spermine and glycine
spermine has been researched along with glycine in 107 studies
Research
Studies (107)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (9.35) | 18.7374 |
| 1990's | 79 (73.83) | 18.2507 |
| 2000's | 15 (14.02) | 29.6817 |
| 2010's | 3 (2.80) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Anis, NA; Bukownik, R; Eldefrawi, AT; Eldefrawi, ME; Goodnow, RA; Nakanishi, K; Usherwood, PN | 1 |
| Earnshaw, DJ; Gait, MJ; Holmes, SC; Singh, M; Stetsenko, D; Stolze, K; Williams, D | 1 |
| Molinoff, PB; Powel, RJ; Pullan, LM; Romano, C; Salama, AI; Williams, K | 1 |
| Delivoria-Papadopoulos, M; Mishra, OP | 2 |
| Lerma, J | 1 |
| Canton, H; Colpaert, F; Lehmann, J | 1 |
| Ransom, RW | 1 |
| Hanna, JL; Molinoff, PB; Williams, K | 1 |
| Bennett, MV; McGurk, JF; Zukin, RS | 1 |
| Behr, JP; Daugeras-Bernard, N; Demeneix, BA; Fredriksson, G; Lezoual'ch, F; Loeffler, JP | 1 |
| Paschetto, KA; Pullan, LM; Verticelli, AM | 1 |
| Bednar, DL; Karbon, EW; Maciver, CR | 1 |
| Carter, CJ; Lloyd, KG; Scatton, B; Zivkovic, B | 1 |
| Deschenes, NL; Ransom, RW | 1 |
| Dawson, VL; Dichter, MA; Molinoff, PB; Romano, C; Williams, K | 1 |
| Barthel, F; Behr, JP; Feltz, A; Feltz, P; Loeffler, JP; Sassone-Corsi, P | 1 |
| Johnson, KM; Sacaan, AI | 1 |
| Dudek, S; Joly, M; Lynch, G; Muller, D; Schottler, F; Thibault, O | 1 |
| Behr, JP; Demeneix, B; Loeffler, JP; Perez-Mutul, J | 1 |
| Anderson, P; Davis, BD; Sparling, PF | 1 |
| Brock, TD; Ray, PH | 1 |
| Kvamme, E; Reichelt, KL; Wedege, E | 1 |
| Ariel, M; Grossowicz, N | 1 |
| Wallis, OC | 1 |
| Baudry, M; Marvizón, JC | 3 |
| Ascher, P; Neyton, J; Paoletti, P | 1 |
| Benjamin, R; Conry, RM; Curiel, DT; Kim, M; Lu, D | 1 |
| Blachier, F; Cherbuy, C; Darcy-Vrillon, B; Duée, PH; Hellio, N; M'Rabet-Touil, H; Robert, V | 1 |
| Kato, S; Yokoyama-Kobayashi, M | 1 |
| Fahey, JM; Lindquist, DG; Miller, LG; Pritchard, GA | 1 |
| Williams, K | 1 |
| Arima, T; Kitamura, Y; Nakamura, J; Nomura, Y; Sato, T | 1 |
| Asari, S; Date, I; Furuta, T; Imaoka, T; Miyoshi, Y; Ohmoto, T; Ono, T; Tsuda, M; Yasuda, T | 1 |
| Fahey, JM; Miller, LG | 1 |
| Capaccioli, S; Mini, E; Papucci, L; Quattrone, A; Schiavone, N | 1 |
| Coderre, TJ | 1 |
| Reynolds, IJ | 1 |
| Oblin, A; Schoemaker, H | 1 |
| Chen, DZ; Chen, SH; Katsura, M; Kuriyama, K; Ohkuma, S | 1 |
| Bennett, MV; Friedman, LK; Paupard, MC; Santchi, L; Wang, AP; Zhang, L; Zheng, X; Zukin, RS | 1 |
| Carter, C; Fage, D; Voltz, C | 1 |
| Kamiya, H; Sawada, S; Yamamoto, C | 1 |
| Delivoria-Papadopoulos, M; Goel, R; Mishra, OP; Razdan, B | 1 |
| Foster, AC; Grimwood, S; Struthers, L | 1 |
| Mack, KD; Walzem, R; Zeldis, JB | 1 |
| Bennett, MV; Durand, GM; Zhang, L; Zheng, X; Zukin, RS | 1 |
| Behr, JP; Broker, TR; Chow, LT; Hua, Z; Remy, JS; Staedel, C | 1 |
| Abdel-Taweb, H; Behr, JP; Benoist, C; Demeneix, BA; Seugnet, I | 1 |
| Molinoff, PB; Pritchett, DB; Shen, YM; Williams, K; Zappia, AM | 1 |
| Benveniste, M; Mayer, ML | 1 |
| Capaccioli, S; Di Pasquale, G; Mazzei, T; Mini, E; Quattrone, A | 1 |
| Behr, JP; Loeffler, JP | 1 |
| Flock, S; Houssier, C; Labarbe, R | 2 |
| Berger, ML | 1 |
| Bout, A; Fortunati, E; Scarpa, M; Valerio, D; Zanta, MA | 1 |
| Gilbert, E; Grimwood, S; Hutson, PH; Ragan, CI | 1 |
| Abdallah, B; Behr, JP; Benoist, C; Demeneix, BA; Scherman, D; Schwartz, B | 1 |
| Cariola, M; Kaech, S; Kim, JB; Ralston, E | 1 |
| Casado, M; Lerma, J; López-Guajardo, A; Mellström, B; Naranjo, JR | 1 |
| Mechtler, K; Plank, C; Szoka, FC; Wagner, E | 1 |
| Fukuchi, J; Igarashi, K; Kashiwagi, K; Williams, K | 1 |
| Emi, N; Kanbe, T; Saito, H; Yoshikawa, K; Yoshikawa, Y | 1 |
| Behr, JP; Boussif, O; Zanta, MA | 1 |
| Bahr, A; Behr, JP; Remy, JS; Sola, B; Staedel, C | 1 |
| Bryant, JL; Gallo, RC; Mahan, LC; Peng, B; Rabinovich, P; Thierry, AR | 1 |
| Flock, S; Gilles, R; Houssier, C | 1 |
| Aguerre-Chariol, O; Airiau, M; Boukhnikachvili, T; Lesieur, S; Ollivon, M; Vacus, J | 1 |
| Benigni, A; Boletta, A; Lutz, J; Monaco, L; Remuzzi, G; Soria, MR | 1 |
| Dunlap, DD; Maggi, A; Monaco, L; Soria, MR | 1 |
| Flock, S; Houssier, C | 1 |
| Bonnafous, C; Colombo, S; Lanza, M; Makovec, F; Revel, L | 1 |
| Gabriel, J; Mitchell, WM; Rosenbloom, ST | 1 |
| Date, I; Imaoka, T; Nagatsu, T; Ohmoto, T | 1 |
| Lu, WY; MacDonald, JF; Orser, BA; Xiong, ZG | 1 |
| Kichler, A; Ogris, M; Wagner, E; Zauner, W | 1 |
| Aoki, Y; Horiuchi, A; Karasawa, Y; Kawa, S; Kiyosawa, K | 1 |
| Reynolds, IJ; Sharma, TA | 1 |
| Calderón, F; López-Colomé, AM | 1 |
| Amura, CR; David, SA; Kielian, T; Morrison, DC; Silverstein, R | 1 |
