oxazolidin-2-one and pyrazines
oxazolidin-2-one has been researched along with pyrazines in 13 studies
Research
Studies (13)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (7.69) | 29.6817 |
2010's | 11 (84.62) | 24.3611 |
2020's | 1 (7.69) | 2.80 |
Authors
Authors | Studies |
---|---|
Chamberlin, AR; Habay, SA; Okamura, N; Reinscheid, RK; Zeng, J | 1 |
Clark, SD; Reinscheid, RK; Tran, HT; Zeng, J | 1 |
Calo', G; Camarda, V; Ciccocioppo, R; Cifani, C; Filaferro, M; Guerrini, R; Pela', M; Reinscheid, RK; Rizzi, A; Ruggieri, V; Ruzza, C; Salvadori, S; Trapella, C; Vitale, G | 1 |
Bertolasi, V; Calo, G; Camarda, V; Cavazzini, A; Costa, V; Del Zoppo, L; Guerrini, R; Pela, M; Reinscheid, RK; Ruzza, C; Salvadori, S; Trapella, C | 1 |
Buell, DR; Dine, J; Eder, M; Herrmann, L; Holsboer, F; Ionescu, IA; Landgraf, R; Schmidt, U; Yen, YC | 1 |
Deschamps, JR; Fennell, T; Garau, C; Gilmour, B; Graf, T; Hassler, C; Reinscheid, RK; Runyon, SP; Snyder, R; Zhang, Y | 1 |
Chen, WM; Chen, Y; Huangfu, DS; Lin, J; Ruan, ZX; Sun, PH; Wang, F | 1 |
Asth, L; Gavioli, EC; Guerrini, R; Ruzza, C; Trapella, C | 1 |
Hashimoto, K; Ishima, T; Iyo, M; Oda, Y; Okamura, N; Shirayama, Y | 1 |
Baillie, TA; Cyrus Khojasteh, S; Dalvie, D; Rietjens, IM | 1 |
Ensho, T; Murakami, N; Nakahara, K; Suzuki, Y | 1 |
Gu, Y; Ma, T; Pusch, S; von Deimling, A; Xu, Y; Yang, L; Zha, X; Zhu, Q; Zou, F | 1 |
Cai, CC; Chen, HL; Cong, CY; Cui, GF; Dong, CY; Hou, YP; Kong, XP; Li, J; Ren, YL; Shao, YF; Wang, C; Xie, JF; Xin, L | 1 |
Reviews
1 review(s) available for oxazolidin-2-one and pyrazines
Article | Year |
---|---|
Biotransformation and bioactivation reactions - 2015 literature highlights.
Topics: Acetaminophen; Allylbenzene Derivatives; Aniline Compounds; Animals; Anisoles; Benzbromarone; Biotransformation; Humans; Imidazoles; Niacinamide; Nitroimidazoles; Nitrosamines; Oxazoles; Oxazolidinones; Peroxides; Pyrazines; Pyrazoles; Pyridazines; Pyridines; Pyridones; Pyrimidinones; Thiophenes; Triazoles | 2016 |
Other Studies
12 other study(ies) available for oxazolidin-2-one and pyrazines
Article | Year |
---|---|
Synthesis and pharmacological in vitro and in vivo profile of 3-oxo-1,1-diphenyl-tetrahydro-oxazolo[3,4-a]pyrazine-7-carboxylic acid 4-fluoro-benzylamide (SHA 68), a selective antagonist of the neuropeptide S receptor.
Topics: Animals; Cell Line; Humans; Male; Mice; Mice, Inbred C57BL; Motor Activity; Neuropeptides; Oxazolidinones; Pyrazines; Receptors, G-Protein-Coupled | 2008 |
Importance of extracellular loop one of the neuropeptide S receptor for biogenesis and function.
Topics: Amino Acid Sequence; Animals; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxazolidinones; Protein Processing, Post-Translational; Protein Structure, Secondary; Pyrazines; Radioligand Assay; Receptors, G-Protein-Coupled; Sequence Alignment; Structure-Activity Relationship | 2010 |
Further studies on the pharmacological profile of the neuropeptide S receptor antagonist SHA 68.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Caffeine; Cell Line; Eating; Exploratory Behavior; Humans; Male; Maze Learning; Mice; Motor Activity; Neuropeptides; Oxazolidinones; Pyrazines; Rats; Receptors, Neuropeptide | 2010 |
Synthesis and separation of the enantiomers of the neuropeptide S receptor antagonist (9R/S)-3-oxo-1,1-diphenyl-tetrahydro-oxazolo[3,4-a]pyrazine-7-carboxylic acid 4-fluoro-benzylamide (SHA 68).
