Page last updated: 2024-08-17

lactose and albuterol

lactose has been researched along with albuterol in 117 studies

Research

Studies (117)

TimeframeStudies, this research(%)All Research%
pre-19902 (1.71)18.7374
1990's7 (5.98)18.2507
2000's61 (52.14)29.6817
2010's37 (31.62)24.3611
2020's10 (8.55)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chung, M; Gural, R; Patrick, JE; Powell, ML; Radwanski, E; Symchowicz, SS; Weisberger, M1
Godfrey, S; Silverman, M1
Davis, SS; Purewal, TS; Sidhu, BK; Washington, C1
Bower, C; Purewal, TS; Washington, C2
Marriott, C; Martin, GP; Srichana, T2
Carter, PA; Fletcher, EJ; Rowley, G; Stylianopoulos, V1
Ghoush, AA; Marriott, C; Martin, GP; Tee, SK; Zeng, XM1
Larhrib, H; Marriott, C; Martin, GP; Pritchard, J; Zeng, XM1
Brain, A; Marriott, C; Martin, GP; Srichana, T1
Chan, LW; Heng, PW; Lim, LT2
Marriott, C; Martin, GP; Pritchard, J; Zeng, XM2
Marriott, C; Martin, GP; Tee, SK; Zeng, XM1
Marriott, C; Martin, GP; Pritchard, J1
Srichana, T; Suedee, R1
Danjo, K; Hayakawa, Y; Iida, K; Leuenberger, H; Okamoto, H1
Ebbens, SJ; Eve, JK; Luk, SY; Patel, N; Roberts, CJ1
Edge, S; Price, R; Staniforth, JN; Young, PM1
Srichana, T; Srisudjai, P; Suedee, R1
Larhrib, H; Marriott, C; Martin, GP; Prime, D2
Danjo, K; Hayakawa, Y; Iida, K; Luenbergerb, H; Okamoto, H1
Danjo, K; Hayakawa, Y; Iida, K; Luenberger, H; Okamoto, H2
Hartley, P; Islam, N; Larson, I; Stewart, P3
Bardina, L; Beyer, K; Nowak-Wegrzyn, A; Sampson, HA; Shapiro, GG1
Corrigan, DO; Corrigan, OI; Healy, AM2
Finlay, WH; Lange, CF; Wang, Z1
Clark, A; Palakodaty, S; Schiavone, H; Tzannis, ST; York, P1
Danjo, K; Iida, K; Inagaki, Y; Luenberger, H; Okamoto, H; Todo, H1
Begat, P; Morton, DA; Price, R; Staniforth, JN2
Booth, J; Burnett, DJ; Thielmann, F1
Danjo, K; Iida, K; Leuenberger, H; Okamoto, H; Todo, H1
Chow, AH; Shekunov, BY; Tong, HH; York, P1
Edge, S; Jones, M; Price, R; Traini, D; Young, PM1
Kammelar, R; Markefka, P; Steckel, H; teWierik, H1
de Boer, AH; Frijlink, HW; Gjaltema, D; Goede, J; Hagedoorn, P1
Edge, S; El-Sabawi, D; Price, R; Young, PM1
Crowder, T; Hickey, A1
MacRitchie, HB; Marriott, C; Martin, GP; Zeng, XM2
Carter, P; Elajnaf, A; Rowley, G2
Adi, H; Chiou, H; Larson, I; Stewart, P; Traini, D; Young, P2
Marriott, C; Martin, GP; Zeng, XM1
Burnett, D; Chan, HK; Chiou, H; Tee, T; Thielmann, F; Traini, D; Young, PM1
Hickey, AJ; Kujanpää, J; Telko, MJ1
Adi, H; Larson, I; Stewart, PJ1
Chan, HK; Chiou, H; Kwok, P; Sung, A; Traini, D; Young, PM1
Hickey, AJ; Langridge, J; Mansour, HM; McLean, R; Mulder, T; Papadopoulos, D; Smyth, HD; Telko, MJ; Xu, Z1
Dawson, ML; Ferrie, AR; Harris, H; Hooton, JC; Jones, MD; King, GS; Mathoulin, CA; Nichol, K; Price, R; Shur, J; Smith, TL1
Marriott, C; Martin, GP; Murnane, D1
Das, S; Larson, I; Stewart, P; Young, P2
Acharya, M; Thielmann, F; Traini, D; Young, PM1
Ahmad, FJ; Bhatnagar, A; Jain, GK; Khar, RK; Malhotra, G; Mittal, G1
Handoko, A; Ian, L; Peter, SJ1
Biradar, SV; Dhumal, RS; Paradkar, AR; York, P1
Donovan, R; Elder, D; Freney, E; New, A; Prime, D; Zomer, S1
Adi, H; Chan, HK; Kwok, P; Traini, D; Young, PM1
Boshhiha, AM; Urbanetz, NA1
Barrett, A; Brody, R; Guenette, E; Harding, L; Kraus, D; Magee, G1
Bakri, A; Khalef, N; Pinal, R1
Bur, M; Huwer, H; Lehr, CM; Muys, L1
Huang, WH; Liu, L; Wong, YF; Wu, H; Yang, ZJ; Zhao, ZZ1
Hickey, AJ; Langridge, J; Mansour, HM; McLean, R; Mulder, T; Xu, Z1
Buckton, G; Dennison, M; Jones, MD; Master, H; Santo, JG; Yakub, B1
Chan, HK; Hoe, S; Traini, D; Young, PM1
Chaibva, FA; Khamanga, SM; Walker, RB1
Hira, D; Ishizeki, K; Kito, D; Okada, T; Okamoto, H; Okuda, T1
Kaialy, W; Martin, GP; Mohammad, MA; Murphy, J; Nokhodchi, A; Royall, P; Ticehurst, MD1
Behara, SR; Kippax, P; Larson, I; McIntosh, MP; Morton, DA; Stewart, P1
Marriott, C; Martin, GP; Taki, M; Zeng, XM1
Kaialy, W; Murphy, J; Nokhodchi, A; Ticehurst, MD1
Hoe, S; Traini, D; Young, PM1
Anwar, J; de Matas, M; Leusen, FJ; Shariare, MH; York, P1
Alhalaweh, A; Kaialy, W; Nokhodchi, A; Velaga, SP1
Kaialy, W; Kolosionek, E; Larhrib, H; Martin, GP; Nokhodchi, A; Ticehurst, MD1
Kaialy, W; Nokhodchi, A; Ticehurst, M1
Hira, D; Ichihashi, M; Ishizeki, K; Mizutani, A; Okada, T; Okamoto, H; Okuda, T1
Kaialy, W; Larhrib, H; Martin, GP; Nokhodchi, A1
Behara, SR; Kippax, P; Larson, I; Morton, DA; Stewart, P1
Kaialy, W; Nokhodchi, A2
de Boer, HA; Frijlink, HW; Grasmeijer, F; Hagedoorn, P1
Du, J; Du, P; Smyth, HD1
Hebbink, GA; Ho, L; Howell, R; Larson, I; Leslie, P; Margo, K; Morton, DA; Orlando, L; Parks, J; Sim, S1
Collins, E; Forbes, B; Hammond, RB; Jaffari, S; Martin, GP; Murnane, D; Pencheva, K; Pickering, J; Ramachandran, V; Roberts, KJ; Soufian, M1
Bemelmans, NL; Durham, PG; Hickey, AJ; Ziffels, S1
Faulhammer, E; Khinast, JG; Paudel, A; Wahl, V; Zellnitz, S1
Diez, F; Jones, BE; Kayali, N; Polo, L; Saleem, IY1
Brown, M; Forbes, B; Muddle, J; Murnane, D; Page, C; Parisini, I1
Canfield, N; Pennington, J; Seabrooks, L1
Buckton, G; Jones, MD1
Du, J; Du, P; Smyth, HDC1
Fakner, P; Kamplade, J; Mönckedieck, M; Scherließ, R; Steckel, H; Urbanetz, NA; Walzel, P1
Hauptstein, S; Hertel, M; Kobler, M; Scherließ, R; Schwarz, E; Steckel, H1
Guidi, T; Paudel, A; Pinto, JT; Roblegg, E; Zellnitz, S1
Birk, G; Hertel, N; Scherließ, R1
Guo, C; Li, L; Liu, C; Lu, H; Mao, S; Qin, L; Su, J; Sun, Y; Xiong, W; Yu, D; Zhang, X1
Ferdynand, MS; Nokhodchi, A1
Cui, Z; Liu, Q; Mao, S; Qin, L; Shen, X; Sun, Y; Yu, D; Zhang, X1
Lamešić, D; Paudel, A; Pinto, JT; Planinšek, O; Stranzinger, S; Zellnitz, S1
Guan, J; Li, J; Mao, S; Qin, L; Song, R; Su, J; Sun, Y; Zhang, X1
Alderborn, G; Bramer, T; Frenning, G; Rudén, J; Thalberg, K1
Feng, Y; Li, J; Mao, S; Sun, Y; Yu, D; Zhang, X; Zhao, J1
Gong, QQ; Heng, PWS; Liew, CV; Tay, JYS; Veronica, N; Xu, J; Zhang, YP1
Frenning, G; Sarangi, S; Simonsson, A1

