Page last updated: 2024-10-23

bupivacaine and Cough

bupivacaine has been researched along with Cough in 32 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.

Research Excerpts

ExcerptRelevanceReference
" However, there was a significant reduction of postoperative pain in the bupivacaine group as well at rest as coughing."9.14[Efficiency of bupivacaine wound subfasciale infiltration in reduction of postoperative pain after inguinal hernia surgery]. ( Atmani, M; Azendour, H; Belyamani, L; Bensghir, M; Drissi Kamili, N; Elmoqaddem, A; Massou, S; Mounir, K, 2010)
"The aim of this prospective double-blind randomized placebo-controlled study was to investigate the effect of intrapleural bupivacaine on ipsilateral post-thoracotomy shoulder pain in patients receiving thoracic epidural analgesia."9.11Double-blind comparison of intrapleural saline and 0.25% bupivacaine for ipsilateral shoulder pain after thoracotomy in patients receiving thoracic epidural analgesia. ( Akrofi, ME; Kendall, JB; Pennefather, SH; Russell, GN; Scawn, ND, 2005)
"1% bupivacaine to PCEA using buprenorphine and droperidol provides better analgesia on coughing after gynecological surgery."9.11Addition of 0.1% bupivacaine to buprenorphine and droperidol in patient-controlled epidural analgesia improved postoperative pain scores on coughing after gynecological surgery. ( Hirabayashi, Y; Inoue, S; Kawakami, T; Mitsuhata, H; Seo, N; Shimohata, K, 2005)
" However, there was a significant reduction of postoperative pain in the bupivacaine group as well at rest as coughing."5.14[Efficiency of bupivacaine wound subfasciale infiltration in reduction of postoperative pain after inguinal hernia surgery]. ( Atmani, M; Azendour, H; Belyamani, L; Bensghir, M; Drissi Kamili, N; Elmoqaddem, A; Massou, S; Mounir, K, 2010)
"The aim of this prospective double-blind randomized placebo-controlled study was to investigate the effect of intrapleural bupivacaine on ipsilateral post-thoracotomy shoulder pain in patients receiving thoracic epidural analgesia."5.11Double-blind comparison of intrapleural saline and 0.25% bupivacaine for ipsilateral shoulder pain after thoracotomy in patients receiving thoracic epidural analgesia. ( Akrofi, ME; Kendall, JB; Pennefather, SH; Russell, GN; Scawn, ND, 2005)
"1% bupivacaine to PCEA using buprenorphine and droperidol provides better analgesia on coughing after gynecological surgery."5.11Addition of 0.1% bupivacaine to buprenorphine and droperidol in patient-controlled epidural analgesia improved postoperative pain scores on coughing after gynecological surgery. ( Hirabayashi, Y; Inoue, S; Kawakami, T; Mitsuhata, H; Seo, N; Shimohata, K, 2005)
" Patients with only mild pain when coughing during thoracic epidural infusion of about 10 ml per hour of bupivacaine 1 mg x ml(-1), fentanyl 2 microg x ml(-1), and adrenaline 2 microg x ml(-1) were included."5.09Epidural fentanyl markedly improves thoracic epidural analgesia in a low-dose infusion of bupivacaine, adrenaline and fentanyl. A randomized, double-blind crossover study with and without fentanyl. ( Breivik, H; Niemi, G, 2001)
"In 11 patients scheduled for open midline laparotomy, cough pressure (PCOUGH), a proxy for strength, was measured with a rectal balloon at three moments: before the procedure, at baseline; before surgery, under epidural bupivacaine to T6; and postoperatively, under epidural bupivacaine to the same analgesic level (T6)."4.31Effects of midline laparotomy on cough strength: a prospective study measuring cough pressure. ( Aguilera, LG; Duran, X; Escolano, F; Gallart, L; Ramos, I, 2023)
" Four percent bupivacaine produced arrhythmias in 5 of 10 cats in two groups and apnea in 4 of 6 cats."3.67Duration and toxicity of bupivacaine for topical anesthesia of the airway in the cat. ( Ford, DJ; Raj, PP; Singh, P; Watters, C, 1984)
"The effects of inhalation of 100 breaths of bupivacaine hydrochloride (5 percent solution in saline) on the cough reflex, the Breuer-Hering inflation, reflex, and the duration of apnea and bronchoconstriction produced by histamine aerosol were studied in nine anesthetized dogs."3.65Inhibition of respiratory reflexes by local anesthetic aerosols in dogs and rabbits. ( Boushey, HA; Dain, DS; Gold, WM, 1975)
"Diclofenac was needed by six patients receiving diamorphine in saline and one receiving diamorphine in bupivacaine (P < 0."2.67Epidural diamorphine infusions with and without 0.167% bupivacaine for post-operative analgesia. ( Alexander, JI; Bambridge, AD; Black, AM; Lowson, SM, 1994)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199010 (31.25)18.7374
1990's12 (37.50)18.2507
2000's6 (18.75)29.6817
2010's1 (3.13)24.3611
2020's3 (9.38)2.80