| Doi, T; Imanishi, T; Miyashita, K; Obika, S; Shimoyama, A; Uneda, T; Yu, W | 1 |
| Kim, R; MacDonald, RC; Matsumura, JS; Pearce, WH; Shively, VP | 1 |
| Harvey, SC; Skolnick, P | 1 |
| Castellino, FJ; Galdzicki, Z; Klein, RC | 1 |
| Bertrand, S; Cazalets, JR | 1 |
| Alison, MR; Coutelle, C; Forbes, SJ; Hodgson, HJ; Sarosi, I; Themis, M | 1 |
| Sircar, R | 1 |
| Alison, MR; Coutelle, C; Forbes, SJ; Hodgson, HJ; Kobayashi, T; Shiota, A; Themis, M | 1 |
| Bunney, BS; Shi, WX; Zhang, XX | 1 |
| Herscovici, J; Hofland, H; Jacopin, C; Scherman, D | 1 |
| Hu, GY; Zhang, JM | 1 |
| Gaucheron, J; Santaella, C; Vierling, P | 1 |
| AMOS, H; KEARNS, KE | 1 |
| GOLLAN, F; GRACE, JT; KORY, RC; MENEELY, GR; TYSINGER, DS | 1 |
| Behr, JP; Dalkara, D; Zuber, G | 1 |
| Lamas, M; Lee-Rivera, I; López-Colomé, AM | 1 |
| Dahl, G; Hu, X; Ma, M | 1 |
| Ahmed, OA; Blagbrough, IS; Pourzand, C | 1 |
| de Groot, H; Dehne, N; Li, T; Petrat, F; Rauen, U | 1 |
| Igarashi, K; Kashiwagi, K; Kimura, E; Kizawa, Y; Koike, T; Kusama, T; Kusama-Eguchi, K; Masuko, T; Miyake, M | 1 |
| Brown, BE; Castellino, FJ; Prorok, M; Sheng, Z | 1 |
| Du, W; Dubarry, N; Lane, D; Pasta, F | 1 |
| Hanley, JG; Henley, JM; Jaafari, N | 1 |
| Condon, KH; Ehlers, MD; Hanus, C; Ho, J; Robinson, CG | 1 |
Other Studies
107 other study(ies) available for spermine and glycine
| Article | Year |
|---|---|
Synthesis and binding of [125I2]philanthotoxin-343, [125I2]philanthotoxin-343-lysine, and [125I2]philanthotoxin-343-arginine to rat brain membranes.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Iodine Radioisotopes; Kinetics; Male; Neurotoxins; Polyamines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Spermine; Synaptic Membranes; Wasp Venoms | 1991 |
Novel spermine-amino acid conjugates and basic tripeptides enhance cleavage of the hairpin ribozyme at low magnesium ion concentration.
Topics: Amino Acids; Aminobutyrates; Biochemistry; Magnesium; Nucleic Acid Conformation; Peptides; RNA, Catalytic; Spermine | 2001 |
An antagonist/partial agonist at the polyamine recognition site of the N-methyl-D-aspartate receptor that alters the properties of the glutamate recognition site.
Topics: Animals; Binding Sites; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Piperazines; Polyamines; Rats; Receptors, N-Methyl-D-Aspartate; Spermine | 1992 |
NMDA receptor modification in the fetal guinea pig brain during hypoxia.
Topics: Animals; Brain; Dizocilpine Maleate; Female; Fetal Hypoxia; Glutamates; Glutamic Acid; Glycine; Guinea Pigs; Magnesium; Pregnancy; Receptors, N-Methyl-D-Aspartate; Spermine | 1992 |
Modification of modulatory sites of NMDA receptor in the fetal guinea pig brain during development.
Topics: Animals; Binding Sites; Brain; Dizocilpine Maleate; Gestational Age; Glutamates; Glutamic Acid; Glycine; Guinea Pigs; Magnesium; Receptors, N-Methyl-D-Aspartate; Spermine | 1992 |
Spermine regulates N-methyl-D-aspartate receptor desensitization.
Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Electric Conductivity; Electric Stimulation; Glycine; Membrane Potentials; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Spermine; Spinal Cord | 1992 |
Glutamate and glycine co-activate while polyamines merely modulate the NMDA receptor complex.
Topics: 2-Amino-5-phosphonovalerate; Adrenergic alpha-Antagonists; Animals; Biguanides; Binding, Competitive; Biogenic Polyamines; Biotransformation; Brain; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Kynurenic Acid; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine | 1991 |
Polyamine and ifenprodil interactions with the NMDA receptor's glycine site.
Topics: Animals; Binding Sites; Drug Interactions; Glutamates; Glutamic Acid; Glycine; Male; Piperidines; Polyamines; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine; Statistics as Topic | 1991 |
Developmental changes in the sensitivity of the N-methyl-D-aspartate receptor to polyamines.
Topics: Age Factors; Animals; Animals, Newborn; Cerebral Cortex; Dizocilpine Maleate; Female; Fetus; Glutamates; Glutamic Acid; Glycine; Magnesium; Polyamines; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate; Spermine | 1991 |
Polyamines potentiate responses of N-methyl-D-aspartate receptors expressed in xenopus oocytes.
Topics: Animals; Brain; Female; Glycine; Kinetics; Male; Membrane Potentials; N-Methylaspartate; Oocytes; Poly A; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; RNA; RNA, Messenger; Spermine; Xenopus laevis | 1990 |
Gene transfer into intact vertebrate embryos.
