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amiodarone and Pain

amiodarone has been researched along with Pain in 7 studies

Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"Amiodarone was found to produce a statistically significant decrease in heat, cold, and mechanical hyperalgesia in a rat model of neuropathic pain after intraperitoneal injection."7.72Amiodarone decreases heat, cold, and mechanical hyperalgesia in a rat model of neuropathic pain. ( Datta, S; Glusman, S; Torres, M; Waghray, T, 2004)
"The medical records, including radiographic imaging, pathology and operative reports, of 2 postpubertal boys who had sterile epididymitis after prolonged therapy with amiodarone were reviewed."7.70Amiodarone induced epididymitis in children. ( Diamond, DA; Hutcheson, J; Peters, CA, 1998)
"Amiodarone was found to produce a statistically significant decrease in heat, cold, and mechanical hyperalgesia in a rat model of neuropathic pain after intraperitoneal injection."3.72Amiodarone decreases heat, cold, and mechanical hyperalgesia in a rat model of neuropathic pain. ( Datta, S; Glusman, S; Torres, M; Waghray, T, 2004)
"The medical records, including radiographic imaging, pathology and operative reports, of 2 postpubertal boys who had sterile epididymitis after prolonged therapy with amiodarone were reviewed."3.70Amiodarone induced epididymitis in children. ( Diamond, DA; Hutcheson, J; Peters, CA, 1998)
"Fifty-three patients with hypertrophic cardiomyopathy who had serious arrhythmias (45 patients), refractory chest pain (5 patients) or a high risk of sudden death (3 patients) received amiodarone for 6 to 96 months (median 18) after completion of a loading and an initial maintenance period."3.67Amiodarone for long-term management of patients with hypertrophic cardiomyopathy. ( Goodwin, JF; Harris, L; Kleinebenne, A; Krikler, DM; McKenna, WJ; Oakley, CM; Rowland, E, 1984)
"Rats were treated with amiodarone (20 mg/kg/day) up to 6 weeks and the neurotoxicity was assessed by determining changes in motor coordination, pain-threshold and rectal temperature every week during treatment."3.67Neurotoxicity in rats following subchronic amiodarone treatment. ( Fernando, JC; Ho, IK; Mehendale, HM; Rao, KS, 1986)
" The dosage of amiodarone was reduced from 400 mg/day to 200 mg/day without reduction of mexiletine or disopyramide and the patient's symptoms diminished."1.30A case report of myolysis during high-dose amiodarone therapy for uncontrolled ventricular tachycardia. ( Hotta, N; Itoh, K; Kato, R, 1998)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's2 (28.57)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Sileno, S1
Chirila, RM1
Harris, DM1
Datta, S1
Waghray, T1
Torres, M1
Glusman, S1
McKenna, WJ1
Harris, L1
Rowland, E1
Kleinebenne, A1
Krikler, DM1
Oakley, CM1
Goodwin, JF1
Itoh, K1
Kato, R1
Hotta, N1
Hutcheson, J1
Peters, CA1
Diamond, DA1
Miaskiewicz, SL1
Amico, JA1
Follansbee, WP1
Levey, GS1
Rao, KS1
Fernando, JC1
Ho, IK1
Mehendale, HM1

Reviews

1 review available for amiodarone and Pain

ArticleYear
Use of statins, amiodarone, direct oral anticoagulants and NSAIDs in chronic liver disease: a guide for general clinicians.
    Romanian journal of internal medicine = Revue roumaine de medecine interne, 2020, Dec-01, Volume: 58, Issue:4

    Topics: Administration, Oral; Amiodarone; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; A

2020

Other Studies

6 other studies available for amiodarone and Pain

ArticleYear
Amiodarone decreases heat, cold, and mechanical hyperalgesia in a rat model of neuropathic pain.
    Anesthesia and analgesia, 2004, Volume: 98, Issue:1

    Topics: Amiodarone; Anesthetics, Local; Animals; Cold Temperature; Hot Temperature; Hyperalgesia; Injections

2004
Amiodarone for long-term management of patients with hypertrophic cardiomyopathy.
    The American journal of cardiology, 1984, Oct-01, Volume: 54, Issue:7

    Topics: Adolescent; Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Atrial Fibrillation; Benzofurans; Cardiom

1984
A case report of myolysis during high-dose amiodarone therapy for uncontrolled ventricular tachycardia.
    Japanese circulation journal, 1998, Volume: 62, Issue:4

    Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Cardiomyopathies; Humans; Male; Muscle, Skeletal; Pain; S

1998
Amiodarone induced epididymitis in children.
    The Journal of urology, 1998, Volume: 160, Issue:2

    Topics: Adolescent; Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Child; Death, Sudden, Ca

1998
Amiodarone-associated thyrotoxicosis masquerading as painful thyroiditis.
    Annals of internal medicine, 1987, Volume: 107, Issue:1

    Topics: Amiodarone; Diagnosis, Differential; Humans; Male; Middle Aged; Pain; Thyroiditis, Subacute; Thyroto

1987
Neurotoxicity in rats following subchronic amiodarone treatment.
    Research communications in chemical pathology and pharmacology, 1986, Volume: 52, Issue:2

    Topics: Amiodarone; Animals; Benzofurans; Body Temperature; Body Weight; Drinking Behavior; Feeding Behavior

1986