Trials

4 trial(s) available for lactose and albuterol

ArticleYear
Comparative bioavailability and pharmacokinetics of three formulations of albuterol.
    Journal of pharmaceutical sciences, 1985, Volume: 74, Issue:2

    Topics: Administration, Oral; Adult; Albuterol; Biological Availability; Calcium Sulfate; Chemistry, Pharmaceutical; Excipients; Humans; Kinetics; Lactose; Male; Solutions; Tablets; Therapeutic Equivalency

1985
Demonstration by placebo response in asthma by means of exercise testing.
    Journal of psychosomatic research, 1973, Volume: 17, Issue:4

    Topics: Adolescent; Albuterol; Asthma; Atropine; Child; Child, Preschool; Cromolyn Sodium; Female; Humans; Lactose; Male; Physical Exertion; Placebos; Pulmonary Ventilation; Sodium Chloride

1973
Influence of realistic inspiratory flow profiles on fine particle fractions of dry powder aerosol formulations.
    Pharmaceutical research, 2007, Volume: 24, Issue:2

    Topics: Administration, Inhalation; Adrenergic beta-Agonists; Aerosols; Albuterol; Anti-Asthmatic Agents; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Computer Simulation; Drug Carriers; Humans; Lactose; Lasers; Maltose; Models, Anatomic; Nebulizers and Vaporizers; Particle Size; Powders; Sorbitol; Terbutaline

2007
Nano-salbutamol dry powder inhalation: a new approach for treating broncho-constrictive conditions.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2009, Volume: 71, Issue:2

    Topics: Administration, Inhalation; Adult; Albuterol; Biological Availability; Bronchodilator Agents; Drug Delivery Systems; Excipients; Female; Humans; Lactose; Lung; Male; Middle Aged; Nanoparticles; Nebulizers and Vaporizers; Particle Size; Powders; Radiopharmaceuticals; Technetium; Tissue Distribution; Young Adult

2009

Other Studies

113 other study(ies) available for lactose and albuterol

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Rheology of model aerosol suspensions.
    The Journal of pharmacy and pharmacology, 1993, Volume: 45, Issue:7

    Topics: Aerosols; Albuterol; Chlorofluorocarbons, Methane; Chloroform; Lactose; Rheology; Suspensions

1993
Characterization of surfactant effect on aggregates in model aerosol propellent suspensions.
    The Journal of pharmacy and pharmacology, 1996, Volume: 48, Issue:4

    Topics: Adrenergic beta-Agonists; Aerosol Propellants; Albuterol; Excipients; Hexoses; Image Processing, Computer-Assisted; Lactose; Particle Size; Rheology; Surface-Active Agents; Suspensions

1996
The effect of surfactant and solid phase concentration on drug aggregates in model aerosol propellent suspensions.
    The Journal of pharmacy and pharmacology, 1996, Volume: 48, Issue:4

    Topics: Adrenergic beta-Agonists; Aerosol Propellants; Albuterol; Image Processing, Computer-Assisted; Kinetics; Lactose; Nebulizers and Vaporizers; Particle Size; Rheology; Surface Properties; Surface-Active Agents; Suspensions

1996
Dry powder inhalers: the influence of device resistance and powder formulation on drug and lactose deposition in vitro.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 1998, Volume: 7, Issue:1

    Topics: Adrenergic beta-Agonists; Albuterol; Chemistry, Pharmaceutical; Drug Carriers; Lactose; Nebulizers and Vaporizers; Particle Size; Powders

1998
Measurement of electrostatic charge decay in pharmaceutical powders and polymer materials used in dry powder inhaler devices.
    Drug development and industrial pharmacy, 1998, Volume: 24, Issue:11

    Topics: Albuterol; Biopharmaceutics; Chemistry, Pharmaceutical; Excipients; Humans; Lactose; Nebulizers and Vaporizers; Polyvinyl Chloride; Powders; Static Electricity

1998
Effects of particle size and adding sequence of fine lactose on the deposition of salbutamol sulphate from a dry powder formulation.
    International journal of pharmaceutics, 1999, May-25, Volume: 182, Issue:2

