Page last updated: 2024-10-27

fentanyl and Cough

fentanyl has been researched along with Cough in 96 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.

Research Excerpts

ExcerptRelevanceReference
"To assess the effects of intravenous (IV) fentanyl on cough reflex and quality of endotracheal intubation (ETI) in cats."9.69Effect of intravenous fentanyl on cough reflex and quality of endotracheal intubation in cats. ( Martín Bellido, V; Martínez I Ferré, B; McDonald, H; Vettorato, E, 2023)
"The study aimed to determine the efficacy of lidocaine at different low doses to reduce fentanyl-induced cough (FIC)."9.51Low-dose lidocaine attenuates fentanyl-induced cough: A double-blind randomized controlled trial. ( Jinawong, S; Munjupong, S; Phuvachoterojanaphokin, N; Watanaboonyongcharoen, G, 2022)
"Intravenous bolus injection of fentanyl has been frequently reported to be associated with cough reflex during patient anesthesia."9.41Comparison of lidocaine, huffing maneuver and combination of both in prevention fentanyl induced cough before induction of anesthesia: a double-blind, prospective, randomized placebo-controlled study. ( Bagheri Baravati, F; Dehghanpisheh, L; Eghbal, M; Vatankhah, P, 2021)
"Fentanyl-induced cough (FIC) usually occurs after the intravenous administration of fentanyl during general anaesthesia induction."9.34Comparing the different oxycodone doses of prevent oxycodone for prevention of preventing fentanyl-induced cough during induction of general anaesthesia. ( Cao, X; Dai, B, 2020)
"To compare the effects of intravenous (IV) lidocaine and fentanyl on the cough reflex and autonomic response during endotracheal intubation in dogs."9.34Comparison between intravenous lidocaine and fentanyl on cough reflex and sympathetic response during endotracheal intubation in dogs. ( Bravo, VR; Corletto, F; Palomba, N; Vettorato, E; Willis, R, 2020)
" Propofol with opioids has been recommended for gastroscopy sedation but the effects on cough reflex suppression remain unclear."9.24Effect of propofol combined with opioids on cough reflex suppression in gastroscopy: study protocol for a double-blind randomized controlled trial. ( Cao, YZ; Lu, X; Xia, J; Xie, J; Yin, N; Yuan, J, 2017)
"Fentanyl-induced cough (FIC) is unwanted in the patients requiring stable induction of general anesthesia."9.22Butorphanol suppresses fentanyl-induced cough during general anesthesia induction: A randomized, double-blinded, placebo-controlled clinical trial. ( Cheng, XY; Li, HB; Lun, XQ; Zhang, ZJ, 2016)
"This study was designed to investigate whether a priming dose of ketamine-dexmedetomidine can effectively suppress fentanyl-induced coughing (FIC)."9.19A priming dose of intravenous ketamine-dexmedetomidine suppresses fentanyl-induced coughing: a double-blind, randomized, controlled study. ( Hadi, SM; Ouyang, W; Saleh, AJ; Zhang, L, 2014)
"Fentanyl-induced cough is not an uncommon phenomenon during the induction of general anesthesia."9.16Effects of different priming doses of fentanyl on fentanyl-induced cough: a double-blind, randomized, controlled study. ( Gu, C; Li, F; Tang, Q; Wu, H; Zhou, M, 2012)
"The incidence of fentanyl-induced cough (FIC) during induction of general anesthesia varies around 40% and is undesirable."9.16Dexmedetomidine reduces the incidence of fentanyl-induced cough: a double-blind, randomized, and placebo-controlled study. ( Dai, RP; He, L; Xu, JM, 2012)
"An intravenous bolus of fentanyl often induces a cough reflex."9.16Priming dose of intravenous rocuronium suppresses fentanyl-induced coughing. ( Horng, HC; Liaw, WJ; Lin, BF; Lin, SL; Wang, HJ; Wang, TC; Wong, CS, 2012)
"The incidence of fentanyl-induced cough (FIC) occurs frequently during induction of general anesthesia, and methods to prevent it are needed."9.16Premedication with intravenous dexmedetomidine-midazolam suppresses fentanyl-induced cough. ( Dong, C; Lu, Y; Xu, R; Yu, J; Zhu, H, 2012)
"Although fentanyl suppresses tracheal tube-induced cough during anesthetic recovery, it has not been proven if its antitussive effect is dose dependent and complication free."9.15Dose-dependent attenuation by fentanyl on cough during emergence from general anesthesia. ( Choi, EM; Jeong, JJ; Lee, JR; Moon, BE; Na, S; Yoo, YC, 2011)
"Fentanyl is commonly used during anaesthesia and can cause fentanyl-induced cough (FIC)."9.15Effects of a priming dose of fentanyl during anaesthesia on the incidence and severity of fentanyl-induced cough in current, former and non-smokers. ( Cho, HJ; Im, KS; Jung, HJ; Kim, JB; Kim, JW; Lee, JM, 2011)
"To evaluate the suppressive effect of intravenous dezocine on fentanyl-induced cough during the induction of general anesthesia."9.15Effect of intravenous dezocine on fentanyl-induced cough during general anesthesia induction: a double-blinded, prospective, randomized, controlled trial. ( Cui, Z; Han, XP; Sun, ZT; Yang, CY; Zhang, J, 2011)
"To determine if fentanyl-induced cough was dose-dependent in children and whether it could affect tracheal intubation."9.14The frequency of fentanyl-induced cough in children and its effects on tracheal intubation. ( Han, JI; Kim, CH; Lee, GY; Lee, H, 2010)
"To explore the effect of intravenous injection rate and site of fentanyl on the incidence and onset time of fentanyl-induced cough."9.14[Intravenous injection rate and site of fentanyl affect the incidence and onset time of fentanyl-induced cough]. ( Chen, WT; Chen, YM; Gu, MN; Liang, SW, 2009)
"IV fentanyl en bolus can provoke cough reflex."9.14[Incidence and onset time of fentanyl-induced cough depends on the dose of IV fentanyl]. ( Fukuda, K; Handa, M; Hayashida, M; Ichinohe, T; Iida, K; Kaneko, Y; Kasahara, M; Koukita, Y; Saita, N; Urabe, A, 2009)
"Fentanyl-induced cough is not an uncommon condition during the induction of general anesthesia."9.14Effects of different priming doses of propofol on fentanyl-induced cough during anesthesia induction: a preliminary randomized controlled study. ( Qian, Y; Tang, Q; Wang, Z; Yang, J; Zhang, Q, 2010)
"To observe the effect of optimizing anesthetic injecting sequence during induction on fentanyl-induced coughing."9.14[Effect of optimizing anesthetic injecting sequence during induction on fentanyl-induced coughing]. ( Liu, B; Wang, L; Yao, JH; Zhou, DC; Zhu, JG; Zhu, JJ, 2010)
"We performed a randomised, double-blind study to evaluate the effect of the pre-emptive use of minimal dose intravenous fentanyl (25 microg) on the incidence of cough caused by a larger bolus of intravenous fentanyl."9.14The effect of pre-emptive use of minimal dose fentanyl on fentanyl-induced coughing. ( Chen, CW; Hsieh, SW; Hung, KC; Lin, VC; Weng, HC, 2010)
" fentanyl bolus is associated with coughing in 28-65% of patients."9.14A huffing manoeuvre, immediately before induction of anaesthesia, prevents fentanyl-induced coughing: a prospective, randomized, and controlled study. ( Ambesh, SP; Gupta, D; Singh, N; Singh, PK; Singh, U, 2010)
"The aim of the study was to investigate whether the incidence of cough after intravenous fentanyl depends on the speed of injection."9.13Fentanyl-induced cough does not depend on injection speed: a randomized study. ( Hopf, HB; Schäpermeier, U, 2008)
"To evaluate the effect of low-dose ketamine on fentanyl-induced cough."9.12Premedication with intravenous low-dose ketamine suppresses fentanyl-induced cough. ( Huh, BK; J Sheen, M; Lee, MS; Lin, SL; Wong, CS; Wu, CT; Yeh, CC, 2007)
"Patients in the clonidine group showed a significantly lower incidence of cough than those in the control group (17."9.12Pre-medication with intravenous clonidine suppresses fentanyl-induced cough. ( Cherng, CH; Horng, HC; Hsiao, KN; Huh, BK; Kuo, CP; Wong, CS; Wu, CT, 2007)
"Fentanyl is regularly used in clinical anesthesia practice but fentanyl-induced cough (FIC) will sometimes bother anesthesiologists."9.12Intravenous dexamethasone pretreatment reduces fentanyl-induced cough. ( Chen, FC; Cherng, CH; Horng, HC; Lee, MS; Lin, JA; Wong, CS; Yeh, CC, 2007)
"We compared the incidence and severity of cough following a bolus of sufentanil with that following fentanyl in 510 patients, randomly allocated to receive sufentanil 0."9.12Comparison of the incidence and severity of cough induced by sufentanil and fentanyl: a prospective, randomised, double-blind study. ( Agarwal, A; Gautam, S; Gupta, D; Nath, SS; Singh, U, 2007)
"IV lidocaine is effective in suppressing the cough reflex of tracheal intubation, extubation, bronchography, bronchoscopy, and laryngoscopy."9.11Intravenous lidocaine suppresses fentanyl-induced coughing: a double-blind, prospective, randomized placebo-controlled study. ( Agarwal, A; Lakra, A; Pandey, CK; Ranjan, R; Raza, M; Singh, PK; Singh, RB; Singh, U, 2004)
"To evaluate the minimal dose of lidocaine required for suppression of fentanyl-induced cough."9.11Intravenous lidocaine 0.5 mg.kg-1 effectively suppresses fentanyl-induced cough. ( Agarwal, A; Kumar, M; Lakra, A; Navkar, DV; Pandey, CK; Ranjan, R; Raza, M; Singh, PK; Singh, RB; Singh, U; Singhal, V, 2005)
"We designed this study to evaluate the effect of injection time and smoking on fentanyl-induced cough."9.11Prolonged injection time and light smoking decrease the incidence of fentanyl-induced cough. ( Lee, MS; Lin, JA; Lin, SL; Wong, CS; Wu, CT; Yeh, CC, 2005)
" Following iv fentanyl (2 micro g x kg(-1)) the incidence of cough was recorded and graded as mild (1-2), moderate (3-5) and severe (> 5) depending on the number of coughs observed."9.10Salbutamol, beclomethasone or sodium chromoglycate suppress coughing induced by iv fentanyl. ( Agarwal, A; Ambesh, S; Azim, A; Bose, N; Dhiraj, S; Sahu, D; Singh, U, 2003)
"To study the suppressive effect of inhalation of a selective beta 2-adrenergic bronchodilator terbutaline, and the effect of an intravenous anticholinergic, atropine, on fentanyl-induced coughing."9.08Terbutaline inhalation suppresses fentanyl-induced coughing. ( Chu, YC; Hsing, CH; Lui, PW, 1996)
"To evaluate whether different doses of intravenous lidocaine are effective at preventing fentanyl-induced cough (FIC), we searched PubMed, Scopus, Cochrane Library, EMBASE and Web of Science, according to predefined criteria, for all articles published until June 2017."8.98Prophylactic Intravenous Lidocaine at Different Doses for Fentanyl-Induced Cough (FIC): A Meta-Analysis. ( Gao, X; Guo, J; Huang, W; Li, S; Liu, X; Tan, W; Wang, Z, 2018)
"Fentanyl-induced cough (FIC) is often observed after intravenous bolus administration of fentanyl during anesthesia induction."8.90Pharmacological and nonpharmacological prevention of fentanyl-induced cough: a meta-analysis. ( Chae, YJ; Kim, JE; Kim, JY; Lee, YJ; Min, SK; Moon, BK, 2014)
" Sub-group analysis indicated a significant reduction in the incidence of both fentanyl-induced cough (FIC) and remifentanil-induced cough (RIC), but it appeared that lidocaine only alleviated the severity of FIC."8.90The impact of prophylactic intravenous lidocaine on opioid-induced cough: a meta-analysis of randomized controlled trials. ( Guo, R; Sun, L, 2014)
