pyrroles and pd 98059

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Aminoquinolines; Animals; Avoidance Learning; Carbazoles; Entorhinal Cortex; Enzyme Inhibitors; Flavonoids; Guanylate Cyclase; Hippocampus; Indoles; Inhibition, Psychological; Male; Memory; Memory, Short-Term; Phenols; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Wistar; Sodium Chloride; Staurosporine

Topics: Animals; Cadherins; Carbazoles; Cartilage; Cell Differentiation; Chick Embryo; Chondrogenesis; Cyclic AMP-Dependent Protein Kinases; Embryonic Induction; Enzyme Inhibitors; Fibronectins; Flavonoids; Indoles; Isoenzymes; Isoquinolines; Mesoderm; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Protein Kinase C; Protein Kinase C-alpha; Pyrroles; Receptors, Fibronectin; Signal Transduction; Sulfonamides

Topics: Androstadienes; Angiogenesis Inhibitors; Biomarkers, Tumor; Blotting, Western; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Fluorescent Antibody Technique; Humans; Indoles; Liver Neoplasms; Lymphokines; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Neovascularization, Pathologic; Oxindoles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Propionates; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Wortmannin

Topics: Cell Differentiation; Culture Media, Serum-Free; Enzyme Inhibitors; Flavonoids; GAP-43 Protein; Gene Expression Regulation; Genes, Reporter; Isoenzymes; Mesylates; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neurites; Neuroblastoma; Neurons; Neuropeptide Y; Phosphorylation; Promoter Regions, Genetic; Protein Kinase C; Protein Kinase C beta; Pyrroles; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Carbazoles; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Flavonoids; Genistein; Indoles; Isoquinolines; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Phosphorylation; Plasminogen Activator Inhibitor 1; Protein Kinase C; Protein-Tyrosine Kinases; Pyrroles; Rats; Signal Transduction; src-Family Kinases; Stilbenes; Sulfonamides; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetophenones; Alkaloids; Androstadienes; Animals; Antibodies; Benzophenanthridines; Benzopyrans; Blotting, Western; Brain-Derived Neurotrophic Factor; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Carbazoles; Cell Nucleus; Chromones; Cyclic AMP Response Element-Binding Protein; Cytosol; Enzyme Inhibitors; Flavonoids; Hippocampus; Imidazoles; Immunohistochemistry; In Vitro Techniques; Indoles; Intracellular Signaling Peptides and Proteins; Male; Morpholines; Naphthalenes; Phenanthridines; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Pyridines; Pyrroles; Rats; Signal Transduction; Time Factors; Tyrphostins; Wortmannin

Topics: Animals; Cell Survival; Cells, Cultured; Dopamine; Enzyme Inhibitors; Fibroblast Growth Factors; Flavonoids; In Situ Hybridization; Mesencephalon; Mitogen-Activated Protein Kinases; Neurons; Phosphorylation; Pyrroles; Rats; Rats, Wistar; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; RNA, Messenger; Signal Transduction

Topics: Animals; Cattle; Cell Division; Cells, Cultured; Choroidal Neovascularization; Endothelium, Corneal; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Indoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neovascularization, Physiologic; Phosphorylation; Protein-Tyrosine Kinases; Pyrroles; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2

Topics: Acetylcysteine; Adult; Aged; Anti-Infective Agents; Antioxidants; Arteriosclerosis; Cells, Cultured; Curcumin; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Female; Flavonoids; Foam Cells; Gene Expression Regulation; Glucose; Glycation End Products, Advanced; Humans; Hyperglycemia; Macrophages; Male; MAP Kinase Signaling System; Mesylates; Middle Aged; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NF-kappa B; Nitriles; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Protein Processing, Post-Translational; Pyrroles; Receptors, LDL; RNA, Messenger; Signal Transduction; Sulfones; Transcription Factor AP-1; Tumor Necrosis Factor-alpha

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3-L1 Cells; Adipocytes; Animals; Benzylamines; Biphenyl Compounds; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cell Survival; Cyclic AMP-Dependent Protein Kinases; Flavonoids; Glycerol; Hydroxycholesterols; Indoles; Lignans; Lipolysis; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Naphthalenes; Oleic Acid; Phosphorylation; Protein Kinase C; Pyrroles; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Vacuoles

Topics: Analysis of Variance; Animals; Animals, Newborn; Calbindins; Carbazoles; Cell Count; Cell Differentiation; Corticotropin-Releasing Hormone; Dendrites; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Flavonoids; Hippocampus; Humans; Immunohistochemistry; In Vitro Techniques; Indoles; Linear Models; Neuroprotective Agents; Purkinje Cells; Pyrimidines; Pyrroles; Rats; S100 Calcium Binding Protein G; Time Factors; Urocortins