Topics: Animals; Base Sequence; Chick Embryo; Chloramphenicol O-Acetyltransferase; Genetic Techniques; Glycine; Molecular Sequence Data; Plasmids; Spermine; Transfection | 1991 |
Agonist-like character of the (R)-enantiomer of 1-hydroxy-3-amino-pyrrolid-2-one (HA-966).
Topics: Amino Acids; Amino Acids, Cyclic; Animals; Binding, Competitive; Dose-Response Relationship, Drug; Glycine; Kynurenic Acid; Male; Pyrrolidinones; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spermine; Stereoisomerism; Synaptosomes | 1991 |
Opposite effects of spermine and arcaine on responses of N-methyl-D-aspartate receptors expressed in Xenopus oocytes.
Topics: Animals; Biguanides; Glycine; N-Methylaspartate; Oocytes; Polyamines; Receptors, N-Methyl-D-Aspartate; Spermine; Xenopus | 1991 |
Ifenprodil and SL 82.0715 as cerebral antiischemic agents. III. Evidence for antagonistic effects at the polyamine modulatory site within the N-methyl-D-aspartate receptor complex.
Topics: Adrenergic alpha-Antagonists; Animals; Aspartic Acid; Binding Sites; Binding, Competitive; Brain; Cells, Cultured; Drug Interactions; Female; Glycine; Male; N-Methylaspartate; Phencyclidine; Piperidines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spermidine; Spermine; Spinal Cord | 1990 |
Polyamines regulate glycine interaction with the N-methyl-D-aspartate receptor.
Topics: Animals; Cerebral Cortex; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Male; Polyamines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spermidine; Spermine | 1990 |
Characterization of polyamines having agonist, antagonist, and inverse agonist effects at the polyamine recognition site of the NMDA receptor.
Topics: Animals; Binding Sites; Cells, Cultured; Diamines; Dibenzocycloheptenes; Dizocilpine Maleate; Electric Conductivity; Glutamates; Glycine; Hippocampus; Kinetics; Magnesium; Polyamines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spermidine; Spermine; Zinc | 1990 |
Lipopolyamine-mediated transfection allows gene expression studies in primary neuronal cells.
Topics: Amino Acid Sequence; Animals; Cell Differentiation; Cell Survival; Cerebellum; Gene Expression Regulation; Genetic Engineering; Glycine; Molecular Sequence Data; Neurons; Phosphatidylethanolamines; Plasmids; Second Messenger Systems; Spermine; Transfection | 1990 |
Spermine enhances binding to the glycine site associated with the N-methyl-D-aspartate receptor complex.
Topics: Animals; Dibenzocycloheptenes; Dizocilpine Maleate; Glycine; Kinetics; Kynurenic Acid; Magnesium; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spermine | 1989 |
Long-lasting physiological effects of bath applied N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Electric Stimulation; Glycine; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Spermine; Time Factors; Valine | 1989 |
Efficient gene transfer into mammalian primary endocrine cells with lipopolyamine-coated DNA.
Topics: Animals; Cells, Cultured; Chloramphenicol O-Acetyltransferase; Glycine; Kinetics; Liposomes; Phosphatidylethanolamines; Pituitary Gland; Plasmids; Spermine; Swine; Transcription, Genetic; Transfection | 1989 |
Pairing of inosine with adenosine in codon position two in the translation of polyinosinic acid.
Topics: Adenosine; Amino Acids; Bacterial Proteins; Carbon Isotopes; Escherichia coli; Glycine; Inosine; Inosine Nucleotides; Magnesium; Models, Chemical; Nucleic Acid Conformation; Peptide Biosynthesis; Polynucleotides; Protein Biosynthesis; RNA, Messenger; Spectrophotometry, Ultraviolet; Spermine; Streptomycin; Valine | 1973 |
Thermal lysis of bacterial membranes and its prevention by polyamines.
Topics: Amines; Bacteriolysis; Carbon Isotopes; Cell Membrane; Cell Membrane Permeability; Enterococcus faecalis; Glycine; Hot Temperature; Magnesium; Protoplasts; Sarcina; Spermine | 1971 |
Effects of amines on the level of N-acetyl-aspartate and N-acetyl-aspartyl-glutamate in mouse brain tissue slices.
Topics: Acetylcholine; Adenosine; Amines; Amino Acids; Amino Alcohols; Aminobutyrates; Animals; Aspartic Acid; Basal Ganglia; Biogenic Amines; Brain; Caffeine; Cerebellum; Cerebral Cortex; Dipeptides; Dopamine; Edetic Acid; Glutamates; Glycine; Histamine; Medulla Oblongata; Mice; Norepinephrine; Pons; Puromycin; Serotonin; Spermine; Taurine | 1971 |
Effect of spermine on the uptake of amino acids in Micrococcus lysodeikticus.
Topics: Alanine; Amino Acids; Autoanalysis; Azides; Carbon Isotopes; Carrier Proteins; Cell Membrane; Dinitrophenols; Glucose; Glycine; Isoleucine; Leucine; Micrococcus; Polyamines; Protein Binding; Spermidine; Spermine; Temperature; Valine | 1972 |
The effect of pentamidine on ribosomes of the parasitic flagellate Crithidia (Strigomonas) oncopelti.
Topics: Amidines; Carbon Isotopes; Eukaryota; Glycine; Magnesium; Nucleic Acids; Ribosomes; Spermine | 1966 |
Allosteric interactions and modulator requirement for NMDA receptor function.
Topics: Allosteric Regulation; Animals; Brain Chemistry; Dizocilpine Maleate; Glutamic Acid; Glycine; In Vitro Techniques; Ion Channels; Kynurenic Acid; Male; Membranes; Protein Conformation; Rats; Rats, Sprague-Dawley; Receptors, Biogenic Amine; Receptors, N-Methyl-D-Aspartate; Spermine | 1994 |
Glycine-independent and subunit-specific potentiation of NMDA responses by extracellular Mg2+.
Topics: Animals; Barium; Calcium; Cell Line; Drug Synergism; Electric Conductivity; Embryo, Mammalian; Embryo, Nonmammalian; Female; Glycine; Humans; Hydrogen-Ion Concentration; Kidney; Magnesium; Membrane Potentials; Mice; N-Methylaspartate; Oocytes; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Spermine; Xenopus | 1995 |
Optimization of methods to achieve mRNA-mediated transfection of tumor cells in vitro and in vivo employing cationic liposome vectors.
