Compounds > sabinene
Page last updated: 2024-08-22

sabinene and warfarin

sabinene has been researched along with warfarin in 128 studies

Research

Studies (128)

TimeframeStudies, this research(%)All Research%
pre-19904 (3.13)18.7374
1990's16 (12.50)18.2507
2000's40 (31.25)29.6817
2010's48 (37.50)24.3611
2020's20 (15.63)2.80

Authors

AuthorsStudies
Conti, F; Cristalli, G; Giuliani, C; Maggi, F; Papa, F; Sagratini, G; Vittori, S1
Hirose, S; Naganuma, M; Nakajima, K; Nakayama, Y; Someya, T1
Goren, R; Kahan, RS; Monselise, SP; Riov, J1
Hoffmann, A; Merkel, U; Sigusch, H1
Barth, D; Chouchi, D1
Beier, RC; Dillman, A; Hansen, RC; Macias, C; Nigg, HN; Nordby, HE1
Legrum, W; Runkel, M; Tegtmeier, M1
Koshimizu, K; Kuki, W; Murakami, A; Nakamura, Y; Ohigashi, H; Ohto, Y; Takahashi, Y; Yonei, H1
Hara, A; Kakumoto, M; Kawabata, K; Koshimizu, K; Kuki, W; Makita, H; Mori, H; Murakami, A; Ohigashi, H; Satoh, K; Takahashi, Y; Tanaka, T; Yonei, H1
Bourian, M; Legrum, W; Runkel, M; Tegtmeier, M1
Fuhr, U1
Hara, A; Kakumoto, M; Kawabata, K; Koshimizu, K; Kuki, W; Maeda, M; Murakami, A; Odashima, S; Ohigashi, H; Ota, T; Takahashi, Y; Tanaka, T; Yamane, T; Yonei, H1
Boyden, TW; Ford, MA; Sullivan, DM1
el-Shafae, AM; Soliman, AS1
Bartle, WR1
Bourian, M; Freudenstein, J; Krisp, A; Legrum, W; Runkel, M; Tegtmeier, M1
Isobe, M; Koshimizu, K; Miyake, Y; Murakami, A; Ohigashi, H; Sugiyama, Y1
Ikoma, Y; Kawasaki, A; Nakano, M; Nesumi, H; Ogawa, K; Yano, M; Yoshida, T1
Fukuda, K; Guo, LQ; Ohta, T; Yamazoe, Y1
Fukuda, K; Guo, LQ; Ohta, T; Tassaneeyakul, W; Yamazoe, Y1
Fukuda, K; Guo, L; Ohashi, N; Yamazoe, Y; Yoshikawa, M1
Haga, M; Koshimizu, K; Kuki, W; Murakami, A; Ohigashi, H; Sasaki, K; Takahashi, Y; Ueda, N; Wada, K; Yonei, H1
Matsuo, H; Morimoto, S; Ohnishi, A; Ohtani, H; Sawada, Y; Shoyama, Y; Takanaga, H; Yamada, S1
Dugo, G; Dugo, L; Dugo, P; Mondello, L; Stancanelli, R1
Ortega, X; Pérez, LM1
Asberg, A; Molden, E1
Ishihara, M; Miyazawa, M; Tougo, H1
Beiere, RC; Hansen, RC; Nigg, HN; Wagner, AM; Wu, JJ1
Inaba, N; Kuki, W; Kuwahara, S; Murakami, A; Takahashi, Y; Yamane, K1
Castañeda, P; Ortega, X; Perez, LM; Polanco, R1
El-Naggar, ME; Mikhail, MW1
Chen, XG; Hu, ZD; Ju, Y; Wang, SF1
Andrea, A; Andrea, V; Nadia, N; Teresa, RM1
KARIYONE, T; MATSUNO, T1
BERNHARD, RA1
Dugo, G; Dugo, P; Favoino, O; Luppino, R; Mondello, L1
Hara, A; Hirose, Y; Ikemoto, K; Katayama, M; Koshimizu, K; Kuno, T; Mori, H; Murakami, A; Ohigashi, H; Sakata, K; Tanaka, T; Yamada, Y; Yoshida, K; Zheng, Q1
Chen, Z; Lin, L1
Furukawa, H; Ito, C; Itoigawa, M; Ju-ichi, M; Nishino, H; Sakamoto, N; Tokuda, H1
Chinou, E; Chinou, I; Magiatis, P; Melliou, E; Mitaku, S; Skaltsounis, AL1
Ju-Ichi, M1
Miller, EG; Patil, BS; Pike, LM; Walzem, RL; Wang, L; Yu, J1
Agabbio, M; D'hallewin, G; Dore, A; Molinu, MG; Venditti, T1
Ortega, X; Pérez, LM; Velásquez, JC1
Afza, N; Ali, MS; Anwar, MA; Saleem, M1
Hara, A; Hirose, Y; Kitaori, N; Kuno, T; Mori, H; Murakami, A; Oyama, T; Sakata, K; Tanaka, T; Yamada, Y1
Kawabata, K; Murakami, A; Ohigashi, H1
Hayashi, K; Kohno, H; Miyamoto, S; Shin-Ichiroh, Y; Sugie, S; Suzuki, R; Takashima, S; Tanaka, T1
Inada, K; Kakiuchi, S; Kakudo, K; Oda, K; Okuno, Y; Takeda, K; Tanaka, T; Tsutsumi, Y; Utsunomiya, H1
Goto, T; Hirai, S; Kang, MS; Kawada, T; Kuroyanagi, K; Kusudo, T; Ohyama, K; Sasaki, T; Takahashi, N; Yano, M; Yu, R1
Hosotani, K; Kuki, W; Murakami, A; Ohigashi, H1
Fujita, T; Iwaki, M; Kawase, A; Masuda, M; Matsuda, H; Niwa, T; Tomohiro, N1
Katsumata, S; Murakami, A; Ohigashi, H; Song, M; Suzuki, K; Uehara, M1
Konstantopoulou, MA; Mazomenos, BE; Siskos, EP1
Ishigamori-Suzuki, R; Oyama, T; Tanaka, T; Yasui, Y1
Akita, K; Fujii, M; Hirata, T; Hongo, D; Kuroyanagi, M; Ogawa, K; Yanaka, N1
Childers, A; Itoh, K; Kleiner, HE; Li, Y; Prince, M; Yamamoto, M1
Batalhão, JR; Bueno, OC; Cazal, Cde M; da Silva, MF; Domingues, Vde C; Fernandes, JB; Filho, ER; Vieira, PC1
Aldaz, CM; Grand, R; Kleiner-Hancock, HE; Krishnan, P; Li, BD; McLarty, J; Tubbs, J; Windler, D; Yan, KJ1
Aturki, Z; Badjah-Hadj-Ahmed, AY; D'Orazio, G; Fanali, S; Rocco, A; Si-Ahmed, K; Tazerouti, F1
Gorgus, E; Guth, S; Lohr, C; Raquet, N; Schrenk, D1
Ye, XQ; Zhao, XM; Zhu, DY1
Chan, YY; Li, CH; Shen, YC; Wu, TS1
Bali, M; Gill, NS; Muthuraman, A; Sharma, PD; Sood, S1
Adegboyega, P; Clifford, JL; Gill, JN; Kleiner-Hancock, HE; Mathis, JM; Prince, M; Remeika, A; Robbins, D; Shi, R; Syed, Z1
Bonesi, M; de Cindio, B; Loizzo, MR; Menichini, F; Provenzano, E; Tundis, R1
Sahebkar, A1
Chen, HF; Li, YG; Yang, SL; Yang, WL; Yuan, JB; Zhang, WG1
Irie, K; Murakami, A; Sekiguchi, H; Takabayashi, F1
Chu, J; Li, SL; Ye, WC; Yin, ZQ; Zhang, QW1
Arora, PK; Chauhan, A; Muthuraman, A; Peters, A; Puri, KD; Ramesh, M; Rana, A; Sood, S1
Furukawa, Y; Nakajima, M; Okuyama, S; Watanabe, S1
Azuma, J; Hori, H; Inoue, T; Koeduka, T; Munakata, R; Sasaki, K; Sugiyama, A; Tsurumaru, Y; Uto, Y; Yazaki, K1
Bonaccorsi, I; Carnovale, C; Dugo, P; Mondello, L; Russo, M; Sarò, M1
Curini, M; Epifano, F; Ferranti, A; Mandrioli, R; Mercolini, L; Protti, M; Raggi, MA; Sorella, V1
Hutadilok-Towatana, N; Panthong, K; Rukachaisirikul, V; Srisud, Y; Tewtrakul, S; Voravuthikunchai, SP1
Eghbal, M; Imenshahidi, M; Iranshahi, M; Sahebkar, A1
Goto, T; Hirai, S; Kawada, T; Lin, S; Sakamoto, T; Sasaki, T; Takahashi, N; Yano, M; Yu, R1
Chen, HF; Gong, QF; Li, ZH; Luo, LP; Wei, Y; Yang, B; Yang, WL; Yuan, JB1
Epifano, F; Genovese, S; Grenier, D; La, VD; Zhao, L1
Bourgaud, F; Dugrand, A; Duval, T; Froelicher, Y; Hehn, A; Olry, A1
Hu, JH; Li, PL; Liu, MH; Su, WW1
Bachmann, L; Bastos, JK; Braga, GU; Brancini, GT; de Leão, HC; de Menezes, HD; Massola Júnior, NS; Pereira, AC; Wainwright, M1
Ippolito, A; Sanzani, SM; Schena, L1
Masuda, T; Nakamura, M; Suzuki, T; Takagi, M; Tamura, H1
Del Río, JA; Díaz, L; Ortuño, A; Pérez-Gilabert, M1
Okuyama, S1
Ledesma-Escobar, CA; Luque de Castro, MD; Priego-Capote, F1
Bourgaud, F; Costantino, G; Dugrand-Judek, A; Froelicher, Y; Hehn, A; Ollitrault, P; Olry, A1
Beolor, JC; Bicchi, C; Brevard, H; Liberto, E; Masson, J; Rubiolo, P1
Burkina, V; Halsne, R; Ropstad, E; Zamaratskaia, G; Zlabek, V1
Chuang, CW; Huang, SC; Hung, HY; Hwang, TL; Kuo, DH; Kuo, PC; Liao, YR; Shiao, YJ; Wu, TS1
Hasei, T; Imahori, D; Imai, H; Kanayama, S; Kibi, M; Matsumoto, T; Nakano, Y; Takahashi, K; Watanabe, T1
Chan, YY; Hung, HY; Hwang, TL; Kuo, PC; Wu, TS1
Dong, L; Geng, Y; Li, JF; Xu, HY; Yang, HJ; Yu, GH1
Epifano, F; Fiorito, S; Genovese, S; Taddeo, VA1
Gao, X; Liu, K; Liu, Z; Ma, X; Meng, Q; Ning, C; Sun, H; Sun, P; Wang, C; Wang, X1
Awale, S; Balachandran, C; Dibwe, DF; Phrutivorapongkul, A; Sun, S1
Hung, WL; Li, GJ; Rouseff, RL; Wang, Y; Wu, HJ1
Cao, L; Duan, M; Tang, J; Tian, D; Wang, F; Yao, X; Zhang, Y1
Amakura, Y; Fukuda, N; Furukawa, Y; Kanzaki, T; Katoh, M; Kotani, Y; Nakajima, M; Okuyama, S; Sawamoto, A; Tamai, T; Yoshimura, M1
Donia, MS; Ehrlich, A; Farag, MA; Tawfike, AF; Wessjohann, LA1
Dong, R; Fu, T; Huo, X; Liu, K; Ma, X; Meng, Q; Sun, H; Wang, C; Wang, J; Yang, X1
Liu, YP; Luo, XD; Shang, JH; Wu, BF; Yang, XW; Zhao, YL1
Barreto, GE; Bibak, B; Keshavarzi, Z; Sahebkar, A; Sathyapalan, T; Shakeri, F1
Chen, J; Chen, M; Liu, Y; Peng, Z; Shi, M; Wen, H; Xu, J; Yuan, Z; Zhang, H1
Furukawa, Y; Hara, RI; Nakajima, M; Nakaya, M; Okuyama, S; Sawamoto, A1
Cai, X; Huang, D; Lei, Y; Lin, M; Luo, K; Sun, Z; Tan, S; Wang, Y; Xia, X; Yan, J; Zhang, Y1
Furukawa, Y; Hara, RI; Nakajima, M; Okuyama, S; Sawamoto, A; Washimi, YS; Yamaoka, M1
Che, P; Gen, Y; Guo, Y; Hou, E; Liu, Z; Ma, N; Yang, R1
Epifano, F; Fiorito, S; Genovese, S; Kato, Y; Kawai, K; Kawasaki, T; Nabekura, T; Uwai, Y1
Chao, Y; Liu, M; Tao, Y; Wei, M; Yang, Y; Zeng, C; Zhang, D; Zhang, J; Zheng, G1
Furukawa, Y; Nakajima, M; Okuyama, S; Sawamoto, A1
Chen, HF; Li, YG; Meng, Y; Wang, XY; Yang, WL; Yuan, JB1
Furukawa, Y1
Amakura, Y; Fukuda, N; Furukawa, Y; Igase, M; Nakajima, M; Okuyama, S; Sawamoto, A; Tamai, T; Yoshida, T; Yoshimura, M1
Dai, MY; Li, F; Liu, HN; Ma, XF; Wang, YK; Xiao, XR; Zhang, SW; Zhou, ZM1
Jungen, M; Lotz, P; Patz, CD; Schweiggert, R; Steingass, CB1
Epifano, F; Fiorito, S; Genovese, S; Palumbo, L1
Chen, H; Chen, L; Chen, S; Liu, Y; Wang, F1
Angelis, A; Haroutounian, SA; Koulocheri, SD; Mitakou, S; Myrtsi, ED1
Arigò, A; Dugo, P; Mondello, L; Russo, M; Testa Camillo, MR; Zoccali, M1
Funamoto, M; Hamabe-Horiike, T; Hasegawa, K; Katanasaka, Y; Kawaguchi, S; Kawase, Y; Komiyama, M; Miyazaki, Y; Mori, K; Morimoto, T; Murakami, A; Shimizu, K; Shimizu, S; Sunagawa, Y1
Fu, XS; Liu, XD; Liu, ZX; Wang, L; Zhou, RB1
Gao, L; Huang, W; Li, Q; Song, W; Tao, G; Wang, L; Ye, Y; Yin, L; Zhang, Q1
Hu, H; Huang, J; Shi, J; Tong, S; Wang, C; Xu, P; Yang, Y; Zhou, Z1
Cao, X; Pan, S; Shi, K; Xu, Y; Zhang, H; Zhang, P1

