vx-745 has been researched along with tak-715 in 2 studies
| Studies (vx-745) | Trials (vx-745) | Recent Studies (post-2010) (vx-745) | Studies (tak-715) | Trials (tak-715) | Recent Studies (post-2010) (tak-715) |
|---|---|---|---|---|---|
| 58 | 1 | 35 | 16 | 0 | 13 |
| Protein | Taxonomy | vx-745 (IC50) | tak-715 (IC50) |
|---|---|---|---|
| Mitogen-activated protein kinase 13 | Homo sapiens (human) | 0.24 | |
| Mitogen-activated protein kinase 12 | Homo sapiens (human) | 0.24 | |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | 0.22 | |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | 0.1235 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hajduk, PJ; Johnson, EF; Kifle, L; Merta, PJ; Metz, JT; Soni, NB | 1 |
| Azevedo, R; de Vlieg, J; Kazemier, B; Oubrie, A; Raaijmakers, H; van Zeeland, M | 1 |
2 other study(ies) available for vx-745 and tak-715
| Article | Year |
|---|---|
Navigating the kinome.
Topics: Drug Design; Pharmacogenetics; Protein Kinases; Proteome; Systems Biology | 2011 |
X-ray structure of p38α bound to TAK-715: comparison with three classic inhibitors.
Topics: Adenosine Triphosphate; Benzamides; Catalytic Domain; Cloning, Molecular; Crystallization; Crystallography, X-Ray; Humans; Imidazoles; Indoles; Ligands; p38 Mitogen-Activated Protein Kinases; Protein Binding; Protein Conformation; Protein Kinase Inhibitors; Pyridazines; Pyridines; Pyrimidines; Structure-Activity Relationship; Thiazoles | 2012 |