de reanimation, 1985, Volume: 4, Issue:5

    Topics: Acute Disease; Alfentanil; Analgesics, Opioid; Buprenorphine; Fentanyl; Humans; Infusions, Parentera

1985
Alfentanil's analgesic, respiratory, and cardiovascular actions in relation to dose and plasma concentration in unanesthetized dogs.
    Anesthesiology, 1986, Volume: 64, Issue:3

    Topics: Alfentanil; Analgesics, Opioid; Animals; Awareness; Blood Pressure; Chromatography, Gas; Dogs; Dose-

1986
Enhancement by pain and stress of analgesia produced by epidural sufentanil in the rat.
    Anesthesiology, 1988, Volume: 69, Issue:1

    Topics: Analgesics, Opioid; Animals; Fentanyl; Injections, Epidural; Male; Pain; Rats; Rats, Inbred Strains;

1988
Intrathecal fentanyl depresses nociceptive flexion reflexes in patients with chronic pain.
    Anesthesiology, 1989, Volume: 70, Issue:2

    Topics: Aged; Chronic Disease; Depression, Chemical; Fentanyl; Humans; Injections, Spinal; Middle Aged; Noci

1989
A simultaneous comparison of fentanyl's analgesic effects on experimental and clinical pain.
    Pain, 1986, Volume: 24, Issue:2

    Topics: Affect; Back Pain; Fentanyl; Hot Temperature; Humans; Pain; Perception; Sensation

1986
Spinal sufentanil effects on spinal pain-transmission neurons in cats.
    Anesthesiology, 1986, Volume: 64, Issue:2

    Topics: Animals; Cats; Drug Interactions; Female; Fentanyl; Male; Naloxone; Neurons; Pain; Spinal Cord; Sufe

1986
Reversal by beta-funaltrexamine of the antinociceptive effect of opioid agonists in the rat.
    British journal of pharmacology, 1986, Volume: 88, Issue:4

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; B

1986
A dose-ratio comparison of mu and kappa agonists in formalin and thermal pain.
    Life sciences, 1986, Nov-24, Volume: 39, Issue:21

    Topics: Analgesia; Animals; Benzomorphans; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazoci

1986
A comparison of the effects of alfentanil applied to the spinal cord and intravenous alfentanil on noxiously evoked activity of dorsal horn neurons in the cat spinal cord.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:2

    Topics: Alfentanil; Analgesics; Animals; Cats; Evoked Potentials; Female; Fentanyl; Injections, Intravenous;

1986
Dose effects of alfentanil in human analgesia.
    Clinical pharmacology and therapeutics, 1986, Volume: 40, Issue:2

    Topics: Adult; Alfentanil; Analgesia; Dose-Response Relationship, Drug; Evoked Potentials; Fentanyl; Half-Li

1986
Failure of thyrotropin releasing hormone to reverse fentanyl-flunitrazepam anesthesia in man.
    Acta anaesthesiologica Belgica, 1986, Volume: 37, Issue:3

    Topics: Adult; Anesthesia; Arousal; Carbon Dioxide; Female; Fentanyl; Flunitrazepam; Humans; Male; Middle Ag

1986
Diagnostic epidural opioid blockade and chronic pain: preliminary report.
    Pain, 1985, Volume: 21, Issue:2

    Topics: Adult; Aged; Anesthesia, Epidural; Back Pain; Chronic Disease; Diagnosis, Differential; Female; Fent

1985
Objective assessment of opioid action by facial muscle surface electromyography (SEMG).
    Progress in neuro-psychopharmacology & biological psychiatry, 1988, Volume: 12, Issue:5

    Topics: Adult; Aged; Butorphanol; Electromyography; Evoked Potentials; Facial Muscles; Fentanyl; Humans; Mid

1988
[Potentiation concept in pharmacology].
    Minerva anestesiologica, 1988, Volume: 54, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Baclofen; Clomipramine; Diazepam; Drug Synergism; Drug Therapy, Combin

1988
Peripheral effect of fentanyl upon nociception in inflamed tissue of the rat.
    Neuroscience letters, 1988, Jan-22, Volume: 84, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Fentanyl; Hindlimb; Inflammation; Male; Nociceptors; Pain

1988
Effects of intrathecal fentanyl and lidocaine on somatosensory-evoked potentials, the H-reflex, and clinical responses.
    Anesthesia and analgesia, 1988, Volume: 67, Issue:6

    Topics: Electric Stimulation; Evoked Potentials, Somatosensory; Fentanyl; H-Reflex; Humans; Injections, Spin