Reviews

7 review(s) available for sabinene and warfarin

ArticleYear
Drug interactions with grapefruit juice. Extent, probable mechanism and clinical relevance.
    Drug safety, 1998, Volume: 18, Issue:4

    Topics: Age Factors; Animals; Beverages; Calcium Channel Blockers; Citrus; Coumarins; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Flavonoids; Food-Drug Interactions; Furocoumarins; Herb-Drug Interactions; Humans; Intestine, Small; Male; Mixed Function Oxygenases; Risk Assessment; Sex Factors

1998
[Metabolic interactions with statins].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2001, Jan-20, Volume: 121, Issue:2

    Topics: Anti-Bacterial Agents; Anticholesteremic Agents; Anticoagulants; Azoles; Beverages; Calcium Channel Blockers; Citrus; Cyclosporine; Cytochrome P-450 Enzyme System; Drug Interactions; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunosuppressive Agents; Macrolides; Risk Factors; Warfarin

2001
[Chemical study of citrus plants in the search for cancer chemopreventive agents].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2005, Volume: 125, Issue:3

    Topics: Acridines; Acridones; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Citrus; Coumarins; Flavonoids; Humans; Nuclear Magnetic Resonance, Biomolecular; Quercetin; Structure-Activity Relationship

2005
[Effects of Bioactive Substances from Citrus on the Central Nervous System and Utilization as Food Material].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2015, Volume: 135, Issue:10

    Topics: Animals; Anti-Inflammatory Agents; Brain; Brain Ischemia; Brain-Derived Neurotrophic Factor; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Death; Central Nervous System; Citrus; Coumarins; Cyclooxygenase 2; Disease Models, Animal; Flavones; Food; Hippocampus; Humans; Memory Disorders; Mice; Microglia; Nervous System Diseases; Neurogenesis; Neuroprotective Agents; Phytotherapy; Receptors, N-Methyl-D-Aspartate; Schizophrenia

2015
Prenylated Coumarins of the Genus Citrus: An Overview of the 2006- 2016 Literature Data.
    Current medicinal chemistry, 2018, Volume: 25, Issue:10

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Citrus; Coumarins; Humans; Molecular Structure; Plant Extracts; Prenylation

2018
A review of the pharmacological and therapeutic effects of auraptene.
    BioFactors (Oxford, England), 2019, Volume: 45, Issue:6

    Topics: Aegle; Anti-Inflammatory Agents; Apoptosis; Cell Proliferation; Citrus; Coumarins; Humans; Inflammation; Signal Transduction

