azathioprine has been researched along with Gout in 30 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Gout: Metabolic disorder characterized by recurrent acute arthritis, hyperuricemia and deposition of sodium urate in and around the joints, sometimes with formation of URIC ACID calculi.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To describe the use of azathioprine or other immunosuppressive therapies as a pegloticase adjunct to prevent pegloticase immunogenicity when treating gout." | 3.85 | Pegloticase failure and a possible solution: Immunosuppression to prevent intolerance and inefficacy in patients with gout. ( Berhanu, AA; Keenan, RT; Krasnokutsky, S; Pillinger, MH, 2017) |
| "To evaluate the frequency and the pathogenesis of hyperuricemia and gout during cyclosporine therapy, we studied renal-transplant recipients who were treated with either cyclosporine and prednisone (n = 129) or azathioprine and prednisone (n = 168)." | 3.67 | Cyclosporine-induced hyperuricemia and gout. ( Fox, IH; Lin, HY; McQuillan, MA; Palella, TD; Rocher, LL; Schmaltz, S, 1989) |
| "Similarity of the morphological picture of gouty nephropathy and primary glomerulonephritides in which purine antagonists turned out to be effective, a positive effect of azathioprine (Az) and 6-mercaptopurine (MP) on purine metabolism, and changes in immunity indices revealed in gout (hyperproduction of immunoglobulins and circulating immune complexes) necessitates the use of antimetabolites in combined therapy of gout patients with proteinuric and latent types of nephropathy." | 3.67 | [Substantiation and effectiveness of the use of purine antagonists in gouty nephropathy]. ( Diadyk, AI; Nikolenko, IuI; Shpilevaia, NI; Siniachenko, OV; Vasilenko, IV, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (63.33) | 18.7374 |
| 1990's | 5 (16.67) | 18.2507 |
| 2000's | 2 (6.67) | 29.6817 |
| 2010's | 3 (10.00) | 24.3611 |
| 2020's | 1 (3.33) | 2.80 |
| Authors | Studies |
|---|---|
| Keenan, RT | 2 |
| Botson, JK | 1 |
| Masri, KR | 1 |
| Padnick-Silver, L | 1 |
| LaMoreaux, B | 1 |
| Albert, JA | 1 |
| Pillinger, MH | 2 |
| Weiler, S | 1 |
| Aellig, N | 1 |
| Fauchère, I | 1 |
| Jetter, A | 1 |
| Corti, N | 1 |
| Berhanu, AA | 1 |
| Krasnokutsky, S | 1 |
| Lam, MY | 1 |
| Feller, ER | 1 |
| Lonks, JR | 1 |
| Shah, SA | 1 |
| Kaczmorski, S | 1 |
| Doares, W | 1 |
| Winfrey, S | 1 |
| Al-Geizawi, S | 1 |
| Farney, A | 1 |
| Rogers, J | 1 |
| Stratta, R | 1 |
| Edwards, NL | 1 |
| Sorensen, LB | 2 |
| Benke, PJ | 1 |
| Ben Hmida, M | 1 |
| Hachicha, J | 1 |
| Bahloul, Z | 1 |
| Kaddour, N | 1 |
| Kharrat, M | 1 |
| Jarraya, F | 1 |
| Jarraya, A | 1 |
| Schumacher, HR | 1 |
| Perez-Ruiz, F | 1 |
| Alonso-Ruiz, A | 1 |
| Calabozo, M | 1 |
| Duruelo, J | 1 |
| Westberg, NG | 1 |
| Rosén, E | 1 |
| Waldenström, J | 1 |
| Glogner, P | 1 |
| Heni, N | 1 |
| Müller, MM | 1 |
| Kaiser, E | 1 |
| Delaney, V | 1 |
| Sumrani, N | 1 |
| Daskalakis, P | 1 |
| Hong, JH | 1 |
| Sommer, BG | 1 |
| Lin, HY | 1 |
| Rocher, LL | 1 |
| McQuillan, MA | 1 |
| Schmaltz, S | 1 |
| Palella, TD | 1 |
| Fox, IH | 1 |
| Tiller, DJ | 1 |
| Hall, BM | 1 |
| Horvarth, JS | 1 |