1988
Ventilatory effects of continuous epidural infusion of fentanyl.
    Anesthesia and analgesia, 1988, Volume: 67, Issue:10

    Topics: Adult; Anesthesia, Epidural; Female; Fentanyl; Humans; Knee; Male; Pain; Time Factors; Ventilation-P

1988
The effects of pentobarbital, fentanyl-droperidol, ketamine-xylazine and ketamine-diazepam on noxious stimulus perception in adult male rats.
    Laboratory animal science, 1987, Volume: 37, Issue:6

    Topics: Anesthesia; Anesthetics; Animals; Diazepam; Droperidol; Drug Combinations; Fentanyl; Ketamine; Male;

1987
Modification of the analgesic effect and the effect on body temperature of morphine and fentanyl, included in liposomal suspensions.
    Acta physiologica et pharmacologica Bulgarica, 1986, Volume: 12, Issue:4

    Topics: Analgesics; Animals; Body Temperature; Fentanyl; Hexobarbital; Injections, Intraperitoneal; Liposome

1986
Use of fentanyl for sedation of mechanically ventilated neonates.
    Neonatal network : NN, 1987, Volume: 6, Issue:2

    Topics: Fentanyl; Humans; Infant, Newborn; Pain; Respiration, Artificial

1987
Peripheral effects of opioid drugs on capsaicin-sensitive neurones of the guinea-pig bronchus and rabbit ear.
    Naunyn-Schmiedeberg's archives of pharmacology, 1987, Volume: 336, Issue:3

    Topics: Acetylcholine; Animals; Atropine; Blood Pressure; Bronchi; Capsaicin; Ear, External; Enkephalin, Met

1987
New developments in opioid drug research for alleviation of animal pain.
    Journal of the American Veterinary Medical Association, 1987, Nov-15, Volume: 191, Issue:10

    Topics: Analgesia; Anesthesia; Animals; Fentanyl; Immobilization; Pain; Research; Species Specificity

1987
[Effects of lidocaine, meperidine or fentanyl on pain and clinical thrombophlebitis induced by intravenous diazepam].
    Ma zui xue za zhi = Anaesthesiologica Sinica, 1987, Volume: 25, Issue:3

    Topics: Adult; Diazepam; Female; Fentanyl; Humans; Hydrogen-Ion Concentration; Injections, Intravenous; Lido

1987
Phantom limb pain and epidural anesthesia for cesarean section.
    Anesthesiology, 1986, Volume: 65, Issue:2

    Topics: Adult; Analgesia; Anesthesia, Epidural; Cesarean Section; Fentanyl; Humans; Opium; Pain; Phantom Lim

1986
Surgical analgesia for cesarean delivery with epidural bupivacaine and fentanyl.
    Anesthesiology, 1986, Volume: 65, Issue:3

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Apgar Score; Bupivacaine; Cesarean Section; Do

1986
Failure of epidural anesthesia to prevent postoperative paralytic ileus.
    Anesthesiology, 1986, Volume: 65, Issue:3

    Topics: Anesthesia, Epidural; Anesthesia, General; Blood Glucose; Cholecystectomy; Colon; Fentanyl; Gastroin

1986
Morphine and fentanyl interactions with thiopental in relation to movement response to noxious stimulation.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:11

    Topics: Animals; Dose-Response Relationship, Drug; Drug Interactions; Fentanyl; Male; Morphine; Movement; Pa

1986
Fentanyl and alfentanil suppress brainstem pain transmission.
    Anesthesia and analgesia, 1985, Volume: 64, Issue:6

    Topics: Alfentanil; Animals; Brain Stem; Cats; Electric Stimulation; Evoked Potentials; Female; Fentanyl; In

1985
[The influence of a lesion of the bilateral N. accumbens upon the effects of electroacupuncture on the NRM neurons].
    Zhen ci yan jiu = Acupuncture research, 1985, Volume: 10, Issue:3

    Topics: Acupuncture Therapy; Animals; Caudate Nucleus; Electric Stimulation; Endorphins; Evoked Potentials;

1985
A method for studying cutaneous pain perception and analgesia in horses.
    Journal of pharmacological methods, 1985, Volume: 13, Issue:3

    Topics: Analgesia; Animals; Conditioning, Operant; Female; Fentanyl; Horses; Hot Temperature; Male; Narcotic

1985
Fentanyl "anesthesia" in dogs.
    Anesthesiology, 1985, Volume: 62, Issue:6

    Topics: Anesthesia, Intravenous; Animals; Dogs; Fentanyl; Pain

1985
Laparoscopic tubal clip sterilization under local anesthesia.
    Fertility and sterility, 1974, Volume: 25, Issue:9