"Many reports have demonstrated that intravenous administration of a bolus of fentanyl at induction of anesthesia can cause coughing with varying degrees."8.90Fentanyl-induced cough--pathophysiology and prevention. ( El Baissari, MC; Siddik-Sayyid, SM; Taha, SK, 2014)
"BACKGROUND Fentanyl-induced cough (FIC) during general anesthesia induction and postoperative nausea and vomiting are common complications, yet the risk factors for FIC remain controversial."8.02Risk Factors for Fentanyl-Induced Cough Following General Anesthesia in Adults: A Retrospective Study from a Single Center in China. ( Chen, LH; Li, ST; Wang, H; Wang, HJ; Wang, Y; Xing, YA; Zhao, X, 2021)
"Postoperative nausea and vomiting (PONV) and fentanyl-induced cough (FIC) are two common anaesthesia-related events, which seem to have common risk factors."7.81Fentanyl-induced cough is a risk factor for postoperative nausea and vomiting. ( Chen, LK; Chen, SS; Chien, KL; Fan, SZ; Huang, CH; Leighton, BL; Li, CC; Yang, HJ, 2015)
"To determine how the probability of fentanyl-induced cough is affected by patient characteristics and/or anesthetic technique."7.73Identification of independent risk factors for fentanyl-induced cough. ( Dohi, S; Kasuya, Y; Murakami, T; Okumura, Y; Oshima, T, 2006)
"We designed a case-controlled matching study to investigate the correlation between fentanyl-induced coughing and airway hyperresponsiveness."7.71Fentanyl-induced coughing and airway hyperresponsiveness. ( Chiang, SC; Hsin, ST; Luk, HN; Tsou, CH; Wang, JH, 2002)
"Fentanyl is a strong µ-opioid analgesic which attenuates the stimulation of surgical invasion and tracheal intubation."6.84Swallowing action immediately before intravenous fentanyl at induction of anesthesia prevents fentanyl-induced coughing: a randomized controlled study. ( Fujimura, N; Sako, S; Tokunaga, S; Tsukamoto, M; Yokoyama, T; Yoshino, J, 2017)
"To assess the effects of intravenous (IV) fentanyl on cough reflex and quality of endotracheal intubation (ETI) in cats."5.69Effect of intravenous fentanyl on cough reflex and quality of endotracheal intubation in cats. ( Martín Bellido, V; Martínez I Ferré, B; McDonald, H; Vettorato, E, 2023)
" The time to extubation, respiratory complications, nausea, pain, and the number of patients receiving fentanyl were comparable between the groups."5.69The Impact of Head Elevation on Prevalence and Severity of Emergence Cough in Male Patients during Endotracheal Extubation. ( Kim, JE; Kim, JH; Lim, GM; Park, SJ; Park, SY, 2023)
" The purpose of this study is to investigate the efficacy of nebulized fentanyl citrate on dyspnea, cough, and throat pain in patients with COVID-19 and evaluate the safety with any potential adverse events."5.51Nebulized fentanyl for respiratory symptoms in patients with COVID-19 (ventanyl trial). ( Abujaber, AA; Al-Assaf, AA; Khatib, MY; Mohamed, AS; Nashwan, AJ; Shaikh, N; Tharayil, AGM; Wraidat, MAA, 2022)
"To compare the effects of intravenous (IV) lidocaine and fentanyl on the cough reflex and autonomic response during endotracheal intubation in dogs."5.34Comparison between intravenous lidocaine and fentanyl on cough reflex and sympathetic response during endotracheal intubation in dogs. ( Bravo, VR; Corletto, F; Palomba, N; Vettorato, E; Willis, R, 2020)
" Propofol with opioids has been recommended for gastroscopy sedation but the effects on cough reflex suppression remain unclear."5.24Effect of propofol combined with opioids on cough reflex suppression in gastroscopy: study protocol for a double-blind randomized controlled trial. ( Cao, YZ; Lu, X; Xia, J; Xie, J; Yin, N; Yuan, J, 2017)
"Fentanyl-induced cough (FIC) is unwanted in the patients requiring stable induction of general anesthesia."5.22Butorphanol suppresses fentanyl-induced cough during general anesthesia induction: A randomized, double-blinded, placebo-controlled clinical trial. ( Cheng, XY; Li, HB; Lun, XQ; Zhang, ZJ, 2016)
"Coughing was observed in six (12%) and ten (20%) in the fentanyl and control group, respectively (P = 0."5.20Does small-dose fentanyl improve perioperative outcomes in the ambulatory setting? A randomized, double-blind, placebo-controlled study. ( Elvir-Lazo, OL; Kariger, R; Khany, MM; Stern, A; Vuong, M; Wender, RH; White, PF; Yumul, R; Zaentz, AS, 2015)
"A dose of 1 mg/kg of tramadol administered intravenously 30 minutes before the expected extubation, compared with 1 μg/kg of fentanyl, decreased cough incidence, improved emergence quality, and provided stable hemodynamics."5.16Comparison between intraoperative fentanyl and tramadol to improve quality of emergence. ( Chan, SM; Cherng, CH; Hung, NK; Ju, DT; Lin, BF; Wu, CT; Yeh, CC, 2012)
"Although fentanyl suppresses tracheal tube-induced cough during anesthetic recovery, it has not been proven if its antitussive effect is dose dependent and complication free."5.15Dose-dependent attenuation by fentanyl on cough during emergence from general anesthesia. ( Choi, EM; Jeong, JJ; Lee, JR; Moon, BE; Na, S; Yoo, YC, 2011)
"We performed a randomised, double-blind study to evaluate the effect of the pre-emptive use of minimal dose intravenous fentanyl (25 microg) on the incidence of cough caused by a larger bolus of intravenous fentanyl."5.14The effect of pre-emptive use of minimal dose fentanyl on fentanyl-induced coughing. ( Chen, CW; Hsieh, SW; Hung, KC; Lin, VC; Weng, HC, 2010)
" with Steyn modification which includes five criteria; ease of laryngoscopy, degree of coughing, position of vocal cords, jaw relaxation, and limb movement and graded on a 4-point scale."5.12Comparative evaluation of different doses of propofol preceded by fentanyl on intubating conditions and pressor response during tracheal intubation without muscle relaxants. ( Gupta, A; Kale, S; Kaur, R; Malhotra, R, 2006)
"The incidence of typical airway irritation events was lower with fentanyl than with saline (cough, 2."5.12Fentanyl reduces desflurane-induced airway irritability following thiopental administration in children. ( Kim, C; Kim, H; Kim, S; Lee, J; Oh, Y; Park, H, 2006)
"The history of smoking and premedication did not influence the proportion of patients who had a cough response to fentanyl when administrated as first agent during induction in anesthesia."5.12The influence of premedication and smoking. ( Atsalakis, J; Dimitriou, V; Ioakimidou, A; Koursoumi, E; Saranteas, T; Spyrou, A; Stranomiti, J, 2006)
"We compared the incidence and severity of cough following a bolus of sufentanil with that following fentanyl in 510 patients, randomly allocated to receive sufentanil 0."5.12Comparison of the incidence and severity of cough induced by sufentanil and fentanyl: a prospective, randomised, double-blind study. ( Agarwal, A; Gautam, S; Gupta, D; Nath, SS; Singh, U, 2007)
"To evaluate the minimal dose of lidocaine required for suppression of fentanyl-induced cough."5.11Intravenous lidocaine 0.5 mg.kg-1 effectively suppresses fentanyl-induced cough. ( Agarwal, A; Kumar, M; Lakra, A; Navkar, DV; Pandey, CK; Ranjan, R; Raza, M; Singh, PK; Singh, RB; Singh, U; Singhal, V, 2005)
" Following iv fentanyl (2 micro g x kg(-1)) the incidence of cough was recorded and graded as mild (1-2), moderate (3-5) and severe (> 5) depending on the number of coughs observed."5.10Salbutamol, beclomethasone or sodium chromoglycate suppress coughing induced by iv fentanyl. ( Agarwal, A; Ambesh, S; Azim, A; Bose, N; Dhiraj, S; Sahu, D; Singh, U, 2003)
" Patients with only mild pain when coughing during thoracic epidural infusion of about 10 ml per hour of bupivacaine 1 mg x ml(-1), fentanyl 2 microg x ml(-1), and adrenaline 2 microg x ml(-1) were included."5.09Epidural fentanyl markedly improves thoracic epidural analgesia in a low-dose infusion of bupivacaine, adrenaline and fentanyl. A randomized, double-blind crossover study with and without fentanyl. ( Breivik, H; Niemi, G, 2001)
"The aim of this study was to investigate the incidence of pre-induction coughing, after an iv bolus of fentanyl."5.07Tussive effect of a fentanyl bolus. ( Jong, W; Lee, TL; Phua, WT; Teh, BT; Tweed, WA, 1991)
" Sub-group analysis indicated a significant reduction in the incidence of both fentanyl-induced cough (FIC) and remifentanil-induced cough (RIC), but it appeared that lidocaine only alleviated the severity of FIC."4.90The impact of prophylactic intravenous lidocaine on opioid-induced cough: a meta-analysis of randomized controlled trials. ( Guo, R; Sun, L, 2014)
"Fentanyl-induced cough (FIC) is often observed after intravenous bolus administration of fentanyl during anesthesia induction."4.90Pharmacological and nonpharmacological prevention of fentanyl-induced cough: a meta-analysis. ( Chae, YJ; Kim, JE; Kim, JY; Lee, YJ; Min, SK; Moon, BK, 2014)
"BACKGROUND Fentanyl-induced cough (FIC) during general anesthesia induction and postoperative nausea and vomiting are common complications, yet the risk factors for FIC remain controversial."4.02Risk Factors for Fentanyl-Induced Cough Following General Anesthesia in Adults: A Retrospective Study from a Single Center in China. ( Chen, LH; Li, ST; Wang, H; Wang, HJ; Wang, Y; Xing, YA; Zhao, X, 2021)
"Postoperative nausea and vomiting (PONV) and fentanyl-induced cough (FIC) are two common anaesthesia-related events, which seem to have common risk factors."3.81Fentanyl-induced cough is a risk factor for postoperative nausea and vomiting. ( Chen, LK; Chen, SS; Chien, KL; Fan, SZ; Huang, CH; Leighton, BL; Li, CC; Yang, HJ, 2015)
"To determine how the probability of fentanyl-induced cough is affected by patient characteristics and/or anesthetic technique."3.73Identification of independent risk factors for fentanyl-induced cough. ( Dohi, S; Kasuya, Y; Murakami, T; Okumura, Y; Oshima, T, 2006)
"We designed a case-controlled matching study to investigate the correlation between fentanyl-induced coughing and airway hyperresponsiveness."3.71Fentanyl-induced coughing and airway hyperresponsiveness. ( Chiang, SC; Hsin, ST; Luk, HN; Tsou, CH; Wang, JH, 2002)
"The incidence of myoclonus was significantly lower in the nalmefene group (8."3.30Low-dose nalmefene pretreatment reduces etomidate-induced myoclonus: A randomized, double-blind controlled trial. ( Cao, H; Dai, F; Liu, Y; Lu, H; Shan, G; Yin, D, 2023)
"The incidence of gagging (P = 0."2.68Comparison of propofol versus thiopentone with midazolam or lidocaine to facilitate laryngeal mask insertion. ( Bapat, P; Jago, RH; Joshi, RN; Young, E, 1996)
"Therefore, postoperative pain control after OLT should be carefully titrated according to the severity of the liver disease."1.38The relationship between postoperative intravenous patient-controlled fentanyl analgesic requirements and severity of liver disease. ( Gwak, MS; Jang, CH; Kim, GS; Ko, JS; Lee, SK; Shin, YH, 2012)

