Page last updated: 2024-11-08

alanine and Bleeding

alanine has been researched along with Bleeding in 11 studies

Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.

Research Excerpts

ExcerptRelevanceReference
" The 2 populations studied were as follows: (1) a cross-sectional study of 703 acute coronary syndrome (ACS) patients with myocardial infarction (MI) and unstable angina, and (2) a prospective study of 924 Caucasian patients from the OPUS (Orbofiban in Patients with Unstable coronary Syndromes)-TIMI-16 trial of the oral GPIIb/IIIa antagonist orbofiban."5.10Genetic variability in the extracellular matrix as a determinant of cardiovascular risk: association of type III collagen COL3A1 polymorphisms with coronary artery disease. ( Fitzgerald, A; Fitzgerald, DJ; Muckian, C; O'Byrne, A; O'Neill, A; Shields, DC, 2002)
" The relevance of circadian dosing time was investigated for chronotherapeutic optimization of SDX-102."1.33Circadian pharmacology of L-alanosine (SDX-102) in mice. ( Carrière, J; Crépin, D; Elliott, G; Guettier, C; Kanekal, S; Lévi, F; Li, XM, 2006)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's0 (0.00)18.2507
2000's10 (90.91)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Muckian, C2
Fitzgerald, A2
O'Neill, A1
O'Byrne, A1
Fitzgerald, DJ3
Shields, DC3
BORRELLI, F1
DELLORUSSO, R1
Li, XM1
Kanekal, S1
Crépin, D1
Guettier, C1
Carrière, J1
Elliott, G1
Lévi, F1
Meyer, M1
Dietzel, H1
Kaetzel, R1
Schmidt, D1
Liebscher, K1
Brennan, SO1
Pruissen, DM1
Rosendaal, FR1
Gorter, JW1
Garcia, AA1
Kappelle, LJ1
Algra, A1
Ulrich, S1
Brand, B1
Speich, R1
Oldenburg, J2
Asmis, L1
Sabatine, MS1
Jang, IK1
Chew, DP1
Bhatt, DL1
Sapp, S1
Topol, EJ1
Neuhaus, T1
Hertfelder, HJ1
Hess, L1
Walger, P1
Vetter, H1
O'Connor, FF1
Cannon, CP2
Braunwald, E1
Fitzgerald, AP1
O'Neill, PA1
Kenny, D1
Moran, B1
Byrne, CE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
In-vivo Thrombus Imaging With 18F-GP1, a Novel Platelet PET Radiotracer[NCT03943966]73 participants (Actual)Interventional2019-11-11Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for alanine and Bleeding

ArticleYear
The use of glycoprotein IIb/IIIa inhibitors in patients with coronary artery disease.
    The American journal of medicine, 2000, Aug-15, Volume: 109, Issue:3

    Topics: Abciximab; Acetates; Acute Disease; Administration, Oral; Alanine; Angioplasty, Balloon, Coronary; A

2000
Increased mortality with oral platelet glycoprotein IIb/IIIa antagonists: a meta-analysis of phase III multicenter randomized trials.
    Circulation, 2001, Jan-16, Volume: 103, Issue:2

    Topics: Administration, Oral; Alanine; Aspirin; Benzamidines; Clinical Trials, Phase III as Topic; Coronary

2001

Trials

3 trials available for alanine and Bleeding

ArticleYear
Genetic variability in the extracellular matrix as a determinant of cardiovascular risk: association of type III collagen COL3A1 polymorphisms with coronary artery disease.
    Blood, 2002, Aug-15, Volume: 100, Issue:4

    Topics: Alanine; Alleles; Angina, Unstable; Collagen; Collagen Type III; Coronary Disease; Cross-Sectional S

2002
Genetic variation in glycoprotein IIb/IIIa (GPIIb/IIIa) as a determinant of the responses to an oral GPIIb/IIIa antagonist in patients with unstable coronary syndromes.
    Blood, 2001, Dec-01, Volume: 98, Issue:12

    Topics: Aged; Alanine; Angina, Unstable; Antigens, Human Platelet; Aspirin; Double-Blind Method; Female; Gen

2001
The contribution of genetic factors to thrombotic and bleeding outcomes in coronary patients randomised to IIb/IIIa antagonists.
    The pharmacogenomics journal, 2002, Volume: 2, Issue:3

    Topics: Alanine; Coronary Disease; Genotype; Glycoproteins; Hemorrhage; Humans; Myocardial Infarction; Myoca

2002

Other Studies

6 other studies available for alanine and Bleeding

ArticleYear
[PLASMA ENZYME BEHAVIOR (ASPARTIC AND ALANINE KETOGLUTARIC TRANSAMINASES) IN HEMORRHAGIC SUBJECTS].
    Rassegna internazionale di clinica e terapia, 1963, Dec-15, Volume: 43

    Topics: Alanine; Alanine Transaminase; Aspartate Aminotransferases; Blood Chemical Analysis; Clinical Enzyme

1963
Circadian pharmacology of L-alanosine (SDX-102) in mice.
    Molecular cancer therapeutics, 2006, Volume: 5, Issue:2

    Topics: Alanine; Animals; Antineoplastic Agents; Body Weight; Bone Marrow; Chronotherapy; Darkness; Gene Exp

2006
Fibrinogen Leipzig II (gamma351Gly-->Ser and gamma82Ala-->Gly): hypodysfibrinogenaemia due to two independent amino acid substitutions within the same polypeptide chain.
    Thrombosis and haemostasis, 2007, Volume: 98, Issue:4

    Topics: Adult; Afibrinogenemia; Alanine; Fibrinogen; Glycine; Haplotypes; Hemorrhage; Heterozygote; Humans;

2007
Haemostatic genetic variants, ABO blood group and bleeding risk during oral anticoagulant treatment after cerebral ischaemia of arterial origin.
    Journal of neurology, 2007, Volume: 254, Issue:12

    Topics: ABO Blood-Group System; Administration, Oral; Aged; Alanine; Anticoagulants; Arteries; Blood Protein

2007
Congenital hypersensitivity to vitamin K antagonists due to FIX propeptide mutation at locus -10: a (not so) rare cause of bleeding under oral anticoagulant therapy in Switzerland.
    Swiss medical weekly, 2008, Feb-23, Volume: 138, Issue:7-8

    Topics: Aged; Alanine; Amino Acid Substitution; Anticoagulants; Coumarins; Drug Hypersensitivity; Factor IX;

2008
[An uncommon cause of severe soft tissue bleeding during phenprocoumon treatment].
    Deutsche medizinische Wochenschrift (1946), 2001, Jun-22, Volume: 126, Issue:25-26

    Topics: Aged; Alanine; Anticoagulants; Aortic Valve; Echocardiography; Factor IX; Heart Valve Prosthesis; He

2001