bupivacaine and Cough
bupivacaine has been researched along with Cough in 32 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, there was a significant reduction of postoperative pain in the bupivacaine group as well at rest as coughing." | 9.14 | [Efficiency of bupivacaine wound subfasciale infiltration in reduction of postoperative pain after inguinal hernia surgery]. ( Atmani, M; Azendour, H; Belyamani, L; Bensghir, M; Drissi Kamili, N; Elmoqaddem, A; Massou, S; Mounir, K, 2010) |
| "The aim of this prospective double-blind randomized placebo-controlled study was to investigate the effect of intrapleural bupivacaine on ipsilateral post-thoracotomy shoulder pain in patients receiving thoracic epidural analgesia." | 9.11 | Double-blind comparison of intrapleural saline and 0.25% bupivacaine for ipsilateral shoulder pain after thoracotomy in patients receiving thoracic epidural analgesia. ( Akrofi, ME; Kendall, JB; Pennefather, SH; Russell, GN; Scawn, ND, 2005) |
| "1% bupivacaine to PCEA using buprenorphine and droperidol provides better analgesia on coughing after gynecological surgery." | 9.11 | Addition of 0.1% bupivacaine to buprenorphine and droperidol in patient-controlled epidural analgesia improved postoperative pain scores on coughing after gynecological surgery. ( Hirabayashi, Y; Inoue, S; Kawakami, T; Mitsuhata, H; Seo, N; Shimohata, K, 2005) |
| " However, there was a significant reduction of postoperative pain in the bupivacaine group as well at rest as coughing." | 5.14 | [Efficiency of bupivacaine wound subfasciale infiltration in reduction of postoperative pain after inguinal hernia surgery]. ( Atmani, M; Azendour, H; Belyamani, L; Bensghir, M; Drissi Kamili, N; Elmoqaddem, A; Massou, S; Mounir, K, 2010) |
| "The aim of this prospective double-blind randomized placebo-controlled study was to investigate the effect of intrapleural bupivacaine on ipsilateral post-thoracotomy shoulder pain in patients receiving thoracic epidural analgesia." | 5.11 | Double-blind comparison of intrapleural saline and 0.25% bupivacaine for ipsilateral shoulder pain after thoracotomy in patients receiving thoracic epidural analgesia. ( Akrofi, ME; Kendall, JB; Pennefather, SH; Russell, GN; Scawn, ND, 2005) |
| "1% bupivacaine to PCEA using buprenorphine and droperidol provides better analgesia on coughing after gynecological surgery." | 5.11 | Addition of 0.1% bupivacaine to buprenorphine and droperidol in patient-controlled epidural analgesia improved postoperative pain scores on coughing after gynecological surgery. ( Hirabayashi, Y; Inoue, S; Kawakami, T; Mitsuhata, H; Seo, N; Shimohata, K, 2005) |
| " Patients with only mild pain when coughing during thoracic epidural infusion of about 10 ml per hour of bupivacaine 1 mg x ml(-1), fentanyl 2 microg x ml(-1), and adrenaline 2 microg x ml(-1) were included." | 5.09 | Epidural fentanyl markedly improves thoracic epidural analgesia in a low-dose infusion of bupivacaine, adrenaline and fentanyl. A randomized, double-blind crossover study with and without fentanyl. ( Breivik, H; Niemi, G, 2001) |
| "In 11 patients scheduled for open midline laparotomy, cough pressure (PCOUGH), a proxy for strength, was measured with a rectal balloon at three moments: before the procedure, at baseline; before surgery, under epidural bupivacaine to T6; and postoperatively, under epidural bupivacaine to the same analgesic level (T6)." | 4.31 | Effects of midline laparotomy on cough strength: a prospective study measuring cough pressure. ( Aguilera, LG; Duran, X; Escolano, F; Gallart, L; Ramos, I, 2023) |
| " Four percent bupivacaine produced arrhythmias in 5 of 10 cats in two groups and apnea in 4 of 6 cats." | 3.67 | Duration and toxicity of bupivacaine for topical anesthesia of the airway in the cat. ( Ford, DJ; Raj, PP; Singh, P; Watters, C, 1984) |