    Topics: Albuterol; Bronchodilator Agents; Chemistry, Pharmaceutical; Lactose; Particle Size; Powders

1999
The use of different grades of lactose as a carrier for aerosolised salbutamol sulphate.
    International journal of pharmaceutics, 1999, Nov-25, Volume: 191, Issue:1

    Topics: Adrenergic beta-Agonists; Aerosols; Albuterol; Calorimetry, Differential Scanning; Drug Carriers; Image Processing, Computer-Assisted; Lactose; Lasers; Microscopy, Electron, Scanning; Particle Size; Polymers; Temperature

1999
A study of drug-carrier interactions in dry powder inhaler formulations using the Andersen cascade impactor, X-ray microanalysis and time of flight aerosol beam spectrometry (TOFABS).
    Chemical & pharmaceutical bulletin, 2000, Volume: 48, Issue:2

    Topics: Aerosols; Albuterol; Algorithms; Bronchodilator Agents; Drug Carriers; Electron Probe Microanalysis; Lactose; Microscopy, Electron, Scanning; Particle Size; Powders

2000
Quantification of the surface morphologies of lactose carriers and their effect on the in vitro deposition of salbutamol sulphate.
    Chemical & pharmaceutical bulletin, 2000, Volume: 48, Issue:3

    Topics: Adrenergic beta-Agonists; Albuterol; Algorithms; Drug Carriers; Drug Compounding; Lactose; Microscopy, Electron, Scanning; Microscopy, Scanning Probe; Particle Size; Powders; Surface Properties

2000
The influence of carrier morphology on drug delivery by dry powder inhalers.
    International journal of pharmaceutics, 2000, Apr-25, Volume: 200, Issue:1

    Topics: Administration, Inhalation; Albuterol; Algorithms; Bronchodilator Agents; Chromatography, High Pressure Liquid; Crystallization; Drug Carriers; Lactose; Particle Size; Powders

2000
A human oral-throat cast integrated with a twin-stage impinger for evaluation of dry powder inhalers.
    The Journal of pharmacy and pharmacology, 2000, Volume: 52, Issue:7

    Topics: Administration, Inhalation; Albuterol; Bronchodilator Agents; Calibration; Humans; Lactose; Lubrication; Models, Biological; Nebulizers and Vaporizers; Powders

2000
The use of different sugars as fine and coarse carriers for aerosolised salbutamol sulphate.
    International journal of pharmaceutics, 2000, Nov-04, Volume: 208, Issue:1-2

    Topics: Aerosols; Albuterol; Bronchodilator Agents; Carbohydrates; Chemistry, Pharmaceutical; Drug Carriers; Lactose; Mannitol; Particle Size; Pharmaceutic Aids; Powders; Sorbitol

2000
The effects of carrier size and morphology on the dispersion of salbutamol sulphate after aerosolization at different flow rates.
    The Journal of pharmacy and pharmacology, 2000, Volume: 52, Issue:10

    Topics: Aerosol Propellants; Albuterol; Bronchodilator Agents; Drug Carriers; Lactose; Nebulizers and Vaporizers; Particle Size

2000
The use of lactose recrystallised from carbopol gels as a carrier for aerosolised salbutamol sulphate.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2001, Volume: 51, Issue:1

    Topics: Acrylic Resins; Aerosols; Albuterol; Bronchodilator Agents; Crystallization; Drug Carriers; Gels; Lactose; Nebulizers and Vaporizers; Polyvinyls

2001
Evaluation of stereoselective dissolution of racemic salbutamol matrices prepared with commonly used excipients and 1H-NMR study.
    Drug development and industrial pharmacy, 2001, Volume: 27, Issue:5

    Topics: Adrenergic beta-Agonists; Albumins; Albuterol; Cyclodextrins; Drug Delivery Systems; Excipients; Lactose; Magnetic Resonance Spectroscopy; Methylcellulose; Oxazines; Solubility; Tablets

2001
Evaluation of flow properties of dry powder inhalation of salbutamol sulfate with lactose carrier.
    Chemical & pharmaceutical bulletin, 2001, Volume: 49, Issue:10

    Topics: Aerosols; Albuterol; Algorithms; Bronchodilator Agents; Capsules; Chemical Phenomena; Chemistry, Physical; Drug Carriers; Lactose; Microscopy, Electron, Scanning; Particle Size; Powders

2001
A study of single drug particle adhesion interactions using atomic force microscopy.
    International journal of pharmaceutics, 2002, May-15, Volume: 238, Issue:1-2

    Topics: Adhesiveness; Albuterol; Excipients; Glass; Image Processing, Computer-Assisted; Lactose; Microscopy, Atomic Force; Particle Size; Pharmaceutical Preparations; Polytetrafluoroethylene; Powders; Surface Properties

2002
The influence of relative humidity on particulate interactions in carrier-based dry powder inhaler formulations.
    International journal of pharmaceutics, 2002, Oct-10, Volume: 246, Issue:1-2

    Topics: Administration, Inhalation; Albuterol; Budesonide; Chemistry, Pharmaceutical; Crystallization; Drug Carriers; Humidity; Lactose; Microscopy, Atomic Force; Microscopy, Electron; Nebulizers and Vaporizers; Powders

2002
Application of spectrofluorometry for evaluation of dry powder inhalers in vitro.
    Die Pharmazie, 2003, Volume: 58, Issue:2

    Topics: Aerosols; Albuterol; Chromatography, High Pressure Liquid; Drug Carriers; Excipients; Glass; Lactose; Nebulizers and Vaporizers; Powders; Reproducibility of Results; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet

2003
The influence of carrier and drug morphology on drug delivery from dry powder formulations.
    International journal of pharmaceutics, 2003, May-12, Volume: 257, Issue:1-2

    Topics: Albuterol; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Crystallization; Drug Carriers; Lactose; Particle Size; Powders; Thermogravimetry

2003
Immobilization of fine particles on lactose carrier by precision coating and its effect on the performance of dry powder formulations.
    Journal of pharmaceutical sciences, 2003, Volume: 92, Issue:5

    Topics: Albuterol; Drug Carriers; Drug Compounding; Drug Delivery Systems; Lactose; Microscopy, Electron, Scanning; Microscopy, Scanning Probe; Particle Size; Powders; Surface Properties; Suspensions

2003
Characterisation and deposition studies of engineered lactose crystals with potential for use as a carrier for aerosolised salbutamol sulfate from dry powder inhalers.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2003, Volume: 19, Issue:4

    Topics: Acetone; Administration, Inhalation; Aerosols; Albuterol; Calorimetry, Differential Scanning; Chromatography, High Pressure Liquid; Crystallization; Drug Carriers; Lactose; Microscopy, Electron, Scanning; Powders; X-Ray Diffraction

