Page last updated: 2024-08-24

adenosine and Obesity

adenosine has been researched along with Obesity in 71 studies

Research

Studies (71)

TimeframeStudies, this research(%)All Research%
pre-19908 (11.27)18.7374
1990's9 (12.68)18.2507
2000's16 (22.54)29.6817
2010's21 (29.58)24.3611
2020's17 (23.94)2.80

Authors

AuthorsStudies
Arumugam, S; Flavell, RA; Li, B; Li, HB; Li, J; Lu, Q; Mankash, SM; Ouyang, X; Qin, Y; Sun, B1
Blüher, M; Böttcher, Y; Cayir, A; Dahl, MB; Keller, M; Rønningen, T; Tönjes, A; Valderhaug, TG1
Lv, B; Qin, Y; Tian, Z; Xu, Z; Zhang, B1
Friebel, J; Hassanein, A; Jakobs, K; Landmesser, U; Puccini, M; Rauch, C; Rauch, U1
Chen, Z; Dai, G; Fan, W; Ma, D; Mo, W; Pan, J; Wu, G; Zhang, X1
Calkhoven, CF; Zuidhof, HR1
Chang, R; Huang, Z; Li, Y; Tan, S; Zhao, S; Zou, J1
Cai, Y; Chen, X; Li, J; Wen, Z; Yi, B1
Li, DL; Li, Y; Tian, X; Wang, ZY; Zhang, CY1
Donder, E; Karakulak, K; Kaymaz, T; Onalan, E; Onalan, EE; Yakar, B1
Ban, J; Chen, S; Chen, X; Jia, Z; Li, Z; Niu, S; Pan, X; Ren, Q; Yue, L; Zhen, R; Zhu, R1
Li, SM; Ma, LL; Wang, BH; Xie, W; Xu, YQ1
Gao, Y; Ge, W; Liu, J; Sun, Q; Xu, X; Yang, X; Yang, Y; Zhang, J; Zhao, Y1
Morris, A1
Cui, SX; Doviak, H; Epstein, FH; French, BA; Leor, J; Sano, S; Shah, SA; Walsh, K; Wang, Y; Waters, CD1
Griñán-Ferré, C; Izquierdo, V; Pallàs, M; Palomera-Ávalos, V1
Sun, M; Zhang, X1
Han, X; Li, W; Wang, N; Yao, L; Zhang, L; Zhao, Y; Zhou, L1
Acurio, J; Badillo, P; Bravo, P; Escudero, C; Gonzalez, MA; Guevara, K; Oyarzun, C; Salgado, P; San Martin, R1
Caprioli, RM; Kahn, CR; Manier, ML; Orliaguet, L; Reyzer, ML; Soto, M1
Deng, Z; Jiang, S; Li, S; Lu, J; Peng, J; Song, T; Wei, H; Xu, T; Yang, Y1
Agista, AZ; Goto, T; Ikeda, I; Inagawa, Y; Komai, M; Koseki, T; Shirakawa, H1
Chen, J; Du, B1
Alarcón, S; Niechi, I; Quezada, C; Sobrevia, L; Toledo, F1
Belardinelli, L; Bingham, J; Dhalla, AK; Ho, YL; Staehr, PM; Wang, X; Zack, J1
Dahl, JA; Klungland, A1
Cataño-Cañizalez, YG; Cortés-Garcia, JD; Cortez-Espinosa, N; Guzman-Flores, JM; Portales-Perez, DP; Rodríguez-Rivera, JG; Vargas-Morales, JM1
Gutiérrez, J; Leiva, A; Pardo, F; Sáez, T; Salsoso, R; Sanhueza, C; Silva, L; Sobrevia, L1
Cao, Q; Chai, J; Guo, F; Ma, J; Zhang, M; Zhang, Y; Zhao, R; Zhao, W; Zhou, B1
Birnbaum, GD; Birnbaum, I; Birnbaum, Y; Nylander, S; Ye, Y1
Chiarello, DI; Gutierrez, J; Leiva, A; Pardo, F; Salsoso, R; Sobrevia, L; Toledo, F; Villalobos-Labra, R1
Guo, X; Ji, S; Ji, X; Wei, W1
Cerqueira, MD; Iskandrian, AE; Nguyen, P; Staehr, P; Underwood, SR1
Baghdoyan, HA; Lydic, R; Wang, W1
Boegehold, MA; Brock, RW; Frisbee, JC; Hollander, JM; Yu, HG1
Hester, RL; Xiang, L1
Boncompagni, E; Carlucci, F; Cillo, U; Ferrigno, A; Freitas, I; Gringeri, E; Neri, D; Richelmi, P; Rizzo, V; Tabucchi, A; Tommassini, V; Vairetti, M1
Coffey, JP; Hill, JC; Woywodt, A1
Jadhav, AA; Jain, A1
Adluru, G; Chen, L; DiBella, EV; Fluckiger, JU; Jiji, R; Kim, TH; Kuppahally, S; Litwin, SE; Matthews, B; McGann, C; Pack, NA; Priester, T1
Dai, Q; Fu, Y; He, C; Jia, G; Lindahl, T; Pan, T; Yang, Y; Yang, YG; Yi, C; Zhao, X; Zheng, G1
Kantola, I; Knuuti, J; Nuutila, P; Raitakari, OT; Sundell, J; Viikari, J1
Bongardt, S; Burghoff, S; Burkart, V; Eberhard, D; Eckel, J; Flögel, U; Ikels, K; Kern, M; Klöting, N; Schrader, J; Sell, H; Tucci, S1
Graham, TE; Thong, FS1
Huupponen, R; Knuuti, J; Nuutila, P; Raitakari, OT; Sundell, J1
Furlong, KT; Lang, RM; Lodato, JA; Takeuchi, M; Yoshikawa, J1
Farkas, GA; Lee, SD; Nakano, H1
Knuuti, J; Laine, H; Luotolahti, M; Nuutila, P; Sundell, J1
Antic, S; Lazarević, G; Milojkovic, M; Stefanovic, V; Vlahovic, P1
Emeson, RB; Gore, JC; Jacobs, MM; Joers, JM; Kesterson, RA; Singh, M1
Llamas, R1
Fisher, M; Green, A; Newsholme, EA1
Berkich, DA; LaNoue, KF; Linden, J; Luthin, DR; Vannucci, SJ; Woodard, RL1
Arner, P1
Polonsky, KS; Pugh, W; Tang, J; Zhang, H1
Ciaraldi, TP; Hickman, MG; Morales, AJ; Odom-Ford, R; Olefsky, JM; Yen, SS1
Danhof, M; Ijzerman, AP; Langemeijer, MW; Tukker, HE; van Schaick, EA; Zuideveld, KP1
Fukumori, T; Ohkohchi, N; Satomi, S; Tsukamoto, S1
Frühbeck, G; Gómez-Ambrosi, J; Salvador, J1
Bakker, SJ; Gans, RO; Heine, RJ; Teerlink, T; ter Maaten, JC; Westerhoff, HV1
Al Suwaidi, J; Higano, ST; Holmes, DR; Lennon, R; Lerman, A1
Kalliokoski, K; Knuuti, J; Laine, H; Luotolahti, M; Nuutila, P; Raitakari, O; Sundell, J1
Dulloo, AG; Girardier, L; Seydoux, J1
Hreniuk, SP; Kaartinen, JM; LaNoue, KF; Martin, LF; Ohisalo, JJ; Ranta, S1
Klim, CM; LaNoue, KF; Martin, LF; Vannucci, SJ2
Fischer, B; Kather, H; Schlierf, G; Wieland, E; Wirth, A1
Blomstrand, E; Newell, J; Newsholme, EA; Pitcher, J1
Huhtaniemi, IT; Ohisalo, JJ; Ranta, S1
Fischer, B; Kather, H; Schlierf, G; Wieland, E1
Albini, B; Sundick, RS; Wick, G1