2019
[Search for Neuroprotective Compounds -From 4-Methycatechol to Citrus Compounds].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2021, Volume: 141, Issue:1

    Topics: Animals; Catechols; Citrus; Cognitive Dysfunction; Coumarins; Disease Models, Animal; Drug Discovery; Female; Humans; Immunoenzyme Techniques; Male; Mice; Nerve Growth Factor; Neuroprotective Agents; Phytotherapy; Rats

2021

Trials

2 trial(s) available for sabinene and warfarin

ArticleYear
Grapefruit juice inhibits 7-hydroxylation of coumarin in healthy volunteers.
    European journal of clinical pharmacology, 1994, Volume: 46, Issue:2

    Topics: Adult; Analysis of Variance; Beverages; Citrus; Coumarins; Female; Humans; Hydroxylation; Male; Reference Values

1994
Naringenin and interindividual variability in interaction of coumarin with grapefruit juice.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1999, Volume: 51, Issue:4-5

    Topics: Adult; Aryl Hydrocarbon Hydroxylases; Beverages; Citrus; Coumarins; Cross-Over Studies; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Flavanones; Flavonoids; Genotype; Humans; Kinetics; Male; Mixed Function Oxygenases; Scopoletin; Umbelliferones

1999

Other Studies

119 other study(ies) available for sabinene and warfarin

ArticleYear
Chemical differences in volatiles between Melittis melissophyllum L. subsp. melissophyllum and subsp. albida (Guss) P. W. Ball (Lamiaceae) determined by solid-phase microextraction (SPME) coupled with GC/FID and GC/MS.
    Chemistry & biodiversity, 2011, Volume: 8, Issue:2

    Topics: Bicyclic Monoterpenes; Complex Mixtures; Coumarins; Gas Chromatography-Mass Spectrometry; Italy; Lamiaceae; Monoterpenes; Octanols; Oils, Volatile; Phylogeography; Plant Leaves; Polycyclic Sesquiterpenes; Principal Component Analysis; Sesquiterpenes; Solid Phase Microextraction

2011
A study of the phototoxicity of lemon oil.
    Archives of dermatological research, 1985, Volume: 278, Issue:1

    Topics: 5-Methoxypsoralen; Animals; Citrus; Coumarins; Furocoumarins; Guinea Pigs; Methoxsalen; Oils, Volatile; Photosensitivity Disorders; Pigmentation Disorders; Skin

1985
Effect of gamma radiation on the synthesis of scopoletin and scopolin in grapefruit peel in relation to radiation damage.
    Radiation research, 1971, Volume: 45, Issue:2

    Topics: Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Citrus; Coumarins

1971
Rapid identification of some coumarin derivatives in deterpenated citrus peel oil by gas chromatography.
    Journal of chromatography. A, 1994, Jun-24, Volume: 672, Issue:1-2

    Topics: 5-Methoxypsoralen; Chromatography, Gas; Citrus; Coumarins; Furocoumarins; Methoxsalen; Plant Oils

1994
Phototoxic coumarins in limes.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1993, Volume: 31, Issue:5

    Topics: Chromatography, High Pressure Liquid; Citrus; Coumarins; Dermatitis, Phototoxic; Humans

1993
Metabolic and analytical interactions of grapefruit juice and 1,2-benzopyrone (coumarin) in man.
    European journal of clinical pharmacology, 1996, Volume: 50, Issue:3

    Topics: Anticoagulants; Antioxidants; Beverages; Chromatography, High Pressure Liquid; Citrus; Coumarins; Flavanones; Flavonoids; Fluorescence; Food-Drug Interactions; Humans; Male; Umbelliferones

1996
Auraptene, a citrus coumarin, inhibits 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion in ICR mouse skin, possibly through suppression of superoxide generation in leukocytes.
    Japanese journal of cancer research : Gann, 1997, Volume: 88, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Cell Line; Citrus; Coumarins; Female; Flow Cytometry; Fluorescent Dyes; Humans; Leukemia, Promyelocytic, Acute; Leukocytes; Mice; Mice, Inbred ICR; Skin Neoplasms; Superoxides; Tetradecanoylphorbol Acetate; Umbelliferones

1997
Citrus auraptene inhibits chemically induced colonic aberrant crypt foci in male F344 rats.
    Carcinogenesis, 1997, Volume: 18, Issue:11

    Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Citrus; Colonic Neoplasms; Coumarins; Glutathione Transferase; Male; NAD(P)H Dehydrogenase (Quinone); Ornithine Decarboxylase; Precancerous Conditions; Rats; Rats, Inbred F344

1997
The character of inhibition of the metabolism of 1,2-benzopyrone (coumarin) by grapefruit juice in human.
    European journal of clinical pharmacology, 1997, Volume: 53, Issue:3-4

    Topics: Anticoagulants; Beverages; Citrus; Coumarins; Cross-Over Studies; Dose-Response Relationship, Drug; Flavanones; Flavonoids; Humans; Male; Umbelliferones

1997
Citrus auraptene exerts dose-dependent chemopreventive activity in rat large bowel tumorigenesis: the inhibition correlates with suppression of cell proliferation and lipid peroxidation and with induction of phase II drug-metabolizing enzymes.
    Cancer research, 1998, Jun-15, Volume: 58, Issue:12

    Topics: Aldehydes; Animals; Anticarcinogenic Agents; Cell Division; Citrus; Colonic Neoplasms; Coumarins; Enzyme Induction; Glutathione Transferase; Intestinal Neoplasms; Lipid Peroxidation; Male; Malondialdehyde; NAD(P)H Dehydrogenase (Quinone); Neoplasm Proteins; Ornithine Decarboxylase; Polyamines; Rats; Rats, Inbred F344

1998
Grapefruit juice and the response to warfarin.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1998, Aug-01, Volume: 55, Issue:15

    Topics: Aged; Analysis of Variance; Anticoagulants; Beverages; Citrus; Food-Drug Interactions; Humans; Male; Middle Aged; Prothrombin Time; Warfarin

1998
A pyranocoumarin and two alkaloids (one with antispasmodic effect) from Citrus deliciosa.
    Die Pharmazie, 1998, Volume: 53, Issue:9

    Topics: Alkaloids; Animals; Citrus; Coumarins; In Vitro Techniques; Intestines; Magnetic Resonance Spectroscopy; Male; Parasympatholytics; Plant Roots; Rabbits; Spectrophotometry, Ultraviolet

1998
Grapefruit juice can interact with medications.
    Harvard heart letter : from Harvard Medical School, 1999, Volume: 9, Issue:8

    Topics: Beverages; Citrus; Coumarins; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Drug Synergism; Humans; Mixed Function Oxygenases

1999
Grapefruit juice might still be factor in warfarin response.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1999, Apr-01, Volume: 56, Issue:7

    Topics: Anticoagulants; Beverages; Citrus; Food-Drug Interactions; Humans; Male; Middle Aged; Warfarin

1999
Identification of coumarins from lemon fruit (Citrus limon) as inhibitors of in vitro tumor promotion and superoxide and nitric oxide generation.
    Journal of agricultural and food chemistry, 1999, Volume: 47, Issue:8

    Topics: Animals; Antineoplastic Agents; Antioxidants; Cell Line; Citrus; Coumarins; Free Radical Scavengers; Herpesvirus 4, Human; HL-60 Cells; Humans; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Plant Extracts; Recombinant Proteins; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virus Activation

1999
Evaluation of auraptene content in citrus fruits and their products.
    Journal of agricultural and food chemistry, 2000, Volume: 48, Issue:5

    Topics: Anticarcinogenic Agents; Chromatography, High Pressure Liquid; Citrus; Coumarins; Evaluation Studies as Topic; Spectrophotometry, Ultraviolet

2000
Role of furanocoumarin derivatives on grapefruit juice-mediated inhibition of human CYP3A activity.
    Drug metabolism and disposition: the biological fate of chemicals, 2000, Volume: 28, Issue:7

    Topics: Aryl Hydrocarbon Hydroxylases; Beverages; Citrus; Coumarins; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Food-Drug Interactions; Humans; Microsomes, Liver; Oxidoreductases, N-Demethylating

2000
Inhibition selectivity of grapefruit juice components on human cytochromes P450.
    Archives of biochemistry and biophysics, 2000, Jun-15, Volume: 378, Issue:2

    Topics: Aryl Hydrocarbon Hydroxylases; Beverages; Chromatography, High Pressure Liquid; Citrus; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Furocoumarins; Humans; Inhibitory Concentration 50; Kinetics; Liver; Microsomes, Liver; Mixed Function Oxygenases; Polycyclic Sesquiterpenes; Sesquiterpenes; Substrate Specificity; Time Factors

