Page last updated: 2024-09-03

ramatroban and mk-7246

ramatroban has been researched along with mk-7246 in 2 studies

Compound Research Comparison

Studies (ramatroban)	Trials (ramatroban)	Recent Studies (post-2010) (ramatroban)	Studies (mk-7246)	Trials (mk-7246)	Recent Studies (post-2010) (mk-7246)
142	10	28	6	0	5

Protein Interaction Comparison

Protein	Taxonomy	mk-7246 (IC50)
Cytochrome P450 3A4	Homo sapiens (human)	7
Cytochrome P450 2C9	Homo sapiens (human)	8.2
Prostaglandin D2 receptor	Homo sapiens (human)	1
Acyl-CoA:cholesterol acyltransferase	Oryctolagus cuniculus (rabbit)	2.503
Neuronal acetylcholine receptor subunit alpha-6	Mus musculus (house mouse)	0.006
Prostaglandin D2 receptor 2	Homo sapiens (human)	0.0047

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Baccei, C; Bain, G; Broadhead, A; Clark, RC; Coate, H; Evans, JF; Fagan, P; Hutchinson, JH; King, C; Lee, C; Lorrain, DS; Prasit, P; Prodanovich, P; Santini, A; Scott, JM; Stearns, BA; Stock, NS; Truong, YP	1
Beaulieu, C; Berthelette, C; Colucci, J; Crackower, MA; Dalton, C; Denis, D; Ducharme, Y; Friesen, RW; Gallant, M; Gervais, FG; Guay, D; Hamel, M; Houle, R; Kosjek, B; Krawczyk, CM; Lau, S; Leblanc, Y; Lee, EE; Levesque, JF; Mellon, C; Molinaro, C; Mullet, W; O'Neill, GP; O'Shea, P; Sawyer, N; Sillaots, S; Simard, D; Slipetz, D; Stocco, R; Sørensen, D; Truong, VL; Wang, Z; Wong, E; Wu, J; Zaghdane, H	1

Studies

Baccei, C; Bain, G; Broadhead, A; Clark, RC; Coate, H; Evans, JF; Fagan, P; Hutchinson, JH; King, C; Lee, C; Lorrain, DS; Prasit, P; Prodanovich, P; Santini, A; Scott, JM; Stearns, BA; Stock, NS; Truong, YP

Beaulieu, C; Berthelette, C; Colucci, J; Crackower, MA; Dalton, C; Denis, D; Ducharme, Y; Friesen, RW; Gallant, M; Gervais, FG; Guay, D; Hamel, M; Houle, R; Kosjek, B; Krawczyk, CM; Lau, S; Leblanc, Y; Lee, EE; Levesque, JF; Mellon, C; Molinaro, C; Mullet, W; O'Neill, GP; O'Shea, P; Sawyer, N; Sillaots, S; Simard, D; Slipetz, D; Stocco, R; Sørensen, D; Truong, VL; Wang, Z; Wong, E; Wu, J; Zaghdane, H

Other Studies

2 other study(ies) available for ramatroban and mk-7246

Article	Year
Novel tricyclic antagonists of the prostaglandin D2 receptor DP2 with efficacy in a murine model of allergic rhinitis. Bioorganic & medicinal chemistry letters, 2009, Aug-15, Volume: 19, Issue:16 Topics: Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Cytochrome P-450 Enzyme System; Disease Models, Animal; Female; Heterocyclic Compounds, 3-Ring; Humans; Mice; Receptors, Immunologic; Receptors, Prostaglandin; Rhinitis, Allergic, Perennial	2009
Discovery of MK-7246, a selective CRTH2 antagonist for the treatment of respiratory diseases. Bioorganic & medicinal chemistry letters, 2011, Jan-01, Volume: 21, Issue:1 Topics: Animals; Carbolines; Humans; Lung Diseases; Macaca mulatta; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Receptors, Immunologic; Receptors, Prostaglandin; Structure-Activity Relationship	2011

Article

Year

Novel tricyclic antagonists of the prostaglandin D2 receptor DP2 with efficacy in a murine model of allergic rhinitis.

Bioorganic & medicinal chemistry letters, 2009, Aug-15, Volume: 19, Issue:16

Topics: Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Cytochrome P-450 Enzyme System; Disease Models, Animal; Female; Heterocyclic Compounds, 3-Ring; Humans; Mice; Receptors, Immunologic; Receptors, Prostaglandin; Rhinitis, Allergic, Perennial

2009

Discovery of MK-7246, a selective CRTH2 antagonist for the treatment of respiratory diseases.

Bioorganic & medicinal chemistry letters, 2011, Jan-01, Volume: 21, Issue:1

Topics: Animals; Carbolines; Humans; Lung Diseases; Macaca mulatta; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Receptors, Immunologic; Receptors, Prostaglandin; Structure-Activity Relationship

2011