Research

Studies (96)

TimeframeStudies, this research(%)All Research%
pre-19902 (2.08)18.7374
1990's13 (13.54)18.2507
2000's31 (32.29)29.6817
2010's39 (40.63)24.3611
2020's11 (11.46)2.80

Authors

AuthorsStudies
Sirohiya, P1
Kumar, V1
Mittal, S1
Gupta, N1
Garg, R1
Bharati, SJ1
Mishra, S1
Hadda, V1
Mohan, A1
Sagiraju, HKR1
Bhatnagar, S1
Madan, K1
Shaikh, N1
Khatib, MY1
Wraidat, MAA1
Mohamed, AS1
Al-Assaf, AA1
Tharayil, AGM1
Abujaber, AA1
Nashwan, AJ1
Phuvachoterojanaphokin, N1
Watanaboonyongcharoen, G1
Jinawong, S1
Munjupong, S1
Martín Bellido, V1
Martínez I Ferré, B1
McDonald, H1
Vettorato, E2
Shan, G1
Lu, H1
Dai, F1
Liu, Y1
Yin, D1
Cao, H1
Lim, GM1
Park, SJ1
Park, SY1
Kim, JH1
Kim, JE2
Shim, JS1
Song, WJ1
Morice, AH1
Bravo, VR1
Palomba, N1
Corletto, F1
Willis, R1
Dai, B1
Cao, X1
Dehghanpisheh, L1
Eghbal, M1
Bagheri Baravati, F1
Vatankhah, P1
Zhao, X1
Wang, H1
Wang, HJ2
Wang, Y2
Xing, YA1
Li, ST1
Chen, LH1
Ho, CN1
Hung, KC4
Yin, N1
Xia, J1
Cao, YZ1
Lu, X1
Yuan, J1
Xie, J1
Tsukamoto, M2
Yokoyama, T2
Naldan, ME1
Arslan, Z1
Ay, A1
Yayık, AM1
Tan, W1
Li, S1
Liu, X1
Gao, X1
Huang, W1
Guo, J1
Wang, Z2
Min, SK1
Chae, YJ1
Lee, YJ1
Moon, BK1
Kim, JY1
De Oliveira, GS1
Fitzgerald, PC1
Ahmad, S1
Marcus, RJ1
McCarthy, RJ1
Sun, L2
Guo, R1
El Baissari, MC1
Taha, SK1
Siddik-Sayyid, SM1
White, PF1
Elvir-Lazo, OL1
Zaentz, AS1
Kariger, R1
Yumul, R1
Khany, MM1
Stern, A1
Vuong, M1
Wender, RH1
Saleh, AJ1
Zhang, L1
Hadi, SM1
Ouyang, W1
Murphy, GS1
Szokol, JW1
Avram, MJ1
Greenberg, SB1
Marymont, JH1
Shear, T1
Parikh, KN1
Patel, SS1
Gupta, DK1
Li, CC1
Chen, SS1
Huang, CH1
Chien, KL1
Yang, HJ1
Fan, SZ1
Leighton, BL1
Chen, LK1
Kelly, HE1
Shaw, GM1
Brett, CN1
Greenwood, FM1
Huckabee, ML1
Allen, G1
Cheng, XY1
Lun, XQ1
Li, HB1
Zhang, ZJ1
Peringathara, B1
Robinson, S1
Sako, S1
Tokunaga, S1
Yoshino, J1
Fujimura, N1
Schäpermeier, U1
Hopf, HB1
Chen, YM1
Chen, WT1
Liang, SW1
Gu, MN1
Iida, K2
Handa, M1
Fukuda, K2
Saita, N1
Kasahara, M1
Koukita, Y2
Urabe, A1
Hayashida, M1
Ichinohe, T1
Kaneko, Y1
Uvelin, A1
Rakic, G1
Tang, Q2
Qian, Y1
Zhang, Q1
Yang, J1
Chen, CW1
Lin, VC1
Weng, HC1
Hsieh, SW1
Ambesh, SP1
Singh, N1
Gupta, D2
Singh, PK3
Singh, U5
Han, JI1
Lee, H1
Kim, CH1
Lee, GY1
Schäfer, M1
Keilig, S1
Brack, A1
Kranke, P1
Mizutani, K1
Elcock, DH1
Inomata, S1
Maeda, T1
Shimizu, T1
Satsumae, T1
Tanaka, M1
Wang, L1
Yao, JH1
Zhu, JJ1
Liu, B2
Zhu, JG1
Zhou, DC1
Sun, ZT1
Yang, CY1
Cui, Z1
Zhang, J1
Han, XP1
Makkar, JK1
Ghai, B1
Bhardwaj, N1
Wig, J1
Lin, BF2
Ju, DT1
Cherng, CH3
Hung, NK1
Yeh, CC4
Chan, SM1
Wu, CT4
Yoo, YC1
Na, S1
Jeong, JJ1
Choi, EM1
Moon, BE1
Lee, JR1
Sun, Q1
Zhou, W1
Wu, B1
Ji, MH1
Peng, YG1
Jung, HJ1
Kim, JB1
Im, KS1
Cho, HJ1
Kim, JW1
Lee, JM1
He, L1
Xu, JM1
Dai, RP1
Yu, J1
Lu, Y1
Dong, C1
Zhu, H1
Xu, R1
Ko, JS1
Shin, YH1
Gwak, MS1
Jang, CH1
Kim, GS1
Lee, SK1
Gu, C1
Zhou, M1
Wu, H1
Li, F1
Horng, HC3
Wang, TC1
Lin, SL3
Liaw, WJ1
Wong, CS5
Tsou, CH1
Luk, HN1
Chiang, SC1
Hsin, ST1
Wang, JH1
Agarwal, A4
Azim, A1
Ambesh, S1
Bose, N1
Dhiraj, S1
Sahu, D1
Pandey, CK2
Raza, M2
Ranjan, R2
Lakra, A2
Singh, RB2
Singhal, V1
Kumar, M1
Navkar, DV1
Schlimp, CJ1
Wiedermann, FJ1
Ortiz-Gómez, JR1
Carrascosa, F1
Pérez-Cajaraville, JJ1
Percaz-Bados, JA1
Añez, C1
Lin, JA2
Lee, MS3
Gupta, A1
Kaur, R1
Malhotra, R1
Kale, S1
Oshima, T1
Kasuya, Y1
Okumura, Y1
Murakami, T1
Dohi, S1
Lee, J1
Oh, Y1
Kim, C1
Kim, S1
Park, H1
Kim, H1
Dimitriou, V1
Spyrou, A1
Ioakimidou, A1
Stranomiti, J1
Koursoumi, E1
Atsalakis, J1
Saranteas, T1
Huh, BK2
J Sheen, M1
Hsiao, KN1
Kuo, CP1
Hohlrieder, M1
Tiefenthaler, W1
Klaus, H1
Gabl, M1
Kavakebi, P1
Keller, C1
Benzer, A1
Yu, H1
Yang, XY1
Zhang, X1
Li, Q1
Zhu, T1
Chen, FC1
Gautam, S1
Nath, SS1
Ishiyama, T1
Iijima, T1
Sugawara, T1
Shibuya, K1
Sato, H1
Terada, Y1
Ichikawa, M1
Sessler, DI1
Matsukawa, T1
Koh, KF1
Chen, FG1
Schwender, D1
Faber-Züllig, E1
Klasing, S1
Pöppel, E1
Peter, K1
Bapat, P1
Joshi, RN1
Young, E1
Jago, RH1
Lui, PW1
Hsing, CH1
Chu, YC1
Sanderson, PM1
Inagaki, Y1
Shindo, H1
Mashimo, T1
Yoshiya, I1
Sjöström, S1
Bläss, J1
Niemi, G3
Breivik, H3
Carrero Cardenal, EJ1
Valero Castell, R1
Roux Carmona, C1
Lapena Bayo, C1
Ortells Ribé, J1
Artigas Rubio, X1
Beebe, DS1
Tran, P1
Bragg, M1
Stillman, A1
Truwitt, C1
Belani, KG1
Olympio, MA1
Youngblood, BL1
James, RL1
Kong, CF1
Chew, ST1
Ip-Yam, PC1
Tweed, WA2
Dakin, D1
D'Olimpio, J1
Tammisto, T1
Mattila, MJ1
Gin, T1
Chui, PT1
Phua, WT1
Teh, BT1
Jong, W1
Lee, TL1
Böhrer, H1
Fleischer, F1
Werning, P1
Ananthanarayan, C1
d' Hollander, AA1
Monteny, E1
Dewachter, B1
Sanders, M1
Dubois-Primo, J1