2000
Amounts and variation in grapefruit juice of the main components causing grapefruit-drug interaction.
    Journal of chromatography. B, Biomedical sciences and applications, 2000, May-12, Volume: 741, Issue:2

    Topics: Beverages; Calibration; Chromatography, High Pressure Liquid; Citrus; Coumarins; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Food-Drug Interactions; Mass Spectrometry; Mixed Function Oxygenases; Reproducibility of Results; Substrate Specificity

2000
In vitro absorption and metabolism of a citrus chemopreventive agent, auraptene, and its modifying effects on xenobiotic enzyme activities in mouse livers.
    Nutrition and cancer, 2000, Volume: 36, Issue:2

    Topics: Absorption; Animals; Anticarcinogenic Agents; Biological Availability; Caco-2 Cells; Chemoprevention; Citrus; Coumarins; Cytochrome P-450 Enzyme System; Drug Stability; Enzyme Induction; Glutathione Transferase; Half-Life; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Male; Mice; Permeability; Rats; Structure-Activity Relationship; Xenobiotics

2000
Effect of furanocoumarin derivatives in grapefruit juice on the uptake of vinblastine by Caco-2 cells and on the activity of cytochrome P450 3A4.
    British journal of pharmacology, 2000, Volume: 130, Issue:6

    Topics: 3-O-Methylglucose; 5-Methoxypsoralen; Acetates; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Carbon Radioisotopes; Cell Line; Cell Line, Transformed; Citrus; Coumarins; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Furocoumarins; Humans; Hydroxylation; Magnetic Resonance Spectroscopy; Methoxsalen; Microsomes, Liver; Mixed Function Oxygenases; Phenylalanine; Plant Extracts; Recombinant Proteins; Testosterone; Tritium; Vinblastine

2000
LC-MS for the identification of oxygen heterocyclic compounds in citrus essential oils.
    Journal of pharmaceutical and biomedical analysis, 2000, Volume: 24, Issue:1

    Topics: Chromatography, High Pressure Liquid; Citrus; Coumarins; Flavonoids; Furocoumarins; Mass Spectrometry; Oils, Volatile

2000
Participation of the phosphoinositide metabolism in the hypersensitive response of Citrus limon against Alternaria alternata.
    Biological research, 2001, Volume: 34, Issue:1

    Topics: Alternaria; Caffeine; Calcium; Citrus; Coumarins; Fibrinolytic Agents; Heparin; Inositol 1,4,5-Trisphosphate; Neomycin; Phenylalanine Ammonia-Lyase; Phosphatidylinositols; Phosphodiesterase Inhibitors; Protein Synthesis Inhibitors; Seeds; Signal Transduction

2001
Inhibition of acetylcholinesterase activity by essential oil from Citrus paradisi.
    Natural product letters, 2001, Volume: 15, Issue:3

    Topics: Acetylcholinesterase; Animals; Cattle; Cholinesterase Inhibitors; Citrus; Coumarins; Dose-Response Relationship, Drug; Erythrocytes; Gas Chromatography-Mass Spectrometry; Inhibitory Concentration 50; Kinetics; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Oils; Plants, Medicinal; Polycyclic Sesquiterpenes; Sesquiterpenes; Spectrophotometry, Infrared; United States

2001
Bullous phytophotodermatitis associated with high natural concentrations of furanocoumarins in limes.
    American journal of contact dermatitis : official journal of the American Contact Dermatitis Society, 2002, Volume: 13, Issue:1

    Topics: Child; Citrus; Coumarins; Dermatitis, Phototoxic; Diagnosis, Differential; Emergency Treatment; Hand Dermatoses; Humans; Male; Plants, Toxic

2002
Rapid and convenient method for preparing aurapten-enriched product from hassaku peel oil: implications for cancer-preventive food additives.
    Journal of agricultural and food chemistry, 2002, May-22, Volume: 50, Issue:11

    Topics: Adsorption; Anticarcinogenic Agents; Chromatography, High Pressure Liquid; Citrus; Coumarins; Drug Stability; Food Additives; Fruit; Plant Oils; Seasons

2002
Signal transduction in lemon seedlings in the hypersensitive response against Alternaria alternata: participation of calmodulin, G-protein and protein kinases.
    Biological research, 2002, Volume: 35, Issue:3-4

    Topics: Alternaria; Calmodulin; Cholera Toxin; Citrus; Coumarins; Enzyme Induction; Heterotrimeric GTP-Binding Proteins; Phenylalanine Ammonia-Lyase; Phosphorylation; Phytoalexins; Plant Extracts; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Seeds; Sesquiterpenes; Signal Transduction; Terpenes; Trifluoperazine

2002
Rodenticidal activity of two natural coumarines from ether extract of Citrus bergamia.
    Journal of the Egyptian Society of Parasitology, 1999, Volume: 29, Issue:1

    Topics: 5-Methoxypsoralen; Animals; Anticoagulants; Citrus; Coumarins; Ether; Lethal Dose 50; Methoxsalen; Muridae; Plant Extracts; Rats; Rodent Control; Rodenticides

1999
Separation and determination of coumarins in the root bark of three citrus plants by micellar electrokinetic capillary chromatography.
    Planta medica, 2003, Volume: 69, Issue:5

    Topics: Borates; Buffers; Citrus; Coumarins; Electrophoresis, Capillary; Humans; Phytotherapy; Plant Roots

2003
Analysis of some Italian lemon liquors (limoncello).
    Journal of agricultural and food chemistry, 2003, Aug-13, Volume: 51, Issue:17

    Topics: Alcoholic Beverages; Alcohols; Carbohydrates; Chromatography, High Pressure Liquid; Citrus; Coumarins; Fermentation; Fruit; Furocoumarins; Italy; Oxidation-Reduction; Phenols; Volatilization

2003
Studies on the constituents of orange oil. I. On the structure of auraptene.
    Pharmaceutical bulletin, 1953, Volume: 1, Issue:2

    Topics: Citrus; Coumarins; Fruit; Oils; Plant Oils

1953
Occurrence of coumarin analogues in lemon juice.
    Nature, 1958, Oct-25, Volume: 182, Issue:4643

    Topics: Citrus; Coumarins; Fruit; Organic Chemicals

1958
Comprehensive two-dimensional normal-phase (adsorption)-reversed-phase liquid chromatography.
    Analytical chemistry, 2004, May-01, Volume: 76, Issue:9

    Topics: Adsorption; Chromatography, High Pressure Liquid; Citrus; Coumarins; Furocoumarins; Molecular Structure; Sensitivity and Specificity; Silicon Dioxide

2004
Dietary supplementation of the citrus antioxidant auraptene inhibits N,N-diethylnitrosamine-induced rat hepatocarcinogenesis.
    Oncology, 2004, Volume: 66, Issue:3

    Topics: Animals; Anticarcinogenic Agents; Antioxidants; Apoptosis; Body Weight; Carcinogens; Citrus; Coumarins; Dietary Supplements; Diethylnitrosamine; Liver Neoplasms, Experimental; Male; Organ Size; Rats; Rats, Inbred F344

2004
[Study on coumarin compounds from Exocarpium Citri Grandis].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2004, Volume: 27, Issue:8

    Topics: 5-Methoxypsoralen; Citrus; Coumarins; Fruit; Furocoumarins; Methoxsalen; Molecular Structure; Plants, Medicinal

2004
Antitumor-promoting activity of coumarins from citrus plants.
    Planta medica, 2005, Volume: 71, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Citrus; Coumarins; Inhibitory Concentration 50; Mice; Phytotherapy; Skin Neoplasms

2005
Natural and synthetic 2,2-dimethylpyranocoumarins with antibacterial activity.
    Journal of natural products, 2005, Volume: 68, Issue:1

    Topics: Anti-Bacterial Agents; Citrus; Coumarins; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plants, Medicinal; Structure-Activity Relationship; Zanthoxylum

2005
Antioxidant activity of citrus limonoids, flavonoids, and coumarins.
    Journal of agricultural and food chemistry, 2005, Mar-23, Volume: 53, Issue:6

    Topics: 5-Methoxypsoralen; Animals; Antioxidants; Chromatography, High Pressure Liquid; Citrus; Coumarins; Cricetinae; Flavonoids; Free Radical Scavengers; Limonins; Lipoproteins, LDL; Male; Mesocricetus; Methoxsalen; Oxidation-Reduction

2005
Sodium carbonate treatment induces scoparone accumulation, structural changes, and alkalinization in the albedo of wounded citrus fruits.
    Journal of agricultural and food chemistry, 2005, May-04, Volume: 53, Issue:9