Reviews

13 review(s) available for adenosine and Obesity

ArticleYear
Oncogenic and Tumor-Suppressive Functions of the RNA Demethylase FTO.
    Cancer research, 2022, 06-15, Volume: 82, Issue:12

    Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Carcinogenesis; Humans; Neoplasms; Obesity; RNA; RNA, Messenger

2022
Emerging Roles of FTO in Neuropsychiatric Disorders.
    BioMed research international, 2022, Volume: 2022

    Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Brain Diseases; Humans; Mental Disorders; Obesity; RNA, Messenger

2022
Pathophysiology roles for adenosine 2A receptor in obesity and related diseases.
    Obesity reviews : an official journal of the International Association for the Study of Obesity, 2022, Volume: 23, Issue:10

    Topics: Adenosine; Atherosclerosis; Humans; Non-alcoholic Fatty Liver Disease; Obesity; Osteoarthritis; Receptor, Adenosine A2A

2022
Epigenetic regulation of N6-methyladenosine modifications in obesity.
    Journal of diabetes investigation, 2021, Volume: 12, Issue:8

    Topics: Adenosine; Adipogenesis; Animals; Epigenesis, Genetic; Humans; Methylation; Obesity; RNA Processing, Post-Transcriptional

2021
Novel positioning from obesity to cancer: FTO, an m
    Journal of cancer research and clinical oncology, 2019, Volume: 145, Issue:1

    Topics: 3' Untranslated Regions; Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Body Mass Index; Cell Proliferation; Demethylation; Disease Progression; Drug Resistance, Neoplasm; Epigenesis, Genetic; Gene Expression Regulation; Humans; Neoplasm Metastasis; Neoplasms; Obesity; Oncogenes; Polymorphism, Single Nucleotide; Prognosis; Radiation Tolerance

2019
Glioma progression in diabesity.
    Molecular aspects of medicine, 2019, Volume: 66

    Topics: Adenosine; Antineoplastic Agents; Brain Neoplasms; Diabetes Mellitus, Type 2; Disease Progression; Gene Regulatory Networks; Glioma; Humans; Hypoglycemic Agents; Obesity; Risk Factors; Up-Regulation

2019
Dynamic RNA modifications in disease.
    Current opinion in genetics & development, 2014, Volume: 26

    Topics: Adenosine; AlkB Homolog 5, RNA Demethylase; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Diabetes Mellitus, Type 2; Dioxygenases; Humans; Membrane Proteins; Methyltransferases; Mutation; Obesity; Proteins; RNA, Messenger