Topics: beta-Galactosidase; Breast Neoplasms; Cation Exchange Resins; Cations; Drug Carriers; Fatty Acids, Monounsaturated; Genes, Reporter; Genetic Therapy; Glycine; Humans; Lipids; Liposomes; Luciferases; Phosphatidylethanolamines; Quaternary Ammonium Compounds; Recombinant Fusion Proteins; RNA, Messenger; Safety; Spermine; Transfection; Tumor Cells, Cultured | 1994 |
Transglutaminase activity in enterocytes isolated from pig jejunum.
Topics: Animals; Arginine; Calcium; Cell Separation; Glutamine; Glycine; Jejunum; Kinetics; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine; Swine; Temperature; Transglutaminases | 1995 |
Recombinant f1 phage-mediated transfection of mammalian cells using lipopolyamine technique.
Topics: 3T3 Cells; Animals; Bacteriophages; CHO Cells; Cricetinae; Glycine; Humans; Mice; Plasmids; Spermine; Transfection | 1994 |
Pregnenolone sulfate potentiation of NMDA-mediated increases in intracellular calcium in cultured chick cortical neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Cells, Cultured; Chick Embryo; Dizocilpine Maleate; Fura-2; Glycine; N-Methylaspartate; Nimodipine; Pregnenolone; Spermine | 1995 |
Pharmacological properties of recombinant N-methyl-D-aspartate (NMDA) receptors containing the epsilon 4 (NR2D) subunit.
Topics: Animals; Glutamic Acid; Glycine; Histamine; Oocytes; Piperidines; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Spermine; Xenopus laevis | 1995 |
Inhibitory effects of pentamidine on N-methyl-D-aspartate (NMDA) receptor/channels in the rat brain.
Topics: Animals; Antiviral Agents; Brain; Calcium Channels; Dizocilpine Maleate; Glycine; Mice; N-Methylaspartate; Nitrendipine; Nitric Oxide; Pentamidine; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Spermine; Xenopus | 1995 |
Preliminary results of gene transfer to central nervous system by continuous injection of DNA-liposome complex.
Topics: Analysis of Variance; Animals; Avian Sarcoma Viruses; beta-Galactosidase; Corpus Striatum; DNA; Drug Carriers; Escherichia coli; Gene Transfer Techniques; Genetic Vectors; Glycine; Immunohistochemistry; Liposomes; Male; Mammals; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Repetitive Sequences, Nucleic Acid; Spermine | 1995 |
Interleukin-1 modulates GABAergic and glutamatergic function in brain.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Brain; Calcium; Cells, Cultured; Chick Embryo; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Humans; Interleukin-1; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Neurons; Recombinant Proteins; Spermine; Tumor Necrosis Factor-alpha | 1994 |
Intracellular enhancement of intact antisense oligonucleotide steady-state levels by cationic lipids.
Topics: Base Sequence; Cations; Cell Line; Cell Membrane; Cell Nucleus; Chromatography, High Pressure Liquid; Cytoplasm; Drug Resistance, Multiple; Fatty Acids, Monounsaturated; Glycine; Humans; Lipids; Molecular Sequence Data; Oligonucleotides, Antisense; Quaternary Ammonium Compounds; Spermine | 1994 |
Potent analgesia induced in rats by combined action at PCP and polyamine recognition sites of the NMDA receptor complex.
Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Behavior, Animal; Binding Sites; Dizocilpine Maleate; Drug Combinations; Drug Synergism; Glycine; Injections, Spinal; Male; Nociceptors; Phencyclidine; Polyamines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spermine | 1993 |
[3H]CGP 39653 binding to the agonist site of the N-methyl-D-aspartate receptor is modulated by Mg2+ and polyamines independently of the arcaine-sensitive polyamine site.
Topics: 2-Amino-5-phosphonovalerate; Animals; Biguanides; Binding Sites; Binding, Competitive; Brain; Cell Membrane; Glycine; Kinetics; Magnesium; Polyamines; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine; Tritium | 1994 |
Complex allosteric modulation of the binding of the NMDA receptor antagonist [3H]CGP39653.
Topics: 2-Amino-5-phosphonovalerate; Allosteric Regulation; Animals; Biguanides; Binding Sites; Glycine; In Vitro Techniques; Kynurenic Acid; Male; Piperidines; Prosencephalon; Putrescine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermine | 1994 |
Presence of N-methyl-D-aspartate (NMDA) receptors in neuroblastoma x glioma hybrid NG108-15 cells-analysis using [45Ca2+]influx and [3H]MK-801 binding as functional measures.
Topics: Calcium Radioisotopes; Cations, Divalent; Dizocilpine Maleate; Glioma; Glutamates; Glutamic Acid; Glycine; Hybrid Cells; N-Methylaspartate; Neuroblastoma; Radioligand Assay; Receptors, N-Methyl-D-Aspartate; Spermine; Tritium | 1994 |
[3H]dizocilpine association kinetics distinguish stimulatory and inhibitory polyamine sites of N-methyl-D-aspartate receptors.
Topics: Animals; Biguanides; Binding Sites; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Kinetics; Male; Piperidines; Polyamines; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermine; Tritium | 1994 |
Spermine potentiation of recombinant N-methyl-D-aspartate receptors is affected by subunit composition.
Topics: Alternative Splicing; Animals; Brain; Gene Expression Regulation, Developmental; Glycine; Membrane Potentials; Oocytes; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; RNA, Messenger; Spermine; Structure-Activity Relationship; Xenopus laevis | 1994 |
Synergism between the NMDA receptor antagonistic effects of ifenprodil and the glycine antagonist, 7-chlorokynurenate, in vivo.
Topics: Animals; Chromatography, High Pressure Liquid; Drug Synergism; Glycine; Injections; Kynurenic Acid; Male; N-Methylaspartate; Neostriatum; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine | 1994 |
NMDA receptor activation by spermine requires glutamate but not glycine.
Topics: Animals; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Kynurenic Acid; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermine | 1993 |
Long-lasting potentiation of synaptic transmission in the Schaffer collateral-commissural pathway of the guinea pig hippocampus by activation of postsynaptic N-methyl-D-aspartate receptor.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electric Stimulation; Evoked Potentials; Glycine; Guinea Pigs; Hippocampus; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neurons; Receptors, N-Methyl-D-Aspartate; Spermine; Synapses; Synaptic Transmission | 1993 |
Modification of NMDA receptor by in vitro lipid peroxidation in fetal guinea pig brain.
