nnc 711 has been researched along with baclofen in 8 studies
| Studies (nnc 711) | Trials (nnc 711) | Recent Studies (post-2010) (nnc 711) | Studies (baclofen) | Trials (baclofen) | Recent Studies (post-2010) (baclofen) |
|---|---|---|---|---|---|
| 112 | 0 | 21 | 6,017 | 372 | 1,535 |
| Protein | Taxonomy | nnc 711 (IC50) | baclofen (IC50) |
|---|---|---|---|
| Gamma-aminobutyric acid type B receptor subunit 2 | Homo sapiens (human) | 0.05 | |
| Gamma-aminobutyric acid type B receptor subunit 2 | Rattus norvegicus (Norway rat) | 0.2762 | |
| Gamma-aminobutyric acid type B receptor subunit 1 | Homo sapiens (human) | 0.05 | |
| Gamma-aminobutyric acid type B receptor subunit 1 | Rattus norvegicus (Norway rat) | 0.2762 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Dalvi, A; Rodgers, RJ | 1 |
| Kombian, SB; Mouginot, D; Pittman, QJ | 1 |
| Blythin, DJ; Kerr, DI; Marino, V; Ong, J; Parker, DA | 1 |
| Marino, V; Nassery, K; Parker, DA | 1 |
| Dvorzhak, A; Grantyn, R; Kirischuk, S; Kirmse, K | 1 |
| Dobbs, L; Holstein, SE; Phillips, TJ | 1 |
| Chen, CC; Cheng, SJ; Lin, CC; Lu, HC; Min, MY; Wang, HY; Wu, Y; Yang, HW | 1 |
8 other study(ies) available for nnc 711 and baclofen
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
GABAergic influences on plus-maze behaviour in mice.
Topics: Animals; Baclofen; Behavior, Animal; Bicuculline; Diazepam; GABA Modulators; Male; Mice; Mice, Inbred DBA; Muscimol; Nipecotic Acids; Oximes; Picrotoxin; Valproic Acid | 1996 |
Activation of presynaptic GABAB receptors inhibits evoked IPSCs in rat magnocellular neurons in vitro.
Topics: Animals; Baclofen; Evoked Potentials; Excitatory Postsynaptic Potentials; GABA Antagonists; Hypothalamus; In Vitro Techniques; Membrane Potentials; Neurons; Nipecotic Acids; Organophosphorus Compounds; Oximes; Patch-Clamp Techniques; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, GABA-B; Supraoptic Nucleus; Virulence Factors, Bordetella | 1998 |
Antagonism of GABA(B) receptors by morpholino-2-acetic acid derivatives Sch 54679 and Sch 51324 in rat brain.
Topics: Animals; Baclofen; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Morpholines; Neocortex; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Oximes; Rats; Rats, Sprague-Dawley; Tritium | 1999 |
Uptake and release of [(3)H]GABA in human dental pulp.
Topics: Adult; Autoreceptors; Baclofen; Dental Pulp; Electric Stimulation; Female; GABA Agents; GABA Agonists; GABA Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Male; Morpholines; Nipecotic Acids; Oximes; Radiopharmaceuticals; Receptors, GABA; Time Factors; Tritium | 2007 |
GABA transporter 1 tunes GABAergic synaptic transmission at output neurons of the mouse neostriatum.
Topics: Action Potentials; Animals; Animals, Newborn; Baclofen; Bicuculline; Electric Impedance; Electric Stimulation; Electrophysiology; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; In Vitro Techniques; Membrane Potentials; Mice; Mice, Inbred C57BL; Neostriatum; Neurons; Nipecotic Acids; Oximes; Patch-Clamp Techniques; Phosphinic Acids; Presynaptic Terminals; Propanolamines; Pyridazines; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Synaptic Transmission; Tetrodotoxin | 2008 |
Attenuation of the stimulant response to ethanol is associated with enhanced ataxia for a GABA, but not a GABA, receptor agonist.
Topics: Animals; Ataxia; Baclofen; Dose-Response Relationship, Drug; Ethanol; GABA-A Receptor Agonists; GABA-B Receptor Agonists; Male; Mice; Mice, Mutant Strains; Motor Activity; Muscimol; Nipecotic Acids; Oximes; Receptors, GABA-A; Receptors, GABA-B | 2009 |
GABAB receptor-mediated tonic inhibition of noradrenergic A7 neurons in the rat.
Topics: Analysis of Variance; Animals; Anisoles; Baclofen; Barium; Bee Venoms; Dopamine beta-Hydroxylase; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GABA Antagonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Gene Expression Regulation; In Vitro Techniques; Lysine; Male; Morpholines; Neural Inhibition; Neurons; Nipecotic Acids; Norepinephrine; Organophosphorus Compounds; Oximes; Patch-Clamp Techniques; Pons; Potassium Channel Blockers; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; RNA, Messenger | 2011 |