2014
Molecular implications of adenosine in obesity.
    Molecular aspects of medicine, 2017, Volume: 55

    Topics: Adenosine; Adipocytes; Adipogenesis; Cell Differentiation; Humans; Inflammation; Insulin Resistance; Lipolysis; Obesity; Receptors, Purinergic P1; Thermogenesis

2017
Regulatory Role of N
    Journal of cellular biochemistry, 2017, Volume: 118, Issue:9

    Topics: Adenosine; Animals; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Humans; Methylation; Neoplasms; Obesity; RNA Processing, Post-Transcriptional; RNA, Neoplasm

2017
The putative roles of adenosine in insulin- and exercise-mediated regulation of glucose transport and glycogen metabolism in skeletal muscle.
    Canadian journal of applied physiology = Revue canadienne de physiologie appliquee, 2002, Volume: 27, Issue:2

    Topics: Adenosine; Animals; Diabetes Mellitus; Exercise; Glucose; Glucose Transporter Type 4; Glycogen; GTP-Binding Proteins; Homeostasis; Humans; Monosaccharide Transport Proteins; Muscle Contraction; Muscle Proteins; Muscle, Skeletal; Obesity; Physical Conditioning, Animal; Receptors, Purinergic P1; Signal Transduction; Xanthines

2002
[Recent research on lipolysis. Its biomedical importance].
    Gaceta medica de Mexico, 1981, Volume: 117, Issue:10

    Topics: Adenosine; Adrenergic beta-Antagonists; Animals; Calcium; Coronary Disease; Cyclic AMP; Diabetes Mellitus; Fatty Acids; Female; Hormones; Humans; Lipid Metabolism; Lipolysis; Mice; Obesity; Pregnancy

1981
Adenosine, prostaglandins and phosphodiesterase as targets for obesity pharmacotherapy.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1993, Volume: 17 Suppl 1

    Topics: Adenosine; Humans; Lipolysis; Obesity; Phosphoric Diester Hydrolases; Prostaglandins

1993
A review: The obese strain (OS) of chickens: an animal model with spontaneous autoimmune thyroiditis.
    Clinical immunology and immunopathology, 1974, Volume: 3, Issue:2

    Topics: Adenosine; Animals; Animals, Newborn; Autoantibodies; Autoimmune Diseases; B-Lymphocytes; Basement Membrane; Bursa of Fabricius; Chick Embryo; Chickens; Chromium Radioisotopes; Complement Fixation Tests; Disease Models, Animal; Fluorescent Antibody Technique; Hemagglutination Tests; Hypothyroidism; Immunization, Passive; Immunodiffusion; Iodine Radioisotopes; Obesity; Organ Specificity; Phenotype; Thyroglobulin; Thyroid Function Tests; Thyroid Gland; Thyroiditis; Thyroxine; Tritium

1974

Trials

3 trial(s) available for adenosine and Obesity

ArticleYear
Reduction of free fatty acids, safety, and pharmacokinetics of oral GS-9667, an A(1) adenosine receptor partial agonist.
    Journal of clinical pharmacology, 2013, Volume: 53, Issue:4

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adolescent; Adult; Fatty Acids, Nonesterified; Female; Humans; Male; Middle Aged; Obesity; Young Adult

2013
Effects of age, gender, obesity, and diabetes on the efficacy and safety of the selective A2A agonist regadenoson versus adenosine in myocardial perfusion imaging integrated ADVANCE-MPI trial results.
    JACC. Cardiovascular imaging, 2008, Volume: 1, Issue:3

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Adult; Age Factors; Aged; Aged, 80 and over; Body Mass Index; Coronary Circulation; Diabetes Complications; Double-Blind Method; Female; Humans; Image Interpretation, Computer-Assisted; Male; Middle Aged; Myocardial Ischemia; Myocardial Perfusion Imaging; Myocardium; Obesity; Patient Satisfaction; Predictive Value of Tests; Purines; Pyrazoles; Risk Assessment; Risk Factors; Sex Factors; Tomography, Emission-Computed, Single-Photon

2008
The effect of obesity on regadenoson-induced myocardial hyperemia: a quantitative magnetic resonance imaging study.
    The international journal of cardiovascular imaging, 2012, Volume: 28, Issue:6

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Adult; Body Mass Index; Contrast Media; Coronary Circulation; Drug Dosage Calculations; Female; Humans; Hyperemia; Infusions, Intravenous; Injections, Intravenous; Magnetic Resonance Imaging, Cine; Male; Meglumine; Middle Aged; Myocardial Perfusion Imaging; Obesity; Organometallic Compounds; Predictive Value of Tests; Purines; Pyrazoles; Time Factors; Utah; Vasodilator Agents

2012

Other Studies

55 other study(ies) available for adenosine and Obesity

ArticleYear
m
    Cell reports, 2021, 11-09, Volume: 37, Issue:6

    Topics: Adenosine; Animals; DNA Methylation; Female; Immunity, Innate; Macrophages; Male; Methyltransferases; Mice; Mice, Inbred C57BL; Mice, Knockout; Myeloid Cells; NF-kappa B; Non-alcoholic Fatty Liver Disease; Obesity; RNA, Messenger

2021
m6A Regulators in Human Adipose Tissue - Depot-Specificity and Correlation With Obesity.
    Frontiers in endocrinology, 2021, Volume: 12