Authors

AuthorsStudies
Çevikkalp, E1
Narmanlı, M1
Özgüç, H1
Ocakoğlu, G1
Zengin, EN1
Zengin, M1
Yiğit, H1
Sazak, H1
Şekerci, S1
Alagöz, A1
Aguilera, LG1
Gallart, L1
Ramos, I1
Duran, X1
Escolano, F1
Mounir, K1
Bensghir, M1
Elmoqaddem, A1
Massou, S1
Belyamani, L1
Atmani, M1
Azendour, H1
Drissi Kamili, N1
Pennefather, SH1
Akrofi, ME1
Kendall, JB1
Russell, GN1
Scawn, ND1
Inoue, S1
Mitsuhata, H1
Kawakami, T1
Shimohata, K1
Hirabayashi, Y1
Seo, N1
Suzuki, M1
Kinoshita, T1
Kikutani, T1
Yokoyama, K1
Inagi, T1
Sugimoto, K1
Haraguchi, S1
Hisayoshi, T1
Shimada, Y1
Bhatnagar, S1
Mishra, S1
Madhurima, S1
Gurjar, M1
Mondal, AS1
Ford, DJ1
Singh, P1
Watters, C1
Raj, PP1
Roberge, RJ1
Morgenstern, MJ1
Osborn, H1
Møiniche, S1
Bülow, S1
Hesselfeldt, P1
Hestbaek, A1
Kehlet, H4
Joris, J1
Thiry, E1
Paris, P1
Weerts, J1
Lamy, M1
Erichsen, CJ1
Vibits, H1
Dahl, JB3
Lowson, SM1
Alexander, JI1
Black, AM1
Bambridge, AD1
Bartholdy, J1
Sperling, K1
Ibsen, M1
Eliasen, K1
Mogensen, T1
Dierking, GW1
Ostergaard, E1
Ostergård, HT1
Sjöström, S1
Bläss, J1
Niemi, G2
Breivik, H2
Callesen, T1
Schouenborg, L1
Nielsen, D1
Guldager, H1
Peleg, R1
Binyamin, L1
Thomson, NC1
Dain, DS1
Boushey, HA1
Gold, WM1
Cross, BA1
Guz, A2
Jain, SK2
Archer, S1
Stevens, J1
Reynolds, F2
Eng, J1
Sabanathan, S1
Rosenberg, J1
Hansen, BL1
Hjortsø, NC1
Kastrissios, H1
Mogg, GA1
Triggs, EJ1
Higbie, JW1
Brown, RC1
Turton, CW1
Kato, H1
Menon, AS1
Chen, FJ1
Slutsky, AS1
Koenig, SB1
Snyder, RW1
Kay, J1
Addison, NV1
Brear, FA1
Budd, K1
Whittaker, M1
Trenchard, D1
Noble, MI1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Paragastric Lesser Omentum Neural Block to Prevent Visceral Pain After Laparoscopic Sleeve Gastrectomy: A Randomized Clinical Trial Protocol.[NCT05353426]145 participants (Actual)Interventional2021-08-13Completed
Effects of Calot's Triangle Block for Postoperative Analgesia in Patients Undergoing Laparoscopic Cholecystectomy: a Prospective, Randomized, Double-blind, Controlled, Clinical Trial[NCT02300480]Phase 4140 participants (Anticipated)Interventional2014-12-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

