pyrroles and rifampin
pyrroles has been researched along with rifampin in 35 studies
Research
Studies (35)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (28.57) | 18.7374 |
| 1990's | 1 (2.86) | 18.2507 |
| 2000's | 11 (31.43) | 29.6817 |
| 2010's | 7 (20.00) | 24.3611 |
| 2020's | 6 (17.14) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Friedman, PA; Goldberg, IH | 1 |
| Arcamone, F; Casazza, AM; Chandra, P; Di Marco, A; Gericke, D; Ghione, M; Giuliani, F; Götz, A; Soranzo, C; Thorbeck, R; Zunino, F | 1 |
| Brown, LR; Haworth, SR | 1 |
| Becker, Y; Kotler, M | 2 |
| Arioli, V; Maggi, N; Tamborini, G | 1 |
| Ishihama, A; Iwakura, Y; Yura, T | 1 |
| Khachatourians, GG; Tipper, DJ | 1 |
| Becher, H; Böhlandt, D; Grunicke, H; Puschendorf, B | 1 |
| Devine, LF; Hagerman, CR | 1 |
| Beale, SI; Rhie, G | 1 |
| Biava, M; Cesare Porretta, G; Deidda, D; Manetti, F; Pompei, R; Tafi, A | 1 |
| Alonso Lomillo, MA; Arcos Martinez, MJ; Kauffmann, JM | 1 |
| Backman, JT; Luurila, H; Neuvonen, M; Neuvonen, PJ | 1 |
| Benet, LZ; Huang, Y; Lau, YY; Okochi, H | 2 |
| Kivistö, KT | 1 |
| Benet, LZ; Frassetto, L; Huang, Y; Lau, YY | 1 |
| Cía, M; Martínez, M; Otermin, I; Pereda, A; Rivero, M | 1 |
| de Barros e Silva, MJ; de Paiva, TF; Fanelli, MF; Gimenes, DL; Rinck, JA | 1 |
| Chen, BL; Chen, Y; Guo, D; He, YJ; Kirchheiner, J; Li, Z; Tan, ZR; Tu, JH; Xu, LY; Yu, BN; Zhang, W; Zhou, G; Zhou, HH | 1 |
| Srinivas, NR | 1 |
| Rao, N | 1 |
| Alfonso, S; Battilocchio, C; Biava, M; Botta, M; De Logu, A; Manetti, F; Poce, G; Porretta, GC; Serra, N | 1 |
| Chang, JH; Cheong, J; Ly, J; Messick, K; Plise, E; Wright, M; Zhang, X | 1 |
| da Silva, MG; do Nascimento, DC; Duarte, RS; Ferreira, Jda S; Hacker, MA; Lara, FA; Lobato, LS; Monteiro, CP; Moraes, MO; Neumann, Ada S; Oliveira, DS; Pedrini, SC; Pereira, GM; Pessolani, MC; Ribeiro-Alves, M; Rosa, PS; Soares, CT | 1 |
| Bharate, JB; Bharate, SB; Joshi, P; Khan, IA; Kumar, A; Sharma, S; Singh, S; Vishwakarma, RA; Wani, A | 1 |
| Basher, MA; Bhakta, S; Brucoli, F; Evangelopoulos, D; Fox, KR; Guzman, JD; McHugh, TD; McMahon, E; Munshi, T | 1 |
| Brucoli, F; Fattorini, L; Giannoni, F; Iacobino, A | 1 |
| Irie, S; Ishizuka, H; Ishizuka, T; Kato, M; Kirigaya, Y; Nakatsu, T; Nishikawa, Y; Shimizu, T; Shiramoto, M; Uchimaru, H | 1 |
| Bruce, KD; Clifton, LA; Dreiss, CA; González-Gaitano, G; Harvey, RD; Picconi, P; Rahman, KM; Skoda, MWA; Valero, M; Vandera, KA; Woods, A; Zain, NMM | 1 |
| Igawa, Y; Ishizuka, H; Ishizuka, T; Shimizu, T; Watanabe, A; Yamada, M | 1 |
| Chen, X; Ji, T; Yeleswaram, S | 1 |
| Beelen, A; Curd, L; Goti, V; Horton, JK; Li, C; Sale, M; Tao, W | 1 |
| Cao, Y; Fu, Y; Gao, X; Jiang, X; Li, T; Li, X; Lin, P; Liu, Y; Shi, P; Sun, F; Wang, C; Zhang, Y | 1 |
Reviews
1 review(s) available for pyrroles and rifampin
| Article | Year |
|---|---|
Antibiotics and nucleic acids.