    Topics: Adenosine; Adipose Tissue; Adult; Aged; AlkB Homolog 5, RNA Demethylase; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Cell Cycle Proteins; Cohort Studies; Epigenesis, Genetic; Female; Germany; Humans; Male; Middle Aged; Nerve Tissue Proteins; Obesity; Organ Specificity; Polymorphism, Single Nucleotide; RNA Processing, Post-Transcriptional; RNA Splicing Factors; RNA-Binding Proteins; RNA, Messenger

2021
Intermittent Fasting Improves High-Fat Diet-Induced Obesity Cardiomyopathy via Alleviating Lipid Deposition and Apoptosis and Decreasing m6A Methylation in the Heart.
    Nutrients, 2022, Jan-07, Volume: 14, Issue:2

    Topics: Adenosine; Animals; Apoptosis; Cardiomyopathies; Diet, High-Fat; Echocardiography; Fasting; Lipid Metabolism; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Obese; Myocardium; Obesity; Random Allocation; RNA, Messenger

2022
Being Overweight or Obese Is Associated with an Increased Platelet Reactivity Despite Dual Antiplatelet Therapy with Aspirin and Clopidogrel.
    Cardiovascular drugs and therapy, 2023, Volume: 37, Issue:4

    Topics: Adenosine; Adenosine Diphosphate; Aspirin; Blood Platelets; Clopidogrel; Humans; Obesity; Overweight; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticagrelor; Ticlopidine

2023
N6-Methyladenosine Demethylase FTO (Fat Mass and Obesity-Associated Protein) as a Novel Mediator of Statin Effects in Human Endothelial Cells.
    Arteriosclerosis, thrombosis, and vascular biology, 2022, Volume: 42, Issue:5

    Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Atorvastatin; Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intercellular Adhesion Molecule-1; Obesity; RNA, Messenger; Vascular Cell Adhesion Molecule-1

2022
Single-Molecule Counting of FTO in Human Breast Tissues Based on a Rolling Circle Transcription Amplification-Driven Clustered Regularly Interspaced Short Palindromic Repeat─Cas12a.
    Analytical chemistry, 2022, 08-16, Volume: 94, Issue:32

    Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; CRISPR-Cas Systems; Humans; Mammals; Neoplasms; Obesity

2022
m
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2022, Volume: 32, Issue:9

    Topics: Adenosine; AlkB Homolog 5, RNA Demethylase; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Humans; Obesity; RNA; RNA, Messenger

2022
Metabolomics Provides Insights into Renoprotective Effects of Semaglutide in Obese Mice.
    Drug design, development and therapy, 2022, Volume: 16

    Topics: Adenosine; Animals; Insulin Resistance; Kidney Diseases; Male; Mice; Mice, Inbred C57BL; Mice, Obese; NAD; Obesity

2022
METTL3 inhibits hepatic insulin sensitivity via N6-methyladenosine modification of Fasn mRNA and promoting fatty acid metabolism.
    Biochemical and biophysical research communications, 2019, 10-08, Volume: 518, Issue:1

    Topics: Adenosine; Animals; Dependovirus; Diabetes Mellitus, Type 2; Disease Models, Animal; Fatty Acid Synthase, Type I; Fatty Acids; Gene Deletion; Glucose; Hepatocytes; Homeostasis; Humans; Insulin Resistance; Liver; Methylation; Methyltransferases; Mice, Inbred C57BL; Mice, Knockout; Obesity; RNA, Messenger

2019
Adenosine accumulation causes metabolic disorders in testes and associates with lower testosterone level in obese mice.
    Molecular reproduction and development, 2020, Volume: 87, Issue:2

    Topics: Adenosine; Adenosine Monophosphate; Animals; Disease Models, Animal; Down-Regulation; Gene Expression; Male; Metabolic Diseases; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Testis; Testosterone; TOR Serine-Threonine Kinases; Up-Regulation

2020
Age-related muscle loss - novel target identified.
    Nature reviews. Endocrinology, 2020, Volume: 16, Issue:9

    Topics: Adenosine; Aging; Humans; Obesity; Receptor, Adenosine A2B; Sarcopenia

2020
Nitroxide-enhanced MRI of cardiovascular oxidative stress.
    NMR in biomedicine, 2020, Volume: 33, Issue:9

    Topics: Adenosine; Angiotensin II; Animals; Cardiovascular System; Cyclic N-Oxides; Diet, High-Fat; Dietary Sucrose; Disease Models, Animal; Magnetic Resonance Imaging; Male; Mice, Inbred C57BL; Myocardial Infarction; Nitrogen Oxides; Obesity; Oxidative Stress; Perfusion; Pyrrolidines

2020
Resveratrol Supplementation Attenuates Cognitive and Molecular Alterations under Maternal High-Fat Diet Intake: Epigenetic Inheritance over Generations.
    International journal of molecular sciences, 2021, Feb-01, Volume: 22, Issue:3

    Topics: Adenosine; Animals; Body Weight; Brain; Cognition; Diet, High-Fat; Dietary Supplements; DNA Methylation; Epigenesis, Genetic; Epigenomics; Female; Inflammation; Leptin; Male; Maternal Exposure; Maze Learning; Methylation; Mice; Neurodegenerative Diseases; Neuronal Plasticity; Obesity; Pregnancy; Pregnancy, Animal; Prenatal Exposure Delayed Effects; Resveratrol; Triglycerides