| Duggin, GG | 1 |
| Thompson, JF | 1 |
| Sheil, AG | 1 |
| Gores, PF | 1 |
| Fryd, DS | 1 |
| Sutherland, DE | 1 |
| Najarian, JS | 1 |
| Simmons, RL | 1 |
| West, C | 1 |
| Carpenter, BJ | 1 |
| Hakala, TR | 1 |
| Siniachenko, OV | 1 |
| Diadyk, AI | 1 |
| Nikolenko, IuI | 1 |
| Vasilenko, IV | 1 |
| Shpilevaia, NI | 1 |
| Bach, JF | 2 |
| Bach, MA | 2 |
| Dardenne, M | 2 |
| Huskisson, EC | 1 |
| Klein, G | 2 |
| Fellner, S | 1 |
| Fellner, R | 1 |
| Kölle, G | 1 |
| Stoeber, E | 1 |
| Schöntag, W | 1 |
| Kelley, WN | 1 |
| Greene, ML | 2 |
| Rosenbloom, FM | 1 |
| Henderson, JF | 1 |
| Seegmiller, JE | 2 |
| Glueck, CJ | 1 |
| Fujimoto, WY | 1 |
| Nyhan, WL | 1 |
| Sweetman, L | 1 |
| Carpenter, DG | 1 |
| Carter, CH | 1 |
| Hoefnagel, D | 1 |
3 reviews available for azathioprine and Gout
| Article | Year |
|---|---|
The effect of immunomodulators on the efficacy and tolerability of pegloticase: a systematic review.
Topics: Azathioprine; Gout; Gout Suppressants; Humans; Immunologic Factors; Polyethylene Glycols; Urate Oxid | 2021 |
Crystal deposition disease.
Topics: Antirheumatic Agents; Azathioprine; Chondrocalcinosis; Colchicine; Cyclosporine; Gout; Gout Suppress | 1997 |
Hypoxanthine-guanine phosphoribosyltransferase deficiency in gout.
Topics: Adenine; Adolescent; Adult; Allopurinol; Azathioprine; Child; Child, Preschool; Female; Gout; Humans | 1969 |
3 trials available for azathioprine and Gout
| Article | Year |
|---|---|
Hyperuricemia and gout in renal allograft recipients.
Topics: Adult; Azathioprine; Cyclosporine; Gout; Humans; Kidney Transplantation; Risk Factors; Transplantati | 1992 |
Hyperuricemia after renal transplantation.
Topics: Antilymphocyte Serum; Azathioprine; Clinical Trials as Topic; Cyclosporins; Drug Therapy, Combinatio | 1988 |
[Indomethacin in rheumatic diseases with special reference to ophthalmologic studies].
Topics: Allopurinol; Arthritis, Rheumatoid; Azathioprine; Blood Cells; Capsules; Clinical Trials as Topic; E | 1972 |
24 other studies available for azathioprine and Gout
| Article | Year |
|---|---|
Treatment of gout in a renal transplant patient leading to severe thrombocytopenia.
Topics: Aged; Allopurinol; Azathioprine; Diagnosis, Differential; Female; Gout; Gout Suppressants; Humans; I | 2014 |
Pegloticase failure and a possible solution: Immunosuppression to prevent intolerance and inefficacy in patients with gout.
Topics: Azathioprine; Drug Therapy, Combination; Gout; Gout Suppressants; Humans; Immunosuppressive Agents; | 2017 |
Inflammatory bowel disease potpourri: a vignette-based discussion.
Topics: Adult; Allopurinol; Azathioprine; Clostridioides difficile; Colitis, Ulcerative; Crohn Disease; Drug | 2009 |
Gout and transplantation: new treatment option-same old drug interaction.
Topics: Aged; Azathioprine; Drug Interactions; Febuxostat; Gout; Gout Suppressants; Graft Rejection; Humans; | 2011 |
Case 9: initiation of urate-lowering therapy for advanced gout complicated by chronic renal insufficiency.
Topics: Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Contraindications; Drug Interact | 2006 |
Biochemical evidence for a distinct type of primary gout.