2003
Effect of surface covering of lactose carrier particles on dry powder inhalation properties of salbutamol sulfate.
    Chemical & pharmaceutical bulletin, 2003, Volume: 51, Issue:12

    Topics: Administration, Inhalation; Albuterol; Drug Carriers; Lactose; Powders; Surface Properties

2003
Effect of surface layering time of lactose carrier particles on dry powder inhalation properties of salbutamol sulfate.
    Chemical & pharmaceutical bulletin, 2004, Volume: 52, Issue:3

    Topics: Administration, Inhalation; Albuterol; Drug Carriers; Lactose; Microscopy, Electron, Scanning; Powders; Surface Properties

2004
Effect of carrier size on the dispersion of salmeterol xinafoate from interactive mixtures.
    Journal of pharmaceutical sciences, 2004, Volume: 93, Issue:4

    Topics: Administration, Inhalation; Albuterol; Bronchodilator Agents; Capsules; Chromatography, High Pressure Liquid; Drug Carriers; Lactose; Models, Chemical; Particle Size; Regression Analysis; Salmeterol Xinafoate; Spectrophotometry, Ultraviolet

2004
Contamination of dry powder inhalers for asthma with milk proteins containing lactose.
    The Journal of allergy and clinical immunology, 2004, Volume: 113, Issue:3

    Topics: Administration, Inhalation; Albuterol; Anaphylaxis; Androstadienes; Asthma; Bronchodilator Agents; Child; Drug Combinations; Drug Contamination; Fluticasone-Salmeterol Drug Combination; Humans; Lactose; Male; Milk Hypersensitivity; Milk Proteins; Powders

2004
Predicting the physical state of spray dried composites: salbutamol sulphate/lactose and salbutamol sulphate/polyethylene glycol co-spray dried systems.
    International journal of pharmaceutics, 2004, Apr-01, Volume: 273, Issue:1-2

    Topics: Albuterol; Drug Compounding; Excipients; Lactose; Phase Transition; Polyethylene Glycols; Powders; Predictive Value of Tests; Transition Temperature

2004
Influence of storage humidity on the in vitro inhalation properties of salbutamol sulfate dry powder with surface covered lactose carrier.
    Chemical & pharmaceutical bulletin, 2004, Volume: 52, Issue:4

    Topics: Administration, Inhalation; Albuterol; Bronchodilator Agents; Chemistry, Pharmaceutical; Drug Carriers; Drug Storage; Humidity; Lactose; Magnesium; Microscopy, Electron, Scanning; Powders; Surface Properties

2004
Lactose surface modification by decantation: are drug-fine lactose ratios the key to better dispersion of salmeterol xinafoate from lactose-interactive mixtures?
    Pharmaceutical research, 2004, Volume: 21, Issue:3

    Topics: Administration, Inhalation; Albuterol; Drug Carriers; Lactose; Particle Size; Salmeterol Xinafoate

2004
Use of an impinging jet for dispersion of dry powder inhalation aerosols.
    International journal of pharmaceutics, 2004, May-04, Volume: 275, Issue:1-2

    Topics: Administration, Inhalation; Aerosols; Albuterol; Chemical Phenomena; Chemistry, Physical; Drug Delivery Systems; Lactose; Nebulizers and Vaporizers; Particle Size; Powders

2004
Evaluation of SCF-engineered particle-based lactose blends in passive dry powder inhalers.
    International journal of pharmaceutics, 2004, Aug-20, Volume: 281, Issue:1-2

    Topics: Administration, Inhalation; Albuterol; Budesonide; Chemistry, Pharmaceutical; Chromatography, Supercritical Fluid; Drug Carriers; Drug Delivery Systems; Drug Evaluation, Preclinical; Forecasting; Lactose; Metered Dose Inhalers; Microscopy, Electron, Scanning; Nebulizers and Vaporizers; Particle Size; Powders; United Kingdom

2004
Effects of surface processing of lactose carrier particles on dry powder inhalation properties of salbutamol sulfate.
    Chemical & pharmaceutical bulletin, 2004, Volume: 52, Issue:8

    Topics: Administration, Inhalation; Albuterol; Bronchodilator Agents; Drug Carriers; Lactose; Microscopy, Electron, Scanning; Particle Size; Powders; Surface Properties; Temperature; X-Ray Diffraction

2004
The cohesive-adhesive balances in dry powder inhaler formulations I: Direct quantification by atomic force microscopy.
    Pharmaceutical research, 2004, Volume: 21, Issue:9

    Topics: Adhesiveness; Albuterol; Budesonide; Chemistry, Pharmaceutical; Crystallization; Drug Carriers; Lactose; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Powders

2004
Determining the critical relative humidity for moisture-induced phase transitions.
    International journal of pharmaceutics, 2004, Dec-09, Volume: 287, Issue:1-2

    Topics: Albuterol; Calorimetry, Differential Scanning; Crystallization; Humidity; Lactose; Phase Transition; Volatilization

2004
The cohesive-adhesive balances in dry powder inhaler formulations II: influence on fine particle delivery characteristics.
    Pharmaceutical research, 2004, Volume: 21, Issue:10

    Topics: Adhesiveness; Administration, Inhalation; Aerosols; Albuterol; Bronchodilator Agents; Budesonide; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Excipients; Lactose; Microscopy, Electron, Scanning; Nebulizers and Vaporizers; Particle Size; Powders; Spectrophotometry, Ultraviolet

2004
Preparation of dry powder inhalation with lactose carrier particles surface-coated using a Wurster fluidized bed.
    Chemical & pharmaceutical bulletin, 2005, Volume: 53, Issue:4

    Topics: Administration, Inhalation; Albuterol; Chemical Phenomena; Chemistry, Physical; Drug Carriers; Drug Compounding; Lactose; Microscopy, Electron, Scanning; Particle Size; Powders; Solubility; Surface Properties

2005
Surface roughness contribution to the adhesion force distribution of salmeterol xinafoate on lactose carriers by atomic force microscopy.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Adhesiveness; Adrenergic beta-Agonists; Albuterol; Drug Carriers; Lactose; Microscopy, Atomic Force; Microscopy, Confocal; Salmeterol Xinafoate; Silicon Dioxide; Spectrometry, X-Ray Emission; Surface Properties

2005
Predicting the aerosol performance of dry powder inhalation formulations by interparticulate interaction analysis using inverse gas chromatography.
    Journal of pharmaceutical sciences, 2006, Volume: 95, Issue:1

    Topics: Administration, Inhalation; Adsorption; Aerosols; Albuterol; Bronchodilator Agents; Chemistry, Pharmaceutical; Chromatography, Gas; Forecasting; Humidity; Lactose; Powders; Salmeterol Xinafoate; Solubility

