Page last updated: 2024-09-04

ml-3000 and riluzole

ml-3000 has been researched along with riluzole in 2 studies

Compound Research Comparison

Studies (ml-3000)	Trials (ml-3000)	Recent Studies (post-2010) (ml-3000)	Studies (riluzole)	Trials (riluzole)	Recent Studies (post-2010) (riluzole)
130	9	56	1,244	153	572

Protein Interaction Comparison

Protein	Taxonomy	riluzole (IC50)
Sodium channel protein type 2 subunit alpha	Rattus norvegicus (Norway rat)	4.73
Cytochrome P450 1A2	Homo sapiens (human)	10
Aldo-keto reductase family 1 member B1	Rattus norvegicus (Norway rat)	1.733
Sodium-dependent noradrenaline transporter	Homo sapiens (human)	1.733

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ	1
Dulin, JN; Grill, RJ; Moore, ML	1

Other Studies

2 other study(ies) available for ml-3000 and riluzole

Article	Year
Identification of potent Yes1 kinase inhibitors using a library screening approach. Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15 Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship	2013
The dual cyclooxygenase/5-lipoxygenase inhibitor licofelone attenuates p-glycoprotein-mediated drug resistance in the injured spinal cord. Journal of neurotrauma, 2013, Feb-01, Volume: 30, Issue:3 Topics: Animals; Arachidonate 5-Lipoxygenase; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Disease Models, Animal; Drug Resistance; Enzyme Inhibitors; Gene Knockout Techniques; Male; Mice; Mice, Knockout; Neuroprotective Agents; Prostaglandin-Endoperoxide Synthases; Pyrroles; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Recovery of Function; Riluzole; Spinal Cord Injuries; Tissue Array Analysis	2013

Article

Year

Identification of potent Yes1 kinase inhibitors using a library screening approach.

Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013

The dual cyclooxygenase/5-lipoxygenase inhibitor licofelone attenuates p-glycoprotein-mediated drug resistance in the injured spinal cord.

Journal of neurotrauma, 2013, Feb-01, Volume: 30, Issue:3

Topics: Animals; Arachidonate 5-Lipoxygenase; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Disease Models, Animal; Drug Resistance; Enzyme Inhibitors; Gene Knockout Techniques; Male; Mice; Mice, Knockout; Neuroprotective Agents; Prostaglandin-Endoperoxide Synthases; Pyrroles; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Recovery of Function; Riluzole; Spinal Cord Injuries; Tissue Array Analysis

2013