Page last updated: 2024-08-18

pyrroles and oroidin

pyrroles has been researched along with oroidin in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (2.50)18.2507
2000's16 (40.00)29.6817
2010's20 (50.00)24.3611
2020's3 (7.50)2.80

Authors

AuthorsStudies
Escalona de Motta, G; Morales, JJ; Ortiz, M; Rodríguez, AD; Rosa, R; Silva, W1
Assmann, M; Köck, M; Zea, S1
Assmann, M; Bickmeyer, U; Drechsler, C; Köck, M1
Crews, P; Gautschi, JT; Holman, TR; Whitman, S1
Dilley, A; Dransfield, PJ; Romo, D; Wang, S1
Breckle, G; Lindel, T; Pöverlein, C1
Chen, C; Tan, X1
Al-Mourabit, A; Schroif-Gregoire, C; Travert, N; Zaparucha, A1
Grube, A; Köck, M1
Ballard, TE; Melander, C; Richards, JJ1
Ballard, TE; Huigens, RW; Melander, C; Richards, JJ1
Arndt, HD; Riedrich, M1
Melander, C; Reed, CS; Richards, JJ1
Ballard, TE; Melander, C; Richards, JJ; Wolfe, AL1
Aquino, A; Ballard, TE; Melander, C; Reed, CS; Richards, JJ1
Dias, HV; Lovely, CJ; Mukherjee, S; Sivappa, R1
Ballard, TE; Cavanagh, J; Mathies, LD; Melander, C; Reyes, S; Richards, JJ; Stowe, SD; Tucker, AT1
Horne, DA; Jove, R; Ma, Y; Nam, S; Yakushijin, K1
Molinski, TF; Morinaka, BI; Reyes, JC; Romo, D; Wang, YG; Wolff, JJ1
Lovely, CJ; Mukherjee, S; Sivappa, R; Yousufuddin, M1
Berlinck, RG; da Silva, FR; Ferreira, PF; Ferreira-Pereira, A; Garcia-Gomes, AS; Muricy, G; Pereira, FR; Rangel, LP; Tessis, AC1
Bhandari, MR; Lovely, CJ; Yousufuddin, M1
Al Mourabit, A; Cachet, N; Genta-Jouve, G; Holderith, S; Jeffree, R; Oberhänsli, F; Teyssié, JL; Thomas, OP1
Molinski, TF; Morinaka, BI; Romo, D; Stout, EP; Wang, YG1
Baran, PS; Feldman, KS; Fodor, MD; Hewlett, NM; Lansdell, TA; Seiple, IB; Skoumbourdis, AP; Su, S; Tepe, JJ1
Al-Mourabit, A; Appenzeller, J; Ermolenko, L; Lejeune, C; Martin, MT; Tian, H1
Dhawane, AN; Golen, JA; Kumbam, V; Lovely, CJ; Rasapalli, S; Rheingold, AL1
Karpoormath, R; Rane, R; Sahu, N; Shah, C1
Dyson, L; McCluskey, A; Sakoff, JA; Wright, AD; Young, KA1
Hodnik, Ž; Ilaš, J; Kikelj, D; Mašič, LP; Montalvão, S; Nawrot, DA; Tammela, P; Zidar, N; Žula, A1
Molinski, TF; Morinaka, BI; Wang, X1
Hodnik, Ž; Ilaš, J; Jakopin, Ž; Kikelj, D; Peterlin Mašič, L; Sollner Dolenc, M; Węgrzyn, G; Zidar, N; Žula, A; Łoś, JM; Łoś, M1
Lamont, RJ; Melander, C; Melander, RJ; Wright, CJ; Wu, H1
Fromont, J; Gonoi, T; Kashiwada, Y; Kobayashi, J; Kusama, T; Sakai, K; Tanaka, N1
Al Mourabit, A; Moriou, C; Sauleau, P1
Kikelj, D; Lillsunde, KE; Tammela, P; Tomašič, T1
Ilaš, J; Kikelj, D; Kirby, RW; Mašič, LP; Peigneur, S; Rogers, M; Tomašič, T; Tytgat, J; Zidar, N; Žula, A1
Carmeli, S; Fridman, M; Ilan, M; Kovalerchik, D; Mahajni, A; Schlesinger, P; Shefer, S; Singh, RP1
Bhandari, MR; Doundoulakis, T; Gout, D; Lovely, CJ; Singh, RP; Torres, FM1
Boyko, M; Frank, D; Grinshpun, J; Gruenbaum, BF; Knyazer, B; Kuts, R; Melamed, I; Savir, S; Vinokur, M; Zlotnik, A1

