sr 95531 has been researched along with baclofen in 24 studies
| Studies (sr 95531) | Trials (sr 95531) | Recent Studies (post-2010) (sr 95531) | Studies (baclofen) | Trials (baclofen) | Recent Studies (post-2010) (baclofen) |
|---|---|---|---|---|---|
| 610 | 0 | 209 | 6,017 | 372 | 1,535 |
| Protein | Taxonomy | sr 95531 (IC50) | baclofen (IC50) |
|---|---|---|---|
| Gamma-aminobutyric acid type B receptor subunit 2 | Homo sapiens (human) | 0.05 | |
| Gamma-aminobutyric acid type B receptor subunit 2 | Rattus norvegicus (Norway rat) | 0.2762 | |
| Gamma-aminobutyric acid type B receptor subunit 1 | Homo sapiens (human) | 0.05 | |
| Gamma-aminobutyric acid type B receptor subunit 1 | Rattus norvegicus (Norway rat) | 0.2762 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.17) | 18.7374 |
| 1990's | 11 (45.83) | 18.2507 |
| 2000's | 8 (33.33) | 29.6817 |
| 2010's | 4 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bay, T; Bundgaard, C; Clausen, RP; Frølund, B; Kehler, J; Marek, A; Pedersen, MH; Vogensen, SB; Wellendorph, P | 1 |
| Scarth, BA; Shaw, C | 1 |
| Catt, KJ; Stojilković, SS; Virmani, MA | 1 |
| Balcar, VJ; Dreher, B | 1 |
| Asaro, D; Pellegrini, G; Pittaluga, A; Raiteri, M | 1 |
| Goudreau, JL; Lookingland, KJ; Moore, KE; Wagner, EJ | 2 |
| Chuang, DM; Yu, O | 1 |
| Kathmann, M; Malinowska, B; Schlicker, E | 1 |
| Choi, SR; Choi, YS; Kim, YH; Song, DK; Suh, HW | 1 |
| Feltz, P; Hayar, A; Piguet, P | 1 |
| Choi, IG; Huh, SO; Ihn, BM; Jung, JS; Kim, YH; Song, DK; Suh, HW | 1 |
| Paladini, CA; Tepper, JM | 1 |
| Huh, SO; Kim, YH; Lee, KC; Song, DK; Suh, HW | 1 |
| Guyenet, PG; Hayar, A | 1 |
| Abraini, JH; Balon, N; Kriem, B; Risso, JJ; Rostain, JC | 1 |
| Ackerson, LC; Galvan, A; Maidment, NT; Smith, Y; Villalba, RM; West, SM; Wichmann, T | 1 |
| Kaneda, K; Kita, H | 1 |
| Gao, J; Gao, XY; Liao, ZH; Shi, Z; Wang, W; Zhong, MK; Zhou, LM; Zhu, GQ | 1 |
| Friedrich, RW; Tabor, R; Yaksi, E | 1 |
| Dvorzhak, A; Grantyn, R; Kirischuk, S; Kirmse, K | 1 |
| Antal, K; Emri, Z; Katarova, Z; Máté, Z; Schwirtlich, M; Szabó, G | 1 |
| Edeline, JM; Gaucher, Q; Gourévitch, B; Huetz, C | 1 |
| Chen, Q; Ding, L; Gao, R; Gao, XY; Kang, YM; Li, YH; Xiong, XQ; Zhu, GQ | 1 |
24 other study(ies) available for sr 95531 and baclofen
| Article | Year |
|---|---|
New synthesis and tritium labeling of a selective ligand for studying high-affinity γ-hydroxybutyrate (GHB) binding sites.
Topics: Animals; Benzocycloheptenes; Binding Sites; Binding, Competitive; Brain; Carboxylic Acids; Cell Line; Central Nervous System; Cyclopentanes; Drug Stability; gamma-Aminobutyric Acid; Hydroxybutyrates; Kinetics; Ligands; Male; Models, Chemical; Molecular Structure; Radioligand Assay; Rats; Rats, Sprague-Dawley; Synaptic Membranes; Tritium | 2013 |
Age-dependent regulation of GABAA receptors in neocortex.
Topics: Aging; Animals; Baclofen; Cats; Cerebral Cortex; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kinetics; Muscimol; Pyridazines; Rats; Rats, Wistar; Receptors, GABA-A; Veratridine | 1992 |
Stimulation of luteinizing hormone release by gamma-aminobutyric acid (GABA) agonists: mediation by GABAA-type receptors and activation of chloride and voltage-sensitive calcium channels.