2006
Comparative study of erythritol and lactose monohydrate as carriers for inhalation: atomic force microscopy and in vitro correlation.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2006, Volume: 27, Issue:2-3

    Topics: Administration, Inhalation; Aerosols; Albuterol; Bronchodilator Agents; Crystallization; Drug Carriers; Erythritol; Lactose; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Nebulizers and Vaporizers; Particle Size; Solubility; Volatilization; X-Ray Diffraction

2006
Effect of milling and sieving on functionality of dry powder inhalation products.
    International journal of pharmaceutics, 2006, Feb-17, Volume: 309, Issue:1-2

    Topics: Aerosols; Albuterol; Anti-Inflammatory Agents; Beclomethasone; Bronchodilator Agents; Chemistry, Pharmaceutical; Excipients; Lactose; Microscopy, Electron, Scanning; Models, Biological; Nebulizers and Vaporizers; Particle Size; Powders; Surface Properties; Technology, Pharmaceutical

2006
Air classifier technology (ACT) in dry powder inhalation Part 4. Performance of air classifier technology in the Novolizer multi-dose dry powder inhaler.
    International journal of pharmaceutics, 2006, Mar-09, Volume: 310, Issue:1-2

    Topics: Adhesiveness; Administration, Inhalation; Aerosols; Albuterol; Bronchodilator Agents; Budesonide; Chemistry, Pharmaceutical; Drug Carriers; Equipment Design; Lactose; Nebulizers and Vaporizers; Particle Size; Powders; Surface Properties; Time Factors

2006
Novel temperature controlled surface dissolution of excipient particles for carrier based dry powder inhaler formulations.
    Drug development and industrial pharmacy, 2006, Volume: 32, Issue:2

    Topics: Adrenergic beta-Agonists; Aerosols; Albuterol; Chemistry, Pharmaceutical; Drug Carriers; Excipients; Heating; Lactose; Microscopy, Electron, Scanning; Nebulizers and Vaporizers; Particle Size; Powders; Solubility; Surface Properties; X-Ray Diffraction

2006
Physicochemical and in vitro deposition properties of salbutamol sulphate/ipratropium bromide and salbutamol sulphate/excipient spray dried mixtures for use in dry powder inhalers.
    International journal of pharmaceutics, 2006, Sep-28, Volume: 322, Issue:1-2

    Topics: Aerosols; Albuterol; Calorimetry, Differential Scanning; Drug Compounding; Excipients; Ipratropium; Lactose; Microscopy, Electron, Scanning; Nebulizers and Vaporizers; Particle Size; Polyethylene Glycols; Powders; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction

2006
Powder specific active dispersion for generation of pharmaceutical aerosols.
    International journal of pharmaceutics, 2006, Dec-11, Volume: 327, Issue:1-2

    Topics: Aerosols; Albuterol; Bronchodilator Agents; Excipients; Lactose; Nebulizers and Vaporizers; Polysaccharides; Powders

2006
Development of a laser diffraction method for the determination of the particle size of aerosolised powder formulations.
    International journal of pharmaceutics, 2006, Dec-01, Volume: 326, Issue:1-2

    Topics: Aerosols; Albuterol; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Crystallization; Glass; Glucose; Lactose; Lasers; Maltose; Microscopy, Electron, Scanning; Particle Size; Powders; Scattering, Radiation; Sorbitol

2006
Electrostatic characterisation of inhaled powders: effect of contact surface and relative humidity.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2006, Volume: 29, Issue:5

    Topics: Administration, Inhalation; Albuterol; Bronchodilator Agents; Humidity; Ipratropium; Lactose; Powders; Static Electricity; Surface Properties

2006
Agglomerate strength and dispersion of salmeterol xinafoate from powder mixtures for inhalation.
    Pharmaceutical research, 2006, Volume: 23, Issue:11

    Topics: Administration, Inhalation; Aerosols; Albuterol; Drug Carriers; Lactose; Microscopy, Electron, Scanning; Particle Size; Powders; Salmeterol Xinafoate

2006
Humidity-induced changes of the aerodynamic properties of dry powder aerosol formulations containing different carriers.
    International journal of pharmaceutics, 2007, Mar-21, Volume: 333, Issue:1-2

    Topics: Administration, Inhalation; Aerosols; Albuterol; Bronchodilator Agents; Chemistry, Pharmaceutical; Desiccation; Drug Carriers; Drug Stability; Drug Storage; Excipients; Glucose; Humidity; Lactose; Lasers; Maltose; Microscopy, Electron, Scanning; Nebulizers and Vaporizers; Particle Size; Porosity; Powder Diffraction; Powders; Sorbitol; Surface Properties; Technology, Pharmaceutical; Time Factors; Water

2007
The use of organic vapor sorption to determine low levels of amorphous content in processed pharmaceutical powders.
    Drug development and industrial pharmacy, 2007, Volume: 33, Issue:1

    Topics: Albuterol; Chemistry, Pharmaceutical; Lactose; Powders; Technology, Pharmaceutical; Volatilization

2007
Investigation of triboelectric charging in dry powder inhalers using electrical low pressure impactor (ELPI).
    International journal of pharmaceutics, 2007, May-24, Volume: 336, Issue:2

    Topics: Adrenergic beta-Agonists; Aerosols; Albuterol; Chemistry, Pharmaceutical; Drug Delivery Systems; Excipients; Lactose; Models, Statistical; Nebulizers and Vaporizers; Particle Size; Powders; Reproducibility of Results; Static Electricity

2007
Adhesion and redistribution of salmeterol xinafoate particles in sugar-based mixtures for inhalation.
    International journal of pharmaceutics, 2007, Jun-07, Volume: 337, Issue:1-2

    Topics: Administration, Inhalation; Albuterol; Carbohydrates; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Crystallography, X-Ray; Desiccation; Drug Carriers; Drug Compounding; Excipients; Glucose; Lactose; Lasers; Mannitol; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Particle Size; Reproducibility of Results; Salmeterol Xinafoate; Sorbitol; Surface Properties; Technology, Pharmaceutical; Water

2007
Influence of humidity on the electrostatic charge and aerosol performance of dry powder inhaler carrier based systems.
    Pharmaceutical research, 2007, Volume: 24, Issue:5

    Topics: Aerosols; Albuterol; Bronchodilator Agents; Crystallization; Drug Compounding; Drug Storage; Equipment Design; Humidity; Lactose; Metered Dose Inhalers; Nebulizers and Vaporizers; Particle Size; Powders; Reproducibility of Results; Static Electricity; Technology, Pharmaceutical; Temperature; Volatilization