Reviews

1 review(s) available for pyrroles and oroidin

ArticleYear
Marine bromopyrrole alkaloids: synthesis and diverse medicinal applications.
    Current topics in medicinal chemistry, 2014, Volume: 14, Issue:2

    Topics: Alkaloids; Angiogenesis Inhibitors; Animals; Anti-Infective Agents; Antineoplastic Agents; Aquatic Organisms; Biofilms; Chemistry Techniques, Synthetic; Humans; Porifera; Pyrroles; Serotonin Antagonists

2014

Other Studies

39 other study(ies) available for pyrroles and oroidin

ArticleYear
Anti-muscarinic activity of a family of C11N5 compounds isolated from Agelas sponges.
    Experientia, 1992, Sep-15, Volume: 48, Issue:9

    Topics: Alkaloids; Animals; Binding, Competitive; Brain; Cell Membrane; In Vitro Techniques; Parasympatholytics; Porifera; Pyrroles; Radioligand Assay; Rats; Receptors, Muscarinic

1992
Sventrin, a new bromopyrrole alkaloid from the Caribbean sponge Agelas sventres.
    Journal of natural products, 2001, Volume: 64, Issue:12

    Topics: Alkaloids; Animals; Bahamas; Carboxylic Acids; Chromatography, High Pressure Liquid; Feeding Behavior; Fishes; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Porifera; Pyrroles; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared

2001
Brominated pyrrole alkaloids from marine Agelas sponges reduce depolarization-induced cellular calcium elevation.
    Toxicon : official journal of the International Society on Toxinology, 2004, Volume: 44, Issue:1

    Topics: Animals; Aplysia; Biological Transport, Active; Calcium; Calcium Channels; Carboxylic Acids; Fluorescence; Germany; Hydrocarbons, Brominated; Neurons, Afferent; PC12 Cells; Porifera; Pyrroles; Rats

2004
An analysis of phakellin and oroidin structures stimulated by further study of an Agelas sponge.
    Journal of natural products, 2004, Volume: 67, Issue:8

    Topics: Alkaloids; Animals; Enzyme Inhibitors; Guanidines; Inhibitory Concentration 50; Lipoxygenase Inhibitors; Molecular Structure; Papua New Guinea; Piperazines; Porifera; Pyrroles; Spiro Compounds

2004
Highly regioselective Diels-Alder reactions toward oroidin alkaloids: use of a tosylvinyl moiety as a nitrogen masking group with adjustable electronics.
    Organic letters, 2005, Apr-28, Volume: 7, Issue:9

    Topics: Alkaloids; Amines; Molecular Structure; Pyrroles; Spiro Compounds; Stereoisomerism; Tosyl Compounds; Vinyl Compounds

2005
Diels-Alder reactions of oroidin and model compounds.
    Organic letters, 2006, Mar-02, Volume: 8, Issue:5

    Topics: Alkaloids; Animals; Cyclization; Models, Molecular; Molecular Structure; Porifera; Pyrroles; Temperature

2006
Regiocontrol in Mn(III)-mediated oxidative heterobicyclizations: access to the core skeletons of oroidin dimers.
    Angewandte Chemie (International ed. in English), 2006, Jun-26, Volume: 45, Issue:26

    Topics: Cyclization; Dimerization; Free Radicals; Manganese; Molecular Structure; Oxidation-Reduction; Pyrroles

