pyrroles has been researched along with a-582941 in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (46.15) | 29.6817 |
| 2010's | 5 (38.46) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Buccafusco, JJ; Decker, MW; Gopalakrishnan, M; Terry, AV | 1 |
| Anderson, DJ; Bitner, RS; Briggs, CA; Buccafusco, J; Bunnelle, WH; Curzon, P; Decker, MW; Frost, JM; Gopalakrishnan, M; Gronlien, JH; Gubbins, E; Li, J; Malysz, J; Markosyan, S; Marsh, K; Meyer, MD; Nikkel, AL; Radek, RJ; Robb, HM; Sullivan, JP; Timmermann, D | 1 |
| Anderson, DJ; Bitner, RS; Blomme, EA; Brackemeyer, PJ; Briggs, CA; Browman, KE; Bunnelle, WH; Bury, D; Curzon, P; Drescher, KU; Fox, GB; Frost, JM; Fryer, RM; Gopalakrishnan, M; Gronlien, JH; Gubbins, EJ; Håkerud, M; Halm, S; Harris, R; Helfrich, RJ; Kohlhaas, KL; Law, D; Malysz, J; Marsh, KC; Martin, RL; Meyer, MD; Molesky, AL; Nikkel, AL; Otte, S; Pan, L; Puttfarcken, PS; Radek, RJ; Robb, HM; Spies, E; Thorin-Hagene, K; Tietje, KR; Waring, JF; Ween, H; Xu, H | 1 |
| Hansen, HH; Hay-Schmidt, A; Martens, H; Mikkelsen, JD; Peters, D; Thomsen, MS; Timmermann, DB | 1 |
| Bitner, RS; Gopalakrishnan, M; Markosyan, S; Nikkel, AL; Otte, S; Puttfarcken, P | 1 |
| Anderson, DJ; Briggs, CA; Bunnelle, WH; Curzon, P; Dyhring, T; Gopalakrishnan, M; Grønlien, JH; Kerr, P; Malysz, J; Olsen, GM; Peters, D; Thorin-Hagene, K; Timmermann, DB; Ween, H | 1 |
| Hashimoto, K; Ishiwata, K; Nishiyama, S; Sakata, M; Toyohara, J; Tsukada, H; Wu, J | 1 |
| Christensen, DZ; Hansen, HH; Mikkelsen, JD; Thomsen, MS | 1 |
| El-Sayed, M; Mikkelsen, JD; Thomsen, MS | 1 |
| Baglietto-Vargas, D; Bitner, RS; Castello, NA; Cheng, D; Decker, MW; Esbenshade, TA; Green, KN; Kitazawa, M; LaFerla, FM; Medeiros, R | 1 |
| Arias, HR; Kos, T; Nikiforuk, A; Popik, P; Potasiewicz, A; Puia, G; Ravazzini, F | 1 |
| Aricioglu, F; Bekci, H; Cumaoglu, A; Unal, G; Yerer, MB | 1 |
| Aricioglu, F; Sirvanci, S; Unal, G | 1 |
1 review(s) available for pyrroles and a-582941
| Article | Year |
|---|---|
Preclinical characterization of A-582941: a novel alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Cognition; Humans; Nicotinic Agonists; Pyridazines; Pyrroles; Receptors, Nicotinic | 2008 |
12 other study(ies) available for pyrroles and a-582941
| Article | Year |
|---|---|
Profile of nicotinic acetylcholine receptor agonists ABT-594 and A-582941, with differential subtype selectivity, on delayed matching accuracy by young monkeys.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Azetidines; Choice Behavior; Cognition; Dose-Response Relationship, Drug; Macaca mulatta; Male; Nicotinic Agonists; Psychomotor Performance; Pyridazines; Pyridines; Pyrroles; Receptors, Nicotinic | 2007 |
Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1/2 and CREB phosphorylation pathways.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Aminoacetonitrile; Animals; Central Nervous System Agents; Cognition; Cyclic AMP Response Element-Binding Protein; Extracellular Signal-Regulated MAP Kinases; Humans; Learning; Macaca mulatta; Male; Mental Processes; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Pyridazines; Pyrroles; Rats; Receptors, Nicotinic; Signal Transduction; Treatment Outcome; Xenopus | 2007 |
The selective alpha7 nicotinic acetylcholine receptor agonist A-582941 activates immediate early genes in limbic regions of the forebrain: Differential effects in the juvenile and adult rat.