    Topics: Carbonates; Citrus; Coumarins; Fruit; Hydrogen-Ion Concentration; Microscopy, Electron, Scanning; Penicillium; Plant Diseases

2005
IP3 production in the hypersensitive response of lemon seedlings against Alternaria alternata involves active protein tyrosine kinases but not a G-protein.
    Biological research, 2005, Volume: 38, Issue:1

    Topics: Alternaria; Calmodulin; Cholera Toxin; Citrus; Coumarins; Enzyme Induction; Enzyme Inhibitors; GTP-Binding Proteins; Inositol 1,4,5-Trisphosphate; Intercellular Signaling Peptides and Proteins; Peptides; Phenols; Protein-Tyrosine Kinases; Seedlings; Signal Transduction; Wasp Venoms

2005
Aromatic constituents from fruit peels of Citrus reticulata.
    Natural product research, 2005, Volume: 19, Issue:6

    Topics: Benzaldehydes; Citrus; Coumarins; Magnetic Resonance Spectroscopy

2005
Suppression of beta-catenin mutation by dietary exposure of auraptene, a citrus antioxidant, in N,N-diethylnitrosamine-induced hepatocellular carcinomas in rats.
    Oncology reports, 2005, Volume: 14, Issue:2

    Topics: Animals; Antioxidants; beta Catenin; Carcinoma, Hepatocellular; Citrus; Coumarins; Cytoskeletal Proteins; Diethylnitrosamine; DNA Mutational Analysis; DNA, Neoplasm; Immunohistochemistry; Liver Neoplasms; Male; Mutation; Rats; Rats, Inbred F344; Trans-Activators

2005
Citrus auraptene targets translation of MMP-7 (matrilysin) via ERK1/2-dependent and mTOR-independent mechanism.
    FEBS letters, 2006, Oct-02, Volume: 580, Issue:22

    Topics: Antibiotics, Antineoplastic; Cell Line, Tumor; Citrus; Coumarins; Enzyme Precursors; Eukaryotic Initiation Factors; Humans; MAP Kinase Signaling System; Metalloendopeptidases; Neoplasm Proteins; Phosphorylation; Protein Biosynthesis; Protein Kinases; Protein Processing, Post-Translational; RNA, Messenger; RNA, Small Interfering; Sirolimus; TOR Serine-Threonine Kinases; Transfection

2006
Citrus auraptene suppresses azoxymethane-induced colonic preneoplastic lesions in C57BL/KsJ-db/db mice.
    Nutrition and cancer, 2007, Volume: 58, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Azoxymethane; Carcinogens; Cell Division; Citrus; Colonic Neoplasms; Coumarins; Diet; Female; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Phenotype; Precancerous Conditions; Random Allocation

2007
Citrus auraptene reduces Helicobacter pylori colonization of glandular stomach lesions in Mongolian gerbils.
    Journal of oleo science, 2007, Volume: 56, Issue:5

    Topics: Animals; Antibodies, Bacterial; Body Weight; Citrus; Coumarins; Gerbillinae; Helicobacter Infections; Helicobacter pylori; Male; Microbial Viability; Stomach Diseases

2007
Citrus auraptene acts as an agonist for PPARs and enhances adiponectin production and MCP-1 reduction in 3T3-L1 adipocytes.
    Biochemical and biophysical research communications, 2008, Feb-01, Volume: 366, Issue:1

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Chemokine CCL2; Citrus; Coumarins; Dose-Response Relationship, Drug; Mice; Peroxisome Proliferator-Activated Receptors; Plant Extracts

2008
Metabolism and absorption of auraptene (7-geranyloxylcoumarin) in male SD rats: comparison with 7-ethoxycoumarin.
    Nutrition and cancer, 2008, Volume: 60, Issue:3

    Topics: Animals; Anticarcinogenic Agents; Biological Availability; Chemoprevention; Citrus; Coumarins; Half-Life; Intestinal Absorption; Kidney; Liver; Male; Organ Specificity; Random Allocation; Rats; Rats, Sprague-Dawley; Xenobiotics

2008
Comparative evaluation of 12 immature citrus fruit extracts for the inhibition of cytochrome P450 isoform activities.
    Biological & pharmaceutical bulletin, 2008, Volume: 31, Issue:5

    Topics: Anti-Allergic Agents; Chromatography, High Pressure Liquid; Citrus; Coumarins; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Flavonoids; Fruit; Humans; Isoenzymes; Microsomes, Liver; Plant Extracts; Species Specificity

2008
Citrus nobiletin suppresses bone loss in ovariectomized ddY mice and collagen-induced arthritis in DBA/1J mice: possible involvement of receptor activator of NF-kappaB ligand (RANKL)-induced osteoclastogenesis regulation.
    BioFactors (Oxford, England), 2007, Volume: 30, Issue:3

    Topics: Animals; Antioxidants; Arthritis, Experimental; Benzyl Alcohols; Blotting, Western; Bone Density; Bone Resorption; Cell Line; Citrus; Coumarins; Female; Flavones; Isothiocyanates; Mice; Mice, Inbred DBA; Molecular Structure; Osteogenesis; Ovariectomy; RANK Ligand; Sesquiterpenes; Terpenes

2007
Isolation and identification of insecticidal components from Citrus aurantium fruit peel extract.
    Journal of agricultural and food chemistry, 2008, Jul-23, Volume: 56, Issue:14

    Topics: 5-Methoxypsoralen; Animals; Chemical Fractionation; Citrus; Coumarins; Fruit; Furocoumarins; Insecticides; Methoxsalen; Tephritidae

2008
Citrus compounds inhibit inflammation- and obesity-related colon carcinogenesis in mice.
    Nutrition and cancer, 2008, Volume: 60 Suppl 1

    Topics: Animals; Azoxymethane; Citrus; Colitis; Colonic Neoplasms; Coumarins; Cyclooxygenase 2; Interleukin-1beta; Mice; NF-kappa B; Nitric Oxide Synthase Type II; Obesity; Precancerous Conditions; Tumor Necrosis Factor-alpha

2008
Identification and physiological evaluation of the components from citrus fruits as potential drugs for anti-corpulence and anticancer.
    Bioorganic & medicinal chemistry, 2009, Jan-01, Volume: 17, Issue:1

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Anti-Obesity Agents; Antineoplastic Agents; Cell Line, Tumor; Citrus; Coumarins; Drug Evaluation, Preclinical; Flavones; Humans; Mice

2009
Comparison of citrus coumarins on carcinogen-detoxifying enzymes in Nrf2 knockout mice.
    Toxicology letters, 2009, Mar-28, Volume: 185, Issue:3

    Topics: Animals; Anticarcinogenic Agents; Antioxidants; Basic-Leucine Zipper Transcription Factors; Cell Line, Tumor; Citrus; Coumarins; Cytosol; Female; Glutathione Transferase; Green Fluorescent Proteins; Humans; Liver; Male; Mice; Mice, Knockout; NAD(P)H Dehydrogenase (Quinone); NADPH Dehydrogenase; Pyrazines; Response Elements; Thiones; Thiophenes; Transfection

2009
Isolation of xanthyletin, an inhibitor of ants' symbiotic fungus, by high-speed counter-current chromatography.
    Journal of chromatography. A, 2009, May-08, Volume: 1216, Issue:19

    Topics: Animals; Antifungal Agents; Ants; Basidiomycota; Citrus; Citrus sinensis; Coumarins; Countercurrent Distribution; Plant Extracts; Plant Roots; Solvents; Symbiosis

2009
Citrus auraptene suppresses cyclin D1 and significantly delays N-methyl nitrosourea induced mammary carcinogenesis in female Sprague-Dawley rats.
    BMC cancer, 2009, Jul-29, Volume: 9

    Topics: Animals; Anticarcinogenic Agents; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Citrus; Coloring Agents; Coumarins; Cyclin D1; Female; Formazans; Humans; Methylnitrosourea; Rats; Rats, Sprague-Dawley

2009
Analysis of hesperetin enantiomers in human urine after ingestion of blood orange juice by using nano-liquid chromatography.
    Journal of pharmaceutical and biomedical analysis, 2010, Jan-05, Volume: 51, Issue:1

    Topics: Chromatography, Liquid; Citrus; Coumarins; Hesperidin; Humans; Male; Stereoisomerism

2010
Limettin and furocoumarins in beverages containing citrus juices or extracts.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2010, Volume: 48, Issue:1

    Topics: Beverages; Chromatography, High Pressure Liquid; Citrus; Citrus aurantiifolia; Citrus paradisi; Coumarins; Diet; Furocoumarins; Plant Extracts; Plant Oils