19 trials available for bupivacaine and Cough

ArticleYear
Bilateral 4-quadrant laparoscopic-assisted transversus abdominis plane block reduces early postoperative pain after laparoscopic cholecystectomy: A prospective, single-blind, randomized study.
    Saudi medical journal, 2023, Volume: 44, Issue:2

    Topics: Abdominal Muscles; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Cholecystectomy, Laparoscopi

2023
Comparison of the effects of one-level and bi-level pre-incisional erector spinae plane block on postoperative acute pain in video-assisted thoracoscopic surgery; a prospective, randomized, double-blind trial.
    BMC anesthesiology, 2023, 08-11, Volume: 23, Issue:1

    Topics: Acute Pain; Analgesia, Patient-Controlled; Analgesics, Opioid; Bupivacaine; Cough; Drug-Related Side

2023
[Efficiency of bupivacaine wound subfasciale infiltration in reduction of postoperative pain after inguinal hernia surgery].
    Annales francaises d'anesthesie et de reanimation, 2010, Volume: 29, Issue:4

    Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Body Temperature; Bupivacaine; Chronic Disease; Cough

2010
Double-blind comparison of intrapleural saline and 0.25% bupivacaine for ipsilateral shoulder pain after thoracotomy in patients receiving thoracic epidural analgesia.
    British journal of anaesthesia, 2005, Volume: 94, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthetics, Local; Bupivacaine; Cough; Double-

2005
Addition of 0.1% bupivacaine to buprenorphine and droperidol in patient-controlled epidural analgesia improved postoperative pain scores on coughing after gynecological surgery.
    Journal of clinical anesthesia, 2005, Volume: 17, Issue:3

    Topics: Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Bupivacaine; Buprenorphine; Central Nervo

2005
Determining the plasma concentration of ketamine that enhances epidural bupivacaine-and-morphine-induced analgesia.
    Anesthesia and analgesia, 2005, Volume: 101, Issue:3

    Topics: Adult; Aged; Analgesics, Opioid; Anesthesia, Epidural; Anesthetics, Dissociative; Anesthetics, Local

2005
Clonidine as an analgesic adjuvant to continuous paravertebral bupivacaine for post-thoracotomy pain.
    Anaesthesia and intensive care, 2006, Volume: 34, Issue:5

    Topics: Adrenergic alpha-Agonists; Adult; Aged; Anesthetics, Local; Blood Pressure; Bupivacaine; Clonidine;

2006
Pain after laparoscopic cholecystectomy: characteristics and effect of intraperitoneal bupivacaine.
    Anesthesia and analgesia, 1995, Volume: 81, Issue:2

    Topics: Abdominal Muscles; Analgesics; Anesthesia, Local; Bupivacaine; Cholecystectomy, Laparoscopic; Cough;

1995
Pain after laparoscopic cholecystectomy: characteristics and effect of intraperitoneal bupivacaine.
    Anesthesia and analgesia, 1995, Volume: 81, Issue:2

    Topics: Abdominal Muscles; Analgesics; Anesthesia, Local; Bupivacaine; Cholecystectomy, Laparoscopic; Cough;

1995
Pain after laparoscopic cholecystectomy: characteristics and effect of intraperitoneal bupivacaine.
    Anesthesia and analgesia, 1995, Volume: 81, Issue:2

    Topics: Abdominal Muscles; Analgesics; Anesthesia, Local; Bupivacaine; Cholecystectomy, Laparoscopic; Cough;

1995
Pain after laparoscopic cholecystectomy: characteristics and effect of intraperitoneal bupivacaine.
    Anesthesia and analgesia, 1995, Volume: 81, Issue:2

