Page last updated: 2024-08-16

propofol and zidovudine

propofol has been researched along with zidovudine in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (42.11)29.6817
2010's11 (57.89)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Chang, TK; Ensom, MH; Kiang, TK1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Fukami, T; Kato, Y; Nakajima, M; Oda, S; Yokoi, T1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Kamimura, H; Mano, Y; Usui, T1
Deng, JP; Fang, ZZ; Hu, CM; Li, G; Li, HR; Tu, YY; Wang, L; Yao, JJ; Yuan, J; Zhang, YS1
Barter, Z; Gibson, CR; Lai, E; Lu, P; Maciolek, C; Nicoll-Griffith, DA; Rowland-Yeo, K; Stroh, M; Wudarski, C1
Chen, JX; Fan, XR; Hong, M; Huang, T; Liu, X; Sun, HZ; Sun, XY; Yu, ZW; Zeng, J1
Ando, A; Higashi, E; Iwano, S; Miyamoto, Y; Murayama, N; Yamazaki, H1
Li, FY; Liu, L; Liu, ZQ; Lu, L; Peng, XJ; Qi, XX; Shi, J; Wang, Y; Zhou, FY; Zhou, J1
Chau, N; Fallon, JK; Knights, KM; Miners, JO; Smith, PC; Spencer, SM1

Reviews

3 review(s) available for propofol and zidovudine

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for propofol and zidovudine

ArticleYear
Using human recombinant UDP-glucuronosyltransferase isoforms and a relative activity factor approach to model total body clearance of laropiprant (MK-0524) in humans.
    Xenobiotica; the fate of foreign compounds in biological systems, 2013, Volume: 43, Issue:12

    Topics: Administration, Intravenous; Adult; Estradiol; Female; Glucuronides; Glucuronosyltransferase; Humans; Indoles; Isoenzymes; Kidney; Kinetics; Male; Metabolic Clearance Rate; Microsomes, Liver; Propofol; Recombinant Proteins; Substrate Specificity; UDP-Glucuronosyltransferase 1A9; Young Adult; Zidovudine

2013

Other Studies

15 other study(ies) available for propofol and zidovudine

ArticleYear
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Human UDP-glucuronosyltransferase isoforms involved in haloperidol glucuronidation and quantitative estimation of their contribution.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2

    Topics: Animals; Antipsychotic Agents; Enzyme Inhibitors; Glucuronides; Glucuronosyltransferase; Haloperidol; Humans; Isoenzymes; Kinetics; Male; Microsomes, Liver; Molecular Structure; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Species Specificity; Substrate Specificity; UDP-Glucuronosyltransferase 1A9; Uridine Diphosphate Glucuronic Acid

2012
Contribution of UDP-glucuronosyltransferases 1A9 and 2B7 to the glucuronidation of indomethacin in the human liver.
    European journal of clinical pharmacology, 2007, Volume: 63, Issue:3

    Topics: Glucuronides; Glucuronosyltransferase; Humans; Indomethacin; Liver; Mass Spectrometry; Morphine; Propofol; UDP-Glucuronosyltransferase 1A9; Zidovudine

2007
Gossypol exhibits a strong influence towards UDP-glucuronosyltransferase (UGT) 1A1, 1A9 and 2B7-mediated metabolism of xenobiotics and endogenous substances.
    Molecules (Basel, Switzerland), 2012, Apr-27, Volume: 17, Issue:5

    Topics: Enzyme Inhibitors; Estradiol; Glucuronides; Glucuronosyltransferase; Gossypol; Humans; Isoenzymes; Kinetics; Microsomes, Liver; Propofol; Substrate Specificity; Uridine Diphosphate Glucuronic Acid; Xenobiotics; Zidovudine

2012
Arbidol exhibits strong inhibition towards UDP-glucuronosyltransferase (UGT) 1A9 and 2B7.
    Die Pharmazie, 2013, Volume: 68, Issue:12

    Topics: Anesthetics, Intravenous; Anti-HIV Agents; Antiviral Agents; Area Under Curve; Glucuronides; Glucuronosyltransferase; Humans; Indicators and Reagents; Indoles; Kinetics; Propofol; UDP-Glucuronosyltransferase 1A9; Zidovudine

2013
Hepatic microsomal UDP-glucuronosyltransferase (UGT) activities in the microminipig.
    Biopharmaceutics & drug disposition, 2014, Volume: 35, Issue:6

    Topics: Adult; Aged; Animals; Chromatography, Liquid; Dogs; Estradiol; Female; Glucuronides; Glucuronosyltransferase; Humans; Imipramine; Macaca fascicularis; Male; Mice, Inbred ICR; Microsomes, Liver; Middle Aged; Morphine; Propofol; Rats, Sprague-Dawley; Serotonin; Species Specificity; Swine; Swine, Miniature; Tandem Mass Spectrometry; Young Adult; Zidovudine

2014
Drug-Metabolizing Activity, Protein and Gene Expression of UDP-Glucuronosyltransferases Are Significantly Altered in Hepatocellular Carcinoma Patients.
    PloS one, 2015, Volume: 10, Issue:5

    Topics: Adult; Camptothecin; Carcinoma, Hepatocellular; Genistein; Glucuronosyltransferase; Humans; Inactivation, Metabolic; Irinotecan; Liver Neoplasms; Male; Metabolic Clearance Rate; Microsomes, Liver; Middle Aged; Propofol; Tamoxifen; Zidovudine

2015
Scaling factors for the in vitro-in vivo extrapolation (IV-IVE) of renal drug and xenobiotic glucuronidation clearance.
    British journal of clinical pharmacology, 2016, Volume: 81, Issue:6

    Topics: Deferiprone; Glucuronosyltransferase; Kidney; Microsomes; Microsomes, Liver; Morphine; Propofol; Proteins; Pyridones; UDP-Glucuronosyltransferase 1A9; Zidovudine

2016
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