2010
[Isolation and identification of chemical constituents from peels of Citrus changshan-huyou Y.B. Chang].
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2009, Oct-18, Volume: 41, Issue:5

    Topics: Chromatography; Citrus; Coumarins; Fruit; Hydroxybenzoates; Phenols; Sitosterols

2009
Anti-inflammatory principles from the stem and root barks of Citrus medica.
    Chemical & pharmaceutical bulletin, 2010, Volume: 58, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Cell Line; Citrus; Coumarins; Microglia; Molecular Structure; Nitric Oxide; Plant Bark; Plant Roots

2010
Role of 7,8-dimethoxycoumarin in anti-secretary and anti-inflammatory action on pyloric ligation-induced gastritis in rats.
    Journal of Asian natural products research, 2010, Volume: 12, Issue:7

    Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Citrus; Coumarins; Gastritis; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Omeprazole; Pylorus; Rats; Rats, Wistar

2010
Effects of ATRA combined with citrus and ginger-derived compounds in human SCC xenografts.
    BMC cancer, 2010, Jul-26, Volume: 10

    Topics: Animals; Antineoplastic Agents; Benzyl Alcohols; Blotting, Western; Carcinoma, Squamous Cell; Citrus; Coumarins; Drug Synergism; Drug Therapy, Combination; Female; Humans; Lipopolysaccharides; Luciferases; Male; Mice; Mice, SCID; NF-kappa B; Plant Extracts; Skin Neoplasms; Tretinoin; Tumor Cells, Cultured; Xenograft Model Antitumor Assays; Zingiber officinale

2010
In vitro photo-induced cytotoxic activity of Citrus bergamia and C. medica L. cv. Diamante peel essential oils and identified active coumarins.
    Pharmaceutical biology, 2010, Volume: 48, Issue:9

    Topics: 5-Methoxypsoralen; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Citrus; Coumarins; Drug Discovery; Drug Evaluation, Preclinical; Gas Chromatography-Mass Spectrometry; Humans; Inhibitory Concentration 50; Melanoma; Melanoma, Amelanotic; Methoxsalen; Oils, Volatile; Photochemotherapy; Phytotherapy; Time Factors; Ultraviolet Rays

2010
Potential benefits of supplementation with auraptene in cystic fibrosis.
    Clinical nutrition (Edinburgh, Scotland), 2011, Volume: 30, Issue:2

    Topics: Anti-Inflammatory Agents; Citrus; Coumarins; Cystic Fibrosis; Humans; Peroxisome Proliferator-Activated Receptors

2011
Simultaneous quantification of polymethoxylated flavones and coumarins in Fructus aurantii and Fructus aurantii immaturus using HPLC-ESI-MS/MS.
    Journal of pharmaceutical and biomedical analysis, 2012, Feb-05, Volume: 59

    Topics: Chromatography, High Pressure Liquid; Citrus; Coumarins; Drugs, Chinese Herbal; Flavones; Fruit; Limit of Detection; Molecular Structure; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2012
Auraptene attenuates gastritis via reduction of Helicobacter pylori colonization and pro-inflammatory mediator production in C57BL/6 mice.
    Journal of medicinal food, 2012, Volume: 15, Issue:7

    Topics: Animals; Anti-Bacterial Agents; Citrus; Coumarins; Female; Gastric Mucosa; Gastritis; Helicobacter pylori; Inflammation; Inflammation Mediators; Interleukin-1beta; Macrophage Migration-Inhibitory Factors; Mice; Mice, Inbred C57BL; Phytotherapy; Plant Extracts; Tumor Necrosis Factor-alpha

2012
Simultaneous quantification of coumarins, flavonoids and limonoids in Fructus Citri Sarcodactylis by high performance liquid chromatography coupled with diode array detector.
    Journal of pharmaceutical and biomedical analysis, 2012, Volume: 66

    Topics: Calibration; Chromatography, High Pressure Liquid; Citrus; Coumarins; Flavonoids; Limit of Detection; Limonins; Quality Control; Reproducibility of Results; Sensitivity and Specificity; Time Factors

2012
Therapeutic potential of 7,8-dimethoxycoumarin on cisplatin- and ischemia/reperfusion injury-induced acute renal failure in rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 2012, Volume: 385, Issue:7

    Topics: Acute Kidney Injury; Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Antioxidants; Cisplatin; Citrus; Coumarins; Electron Transport Complex IV; Male; Mitochondria; Plant Extracts; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Thiobarbituric Acid Reactive Substances

2012
Neurotrophic effect of citrus auraptene: neuritogenic activity in PC12 cells.
    International journal of molecular sciences, 2012, Volume: 13, Issue:5

    Topics: Animals; Cells, Cultured; Citrus; Coumarins; Enzyme Activation; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurites; Neurogenesis; Neurons; PC12 Cells; Rats; Rats, Wistar

2012
Characterization of coumarin-specific prenyltransferase activities in Citrus limon peel.
    Bioscience, biotechnology, and biochemistry, 2012, Volume: 76, Issue:7

    Topics: Cations, Divalent; Chromatography, High Pressure Liquid; Citrus; Coumarins; Dimethylallyltranstransferase; Diphosphates; Diterpenes; Furocoumarins; Geranyltranstransferase; Humans; Kinetics; Microsomes; Plant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity

2012
Multidimensional liquid chromatography for the determination of chiral coumarins and furocoumarins in Citrus essential oils.
    Journal of separation science, 2012, Volume: 35, Issue:14

    Topics: Chromatography, Liquid; Citrus; Coumarins; Furocoumarins; Oils, Volatile; Plant Oils; Stereoisomerism

2012
Quantitative evaluation of auraptene and umbelliferone, chemopreventive coumarins in citrus fruits, by HPLC-UV-FL-MS.
    Journal of agricultural and food chemistry, 2013, Feb-27, Volume: 61, Issue:8

    Topics: Chromatography, High Pressure Liquid; Citrus; Coumarins; Fruit; Mass Spectrometry; Plant Extracts; Umbelliferones

2013
Benzene, coumarin and quinolinone derivatives from roots of Citrus hystrix.
    Phytochemistry, 2013, Volume: 88

    Topics: Anti-Bacterial Agents; Anti-HIV Agents; Antioxidants; Bacteria; Benzene; Cells, Cultured; Citrus; Coumarins; HIV; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Plant Roots; Quinolones

2013
Hypotensive activity of auraptene, a monoterpene coumarin from Citrus spp.
    Pharmaceutical biology, 2013, Volume: 51, Issue:5

    Topics: Animals; Antihypertensive Agents; Arterial Pressure; Citrus; Coumarins; Dose-Response Relationship, Drug; Heart Rate; Injections, Intravenous; Male; Nifedipine; Rats; Rats, Wistar

2013
Auraptene suppresses inflammatory responses in activated RAW264 macrophages by inhibiting p38 mitogen-activated protein kinase activation.
    Molecular nutrition & food research, 2013, Volume: 57, Issue:7

    Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue; Animals; Anti-Inflammatory Agents; Cell Line, Tumor; Chemokine CCL2; Citrus; Coculture Techniques; Coumarins; Culture Media, Conditioned; Fruit; Inflammation; Insulin Resistance; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Obesity; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plant Extracts; Tumor Necrosis Factor-alpha

2013
[Determination of the active constituents in aurantii fructus from Jiangxi province at different harvest time by HPLC].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2013, Volume: 36, Issue:1

    Topics: Chromatography, High Pressure Liquid; Citrus; Coumarins; Flavones; Fruit; Seasons; Synephrine

2013
Anti-inflammatory and wound healing potential of citrus auraptene.
    Journal of medicinal food, 2013, Volume: 16, Issue:10

    Topics: Aggregatibacter actinomycetemcomitans; Anti-Inflammatory Agents; Cell Line; Citrus; Coumarins; Cytokines; Gingivitis; Humans; Macrophages; Plant Extracts; Wound Healing

2013
Coumarin and furanocoumarin quantitation in citrus peel via ultraperformance liquid chromatography coupled with mass spectrometry (UPLC-MS).
    Journal of agricultural and food chemistry, 2013, Nov-13, Volume: 61, Issue:45

    Topics: Chromatography, High Pressure Liquid; Citrus; Coumarins; Fruit; Furocoumarins; Mass Spectrometry; Plant Extracts

2013
Systematic chemical profiling of Citrus grandis 'Tomentosa' by ultra-fast liquid chromatography/diode-array detector/quadrupole time-of-flight tandem mass spectrometry.
    Journal of pharmaceutical and biomedical analysis, 2014, Volume: 90

    Topics: Chromatography, High Pressure Liquid; Citrus; Coumarins; Drugs, Chinese Herbal; Flavonoids; Fruit; Quality Control; Tandem Mass Spectrometry