2021
N6-methyladenosine Demethylase FTO Induces the Dysfunctions of Ovarian Granulosa Cells by Upregulating Flotillin 2.
    Reproductive sciences (Thousand Oaks, Calif.), 2022, Volume: 29, Issue:4

    Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Female; Granulosa Cells; Humans; Insulin Resistance; Membrane Proteins; Obesity; Polycystic Ovary Syndrome; RNA, Messenger

2022
High plasma adenosine levels in overweight/obese pregnant women.
    Purinergic signalling, 2017, Volume: 13, Issue:4

    Topics: Adenosine; Adult; Body Mass Index; Cross-Sectional Studies; Diet; Female; Humans; Obesity; Overweight; Pregnancy; Pregnancy Complications; Weight Gain

2017
Pyruvate induces torpor in obese mice.
    Proceedings of the National Academy of Sciences of the United States of America, 2018, 01-23, Volume: 115, Issue:4

    Topics: Adenosine; Adipose Tissue, Brown; Animals; Brain; Insulin Resistance; Male; Mice, Inbred C57BL; Mice, Obese; Obesity; Pyruvic Acid; Torpor; Uncoupling Protein 1

2018
Maternal obesity aggravates the abnormality of porcine placenta by increasing N
    International journal of obesity (2005), 2018, Volume: 42, Issue:10

    Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Animals, Newborn; Disease Models, Animal; Female; Fetal Development; Lipid Metabolism; Obesity; Placenta; Pregnancy; Pregnancy Complications; Pregnancy, Animal; Swine; Swine Diseases

2018
Adenosine and adenosine-5'-monophosphate ingestion ameliorates abnormal glucose metabolism in mice fed a high-fat diet.
    BMC complementary and alternative medicine, 2018, Nov-14, Volume: 18, Issue:1

    Topics: Adenosine; Adenosine Monophosphate; AMP-Activated Protein Kinases; Animals; Blood Glucose; Diet, High-Fat; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Obesity; Phosphorylation

2018
Expression of CD73 and A2A receptors in cells from subjects with obesity and type 2 diabetes mellitus.
    Immunobiology, 2015, Volume: 220, Issue:8

    Topics: 5'-Nucleotidase; Adenosine; Adult; Antigens, CD; Apoptosis; Apyrase; Body Mass Index; CD8-Positive T-Lymphocytes; Diabetes Mellitus, Type 2; Gene Expression Regulation; GPI-Linked Proteins; Humans; Inflammation; Lymphocyte Subsets; Lymphocytes; Obesity; Phenethylamines; Receptor, Adenosine A2A; Triazines; Triazoles

2015
Human supraphysiological gestational weight gain and fetoplacental vascular dysfunction.
    International journal of obesity (2005), 2015, Volume: 39, Issue:8

    Topics: Adenosine; Adult; Biological Transport; Chile; Endothelium, Vascular; Female; Humans; Infant, Newborn; Nitric Oxide; Obesity; Placenta; Placental Circulation; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Signal Transduction; Umbilical Veins; Weight Gain

2015
The Demethylase Activity of FTO (Fat Mass and Obesity Associated Protein) Is Required for Preadipocyte Differentiation.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: 3T3-L1 Cells; Adenosine; Adipocytes; Adipogenesis; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Biomarkers; Cell Differentiation; DNA Methylation; DNA Modification Methylases; Gene Expression Profiling; Hypoglycemic Agents; Mice; Obesity; PPAR gamma; Proteins; RNA, Small Interfering; Rosiglitazone; Thiazolidinediones

2015
Ticagrelor and Rosuvastatin Have Additive Cardioprotective Effects via Adenosine.
    Cardiovascular drugs and therapy, 2016, Volume: 30, Issue:6

    Topics: Adenosine; Animals; Apoptosis Regulatory Proteins; CARD Signaling Adaptor Proteins; Cardiotonic Agents; Cyclooxygenase 2; Diabetes Mellitus, Experimental; Drug Synergism; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-1beta; Interleukin-6; Lipoxins; Male; Myocardial Reperfusion Injury; Myocardium; NLR Family, Pyrin Domain-Containing 3 Protein; Obesity; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Rats, Zucker; RNA, Messenger; Rosuvastatin Calcium; Ticagrelor

2016
Leptin replacement restores supraspinal cholinergic antinociception in leptin-deficient obese mice.
    The journal of pain, 2009, Volume: 10, Issue:8

    Topics: Acetylcholine; Adenosine; Animals; Carbachol; Cholinergic Agonists; Cholinesterase Inhibitors; Hot Temperature; Leptin; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Morphine; Neostigmine; Nicotine; Obesity; Pain; Pain Measurement; Pons; Time Factors

2009
Integration of skeletal muscle resistance arteriolar reactivity for perfusion responses in the metabolic syndrome.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 296, Issue:6