Topics: Aging; alpha7 Nicotinic Acetylcholine Receptor; Animals; Cytoskeletal Proteins; Genes, fos; Genes, Immediate-Early; Immunohistochemistry; In Situ Hybridization; Limbic System; Male; Nerve Tissue Proteins; Nicotinic Agonists; Prefrontal Cortex; Prosencephalon; Pyridazines; Pyrroles; Rats; Rats, Wistar; Receptors, Nicotinic; RNA, Messenger | 2008 |
Selective alpha7 nicotinic acetylcholine receptor activation regulates glycogen synthase kinase3beta and decreases tau phosphorylation in vivo.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Alzheimer Disease; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Immunohistochemistry; Injections, Intraperitoneal; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphorylation; Pyridazines; Pyrroles; Receptors, Nicotinic; Signal Transduction; tau Proteins | 2009 |
Role of channel activation in cognitive enhancement mediated by alpha7 nicotinic acetylcholine receptors.
Topics: Allosteric Regulation; alpha7 Nicotinic Acetylcholine Receptor; Animals; Avoidance Learning; Azabicyclo Compounds; Behavior, Animal; Cell Line; Cognition Disorders; Dose-Response Relationship, Drug; Furans; Humans; Male; Mice; Nicotinic Agonists; Oocytes; Oxadiazoles; Pyridazines; Pyrroles; Rats; Receptors, Nicotinic; Xenopus laevis | 2009 |
In vivo evaluation of alpha7 nicotinic acetylcholine receptor agonists [11C]A-582941 and [11C]A-844606 in mice and conscious monkeys.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Brain; Carbon Radioisotopes; Consciousness; Haplorhini; Male; Mice; Models, Chemical; Molecular Structure; Nicotinic Agonists; Positron-Emission Tomography; Pyridazines; Pyrroles; Radiopharmaceuticals; Receptors, Nicotinic; Tissue Distribution; Xanthones | 2010 |
Repeated administration of alpha7 nicotinic acetylcholine receptor (nAChR) agonists, but not positive allosteric modulators, increases alpha7 nAChR levels in the brain.
Topics: Allosteric Regulation; alpha7 Nicotinic Acetylcholine Receptor; Animals; Binding Sites; Brain; Bungarotoxins; Cytoskeletal Proteins; Drug Administration Schedule; Male; Nerve Tissue Proteins; Nicotinic Agonists; Proto-Oncogene Proteins c-fos; Pyridazines; Pyrroles; Rats; Rats, Wistar; Receptors, Nicotinic; Signal Transduction | 2010 |
Differential immediate and sustained memory enhancing effects of alpha7 nicotinic receptor agonists and allosteric modulators in rats.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; GPI-Linked Proteins; In Situ Hybridization; Intracellular Signaling Peptides and Proteins; Isoxazoles; Male; Memory; Memory, Short-Term; Nicotinic Agonists; Nicotinic Antagonists; Phenylurea Compounds; Pyridazines; Pyrroles; Rats; Rats, Wistar; Receptors, Nicotinic; RNA, Messenger | 2011 |
α7 Nicotinic receptor agonist enhances cognition in aged 3xTg-AD mice with robust plaques and tangles.
Topics: Aging; alpha7 Nicotinic Acetylcholine Receptor; Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Cognition; Humans; Inflammation; Male; Memory; Mice; Mice, Transgenic; Neurofibrillary Tangles; Nootropic Agents; Phosphorylation; Plaque, Amyloid; Pyridazines; Pyrroles; tau Proteins | 2014 |
Pro-cognitive activity in rats of 3-furan-2-yl-N-p-tolyl-acrylamide, a positive allosteric modulator of the α7 nicotinic acetylcholine receptor.
Topics: Acrylamides; Allosteric Regulation; alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzylidene Compounds; Cell Line, Tumor; Cognition; Furans; Humans; Male; Nicotinic Agonists; Pyridazines; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Scopolamine | 2015 |
Alpha 7 nicotinic receptor agonist and positive allosteric modulators improved social and molecular deficits of MK-801 model of schizophrenia in rats.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Allosteric Regulation; alpha7 Nicotinic Acetylcholine Receptor; Animals; Avoidance Learning; Clozapine; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Disease Models, Animal; Dizocilpine Maleate; Glycogen Synthase Kinase 3 beta; Isoxazoles; Male; Phenylurea Compounds; Prefrontal Cortex; Proto-Oncogene Proteins c-akt; Pyridazines; Pyrroles; Rats; Rats, Wistar; Schizophrenia; Signal Transduction; Social Interaction; Treatment Outcome | 2020 |
α7 nicotinic receptor agonist and positive allosteric modulators differently improved schizophrenia-like cognitive deficits in male rats.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Antipsychotic Agents; Behavior, Animal; Cognitive Dysfunction; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hippocampus; Isoxazoles; Male; Nicotinic Agonists; Phenylurea Compounds; Pyridazines; Pyrroles; Rats; Rats, Wistar; Recognition, Psychology; Schizophrenia | 2021 |