| "The effects of inhalation of 100 breaths of bupivacaine hydrochloride (5 percent solution in saline) on the cough reflex, the Breuer-Hering inflation, reflex, and the duration of apnea and bronchoconstriction produced by histamine aerosol were studied in nine anesthetized dogs." | 3.65 | Inhibition of respiratory reflexes by local anesthetic aerosols in dogs and rabbits. ( Boushey, HA; Dain, DS; Gold, WM, 1975) |
| "Diclofenac was needed by six patients receiving diamorphine in saline and one receiving diamorphine in bupivacaine (P < 0." | 2.67 | Epidural diamorphine infusions with and without 0.167% bupivacaine for post-operative analgesia. ( Alexander, JI; Bambridge, AD; Black, AM; Lowson, SM, 1994) |
Research
Studies (32)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (31.25) | 18.7374 |
| 1990's | 12 (37.50) | 18.2507 |
| 2000's | 6 (18.75) | 29.6817 |
| 2010's | 1 (3.13) | 24.3611 |
| 2020's | 3 (9.38) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Çevikkalp, E | 1 |
| Narmanlı, M | 1 |
| Özgüç, H | 1 |
| Ocakoğlu, G | 1 |
| Zengin, EN | 1 |
| Zengin, M | 1 |
| Yiğit, H | 1 |
| Sazak, H | 1 |
| Şekerci, S | 1 |
| Alagöz, A | 1 |
| Aguilera, LG | 1 |
| Gallart, L | 1 |
| Ramos, I | 1 |
| Duran, X | 1 |
| Escolano, F | 1 |
| Mounir, K | 1 |
| Bensghir, M | 1 |
| Elmoqaddem, A | 1 |
| Massou, S | 1 |
| Belyamani, L | 1 |
| Atmani, M | 1 |
| Azendour, H | 1 |
| Drissi Kamili, N | 1 |
| Pennefather, SH | 1 |
| Akrofi, ME | 1 |
| Kendall, JB | 1 |
| Russell, GN | 1 |
| Scawn, ND | 1 |
| Inoue, S | 1 |
| Mitsuhata, H | 1 |
| Kawakami, T | 1 |
| Shimohata, K | 1 |
| Hirabayashi, Y | 1 |
| Seo, N | 1 |
| Suzuki, M | 1 |
| Kinoshita, T | 1 |
| Kikutani, T | 1 |
| Yokoyama, K | 1 |
| Inagi, T | 1 |
| Sugimoto, K | 1 |
| Haraguchi, S | 1 |
| Hisayoshi, T | 1 |
| Shimada, Y | 1 |
| Bhatnagar, S | 1 |
| Mishra, S | 1 |
| Madhurima, S | 1 |
| Gurjar, M | 1 |
| Mondal, AS | 1 |
| Ford, DJ | 1 |
| Singh, P | 1 |
| Watters, C | 1 |
| Raj, PP | 1 |
| Roberge, RJ | 1 |
| Morgenstern, MJ | 1 |
| Osborn, H | 1 |
| Møiniche, S | 1 |
| Bülow, S | 1 |
| Hesselfeldt, P | 1 |
| Hestbaek, A | 1 |
| Kehlet, H | 4 |
| Joris, J | 1 |
| Thiry, E | 1 |
| Paris, P | 1 |
| Weerts, J | 1 |
| Lamy, M | 1 |
| Erichsen, CJ | 1 |
| Vibits, H | 1 |
| Dahl, JB | 3 |
| Lowson, SM | 1 |
| Alexander, JI | 1 |
| Black, AM | 1 |
| Bambridge, AD | 1 |
| Bartholdy, J | 1 |
| Sperling, K | 1 |
| Ibsen, M | 1 |
| Eliasen, K | 1 |
| Mogensen, T | 1 |
| Dierking, GW | 1 |
| Ostergaard, E | 1 |
| Ostergård, HT | 1 |
| Sjöström, S | 1 |
| Bläss, J | 1 |
| Niemi, G | 2 |
| Breivik, H | 2 |
| Callesen, T | 1 |
| Schouenborg, L | 1 |
| Nielsen, D | 1 |
| Guldager, H | 1 |
| Peleg, R | 1 |
| Binyamin, L | 1 |
| Thomson, NC | 1 |
| Dain, DS | 1 |
| Boushey, HA | 1 |
| Gold, WM | 1 |
| Cross, BA | 1 |
| Guz, A | 2 |
| Jain, SK | 2 |
| Archer, S | 1 |
| Stevens, J | 1 |
| Reynolds, F | 2 |
| Eng, J | 1 |
| Sabanathan, S | 1 |
| Rosenberg, J | 1 |
| Hansen, BL | 1 |
| Hjortsø, NC | 1 |
| Kastrissios, H | 1 |
| Mogg, GA | 1 |
| Triggs, EJ | 1 |
| Higbie, JW | 1 |
| Brown, RC | 1 |
| Turton, CW | 1 |
| Kato, H | 1 |
| Menon, AS | 1 |
| Chen, FJ | 1 |
| Slutsky, AS | 1 |
| Koenig, SB | 1 |
| Snyder, RW | 1 |
| Kay, J | 1 |
| Addison, NV | 1 |
| Brear, FA | 1 |
| Budd, K | 1 |
| Whittaker, M | 1 |
| Trenchard, D | 1 |
| Noble, MI | 1 |
Clinical Trials (2)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Paragastric Lesser Omentum Neural Block to Prevent Visceral Pain After Laparoscopic Sleeve Gastrectomy: A Randomized Clinical Trial Protocol.[NCT05353426] | 145 participants (Actual) | Interventional | 2021-08-13 | Completed | |||
| Effects of Calot's Triangle Block for Postoperative Analgesia in Patients Undergoing Laparoscopic Cholecystectomy: a Prospective, Randomized, Double-blind, Controlled, Clinical Trial[NCT02300480] | Phase 4 | 140 participants (Anticipated) | Interventional | 2014-12-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Trials
19 trials available for bupivacaine and Cough
| Article | Year |
|---|---|
Bilateral 4-quadrant laparoscopic-assisted transversus abdominis plane block reduces early postoperative pain after laparoscopic cholecystectomy: A prospective, single-blind, randomized study.