Clinical Trials (14)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Quality of Recovery After General Anesthesia With Desflurane and Sevoflurane in Endoscopic Ureteral Lithotripsy[NCT04712162]60 participants (Actual)Interventional2019-11-19Completed
The Effect of Desflurane vs Sevoflurane on Perioperative Respiratory Complications in Laryngeal Mask Airway Anesthesia: A Prospective Randomized Double-blinded Control Study[NCT03006250]Phase 4220 participants (Anticipated)Interventional2016-08-31Recruiting
Randomized, Double-Blinded, Placebo-Controlled Study to Evaluate the Effect of Fentanyl on the Incidence of Coughing and Recovery After Propofol-Desflurane Anesthesia With an LMA for Airway Management[NCT01368809]Phase 4100 participants (Actual)Interventional2011-06-30Completed
Pharmacokinetics of Methadone in Adults Undergoing Cardiac Surgery With Extracorporeal Circulation[NCT05075265]30 participants (Anticipated)Observational2021-10-02Not yet recruiting
Intraoperative Methadone for Postoperative Pain in Patients Undergoing Tonsillectomy - a Randomized Controlled Trial[NCT05445856]Phase 4130 participants (Anticipated)Interventional2022-11-28Recruiting
Clinical Effectiveness and Safety of Intraoperative Methadone in Patients Undergoing Laparoscopic Hysterectomy: a Prospective, Double-blind, Randomised Controlled Trial[NCT03908060]126 participants (Actual)Interventional2019-05-06Active, not recruiting
Single-dose Intraoperative Methadone for Early Ambulation and Sustained Pain Control in Spinal Fusion Surgery Patients[NCT02989597]Phase 410 participants (Actual)Interventional2017-07-29Terminated (stopped due to Due to personnel loss and logistical issues the study was unable to be completed as planned.)
The Effect of Methadone vs. Fentanyl Administration on Postoperative Pain Control in Pediatric Patients Undergoing Cardiac Surgery: A Randomized, Double-Blinded Controlled Trial[NCT02747875]26 participants (Actual)Interventional2016-09-30Terminated (stopped due to Drug Shortage)
Effect of Head Position on Minimum Alveolar Concentration of Endotracheal Intubation(MACEI)of Sevoflurane in Children With Obstructive Airway[NCT03522402]38 participants (Anticipated)Interventional2018-01-01Enrolling by invitation
Effect of Single Dose of Tramadol on Extubation Response and Quality of Emergence(Cough and Nausea Vomiting) Following Supratentorial Intracranial Surgery[NCT02964416]Phase 480 participants (Actual)Interventional2016-03-31Completed
Effect of Tramadol on Postoperative Sore Throat in Thyroid Surgery Under General Anesthesia With Endotracheal Intubation: A Randomized Controlled Trial[NCT04991493]Phase 4168 participants (Anticipated)Interventional2021-09-10Recruiting
Can Propofol Reduce Respiratory Adverse Events During Extubation in Children With Tonsillectomy? A Prospective Randomized Controlled Study[NCT05769842]240 participants (Anticipated)Interventional2023-11-01Not yet recruiting
Effect of Two Plasma Concentrations of Remifentanil Through Target Controlled Anesthesia on Frequency and Intensity of Coughing During Extubation: Randomized Controlled Clinical Trial[NCT02711904]Phase 4110 participants (Actual)Interventional2011-01-31Completed
Efficiency of Intravenous Lidocaine to Reduce Coughing and the Hemodynamic Changes Associated to Tracheal Extubation[NCT03731429]Phase 4144 participants (Anticipated)Interventional2019-04-05Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Incidence of Coughing

during the perioperative period (insertion of an LMA device, maintenance of anesthesia, and emergence from general anesthesia) for ambulatory surgery procedures. (NCT01368809)
Timeframe: one day

Interventionparticipants (Number)
Fentanyl10
Saline Solution6

Incidence of Nausea and Vomiting

Postoperative nausea and vomiting using a Verbal Rating Scale (0-10) at PACU (post-anesthesia care unit. (NCT01368809)
Timeframe: 1 day

Interventionparticipants (Number)
Fentanyl2
Saline Solution4

Postoperative Pain

"Postoperative pain measured using a Verbal Rating Scale (VRS) at post-anesthesia care unit (PACU), (90 minutes after arriving).~Postoperative pain VRS scores: 0 = none pain to 10 = intolerable pain." (NCT01368809)
Timeframe: one day

InterventionScores on a scale (Mean)
Fentanyl1.5
Saline Solution1.5

Total Opioid Dose, in Morphine Equivalents, in the First 24 Hours After Pediatric Cardiac Bypass Surgery.

The distribution of the total opioid dose in the first 24 hours will be evaluated by randomization group (methadone vs. fentanyl) and differences between groups will be tested. It is hypothesized that compared to fentanyl, methadone administered intraoperative will result in a significantly lower total opioid dose (morphine or oxycodone) during the first 24 hour postoperative period. Assuming no difference between the two treatment strategies in the population, a total sample size of 52 in each group will provide 80% power to detect an effect size of 0.1. Significance will be measured as a 30% reduction in postoperative pain requirement. (NCT02747875)
Timeframe: 24 hours

Interventionmg postop morphine equivelant 24hr (Mean)
Control - Fentanyl0.55
Treatment - Methadone0.48

Opioid-related Adverse Events Including: Respiratory Failure, Cardiovascular Instability, and Postoperative Nausea and Vomiting

Opioid-related adverse events will be monitored closely and a secondary analysis will compare the incidence of side effects between the two groups during the first 24-hour postoperative period. The Pearson's contingency chi-square test will be used to evaluate any differences between the randomization groups in opioid-related adverse events during the first 24-hour postoperative period. (NCT02747875)
Timeframe: 24 hours

,
Interventionevents (Mean)
Ondansetron DosesEmesis EpisodesHypoventilation EpisodesArrhythmias
Control - Fentanyl3.812.7200
Treatment - Methadone3.432.0800

Measure the Quality of Emergence From General Anaesthesia by Measuring the Frequency of Laryngospasm and Bronchospasm.

If there is any episode of bronchospasm or laryngospasm, it will be noted if it occured during emergence and for 6 hours post operatively. Absence of it will be considered as smooth emergence (NCT02964416)
Timeframe: at the time of extubation till 6 hours postoperatively

InterventionNumber of Patients (Number)
Tramadol0
Placebo0

Effect of Tramadol on Quality of Emergence Measured by Extubation Response Through Mointoring Requirement of Analgesia

Requirement of analgesia will be recorded at recovery room, 2, 4 and 6 hours postoperatively. If there is any need of analgesic, it will be noted and will be considered as one of the determinants of poor quality of emergence. (NCT02964416)
Timeframe: At Recovery room, 2, 4 and 6 hours postoperatively

,
InterventionParticipants (Count of Participants)
Recovery Room2h4h6h
Placebo32347
Tramadol51536

Effect of Tramadol on Quality of Emergence Measured by Extubation Response Through Monitoring Convulsions

Convulsions will be recorded at Recovery Room, 2, 4 and 6 hours postoperatively.If there is any episode of convulsion, it will be noted. Absence of it will be considered as smooth emergence. (NCT02964416)
Timeframe: at Recovery Room, 2, 4 and 6 hours postoperatively

,
InterventionParticipants (Count of Participants)
Recovery Room2h4h6h
Placebo0000
Tramadol0010

Effect of Tramadol on Quality of Emergence Measured by Extubation Response Through Monitoring GCS

"Post operative Glasgow Coma Scale (GCS) will be recorded at Recovery Room, 2, 4 and 6 hours postoperatively. If there is any deterioration in GCS less than 8/15, Patients will be intubated.~GCS categories <8 Low GCS 9-12 Intermediate GCS 13-15 Full GCS" (NCT02964416)
Timeframe: at Recovery Room, 2, 4 and 6 hours postoperatively

,
InterventionNumber of Patients (Number)
Recovery Room : <8Recovery Room : 9-12Recovery Room : 13-152h : <82h : 9-122h : 13-154h : <84h : 9-124h : 13-156h : <86h : 9-126h : 13-15
Placebo0041014010401040
Tramadol0138013800390039

Effect of Tramadol on Quality of Emergence Measured by Extubation Response Through Monitoring PONV

Post operative nausea vomiting will be recorded at RR, 2, 4 and 6 hours postoperatively. If there is any episode of PONV it will be noted. Absence of it will be considered as smooth emergence (NCT02964416)
Timeframe: at Recovery Room , 2, 4 and 6 hours postoperatively

,
InterventionParticipants (Count of Participants)
Recovery Room2h4h6h
Placebo0311
Tramadol0300

Haemodynamic Parameters at the Time of Emergence and Postextubation

Diastolic blood pressure will be recorded at 1 minute before giving the reversal (glycopyrolate and neostigmine) and then 1,2,5,10,20,30 minutes ,1,2,4 and 6 hours after extubation. If values of blood pressure rise more than 20% from baseline values injection Metoprolol 1mg (beta blocker) bolus will be used and titrated according to response. The study will end at 6 hours post extubation. (NCT02964416)
Timeframe: Diastolic BP from the time of extubation till 6 hours post operatively