Topics: Crystallography, X-Ray; Magnetic Resonance Spectroscopy; Models, Molecular; Oxazolidinones; Pyrazines; Receptors, Neuropeptide; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism | 2011 |
Intranasally administered neuropeptide S (NPS) exerts anxiolytic effects following internalization into NPS receptor-expressing neurons.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; CA1 Region, Hippocampal; Carbocyanines; Cell Line, Transformed; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Electrophysiology; Evoked Potentials; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Green Fluorescent Proteins; Humans; In Vitro Techniques; Intravitreal Injections; Male; Maze Learning; Mice; Mice, Inbred C57BL; Neurofilament Proteins; Neurons; Neuropeptides; Oxazolidinones; Protein Transport; Pyrazines; Receptors, AMPA; Receptors, Neuropeptide; Rhodamines; RNA, Messenger; Synapsins; Transfection | 2012 |
Identification of neuropeptide S antagonists: structure-activity relationship studies, X-ray crystallography, and in vivo evaluation.
Topics: Animals; CHO Cells; Cricetulus; Crystallography, X-Ray; Humans; Hydrophobic and Hydrophilic Interactions; Isomerism; Male; Mice, Inbred C57BL; Molecular Structure; Motor Activity; Neuropeptides; Neurotransmitter Agents; Oxazolidinones; Pyrazines; Receptors, Neuropeptide; Solubility; Structure-Activity Relationship; Water | 2014 |
Novel Oxazolidinone Antibacterial Analogues with a Substituted Ligustrazine C-ring Unit.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Chemistry Techniques, Synthetic; Drug Evaluation, Preclinical; Gram-Positive Bacteria; Interleukin-6; Lipopolysaccharides; Macrophages; Mice; Microbial Sensitivity Tests; Nitric Oxide; Oxazolidinones; Pyrazines; Structure-Activity Relationship; Tumor Necrosis Factor-alpha | 2015 |
Neuropeptide S reduces mouse aggressiveness in the resident/intruder test through selective activation of the neuropeptide S receptor.
Topics: Aggression; Animals; Central Nervous System Agents; Dose-Response Relationship, Drug; Male; Mice; Mice, Knockout; Neuropeptides; Oxazolidinones; Phenotype; Psychotropic Drugs; Pyrazines; Random Allocation; Receptors, Neuropeptide; Valproic Acid | 2015 |
Opposite roles for neuropeptide S in the nucleus accumbens and bed nucleus of the stria terminalis in learned helplessness rats.
Topics: Animals; Antidepressive Agents; Avoidance Learning; Depressive Disorder; Disease Models, Animal; Helplessness, Learned; Male; Memory; Motor Activity; Neuropeptides; Nucleus Accumbens; Oxazolidinones; Pyrazines; Rats, Sprague-Dawley; Receptors, Neuropeptide; Septal Nuclei | 2015 |
Neuropeptide S increases motor activity and thermogenesis in the rat through sympathetic activation.
Topics: Adrenergic beta-Antagonists; Animals; Brain Stem; Circadian Rhythm; Corticosterone; Energy Metabolism; Epinephrine; Hypothalamus; Male; Motor Activity; Neuropeptides; Oxazolidinones; Pyrazines; Rats, Wistar; Receptors, Neuropeptide; RNA, Messenger; Sympathetic Nervous System; Thermogenesis | 2017 |
Design, synthesis and biological activity of 3-pyrazine-2-yl-oxazolidin-2-ones as novel, potent and selective inhibitors of mutant isocitrate dehydrogenase 1.
Topics: Cell Survival; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; HEK293 Cells; Humans; Isocitrate Dehydrogenase; Molecular Docking Simulation; Molecular Structure; Mutation; Oxazolidinones; Pyrazines; Structure-Activity Relationship | 2017 |
Neuropeptide S Displays as a Key Neuromodulator in Olfactory Spatial Memory.
Topics: Animals; Infusions, Intraventricular; Male; Mice; Mice, Inbred C57BL; Neuropeptides; Neurotransmitter Agents; Olfactory Perception; Oxazolidinones; Pyrazines; Receptors, Neuropeptide; Spatial Memory | 2020 |