Topics: Amino Acid Sequence; Animals; Baclofen; Calcium Channels; Cells, Cultured; Chloride Channels; Chlorides; Female; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Isoxazoles; Luteinizing Hormone; Membrane Proteins; Molecular Sequence Data; Muscimol; Nifedipine; Pituitary Gland, Anterior; Pyridazines; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1990 |
Neurochemical correlates of gamma-aminobutyrate (GABA) inhibition in cat visual cortex.
Topics: Animals; Baclofen; Calcium; Cats; Cell Membrane; Female; GABA Antagonists; gamma-Aminobutyric Acid; Isonicotinic Acids; Isoxazoles; Male; Neurons; Potassium; Pyridazines; Receptors, GABA-A; Visual Cortex | 1990 |
Studies on [3H]GABA and endogenous GABA release in rat cerebral cortex suggest the presence of autoreceptors of the GABAB type.
Topics: Animals; Anticonvulsants; Baclofen; Bicuculline; Cerebral Cortex; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Median Eminence; Nipecotic Acids; Picrotoxin; Potassium; Pyridazines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes | 1987 |
GABAergic regulation of tuberoinfundibular dopaminergic neurons in the male rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Baclofen; Dopamine; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Isonicotinic Acids; Male; Neurons; Osmolar Concentration; Prolactin; Pyridazines; Rats; Rats, Inbred Strains; Seizures | 1994 |
gamma-Aminobutyric acid receptor-mediated regulation of periventricular-hypophysial dopaminergic neurons: possible role in mediating stress- and 5-hydroxytryptamine-induced decreases in neuronal activity.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-MSH; Animals; Baclofen; Dopamine; Hypothalamus, Middle; Male; Organophosphorus Compounds; Pituitary Gland; Pyridazines; Rats; Receptors, GABA-A; Receptors, GABA-B; Serotonin; Stress, Physiological | 1994 |
Long-term GABA treatment elicits supersensitivity of quisqualate-preferring metabotropic glutamate receptor in cultured rat cerebellar neurons.
Topics: Animals; Baclofen; Carbachol; Cells, Cultured; Cerebellum; Drug Tolerance; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neurons; Potassium Chloride; Pyridazines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Glutamate | 1993 |
CGP 35348 blocks noradrenaline-release-inhibiting GABAB receptors in the pig retina, rat vena cava and pithed rat vasculature.
Topics: Animals; Baclofen; Blood Pressure; Blood Vessels; Decerebrate State; Dose-Response Relationship, Drug; In Vitro Techniques; Norepinephrine; Organophosphorus Compounds; Pyridazines; Rats; Receptors, GABA-A; Retina; Swine; Venae Cavae | 1993 |
Effects of GABA receptor antagonists injected spinally on antinociception induced by opioids administered supraspinally in mice.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Baclofen; beta-Endorphin; Dose-Response Relationship, Drug; GABA Antagonists; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morphine; Muscimol; Pain Measurement; Pyridazines; Reaction Time; Receptors, Opioid; Receptors, Opioid, mu | 1996 |
GABA-induced responses in electrophysiologically characterized neurons within the rat rostro-ventrolateral medulla in vitro.
Topics: Animals; Baclofen; Bicuculline; Brain Stem; Electrophysiology; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Heart Conduction System; In Vitro Techniques; Medulla Oblongata; Neurons; Organophosphorus Compounds; Picrotoxin; Pyridazines; Rats; Rats, Wistar; Synapses | 1996 |
Central GABAA and GABAB receptor modulation of basal and stress-induced plasma interleukin-6 levels in mice.
Topics: Animals; Baclofen; Brain; Dizocilpine Maleate; GABA Modulators; Injections, Intraventricular; Interleukin-6; Male; Mice; Mice, Inbred ICR; Muscimol; Oxidopamine; Pyridazines; Receptors, GABA-A; Receptors, GABA-B; Stress, Physiological | 1998 |
GABA(A) and GABA(B) antagonists differentially affect the firing pattern of substantia nigra dopaminergic neurons in vivo.
Topics: Action Potentials; Animals; Baclofen; Bicuculline; Dopamine; Electrophysiology; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Kinetics; Male; Neurons; Phosphinic Acids; Picrotoxin; Propanolamines; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Substantia Nigra | 1999 |
Differential potentiative effects of GABA receptor agonists in the production of antinociception induced by morphine and beta-endorphin administered intrathecally in the mouse.
Topics: Amino Acids; Amino Acids, Neutral; Analgesics; Animals; Baclofen; beta-Endorphin; Drug Synergism; GABA Agonists; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Muscimol; Pyridazines; Receptors, GABA-A; Receptors, GABA-B | 2000 |
Prototypical imidazoline-1 receptor ligand moxonidine activates alpha2-adrenoceptors in bulbospinal neurons of the RVL.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Baclofen; Barium; Benzazepines; Bridged Bicyclo Compounds; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; Glycine Agents; Heptanes; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Kinetics; Ligands; Medulla Oblongata; Neurons; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, Drug; Strychnine | 2000 |
Gamma-aminobutyric acid neuropharmacological investigations on narcosis produced by nitrogen, argon, or nitrous oxide.
