Page last updated: 2024-08-16

prazosin and mannitol

prazosin has been researched along with mannitol in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19902 (20.00)18.7374
1990's0 (0.00)18.2507
2000's4 (40.00)29.6817
2010's4 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Ondrejka, P; Pechán, J; Veres, I1
Biollaz, B; Biollaz, J; Gavras, H; Gavras, I; Kohlmann, O1
Antunes, VR; Murphy, D; Paton, JF; Pickering, AE; Yao, ST1

Reviews

1 review(s) available for prazosin and mannitol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for prazosin and mannitol

ArticleYear
Haemodynamic effect of prazosin during hyperosmolar mannitol load in essential hypertension.
    Cor et vasa, 1989, Volume: 31, Issue:6

    Topics: Adolescent; Adult; Blood Pressure; Blood Volume; Cardiac Output; Female; Heart Rate; Humans; Hypertension; Male; Mannitol; Microcirculation; Middle Aged; Muscles; Osmolar Concentration; Prazosin; Vascular Resistance

1989

Other Studies

8 other study(ies) available for prazosin and mannitol

ArticleYear
Rational use of in vitro P-glycoprotein assays in drug discovery.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera

2001
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Sodium chloride-induced partial inhibition in vivo of alpha 2-adrenoceptor agonist function.
    Journal of hypertension, 1985, Volume: 3, Issue:3

    Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Clonidine; Male; Mannitol; Nephrectomy; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sodium Chloride; Yohimbine

1985
A spinal vasopressinergic mechanism mediates hyperosmolality-induced sympathoexcitation.
    The Journal of physiology, 2006, Oct-15, Volume: 576, Issue:Pt 2

    Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Evoked Potentials; Gene Expression Regulation; Male; Mannitol; Osmolar Concentration; Paraventricular Hypothalamic Nucleus; Prazosin; Rats; Rats, Wistar; Receptors, Vasopressin; Saline Solution, Hypertonic; Spinal Cord; Spinal Nerves; Sympathetic Nervous System; Vasopressins

2006