Topics: Abdominal Muscles; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Cholecystectomy, Laparoscopi | 2023 |
Comparison of the effects of one-level and bi-level pre-incisional erector spinae plane block on postoperative acute pain in video-assisted thoracoscopic surgery; a prospective, randomized, double-blind trial.
Topics: Acute Pain; Analgesia, Patient-Controlled; Analgesics, Opioid; Bupivacaine; Cough; Drug-Related Side | 2023 |
[Efficiency of bupivacaine wound subfasciale infiltration in reduction of postoperative pain after inguinal hernia surgery].
Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Body Temperature; Bupivacaine; Chronic Disease; Cough | 2010 |
Double-blind comparison of intrapleural saline and 0.25% bupivacaine for ipsilateral shoulder pain after thoracotomy in patients receiving thoracic epidural analgesia.
Topics: Adult; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthetics, Local; Bupivacaine; Cough; Double- | 2005 |
Addition of 0.1% bupivacaine to buprenorphine and droperidol in patient-controlled epidural analgesia improved postoperative pain scores on coughing after gynecological surgery.
Topics: Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Bupivacaine; Buprenorphine; Central Nervo | 2005 |
Determining the plasma concentration of ketamine that enhances epidural bupivacaine-and-morphine-induced analgesia.
Topics: Adult; Aged; Analgesics, Opioid; Anesthesia, Epidural; Anesthetics, Dissociative; Anesthetics, Local | 2005 |
Clonidine as an analgesic adjuvant to continuous paravertebral bupivacaine for post-thoracotomy pain.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Anesthetics, Local; Blood Pressure; Bupivacaine; Clonidine; | 2006 |
Pain after laparoscopic cholecystectomy: characteristics and effect of intraperitoneal bupivacaine.
Topics: Abdominal Muscles; Analgesics; Anesthesia, Local; Bupivacaine; Cholecystectomy, Laparoscopic; Cough; | 1995 |
Pain after laparoscopic cholecystectomy: characteristics and effect of intraperitoneal bupivacaine.
Topics: Abdominal Muscles; Analgesics; Anesthesia, Local; Bupivacaine; Cholecystectomy, Laparoscopic; Cough; | 1995 |
Pain after laparoscopic cholecystectomy: characteristics and effect of intraperitoneal bupivacaine.
Topics: Abdominal Muscles; Analgesics; Anesthesia, Local; Bupivacaine; Cholecystectomy, Laparoscopic; Cough; | 1995 |
Pain after laparoscopic cholecystectomy: characteristics and effect of intraperitoneal bupivacaine.
Topics: Abdominal Muscles; Analgesics; Anesthesia, Local; Bupivacaine; Cholecystectomy, Laparoscopic; Cough; | 1995 |
Wound infiltration with ropivacaine and bupivacaine for pain after inguinal herniotomy.
Topics: Adolescent; Adult; Aged; Amides; Analgesics; Anesthetics, Local; Bupivacaine; Cough; Double-Blind Me | 1995 |
Epidural diamorphine infusions with and without 0.167% bupivacaine for post-operative analgesia.
Topics: Abdomen; Adult; Age Factors; Aged; Analgesia, Epidural; Bupivacaine; Cough; Diclofenac; Drug Combina | 1994 |
Preoperative infiltration of the surgical area enhances postoperative analgesia of a combined low-dose epidural bupivacaine and morphine regimen after upper abdominal surgery.
Topics: Abdomen; Adult; Aged; Analgesia; Analgesia, Epidural; Bupivacaine; Cough; Dermatologic Surgical Proc | 1994 |
The effects of wound infiltration with bupivacaine versus saline on postoperative pain and opioid requirements after herniorrhaphy.
Topics: Adult; Aged; Analgesia; Anesthesia, Intravenous; Bupivacaine; Cough; Double-Blind Method; Hernia, In | 1994 |
Postoperative analgesia with epidural bupivacaine and low-dose fentanyl--a comparison of two concentrations.