2006
Direct access to marine pyrrole-2-aminoimidazoles, oroidin, and derivatives, via new acyl-1,2-dihydropyridin intermediates.
    Organic letters, 2006, Jul-06, Volume: 8, Issue:14

    Topics: Catalysis; Imidazoles; Indicators and Reagents; Marine Biology; Molecular Structure; Oxidation-Reduction; Pyridines; Pyrroles

2006
Oxocyclostylidol, an intramolecular cyclized oroidin derivative from the marine sponge Stylissa caribica.
    Journal of natural products, 2006, Volume: 69, Issue:8

    Topics: Alkaloids; Animals; Caribbean Region; Cyclization; Marine Biology; Molecular Structure; Porifera; Pyrroles

2006
Inhibition and dispersion of Pseudomonas aeruginosa biofilms with reverse amide 2-aminoimidazole oroidin analogues.
    Organic & biomolecular chemistry, 2008, Apr-21, Volume: 6, Issue:8

    Topics: Anti-Bacterial Agents; Biofilms; Humans; Imidazoles; Microbial Sensitivity Tests; Molecular Structure; Pseudomonas aeruginosa; Pyrroles; Small Molecule Libraries; Stereoisomerism; Structure-Activity Relationship

2008
Synthesis and screening of an oroidin library against Pseudomonas aeruginosa biofilms.
    Chembiochem : a European journal of chemical biology, 2008, May-23, Volume: 9, Issue:8

    Topics: Biofilms; Cross-Linking Reagents; Databases, Factual; Drug Design; Drug Evaluation, Preclinical; Molecular Structure; Pseudomonas aeruginosa; Pyrroles; Structure-Activity Relationship

2008
Synthesis of marine alkaloids from the oroidin family.
    Angewandte Chemie (International ed. in English), 2008, Volume: 47, Issue:26

    Topics: Alkaloids; Biological Factors; Imidazoles; Molecular Structure; Oxidation-Reduction; Pyrroles

2008
Effects of N-pyrrole substitution on the anti-biofilm activities of oroidin derivatives against Acinetobacter baumannii.
    Bioorganic & medicinal chemistry letters, 2008, Aug-01, Volume: 18, Issue:15

    Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Biofilms; Humans; Imidazoles; Microbial Sensitivity Tests; Molecular Structure; Pyrroles; Small Molecule Libraries; Stereoisomerism; Structure-Activity Relationship

2008
Synthesis and antibiofilm activity of a second-generation reverse-amide oroidin library: a structure-activity relationship study.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2008, Volume: 14, Issue:34

    Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Biofilms; Drug Design; Imidazoles; Microbial Sensitivity Tests; Molecular Structure; Pseudomonas aeruginosa; Pyrroles; Small Molecule Libraries; Stereoisomerism; Structure-Activity Relationship

2008
Antibiofilm activity of a diverse oroidin library generated through reductive acylation.
    The Journal of organic chemistry, 2009, Feb-20, Volume: 74, Issue:4

    Topics: Acylation; Biofilms; Oxidation-Reduction; Proteobacteria; Pyrroles; Small Molecule Libraries

2009
Studies toward the total synthesis of the oroidin dimers.
    Organic & biomolecular chemistry, 2009, Aug-21, Volume: 7, Issue:16

    Topics: Alkaloids; Dimerization; Guanidines; Imidazoles; Marine Biology; Polymers; Pyrroles; Spiro Compounds

2009
Amide isosteres of oroidin: assessment of antibiofilm activity and C. elegans toxicity.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Amides; Animals; Anti-Bacterial Agents; Biofilms; Caenorhabditis elegans; Pseudomonas aeruginosa; Pyrroles; Structure-Activity Relationship; Sulfonamides; Thiourea; Urea

2009
Synthesis and anticancer activities of ageladine A and structural analogs.
    Bioorganic & medicinal chemistry letters, 2010, Jan-01, Volume: 20, Issue:1

    Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Imidazoles; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Oxidation-Reduction; Pyrroles; Structure-Activity Relationship

2010
Synthesis of 7-(15)N-Oroidin and evaluation of utility for biosynthetic studies of pyrrole-imidazole alkaloids by microscale (1)H-(15)N HSQC and FTMS.
    Journal of natural products, 2010, Mar-26, Volume: 73, Issue:3

    Topics: Alkaloids; Animals; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Porifera; Pyrroles

2010
Asymmetric total synthesis of ent-cyclooroidin.
    Organic letters, 2010, Nov-05, Volume: 12, Issue:21

    Topics: Alkaloids; Crystallography, X-Ray; Models, Molecular; Molecular Structure; Pyrroles; Stereoisomerism

2010
Oroidin inhibits the activity of the multidrug resistance target Pdr5p from yeast plasma membranes.
    Journal of natural products, 2011, Feb-25, Volume: 74, Issue:2

    Topics: Animals; ATP-Binding Cassette Transporters; Cell Membrane; Drug Resistance, Multiple; Marine Biology; Molecular Structure; Porifera; Pyrroles; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins

2011
Diversity-oriented approach to pyrrole-imidazole alkaloid frameworks.
    Organic letters, 2011, Mar-18, Volume: 13, Issue:6

    Topics: Alkaloids; Amides; Animals; Cyclization; Molecular Structure; Porifera; Pyrroles

2011
New insight into marine alkaloid metabolic pathways: revisiting oroidin biosynthesis.
    Chembiochem : a European journal of chemical biology, 2011, Oct-17, Volume: 12, Issue:15

    Topics: Alkaloids; Animals; Axinella; Imidazoles; Lysine; Metabolic Networks and Pathways; Proline; Pyrroles

2011
De novo synthesis of benzosceptrin C and nagelamide H from 7-15N-oroidin: implications for pyrrole-aminoimidazole alkaloid biosynthesis.
    Journal of natural products, 2012, Apr-27, Volume: 75, Issue:4

    Topics: Agelas; Alkaloids; Animals; Caribbean Region; Imidazoles; Marine Biology; Molecular Structure; Pyrroles

2012
Palau'amine and related oroidin alkaloids dibromophakellin and dibromophakellstatin inhibit the human 20S proteasome.
    Journal of natural products, 2012, May-25, Volume: 75, Issue:5

    Topics: Alkaloids; Guanidines; HeLa Cells; Heterocyclic Compounds, 4 or More Rings; Humans; Imidazoles; Microscopy, Confocal; NF-kappa B; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrroles; Spiro Compounds; Stereoisomerism

2012
Unprecedented biomimetic homodimerization of oroidin and clathrodin marine metabolites in the presence of HMPA or phosphonate salt tweezers.
    Journal of natural products, 2013, May-24, Volume: 76, Issue:5

    Topics: Cyclization; Hempa; Imidazoles; Marine Biology; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Pyrroles; Stereoisomerism

2013
Total syntheses of oroidin, hymenidin and clathrodin.
    Organic & biomolecular chemistry, 2013, Jul-07, Volume: 11, Issue:25

    Topics: Models, Molecular; Pyrimidines; Pyrroles

2013
Synthesis and anticancer activity of focused compound libraries from the natural product lead, oroidin.
    Bioorganic & medicinal chemistry, 2014, Mar-01, Volume: 22, Issue:5

    Topics: Animals; Biological Products; Cell Proliferation; Molecular Structure; Pyrroles; Structure-Activity Relationship

2014
Antimicrobial activity of the marine alkaloids, clathrodin and oroidin, and their synthetic analogues.
    Marine drugs, 2014, Feb-14, Volume: 12, Issue:2

    Topics: Alkaloids; Animals; Anti-Bacterial Agents; Antifungal Agents; Candida albicans; Enterococcus faecalis; Escherichia coli; Microbial Sensitivity Tests; Porifera; Pyrroles; Staphylococcus aureus