Topics: Anesthesia, Inhalation; Animals; Argon; Baclofen; Flumazenil; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Motor Activity; Nitrogen; Nitrous Oxide; Pyridazines; Rats; Rats, Sprague-Dawley | 2003 |
GABAergic modulation of the activity of globus pallidus neurons in primates: in vivo analysis of the functions of GABA receptors and GABA transporters.
Topics: Action Potentials; Animals; Anisoles; Baclofen; Brain Mapping; Enzyme Inhibitors; GABA Agonists; GABA Antagonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Globus Pallidus; Immunohistochemistry; Macaca mulatta; Membrane Transport Modulators; Membrane Transport Proteins; Microdialysis; Microscopy, Immunoelectron; Muscimol; Neurons; Nipecotic Acids; Phosphinic Acids; Propanolamines; Pyridazines; Receptors, GABA | 2005 |
Synaptically released GABA activates both pre- and postsynaptic GABA(B) receptors in the rat globus pallidus.
Topics: Animals; Animals, Newborn; Baclofen; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; In Vitro Techniques; Neural Inhibition; Neurons; Patch-Clamp Techniques; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Synapses; Synaptic Transmission; Time Factors | 2005 |
Regulation of cardiac sympathetic afferent reflex by GABA(A) and GABA(B) receptors in paraventricular nucleus in rats.
Topics: Animals; Baclofen; Bradykinin; Capsaicin; GABA Agonists; GABA Antagonists; Heart; Isonicotinic Acids; Kidney; Male; Neurons, Afferent; Organophosphorus Compounds; Paraventricular Hypothalamic Nucleus; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Reflex; Sensory System Agents; Sympathetic Nervous System; Vigabatrin | 2008 |
Multiple functions of GABA A and GABA B receptors during pattern processing in the zebrafish olfactory bulb.
Topics: Animals; Baclofen; Calcium; Food; GABA Agonists; GABA Antagonists; Neural Pathways; Neurons; Odorants; Olfactory Bulb; Organophosphorus Compounds; Patch-Clamp Techniques; Pyridazines; Receptors, GABA-A; Receptors, GABA-B; Smell; Zebrafish | 2008 |
GABA transporter 1 tunes GABAergic synaptic transmission at output neurons of the mouse neostriatum.
Topics: Action Potentials; Animals; Animals, Newborn; Baclofen; Bicuculline; Electric Impedance; Electric Stimulation; Electrophysiology; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; In Vitro Techniques; Membrane Potentials; Mice; Mice, Inbred C57BL; Neostriatum; Neurons; Nipecotic Acids; Oximes; Patch-Clamp Techniques; Phosphinic Acids; Presynaptic Terminals; Propanolamines; Pyridazines; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Synaptic Transmission; Tetrodotoxin | 2008 |
GABA(A) and GABA(B) receptors of distinct properties affect oppositely the proliferation of mouse embryonic stem cells through synergistic elevation of intracellular Ca(2+).
Topics: Animals; Baclofen; Calcium; Calcium Channels; Cell Differentiation; Cell Movement; Cell Proliferation; Embryonic Stem Cells; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Gene Expression Regulation; Mice; Muscimol; Pluripotent Stem Cells; Pyridazines; Receptors, GABA-A; Receptors, GABA-B; Time Factors | 2010 |
Cortical inhibition reduces information redundancy at presentation of communication sounds in the primary auditory cortex.
Topics: Algorithms; Animal Communication; Animals; Auditory Cortex; Auditory Perception; Baclofen; Brain Mapping; Cerebral Cortex; Discrimination, Psychological; Electrophysiological Phenomena; Extracellular Space; Female; GABA Antagonists; Guinea Pigs; Male; Microinjections; Neurons; Patch-Clamp Techniques; Phosphinic Acids; Propanolamines; Pyridazines; Receptors, GABA-A; Receptors, GABA-B; Vocalization, Animal | 2013 |
GABA in Paraventricular Nucleus Regulates Adipose Afferent Reflex in Rats.
Topics: Adipose Tissue, White; Afferent Pathways; Animals; Baclofen; gamma-Aminobutyric Acid; Isonicotinic Acids; Kidney; Male; Organophosphorus Compounds; Paraventricular Hypothalamic Nucleus; Pyridazines; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Vigabatrin | 2015 |