,
Interventionmm Hg (Mean)
Base line1min Before Extubation1min After Extubation2 min5min10min20min30min1h2h4h6h
Placebo77.8378.6585.7882.4178.5978.3276.7376.9375.3375.8978.0074.89
Tramadol75.9277.3083.9779.1978.6877.3778.1977.1476.3975.7174.8575.26

Haemodynamic Parameters at the Time of Emergence and Postextubation

Heart rate will be recorded at 1 minute before giving the reversal (glycopyrolate and neostigmine) and then 1,2,5,10,20,30 minutes ,1,2,4 and 6 hours after extubation. If haemodynamic values of heart rate rise more than 20% from baseline values injection Metoprolol 1mg (beta blocker) bolus will be used and titrated according to response. The study will end at 6 hours post extubation. (NCT02964416)
Timeframe: HR from the time of extubation till 6 hours post operatively

,
Interventionbpm (Mean)
Baseline1min Before Extubation1min After Extubation2 min5min10min20min30min1h2h4h6h
Placebo79.3791.4198.5493.5090.0086.7083.3884.1082.4681.9781.2378.20
Tramadol82.2689.3093.6189.6186.2786.2682.4481.9279.5380.0378.9479.65

Haemodynamic Parameters at the Time of Emergence and Postextubation

Systolic blood pressure will be recorded at 1 minute before giving the reversal (glycopyrolate and neostigmine) and then 1,2,5,10,20,30 minutes ,1,2,4 and 6 hours after extubation. If values of blood pressure rise more than 20% from baseline values injection Metoprolol 1mg (beta blocker) bolus will be used and titrated according to response. The study will end at 6 hours post extubation. (NCT02964416)
Timeframe: Systolic BP from the time of extubation till 6 hours post operatively

,
Interventionmm Hg (Mean)
Baseline1min Before Extubation1min After Extubation2 min5min10min20min30min1h2h4h6h
Placebo132.34134.29143.70139.77133.37131.59133.15132.10129.80125.74125.81122.61
Tramadol128.55132.63141.81134.89130.05126.95127.86127.19128.11127.76127.35122.97

Measure the Quality of Emergence From General Anaesthesia by Measuring the Frequency of Episodes of Denaturation

"If there is any episodes of denaturation (Oxygen saturation <92%), it will be noted it it is occurring during emergence.~Absence of it will be considered as smooth emergence" (NCT02964416)
Timeframe: at the time of extubation

,
InterventionParticipants (Count of Participants)
at resumption of spontaneous breathingat the time of obeying of verbal commandsat the time of cuff deflationat the time of extubation2 min after extubation
Placebo00000
Tramadol00000

Measure the Quality of Emergence From General Anaesthesia by Measuring the Frequency of Cough on Cough Scale.

"Cough will be described on following scale 5 = No coughing or straining, 4 = Very smooth minimal coughing, 3 = Moderate coughing, 2 = Marked coughing or straining,~1 = Poor extubation~Cough will be recorded on the above mentioned scale by resident/consultant at following time intervals of emergence~At resumption of spontaneous breathing,~Ability to respond to verbal commands~At cuff deflation~At extubation~2 minutes after extubation. It will be noted if it occurs during emergence at the above mentioned time intervals. Absence of it will be considered as smooth emergence." (NCT02964416)
Timeframe: Cough at the time of emergence

InterventionParticipants (Count of Participants)
At resumption of spontaneous breathing72201515At resumption of spontaneous breathing72201516Ability to respond to verbal commands72201516Ability to respond to verbal commands72201515At cuff deflation72201516At cuff deflation72201515At extubation72201516At extubation722015152 minutes after extubation722015152 minutes after extubation72201516
Poor extubationMarked coughing or strainingModerate coughingVery smooth minimal coughingNo coughing or straining
Tramadol33
Placebo36
Placebo0
Tramadol1
Placebo1
Tramadol3
Placebo2
Tramadol34
Placebo37
Placebo3
Placebo4
Placebo33
Tramadol4
Placebo6
Tramadol32
Placebo32
Tramadol2
Tramadol0
Tramadol36

Reviews

6 reviews available for fentanyl and Cough

ArticleYear
Drug-Induced Cough.
    Physiological research, 2020, 03-27, Volume: 69, Issue:Suppl 1

    Topics: Analgesics, Opioid; Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Chr

2020
Prophylactic Intravenous Lidocaine at Different Doses for Fentanyl-Induced Cough (FIC): A Meta-Analysis.
    Scientific reports, 2018, 07-02, Volume: 8, Issue:1

    Topics: Administration, Intravenous; Adult; Child; Cough; Fentanyl; Humans; Lidocaine; Treatment Outcome

2018
Pharmacological and nonpharmacological prevention of fentanyl-induced cough: a meta-analysis.
    Journal of anesthesia, 2014, Volume: 28, Issue:2

    Topics: Administration, Intravenous; Adrenergic Agonists; Adult; Anesthetics, Intravenous; Anesthetics, Loca

2014
The impact of prophylactic intravenous lidocaine on opioid-induced cough: a meta-analysis of randomized controlled trials.
    Journal of anesthesia, 2014, Volume: 28, Issue:3

    Topics: Administration, Intravenous; Adult; Analgesics, Opioid; Anesthetics, Local; Cough; Female; Fentanyl;

2014
Fentanyl-induced cough--pathophysiology and prevention.
    Middle East journal of anaesthesiology, 2014, Volume: 22, Issue:5

    Topics: Anesthetics, Intravenous; Cough; Fentanyl; Humans

2014
Contemporary drug therapy in palliative care: new directions.
    Cancer investigation, 2001, Volume: 19, Issue:4

    Topics: Adrenal Cortex Hormones; Analgesics; Anorexia; Antiemetics; Antitussive Agents; Cachexia; Cough; Dru

2001

Trials

63 trials available for fentanyl and Cough

ArticleYear
Dexmedetomidine Versus Midazolam for Sedation During Medical Thoracoscopy: A Pilot Randomized-Controlled Trial (RCT).
    Journal of bronchology & interventional pulmonology, 2022, Oct-01, Volume: 29, Issue:4

    Topics: Analgesics, Opioid; Conscious Sedation; Cough; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Seda

2022
Nebulized fentanyl for respiratory symptoms in patients with COVID-19 (ventanyl trial).
    Medicine, 2022, Jan-28, Volume: 101, Issue:4

    Topics: Administration, Inhalation; Adolescent; Adult; Aged; Analgesics, Opioid; Clinical Trials, Phase III

2022
Low-dose lidocaine attenuates fentanyl-induced cough: A double-blind randomized controlled trial.
    European journal of clinical pharmacology, 2022, Volume: 78, Issue:5

    Topics: Anesthesia, General; Anesthetics, Local; Cough; Double-Blind Method; Fentanyl; Humans; Lidocaine; Pr

2022
Effect of intravenous fentanyl on cough reflex and quality of endotracheal intubation in cats.
    Veterinary anaesthesia and analgesia, 2023, Volume: 50, Issue:3

    Topics: Anesthesia, General; Anesthetics, Intravenous; Animals; Apnea; Cat Diseases; Cats; Cough; Dexmedetom

2023
Low-dose nalmefene pretreatment reduces etomidate-induced myoclonus: A randomized, double-blind controlled trial.
    Medicine, 2023, Sep-08, Volume: 102, Issue:36

    Topics: Anesthesia, General; Cough; Drug-Related Side Effects and Adverse Reactions; Etomidate; Fentanyl; Hu

2023
The Impact of Head Elevation on Prevalence and Severity of Emergence Cough in Male Patients during Endotracheal Extubation.
    Medical science monitor : international medical journal of experimental and clinical research, 2023, Nov-30, Volume: 29

    Topics: Airway Extubation; Cough; Fentanyl; Humans; Intubation, Intratracheal; Male; Pain; Prevalence

2023
Comparison between intravenous lidocaine and fentanyl on cough reflex and sympathetic response during endotracheal intubation in dogs.
    Veterinary anaesthesia and analgesia, 2020, Volume: 47, Issue:4

    Topics: Anesthetics, Intravenous; Animals; Autonomic Nervous System; Blood Pressure; Cough; Dog Diseases; Do

2020
Comparing the different oxycodone doses of prevent oxycodone for prevention of preventing fentanyl-induced cough during induction of general anaesthesia.
    International journal of clinical practice, 2020, Volume: 74, Issue:12

    Topics: Adult; Aged; Anesthesia, General; Cough; Fentanyl; Humans; Middle Aged; Oxycodone; Pharmaceutical Pr

2020
Comparison of lidocaine, huffing maneuver and combination of both in prevention fentanyl induced cough before induction of anesthesia: a double-blind, prospective, randomized placebo-controlled study.
    BMC anesthesiology, 2021, 03-27, Volume: 21, Issue:1

    Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Anesthetics, Local; Cough; Double-Blind Method

2021
Effect of propofol combined with opioids on cough reflex suppression in gastroscopy: study protocol for a double-blind randomized controlled trial.
    BMJ open, 2017, Sep-01, Volume: 7, Issue:9

    Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Antitussive Agents; Bridged Bicyclo Compounds, Heterocy

2017
Comparison of Lidocaine and Atropine on Fentanyl-Induced Cough: A Randomized Controlled Study.
    Journal of investigative surgery : the official journal of the Academy of Surgical Research, 2019, Volume: 32, Issue:5

    Topics: Anesthesia; Anesthetics, Local; Atropine; Child; Child, Preschool; Cough; Female; Fentanyl; Humans;

2019
Desflurane/fentanyl compared with sevoflurane/fentanyl on awakening and quality of recovery in outpatient surgery using a laryngeal mask airway: a randomized, double-blinded controlled trial.
    Journal of clinical anesthesia, 2013, Volume: 25, Issue:8

    Topics: Adult; Ambulatory Surgical Procedures; Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics,

2013
Desflurane/fentanyl compared with sevoflurane/fentanyl on awakening and quality of recovery in outpatient surgery using a laryngeal mask airway: a randomized, double-blinded controlled trial.
    Journal of clinical anesthesia, 2013, Volume: 25, Issue:8

    Topics: Adult; Ambulatory Surgical Procedures; Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics,

2013
Desflurane/fentanyl compared with sevoflurane/fentanyl on awakening and quality of recovery in outpatient surgery using a laryngeal mask airway: a randomized, double-blinded controlled trial.
    Journal of clinical anesthesia, 2013, Volume: 25, Issue:8

    Topics: Adult; Ambulatory Surgical Procedures; Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics,