Topics: Adenosine Triphosphate; Alkaloids; Aminoimidazole Carboxamide; Animals; Antimycin A; Benzophenanthridines; Brefeldin A; Carbazoles; Cell Hypoxia; Cells, Cultured; Connexin 43; Cycloheximide; Deoxyglucose; Flavonoids; Imidazoles; Indoles; JNK Mitogen-Activated Protein Kinases; Maleimides; Myocardial Contraction; Myocytes, Cardiac; Okadaic Acid; Ouabain; Phenanthridines; Phosphorylation; Potassium Cyanide; Protein Processing, Post-Translational; Pyridines; Pyrroles; Rats; Recombinant Fusion Proteins; Ribonucleotides; Staurosporine; Tacrolimus; Tetradecanoylphorbol Acetate

Topics: Animals; Axons; Carbazoles; Cell Survival; Chromones; Ciliary Neurotrophic Factor; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Flavonoids; Indoles; MAP Kinase Signaling System; Morpholines; Nerve Regeneration; Optic Nerve Injuries; Peroneal Nerve; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrroles; Rats; Rats, Inbred F344; Receptor, Ciliary Neurotrophic Factor; Retinal Ganglion Cells; Signal Transduction; STAT3 Transcription Factor; Thionucleotides; Trans-Activators; Tyrphostins; Up-Regulation

Topics: Animals; Aorta; Blood Glucose; Cell Division; Cell Movement; Cells, Cultured; Constriction, Pathologic; DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Activation; Femoral Artery; Flavonoids; Humans; Immediate-Early Proteins; Indoles; Janus Kinase 2; JNK Mitogen-Activated Protein Kinases; Maleimides; Mesylates; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; Peroxidase; Protein Kinase C; Protein Kinase C beta; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Pyrroles; Signal Transduction; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription Factors; Tunica Intima

Topics: Amides; Aorta; Atorvastatin; Bacterial Proteins; Bacterial Toxins; Butadienes; Carcinoma, Hepatocellular; CCAAT-Enhancer-Binding Proteins; Cell Line, Tumor; Drug Synergism; Flavonoids; Group II Phospholipases A2; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interferon-gamma; Janus Kinase 2; Lovastatin; Myocytes, Smooth Muscle; NF-kappa B; Nitriles; Phospholipases A; Phospholipases A2; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Pyridines; Pyrroles; RNA Stability; Up-Regulation

Topics: Animals; Catecholamines; Cell Line, Tumor; Cyclic AMP-Dependent Protein Kinases; Flavonoids; Hypothalamic Hormones; Indoles; Isoquinolines; MAP Kinase Signaling System; Neuropeptides; Pheochromocytoma; Prolactin-Releasing Hormone; Protein Kinase C; Pyrroles; Rats; RNA, Messenger; Signal Transduction; Stimulation, Chemical; Sulfonamides; Tyrosine 3-Monooxygenase

Topics: Adaptation, Physiological; alpha 1-Antitrypsin; Apoptosis; bcl-2-Associated X Protein; Benzoflavones; Butadienes; Cell Line; DNA Fragmentation; Epidermal Growth Factor; Epithelial Cells; Female; Ferric Compounds; Flavonoids; Glutathione; Humans; Hydrogen Peroxide; Lipopolysaccharides; Mitogen-Activated Protein Kinases; Nitriles; Nitro Compounds; Phenanthrolines; Polychlorinated Dibenzodioxins; Pyrimidines; Pyrroles; Quaternary Ammonium Compounds; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Transforming Growth Factor alpha; Ultraviolet Rays

Topics: Animals; Anticholesteremic Agents; Atorvastatin; Blotting, Western; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Heptanoic Acids; Imidazoles; Mice; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Pyrroles; Vascular Endothelial Growth Factor A

Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Atorvastatin; Benzimidazoles; Biphenyl Compounds; Calcium Channels, T-Type; Cells, Cultured; Endothelial Cells; Flavonoids; Gene Expression; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Microscopy, Fluorescence; Pyrroles; ras Proteins; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tetrazoles; Vasoconstrictor Agents

