tak 779 has been researched along with plerixafor in 15 studies
Studies (tak 779) | Trials (tak 779) | Recent Studies (post-2010) (tak 779) | Studies (plerixafor) | Trials (plerixafor) | Recent Studies (post-2010) (plerixafor) |
---|---|---|---|---|---|
118 | 1 | 35 | 1,312 | 113 | 930 |
Protein | Taxonomy | tak 779 (IC50) | plerixafor (IC50) |
---|---|---|---|
C-X-C chemokine receptor type 4 | Rattus norvegicus (Norway rat) | 0.108 | |
C-C chemokine receptor type 2 | Homo sapiens (human) | 0.0001 | |
C-X-C chemokine receptor type 4 | Homo sapiens (human) | 0.3717 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 9 (60.00) | 29.6817 |
2010's | 6 (40.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Baba, M; Miyake, H; Okamoto, M; Takashima, K; Wang, X | 1 |
Parmentier, M; Sohy, D; Springael, JY | 1 |
Chen, CH; Ho, P; Huang, L; Lai, W; Li, Z; Montefiori, D | 1 |
Ballweber, L; Fialkow, M; Hladik, F; Kreger, A; Lentz, G; McElrath, MJ; Robinson, B; Sakchalathorn, P; Terker, A | 1 |
Horuk, R; Pease, J | 1 |
Bond, VC; Cox, BD; Huang, MB; Krystal, M; Lee, S; Li, Z; Liotta, DC; Prosser, AR; Snyder, JP; Sun, Y; Wilson, LJ | 1 |
Gettie, A; Lal, RB; Lou, B; Marx, PA; Moore, JP; Zhang, Y | 1 |
Gordon, CA; Moore, JP; Spenlehauer, C; Trkola, A | 1 |
Maddon, PJ; Olson, WC | 1 |
Alespeiti, G; Debnath, AK; He, Y; Zhao, Q | 1 |
Armand-Ugón, M; Clotet, B; Esté, JA; Moncunill, G; Pauls, E | 1 |
de Nadai, P; Guillabert, A; Javitch, JA; Parmentier, M; Sohy, D; Springael, JY; Urizar, E; Yano, H | 1 |
Abergel, J; Branch, A; Chang, TL; Ding, J; Garber, J; Gutierrez, J; Hubner, W; Klepper, A; Mosoian, A; Rapista, A; Schiano, T; Walewski, J | 1 |
Chan, LW; Pei, XM; Sin, TK; Siu, PM; Wong, CS; Yip, SP; Yu, AP; Yung, BY | 1 |
Arakelyan, A; Chernomordik, LV; Margolis, LB; Marin, M; Melikov, K; Melikyan, GB; Villasmil, R; Zaitsev, E; Zaitseva, E | 1 |
1 review(s) available for tak 779 and plerixafor
Article | Year |
---|---|
Resistance to HIV-1 entry inhibitors.
Topics: Amides; Anti-HIV Agents; Benzylamines; CD4 Immunoadhesins; Cyclams; Drug Resistance, Viral; Enfuvirtide; Heterocyclic Compounds; HIV Envelope Protein gp41; HIV Infections; HIV-1; Humans; Peptide Fragments; Piperazines; Quaternary Ammonium Compounds | 2003 |
14 other study(ies) available for tak 779 and plerixafor
Article | Year |
---|---|
Isolation and characterization of human immunodeficiency virus type 1 resistant to the small-molecule CCR5 antagonist TAK-652.
Topics: Amino Acid Sequence; Anti-HIV Agents; CCR5 Receptor Antagonists; Cells, Cultured; Cytopathogenic Effect, Viral; Drug Resistance, Viral; HIV Infections; HIV-1; Humans; Imidazoles; Leukocytes, Mononuclear; Molecular Sequence Data; Sulfoxides; Virus Replication | 2007 |
Allosteric transinhibition by specific antagonists in CCR2/CXCR4 heterodimers.
Topics: Allosteric Site; Animals; Binding, Competitive; Calcium; Chemotaxis; CHO Cells; Cricetinae; Cricetulus; Dimerization; Humans; Inhibitory Concentration 50; Kinetics; Protein Binding; Receptors, CCR2; Receptors, CXCR4; T-Lymphocytes | 2007 |
Betulinic acid derivatives that target gp120 and inhibit multiple genetic subtypes of human immunodeficiency virus type 1.
Topics: Animals; Anti-HIV Agents; Betulinic Acid; Cell Line; Chlorocebus aethiops; COS Cells; Drug Resistance, Viral; HIV Envelope Protein gp120; HIV Fusion Inhibitors; HIV-1; Humans; Membrane Fusion; Microbial Sensitivity Tests; Models, Molecular; Pentacyclic Triterpenes; Peptide Fragments; Triterpenes | 2008 |
Ex vivo comparison of microbicide efficacies for preventing HIV-1 genomic integration in intraepithelial vaginal cells.
Topics: Adult; Anti-HIV Agents; Benzothiepins; Cells, Cultured; Enfuvirtide; Female; Flow Cytometry; Genotype; HIV Envelope Protein gp41; HIV Infections; HIV Integrase Inhibitors; HIV-1; Humans; In Vitro Techniques; Microscopy, Confocal; Peptide Fragments; Polymerase Chain Reaction; Virus Integration | 2010 |
Chemokine receptor antagonists.
