vx-745 has been researched along with ispinesib in 2 studies
| Studies (vx-745) | Trials (vx-745) | Recent Studies (post-2010) (vx-745) | Studies (ispinesib) | Trials (ispinesib) | Recent Studies (post-2010) (ispinesib) |
|---|---|---|---|---|---|
| 58 | 1 | 35 | 57 | 11 | 34 |
| Protein | Taxonomy | vx-745 (IC50) | ispinesib (IC50) |
|---|---|---|---|
| Cytochrome P450 3A4 | Homo sapiens (human) | 4.1 | |
| Kinesin-like protein KIF11 | Homo sapiens (human) | 0.026 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 4.81 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ | 1 |
| Egbert, M; Keserű, GM; Vajda, S; Whitty, A | 1 |
2 other study(ies) available for vx-745 and ispinesib
| Article | Year |
|---|---|
Identification of potent Yes1 kinase inhibitors using a library screening approach.
Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
Why Some Targets Benefit from beyond Rule of Five Drugs.
Topics: Binding Sites; Drug Discovery; Ligands; Molecular Weight; Protein Binding | 2019 |