Topics: Adenylyl Cyclases; Aprotinin; Cell Differentiation; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activators; Epidermal Growth Factor; Fibroblast Growth Factors; Flavonoids; Humans; Indoles; Insulin; Iodine; Iodine Radioisotopes; Maleimides; Mesylates; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Plasminogen Inactivators; Protein Kinase C; Protein Kinase C beta; Protein Kinase Inhibitors; Pyrroles; RNA, Messenger; Serine Proteinase Inhibitors; Signal Transduction; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Time Factors; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator

Topics: Androstadienes; Animals; Bicarbonates; Calcium Signaling; Carbazoles; Chromones; Cyclic AMP; Dinoprostone; Duodenum; Flavonoids; Genistein; Imines; Indoles; Intestinal Mucosa; Mice; Mitogen-Activated Protein Kinase Kinases; Morpholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; Pyrroles; Signal Transduction; Sulfonamides; Verapamil; Wortmannin

Topics: Animals; Astrocytes; Cells, Cultured; Encephalitis; Enzyme Activation; Enzyme Inhibitors; Extracellular Matrix; Flavonoids; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinase 3; Pyrroles; Quinazolines; Rats; Receptor, PAR-1; Thrombin

Topics: Adenine; Androstadienes; Aorta; Carbazoles; Cell Proliferation; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Flavonoids; Ghrelin; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrroles; Wortmannin

Topics: Animals; Butadienes; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dendrites; Electric Stimulation; Excitatory Postsynaptic Potentials; Extracellular Signal-Regulated MAP Kinases; Flavonoids; In Vitro Techniques; Learning; Long-Term Potentiation; Male; Nitriles; Protein Kinase Inhibitors; Pyramidal Cells; Pyrroles; Rats; Rats, Sprague-Dawley; Signal Transduction

Topics: Adaptor Proteins, Signal Transducing; Cell Line; Cell Movement; Cells, Cultured; CSK Tyrosine-Protein Kinase; Enzyme Inhibitors; Flavonoids; Humans; Hydrogen Peroxide; Keratinocytes; Ligands; Membrane Proteins; Mitogen-Activated Protein Kinase 3; Phosphorylation; Protein-Tyrosine Kinases; Pyrroles; Reactive Oxygen Species; Receptor, Fibroblast Growth Factor, Type 2; Signal Transduction; src-Family Kinases; Wound Healing

Topics: Animals; Cell Line; Cyclooxygenase 2; Dinoprostone; Enzyme Induction; Enzyme Inhibitors; Epoprostenol; Flavonoids; Imidazoles; Macrophages, Peritoneal; Mice; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Pyridines; Pyrroles; Quinazolines; Receptor, PAR-1; Signal Transduction; Thrombin; Thromboxane A2

Topics: Analysis of Variance; Animals; Astrocytes; Blotting, Western; Cells, Cultured; Chromones; Culture Media, Conditioned; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibrinolysin; Fibrinolytic Agents; Fibroblast Growth Factors; Flavonoids; Immunohistochemistry; Microglia; Morpholines; Nerve Growth Factors; Neurons; Phosphatidylinositol 3-Kinases; Phosphorylation; Plasminogen; Proto-Oncogene Proteins c-akt; Pyrroles; Quinazolines; Rats; Receptor, PAR-1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Transforming Growth Factor beta3

Topics: Apoptosis; bcl-X Protein; Bone Marrow Cells; Calcium-Calmodulin-Dependent Protein Kinases; Cytochromes c; Drug Resistance, Neoplasm; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression Regulation, Leukemic; Humans; Interleukin-4; Janus Kinase 3; Leukemia, Lymphocytic, Chronic, B-Cell; Myeloid Cell Leukemia Sequence 1 Protein; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; Pyrroles; STAT6 Transcription Factor; Stromal Cells; T-Lymphocytes; Tumor Cells, Cultured; Tumor Suppressor Protein p53

Topics: Animals; Carbazoles; Cell Extracts; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cyclin-Dependent Kinases; Female; Flavonoids; Granulosa Cells; Insulin-Like Growth Factor I; Kinetin; Mitogen-Activated Protein Kinases; Proliferating Cell Nuclear Antigen; Protein Kinase Inhibitors; Pyrroles; Rabbits

Topics: Alkaloids; Animals; Atorvastatin; Cardiovascular Agents; Cell Cycle; Cell Proliferation; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Drugs, Chinese Herbal; Dual Specificity Phosphatase 1; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Glycosides; Heptanoic Acids; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Platelet-Derived Growth Factor; Pyrroles; Rats; Rats, Sprague-Dawley; Signal Transduction

Topics: Animals; Carbazoles; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Flavonoids; Gastrointestinal Motility; Ileum; Isoxazoles; Lipopolysaccharides; Macrophages; Male; Mice; Nitric Oxide Synthase Type II; Pyrroles; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Sulfones; Up-Regulation