Topics: Aged; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Buprenorphine; Colon | 1998 |
Adrenaline markedly improves thoracic epidural analgesia produced by a low-dose infusion of bupivacaine, fentanyl and adrenaline after major surgery. A randomised, double-blind, cross-over study with and without adrenaline.
Topics: Adrenergic alpha-Agonists; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; | 1998 |
Combined epidural-spinal opioid-free anaesthesia and analgesia for hysterectomy.
Topics: Adult; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, Inhalation; Anesthesia, Spinal; Anesthe | 1999 |
Epidural fentanyl markedly improves thoracic epidural analgesia in a low-dose infusion of bupivacaine, adrenaline and fentanyl. A randomized, double-blind crossover study with and without fentanyl.
Topics: Analgesics, Opioid; Anesthesia, Epidural; Anesthetics, Local; Bupivacaine; Cough; Cross-Over Studies | 2001 |
Continuous extrapleural intercostal nerve block and post-thoracotomy pulmonary complications.
Topics: Analgesia; Bupivacaine; Cough; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Interc | 1992 |
Differential analgesic effects of low-dose epidural morphine and morphine-bupivacaine at rest and during mobilization after major abdominal surgery.
Topics: Abdomen; Abdominal Pain; Aged; Analgesia, Epidural; Bupivacaine; Cough; Dose-Response Relationship, | 1992 |
Interpleural bupivacaine infusion compared with intravenous pethidine infusion after cholecystectomy.
Topics: Adult; Bupivacaine; Carbon Dioxide; Cholecystectomy; Cough; Female; Flatulence; Forced Expiratory Vo | 1991 |
Other Studies
13 other studies available for bupivacaine and Cough
| Article | Year |
|---|---|
Effects of midline laparotomy on cough strength: a prospective study measuring cough pressure.
Topics: Bupivacaine; Cough; Hand Strength; Humans; Laparotomy; Pain, Postoperative; Prospective Studies | 2023 |
Duration and toxicity of bupivacaine for topical anesthesia of the airway in the cat.
Topics: Anesthesia, Local; Animals; Apnea; Arrhythmias, Cardiac; Bupivacaine; Cats; Cough; Female; Lidocaine | 1984 |
Cough fracture of the ribs.
Topics: Age Factors; Aged; Bupivacaine; Cough; Female; Humans; Male; Radiography; Rib Fractures; Sex Factors | 1984 |
Convalescence and hospital stay after colonic surgery with balanced analgesia, early oral feeding, and enforced mobilisation.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Epidural; Bupivacaine; Colectomy; Convales | 1995 |
Practice tips. Treating persistent cough. Try a nebulized mixture of lidocaine and bupivacaine.
Topics: Administration, Inhalation; Anesthetics, Local; Bupivacaine; Chronic Disease; Cough; Humans; Lidocai | 2002 |
The effect of different pharmacological agents on respiratory reflexes in normal and asthmatic subjects.
Topics: Adolescent; Adult; Aerosols; Asthma; Bupivacaine; Cough; Histamine; Humans; Methacholine Compounds; | 1979 |
Inhibition of respiratory reflexes by local anesthetic aerosols in dogs and rabbits.
Topics: Aerosols; Airway Resistance; Anesthesia, Local; Animals; Apnea; Bronchi; Bupivacaine; Constriction; | 1975 |
The effect of anaesthesia of the airway in dog and man: a study of respiratory reflexes, sensations and lung mechanics.
Topics: Aerosols; Airway Resistance; Anesthetics, Local; Animals; Bupivacaine; Cough; Dogs; Humans; Kinetics | 1976 |
Cough and angiotensin converting enzyme inhibition.
Topics: Aerosols; Aged; Bupivacaine; Captopril; Cough; Humans; Male | 1988 |
Contribution of pulmonary receptors to the heart rate response to acute hypoxemia in rabbits.
Topics: Acute Disease; Afferent Pathways; Animals; Bupivacaine; Cough; Female; Heart Rate; Hypoxia; Lung; Ma | 1988 |
Respiratory distress after a Nadbath block.
Topics: Aged; Bupivacaine; Cough; Deglutition Disorders; Facial Nerve; Female; Hoarseness; Humans; Lidocaine | 1988 |
Epidural analgesia following cholecystectomy.
Topics: Analgesia; Anesthesia, Epidural; Blood Pressure; Bupivacaine; Catheterization; Cholecystectomy; Coug | 1974 |
The effect of local anaesthesia of the airway on respiratory reflexes in the rabbit.
Topics: Aerosols; Anesthesia, Local; Animals; Biguanides; Bronchi; Bupivacaine; Constriction; Cough; Electri | 1973 |