2013
Desflurane/fentanyl compared with sevoflurane/fentanyl on awakening and quality of recovery in outpatient surgery using a laryngeal mask airway: a randomized, double-blinded controlled trial.
    Journal of clinical anesthesia, 2013, Volume: 25, Issue:8

    Topics: Adult; Ambulatory Surgical Procedures; Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics,

2013
Does small-dose fentanyl improve perioperative outcomes in the ambulatory setting? A randomized, double-blind, placebo-controlled study.
    Acta anaesthesiologica Scandinavica, 2015, Volume: 59, Issue:1

    Topics: Adult; Ambulatory Surgical Procedures; Analgesics, Opioid; Cough; Double-Blind Method; Female; Fenta

2015
A priming dose of intravenous ketamine-dexmedetomidine suppresses fentanyl-induced coughing: a double-blind, randomized, controlled study.
    Upsala journal of medical sciences, 2014, Volume: 119, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Cough; Dexmedetomidine; Double-Blind Method; Female; F

2014
Intraoperative Methadone for the Prevention of Postoperative Pain: A Randomized, Double-blinded Clinical Trial in Cardiac Surgical Patients.
    Anesthesiology, 2015, Volume: 122, Issue:5

    Topics: Aged; Analgesics, Opioid; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cough; Double-Blind M

2015
Intraoperative Methadone for the Prevention of Postoperative Pain: A Randomized, Double-blinded Clinical Trial in Cardiac Surgical Patients.
    Anesthesiology, 2015, Volume: 122, Issue:5

    Topics: Aged; Analgesics, Opioid; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cough; Double-Blind M

2015
Intraoperative Methadone for the Prevention of Postoperative Pain: A Randomized, Double-blinded Clinical Trial in Cardiac Surgical Patients.
    Anesthesiology, 2015, Volume: 122, Issue:5

    Topics: Aged; Analgesics, Opioid; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cough; Double-Blind M

2015
Intraoperative Methadone for the Prevention of Postoperative Pain: A Randomized, Double-blinded Clinical Trial in Cardiac Surgical Patients.
    Anesthesiology, 2015, Volume: 122, Issue:5

    Topics: Aged; Analgesics, Opioid; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cough; Double-Blind M

2015
Intraoperative Methadone for the Prevention of Postoperative Pain: A Randomized, Double-blinded Clinical Trial in Cardiac Surgical Patients.
    Anesthesiology, 2015, Volume: 122, Issue:5

    Topics: Aged; Analgesics, Opioid; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cough; Double-Blind M

2015
Intraoperative Methadone for the Prevention of Postoperative Pain: A Randomized, Double-blinded Clinical Trial in Cardiac Surgical Patients.
    Anesthesiology, 2015, Volume: 122, Issue:5

    Topics: Aged; Analgesics, Opioid; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cough; Double-Blind M

2015
Intraoperative Methadone for the Prevention of Postoperative Pain: A Randomized, Double-blinded Clinical Trial in Cardiac Surgical Patients.
    Anesthesiology, 2015, Volume: 122, Issue:5

    Topics: Aged; Analgesics, Opioid; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cough; Double-Blind M

2015
Intraoperative Methadone for the Prevention of Postoperative Pain: A Randomized, Double-blinded Clinical Trial in Cardiac Surgical Patients.
    Anesthesiology, 2015, Volume: 122, Issue:5

    Topics: Aged; Analgesics, Opioid; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cough; Double-Blind M

2015
Intraoperative Methadone for the Prevention of Postoperative Pain: A Randomized, Double-blinded Clinical Trial in Cardiac Surgical Patients.
    Anesthesiology, 2015, Volume: 122, Issue:5

    Topics: Aged; Analgesics, Opioid; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cough; Double-Blind M

2015
Intraoperative Methadone for the Prevention of Postoperative Pain: A Randomized, Double-blinded Clinical Trial in Cardiac Surgical Patients.
    Anesthesiology, 2015, Volume: 122, Issue:5

    Topics: Aged; Analgesics, Opioid; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cough; Double-Blind M

2015
Intraoperative Methadone for the Prevention of Postoperative Pain: A Randomized, Double-blinded Clinical Trial in Cardiac Surgical Patients.
    Anesthesiology, 2015, Volume: 122, Issue:5

    Topics: Aged; Analgesics, Opioid; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cough; Double-Blind M

2015
Intraoperative Methadone for the Prevention of Postoperative Pain: A Randomized, Double-blinded Clinical Trial in Cardiac Surgical Patients.
    Anesthesiology, 2015, Volume: 122, Issue:5

    Topics: Aged; Analgesics, Opioid; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cough; Double-Blind M

2015
Intraoperative Methadone for the Prevention of Postoperative Pain: A Randomized, Double-blinded Clinical Trial in Cardiac Surgical Patients.
    Anesthesiology, 2015, Volume: 122, Issue:5

    Topics: Aged; Analgesics, Opioid; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cough; Double-Blind M

2015
Intraoperative Methadone for the Prevention of Postoperative Pain: A Randomized, Double-blinded Clinical Trial in Cardiac Surgical Patients.
    Anesthesiology, 2015, Volume: 122, Issue:5

    Topics: Aged; Analgesics, Opioid; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cough; Double-Blind M

2015
Intraoperative Methadone for the Prevention of Postoperative Pain: A Randomized, Double-blinded Clinical Trial in Cardiac Surgical Patients.
    Anesthesiology, 2015, Volume: 122, Issue:5

    Topics: Aged; Analgesics, Opioid; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cough; Double-Blind M

2015
Intraoperative Methadone for the Prevention of Postoperative Pain: A Randomized, Double-blinded Clinical Trial in Cardiac Surgical Patients.
    Anesthesiology, 2015, Volume: 122, Issue:5

    Topics: Aged; Analgesics, Opioid; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cough; Double-Blind M

2015
Intraoperative Methadone for the Prevention of Postoperative Pain: A Randomized, Double-blinded Clinical Trial in Cardiac Surgical Patients.
    Anesthesiology, 2015, Volume: 122, Issue:5

    Topics: Aged; Analgesics, Opioid; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cough; Double-Blind M

2015
Intraoperative Methadone for the Prevention of Postoperative Pain: A Randomized, Double-blinded Clinical Trial in Cardiac Surgical Patients.
    Anesthesiology, 2015, Volume: 122, Issue:5

    Topics: Aged; Analgesics, Opioid; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cough; Double-Blind M

2015
Intraoperative Methadone for the Prevention of Postoperative Pain: A Randomized, Double-blinded Clinical Trial in Cardiac Surgical Patients.
    Anesthesiology, 2015, Volume: 122, Issue:5

    Topics: Aged; Analgesics, Opioid; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cough; Double-Blind M

2015
Intraoperative Methadone for the Prevention of Postoperative Pain: A Randomized, Double-blinded Clinical Trial in Cardiac Surgical Patients.
    Anesthesiology, 2015, Volume: 122, Issue:5

    Topics: Aged; Analgesics, Opioid; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cough; Double-Blind M

2015
Intraoperative Methadone for the Prevention of Postoperative Pain: A Randomized, Double-blinded Clinical Trial in Cardiac Surgical Patients.
    Anesthesiology, 2015, Volume: 122, Issue:5

    Topics: Aged; Analgesics, Opioid; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cough; Double-Blind M

2015
Intraoperative Methadone for the Prevention of Postoperative Pain: A Randomized, Double-blinded Clinical Trial in Cardiac Surgical Patients.
    Anesthesiology, 2015, Volume: 122, Issue:5

    Topics: Aged; Analgesics, Opioid; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cough; Double-Blind M

2015
Intraoperative Methadone for the Prevention of Postoperative Pain: A Randomized, Double-blinded Clinical Trial in Cardiac Surgical Patients.
    Anesthesiology, 2015, Volume: 122, Issue:5

    Topics: Aged; Analgesics, Opioid; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cough; Double-Blind M

2015
Intraoperative Methadone for the Prevention of Postoperative Pain: A Randomized, Double-blinded Clinical Trial in Cardiac Surgical Patients.
    Anesthesiology, 2015, Volume: 122, Issue:5

    Topics: Aged; Analgesics, Opioid; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cough; Double-Blind M

2015
Intraoperative Methadone for the Prevention of Postoperative Pain: A Randomized, Double-blinded Clinical Trial in Cardiac Surgical Patients.
    Anesthesiology, 2015, Volume: 122, Issue:5

    Topics: Aged; Analgesics, Opioid; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cough; Double-Blind M

2015
Butorphanol suppresses fentanyl-induced cough during general anesthesia induction: A randomized, double-blinded, placebo-controlled clinical trial.
    Medicine, 2016, Volume: 95, Issue:26

    Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Antitussive Agents; Butorphanol; Cough; Double

2016
Swallowing action immediately before intravenous fentanyl at induction of anesthesia prevents fentanyl-induced coughing: a randomized controlled study.
    Journal of anesthesia, 2017, Volume: 31, Issue:2

    Topics: Administration, Intravenous; Adult; Analgesics, Opioid; Cough; Deglutition; Elective Surgical Proced

2017
Fentanyl-induced cough does not depend on injection speed: a randomized study.
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:8

    Topics: Cough; Female; Fentanyl; Humans; Injections, Intravenous; Male; Middle Aged; Time Factors

2008
[Intravenous injection rate and site of fentanyl affect the incidence and onset time of fentanyl-induced cough].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2009, Volume: 29, Issue:2

    Topics: Adjuvants, Anesthesia; Adolescent; Adult; Aged; Cough; Female; Fentanyl; Humans; Injections, Intrave

2009
[Incidence and onset time of fentanyl-induced cough depends on the dose of IV fentanyl].
    Masui. The Japanese journal of anesthesiology, 2009, Volume: 58, Issue:8

    Topics: Adolescent; Adult; Anesthesia, General; Anesthetics, Intravenous; Cough; Dose-Response Relationship,

2009
Effects of different priming doses of propofol on fentanyl-induced cough during anesthesia induction: a preliminary randomized controlled study.
    Upsala journal of medical sciences, 2010, Volume: 115, Issue:2

    Topics: Adjuvants, Anesthesia; Adult; Anesthetics, Intravenous; Cough; Dose-Response Relationship, Drug; Fem

2010
The effect of pre-emptive use of minimal dose fentanyl on fentanyl-induced coughing.
    Anaesthesia, 2010, Volume: 65, Issue:1