2007
Physical characterization of component particles included in dry powder inhalers. II. Dynamic characteristics.
    Journal of pharmaceutical sciences, 2007, Volume: 96, Issue:5

    Topics: Administration, Inhalation; Aerosols; Albuterol; Bronchodilator Agents; Chemistry, Pharmaceutical; Crystallization; Drug Carriers; Lactose; Nebulizers and Vaporizers; Powders; Static Electricity; Technology, Pharmaceutical

2007
The effect of relative humidity on electrostatic charge decay of drugs and excipient used in dry powder inhaler formulation.
    Drug development and industrial pharmacy, 2007, Volume: 33, Issue:9

    Topics: Aerosols; Albuterol; Bronchodilator Agents; Chemistry, Pharmaceutical; Excipients; Humidity; Ipratropium; Lactose; Metered Dose Inhalers; Powders; Static Electricity; Technology, Pharmaceutical

2007
Role of agglomeration in the dispersion of salmeterol xinafoate from mixtures for inhalation with differing drug to fine lactose ratios.
    Journal of pharmaceutical sciences, 2008, Volume: 97, Issue:8

    Topics: Administration, Inhalation; Aerosols; Albuterol; Bronchodilator Agents; Chromatography, High Pressure Liquid; Drug Carriers; Lactose; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Particle Size; Salmeterol Xinafoate

2008
An investigation into the relationship between carrier-based dry powder inhalation performance and formulation cohesive-adhesive force balances.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2008, Volume: 69, Issue:2

    Topics: Adhesiveness; Administration, Inhalation; Albuterol; Androstadienes; Anti-Allergic Agents; Capsules; Chemistry, Pharmaceutical; Crystallization; Drug Carriers; Excipients; Fluticasone; Lactose; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Particle Size; Powders; Salmeterol Xinafoate; X-Ray Diffraction

2008
Dry powder formulations for inhalation of fluticasone propionate and salmeterol xinafoate microcrystals.
    Journal of pharmaceutical sciences, 2009, Volume: 98, Issue:2

    Topics: Administration, Inhalation; Adrenergic beta-Agonists; Aerosols; Albuterol; Androstadienes; Bronchodilator Agents; Chemistry, Pharmaceutical; Crystallization; Drug Compounding; Fluticasone; Lactose; Nebulizers and Vaporizers; Particle Size; Polyethylene Glycols; Powders; Salmeterol Xinafoate

2009
Influence of storage relative humidity on the dispersion of salmeterol xinafoate powders for inhalation.
    Journal of pharmaceutical sciences, 2009, Volume: 98, Issue:3

    Topics: Administration, Inhalation; Albuterol; Drug Carriers; Drug Stability; Drug Storage; Excipients; Humans; Humidity; Lactose; Particle Size; Powders; Salmeterol Xinafoate; Thermogravimetry

2009
The influence of lactose pseudopolymorphic form on salbutamol sulfate-lactose interactions in DPI formulations.
    Drug development and industrial pharmacy, 2008, Volume: 34, Issue:9

    Topics: Aerosols; Albuterol; Chemistry, Pharmaceutical; Chromatography, Gas; Lactose; Microscopy; Nebulizers and Vaporizers; Particle Size; X-Ray Diffraction

2008
Influence of the polydispersity of the added fine lactose on the dispersion of salmeterol xinafoate from mixtures for inhalation.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2009, Feb-15, Volume: 36, Issue:2-3

    Topics: Administration, Inhalation; Albuterol; Chemistry, Pharmaceutical; Excipients; Lactose; Microscopy, Electron, Scanning; Nebulizers and Vaporizers; Particle Size; Pharmaceutical Vehicles; Powders; Salmeterol Xinafoate; Sonication

2009
Particle engineering using sonocrystallization: salbutamol sulphate for pulmonary delivery.
    International journal of pharmaceutics, 2009, Feb-23, Volume: 368, Issue:1-2

    Topics: Administration, Inhalation; Albuterol; Bronchodilator Agents; Chemistry, Pharmaceutical; Crystallization; Drug Carriers; Drug Compounding; Drug Delivery Systems; Drug Stability; Lactose; Lung; Nebulizers and Vaporizers; Particle Size; Pharmaceutic Aids; Powders; Sonication

2009
Detection and assessment of co-association in inhalable drug particles using aerosol time-of-flight mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 2008, Volume: 22, Issue:23

    Topics: Administration, Inhalation; Aerosols; Albuterol; Androstadienes; Bronchodilator Agents; Drug Combinations; Fluticasone; Fluticasone-Salmeterol Drug Combination; Humans; Lactose; Mass Spectrometry; Metered Dose Inhalers; Multivariate Analysis; Nebulizers and Vaporizers; Particle Size; Principal Component Analysis; Salmeterol Xinafoate

2008
Lactose composite carriers for respiratory delivery.
    Pharmaceutical research, 2009, Volume: 26, Issue:4

    Topics: Adhesiveness; Administration, Inhalation; Aerosols; Albuterol; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Crystallization; Crystallography, X-Ray; Drug Carriers; Drug Compounding; Lactose; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Nebulizers and Vaporizers; Particle Size; Powder Diffraction; Powders; Respiratory System Agents; Surface Properties; Technology, Pharmaceutical

2009
Influence of carrier surface fines on dry powder inhalation formulations.
    Drug development and industrial pharmacy, 2009, Volume: 35, Issue:8

    Topics: Administration, Inhalation; Albuterol; Drug Carriers; Lactose; Mannitol; Particle Size; Powders; Surface Properties

2009
Agglomerate properties and dispersibility changes of salmeterol xinafoate from powders for inhalation after storage at high relative humidity.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2009, Jun-28, Volume: 37, Issue:3-4

    Topics: Administration, Inhalation; Aerosols; Albuterol; Bronchodilator Agents; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Compounding; Drug Stability; Drug Storage; Excipients; Humidity; Lactose; Microscopy, Electron, Scanning; Particle Size; Powders; Pressure; Salmeterol Xinafoate

2009
Understanding the effect of lactose particle size on the properties of DPI formulations using experimental design.
    International journal of pharmaceutics, 2009, Oct-01, Volume: 380, Issue:1-2

    Topics: Administration, Inhalation; Albuterol; Dosage Forms; Drug Carriers; Drug Compounding; Drug Stability; Lactose; Microscopy, Electron, Scanning; Particle Size; Powders; Rheology

2009
Limitations of amorphous content quantification by isothermal calorimetry using saturated salt solutions to control relative humidity: alternative methods.
    Journal of pharmaceutical sciences, 2010, Volume: 99, Issue:4

    Topics: Albuterol; Calorimetry; Crystallization; Humidity; Lactose; Salts; Solutions; Thermodynamics; Water