    Topics: Adenosine; Adrenergic alpha-Antagonists; Adrenergic Fibers; Animals; Antioxidants; Arachidonic Acid; Arterioles; Disease Models, Animal; Endothelium, Vascular; Hindlimb; Hyperemia; Hypoxia; Male; Metabolic Syndrome; Microcirculation; Muscle, Skeletal; Muscle, Smooth, Vascular; Obesity; Oxidative Stress; Rats; Rats, Zucker; Regional Blood Flow; Vascular Resistance; Vasoconstriction; Vasodilation; Vasodilator Agents

2009
Adipocyte-derived factor reduces vasodilatory capability in ob-/ob- mice.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 297, Issue:2

    Topics: Adenosine; Adipocytes; Animals; Arterioles; Glyburide; Hypoglycemic Agents; Intra-Abdominal Fat; KATP Channels; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Muscle, Skeletal; Muscle, Smooth, Vascular; Nitroprusside; Obesity; Vasodilation; Vasodilator Agents

2009
Different susceptibility of liver grafts from lean and obese Zucker rats to preservation injury.
    Cryobiology, 2009, Volume: 59, Issue:3

    Topics: Adenosine; Allopurinol; Animals; Cryopreservation; Fatty Liver; Glucose; Glutathione; Insulin; Liver Transplantation; Male; Obesity; Organ Preservation; Organ Preservation Solutions; Perfusion; Raffinose; Rats; Rats, Zucker; Reperfusion Injury; Tromethamine

2009
SPECT MIBI imaging for cardiac output and index in end stage renal disease.
    Hemodialysis international. International Symposium on Home Hemodialysis, 2011, Volume: 15, Issue:3

    Topics: Adenosine; Adult; Aged; Anti-Arrhythmia Agents; Body Mass Index; Exercise Test; Female; Hemoglobins; Humans; Kidney Failure, Chronic; Male; Middle Aged; Obesity; Radiography; Stroke Volume; Tomography, Emission-Computed, Single-Photon

2011
Elevated adenosine deaminase activity in overweight and obese Indian subjects.
    Archives of physiology and biochemistry, 2012, Volume: 118, Issue:1

    Topics: Adenosine; Adenosine Deaminase; Adipose Tissue; Adolescent; Adult; Aged; Body Composition; Body Mass Index; Fasting; Female; Humans; India; Inosine; Insulin Resistance; Male; Middle Aged; Obesity

2012
N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO.
    Nature chemical biology, 2011, Oct-16, Volume: 7, Issue:12

    Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Cell Nucleus; HeLa Cells; Humans; Methylation; Obesity; Oxidation-Reduction; Proteins; RNA, Messenger; Substrate Specificity

2011
Both BMI and waist circumference are associated with coronary vasoreactivity in overweight and obese men.
    Obesity facts, 2012, Volume: 5, Issue:5

    Topics: Adenosine; Adult; Body Mass Index; Coronary Circulation; Coronary Disease; Coronary Vessels; Humans; Male; Middle Aged; Obesity; Overweight; Waist Circumference; Waist-Hip Ratio; Young Adult

2012
Deletion of CD73 promotes dyslipidemia and intramyocellular lipid accumulation in muscle of mice.
    Archives of physiology and biochemistry, 2013, Volume: 119, Issue:2

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Monophosphate; Adipocytes; Adipose Tissue; Animals; Blood Glucose; Diet, High-Fat; Down-Regulation; Dyslipidemias; Gene Deletion; Homeostasis; Insulin; Lipid Metabolism; Lipolysis; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Skeletal; Muscles; Obesity; Phosphorylation; Proto-Oncogene Proteins c-akt

2013
High serum leptin is associated with attenuated coronary vasoreactivity.
    Obesity research, 2003, Volume: 11, Issue:6

    Topics: Adenosine; Adult; Blood Glucose; Coronary Circulation; Coronary Vessels; Fatty Acids, Nonesterified; Hemodynamics; Humans; Leptin; Male; Norepinephrine; Obesity; Tomography, Emission-Computed

2003
Feasibility of measuring coronary flow velocity and reserve in the left anterior descending coronary artery by transthoracic Doppler echocardiography in a relatively obese American population.
    Echocardiography (Mount Kisco, N.Y.), 2005, Volume: 22, Issue:3

    Topics: Adenosine; Adult; Aged; Aged, 80 and over; Blood Flow Velocity; Body Mass Index; Contrast Media; Coronary Circulation; Coronary Vessels; Echocardiography, Doppler; Echocardiography, Doppler, Color; Feasibility Studies; Female; Humans; Infusions, Intravenous; Japan; Male; Middle Aged; Obesity; United States; Vasodilator Agents

2005
Adenosinergic modulation of ventilation in obese zucker rats.
    Obesity research, 2005, Volume: 13, Issue:3

    Topics: Adenosine; Aminophylline; Animals; Carbon Dioxide; Hypercapnia; Hypoxia; Male; Obesity; Oxygen; Oxygen Consumption; Rats; Rats, Zucker; Respiration; Theophylline

2005
Short-term changes in inflammatory response protein (hsCRP) do not parallel with changes in coronary vasoreactivity in obese men.
    International journal of obesity (2005), 2006, Volume: 30, Issue:3

    Topics: Adenosine; Adult; Anti-Inflammatory Agents; Blood Glucose; C-Reactive Protein; Coronary Circulation; Coronary Vessels; Dexamethasone; Fatty Acids, Nonesterified; Glucose Clamp Technique; Hemodynamics; Humans; Insulin; Male; Obesity; Positron-Emission Tomography; Vascular Resistance