2014
Structures and solution conformational dynamics of stylissamides G and H from the Bahamian sponge Stylissa caribica.
    Journal of natural products, 2014, Mar-28, Volume: 77, Issue:3

    Topics: Alkaloids; Animals; Caribbean Region; Imidazoles; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Peptides, Cyclic; Porifera; Pyrroles

2014
Inhibition of biofilm formation by conformationally constrained indole-based analogues of the marine alkaloid oroidin.
    Bioorganic & medicinal chemistry letters, 2014, Jun-01, Volume: 24, Issue:11

    Topics: Alkaloids; Anti-Bacterial Agents; Biofilms; Dose-Response Relationship, Drug; Indoles; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Structure; Pyrroles; Structure-Activity Relationship

2014
Disruption of heterotypic community development by Porphyromonas gingivalis with small molecule inhibitors.
    Molecular oral microbiology, 2014, Volume: 29, Issue:5

    Topics: Bacterial Adhesion; Bacterial Proteins; Benzimidazoles; Biofilms; Carbon-Sulfur Lyases; Fimbriae Proteins; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Imidazoles; Microbial Interactions; Microscopy, Confocal; Pili, Sex; Porphyromonas gingivalis; Pyrroles; Small Molecule Libraries; Streptococcus gordonii

2014
Agelamadins C-E, bromopyrrole alkaloids comprising oroidin and 3-hydroxykynurenine from a marine sponge Agelas sp.
    Organic letters, 2014, Oct-03, Volume: 16, Issue:19

    Topics: Agelas; Alkaloids; Animals; Anti-Infective Agents; Cryptococcus neoformans; Hydrocarbons, Brominated; Kynurenine; Microbial Sensitivity Tests; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Pyrroles

2014
Metabolomics approach to chemical diversity of the Mediterranean marine sponge Agelas oroides.
    Natural product research, 2017, Volume: 31, Issue:14

    Topics: Agelas; Alkaloids; Animals; Biological Products; Imidazoles; Metabolomics; Porifera; Pyrroles

2017
Marine alkaloid oroidin analogues with antiviral potential: A novel class of synthetic compounds targeting the cellular chaperone Hsp90.
    Chemical biology & drug design, 2017, Volume: 90, Issue:6

    Topics: Alkaloids; Animals; Antiviral Agents; Binding Sites; Cell Line; Cell Survival; Chikungunya virus; Hepacivirus; HSP90 Heat-Shock Proteins; Humans; Molecular Docking Simulation; Porifera; Protein Structure, Tertiary; Pyrroles; Virus Replication

2017
Clathrodin, hymenidin and oroidin, and their synthetic analogues as inhibitors of the voltage-gated potassium channels.
    European journal of medicinal chemistry, 2017, Oct-20, Volume: 139

    Topics: Dose-Response Relationship, Drug; Humans; Molecular Structure; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Pyrroles; Structure-Activity Relationship

2017
Bromopyrrole Alkaloids of the Sponge
    Journal of natural products, 2020, 02-28, Volume: 83, Issue:2

    Topics: Agelas; Alkaloids; Animals; Anti-Bacterial Agents; Chromobacterium; Imidazoles; Mediterranean Sea; Pseudomonas aeruginosa; Pyrroles; Quorum Sensing

2020
Total Synthesis of (±)-2-Debromohymenin via Gold-Catalyzed Intramolecular Alkyne Hydroarylation.
    Organic letters, 2020, 05-01, Volume: 22, Issue:9

    Topics: Alkynes; Azepines; Carbon Monoxide; Catalysis; Chemistry Techniques, Synthetic; Cyclization; Gold; Hydrocarbons, Brominated; Molybdenum; Pyrroles; Sesquiterpenes

2020
Inducing Acute Liver Injury in Rats via Carbon Tetrachloride (CCl4) Exposure Through an Orogastric Tube.
    Journal of visualized experiments : JoVE, 2020, 04-28, Issue:158

    Topics: Acute Disease; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Intubation, Gastrointestinal; Liver; Male; Pyrroles; Rats

2020