Page last updated: 2024-10-25

cimetidine and Cough

cimetidine has been researched along with Cough in 4 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.

Research Excerpts

ExcerptRelevanceReference
"Actively sensitized guinea-pigs were challenged with aerosol antigen (ovalbumin, OVA) and cough reflex sensitivity to inhaled capsaicin was measured 24 h later."3.73Attenuating effect of H+K+ATPase inhibitors on airway cough hypersensitivity induced by allergic airway inflammation in guinea-pigs. ( Fujimura, M; Hara, J; Katayama, N; Kita, T; Myou, S; Nakao, S; Nishitsuji, M; Oribe, Y, 2005)
"Although gastro-esophageal reflux (GER) is one of the major causes of chronic persistent cough (CPC) in the USA and in Europe, it is a rare cause of CPC in Japan."1.29[A case of chronic persistent cough caused by gastro-esophageal reflux]. ( Amemiya, T; Fujimura, M; Matsuda, T; Mizuguchi, M; Nishi, K; Ooka, T, 1995)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Oribe, Y1
Fujimura, M2
Kita, T1
Katayama, N1
Nishitsuji, M1
Hara, J1
Myou, S1
Nakao, S1
Nosál'ová, G1
Strapková, A1
Korpás, J1
Bolser, DC1
DeGennaro, FC1
O'Reilly, S1
Hey, JA1
Chapman, RW1
Nishi, K1
Amemiya, T1
Mizuguchi, M1
Ooka, T1
Matsuda, T1

Other Studies

4 other studies available for cimetidine and Cough

ArticleYear
Attenuating effect of H+K+ATPase inhibitors on airway cough hypersensitivity induced by allergic airway inflammation in guinea-pigs.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2005, Volume: 35, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Allergens; Animals; Benzimidazoles; Bronchi; Bronchoalveola

2005
[Experimental cough and histamine receptor blockers].
    Bratislavske lekarske listy, 1983, Volume: 79, Issue:3

    Topics: Animals; Antitussive Agents; Cats; Cimetidine; Clemastine; Cough; Female; Guanidines; Male; Pyrrolid

1983
Pharmacological studies of allergic cough in the guinea pig.
    European journal of pharmacology, 1995, Apr-24, Volume: 277, Issue:2-3

    Topics: Administration, Oral; Aerosols; Albuterol; Analysis of Variance; Animals; Antitussive Agents; Capsai

1995
[A case of chronic persistent cough caused by gastro-esophageal reflux].
    Nihon Kyobu Shikkan Gakkai zasshi, 1995, Volume: 33, Issue:6

    Topics: Aged; Chronic Disease; Cimetidine; Cough; Female; Gastroesophageal Reflux; Histamine H2 Antagonists;

1995