2006
Lymphocyte ecto-5'-nucleotidase in obese type 2 diabetic patients treated with gliclazide.
    Diabetes & metabolism, 2006, Volume: 32, Issue:2

    Topics: 5'-Nucleotidase; Adenosine; Body Mass Index; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Gliclazide; Humans; Hypoglycemic Agents; Lymphocytes; Middle Aged; Obesity; Triglycerides

2006
Hyperphagia-mediated obesity in transgenic mice misexpressing the RNA-editing enzyme ADAR2.
    The Journal of biological chemistry, 2007, Aug-03, Volume: 282, Issue:31

    Topics: Adenosine; Adenosine Deaminase; Animals; Caloric Restriction; Cytomegalovirus; Female; Inosine; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mutation; Obesity; Promoter Regions, Genetic; Rats; RNA-Binding Proteins

2007
Maximum activities of enzymes involved in adenosine metabolism in adipose tissue of rats and mice under conditions of variations in insulin sensitivity.
    Biochimica et biophysica acta, 1981, Aug-05, Volume: 676, Issue:1

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Adenosine Kinase; Adipose Tissue; Adrenalectomy; Animals; Diabetes Mellitus, Experimental; Female; Hypophysectomy; Insulin; Male; Mice; Nucleoside Deaminases; Nucleotidases; Obesity; Phosphotransferases; Pregnancy; Rats; Starvation

1981
Evidence for regulated coupling of A1 adenosine receptors by phosphorylation in Zucker rats.
    The American journal of physiology, 1995, Volume: 268, Issue:4 Pt 1

    Topics: Adenosine; Adenylyl Cyclases; Adipocytes; Animals; Cell Membrane; Colforsin; Cyclic AMP; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Iodine Radioisotopes; Iodobenzenes; Obesity; Phosphorylation; Proteins; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Rats, Zucker; Receptors, Purinergic P1

1995
Preservation of insulin secretory responses to P2 purinoceptor agonists in Zucker diabetic fatty rats.
    The American journal of physiology, 1996, Volume: 270, Issue:3 Pt 1

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Analysis of Variance; Animals; Blood Glucose; Body Weight; Calcium; Diabetes Mellitus; Diabetes Mellitus, Type 2; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Obesity; Perfusion; Potassium Chloride; Purinergic P2 Receptor Agonists; Rats; Rats, Wistar; Rats, Zucker; Reference Values; Thionucleotides; Time Factors

1996
Cellular insulin resistance in adipocytes from obese polycystic ovary syndrome subjects involves adenosine modulation of insulin sensitivity.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:5

    Topics: Adenosine; Adipocytes; Adrenergic beta-Agonists; Adult; Female; Follicle Stimulating Hormone; Glucose; Humans; Insulin; Insulin Resistance; Isoproterenol; Lipolysis; Luteinizing Hormone; Obesity; Polycystic Ovary Syndrome; Testosterone

1997
Metabolic and cardiovascular effects of the adenosine A1 receptor agonist N6-(p-sulfophenyl)adenosine in diabetic Zucker rats: influence of the disease on the selectivity of action.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:1

    Topics: Adenosine; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Hemodynamics; Insulin; Lipolysis; Male; Obesity; Purinergic P1 Receptor Agonists; Rats; Rats, Zucker

1998
The mechanism of injury in a steatotic liver graft during cold preservation.
    Transplantation, 1999, Jan-27, Volume: 67, Issue:2

    Topics: Adenosine; Allopurinol; Animals; Cell Membrane; Cholesterol; Fatty Acids; Fatty Liver; Glutathione; Insulin; Isotonic Solutions; Liver; Liver Transplantation; Membrane Fluidity; Microscopy, Electron; Obesity; Organ Preservation; Organ Preservation Solutions; Phospholipids; Raffinose; Rats; Rats, Zucker; Ringer's Lactate; Thinness; Time Factors; Triglycerides

1999
Leptin-induced lipolysis opposes the tonic inhibition of endogenous adenosine in white adipocytes.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2001, Volume: 15, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenylate Cyclase Toxin; Adipocytes; Adipose Tissue; Animals; Bucladesine; Cells, Cultured; Colforsin; Kinetics; Leptin; Lipolysis; Male; Obesity; Purinergic P1 Receptor Antagonists; Rats; Rats, Mutant Strains; Rats, Zucker; Recombinant Proteins; Signal Transduction; Virulence Factors, Bordetella

2001
The potential role of adenosine in the pathophysiology of the insulin resistance syndrome.
    Atherosclerosis, 2001, Volume: 155, Issue:2

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adipose Tissue; Animals; Coronary Disease; Diabetes Mellitus, Type 2; Erythropoiesis; Fatty Acids; Heart Rate; Hematocrit; Humans; Hyperinsulinism; Hypertrophy; Insulin Resistance; Islets of Langerhans; Mitochondria; Mitochondrial ADP, ATP Translocases; Models, Biological; Natriuresis; Obesity; Oxidative Phosphorylation; Renal Circulation; Risk Factors; Sodium; Superoxides; Sympathetic Nervous System; Uric Acid; Vasodilation