Topics: Anthracenes; Anthraquinones; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Benzazepines; Bleomycin; Chemical Phenomena; Chemistry; Dactinomycin; Daunorubicin; DNA; DNA Nucleotidyltransferases; Escherichia coli; Glycosides; Metabolism; Mitomycins; Models, Structural; Mycotoxins; Naphthacenes; Nucleic Acids; Olivomycins; Peptides; Plicamycin; Pyrroles; Rifampin; RNA; RNA Nucleotidyltransferases; Streptonigrin; Streptovaricin; Templates, Genetic | 1971 |
Trials
4 trial(s) available for pyrroles and rifampin
| Article | Year |
|---|---|
Rifampin markedly decreases and gemfibrozil increases the plasma concentrations of atorvastatin and its metabolites.
Topics: Adult; Area Under Curve; Atorvastatin; Cross-Over Studies; Drug Interactions; Female; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Male; Pyrroles; Rifampin | 2005 |
effect of OATP1B transporter inhibition on the pharmacokinetics of atorvastatin in healthy volunteers.
Topics: Administration, Oral; Adolescent; Adult; Area Under Curve; Atorvastatin; Bile; Binding, Competitive; Biological Transport; Cell Line; Cross-Over Studies; Enzyme Inhibitors; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infusions, Intravenous; Liver; Liver-Specific Organic Anion Transporter 1; Male; Middle Aged; Organic Anion Transporters; Pyrroles; Rifampin; Substrate Specificity; Tablets; Transfection | 2007 |
Physiologically based pharmacokinetic modelling to predict the clinical effect of CYP3A inhibitors/inducers on esaxerenone pharmacokinetics in healthy subjects and subjects with hepatic impairment.
Topics: Antihypertensive Agents; Area Under Curve; Computer Simulation; Cytochrome P-450 CYP3A Inducers; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Healthy Volunteers; Humans; Itraconazole; Japan; Liver Failure; Metabolic Clearance Rate; Models, Biological; Pyrroles; Rifampin; Sulfones | 2022 |
Pharmacokinetic Drug-Drug Interaction Studies Between Trilaciclib and Midazolam, Metformin, Rifampin, Itraconazole, and Topotecan in Healthy Volunteers and Patients with Extensive-Stage Small-Cell Lung Cancer.
Topics: Area Under Curve; Drug Interactions; Healthy Volunteers; Humans; Itraconazole; Lung Neoplasms; Metformin; Midazolam; Prospective Studies; Pyrimidines; Pyrroles; Rifampin; Topotecan | 2022 |
Other Studies
30 other study(ies) available for pyrroles and rifampin
| Article | Year |
|---|---|
Influence of some antitumor antibiotics on viral neoplasia. The role of molecular structure in the inhibition of DNA polymerases from RNA tumor viruses, viral multiplication and tumor growth by some antitumor antibiotics.
Topics: Amidines; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Antiviral Agents; Daunorubicin; DNA Nucleotidyltransferases; Female; Male; Mice; Oncogenic Viruses; Peptides; Piperazines; Pyrroles; Reverse Transcriptase Inhibitors; Rifampin; RNA Viruses; Structure-Activity Relationship; Virus Replication | 1972 |
Genetic analysis of ribonucleic acid polymerase mutants of Bacillus subtilis.
Topics: Alkanesulfonates; Anti-Bacterial Agents; Bacillus subtilis; Bacteriophage Typing; Chromosome Mapping; Crosses, Genetic; Culture Media; DNA-Directed RNA Polymerases; DNA, Bacterial; Drug Resistance, Microbial; Genetic Code; Mutation; Pyrans; Pyrroles; Rifampin; Spores, Bacterial; Streptovaricin; Temperature; Transduction, Genetic; Transformation, Genetic | 1973 |
Rifampicin and distamycin A as inhibitors of Rous sarcoma virus reverse transcriptase.