Topics: Animals; Brain Chemistry; Dizocilpine Maleate; Female; Glutamates; Glutamic Acid; Glycine; Guinea Pigs; Kinetics; Lipid Peroxidation; Membranes; Neuronal Plasticity; Phospholipids; Pregnancy; Receptors, N-Methyl-D-Aspartate; Spermine | 1993 |
Polyamines modulate [3H]L-689,560 binding to the glycine site of the NMDA receptor from rat brain.
Topics: Aminoquinolines; Animals; Biguanides; Binding, Competitive; Cerebral Cortex; Diamines; Dose-Response Relationship, Drug; Glycine; Hippocampus; Polyamines; Putrescine; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine | 1994 |
Cationic lipid enhances in vitro receptor-mediated transfection.
Topics: Asialoglycoprotein Receptor; Asialoglycoproteins; Binding, Competitive; Carcinoma, Hepatocellular; Cell Line; Glycine; Humans; Kinetics; Liver; Liver Neoplasms; Luciferases; Plasmids; Polylysine; Receptors, Cell Surface; Spermine; Transfection; Tumor Cells, Cultured | 1994 |
Mutagenesis rescues spermine and Zn2+ potentiation of recombinant NMDA receptors.
Topics: Amino Acid Sequence; Animals; Base Sequence; Drug Synergism; Electrophysiology; Female; Glycine; Molecular Sequence Data; Mutagenesis, Site-Directed; N-Methylaspartate; Oocytes; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Spermine; Transfection; Xenopus; Zinc | 1994 |
High-efficiency transfection of primary human keratinocytes with positively charged lipopolyamine:DNA complexes.
Topics: DNA; Dose-Response Relationship, Drug; Glycine; Humans; Infant, Newborn; Keratinocytes; Kinetics; Male; Phosphatidylethanolamines; Polyamines; Spermine; Transfection | 1994 |
Temporal and spatial expression of lipospermine-compacted genes transferred into chick embryos in vivo.
Topics: Animals; Avian Sarcoma Viruses; beta-Galactosidase; Brain; Chick Embryo; DNA; Gene Expression; Gene Transfer Techniques; Genes, Reporter; Glycine; Heart; Kinetics; Luciferases; Microinjections; Myocardium; Plasmids; Promoter Regions, Genetic; Spermine | 1994 |
Sensitivity of the N-methyl-D-aspartate receptor to polyamines is controlled by NR2 subunits.
Topics: Animals; Calcium; Glycine; In Vitro Techniques; Magnesium; Membrane Potentials; Peptide Fragments; Receptors, N-Methyl-D-Aspartate; Spermine; Xenopus laevis | 1994 |
Multiple effects of spermine on N-methyl-D-aspartic acid receptor responses of rat cultured hippocampal neurones.
Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Glycine; Hippocampus; Kinetics; Membrane Potentials; N-Methylaspartate; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Spermine | 1993 |
Cationic lipids improve antisense oligonucleotide uptake and prevent degradation in cultured cells and in human serum.
Topics: 3T3 Cells; Adenocarcinoma; Animals; Base Sequence; Biological Transport; Cell Line; Colonic Neoplasms; Drug Resistance; Fatty Acids, Monounsaturated; Glycine; Humans; Kinetics; Leukemia; Mice; Molecular Sequence Data; Oligonucleotides, Antisense; Quaternary Ammonium Compounds; Spermine; T-Lymphocytes; Time Factors; Tumor Cells, Cultured | 1993 |
Gene transfer into primary and established mammalian cell lines with lipopolyamine-coated DNA.
Topics: Adrenal Medulla; Animals; Brain; Cattle; Cell Line; Cells, Cultured; Culture Techniques; DNA; Drug Carriers; Enkephalins; Gene Expression Regulation; Glycine; Indicators and Reagents; Kinetics; Liposomes; Mammals; Mice; Neurons; Phosphatidylethanolamines; Pituitary Gland; Pituitary Neoplasms; Polyamines; Promoter Regions, Genetic; Protein Kinases; Protein Precursors; Rats; Second Messenger Systems; Spermine; Swine; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1993 |
Osmotic effectors and DNA structure: effect of glycine on precipitation of DNA by multivalent cations.
Topics: Animals; Cations; DNA; Glycine; Models, Molecular; Nucleic Acid Conformation; Nucleic Acid Denaturation; Osmotic Pressure; Poly dA-dT; Spermidine; Spermine; Terbium | 1995 |
On the true affinity of glycine for its binding site at the NMDA receptor complex.
Topics: Algorithms; Animals; Binding Sites; Chromatography, High Pressure Liquid; Computer Simulation; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Male; Models, Theoretical; Radioligand Assay; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spermine; Water | 1995 |
In vitro and in vivo gene transfer to pulmonary cells mediated by cationic liposomes.
Topics: 3T3 Cells; Adenoviridae; Animals; beta-Galactosidase; Bronchi; Cations; Cell Line; Cells, Cultured; Cystic Fibrosis; DNA, Recombinant; Drug Carriers; Female; Gene Expression; Genes, Reporter; Genetic Vectors; Glycine; Humans; Instillation, Drug; Liposomes; Luciferases; Lung; Macaca mulatta; Mice; Mice, Inbred BALB C; Phosphatidylethanolamines; Quaternary Ammonium Compounds; Recombinant Fusion Proteins; Spermine; Trachea; Transfection | 1996 |
Modulation of 45Ca2+ influx into cells stably expressing recombinant human NMDA receptors by ligands acting at distinct recognition sites.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Calcium; Calcium Radioisotopes; Cycloleucine; Dithionitrobenzoic Acid; Dithiothreitol; Excitatory Amino Acid Agonists; Glutamic Acid; Glycine; Humans; Kainic Acid; L Cells; Ligands; Mice; Neurotoxins; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Spermine; Sulfhydryl Reagents | 1996 |
Lipospermine-based gene transfer into the newborn mouse brain is optimized by a low lipospermine/DNA charge ratio.
Topics: Animals; Animals, Newborn; Brain; DNA; Dose-Response Relationship, Drug; Electrochemistry; Female; Gene Transfer Techniques; Glycine; Lipopolysaccharides; Male; Mice; Phosphatidylethanolamines; Spermine; Transfection | 1995 |
Improved lipid-mediated gene transfer into primary cultures of hippocampal neurons.