Topics: Animals; Calcification, Physiologic; Cell Nucleus; Culture Media, Conditioned; Fibroblast Growth Factor 2; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Flavonoids; Gene Expression Regulation; Genetic Vectors; Humans; Male; Mesenchymal Stem Cells; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinases; Models, Biological; Molecular Weight; Neutralization Tests; Osteocalcin; Osteogenesis; Phosphorylation; Protein Isoforms; Pyrroles; Receptors, Fibroblast Growth Factor; RNA, Messenger; Time Factors

Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Antineoplastic Combined Chemotherapy Protocols; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Activation; Flavonoids; Humans; Indoles; Phosphorylation; Protein-Tyrosine Kinases; Pyrroles; Receptor Protein-Tyrosine Kinases; Sunitinib

Topics: Angiogenesis Inhibitors; Cell Culture Techniques; Cell Differentiation; Cell Hypoxia; Coculture Techniques; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Endothelial Cells; Flavonoids; Human Umbilical Vein Endothelial Cells; Humans; Indoles; Nitrobenzenes; Osteogenesis; Periodontal Ligament; Prostaglandin Antagonists; Protein Kinase Inhibitors; Pyrroles; Signal Transduction; Stem Cells; Sulfonamides; Thiophenes; Triazoles; Vascular Endothelial Growth Factor A; Xanthones

Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Indoles; Kidney Neoplasms; Phosphotransferases (Alcohol Group Acceptor); Pyrroles; Receptor, Platelet-Derived Growth Factor beta; Sunitinib

Topics: AIDS Dementia Complex; Animals; Antineoplastic Agents; Cyclin-Dependent Kinase 5; Dasatinib; Erlotinib Hydrochloride; Flavonoids; HIV Envelope Protein gp120; In Vitro Techniques; Indoles; Lapatinib; Mice; Mice, Transgenic; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Protein Kinase Inhibitors; Purines; Pyrimidines; Pyrroles; Quinazolines; Rats; Roscovitine; Sunitinib; Thiazoles

Topics: Animals; Cells, Cultured; Chondrocytes; Enzyme Activation; Flavonoids; Imidazoles; Isoquinolines; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Pyrroles; Quinoxalines; Rats; Smad2 Protein; Smad3 Protein; Tissue Inhibitor of Metalloproteinase-3; Transforming Growth Factor beta1; Up-Regulation

Topics: Animals; Apoptosis; Cell Fusion; Cell Proliferation; Cells, Cultured; Down-Regulation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression; Gene Silencing; Indoles; MAP Kinase Signaling System; Membrane Proteins; Mice, Inbred C57BL; Nerve Tissue Proteins; Osteoclasts; Pyrroles; RANK Ligand; Vacuolar Proton-Translocating ATPases

Topics: Actins; Cell Line; Cell Proliferation; Collagen Type I; Fetus; Fibroblasts; Fibrosis; Flavonoids; Gene Expression Regulation; Humans; Isoquinolines; Lung; Mitogen-Activated Protein Kinase 1; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Pyridines; Pyrroles; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta1

Topics: Aggrecans; Animals; Cartilage, Articular; Chondrocytes; Collagen Type II; Enzyme Activation; Female; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Isoquinolines; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Primary Cell Culture; Protein Serine-Threonine Kinases; Pyridines; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Recombinant Proteins; Signal Transduction; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta1

Topics: Antineoplastic Agents; Apoptosis; Cadherins; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Flavonoids; Humans; Integrin beta1; Isoflavones; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phorbol Esters; Protein Kinase C-alpha; Pyrroles; Quinazolines; Signal Transduction

Topics: Adenylyl Cyclases; Animals; Carbazoles; Clathrin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endosomes; Flavonoids; Guinea Pigs; Heart; Humans; MAP Kinase Signaling System; Myocardium; Neurons; Pituitary Adenylate Cyclase-Activating Polypeptide; Pyrroles; Receptors, G-Protein-Coupled; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I

Topics: Adult; Aged; Antineoplastic Agents; Apoptosis; Case-Control Studies; Cell Line, Tumor; Chromones; Disease Progression; Dose-Response Relationship, Drug; Female; Flavonoids; Fusion Proteins, bcr-abl; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Morpholines; Myeloid Cells; Philadelphia Chromosome; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Quinazolines; Receptor, PAR-1; Signal Transduction; Treatment Outcome; Vascular Endothelial Growth Factor A