Topics: Adolescent; Allopurinol; Azathioprine; Carbon; Carbon Isotopes; Enzymes; Glycine; Gout; Humans; Hypo | 1967 |
Cyclosporine-induced hyperuricemia and gout in renal transplants.
Topics: Adult; Allopurinol; Azathioprine; Cyclosporine; Drug Interactions; Gout; Gout Suppressants; Humans; | 1995 |
Treatment of gout after transplantation.
Topics: Allopurinol; Azathioprine; Cyclosporine; Diuretics; Drug Interactions; Furosemide; Gout; Gout Suppre | 1998 |
Recessive X-linked hyperuricemia with gout and renal damage, normal activity of hypoxanthine phosphoribosyltransferase and resistance to azaguanine.
Topics: Adenine Phosphoribosyltransferase; Adolescent; Adult; Azaguanine; Azathioprine; Erythrocytes; Female | 1979 |
[Pancytopenia following combination treatment with allopurinol and azathioprine].
Topics: Allopurinol; Anemia, Aplastic; Azathioprine; Drug Interactions; Drug Therapy, Combination; Gout; Hum | 1976 |
[Regulation of purine metabolism and its modification by drugs].
Topics: Allopurinol; Antimetabolites; Azathioprine; Benzofurans; Chemical Phenomena; Chemistry; Erythrocytes | 1975 |
Cyclosporine-induced hyperuricemia and gout.
Topics: Allopurinol; Azathioprine; Cyclosporins; Drug Interactions; Gout; Humans; Transplantation, Homologou | 1990 |
Cyclosporine-induced hyperuricemia and gout.
Topics: Adult; Arthritis, Gouty; Azathioprine; Creatinine; Cyclosporins; Drug Therapy, Combination; Female; | 1989 |
Gout and hyperuricaemia in patients on cyclosporin and diuretics.
Topics: Adult; Antilymphocyte Serum; Azathioprine; Cyclosporins; Diuretics; Female; Gout; Humans; Kidney Dis | 1985 |
The incidence of gout in renal transplant recipients.
Topics: Azathioprine; Cyclosporins; Diuretics; Female; Gout; Humans; Kidney Transplantation; Male; Retrospec | 1987 |
[Substantiation and effectiveness of the use of purine antagonists in gouty nephropathy].
Topics: Adult; Azathioprine; Drug Therapy, Combination; Gout; Humans; Kidney Diseases; Mercaptopurine; Middl | 1987 |
The use of certain immunosuppressive drugs in the clinical study of gout.
Topics: Azathioprine; Erythrocytes; Gout; Humans; Immune Adherence Reaction; Lymphocyte Culture Test, Mixed; | 1974 |
Recent drugs and the rheumatic diseases.
Topics: Acetaminophen; Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non- | 1974 |
[Immunosuppressive agents in the basic therapy of visceral forms of rheumatoid arthritis in children].
Topics: Adolescent; Adrenal Cortex Hormones; Amyloidosis; Arthritis, Juvenile; Arthritis, Rheumatoid; Azathi | 1972 |
[Determination of active metabolites of immunosuppressive agents in the serum. Application to azathioprine].
Topics: Anemia, Aplastic; Azathioprine; Gout; Hepatitis; Histocompatibility Testing; Humans; Immune Adherenc | 1972 |
[Long-term studies on indomethacin in rheumatology with special reference to its use in combination with azathioprine].
Topics: Administration, Oral; Arthritis; Arthritis, Rheumatoid; Azathioprine; Chronic Disease; Drug Combinat | 1971 |
Suppression of the shunt pathway in primary gout by azathioprine.
Topics: Adenine Nucleotides; Azathioprine; Blood; Enzyme Repression; Glycine; Gout; Guanine Nucleotides; Hum | 1966 |
Benign symmetric lipomatosis (Launois-Bensaude adenolipomatosis) with gout and hyperlipoproteinemia.
Topics: Adult; Azathioprine; Blood Protein Electrophoresis; Carbon Isotopes; Female; Glucose Tolerance Test; | 1970 |
Effects of azathiprine in a disorder of uric acid metabolism and cerebral function.
Topics: Adult; Azathioprine; Blood Platelets; Brain Diseases; Child; Gout; Hematocrit; Hemoglobinometry; Hum | 1968 |