Topics: Anti-Bacterial Agents; Avian Sarcoma Viruses; Dactinomycin; DNA Nucleotidyltransferases; DNA, Viral; Hydrazones; Kinetics; Osmolar Concentration; Peptides; Pyrroles; Rifampin; Structure-Activity Relationship; Thymine Nucleotides; Tritium | 1971 |
[The effect of rifampicin and distamycin A on DNA synthesis by RNA-dependent DNA polymerases of Rous sarcoma virus].
Topics: Animals; Anti-Bacterial Agents; Avian Sarcoma Viruses; Chick Embryo; Dactinomycin; DNA Nucleotidyltransferases; DNA, Viral; Peptides; Pyrroles; Rifampin; RNA, Viral; Templates, Genetic | 1971 |
[Pyrrolo-rifamycin: synthesis and antibacterial properties].
Topics: Animals; Chromatography, Thin Layer; Enterococcus faecalis; Escherichia coli; Injections, Intradermal; Intestinal Absorption; Mice; Mycobacterium tuberculosis; Pseudomonas aeruginosa; Pyrroles; Rifampin; Staphylococcus; Streptococcus pneumoniae | 1969 |
RNA polymerase mutants of Escherichia coli. Streptolydigin resistance and its relation to rifampicin resistance.
Topics: Anti-Bacterial Agents; DNA-Directed RNA Polymerases; Drug Resistance, Microbial; Escherichia coli; Genetics, Microbial; Mutation; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; Pyrans; Pyrroles; Rifampin; RNA | 1973 |
Inhibition of messenger ribonucleic acid synthesis in Escherichia coli by thiolutin.
Topics: Acetamides; Anti-Bacterial Agents; Carbon Radioisotopes; Cell-Free System; Escherichia coli; Galactose; Galactosidases; Glycosides; Nitrobenzenes; Protein Biosynthesis; Pyrroles; Rifampin; RNA, Bacterial; RNA, Messenger; Transcription, Genetic; Tritium; Uridine | 1974 |
Effect of distamycin A on T4-DNA-directed RNA synthesis.
Topics: Amidines; Anti-Bacterial Agents; Coliphages; DNA Viruses; DNA-Directed RNA Polymerases; DNA, Viral; Escherichia coli; Kinetics; Oligopeptides; Protein Binding; Pyrroles; Ribonucleotides; Rifampin; Time Factors; Transcription, Genetic | 1974 |
Spectra of susceptibility of Neisseria meningitidis to antimicrobial agents in vitro.
Topics: Anti-Bacterial Agents; Anti-Infective Agents, Local; Carrier State; Disinfectants; Humans; Microbial Sensitivity Tests; Nasopharynx; Neisseria meningitidis; Pyrroles; Rifampin; Sulfonamides | 1970 |
Regulation of heme oxygenase activity in Cyanidium caldarium by light, glucose, and phycobilin precursors.
Topics: Aminolevulinic Acid; Bacterial Proteins; Chloramphenicol; Cyclohexanecarboxylic Acids; Cycloheximide; Darkness; Enzyme Induction; Gene Expression; Glucose; Heme Oxygenase (Decyclizing); Light; Light-Harvesting Protein Complexes; Phycobilins; Phycocyanin; Plant Proteins; Pyrroles; Rhodophyta; Rifampin; Tetrapyrroles | 1994 |
Importance of the thiomorpholine introduction in new pyrrole derivatives as antimycobacterial agents analogues of BM 212.
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Antifungal Agents; Antitubercular Agents; Antiviral Agents; Binding Sites; Chemical Phenomena; Chemistry, Physical; Indicators and Reagents; Isoniazid; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Morpholines; Mycobacterium; Piperazines; Pyrroles; Rifampin; Streptomycin; Structure-Activity Relationship | 2003 |
HRP-based biosensor for monitoring rifampicin.
