sb 216763 and serine
sb 216763 has been researched along with serine in 17 studies
Compound Research Comparison
| Studies (sb 216763) | Trials (sb 216763) | Recent Studies (post-2010) (sb 216763) | Studies (serine) | Trials (serine) | Recent Studies (post-2010) (serine) |
|---|---|---|---|---|---|
| 342 | 0 | 225 | 23,914 | 115 | 6,084 |
Protein Interaction Comparison
| Protein | Taxonomy | sb 216763 (IC50) | serine (IC50) |
|---|---|---|---|
| Acetylcholinesterase | Electrophorus electricus (electric eel) | 0.015 | |
| Cholinesterase | Equus caballus (horse) | 0.016 |
Research
Studies (17)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (47.06) | 29.6817 |
| 2010's | 9 (52.94) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Beugnet, A; Janmaat, M; Paulin, FE; Proud, CG; Wang, X | 1 |
| Allgaier, C; Camins, A; Canudas, AM; Garcia de Arriba, S; Jiménez, A; Jordà, EG; Pallàs, M; Verdaguer, E | 1 |
| Kobayashi, H; Maruta, T; Nemoto, T; Satoh, S; Sugano, T; Wada, A; Yanagita, T; Yokoo, H; Yoshikawa, N | 1 |
| Bijur, GN; Gandy, JC; King, TD | 1 |
| Cao, Q; Feng, YJ | 1 |
| Bauchwitz, RP; Chen, S; Jope, RS; Min, WW; Sikorski, C; Yan, Q; Yuskaitis, CJ | 1 |
| Johnson, A | 1 |
| Li, QQ; Lu, L; Shi, J; Wang, J; Wu, P; Xu, CM; Xue, YX; Zhai, HF; Zhu, WL | 1 |
| Barton-Pai, A; Feleder, C; Johnson, A | 1 |
| Chen, NN; Liu, B; Liu, D; Liu, GP; Luo, DJ; Ni, ZF; Wang, JZ; Wang, Q; Wang, X; Yao, XQ; Yin, YY; Zhang, XX | 1 |
| Alessandrini, A; Benedict Cosimi, A; Benichou, G; Colvin, RB; De Haseth, S; Fray, M; Miyajima, M; Williams, WW | 1 |
| Gao, G; Guo, X; Lv, F; Sun, L | 1 |
| Baake, J; Jaeger, A; Kriehuber, R; Weiss, DG | 1 |
| Ahn, SG; Lee, BH; Oh, SH; Park, CH; Yoon, JH | 1 |
| Dong, Z; Du, S; Huang, J; Lei, T; Sun, M; Tong, R; Wang, H; Wang, Y; Yang, J; Yang, Y | 1 |
| Abd-Ellah, A; Krappmann, D; Marienfeld, RB; Möller, P; Voogdt, C | 1 |
| Chen, K; Du, M; Feng, Y; Fu, Q; Liang, P; Lu, J; Wang, W; Ye, C; Zhan, X | 1 |
Other Studies
17 other study(ies) available for sb 216763 and serine
| Article | Year |
|---|---|
Evidence that the dephosphorylation of Ser(535) in the epsilon-subunit of eukaryotic initiation factor (eIF) 2B is insufficient for the activation of eIF2B by insulin.
Topics: Aminophenols; Animals; Butadienes; CHO Cells; Chromones; Cricetinae; Enzyme Inhibitors; Eukaryotic Initiation Factor-2B; Glycogen Synthase Kinase 3; Indoles; Insulin; Lithium Chloride; Maleimides; Morpholines; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinases; Protein Subunits; Serine; TOR Serine-Threonine Kinases | 2002 |
Implication of cyclin-dependent kinase 5 in the neuroprotective properties of lithium.
Topics: Aminophenols; Analysis of Variance; Animals; Animals, Newborn; Apoptosis; Blotting, Western; Caspases; Cell Survival; Cells, Cultured; Cerebellum; Colchicine; Culture Media, Serum-Free; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Indoles; Lithium; Maleimides; MEF2 Transcription Factors; Microscopy, Electron, Transmission; Myogenic Regulatory Factors; Neurons; Neuroprotective Agents; Potassium Deficiency; Rats; Rats, Sprague-Dawley; Serine; Threonine; Time Factors; Transcription Factors | 2005 |
Constitutive activity of glycogen synthase kinase-3beta: positive regulation of steady-state levels of insulin receptor substrates-1 and -2 in adrenal chromaffin cells.
Topics: Acetylcysteine; Adjuvants, Immunologic; Adrenal Glands; Animals; Blotting, Northern; Cattle; Cells, Cultured; Chromaffin Cells; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Gene Expression Regulation; Glycogen Synthase Kinase 3; Indoles; Lactones; Lithium Chloride; Maleimides; Phosphoproteins; Phosphorylation; Proteasome Endopeptidase Complex; Serine; Time Factors | 2006 |
The protein phosphatase-1/inhibitor-2 complex differentially regulates GSK3 dephosphorylation and increases sarcoplasmic/endoplasmic reticulum calcium ATPase 2 levels.
Topics: Animals; Calcium; Cell Line, Tumor; Culture Media, Serum-Free; Endoplasmic Reticulum; Glycogen Synthase Kinase 3; Humans; Indoles; Lithium; Maleimides; Mice; Multiprotein Complexes; Phosphoprotein Phosphatases; Phosphorylation; Potassium Chloride; Protein Phosphatase 1; Proteins; Proto-Oncogene Proteins c-akt; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Serine | 2006 |
[Glycogen synthase kinase-3beta (GSK-3beta) promotes proliferation of ovarian cancer cells in vitro].