    Topics: Adolescent; Adult; Aged; Anesthetics, Intravenous; Blood Pressure; Cough; Dose-Response Relationship

2010
A huffing manoeuvre, immediately before induction of anaesthesia, prevents fentanyl-induced coughing: a prospective, randomized, and controlled study.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Adolescent; Adult; Anesthetics, Intravenous; Cough; Exhalation; Female; Fentanyl; Humans; Injections

2010
The frequency of fentanyl-induced cough in children and its effects on tracheal intubation.
    Journal of clinical anesthesia, 2010, Volume: 22, Issue:1

    Topics: Adolescent; Child; Child, Preschool; Cough; Dose-Response Relationship, Drug; Double-Blind Method; F

2010
Effects of fentanyl infusion on tracheal intubation and emergence agitation in preschool children anaesthetized with sevoflurane.
    British journal of anaesthesia, 2010, Volume: 105, Issue:3

    Topics: Adjuvants, Anesthesia; Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthetics, Inhalation;

2010
[Effect of optimizing anesthetic injecting sequence during induction on fentanyl-induced coughing].
    Zhonghua yi xue za zhi, 2010, Apr-06, Volume: 90, Issue:13

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Cough; Female; Fentanyl; Humans; Male; Middle Aged; Yo

2010
Effect of intravenous dezocine on fentanyl-induced cough during general anesthesia induction: a double-blinded, prospective, randomized, controlled trial.
    Journal of anesthesia, 2011, Volume: 25, Issue:6

    Topics: Anesthesia, General; Anesthetics, Intravenous; Bridged Bicyclo Compounds, Heterocyclic; Cough; Doubl

2011
Comparison between intraoperative fentanyl and tramadol to improve quality of emergence.
    Journal of neurosurgical anesthesiology, 2012, Volume: 24, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthesia Recovery Period; Blood Pr

2012
Comparison between intraoperative fentanyl and tramadol to improve quality of emergence.
    Journal of neurosurgical anesthesiology, 2012, Volume: 24, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthesia Recovery Period; Blood Pr

2012
Comparison between intraoperative fentanyl and tramadol to improve quality of emergence.
    Journal of neurosurgical anesthesiology, 2012, Volume: 24, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthesia Recovery Period; Blood Pr

2012
Comparison between intraoperative fentanyl and tramadol to improve quality of emergence.
    Journal of neurosurgical anesthesiology, 2012, Volume: 24, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthesia Recovery Period; Blood Pr

2012
Dose-dependent attenuation by fentanyl on cough during emergence from general anesthesia.
    Acta anaesthesiologica Scandinavica, 2011, Volume: 55, Issue:10

    Topics: Adult; Airway Extubation; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation;

2011
Effects of a priming dose of fentanyl during anaesthesia on the incidence and severity of fentanyl-induced cough in current, former and non-smokers.
    The Journal of international medical research, 2011, Volume: 39, Issue:6

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Cough; Dose-Response Relatio

2011
Dexmedetomidine reduces the incidence of fentanyl-induced cough: a double-blind, randomized, and placebo-controlled study.
    Upsala journal of medical sciences, 2012, Volume: 117, Issue:1

    Topics: Adjuvants, Anesthesia; Adrenergic alpha-2 Receptor Agonists; Adult; Cough; Dexmedetomidine; Double-B

2012
Premedication with intravenous dexmedetomidine-midazolam suppresses fentanyl-induced cough.
    Irish journal of medical science, 2012, Volume: 181, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthetics, Intravenous; Cough; Dexmedetomidine; Drug Combinations; Female

2012
Effects of different priming doses of fentanyl on fentanyl-induced cough: a double-blind, randomized, controlled study.
    Pharmacological reports : PR, 2012, Volume: 64, Issue:2

    Topics: Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Cough; Dose-Response Relationship, Drug;

2012
Priming dose of intravenous rocuronium suppresses fentanyl-induced coughing.
    Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists, 2012, Volume: 50, Issue:4

    Topics: Adult; Aged; Analgesics, Opioid; Androstanols; Cough; Female; Fentanyl; Humans; Injections, Intraven

2012
Salbutamol, beclomethasone or sodium chromoglycate suppress coughing induced by iv fentanyl.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2003, Volume: 50, Issue:3

    Topics: Adolescent; Adult; Albuterol; Beclomethasone; Cough; Cromolyn Sodium; Female; Fentanyl; Histamine Re

2003
Intravenous lidocaine suppresses fentanyl-induced coughing: a double-blind, prospective, randomized placebo-controlled study.
    Anesthesia and analgesia, 2004, Volume: 99, Issue:6

    Topics: Adult; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Cough; Double-Blind Method; Fema

2004
Intravenous lidocaine 0.5 mg.kg-1 effectively suppresses fentanyl-induced cough.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2005, Volume: 52, Issue:2

    Topics: Adolescent; Adult; Anesthesia; Anesthetics, Intravenous; Anesthetics, Local; Cough; Double-Blind Met

2005
Comparative study of intubating conditions at the first minute with suxamethonium, rocuronium and different priming techniques of rocuronium.
    European journal of anaesthesiology, 2005, Volume: 22, Issue:4

    Topics: Adjuvants, Anesthesia; Adult; Aged; Androstanols; Anesthesia, General; Anesthetics, Intravenous; Atr

2005
Prolonged injection time and light smoking decrease the incidence of fentanyl-induced cough.
    Anesthesia and analgesia, 2005, Volume: 101, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Intravenous; Anesthetics, Intravenous; Cough

2005
Comparative evaluation of different doses of propofol preceded by fentanyl on intubating conditions and pressor response during tracheal intubation without muscle relaxants.
    Paediatric anaesthesia, 2006, Volume: 16, Issue:4

    Topics: Anesthesia, General; Anesthetics, Intravenous; Blood Pressure; Child; Child, Preschool; Cough; Doubl

2006
Fentanyl reduces desflurane-induced airway irritability following thiopental administration in children.
    Acta anaesthesiologica Scandinavica, 2006, Volume: 50, Issue:9

    Topics: Analgesics, Opioid; Anesthesia, General; Anesthetics, Inhalation; Apnea; Blood Pressure; Child; Chil

2006
The influence of premedication and smoking.
    Middle East journal of anaesthesiology, 2006, Volume: 18, Issue:5

    Topics: Anesthetics, Intravenous; Anti-Anxiety Agents; Cough; Elective Surgical Procedures; Fentanyl; Humans

2006
Premedication with intravenous low-dose ketamine suppresses fentanyl-induced cough.
    Journal of clinical anesthesia, 2007, Volume: 19, Issue:1

    Topics: Adult; Anesthesia, General; Anesthetics, Dissociative; Anesthetics, Intravenous; Cough; Double-Blind

2007
Pre-medication with intravenous clonidine suppresses fentanyl-induced cough.
    Acta anaesthesiologica Scandinavica, 2007, Volume: 51, Issue:7

    Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Blood Pre

2007
Effect of total intravenous anaesthesia and balanced anaesthesia on the frequency of coughing during emergence from the anaesthesia.
    British journal of anaesthesia, 2007, Volume: 99, Issue:4

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inh

2007
Effect of total intravenous anaesthesia and balanced anaesthesia on the frequency of coughing during emergence from the anaesthesia.
    British journal of anaesthesia, 2007, Volume: 99, Issue:4

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inh

2007
Effect of total intravenous anaesthesia and balanced anaesthesia on the frequency of coughing during emergence from the anaesthesia.
    British journal of anaesthesia, 2007, Volume: 99, Issue:4

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inh

2007
Effect of total intravenous anaesthesia and balanced anaesthesia on the frequency of coughing during emergence from the anaesthesia.
    British journal of anaesthesia, 2007, Volume: 99, Issue:4

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inh

2007
Effect of total intravenous anaesthesia and balanced anaesthesia on the frequency of coughing during emergence from the anaesthesia.
    British journal of anaesthesia, 2007, Volume: 99, Issue:4

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inh

2007
Effect of total intravenous anaesthesia and balanced anaesthesia on the frequency of coughing during emergence from the anaesthesia.
    British journal of anaesthesia, 2007, Volume: 99, Issue:4

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inh

2007
Effect of total intravenous anaesthesia and balanced anaesthesia on the frequency of coughing during emergence from the anaesthesia.
    British journal of anaesthesia, 2007, Volume: 99, Issue:4

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inh

2007
Effect of total intravenous anaesthesia and balanced anaesthesia on the frequency of coughing during emergence from the anaesthesia.
    British journal of anaesthesia, 2007, Volume: 99, Issue:4

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inh

2007
Effect of total intravenous anaesthesia and balanced anaesthesia on the frequency of coughing during emergence from the anaesthesia.
    British journal of anaesthesia, 2007, Volume: 99, Issue:4

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inh

2007
The effect of dilution and prolonged injection time on fentanyl-induced coughing.
    Anaesthesia, 2007, Volume: 62, Issue:9

    Topics: Adult; Anesthetics, Intravenous; Cough; Dose-Response Relationship, Drug; Female; Fentanyl; Humans;

2007
Intravenous dexamethasone pretreatment reduces fentanyl-induced cough.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2007, Volume: 106, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Cough; Dexamethasone; Female;

2007
Comparison of the incidence and severity of cough induced by sufentanil and fentanyl: a prospective, randomised, double-blind study.
    Anaesthesia, 2007, Volume: 62, Issue:12

    Topics: Adult; Analgesics, Opioid; Cough; Double-Blind Method; Female; Fentanyl; Humans; Intraoperative Comp

2007
Rapid tracheal intubation with atracurium: the timing principle.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1994, Volume: 41, Issue:8

    Topics: Adult; Anesthesia, Intravenous; Atracurium; Blood Pressure; Cough; Female; Fentanyl; Flushing; Heart

1994
Motor signs of wakefulness during general anaesthesia with propofol, isoflurane and flunitrazepam/fentanyl and midlatency auditory evoked potentials.
    Anaesthesia, 1994, Volume: 49, Issue:6

    Topics: Adult; Anesthesia, Epidural; Anesthesia, General; Cough; Evoked Potentials, Auditory; Female; Fentan

1994
Comparison of propofol versus thiopentone with midazolam or lidocaine to facilitate laryngeal mask insertion.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:6

    Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Cough; Drug Costs; Elective Surgical Procedures

1996
Terbutaline inhalation suppresses fentanyl-induced coughing.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:12

    Topics: Administration, Inhalation; Adolescent; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonist

1996
The effects of epidural fentanyl on hemodynamic responses during emergence from isoflurane anesthesia and tracheal extubation: a comparison with intravenous fentanyl.
    Anesthesia and analgesia, 1997, Volume: 85, Issue:2

    Topics: Adjuvants, Anesthesia; Adult; Anesthesia Recovery Period; Anesthesia, Epidural; Anesthesia, Inhalati

1997
Postoperative analgesia with epidural bupivacaine and low-dose fentanyl--a comparison of two concentrations.
    Acta anaesthesiologica Scandinavica, 1998, Volume: 42, Issue:7

    Topics: Aged; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Buprenorphine; Colon

1998
Adrenaline markedly improves thoracic epidural analgesia produced by a low-dose infusion of bupivacaine, fentanyl and adrenaline after major surgery. A randomised, double-blind, cross-over study with and without adrenaline.
    Acta anaesthesiologica Scandinavica, 1998, Volume: 42, Issue:8

    Topics: Adrenergic alpha-Agonists; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bupivacaine;

1998
[Our negative experience with meperidine for the prevention of coughing during cataract surgery].
    Revista espanola de anestesiologia y reanimacion, 1999, Volume: 46, Issue:3

    Topics: Antitussive Agents; Cataract Extraction; Cough; Double-Blind Method; Fentanyl; Humans; Intraocular P

1999
Emergence from anesthesia in the prone versus supine position in patients undergoing lumbar surgery.
    Anesthesiology, 2000, Volume: 93, Issue:4

    Topics: Androstanols; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Inhalation; Anestheti

2000
Intravenous opioids reduce airway irritation during induction of anaesthesia with desflurane in adults.
    British journal of anaesthesia, 2000, Volume: 85, Issue:3

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Anesthetics, Inhalation; Cough; Desflurane; Female; F

2000
Epidural fentanyl markedly improves thoracic epidural analgesia in a low-dose infusion of bupivacaine, adrenaline and fentanyl. A randomized, double-blind crossover study with and without fentanyl.
    Acta anaesthesiologica Scandinavica, 2001, Volume: 45, Issue:2

    Topics: Analgesics, Opioid; Anesthesia, Epidural; Anesthetics, Local; Bupivacaine; Cough; Cross-Over Studies

2001
Epinephrine markedly improves thoracic epidural analgesia produced by a small-dose infusion of ropivacaine, fentanyl, and epinephrine after major thoracic or abdominal surgery: a randomized, double-blinded crossover study with and without epinephrine.
    Anesthesia and analgesia, 2002, Volume: 94, Issue:6

    Topics: Adjuvants, Anesthesia; Amides; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioi

2002
Antitussive respiratory depressant effects of dextromoramide, fentanyl, morphine, pentazocine, and pethidine during the N2O-O2 anaesthesia in man.
    Annals of clinical research, 1977, Volume: 9, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Antitussive Agents; Atropi

1977
Tussive effect of a fentanyl bolus.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1991, Volume: 38, Issue:3

    Topics: Adult; Analysis of Variance; Anesthesia, Intravenous; Atropine; Blood Pressure; Cough; Double-Blind

1991
Tussive effect of a fentanyl bolus administered through a central venous catheter.
    Anaesthesia, 1990, Volume: 45, Issue:1

    Topics: Catheterization, Central Venous; Catheterization, Peripheral; Cough; Fentanyl; Humans; Male; Middle

1990

Other Studies

27 other studies available for fentanyl and Cough

ArticleYear
Risk Factors for Fentanyl-Induced Cough Following General Anesthesia in Adults: A Retrospective Study from a Single Center in China.
    Medical science monitor : international medical journal of experimental and clinical research, 2021, Jul-13, Volume: 27

    Topics: Adjuvants, Anesthesia; Administration, Intravenous; Adult; Anesthesia, General; Anesthetics, Intrave

2021
Effect of swallowing maneuver on fentanyl-induced coughing.
    Journal of anesthesia, 2017, Volume: 31, Issue:6

    Topics: Analgesics, Opioid; Anesthesia; Cough; Deglutition; Fentanyl; Humans

2017
Effect of swallowing maneuver on fentanyl-induced coughing.
    Journal of anesthesia, 2017, Volume: 31, Issue:6

    Topics: Analgesics, Opioid; Cough; Deglutition; Fentanyl; Humans

2017
Fentanyl-induced cough is a risk factor for postoperative nausea and vomiting.
    British journal of anaesthesia, 2015, Volume: 115, Issue:3

    Topics: Adult; Anesthetics, Intravenous; Causality; Cohort Studies; Comorbidity; Cough; Female; Fentanyl; Hu

2015
The effect of titrated fentanyl on suppressed cough reflex in healthy adult volunteers.
    Anaesthesia, 2016, Volume: 71, Issue:5

    Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Citric Acid; Cough; Dose-Response Relationship, Drug; F

2016
Evidence appraisal of Li CC, Chen SS, Huang CH, et al. Fentanyl-induced cough is a risk factor for postoperative nausea and vomiting. Br J Anaesth. 2015;115(3):444-448.
    AORN journal, 2016, Volume: 103, Issue:1

    Topics: Anesthetics, Intravenous; Cough; Female; Fentanyl; Humans; Postoperative Nausea and Vomiting

2016
Fentanyl-induced cough is a risk factor for postoperative nausea and vomiting.
    British journal of anaesthesia, 2016, Volume: 117, Issue:2

    Topics: Anesthetics, Intravenous; Cough; Fentanyl; Humans; Postoperative Nausea and Vomiting; Risk Factors;

2016
Incidence of fentanyl-induced cough and injection speed.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:9

    Topics: Analgesics, Opioid; Catheterization, Peripheral; Cough; Dose-Response Relationship, Drug; Fentanyl;

2009
The possible mechanism of clonidine to suppress fentanyl-induced coughing.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:9

    Topics: Adrenergic alpha-Agonists; Anesthetics, Intravenous; Clonidine; Cough; Fentanyl; Humans; Muscle Rigi

2009
Guidelines for prevention of fentanyl-induced cough.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:9

    Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Asthma; Cough; Fentanyl; Humans

2009
[Opioid induced cough: Do we know its pathophysiology and can it be eliminated?].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 2010, Volume: 45, Issue:3

    Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Anesthetics, Local; Clonidine; Cough; Fentanyl; Human

2010
[Fentanyl-induced cough].
    Masui. The Japanese journal of anesthesiology, 2010, Volume: 59, Issue:4

    Topics: Anesthetics, Intravenous; Cough; Dose-Response Relationship, Drug; Fentanyl; Humans; Injections, Int

2010
[Cough reflex after intravenous injection of fentanyl].
    Masui. The Japanese journal of anesthesiology, 2010, Volume: 59, Issue:4

    Topics: Anesthetics, Intravenous; Cough; Dose-Response Relationship, Drug; Fentanyl; Humans; Injections, Int

2010
Fentanyl-induced cough.
    Anaesthesia, 2010, Volume: 65, Issue:5

    Topics: Anesthetics, Combined; Anesthetics, Intravenous; Cough; Fentanyl; Humans; Propofol

2010
Minimum alveolar concentration of desflurane with fentanyl for laryngeal mask airway removal in anesthetized children.
    Paediatric anaesthesia, 2012, Volume: 22, Issue:4

    Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Child; Child, Preschool; Cou

2012
Dezocine: a novel drug to prevent fentanyl-induced cough during general anesthesia induction?
    Journal of anesthesia, 2012, Volume: 26, Issue:3

    Topics: Anesthetics, Intravenous; Bridged Bicyclo Compounds, Heterocyclic; Cough; Female; Fentanyl; Humans;

2012
The relationship between postoperative intravenous patient-controlled fentanyl analgesic requirements and severity of liver disease.
    Transplantation proceedings, 2012, Volume: 44, Issue:2

    Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Chi-Square Distribution; Cough; Female; Fentanyl;

2012
Fentanyl-induced coughing and airway hyperresponsiveness.
    Acta anaesthesiologica Sinica, 2002, Volume: 40, Issue:4

    Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Angiotensin-Converting Enzyme Inhibitors; Bronchial Hyp

2002
Does fentanyl-induced cough justify pre-treatment with iv lidocaine 2 mg.kg-1.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2005, Volume: 52, Issue:2

    Topics: Anesthetics, Intravenous; Anesthetics, Local; Bronchodilator Agents; Cough; Ephedrine; Fentanyl; Hum

2005
Identification of independent risk factors for fentanyl-induced cough.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2006, Volume: 53, Issue:8

    Topics: Adult; Age Factors; Anesthesia, Epidural; Anesthetics, Intravenous; Anesthetics, Local; Angiotensin-

2006
The use of patient-controlled epidural fentanyl in elderly patients.
    Anaesthesia, 2007, Volume: 62, Issue:12

    Topics: Abdomen; Adult; Age Factors; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Body Weight; C

2007
A survey of pentobarbital sedation for children undergoing abdominal CT scans after oral contrast medium.
    Paediatric anaesthesia, 1997, Volume: 7, Issue:4

    Topics: Adjuvants, Anesthesia; Administration, Oral; Airway Obstruction; Anesthesiology; Bronchial Spasm; Ch

1997
Trained nurses can provide safe and effective sedation for MRI in pediatric patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2000, Volume: 47, Issue:3

    Topics: Administration, Rectal; Adolescent; Age Factors; Anesthesia, General; Anesthesiology; Anesthetics, I

2000
Explosive coughing after bolus fentanyl injection.
    Anesthesia and analgesia, 2001, Volume: 92, Issue:6

    Topics: Adolescent; Analgesics, Opioid; Cough; Down Syndrome; Fentanyl; Humans; Injections, Intravenous; Mal

2001
Coughing after fentanyl.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1992, Volume: 39, Issue:4

    Topics: Anesthesia, Intravenous; Cough; Fentanyl; Humans; Pseudotumor Cerebri

1992
Tussive effect of fentanyl.
    Anaesthesia, 1990, Volume: 45, Issue:7

    Topics: Anesthesia, Intravenous; Cough; Fentanyl; Humans

1990
Intubation under topical supra-glottic analgesia in unpremedicated and non-fasting patients: amnesic effects of sub-hypnotic doses of diazepam and Innovar.
    Canadian Anaesthetists' Society journal, 1974, Volume: 21, Issue:5

    Topics: Adolescent; Adult; Aged; Amnesia; Analgesia; Cough; Diazepam; Droperidol; Drug Combinations; Female;

1974