2010
Drug transport across pulmonary epithelial cell monolayers: effects of particle size, apical liquid volume, and deposition technique.
    Journal of aerosol medicine and pulmonary drug delivery, 2010, Volume: 23, Issue:3

    Topics: Administration, Inhalation; Aerosols; Albuterol; Biological Transport; Bronchi; Bronchodilator Agents; Budesonide; Cell Line; Crystallization; Drug Delivery Systems; Drugs, Generic; Epithelial Cells; Excipients; Humans; Lactose; Nebulizers and Vaporizers; Particle Size; Solubility; Therapeutic Equivalency

2010
Development of liposomal salbutamol sulfate dry powder inhaler formulation.
    Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:3

    Topics: Administration, Inhalation; Albuterol; Bronchodilator Agents; Chemistry, Pharmaceutical; Lactose; Liposomes; Lubrication; Nebulizers and Vaporizers; Particle Size; Phospholipids; Powders; Stearic Acids

2010
Dry powder aerosols generated by standardized entrainment tubes from drug blends with lactose monohydrate: 1. Albuterol sulfate and disodium cromoglycate.
    Journal of pharmaceutical sciences, 2010, Volume: 99, Issue:8

    Topics: Adsorption; Aerosols; Albuterol; Anti-Asthmatic Agents; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Cromolyn Sodium; Crystallization; Drug Carriers; Drug Compounding; Lactose; Lasers; Microscopy, Electron, Scanning; Particle Size; Powders; Thermodynamics; X-Ray Diffraction

2010
The relationship between drug concentration, mixing time, blending order and ternary dry powder inhalation performance.
    International journal of pharmaceutics, 2010, May-31, Volume: 391, Issue:1-2

    Topics: Administration, Inhalation; Albuterol; Chemistry, Pharmaceutical; Drug Carriers; Lactose; Particle Size; Powders; Rheology; Surface Properties; Time Factors

2010
The contribution of different formulation components on the aerosol charge in carrier-based dry powder inhaler systems.
    Pharmaceutical research, 2010, Volume: 27, Issue:7

    Topics: Administration, Inhalation; Albuterol; Bronchodilator Agents; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Carriers; Lactose; Microscopy, Electron, Scanning; Nebulizers and Vaporizers; Particle Size; Powders; Static Electricity

2010
Swelling, erosion and drug release characteristics of salbutamol sulfate from hydroxypropyl methylcellulose-based matrix tablets.
    Drug development and industrial pharmacy, 2010, Volume: 36, Issue:12

    Topics: Acrylates; Albuterol; Carboxymethylcellulose Sodium; Chemistry, Pharmaceutical; Hardness; Kinetics; Lactose; Methylcellulose; Microscopy, Electron, Scanning; Solubility; Tablets

2010
Inhalation performance of physically mixed dry powders evaluated with a simple simulator for human inspiratory flow patterns.
    Pharmaceutical research, 2010, Volume: 27, Issue:10

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Albuterol; Chromatography, High Pressure Liquid; Dry Powder Inhalers; Humans; Lactose; Microscopy, Electron, Scanning; Models, Biological; Powders; Surface Properties

2010
Characterisation and deposition studies of recrystallised lactose from binary mixtures of ethanol/butanol for improved drug delivery from dry powder inhalers.
    The AAPS journal, 2011, Volume: 13, Issue:1

    Topics: Aerosols; Albuterol; Bronchodilator Agents; Butanols; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Crystallization; Drug Delivery Systems; Dry Powder Inhalers; Ethanol; Excipients; Image Processing, Computer-Assisted; Lactose; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Particle Size; Powders; Spectroscopy, Fourier Transform Infrared

2011
Structural influence of cohesive mixtures of salbutamol sulphate and lactose on aerosolisation and de-agglomeration behaviour under dynamic conditions.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2011, Feb-14, Volume: 42, Issue:3

    Topics: Aerosols; Albuterol; Chromatography, High Pressure Liquid; Lactose; Microscopy, Electron, Scanning; Molecular Structure; Particle Size

2011
The production of 'aerodynamically equivalent' drug and excipient inhalable powders using a novel fractionation technique.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2011, Volume: 77, Issue:2

    Topics: Administration, Inhalation; Aerosols; Albuterol; Androstadienes; Anti-Allergic Agents; Bronchodilator Agents; Chemical Fractionation; Crystallization; Drug Compounding; Excipients; Fluticasone; Humans; Lactose; Nebulizers and Vaporizers; Particle Size; Powders; Salmeterol Xinafoate

2011
Improved aerosolization performance of salbutamol sulfate formulated with lactose crystallized from binary mixtures of ethanol-acetone.
    Journal of pharmaceutical sciences, 2011, Volume: 100, Issue:7

    Topics: Acetone; Adhesiveness; Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Aerosols; Albuterol; Bronchodilator Agents; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Crystallization; Drug Carriers; Drug Compounding; Dry Powder Inhalers; Ethanol; Lactose; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Particle Size; Powders; Rheology; Solvents; Spectroscopy, Fourier Transform Infrared; Surface Properties; Technology, Pharmaceutical

2011
Dynamic electrostatic charge of lactose-salbutamol sulphate powder blends dispersed from a Cyclohaler®.
    Drug development and industrial pharmacy, 2011, Volume: 37, Issue:11

    Topics: Administration, Inhalation; Albuterol; Bronchodilator Agents; Drug Carriers; Lactose; Microscopy, Electron, Scanning; Nebulizers and Vaporizers; Particle Size; Powders; Static Electricity

2011
Prediction of the mechanical behaviour of crystalline solids.
    Pharmaceutical research, 2012, Volume: 29, Issue:1

    Topics: Acetaminophen; Albuterol; Anisotropy; Chromatography, Gas; Crystallization; Ibuprofen; Lactose; Particle Size; Powders; Stress, Mechanical; Surface Properties; Thermodynamics

2012
Effect of carrier particle shape on dry powder inhaler performance.
    International journal of pharmaceutics, 2011, Dec-12, Volume: 421, Issue:1

    Topics: Albuterol; Bronchodilator Agents; Drug Carriers; Dry Powder Inhalers; Lactose; Mannitol; Particle Size; Porosity; Rheology

2011
The influence of physical properties and morphology of crystallised lactose on delivery of salbutamol sulphate from dry powder inhalers.
    Colloids and surfaces. B, Biointerfaces, 2012, Jan-01, Volume: 89

    Topics: Albuterol; Bronchodilator Agents; Crystallization; Lactose; Microscopy, Electron, Scanning; Nebulizers and Vaporizers; Particle Size; Powders; Surface Properties

