Page last updated: 2024-09-03
ramatroban and mk-7246
ramatroban has been researched along with mk-7246 in 2 studies
Compound Research Comparison
| Studies (ramatroban) | Trials (ramatroban) | Recent Studies (post-2010) (ramatroban) | Studies (mk-7246) | Trials (mk-7246) | Recent Studies (post-2010) (mk-7246) |
|---|---|---|---|---|---|
| 142 | 10 | 28 | 6 | 0 | 5 |
Protein Interaction Comparison
| Protein | Taxonomy | ramatroban (IC50) | mk-7246 (IC50) |
|---|---|---|---|
| Cytochrome P450 3A4 | Homo sapiens (human) | 7 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 8.2 | |
| Prostaglandin D2 receptor | Homo sapiens (human) | 1 | |
| Acyl-CoA:cholesterol acyltransferase | Oryctolagus cuniculus (rabbit) | 2.503 | |
| Neuronal acetylcholine receptor subunit alpha-6 | Mus musculus (house mouse) | 0.006 | |
| Prostaglandin D2 receptor 2 | Homo sapiens (human) | 0.0047 |
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Baccei, C; Bain, G; Broadhead, A; Clark, RC; Coate, H; Evans, JF; Fagan, P; Hutchinson, JH; King, C; Lee, C; Lorrain, DS; Prasit, P; Prodanovich, P; Santini, A; Scott, JM; Stearns, BA; Stock, NS; Truong, YP | 1 |
| Beaulieu, C; Berthelette, C; Colucci, J; Crackower, MA; Dalton, C; Denis, D; Ducharme, Y; Friesen, RW; Gallant, M; Gervais, FG; Guay, D; Hamel, M; Houle, R; Kosjek, B; Krawczyk, CM; Lau, S; Leblanc, Y; Lee, EE; Levesque, JF; Mellon, C; Molinaro, C; Mullet, W; O'Neill, GP; O'Shea, P; Sawyer, N; Sillaots, S; Simard, D; Slipetz, D; Stocco, R; Sørensen, D; Truong, VL; Wang, Z; Wong, E; Wu, J; Zaghdane, H | 1 |
Other Studies
2 other study(ies) available for ramatroban and mk-7246
| Article | Year |
|---|---|
Novel tricyclic antagonists of the prostaglandin D2 receptor DP2 with efficacy in a murine model of allergic rhinitis.
Topics: Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Cytochrome P-450 Enzyme System; Disease Models, Animal; Female; Heterocyclic Compounds, 3-Ring; Humans; Mice; Receptors, Immunologic; Receptors, Prostaglandin; Rhinitis, Allergic, Perennial | 2009 |
Discovery of MK-7246, a selective CRTH2 antagonist for the treatment of respiratory diseases.
Topics: Animals; Carbolines; Humans; Lung Diseases; Macaca mulatta; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Receptors, Immunologic; Receptors, Prostaglandin; Structure-Activity Relationship | 2011 |