Topics: Animals; Cation Exchange Resins; Cells, Cultured; DNA; Drug Carriers; Fatty Acids, Monounsaturated; Fluorescent Antibody Technique; Fluorescent Dyes; Glycine; Hippocampus; Immunoglobulin kappa-Chains; Lipids; Mice; Neurons; Plasmids; Quaternary Ammonium Compounds; Rats; Recombinant Proteins; Spermine; Transfection | 1996 |
Dielectric constant and ionic strength effects on DNA precipitation.
Topics: Aminocaproic Acid; Animals; beta-Alanine; Biophysical Phenomena; Biophysics; Cations; Cattle; Chemical Precipitation; DNA; Electrochemistry; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Models, Chemical; Osmolar Concentration; Solubility; Spermine | 1996 |
Functional N-methyl-D-aspartate receptors in clonal rat phaeochromocytoma cells.
Topics: Animals; Base Sequence; Blotting, Northern; Blotting, Western; Calcium; Calcium Channels; Cell Line; Clone Cells; Dithiothreitol; Electrophysiology; Ganglia, Sympathetic; Glutamic Acid; Glycine; Kinetics; Magnesium; Membrane Potentials; Molecular Sequence Data; Nerve Growth Factors; Neurons; Pheochromocytoma; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Spermine | 1996 |
Activation of the complement system by synthetic DNA complexes: a potential barrier for intravenous gene delivery.
Topics: Animals; Cations; Complement Activation; DNA, Recombinant; Fatty Acids, Monounsaturated; Gene Transfer Techniques; Genetic Vectors; Glycine; Humans; Injections, Intravenous; Liposomes; Phosphatidylethanolamines; Phospholipids; Polylysine; Quaternary Ammonium Compounds; Sheep; Spermine | 1996 |
An acidic amino acid in the N-methyl-D-aspartate receptor that is important for spermine stimulation.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Glutamic Acid; Glycine; Hydrogen-Ion Concentration; Macromolecular Substances; Molecular Sequence Data; Mutagenesis, Site-Directed; Receptors, N-Methyl-D-Aspartate; Sensitivity and Specificity; Sequence Homology, Amino Acid; Spermine; Stimulation, Chemical; Structure-Activity Relationship; Xenopus | 1995 |
Folding and aggregation of DNA chains induced by complexation with lipospermine: formation of a nucleosome-like structure and network assembly.
Topics: Animals; Bacteriophage T4; DNA; Fibroblasts; Genetic Vectors; Glycine; Microscopy, Electron; Models, Molecular; Nucleic Acid Conformation; Nucleosomes; Rats; Solutions; Spermine; Time Factors; Transfection | 1996 |
Optimized galenics improve in vitro gene transfer with cationic molecules up to 1000-fold.
Topics: Animals; Blood; Cations; Cells, Cultured; Centrifugation; DNA; Gene Transfer Techniques; Genetic Vectors; Glycine; Humans; Mammals; Mice; Polyethyleneimine; Spermine; Transfection | 1996 |
Lipospermine-mediated gene transfer technique into murine cultured cortical cells.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Culture Media; Cytomegalovirus; DNA, Viral; Embryo, Mammalian; Female; Glycine; Kinetics; Lac Operon; Mice; Mice, Inbred Strains; Neurons; Plasmids; Pregnancy; Promoter Regions, Genetic; Spermine; Transfection; Transgenes | 1997 |
Characterization of liposome-mediated gene delivery: expression, stability and pharmacokinetics of plasmid DNA.
Topics: Animals; beta-Galactosidase; DNA; Gene Expression; Genetic Therapy; Genetic Vectors; Glycine; HeLa Cells; Humans; In Situ Hybridization; Liposomes; Luciferases; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Microscopy, Electron; Phosphatidylethanolamines; Plasmids; Spermine; Transfection; Transgenes | 1997 |
Effects of compensatory solutes on DNA and chromatin structural organization in solution.
Topics: Animals; Cations; Chemical Precipitation; Chickens; Chromatin; DNA; Electrochemistry; Glycine; Histones; In Vitro Techniques; Magnetic Resonance Spectroscopy; Molecular Structure; Osmosis; Rats; Sodium; Solutions; Spermine | 1997 |
Structure of in-serum transfecting DNA-cationic lipid complexes.
Topics: 3T3 Cells; Animals; Cations; DNA; Ethanol; Fetal Blood; Glycine; Lipids; Mice; Microscopy, Electron; Sodium Chloride; Spermine; Transfection; X-Ray Diffraction | 1997 |
Nonviral gene delivery to the rat kidney with polyethylenimine.
Topics: Animals; beta-Galactosidase; Drug Carriers; Fatty Acids, Monounsaturated; Gene Transfer Techniques; Genes, Reporter; Glycine; Kidney; Kidney Tubules, Proximal; Luciferases; Male; Polyethyleneimine; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Spermine; Tissue Distribution; Transfection; Transgenes | 1997 |
Nanoscopic structure of DNA condensed for gene delivery.
Topics: Aluminum Silicates; DNA; Gene Transfer Techniques; Glycine; Microscopy, Atomic Force; Peptides; Plasmids; Polyethyleneimine; Spermine | 1997 |
Effect of glycine on DNA structural transitions induced by multivalent cationic compounds.
Topics: Chemical Precipitation; Circular Dichroism; DNA; Glycine; Light; Scattering, Radiation; Spermidine; Spermine; Terbium | 1997 |
Characterization of a novel putative cognition enhancer mediating facilitation of glycine effect on strychnine-resistant sites coupled to NMDA receptor complex.
Topics: Animals; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Glutamic Acid; Glycine; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Nootropic Agents; Norepinephrine; Pentanoic Acids; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Spermine; Stereoisomerism | 1997 |
Induction of mucosal anti-HIV antibodies by facilitated transfection of airway epithelium with lipospermine/DNA complexes.
Topics: Animals; Bronchi; DNA; Epithelial Cells; Female; Gene Transfer Techniques; Glycine; HIV Antibodies; HIV Envelope Protein gp120; HIV Envelope Protein gp160; HIV Infections; Immunity, Mucosal; Mice; Mice, Inbred BALB C; Models, Molecular; Spermine; Transfection | 1995 |
Significant behavioral recovery in Parkinson's disease model by direct intracerebral gene transfer using continuous injection of a plasmid DNA-liposome complex.