Topics: Biosensing Techniques; Coated Materials, Biocompatible; Drug Contamination; Electrochemistry; Enzymes, Immobilized; Horseradish Peroxidase; Polymers; Pyrroles; Reproducibility of Results; Rifampin; Sensitivity and Specificity; Urinalysis | 2003 |
Multiple transporters affect the disposition of atorvastatin and its two active hydroxy metabolites: application of in vitro and ex situ systems.
Topics: Animals; Area Under Curve; Atorvastatin; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Cell Line; Dose-Response Relationship, Drug; Heptanoic Acids; Liver; Male; Microsomes, Liver; Organic Anion Transporters; Pyrroles; Rats; Rats, Sprague-Dawley; Rifampin; Tissue Distribution | 2006 |
Comments on "Multiple transporters affect the disposition of atorvastatin and its two active hydroxy metabolites: Application of in vitro and ex situ systems".
Topics: Animals; Atorvastatin; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Cytochrome P-450 CYP3A; Drug Interactions; Heptanoic Acids; Liver; Organic Anion Transporters; Pyrroles; Rats; Rifampin | 2006 |
Pharmacokinetics of atorvastatin and its hydroxy metabolites in rats and the effects of concomitant rifampicin single doses: relevance of first-pass effect from hepatic uptake transporters, and intestinal and hepatic metabolism.
Topics: Administration, Oral; Animals; Antibiotics, Antitubercular; Atorvastatin; Biological Availability; Drug Interactions; Heptanoic Acids; Hydroxylation; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Injections, Intravenous; Intestinal Mucosa; Intestines; Liver; Male; Microsomes; Organic Anion Transporters; Pyrroles; Rats; Rats, Sprague-Dawley; Rifampin | 2006 |
[Musculoskeletal adverse effects of levofloxacin].
Topics: Anti-Bacterial Agents; Arthralgia; Arthritis; Arthritis, Infectious; Arthroplasty, Replacement, Knee; Atorvastatin; Combined Modality Therapy; Debridement; Diagnosis, Differential; Doxycycline; Drug Interactions; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Levofloxacin; Middle Aged; Ofloxacin; Postoperative Complications; Prosthesis-Related Infections; Pyrroles; Recurrence; Reoperation; Rifampin; Thyroiditis, Autoimmune; Thyroxine; Trimethoprim, Sulfamethoxazole Drug Combination | 2006 |
Tuberculosis in a patient on temozolomide: a case report.
Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antibiotics, Antitubercular; Anticholesteremic Agents; Anticonvulsants; Antineoplastic Agents, Alkylating; Atorvastatin; Brain Neoplasms; Combined Modality Therapy; Cyclosporine; Dacarbazine; Dexamethasone; Female; Fluoxetine; Glioblastoma; Heptanoic Acids; Humans; Immunosuppressive Agents; Isoniazid; Middle Aged; Omeprazole; Phenobarbital; Prednisone; Pyrazinamide; Pyrroles; Radiotherapy; Red-Cell Aplasia, Pure; Rifampin; Temozolomide; Trimethoprim, Sulfamethoxazole Drug Combination; Tuberculosis, Pulmonary | 2009 |
Rifampicin alters atorvastatin plasma concentration on the basis of SLCO1B1 521T>C polymorphism.
Topics: Atorvastatin; Genotype; Heptanoic Acids; Humans; Kinetics; Liver-Specific Organic Anion Transporter 1; Male; Organic Anion Transporters; Polymorphism, Genetic; Pyrroles; Rifampin; Thymidine; Young Adult | 2009 |
Efflux transporter-mediated interactions with atorvastatin--interesting findings with multiple substrates: istradefylline, verapamil, and rifampicin.
Topics: Anticholesteremic Agents; Atorvastatin; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Heptanoic Acids; Humans; Liver-Specific Organic Anion Transporter 1; Organic Anion Transporters; Purines; Pyrroles; Rifampin; Verapamil | 2009 |
Re: Efflux transporter-mediated interactions with atorvastatin--interesting findings with multiple substrates: istradefylline, verapamil, and rifampicin.
Topics: Atorvastatin; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Organic Anion Transporters; Purines; Pyrroles; Research Design; Rifampin; Verapamil | 2011 |
Identification of a novel pyrrole derivative endowed with antimycobacterial activity and protection index comparable to that of the current antitubercular drugs streptomycin and rifampin.
Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Mycobacterium tuberculosis; Pyrroles; Rifampin; Streptomycin; Structure-Activity Relationship; Vero Cells | 2010 |
Differential effects of Rifampin and Ketoconazole on the blood and liver concentration of atorvastatin in wild-type and Cyp3a and Oatp1a/b knockout mice.
Topics: Animals; Atorvastatin; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Female; HEK293 Cells; Heptanoic Acids; Humans; Ketoconazole; Liver; Mice; Mice, Knockout; Organic Anion Transport Protein 1; Pyrroles; Rifampin | 2014 |
Statins increase rifampin mycobactericidal effect.
Topics: Animals; Antitubercular Agents; Atorvastatin; Cell Line; Drug Synergism; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leprosy; Macrophages; Mice; Mice, Inbred BALB C; Mycobacterium leprae; Mycobacterium tuberculosis; Pyrroles; Rifampin; Simvastatin | 2014 |
Discovery of 4-acetyl-3-(4-fluorophenyl)-1-(p-tolyl)-5-methylpyrrole as a dual inhibitor of human P-glycoprotein and Staphylococcus aureus Nor A efflux pump.
Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B; Bacterial Proteins; Binding Sites; Biological Transport; Caco-2 Cells; Ciprofloxacin; Coumarins; Dogs; Ethidium; Humans; Madin Darby Canine Kidney Cells; Mice, Inbred BALB C; Models, Molecular; Multidrug Resistance-Associated Proteins; Pyrroles; Rifampin; Staphylococcus aureus | 2015 |
DNA sequence-selective C8-linked pyrrolobenzodiazepine-heterocyclic polyamide conjugates show anti-tubercular-specific activities.
Topics: Animals; Antitubercular Agents; Base Sequence; Benzodiazepines; Deoxyribonuclease I; DNA Footprinting; DNA, Bacterial; Escherichia coli; Isoniazid; Mice; Microbial Sensitivity Tests; Mycobacterium bovis; Mycobacterium tuberculosis; Nylons; Pseudomonas putida; Pyrroles; RAW 264.7 Cells; Rhodococcus; Rifampin; Sequence Analysis, DNA | 2016 |
Activity of DNA-targeted C8-linked pyrrolobenzodiazepine-heterocyclic polyamide conjugates against aerobically and hypoxically grown Mycobacterium tuberculosis under acidic and neutral conditions.
Topics: Anaerobiosis; Antitubercular Agents; Benzodiazepines; Cell Line; Humans; Isoniazid; Mycobacterium tuberculosis; Nylons; Pyrroles; Rifampin; Tuberculosis, Pulmonary | 2018 |
Effects of itraconazole and rifampicin on the single-dose pharmacokinetics of the nonsteroidal mineralocorticoid receptor blocker esaxerenone in healthy Japanese subjects.
Topics: Area Under Curve; Cross-Over Studies; Cytochrome P-450 CYP3A; Drug Interactions; Healthy Volunteers; Humans; Itraconazole; Japan; Male; Pyrroles; Receptors, Mineralocorticoid; Rifampin; Sulfones | 2020 |
Antibiotic-in-Cyclodextrin-in-Liposomes: Formulation Development and Interactions with Model Bacterial Membranes.
Topics: Anti-Bacterial Agents; Bacterial Outer Membrane; Benzodiazepines; Cell Membrane Permeability; Cyclodextrins; Drug Compounding; Drug Delivery Systems; Drug Resistance, Bacterial; Escherichia coli; Lipid Bilayers; Liposomes; Membrane Fusion; Models, Biological; Pyrroles; Rifampin; Solubility | 2020 |
Evaluation of drug-drug interaction potential for pemigatinib using physiologically based pharmacokinetic modeling.
Topics: Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Humans; Itraconazole; Models, Biological; Morpholines; Pyrimidines; Pyrroles; Rifampin | 2022 |
The effect of rifampin on the pharmacokinetics of famitinib in healthy subjects.
Topics: Chromatography, Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Drug Interactions; Healthy Volunteers; Humans; Indoles; Male; Pyrroles; Rifampin; Tandem Mass Spectrometry | 2022 |