Topics: beta Catenin; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Green Fluorescent Proteins; Humans; Indoles; Lithium Chloride; Maleimides; Microscopy, Fluorescence; Ovarian Neoplasms; Phosphorylation; Plasmids; Serine; Time Factors; Transfection | 2006 |
Elevated glycogen synthase kinase-3 activity in Fragile X mice: key metabolic regulator with evidence for treatment potential.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Antimanic Agents; Brain; Citrates; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Exploratory Behavior; Fragile X Mental Retardation Protein; Gene Expression Regulation; Glycogen Synthase Kinase 3; Indoles; Lithium Chloride; Male; Maleimides; Mice; Mice, Knockout; Pyridines; Seizures; Serine; Thiazoles; Urea | 2009 |
TNF-induced activation of pulmonary microvessel endothelial cells: a role for GSK3beta.
Topics: Animals; beta Catenin; Cattle; Cell Nucleus; Endothelial Cells; Enzyme Activation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Indoles; Lung; Maleimides; Microvessels; Phosphorylation; Promoter Regions, Genetic; Protein Kinase C-alpha; Protein Transport; Rats; Serine; Tumor Necrosis Factor-alpha | 2009 |
Glycogen synthase kinase 3beta in the nucleus accumbens core mediates cocaine-induced behavioral sensitization.
Topics: Adjuvants, Immunologic; Analysis of Variance; Animals; Behavior, Addictive; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Indoles; Lithium Chloride; Male; Maleimides; Motor Activity; Nucleus Accumbens; Phosphorylation; Rats; Rats, Sprague-Dawley; Serine; Time Factors | 2009 |
Tumor necrosis factor-α induces increased lung vascular permeability: a role for GSK3α/β.
Topics: Animals; beta Catenin; Biomarkers; Capillary Permeability; Enzyme Activation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Indoles; Lung; Male; Maleimides; Nitric Oxide Synthase Type III; Oxidation-Reduction; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Serine; Thiadiazoles; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine | 2011 |
Glycogen synthase kinase-3β regulates Tyr307 phosphorylation of protein phosphatase-2A via protein tyrosine phosphatase 1B but not Src.
Topics: Androstadienes; Animals; Cyclic AMP Response Element-Binding Protein; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; HEK293 Cells; Humans; Indoles; Maleimides; Mice; Mice, Inbred C57BL; Protein Phosphatase 2; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Rats; RNA, Messenger; Serine; src-Family Kinases; tau Proteins; Transcription, Genetic; Tyrosine; Wortmannin | 2011 |
Dendritic cell maturation occurs through the inhibition of GSK-3β.
Topics: Adaptive Immunity; Animals; Antigen Presentation; B7-1 Antigen; B7-2 Antigen; beta Catenin; Cell Differentiation; Dendritic Cells; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Granulocyte-Macrophage Colony-Stimulating Factor; In Vitro Techniques; Indoles; Interleukin-2; Interleukin-4; Male; Maleimides; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Models, Biological; Phagocytosis; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Serine; Signal Transduction; Substrate Specificity; Tumor Necrosis Factor-alpha | 2011 |
Glycogen synthase kinase 3β (GSK3β) modulates antiviral activity of zinc-finger antiviral protein (ZAP).
Topics: Animals; Carrier Proteins; Gene Library; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; HEK293 Cells; Humans; Indoles; Lentivirus; Lentivirus Infections; Maleimides; Phosphorylation; Rats; RNA-Binding Proteins; RNA, Small Interfering; RNA, Viral; Serine; Threonine | 2012 |
Glycogen synthase kinase-3beta regulates differentiation-induced apoptosis of human neural progenitor cells.
Topics: Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Differentiation; Cell Line; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Indoles; Maleimides; Membrane Glycoproteins; Neural Stem Cells; Protozoan Proteins; Serine; Statistics, Nonparametric; Time Factors; Tubulin | 2013 |
Serine 9 and tyrosine 216 phosphorylation of GSK-3β differentially regulates autophagy in acquired cadmium resistance.
Topics: Aged; Animals; Autophagy; Cadmium; Cell Line, Tumor; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Indoles; Male; Maleimides; Mice; Mice, Inbred C57BL; Phosphorylation; Serine; Tyrosine | 2013 |
Nuclear GSK3β induces DNA double-strand break repair by phosphorylating 53BP1 in glioblastoma.
Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; DNA Breaks, Double-Stranded; DNA Repair; Glioblastoma; Glycogen Synthase Kinase 3 beta; Humans; Indoles; Male; Maleimides; Mice; Mice, Inbred BALB C; Mice, Nude; Phosphorylation; Protein Transport; Radiation, Ionizing; Serine; Survival Rate; Tumor Suppressor p53-Binding Protein 1; Xenograft Model Antitumor Assays | 2018 |
GSK3β modulates NF-κB activation and RelB degradation through site-specific phosphorylation of BCL10.
Topics: Aminophenols; B-Cell CLL-Lymphoma 10 Protein; Cell Line; Glycogen Synthase Kinase 3 beta; Humans; Indoles; Jurkat Cells; Lymphocyte Activation; Maleimides; NF-kappa B; Phosphorylation; Proteolysis; Serine; Signal Transduction; T-Lymphocytes; Transcription Factor RelB | 2018 |
The Regulating Role of SB216763 in Pseudomonas aeruginosa Keratitis.
Topics: Animals; Cornea; Cytokines; Eye Infections, Bacterial; Female; Glycogen Synthase Kinase 3 beta; Humans; Indoles; Inflammation Mediators; Keratitis; Maleimides; Mice, Inbred C57BL; Phosphorylation; Pseudomonas aeruginosa; Pseudomonas Infections; Real-Time Polymerase Chain Reaction; Serine | 2019 |