sb 216763 and u 0126
sb 216763 has been researched along with u 0126 in 5 studies
Compound Research Comparison
| Studies (sb 216763) | Trials (sb 216763) | Recent Studies (post-2010) (sb 216763) | Studies (u 0126) | Trials (u 0126) | Recent Studies (post-2010) (u 0126) |
|---|---|---|---|---|---|
| 342 | 0 | 225 | 2,816 | 2 | 1,213 |
Protein Interaction Comparison
| Protein | Taxonomy | sb 216763 (IC50) | u 0126 (IC50) |
|---|---|---|---|
| RAF proto-oncogene serine/threonine-protein kinase | Homo sapiens (human) | 0.29 | |
| Serine/threonine-protein kinase B-raf | Homo sapiens (human) | 0.25 | |
| Amine oxidase [flavin-containing] B | Rattus norvegicus (Norway rat) | 0.07 | |
| Dual specificity mitogen-activated protein kinase kinase 2 | Homo sapiens (human) | 0.2816 | |
| Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens (human) | 0.2529 |
Research
Studies (5)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Beugnet, A; Janmaat, M; Paulin, FE; Proud, CG; Wang, X | 1 |
| Brooks, MM; Cammarata, PR; Neelam, S | 1 |
Other Studies
5 other study(ies) available for sb 216763 and u 0126
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
The selectivity of protein kinase inhibitors: a further update.
Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Evidence that the dephosphorylation of Ser(535) in the epsilon-subunit of eukaryotic initiation factor (eIF) 2B is insufficient for the activation of eIF2B by insulin.
Topics: Aminophenols; Animals; Butadienes; CHO Cells; Chromones; Cricetinae; Enzyme Inhibitors; Eukaryotic Initiation Factor-2B; Glycogen Synthase Kinase 3; Indoles; Insulin; Lithium Chloride; Maleimides; Morpholines; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinases; Protein Subunits; Serine; TOR Serine-Threonine Kinases | 2002 |
Lenticular mitoprotection. Part B: GSK-3β and regulation of mitochondrial permeability transition for lens epithelial cells in atmospheric oxygen.
Topics: Animals; bcl-2-Associated X Protein; bcl-Associated Death Protein; Benzimidazoles; Butadienes; Carbocyanines; Cattle; Cell Hypoxia; Cell Line; Epithelial Cells; Fluorescent Dyes; Gene Expression Regulation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Indoles; Lens, Crystalline; Maleimides; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitogen-Activated Protein Kinases; Nitriles; Oxygen; Phosphorylation; Protein Kinase Inhibitors; Signal Transduction | 2013 |