Topics: Animals; Aromatic-L-Amino-Acid Decarboxylases; Bovine papillomavirus 1; Cattle; Disease Models, Animal; Drug Carriers; Female; Fluorescent Antibody Technique, Indirect; Gene Transfer Techniques; Genetic Vectors; Glycine; Injections; Liposomes; Motor Activity; Oxidopamine; Parkinson Disease, Secondary; Plasmids; Rats; Rats, Sprague-Dawley; Spermine; Sympatholytics; Tyrosine 3-Monooxygenase | 1998 |
Multiple sites of action of neomycin, Mg2+ and spermine on the NMDA receptors of rat hippocampal CA1 pyramidal neurones.
Topics: Animals; Binding Sites; Calcium; Cell Line; Cells, Cultured; Evoked Potentials; Glutamic Acid; Glycine; Hippocampus; Humans; Magnesium; N-Methylaspartate; Neomycin; Pyramidal Cells; Rats; Receptors, N-Methyl-D-Aspartate; Spermine; Transfection | 1998 |
Influence of the DNA complexation medium on the transfection efficiency of lipospermine/DNA particles.
Topics: Animals; Cell Line; DNA; Gene Expression; Glycine; Humans; Luciferases; Spermine; Transfection; Tumor Cells, Cultured | 1998 |
Anti-proliferative effects of unmodified antisense oligodeoxynucleotides targeted against c-raf mRNA: use of poly (lysine/serine) copolymers or cationic lipopolyamines.
Topics: Cations; Cell Division; Drug Carriers; Glycine; Humans; Oligonucleotides, Antisense; Pancreatic Neoplasms; Peptides; Pharmaceutic Aids; Polyamines; Polyethylene Glycols; Polylysine; Proto-Oncogene Proteins c-raf; RNA, Messenger; Spermine; Thionucleotides; Tumor Cells, Cultured | 1998 |
Complex polyamine effects on [3H]MDL 105,519 binding to the NMDA receptor glycine site.
Topics: Aminoquinolines; Animals; Binding Sites; Binding, Competitive; Brain; Cell Membrane; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glycine; Indoles; Kynurenic Acid; Polyamines; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine; Tritium | 1998 |
Spermine inhibits [3H]glycine binding at the NMDA receptors from plexiform layers of chick retina.
Topics: Animals; Chickens; Dose-Response Relationship, Drug; Glycine; Receptors, N-Methyl-D-Aspartate; Retina; Spermine; Synaptosomes; Tritium | 1998 |
Lipopolyamines: novel antiendotoxin compounds that reduce mortality in experimental sepsis caused by gram-negative bacteria.
Topics: Animals; Cytokines; Fatty Acids, Monounsaturated; Female; Glycine; Gram-Negative Bacteria; Lipopolysaccharides; Mice; RNA, Messenger; Sepsis; Spermine | 1999 |
Gene transfer mediated by YKS-220 cationic particles: convenient and efficient gene delivery reagent.
Topics: Animals; Cation Exchange Resins; Cations; Cattle; Cell Line; Cricetinae; Culture Media; Evaluation Studies as Topic; Fatty Acids, Monounsaturated; Gene Expression; Gene Transfer Techniques; Glycine; Humans; Indicators and Reagents; Lipids; Luciferases; Particle Size; Phosphatidylethanolamines; Plasmids; Quaternary Ammonium Compounds; Spermine; Transfection | 1999 |
Characterization of vascular gene transfer using a novel cationic lipid.
Topics: Blood Proteins; Cation Exchange Resins; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Drug Carriers; Endothelium, Vascular; Gene Expression; Gene Transfer Techniques; Genes, Reporter; Glycine; Humans; Lipid Metabolism; Lipids; Luciferases; Oleic Acids; Phosphatidylcholines; Plasmids; Recombinant Proteins; Spermine; Transfection; Tumor Necrosis Factor-alpha | 1999 |
Polyamine-like actions of aminoglycosides at recombinant N-methyl-D-aspartate receptors.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Electrophysiology; Glycine; Oocytes; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Spermine; Xenopus laevis | 1999 |
Inhibition of NMDA-induced currents by conantokin-G and conantokin-T in cultured embryonic murine hippocampal neurons.
Topics: Animals; Cells, Cultured; Conotoxins; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Intercellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Mollusk Venoms; N-Methylaspartate; Neurons; Peptides; Receptors, N-Methyl-D-Aspartate; Spermine | 1999 |
Regulation by glycine, Mg2+ and polyamines of the N-methyl-D-aspartate-induced locomotion in the neonatal rat spinal cord in vitro.
Topics: Animals; Biguanides; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Kynurenic Acid; Magnesium; Motor Activity; Motor Neurons; N-Methylaspartate; Polyamines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spermine; Spinal Cord; Synapses | 1999 |
Synergistic growth factors enhance rat liver proliferation and enable retroviral gene transfer via a peripheral vein.
Topics: Animals; Cell Division; Drug Synergism; Fibroblast Growth Factor 10; Fibroblast Growth Factor 7; Fibroblast Growth Factors; Gene Expression; Gene Transfer Techniques; Genetic Vectors; Glycine; Growth Substances; Injections, Intravenous; Liver; Male; Rats; Rats, Wistar; Retroviridae; Spermine; Transduction, Genetic; Triiodothyronine | 2000 |
Developmental maturation of the N-methyl-D-aspartic acid receptor channel complex in postnatal rat brain.
Topics: Age Factors; Animals; Binding, Competitive; Brain; Brain Chemistry; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Male; Phencyclidine; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Spermine; Tritium | 2000 |
Tri-iodothyronine and a deleted form of hepatocyte growth factor act synergistically to enhance liver proliferation and enable in vivo retroviral gene transfer via the peripheral venous system.
Topics: Animals; Cell Division; Genetic Therapy; Genetic Vectors; Glycine; Hepatocyte Growth Factor; Liver; Liver Diseases; Male; Rats; Rats, Wistar; Retroviridae; Spermine; Transfection; Triiodothyronine | 2000 |
Enhancement of NMDA-induced current by the putative NR2B selective antagonist ifenprodil.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Kynurenic Acid; Male; Membrane Potentials; N-Methylaspartate; Organ Culture Techniques; Piperidines; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermine | 2000 |
Synthesis and transfecting properties of a glycosylated polycationic DNA vector.
Topics: Genetic Vectors; Glycine; Glycosylation; HeLa Cells; Humans; Lipid Metabolism; Lipids; Micelles; Polyamines; Polyelectrolytes; Spermine; Structure-Activity Relationship; Transfection | 2001 |
Huperzine A, a nootropic alkaloid, inhibits N-methyl-D-aspartate-induced current in rat dissociated hippocampal neurons.