2014
Furocoumarins and coumarins photoinactivate Colletotrichum acutatum and Aspergillus nidulans fungi under solar radiation.
    Journal of photochemistry and photobiology. B, Biology, 2014, Feb-05, Volume: 131

    Topics: Antifungal Agents; Aspergillus nidulans; Citrus; Colletotrichum; Coumarins; Furocoumarins; Methoxsalen; Molecular Structure; Photosensitizing Agents; Plant Leaves; Spores, Fungal; Sunlight

2014
Effectiveness of phenolic compounds against citrus green mould.
    Molecules (Basel, Switzerland), 2014, Aug-18, Volume: 19, Issue:8

    Topics: Citrus; Coumarins; Fruit; Fungicides, Industrial; Microbial Sensitivity Tests; Penicillium; Phenols; Plant Diseases; Quercetin; Scopoletin

2014
Stimulation of phosphorylation of ERK and CREB by phellopterin and auraptene isolated from Citrusjunos.
    Natural product communications, 2014, Volume: 9, Issue:10

    Topics: Caffeic Acids; Cell Line, Tumor; Citrus; Coumarins; Cyclic AMP Response Element-Binding Protein; Extracellular Signal-Regulated MAP Kinases; Humans; Phosphorylation; Thymol

2014
Involvement of an extracellular fungus laccase in the flavonoid metabolism in Citrus fruits inoculated with Alternaria alternata.
    Plant physiology and biochemistry : PPB, 2015, Volume: 89

    Topics: Alternaria; Citrus; Coumarins; Flavonoids; Fruit; Laccase; Plant Diseases

2015
Characterization of lemon (Citrus limon) polar extract by liquid chromatography-tandem mass spectrometry in high resolution mode.
    Journal of mass spectrometry : JMS, 2015, Volume: 50, Issue:11

    Topics: Amino Acids; Carbohydrates; Carboxylic Acids; Chromatography, Liquid; Citrus; Coumarins; Flavonoids; Hydroxybenzoates; Plant Extracts; Tandem Mass Spectrometry

2015
The Distribution of Coumarins and Furanocoumarins in Citrus Species Closely Matches Citrus Phylogeny and Reflects the Organization of Biosynthetic Pathways.
    PloS one, 2015, Volume: 10, Issue:11

    Topics: Chromatography, High Pressure Liquid; Citrus; Coumarins; Fruit; Furocoumarins; Mass Spectrometry; Phylogeny; Principal Component Analysis

2015
Oxygenated heterocyclic compounds to differentiate Citrus spp. essential oils through metabolomic strategies.
    Food chemistry, 2016, Sep-01, Volume: 206

    Topics: Chromatography, Gas; Citrus; Coumarins; Flavonoids; Furocoumarins; Heterocyclic Compounds; Metabolomics; Multivariate Analysis; Oils, Volatile; Oxygen; Plant Extracts; Sensitivity and Specificity

2016
In vitro effects of the citrus flavonoids diosmin, naringenin and naringin on the hepatic drug-metabolizing CYP3A enzyme in human, pig, mouse and fish.
    Biochemical pharmacology, 2016, 06-15, Volume: 110-111

    Topics: Animals; Citrus; Coumarins; Cytochrome P-450 CYP3A; Diosmin; Enzyme Inhibitors; Female; Flavanones; Gene Expression; Humans; Hydrolysis; Kinetics; Liver; Male; Mice; Mice, Inbred ICR; Microsomes, Liver; Oncorhynchus mykiss; Species Specificity; Swine

2016
Anti-Inflammatory and Neuroprotective Constituents from the Peels of Citrus grandis.
    Molecules (Basel, Switzerland), 2017, Jun-09, Volume: 22, Issue:6

    Topics: Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents; Cell Death; Cerebral Cortex; Citrus; Complex Mixtures; Coumarins; Flavonoids; Fruit; Humans; Leukocyte Elastase; Lignans; Neurons; Neuroprotective Agents; Neutrophils; Peptide Fragments; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Steroids; Superoxides; Triterpenes; Waste Products

2017
Structures of antimutagenic constituents in the peels of Citrus limon.
    Journal of natural medicines, 2017, Volume: 71, Issue:4

    Topics: Antimutagenic Agents; Citrus; Coumarins; Furocoumarins; Plant Extracts

2017
Constituents of the Fruits of Citrus medica L. var. sarcodactylis and the Effect of 6,7-Dimethoxy-coumarin on Superoxide Anion Formation and Elastase Release.
    Molecules (Basel, Switzerland), 2017, Sep-01, Volume: 22, Issue:9

    Topics: Adult; Carbon-13 Magnetic Resonance Spectroscopy; Citrus; Coumarins; Fruit; Humans; Neutrophils; Pancreatic Elastase; Plant Extracts; Proton Magnetic Resonance Spectroscopy; Superoxides; Young Adult

2017
[Analysis of chemical constituents from Citrus aurantium by UHPLC-LTQ-Orbitrap-MS/MS].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2016, Volume: 41, Issue:18

    Topics: Alkaloids; Chromatography, High Pressure Liquid; Citrus; Coumarins; Drugs, Chinese Herbal; Flavonoids; Limonins; Phytochemicals; Tandem Mass Spectrometry

2016
Hepatoprotection of auraptene from peels of citrus fruits against thioacetamide-induced hepatic fibrosis in mice by activating farnesoid X receptor.
    Food & function, 2018, May-23, Volume: 9, Issue:5

    Topics: Animals; Bile Acids and Salts; Citrus; Coumarins; Humans; Liver; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Multidrug Resistance-Associated Proteins; Organic Anion Transporters, Sodium-Dependent; Protective Agents; Receptors, Cytoplasmic and Nuclear; Symporters; Thioacetamide; Transforming Growth Factor beta1

2018
Chemical Constituents of Thai Citrus hystrix and Their Antiausterity Activity against the PANC-1 Human Pancreatic Cancer Cell Line.
    Journal of natural products, 2018, 08-24, Volume: 81, Issue:8

    Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Size; Citrus; Coumarins; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Organelles; Pancreatic Neoplasms; Thailand; Tumor Microenvironment; Tumor Stem Cell Assay; Wound Healing

2018
Determination of citrus juice coumarins, furanocoumarins and methoxylated flavones using solid phase extraction and HPLC with photodiode array and fluorescence detection.
    Food chemistry, 2019, Jan-15, Volume: 271

    Topics: Beverages; Chromatography, High Pressure Liquid; Citrus; Coumarins; Flavones; Furocoumarins; Solid Phase Extraction

2019
Coumarin Analogues from the Citrus grandis (L.) Osbeck and Their Hepatoprotective Activity.
    Journal of agricultural and food chemistry, 2019, Feb-20, Volume: 67, Issue:7

    Topics: Alanine Transaminase; Aspartate Aminotransferases; Cell Line; Cell Survival; Citrus; Coumarins; Desiccation; Fruit; Galactosamine; Liver; Liver Diseases; Molecular Structure

2019
Auraptene/Naringin-Rich Fruit Juice of Citrus kawachiensis (Kawachi Bankan) Prevents Ischemia-Induced Neuronal Cell Death in Mouse Brain through Anti-Inflammatory Responses.
    Journal of nutritional science and vitaminology, 2019, Volume: 65, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Brain; Brain Ischemia; Cell Death; Citrus; Coumarins; Flavanones; Fruit and Vegetable Juices; Hippocampus; Mice; Neuroprotective Agents; Phytotherapy; Plant Preparations; Powders

2019
Influence of Pickling Process on
    Molecules (Basel, Switzerland), 2019, Mar-07, Volume: 24, Issue:5

    Topics: Citrus; Coumarins; Fixatives; Flavonoids; Gas Chromatography-Mass Spectrometry; Limonins; Metabolome; Metabolomics; Onions; Salts; Secondary Metabolism; Solid Phase Microextraction

2019
Hepatoprotection of auraptene from the peels of citrus fruits against 17α-ethinylestradiol-induced cholestasis in mice by activating farnesoid X receptor.
    Food & function, 2019, Jul-17, Volume: 10, Issue:7

    Topics: Animals; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Cholestasis; Cholesterol 7-alpha-Hydroxylase; Citrus; Coumarins; Liver; Male; Mice; Mice, Inbred C57BL; Organic Anion Transporters, Sodium-Dependent; Plant Extracts; Receptors, Cytoplasmic and Nuclear; Steroid 12-alpha-Hydroxylase; Sulfotransferases; Symporters

2019
Anti-inflammatory Effect of Pomelo Peel and Its Bioactive Coumarins.
    Journal of agricultural and food chemistry, 2019, Aug-14, Volume: 67, Issue:32

