Compounds > vx-745
Page last updated: 2024-09-05

vx-745 and wortmannin

vx-745 has been researched along with wortmannin in 1 studies

Compound Research Comparison

Studies
(vx-745)		Trials
(vx-745)		Recent Studies (post-2010)
(vx-745)		Studies
(wortmannin)		Trials
(wortmannin)		Recent Studies (post-2010) (wortmannin)
581354,0662726

Protein Interaction Comparison

ProteinTaxonomyvx-745 (IC50)wortmannin (IC50)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformHomo sapiens (human)0.0465
Myosin light chain kinase, smooth muscleGallus gallus (chicken)0.26
Metabotropic glutamate receptor 1Rattus norvegicus (Norway rat)0.0085
Phosphatidylinositol 3-kinase regulatory subunit alphaHomo sapiens (human)0.2368
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformHomo sapiens (human)0.1309
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformHomo sapiens (human)0.0493
Serine/threonine-protein kinase mTORHomo sapiens (human)0.04
Phosphatidylinositol 4-kinase alphaHomo sapiens (human)0.28
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Homo sapiens (human)0.0492
Serine/threonine-protein kinase PLK1Homo sapiens (human)0.4433
Myosin light chain kinase, smooth muscleHomo sapiens (human)2.3567
Phosphoinositide 3-kinase regulatory subunit 5Homo sapiens (human)0.019
Serine/threonine-protein kinase PLK3Homo sapiens (human)0.1057
Phosphatidylinositol 4-kinase betaHomo sapiens (human)0.44

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Egbert, M; Keserű, GM; Vajda, S; Whitty, A1

Other Studies

1 other study(ies) available for vx-745 and wortmannin

ArticleYear
Why Some Targets Benefit from beyond Rule of Five Drugs.
    Journal of medicinal chemistry, 2019, 11-27, Volume: 62, Issue:22

    Topics: Binding Sites; Drug Discovery; Ligands; Molecular Weight; Protein Binding

2019