    Topics: Adult; Anesthesia, Local; Diazepam; Drug Evaluation; Fallopian Tubes; Female; Fentanyl; Humans; Lapa

1974
[Value of neuroleptoanalgesia II in the treatment of pain during myocardial infarct].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1974, Oct-15, Volume: 27, Issue:20

    Topics: Acute Disease; Adult; Aged; Droperidol; Female; Fentanyl; Humans; Male; Middle Aged; Myocardial Infa

1974
[Comparative study of analgesic drugs in postoperative pain].
    Khirurgiia, 1972, Volume: 25, Issue:5

    Topics: Aminopyrine; Analgesics; Fentanyl; Humans; Meperidine; Pain; Pentazocine; Postoperative Complication

1972
Patient's views on general anaesthesia.
    Annales chirurgiae et gynaecologiae Fenniae, 1973, Volume: 62, Issue:5

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthesia, Inhalation; Attitude; Cognition; Diazepam;

1973
[Clinical evaluation of dehydrobenzperidol and fentanyl].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1972, Aug-21, Volume: 27, Issue:34

    Topics: Adult; Aged; Benperidol; Evaluation Studies as Topic; Female; Fentanyl; Humans; Injections, Intramus

1972
The relationship of the anesthetic agent to postoperative analgesic requirements.
    Southern medical journal, 1969, Volume: 62, Issue:10

    Topics: Aged; Anesthesia; Aortic Aneurysm; Cyclopropanes; Ethyl Ethers; Female; Fentanyl; Halothane; Humans;

1969
Neuroleptanalgesia II in recent myocardial infarction.
    Polish medical journal, 1969, Volume: 8, Issue:6

    Topics: Adult; Aged; Anxiety; Butyrophenones; Female; Fentanyl; Humans; Injections, Intravenous; Male; Middl

1969
A comparison of neuroleptanesthesia and halothane in neurosurgery.
    Archivum chirurgicum Neerlandicum, 1970, Volume: 22, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthesia, Inhalation; Blood Pressure; Child; Consciousness; Female; Fenta

1970
[Possibility of achieving a pain-free post-operative period following NLA II (Neuroleptoanalgesia II0].
    Der Anaesthesist, 1970, Volume: 19, Issue:7

    Topics: Adolescent; Adult; Analgesia; Benperidol; Child; Fentanyl; Humans; Methods; Middle Aged; Neuroleptan

1970
On the central sites for the antinociceptive action of morphine and fentanyl.
    Neuropharmacology, 1970, Volume: 9, Issue:6

    Topics: Animals; Behavior, Animal; Binding Sites; Carbon Isotopes; Cerebral Ventricles; Dental Pulp; Diencep

1970
EEG frequency content related to regional blood flow of cerebral cortex in cat.
    Experimental brain research, 1968, Volume: 5, Issue:1

    Topics: Animals; Cats; Cerebral Cortex; Cerebrovascular Circulation; Electroencephalography; Fentanyl; Krypt

1968
[Sensitivity to pain and pharmacological action. (Clinical and experimental studies of some pharmacological substances of common clinical use on sensitivity to pain stimuli)].
    Acta anaesthesiologica, 1968, Volume: 19

    Topics: Animals; Benperidol; Fentanyl; Haloperidol; Neuroleptanalgesia; Pain; Rats; Sensation

1968
[Sensitivity to pain and pharmacological action. (Clinical and experimental studies of some pharmacological substances of common clinical use of sensitivity to pain stimuli)].
    Acta anaesthesiologica, 1968, Volume: 19

    Topics: Animals; Benperidol; Fentanyl; Haloperidol; Neuroleptanalgesia; Pain; Rats; Sensation

1968
Some recent advances in analgesia.
    Virginia medical monthly, 1969, Volume: 96, Issue:1

    Topics: Analgesics; Anesthesia, General; Benperidol; Fentanyl; Humans; Methotrimeprazine; Pain; Pentazocine

1969
[Effects of phentanyl on spontaneous EEG activity, on behavioral and EEG reactivity to pain, on primary cortical potentials evoked by means of peripheral trigeminal electric stimulations in the rabbit].
    Minerva anestesiologica, 1965, Volume: 31, Issue:8

    Topics: Animals; Electroencephalography; Fentanyl; Pain; Rabbits

1965
[Extra-operative anesthesiological importance of the drugs used in neuroleptoanalgesia].
    Acta anaesthesiologica, 1965, Volume: 16

    Topics: Anesthesia; Anesthesia, Obstetrical; Benperidol; Fentanyl; Fever; Humans; Movement Disorders; Neurol

1965