Topics: Alkaloids; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Animals; Cells, Cultured; Dithiothreitol; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glycine; Hippocampus; Hydrogen-Ion Concentration; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neuroprotective Agents; Nootropic Agents; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sesquiterpenes; Spermine; Zinc | 2001 |
Transfection with fluorinated lipoplexes based on fluorinated analogues of DOTMA, DMRIE and DPPES.
Topics: Cell Line; Cell Survival; Epithelial Cells; Fluorine; Genetic Vectors; Glycine; Humans; Lipids; Liposomes; Molecular Structure; Phosphatidylethanolamines; Quaternary Ammonium Compounds; Spermine; Transfection | 2002 |
INFLUENCE OF BACTERIAL RIBONUCLEIC ACID ON ANIMAL CELLS IN CULTURE. II. PROTAMINE ENHANCEMENT OF RNA UPTAKE.
Topics: Amines; Chick Embryo; Escherichia coli; Glycine; Leucine; Metabolism; Pharmacology; Phosphorus Isotopes; Protamines; Research; RNA; RNA, Bacterial; Spermine; Streptomycin; Tissue Culture Techniques | 1963 |
Hypothermia of 1.5 degree C in dogs followed by survival.
Topics: Animals; Body Temperature; Dogs; Glycine; Hypothermia; Spermine | 1955 |
Intracytoplasmic delivery of anionic proteins.
Topics: Animals; Anions; Cell Line; Cytoplasm; Glycine; Humans; Liposomes; Protein Transport; Proteins; Spermine | 2004 |
Cell-specific expression of N-methyl-D-aspartate receptor subunits in Müller glia and neurons from the chick retina.
Topics: Animals; Blotting, Western; Cells, Cultured; Chick Embryo; Glycine; Isoenzymes; Kynurenic Acid; Neuroglia; Neurons; Radioligand Assay; Receptors, N-Methyl-D-Aspartate; Retina; Reverse Transcriptase Polymerase Chain Reaction; Serine; Spermine; Synaptic Membranes | 2005 |
Conductance of connexin hemichannels segregates with the first transmembrane segment.
Topics: Amino Acid Sequence; Animals; Biophysics; Connexins; Gap Junction alpha-4 Protein; Gap Junction beta-1 Protein; Gap Junctions; Glycine; Ion Channel Gating; Leucine; Membrane Potentials; Molecular Sequence Data; Mutation; Oocytes; Patch-Clamp Techniques; Protein Structure, Tertiary; Recombinant Fusion Proteins; RNA, Messenger; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Spermine; Xenopus | 2006 |
Varying the unsaturation in N4,N9-dioctadecanoyl spermines: nonviral lipopolyamine vectors for more efficient plasmid DNA formulation.
Topics: Cell Line; Cell Line, Tumor; Cell Survival; Cells, Cultured; Chemistry, Pharmaceutical; DNA; Drug Carriers; Electrochemistry; Fatty Acids; Glycine; Humans; Indicators and Reagents; Nanostructures; Particle Size; Plasmids; Skin; Spermine; Tetrazolium Salts; Thiazoles; Transfection | 2006 |
Sodium as the major mediator of NO-induced cell death in cultured hepatocytes.
Topics: Animals; Ascorbic Acid; Calcium; Cell Death; Cell Nucleus; Cell Survival; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Drug Combinations; Free Radical Scavengers; Fructose; Glycine; Hepatocytes; Male; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Rats; Rats, Wistar; Reactive Nitrogen Species; Sodium; Spermine | 2006 |
Differential effects of linear and cyclic polyamines on NMDA receptor activities.
Topics: Animals; Cells, Cultured; Cloning, Molecular; Excitatory Amino Acids; Female; Glycine; Hippocampus; Molecular Conformation; Neuroprotective Agents; Oocytes; Polyamines; Rats; Receptors, N-Methyl-D-Aspartate; Spermine; Xenopus laevis | 2008 |
N-methyl-D-aspartate receptor inhibition by an apolipoprotein E-derived peptide relies on low-density lipoprotein receptor-associated protein.
Topics: Animals; Apolipoproteins E; Binding Sites; Cell Line, Transformed; Cell Membrane; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Glycine; Humans; LDL-Receptor Related Proteins; Membrane Potentials; N-Methylaspartate; Patch-Clamp Techniques; Peptide Fragments; Protein Binding; Receptors, N-Methyl-D-Aspartate; Spermine; Transfection | 2008 |
Improved electrotransformation and decreased antibiotic resistance of the cystic fibrosis pathogen Burkholderia cenocepacia strain J2315.
Topics: Base Sequence; Burkholderia cepacia complex; Culture Media; Cystic Fibrosis; DNA Methylation; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Electroporation; Genes, Bacterial; Glycine; Humans; Microbial Sensitivity Tests; Mutation; Plasmids; Recombination, Genetic; Spermine; Transformation, Genetic | 2010 |
PICK1 mediates transient synaptic expression of GluA2-lacking AMPA receptors during glycine-induced AMPA receptor trafficking.
Topics: Animals; Biotinylation; Calcium; Carrier Proteins; Cells, Cultured; Cytoskeletal Proteins; Disks Large Homolog 4 Protein; Embryo, Mammalian; Endosomes; Gene Expression Regulation; Glycine; GTP-Binding Proteins; Hippocampus; Immunoprecipitation; Intracellular Signaling Peptides and Proteins; Long-Term Potentiation; Membrane Proteins; Microscopy, Confocal; Mutation; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Protein Transport; Rats; Rats, Wistar; Receptors, AMPA; RNA, Small Interfering; Spermine; Synapses; Time Factors; Transfection; Transferrin; Vesicular Transport Proteins | 2012 |
The Angelman syndrome protein Ube3a/E6AP is required for Golgi acidification and surface protein sialylation.
Topics: Analysis of Variance; Angelman Syndrome; Animals; Animals, Newborn; Bacterial Proteins; Cells, Cultured; Cerebral Cortex; Cytoplasmic Structures; Disease Models, Animal; Embryo, Mammalian; Female; Gene Expression Regulation; Glycine; Golgi Apparatus; Green Fluorescent Proteins; HEK293 Cells; Humans; Hydrogen-Ion Concentration; Lectins; Luminescent Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Electron, Transmission; Mutagenesis; N-Acetylneuraminic Acid; Neurons; Protein Transport; RNA, Small Interfering; Spermine; Transfection; Ubiquitin-Protein Ligases; Vesicle-Associated Membrane Protein 2; Viral Proteins | 2013 |