2012
Dry powder inhalers: mechanistic evaluation of lactose formulations containing salbutamol sulphate.
    International journal of pharmaceutics, 2012, Feb-28, Volume: 423, Issue:2

    Topics: Adhesiveness; Administration, Inhalation; Aerosols; Albuterol; Chemistry, Pharmaceutical; Drug Carriers; Drug Compounding; Dry Powder Inhalers; Lactose; Linear Models; Microscopy, Electron, Scanning; Particle Size; Powders; Rheology; Surface Properties; Technology, Pharmaceutical

2012
Influence of peak inspiratory flow rates and pressure drops on inhalation performance of dry powder inhalers.
    Chemical & pharmaceutical bulletin, 2012, Volume: 60, Issue:3

    Topics: Administration, Inhalation; Adult; Albuterol; Bronchodilator Agents; Chemistry, Pharmaceutical; Dry Powder Inhalers; Female; Humans; Inhalation; Lactose; Male; Particle Size; Powders; Pressure; Young Adult

2012
The effect of engineered mannitol-lactose mixture on dry powder inhaler performance.
    Pharmaceutical research, 2012, Volume: 29, Issue:8

    Topics: Administration, Inhalation; Albuterol; Bronchodilator Agents; Calorimetry, Differential Scanning; Crystallization; Drug Carriers; Dry Powder Inhalers; Humans; Lactose; Mannitol; Particle Size; Powder Diffraction; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction

2012
Insight into pressure drop dependent efficiencies of dry powder inhalers.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2012, Jun-14, Volume: 46, Issue:3

    Topics: Aerosols; Albuterol; Capsules; Chemistry, Pharmaceutical; Dry Powder Inhalers; Efficiency; Lactose; Particle Size; Powders; Pressure

2012
Antisolvent crystallisation is a potential technique to prepare engineered lactose with promising aerosolisation properties: effect of saturation degree.
    International journal of pharmaceutics, 2012, Nov-01, Volume: 437, Issue:1-2

    Topics: 1-Butanol; Aerosols; Albuterol; Bronchodilator Agents; Crystallization; Drug Compounding; Dry Powder Inhalers; Ethanol; Lactose; Particle Size; Solvents

2012
Engineered mannitol ternary additives improve dispersion of lactose-salbutamol sulphate dry powder inhalations.
    The AAPS journal, 2013, Volume: 15, Issue:3

    Topics: Albuterol; Chemical Engineering; Chemistry, Pharmaceutical; Dry Powder Inhalers; Lactose; Mannitol; Particle Size; Sulfates; X-Ray Diffraction

2013
Mixing time effects on the dispersion performance of adhesive mixtures for inhalation.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: Administration, Inhalation; Albuterol; Androstadienes; Chemistry, Pharmaceutical; Drug Carriers; Fluticasone; Lactose; Lasers; Microscopy, Electron, Scanning; Particle Size; Salmeterol Xinafoate; Solubility; Time Factors; X-Ray Diffraction

2013
Evaluation of granulated lactose as a carrier for DPI formulations 1: effect of granule size.
    AAPS PharmSciTech, 2014, Volume: 15, Issue:6

    Topics: Adhesiveness; Administration, Inhalation; Aerosols; Albuterol; Capsules; Drug Carriers; Dry Powder Inhalers; Lactose; Particle Size; Powders; Rheology; Surface Properties; Technology, Pharmaceutical; Temperature

2014
An insight into powder entrainment and drug delivery mechanisms from a modified Rotahaler®.
    International journal of pharmaceutics, 2014, Dec-30, Volume: 477, Issue:1-2

    Topics: Aerosols; Albuterol; Bronchodilator Agents; Drug Carriers; Drug Delivery Systems; Dry Powder Inhalers; Lactose; Microscopy, Electron, Scanning; Models, Theoretical; Particle Size; Powders; Surface Properties

2014
Formulation pre-screening of inhalation powders using computational atom-atom systematic search method.
    Molecular pharmaceutics, 2015, Jan-05, Volume: 12, Issue:1

    Topics: Administration, Inhalation; Aerosols; Albuterol; Androstadienes; Budesonide; Chemistry, Pharmaceutical; Chromatography, Gas; Computer Simulation; Crystallization; Drug Delivery Systems; Excipients; Fluticasone; Hydrogen Bonding; Lactose; Lasers; Models, Theoretical; Particle Size; Powders; Static Electricity; Surface Properties

2015
In vitro dry powder inhaler formulation performance considerations.
    Journal of controlled release : official journal of the Controlled Release Society, 2015, Feb-10, Volume: 199

    Topics: Albuterol; Anti-Asthmatic Agents; Budesonide; Chemistry, Pharmaceutical; Drug Carriers; Drug Delivery Systems; Dry Powder Inhalers; Excipients; In Vitro Techniques; Lactose; Particle Size; Powders

2015
Carrier-based dry powder inhalation: Impact of carrier modification on capsule filling processability and in vitro aerodynamic performance.
    International journal of pharmaceutics, 2015, Aug-01, Volume: 491, Issue:1-2

    Topics: Administration, Inhalation; Albuterol; Bronchodilator Agents; Capsules; Desiccation; Drug Carriers; Drug Compounding; Dry Powder Inhalers; Lactose; Mannitol; Particle Size; Porosity; Powders

2015
Investigation on the aerosol performance of dry powder inhalation hypromellose capsules with different lubricant levels.
    International journal of pharmaceutics, 2015, Aug-15, Volume: 492, Issue:1-2

    Topics: Aerosols; Albuterol; Capsules; Dry Powder Inhalers; Hypromellose Derivatives; Lactose; Lubricants; Oleic Acids

2015
Interaction of Formulation and Device Factors Determine the In Vitro Performance of Salbutamol Sulphate Dry Powders for Inhalation.
    Journal of pharmaceutical sciences, 2015, Volume: 104, Issue:11

    Topics: Administration, Inhalation; Albuterol; Bronchodilator Agents; Dry Powder Inhalers; Excipients; Lactose; Particle Size; Sulfates

2015
Development of a directly correlated Raman and uHPLC-MS content uniformity method for dry powder inhalers through statistical design, chemometrics and mathematical modeling.
    Drug development and industrial pharmacy, 2016, Volume: 42, Issue:9

    Topics: Albuterol; Algorithms; Caffeine; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Dry Powder Inhalers; Lactose; Mass Spectrometry; Models, Theoretical; Powders; Spectrum Analysis, Raman

2016
Comparison of the cohesion-adhesion balance approach to colloidal probe atomic force microscopy and the measurement of Hansen partial solubility parameters by inverse gas chromatography for the prediction of dry powder inhalation performance.
    International journal of pharmaceutics, 2016, