cimetidine and Cough
cimetidine has been researched along with Cough in 4 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Actively sensitized guinea-pigs were challenged with aerosol antigen (ovalbumin, OVA) and cough reflex sensitivity to inhaled capsaicin was measured 24 h later." | 3.73 | Attenuating effect of H+K+ATPase inhibitors on airway cough hypersensitivity induced by allergic airway inflammation in guinea-pigs. ( Fujimura, M; Hara, J; Katayama, N; Kita, T; Myou, S; Nakao, S; Nishitsuji, M; Oribe, Y, 2005) |
| "Although gastro-esophageal reflux (GER) is one of the major causes of chronic persistent cough (CPC) in the USA and in Europe, it is a rare cause of CPC in Japan." | 1.29 | [A case of chronic persistent cough caused by gastro-esophageal reflux]. ( Amemiya, T; Fujimura, M; Matsuda, T; Mizuguchi, M; Nishi, K; Ooka, T, 1995) |
Research
Studies (4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Oribe, Y | 1 |
| Fujimura, M | 2 |
| Kita, T | 1 |
| Katayama, N | 1 |
| Nishitsuji, M | 1 |
| Hara, J | 1 |
| Myou, S | 1 |
| Nakao, S | 1 |
| Nosál'ová, G | 1 |
| Strapková, A | 1 |
| Korpás, J | 1 |
| Bolser, DC | 1 |
| DeGennaro, FC | 1 |
| O'Reilly, S | 1 |
| Hey, JA | 1 |
| Chapman, RW | 1 |
| Nishi, K | 1 |
| Amemiya, T | 1 |
| Mizuguchi, M | 1 |
| Ooka, T | 1 |
| Matsuda, T | 1 |
Other Studies
4 other studies available for cimetidine and Cough
| Article | Year |
|---|---|
Attenuating effect of H+K+ATPase inhibitors on airway cough hypersensitivity induced by allergic airway inflammation in guinea-pigs.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Allergens; Animals; Benzimidazoles; Bronchi; Bronchoalveola | 2005 |
[Experimental cough and histamine receptor blockers].
Topics: Animals; Antitussive Agents; Cats; Cimetidine; Clemastine; Cough; Female; Guanidines; Male; Pyrrolid | 1983 |
Pharmacological studies of allergic cough in the guinea pig.
Topics: Administration, Oral; Aerosols; Albuterol; Analysis of Variance; Animals; Antitussive Agents; Capsai | 1995 |
[A case of chronic persistent cough caused by gastro-esophageal reflux].
Topics: Aged; Chronic Disease; Cimetidine; Cough; Female; Gastroesophageal Reflux; Histamine H2 Antagonists; | 1995 |