Topics: Animals; Autoimmune Diseases; Humans; Receptors, Chemokine | 2012 |
Pyrazolo-Piperidines Exhibit Dual Inhibition of CCR5/CXCR4 HIV Entry and Reverse Transcriptase.
Topics: | 2015 |
Use of inhibitors to evaluate coreceptor usage by simian and simian/human immunodeficiency viruses and human immunodeficiency virus type 2 in primary cells.
Topics: Amides; Animals; Anti-HIV Agents; Benzylamines; CD4 Antigens; Cell Line; Chemokine CCL5; Cyclams; Heterocyclic Compounds; HIV-1; HIV-2; Humans; Leukocytes, Mononuclear; Lymphocytes; Macaca; Quaternary Ammonium Compounds; Receptors, CCR2; Receptors, CCR3; Receptors, CCR5; Receptors, Chemokine; Receptors, HIV; Receptors, Virus; Simian Immunodeficiency Virus; Transfection; Tumor Cells, Cultured; Virus Replication | 2000 |
A luciferase-reporter gene-expressing T-cell line facilitates neutralization and drug-sensitivity assays that use either R5 or X4 strains of human immunodeficiency virus type 1.
Topics: Amides; Anti-HIV Agents; Antibodies, Viral; Benzylamines; CCR5 Receptor Antagonists; Cell Line; Cell Line, Transformed; Cyclams; Drug Evaluation, Preclinical; Gene Expression; Genes, Reporter; Heterocyclic Compounds; HIV Core Protein p24; HIV-1; Humans; Luciferases; Neutralization Tests; Quaternary Ammonium Compounds; Receptors, CCR5; Receptors, CXCR4; T-Lymphocytes | 2001 |
A novel assay to identify entry inhibitors that block binding of HIV-1 gp120 to CCR5.
Topics: Amides; Animals; Anti-HIV Agents; Benzylamines; CCR5 Receptor Antagonists; CD4 Antigens; Cell Line; Cyclams; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Heterocyclic Compounds; HIV Envelope Protein gp120; HIV Infections; HIV-1; Protein Conformation; Quaternary Ammonium Compounds; Receptors, CCR5; Receptors, CXCR4; Virulence; Virus Replication | 2004 |
HIV-1 escape to CCR5 coreceptor antagonism through selection of CXCR4-using variants in vitro.
Topics: Amides; Amino Acid Sequence; Benzylamines; CCR5 Receptor Antagonists; Cell Line, Transformed; Cell Line, Tumor; Cells, Cultured; Cyclams; Evolution, Molecular; Genetic Variation; Heterocyclic Compounds; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Leukocytes, Mononuclear; Molecular Sequence Data; Peptide Fragments; Quaternary Ammonium Compounds; Receptors, CCR5; Receptors, CXCR4; Reverse Transcriptase Inhibitors; Sequence Alignment; Time Factors; Virus Attachment | 2008 |
Hetero-oligomerization of CCR2, CCR5, and CXCR4 and the protean effects of "selective" antagonists.
Topics: Amides; Animals; Benzylamines; CCR5 Receptor Antagonists; Cell Line; Cells, Cultured; Cyclams; Heterocyclic Compounds; Humans; Mice; Mice, Inbred BALB C; Monocytes; Protein Multimerization; Quaternary Ammonium Compounds; Receptors, CCR2; Receptors, CCR5; Receptors, CXCR4; T-Lymphocytes | 2009 |
Human peritoneal macrophages from ascitic fluid can be infected by a broad range of HIV-1 isolates.
Topics: Amides; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Ascitic Fluid; Benzylamines; Cells, Cultured; Cyclams; Gene Expression Profiling; Heterocyclic Compounds; HIV Fusion Inhibitors; HIV-1; Humans; Macrophages, Peritoneal; Quaternary Ammonium Compounds; Receptors, CCR5; Receptors, CXCR4; Receptors, HIV; Virus Internalization | 2010 |
[D-Lys3]-GHRP-6 exhibits pro-autophagic effects on skeletal muscle.
Topics: Amides; Animals; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Benzylamines; Cyclams; Doxorubicin; Heterocyclic Compounds; Male; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Muscle Cells; Muscle, Skeletal; Oligopeptides; Piperidines; Quaternary Ammonium Compounds; Quinazolinones; Receptors, CXCR4; Signal Transduction | 2015 |
Fusion Stage of HIV-1 Entry Depends on Virus-Induced Cell Surface Exposure of Phosphatidylserine.
Topics: Amides; Anoctamins; Antibodies, Monoclonal; Benzylamines; Calcium; CD4 Antigens; Cell Line; Cell Membrane; Cyclams; HEK293 Cells; HeLa Cells; Heterocyclic Compounds; HIV Infections; HIV-1; Host-Pathogen Interactions; Humans; Membrane Fusion; Phosphatidylserines; Phospholipid Transfer Proteins; Quaternary Ammonium Compounds; Receptors, CCR5; Receptors, CXCR4; Signal Transduction; Viral Envelope Proteins; Virus Activation; Virus Attachment; Virus Internalization; Virus Replication | 2017 |