tak 779 has been researched along with zidovudine in 3 studies
| Studies (tak 779) | Trials (tak 779) | Recent Studies (post-2010) (tak 779) | Studies (zidovudine) | Trials (zidovudine) | Recent Studies (post-2010) (zidovudine) |
|---|---|---|---|---|---|
| 118 | 1 | 35 | 10,180 | 1,399 | 1,188 |
| Protein | Taxonomy | tak 779 (IC50) | zidovudine (IC50) |
|---|---|---|---|
| Thymidine kinase, cytosolic | Homo sapiens (human) | 3 | |
| Reverse transcriptase/RNaseH | Human immunodeficiency virus 1 | 0.6633 | |
| Protease | Human immunodeficiency virus 1 | 0.015 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fukushima, D; Hisaichi, K; Jenkinson, S; Kazmierski, WM; Maeda, K; Matsunaga, N; Minamoto, C; Mitsuya, H; Nakai, H; Nishiyama, T; Nishizawa, R; Sagawa, K; Shibayama, S; Tada, H; Takaoka, Y | 1 |
| Fukushima, D; Hisaichi, K; Maeda, K; Minamoto, C; Mitsuya, H; Murota, M; Nakai, H; Nishiyama, T; Nishizawa, R; Sagawa, K; Shibayama, S; Tada, H; Takaoka, Y | 1 |
| Bond, VC; Cox, BD; Huang, MB; Krystal, M; Lee, S; Li, Z; Liotta, DC; Prosser, AR; Snyder, JP; Sun, Y; Wilson, LJ | 1 |
3 other study(ies) available for tak 779 and zidovudine
| Article | Year |
|---|---|
Spirodiketopiperazine-based CCR5 antagonist: discovery of an antiretroviral drug candidate.
Topics: Administration, Oral; Animals; Anti-HIV Agents; CCR5 Receptor Antagonists; Cell Line, Tumor; Diketopiperazines; Drug Evaluation, Preclinical; HIV Core Protein p24; HIV-1; Humans; Microsomes, Liver; Rats; Receptors, CCR5; Spiro Compounds; Stereoisomerism | 2011 |
Discovery of 4-[4-({(3R)-1-butyl-3-[(R)-cyclohexyl(hydroxy)methyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl}methyl)phenoxy]benzoic acid hydrochloride: a highly potent orally available CCR5 selective antagonist.
Topics: Administration, Oral; Animals; Anti-HIV Agents; Benzoates; CCR5 Receptor Antagonists; Diketopiperazines; Dogs; Drug Evaluation, Preclinical; Guinea Pigs; Haplorhini; Humans; Rabbits; Rats; Receptors, CCR5; Structure-Activity Relationship | 2011 |
Pyrazolo-Piperidines Exhibit Dual Inhibition of CCR5/CXCR4 HIV Entry and Reverse Transcriptase.
Topics: | 2015 |