Compounds > sym 2081
Page last updated: 2024-08-26

sym 2081 and kainic acid

sym 2081 has been researched along with kainic acid in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gu, ZQ; Hesson, DP; Maccecchini, ML; Pelletier, JC; Skolnick, P; Zhou, LM1
Baker, SR; Ballyk, BA; Bleakman, D; Collado, I; Domínguez, C; Escribano, A; Ezquerra, J; Goldsworthy, J; Hoo, K; Kamboj, RK; Mateo, AI; Pedregal, C; Rubio, A1
Bolte, J; Bunch, L; Chapelet, M; Gefflaut, T; Nielsen, B; Pickering, DS; Pu, X; Sagot, E; Stensbøl, TB; Umberti, M1
Briel, D; Kronbach, C; Rybak, A; Unverferth, K1
Amir, A; Brindisi, M; Butini, S; Campiani, G; Coccone, SS; Frydenvang, K; Gemma, S; Guarino, E; Kastrup, JS; Kumar, V; Maramai, S; Novellino, E; Pickering, DS; Valadés, EA; Valenti, S; Venskutonyte, R1

Other Studies

5 other study(ies) available for sym 2081 and kainic acid

ArticleYear
Synthesis, resolution, and biological evaluation of the four stereoisomers of 4-methylglutamic acid: selective probes of kainate receptors.
    Journal of medicinal chemistry, 1995, Jul-07, Volume: 38, Issue:14

    Topics: Animals; Glutamates; Molecular Probes; Radioligand Assay; Rats; Receptors, Kainic Acid; Stereoisomerism

1995
4-Alkyl- and 4-cinnamylglutamic acid analogues are potent GluR5 kainate receptor agonists.
    Journal of medicinal chemistry, 2000, May-18, Volume: 43, Issue:10

    Topics: Acetylene; Cell Line; Cells, Cultured; Electrophysiology; Ganglia, Spinal; Glutamates; Humans; Molecular Structure; Neurons; Patch-Clamp Techniques; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship

2000
Chemo-enzymatic synthesis of a series of 2,4-syn-functionalized (S)-glutamate analogues: new insight into the structure-activity relation of ionotropic glutamate receptor subtypes 5, 6, and 7.
    Journal of medicinal chemistry, 2008, Jul-24, Volume: 51, Issue:14

    Topics: Amination; Animals; Glutamic Acid; Magnetic Resonance Spectroscopy; Mass Spectrometry; Rats; Receptors, Glutamate; Spectrophotometry, Infrared; Structure-Activity Relationship; Synaptosomes

2008
Substituted 2-aminothiopen-derivatives: a potential new class of GluR6-antagonists.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:1

    Topics: Animals; Cell Line; GluK2 Kainate Receptor; High-Throughput Screening Assays; Humans; Inhibitory Concentration 50; Receptors, Kainic Acid; Substrate Specificity; Thiophenes

2010
Selective kainate receptor (GluK1) ligands structurally based upon 1H-cyclopentapyrimidin-2,4(1H,3H)-dione: synthesis, molecular modeling, and pharmacological and biostructural characterization.
    Journal of medicinal chemistry, 2011, Jul-14, Volume: 54, Issue:13

    Topics: Animals; Cell Line; Cricetinae; Crystallography, X-Ray; Female; Ligands; Models, Molecular; Oocytes; Patch-Clamp Techniques; Protein Conformation; Pyrimidines; Rats; Receptors, Kainic Acid; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship; Thiophenes; Xenopus laevis

2011