mk 0663 has been researched along with parecoxib in 10 studies
| Studies (mk 0663) | Trials (mk 0663) | Recent Studies (post-2010) (mk 0663) | Studies (parecoxib) | Trials (parecoxib) | Recent Studies (post-2010) (parecoxib) |
|---|---|---|---|---|---|
| 549 | 173 | 265 | 436 | 186 | 229 |
| Protein | Taxonomy | mk 0663 (IC50) | parecoxib (IC50) |
|---|---|---|---|
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.005 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hardy, KJ; McMurray, RW | 1 |
| Frölich, JC; Stichtenoth, DO | 1 |
| Cryer, B | 1 |
| Benoit, V; de Leval, X; Dogné, JM; Frederich, M; Julémont, F; Pirotte, B | 1 |
| Bhatia, S; Seedher, N | 1 |
| Bhushan, A; Kaur, P; Mir, R; Sharma, S; Singh, N; Singh, TP; Sinha, M; Srinivasan, A; Vikram, G | 1 |
| Elliott, WJ | 1 |
| Dahl, V; Raeder, JC; Spreng, UJ; Waage, M | 1 |
| Dávila, I; González, A; Laffond, E; Moreno, E; Muñoz-Bellido, F; Ponce, V | 1 |
| Katchamart, W; Suwanawiboon, B; Tantayakom, P; Teerawattananon, C | 1 |
6 review(s) available for mk 0663 and parecoxib
| Article | Year |
|---|---|
Cox-2 inhibitors: today and tomorrow.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Clinical Trials as Topic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Etoricoxib; Humans; Isoenzymes; Isoxazoles; Lactones; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Pyridines; Research; Sulfonamides; Sulfones | 2002 |
The second generation of COX-2 inhibitors: what advantages do the newest offer?
Topics: Clinical Trials as Topic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Drug Interactions; Etoricoxib; Humans; Isoenzymes; Isoxazoles; Membrane Proteins; Organic Chemicals; Prostaglandin-Endoperoxide Synthases; Pyridines; Sulfonamides; Sulfones | 2003 |
The role of cyclooxygenase selective inhibitors in the gastrointestinal tract.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Digestive System; Etoricoxib; Humans; Isoxazoles; Pyridines; Sulfonamides; Sulfones; Ulcer | 2003 |
First and second generations of COX-2 selective inhibitors.
Topics: Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Etoricoxib; Gastrointestinal Diseases; Humans; Isoenzymes; Isoxazoles; Lactones; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Pyridines; Sulfonamides; Sulfones | 2004 |
Do the blood pressure effects of nonsteroidal antiinflammatory drugs influence cardiovascular morbidity and mortality?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Humans; Hypertension; Isoxazoles; Lactones; Pyrazoles; Pyridines; Risk; Risk Factors; Sulfonamides; Sulfones | 2010 |
Risk of perioperative bleeding related to highly selective cyclooxygenase-2 inhibitors: A systematic review and meta-analysis.
Topics: Blood Loss, Surgical; Celecoxib; Cyclooxygenase 2 Inhibitors; Etoricoxib; Humans; Isoxazoles; Postoperative Hemorrhage; Pyridines; Risk Factors; Sulfones | 2017 |
1 trial(s) available for mk 0663 and parecoxib
| Article | Year |
|---|---|
Short stay and less pain after ambulatory anterior cruciate ligament (ACL) repair: COX-2 inhibitor versus glucocorticoid versus both combined.
Topics: Adolescent; Adult; Ambulatory Surgical Procedures; Analysis of Variance; Anterior Cruciate Ligament Reconstruction; Blood Pressure; Cyclooxygenase 2 Inhibitors; Dexamethasone; Double-Blind Method; Drug Therapy, Combination; Endpoint Determination; Etoricoxib; Female; Glucocorticoids; Humans; Injections, Intravenous; Isoxazoles; Length of Stay; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Pyridines; Sample Size; Sulfones; Young Adult | 2012 |
3 other study(ies) available for mk 0663 and parecoxib
| Article | Year |
|---|---|
Interaction of non-steroidal anti-inflammatory drugs, etoricoxib and parecoxib sodium, with human serum albumin studied by fluorescence spectroscopy.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Drug Interactions; Etoricoxib; Humans; Isoxazoles; Pyridines; Serum Albumin; Spectrometry, Fluorescence; Sulfones; Thermodynamics | 2006 |
Structural and binding studies of C-terminal half (C-lobe) of lactoferrin protein with COX-2-specific non-steroidal anti-inflammatory drugs (NSAIDs).
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Cattle; Crystallography, X-Ray; Cyclooxygenase 2 Inhibitors; Etoricoxib; In Vitro Techniques; Isoxazoles; Lactoferrin; Models, Molecular; Peptide Fragments; Protein Binding; Protein Conformation; Pyridines; Sulfonamides; Sulfones | 2010 |
Fixed drug eruption caused by etoricoxib with tolerance to celecoxib and parecoxib.
Topics: Aged; Arm; Celecoxib; Cyclooxygenase 2 Inhibitors; Drug Eruptions; Etoricoxib; Female; Humans; Isoxazoles; Leg Dermatoses; Low Back Pain; Patch Tests; Pyrazoles; Pyridines; Sulfonamides; Sulfones | 2012 |