2001
Obesity is independently associated with coronary endothelial dysfunction in patients with normal or mildly diseased coronary arteries.
    Journal of the American College of Cardiology, 2001, Volume: 37, Issue:6

    Topics: Acetylcholine; Adenosine; Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Analysis of Variance; Blood Flow Velocity; Body Mass Index; Case-Control Studies; Coronary Angiography; Coronary Circulation; Coronary Disease; Cross-Sectional Studies; Endothelium, Vascular; Female; Humans; Male; Middle Aged; Multivariate Analysis; Nitroglycerin; Obesity; Odds Ratio; Risk Factors; Severity of Illness Index; Vasodilator Agents

2001
Obesity affects myocardial vasoreactivity and coronary flow response to insulin.
    Obesity research, 2002, Volume: 10, Issue:7

    Topics: Adenosine; Adult; Blood Flow Velocity; Blood Glucose; Blood Pressure; Body Composition; Body Mass Index; Coronary Circulation; Heart; Heart Rate; Humans; Hyperinsulinism; Insulin; Male; Obesity; Oxygen Radioisotopes; Tomography, Emission-Computed; Water

2002
Potentiation of the thermogenic antiobesity effects of ephedrine by dietary methylxanthines: adenosine antagonism or phosphodiesterase inhibition?
    Metabolism: clinical and experimental, 1992, Volume: 41, Issue:11

    Topics: Adenosine; Adipose Tissue, Brown; Animals; Caffeine; Diet; Dose-Response Relationship, Drug; Drug Synergism; Eating; Ephedrine; Fasting; Hot Temperature; Male; Obesity; Oxygen Consumption; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Sympathectomy, Chemical; Theobromine; Xanthines

1992
Attenuated adenosine-sensitivity and decreased adenosine-receptor number in adipocyte plasma membranes in human obesity.
    The Biochemical journal, 1991, Oct-01, Volume: 279 ( Pt 1)

    Topics: Adenosine; Adenylyl Cyclases; Adipose Tissue; Body Weight; Cell Membrane; Colforsin; Cyclic AMP; Enzyme Activation; Glucose; Humans; Isoproterenol; Obesity; Phenylisopropyladenosine; Receptors, Purinergic; Xanthines

1991
Winner of the 1988 NAASO Young Investigator Award. Regulation of fat cell adenylate cyclase in young Zucker (fa/fa) rats: alterations in GTP sensitivity of adenosine A1 mediated inhibition.
    International journal of obesity, 1990, Volume: 14 Suppl 3

    Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adipose Tissue; Animals; Awards and Prizes; Cell Membrane; Cyclic AMP; Dietetics; Female; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Lipolysis; Obesity; Phenylisopropyladenosine; Rats; Rats, Zucker; Receptors, Purinergic; Societies, Medical; United States

1990
A1-adenosine receptor-mediated inhibition of adipocyte adenylate cyclase and lipolysis in Zucker rats.
    The American journal of physiology, 1989, Volume: 257, Issue:6 Pt 1

    Topics: Adenosine; Adenosine Deaminase; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adipose Tissue; Animals; Cells, Cultured; Cyclic AMP; Female; Glycerol; Lipolysis; Obesity; Pertussis Toxin; Phenylisopropyladenosine; Rats; Rats, Zucker; Receptors, Purinergic; Theophylline; Virulence Factors, Bordetella

1989
Adrenergic regulation of lipolysis in abdominal adipocytes of obese subjects during caloric restriction: reversal of catecholamine action caused by relief of endogenous inhibition.
    European journal of clinical investigation, 1985, Volume: 15, Issue:1

    Topics: Adenosine; Adipose Tissue; Adolescent; Adrenergic Agonists; Adult; Aged; Catecholamines; Cells, Cultured; Clonidine; Energy Intake; Female; Glycerol; Humans; Isoproterenol; Lipolysis; Male; Middle Aged; Obesity; Starvation

1985
Maximal activities of enzymes involved in adenosine metabolism in muscle and adipose tissue of rats under conditions of variations in insulin sensitivity.
    FEBS letters, 1985, Feb-11, Volume: 181, Issue:1

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Adenosine Kinase; Adipose Tissue; Adrenalectomy; Age Factors; Animals; Insulin; Male; Muscles; Nucleotidases; Obesity; Physical Exertion; Rats; Rats, Zucker

1985
Attenuated adenosine R-site effect in adipocytes in obesity.
    Metabolism: clinical and experimental, 1986, Volume: 35, Issue:2

    Topics: Adenosine; Adipose Tissue; Body Weight; Cyclic AMP; Humans; Isoproterenol; Lipolysis; Obesity; Phenylisopropyladenosine; Receptors, Cell Surface; Receptors, Purinergic

1986
Antilipolytic effects of N6-phenylisopropyladenosine and prostaglandin E2 in fat-cells of obese volunteers before and during energy restriction.
    The Biochemical journal, 1985, Nov-01, Volume: 231, Issue:3

    Topics: Adenosine; Adenosine Deaminase; Adipose Tissue; Adult; Dinoprostone; Female; Glycerol; Humans; In Vitro Techniques; Isoproterenol; Lipolysis; Male; Obesity; Phenylisopropyladenosine; Prostaglandins E; Starvation

1985
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