    Topics: Abdominal Muscles; Analgesics; Anesthesia, Local; Bupivacaine; Cholecystectomy, Laparoscopic; Cough;

1995
Wound infiltration with ropivacaine and bupivacaine for pain after inguinal herniotomy.
    Acta anaesthesiologica Scandinavica, 1995, Volume: 39, Issue:1

    Topics: Adolescent; Adult; Aged; Amides; Analgesics; Anesthetics, Local; Bupivacaine; Cough; Double-Blind Me

1995
Epidural diamorphine infusions with and without 0.167% bupivacaine for post-operative analgesia.
    European journal of anaesthesiology, 1994, Volume: 11, Issue:5

    Topics: Abdomen; Adult; Age Factors; Aged; Analgesia, Epidural; Bupivacaine; Cough; Diclofenac; Drug Combina

1994
Preoperative infiltration of the surgical area enhances postoperative analgesia of a combined low-dose epidural bupivacaine and morphine regimen after upper abdominal surgery.
    Acta anaesthesiologica Scandinavica, 1994, Volume: 38, Issue:3

    Topics: Abdomen; Adult; Aged; Analgesia; Analgesia, Epidural; Bupivacaine; Cough; Dermatologic Surgical Proc

1994
The effects of wound infiltration with bupivacaine versus saline on postoperative pain and opioid requirements after herniorrhaphy.
    Acta anaesthesiologica Scandinavica, 1994, Volume: 38, Issue:3

    Topics: Adult; Aged; Analgesia; Anesthesia, Intravenous; Bupivacaine; Cough; Double-Blind Method; Hernia, In

1994
Postoperative analgesia with epidural bupivacaine and low-dose fentanyl--a comparison of two concentrations.
    Acta anaesthesiologica Scandinavica, 1998, Volume: 42, Issue:7

    Topics: Aged; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Buprenorphine; Colon

1998
Adrenaline markedly improves thoracic epidural analgesia produced by a low-dose infusion of bupivacaine, fentanyl and adrenaline after major surgery. A randomised, double-blind, cross-over study with and without adrenaline.
    Acta anaesthesiologica Scandinavica, 1998, Volume: 42, Issue:8

    Topics: Adrenergic alpha-Agonists; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bupivacaine;

1998
Combined epidural-spinal opioid-free anaesthesia and analgesia for hysterectomy.
    British journal of anaesthesia, 1999, Volume: 82, Issue:6

    Topics: Adult; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, Inhalation; Anesthesia, Spinal; Anesthe

1999
Epidural fentanyl markedly improves thoracic epidural analgesia in a low-dose infusion of bupivacaine, adrenaline and fentanyl. A randomized, double-blind crossover study with and without fentanyl.
    Acta anaesthesiologica Scandinavica, 2001, Volume: 45, Issue:2

    Topics: Analgesics, Opioid; Anesthesia, Epidural; Anesthetics, Local; Bupivacaine; Cough; Cross-Over Studies

2001
Continuous extrapleural intercostal nerve block and post-thoracotomy pulmonary complications.
    Scandinavian journal of thoracic and cardiovascular surgery, 1992, Volume: 26, Issue:3

    Topics: Analgesia; Bupivacaine; Cough; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Interc

1992
Differential analgesic effects of low-dose epidural morphine and morphine-bupivacaine at rest and during mobilization after major abdominal surgery.
    Anesthesia and analgesia, 1992, Volume: 74, Issue:3

    Topics: Abdomen; Abdominal Pain; Aged; Analgesia, Epidural; Bupivacaine; Cough; Dose-Response Relationship,

1992
Interpleural bupivacaine infusion compared with intravenous pethidine infusion after cholecystectomy.
    Anaesthesia and intensive care, 1991, Volume: 19, Issue:4

    Topics: Adult; Bupivacaine; Carbon Dioxide; Cholecystectomy; Cough; Female; Flatulence; Forced Expiratory Vo

