pyrroles has been researched along with a 419259 in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Choi, HJ; Kamens, J; Schreiner, SJ; Smithgall, TE; Wilson, MB | 1 |
| Donato, NJ; Pene-Dumitrescu, T; Peterson, LF; Smithgall, TE | 1 |
| Meyn, MA; Smithgall, TE; Zhang, X | 1 |
| Cho, Y; Je, DW; Ji, YG; Lee, DH; O, YM | 1 |
| Hartnett, C; Schatten, G; Simerly, C; Smithgall, TE; Zhang, X | 1 |
| Hayashi, M; Kim, Y; Nakashima, T; Ono, T; Takayanagi, H; Yoda, T | 1 |
| Cooper, VS; Patel, RK; Shen, K; Smithgall, TE; Snyder, D; Weir, MC | 1 |
7 other study(ies) available for pyrroles and a 419259
| Article | Year |
|---|---|
Selective pyrrolo-pyrimidine inhibitors reveal a necessary role for Src family kinases in Bcr-Abl signal transduction and oncogenesis.
Topics: Apoptosis; Cell Division; Cell Transformation, Neoplastic; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Fusion Proteins, bcr-abl; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; K562 Cells; Leukemia, Erythroblastic, Acute; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Milk Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Monocytes; Neoplasm Proteins; Phosphorylation; Protein Processing, Post-Translational; Pyrimidines; Pyrroles; Signal Transduction; src-Family Kinases; STAT5 Transcription Factor; Trans-Activators; Tumor Cells, Cultured | 2002 |
An inhibitor-resistant mutant of Hck protects CML cells against the antiproliferative and apoptotic effects of the broad-spectrum Src family kinase inhibitor A-419259.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Proliferation; Drug Resistance, Neoplasm; Extracellular Signal-Regulated MAP Kinases; Fusion Proteins, bcr-abl; Humans; Insecta; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mutation; Proto-Oncogene Proteins c-hck; Pyrimidines; Pyrroles; src-Family Kinases | 2008 |
c-Yes tyrosine kinase is a potent suppressor of ES cell differentiation and antagonizes the actions of its closest phylogenetic relative, c-Src.
Topics: Animals; Cell Differentiation; Cell Line; CSK Tyrosine-Protein Kinase; Embryonic Stem Cells; Gene Expression Regulation, Enzymologic; Mice; Mutation; Phylogeny; Proto-Oncogene Proteins c-yes; Pyrimidines; Pyrroles; Rats; src-Family Kinases | 2014 |
The inhibition of SRC family kinase suppresses pancreatic cancer cell proliferation, migration, and invasion.
Topics: Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Humans; Neoplasm Invasiveness; Neoplasm Proteins; Pancreatic Neoplasms; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-fyn; Proto-Oncogene Proteins c-hck; Proto-Oncogene Proteins c-yes; Proto-Oncogene Proteins pp60(c-src); Pyrimidines; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; src-Family Kinases | 2014 |
Src-family tyrosine kinase activities are essential for differentiation of human embryonic stem cells.
Topics: Antigens, Surface; Cell Differentiation; Cell Line; Embryoid Bodies; Embryonic Stem Cells; Gene Expression Regulation; Humans; Hydrazines; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Protein Kinase Inhibitors; Proteoglycans; Pyrazoles; Pyrimidines; Pyrroles; RNA, Messenger; src-Family Kinases | 2014 |
Suppression of hematopoietic cell kinase ameliorates the bone destruction associated with inflammation.
Topics: Animals; Blotting, Western; Bone Resorption; Cell Differentiation; Cells, Cultured; Gene Expression Regulation; Inflammation; Mice; Mice, Inbred BALB C; Osteoclasts; Osteogenesis; Proto-Oncogene Proteins c-hck; Pyrimidines; Pyrroles; RNA; src-Family Kinases | 2020 |
Expression of myeloid Src-family kinases is associated with poor prognosis in AML and influences Flt3-ITD kinase inhibitor acquired resistance.
Topics: Amino Acid Substitution; Cell Line, Tumor; Drug Resistance, Neoplasm; Exome Sequencing; fms-Like Tyrosine Kinase 3; Gene Expression Regulation, Developmental; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid, Acute; Mutation, Missense; Prognosis; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-hck; Pyrimidines; Pyrroles; src-Family Kinases | 2019 |