    Topics: Animals; Anti-Inflammatory Agents; Citrus; Coumarins; Dinoprostone; Edema; Fruit; Humans; Interleukin-1beta; Macrophages; Male; Mice; Mice, Inbred ICR; Plant Extracts; RAW 264.7 Cells; Tumor Necrosis Factor-alpha; Waste Products

2019
Volatile Compounds in Fruit Peels as Novel Biomarkers for the Identification of Four Citrus Species.
    Molecules (Basel, Switzerland), 2019, Dec-12, Volume: 24, Issue:24

    Topics: Citrus; Coumarins; Fruit; Polycyclic Sesquiterpenes; Sesquiterpenes; Volatile Organic Compounds

2019
Citrus Auraptene Induces Glial Cell Line-Derived Neurotrophic Factor in C6 Cells.
    International journal of molecular sciences, 2019, Dec-30, Volume: 21, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Brain; Cell Line, Tumor; Cell Survival; Citrus; Coumarins; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Neoplastic; Glial Cell Line-Derived Neurotrophic Factor; Glioma; Mice; Nerve Growth Factors; Neuroprotective Agents; Phosphorylation; Rats; RNA, Messenger; Signal Transduction

2019
Quantitative analysis of multicomponents by single marker combined with HPLC fingerprint qualitative analyses for comprehensive evaluation of Aurantii Fructus.
    Journal of separation science, 2020, Volume: 43, Issue:7

    Topics: Chromatography, High Pressure Liquid; Citrus; Coumarins; Disaccharides; Flavanones; Flavones; Flavonoids; Fruit; Hesperidin

2020
Citrus Auraptene Induces Expression of Brain-Derived Neurotrophic Factor in Neuro2a Cells.
    Molecules (Basel, Switzerland), 2020, Mar-03, Volume: 25, Issue:5

    Topics: Animals; Brain-Derived Neurotrophic Factor; Cell Line, Tumor; Cell Survival; Citrus; Coumarins; Enzyme-Linked Immunosorbent Assay; Glial Cell Line-Derived Neurotrophic Factor; Mice; RNA, Messenger

2020
Application of natural products as insecticide candidates: Semisynthesis and biological evaluation of some novel osthole-based esters.
    Bioorganic & medicinal chemistry letters, 2020, 08-01, Volume: 30, Issue:15

    Topics: Angelica; Animals; Biological Products; Cell Line; Cell Survival; Citrus; Cnidium; Coumarins; Dose-Response Relationship, Drug; Insecticides; Lepidoptera; Molecular Structure; Rats; Structure-Activity Relationship

2020
Citrus auraptene induces drug efflux transporter P-glycoprotein expression in human intestinal cells.
    Food & function, 2020, Jun-24, Volume: 11, Issue:6

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Line; Citrus; Coumarins; Food-Drug Interactions; Fruit; Humans; Intestines

2020
Identification of lipophilic components in Citri Reticulatae Pericarpium cultivars by supercritical CO
    Journal of separation science, 2020, Volume: 43, Issue:17

    Topics: Aldehydes; Carbon Dioxide; Chromatography, High Pressure Liquid; Chromatography, Supercritical Fluid; Citrus; Coumarins; Esters; Flavonoids; Hydrophobic and Hydrophilic Interactions; Limonins; Tandem Mass Spectrometry; Terpenes

2020
[Neuroprotective effects of the peel of Citrus kawachiensis (Kawachi Bankan) and auraptene in the hippocampus of hyperglycemia mice and global cerebral ischemia/reperfusion injury mice].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2020, Volume: 155, Issue:4

    Topics: Animals; Brain Ischemia; Citrus; Coumarins; Hippocampus; Hyperglycemia; Japan; Mice; Mice, Obese; Neuroprotective Agents; Reperfusion Injury

2020
Comparison of the chemical constituents of raw Fructus Aurantii and Fructus Aurantii stir-baked with bran, and the biological effects of auraptene.
    Journal of ethnopharmacology, 2021, Apr-06, Volume: 269

    Topics: Acetylcholinesterase; Animals; Chromatography, High Pressure Liquid; Citrus; Coumarins; Dietary Fiber; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Fruit; Hot Temperature; Intestine, Small; Mice; Muscle Contraction; Muscle, Smooth; Peristalsis; Rats, Sprague-Dawley

2021
Isolation and Characterization of Neuroprotective Components from Citrus Peel and Their Application as Functional Food.
    Chemical & pharmaceutical bulletin, 2021, Volume: 69, Issue:1

    Topics: Citrus; Coumarins; Flavonoids; Functional Food; Molecular Structure; Neuroprotective Agents; Plant Extracts

2021
Discovery and validation of quality markers of Fructus Aurantii against acetylcholinesterase using metabolomics and bioactivity assays.
    Journal of separation science, 2021, Volume: 44, Issue:11

    Topics: Acetylcholinesterase; Animals; Biomarkers; China; Cholinesterase Inhibitors; Citrus; Coumarins; Drug Discovery; Flavanones; Hesperidin; Male; Metabolomics; Rats; Rats, Sprague-Dawley

2021
Coumarins, psoralens, and quantitative
    Food chemistry, 2021, Oct-15, Volume: 359

    Topics: Citrus; Coumarins; Food Analysis; Fruit and Vegetable Juices; Furocoumarins; Magnetic Resonance Spectroscopy

2021
A Novel Auraptene-Enriched Citrus Peels-Based Blend with Enhanced Antioxidant Activity.
    Plant foods for human nutrition (Dordrecht, Netherlands), 2021, Volume: 76, Issue:3

    Topics: Antioxidants; Citrus; Coumarins; Fruit

2021
Characterization of two closely related citrus cultivars using UPLC-ESI-MS/MS-based widely targeted metabolomics.
    PloS one, 2021, Volume: 16, Issue:7

    Topics: Alkaloids; Chromatography, High Pressure Liquid; Citrus; Cluster Analysis; Coumarins; Flavonoids; Hydroxybenzoates; Metabolome; Metabolomics; Principal Component Analysis; Species Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2021
Retrieval of High Added Value Natural Bioactive Coumarins from Mandarin Juice-Making Industrial Byproduct.
    Molecules (Basel, Switzerland), 2021, Dec-12, Volume: 26, Issue:24

    Topics: Beverages; Biological Products; Chromatography, High Pressure Liquid; Citrus; Coumarins; Magnetic Resonance Spectroscopy; Molecular Structure; Oils, Volatile

2021
Supercritical fluid chromatography-tandem mass spectrometry of oxygen heterocyclic compounds in Citrus essential oils.
    Analytical and bioanalytical chemistry, 2022, Volume: 414, Issue:17

    Topics: Chromatography, High Pressure Liquid; Chromatography, Supercritical Fluid; Citrus; Coumarins; Furocoumarins; Oils, Volatile; Oxygen; Tandem Mass Spectrometry

2022
Auraptene, a citrus peel-derived natural product, prevents myocardial infarction-induced heart failure by activating PPARα in rats.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2022, Volume: 107

    Topics: Animals; Atrial Natriuretic Factor; Biological Products; Cardiomegaly; Citrus; Coumarins; Endothelin-1; Fibrosis; Heart Failure; Myocardial Infarction; Peroxisome Proliferators; Phenylephrine; PPAR alpha; Rats; Rats, Sprague-Dawley; RNA, Messenger

2022
[Three-dimensional multi-component analysis of Aurantii Fructus quality and research on influencing factors].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2023, Volume: 48, Issue:1

    Topics: Chromatography, High Pressure Liquid; Citrus; Coumarins; Drugs, Chinese Herbal; Flavonoids; Fruit

2023
Comparison of Chemical Compositions and Antioxidant Activities for the Immature Fruits of
    Molecules (Basel, Switzerland), 2023, Jun-28, Volume: 28, Issue:13

    Topics: Antioxidants; Chromatography, High Pressure Liquid; Citrus; Coumarins; Flavonoids; Fruit; Limonins

2023
Coumarins from Jinhua Finger Citron: Separation by Liquid-Liquid Chromatography and Potential Antitumor Activity.
    Molecules (Basel, Switzerland), 2023, Oct-03, Volume: 28, Issue:19

    Topics: Chromatography, Liquid; Citrus; Coumarins; HeLa Cells; Humans; Plant Extracts

2023
Integrated metabolomics and network pharmacology to reveal antioxidant mechanisms and potential pharmacological ingredients of citrus herbs.
    Food research international (Ottawa, Ont.), 2023, Volume: 174, Issue:Pt 1

    Topics: Antioxidants; Citrus; Coumarins; Flavonoids; Network Pharmacology

2023