1991

Other Studies

13 other studies available for bupivacaine and Cough

ArticleYear
Effects of midline laparotomy on cough strength: a prospective study measuring cough pressure.
    Minerva anestesiologica, 2023, Volume: 89, Issue:12

    Topics: Bupivacaine; Cough; Hand Strength; Humans; Laparotomy; Pain, Postoperative; Prospective Studies

2023
Duration and toxicity of bupivacaine for topical anesthesia of the airway in the cat.
    Anesthesia and analgesia, 1984, Volume: 63, Issue:11

    Topics: Anesthesia, Local; Animals; Apnea; Arrhythmias, Cardiac; Bupivacaine; Cats; Cough; Female; Lidocaine

1984
Cough fracture of the ribs.
    The American journal of emergency medicine, 1984, Volume: 2, Issue:6

    Topics: Age Factors; Aged; Bupivacaine; Cough; Female; Humans; Male; Radiography; Rib Fractures; Sex Factors

1984
Convalescence and hospital stay after colonic surgery with balanced analgesia, early oral feeding, and enforced mobilisation.
    The European journal of surgery = Acta chirurgica, 1995, Volume: 161, Issue:4

    Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Epidural; Bupivacaine; Colectomy; Convales

1995
Practice tips. Treating persistent cough. Try a nebulized mixture of lidocaine and bupivacaine.
    Canadian family physician Medecin de famille canadien, 2002, Volume: 48

    Topics: Administration, Inhalation; Anesthetics, Local; Bupivacaine; Chronic Disease; Cough; Humans; Lidocai

2002
The effect of different pharmacological agents on respiratory reflexes in normal and asthmatic subjects.
    Clinical science (London, England : 1979), 1979, Volume: 56, Issue:3

    Topics: Adolescent; Adult; Aerosols; Asthma; Bupivacaine; Cough; Histamine; Humans; Methacholine Compounds;

1979
Inhibition of respiratory reflexes by local anesthetic aerosols in dogs and rabbits.
    Journal of applied physiology, 1975, Volume: 38, Issue:6

    Topics: Aerosols; Airway Resistance; Anesthesia, Local; Animals; Apnea; Bronchi; Bupivacaine; Constriction;

1975
The effect of anaesthesia of the airway in dog and man: a study of respiratory reflexes, sensations and lung mechanics.
    Clinical science and molecular medicine, 1976, Volume: 50, Issue:6

    Topics: Aerosols; Airway Resistance; Anesthetics, Local; Animals; Bupivacaine; Cough; Dogs; Humans; Kinetics

1976
Cough and angiotensin converting enzyme inhibition.
    British medical journal (Clinical research ed.), 1988, Jun-18, Volume: 296, Issue:6638

    Topics: Aerosols; Aged; Bupivacaine; Captopril; Cough; Humans; Male

1988
Contribution of pulmonary receptors to the heart rate response to acute hypoxemia in rabbits.
    Circulation, 1988, Volume: 78, Issue:5 Pt 1

    Topics: Acute Disease; Afferent Pathways; Animals; Bupivacaine; Cough; Female; Heart Rate; Hypoxia; Lung; Ma

1988
Respiratory distress after a Nadbath block.
    Ophthalmology, 1988, Volume: 95, Issue:9

    Topics: Aged; Bupivacaine; Cough; Deglutition Disorders; Facial Nerve; Female; Hoarseness; Humans; Lidocaine

1988
Epidural analgesia following cholecystectomy.
    The British journal of surgery, 1974, Volume: 61, Issue:10

    Topics: Analgesia; Anesthesia, Epidural; Blood Pressure; Bupivacaine; Catheterization; Cholecystectomy; Coug

1974
The effect of local anaesthesia of the airway on respiratory reflexes in the rabbit.
    Clinical science, 1973, Volume: 44, Issue:6

    Topics: Aerosols; Anesthesia, Local; Animals; Biguanides; Bronchi; Bupivacaine; Constriction; Cough; Electri

1973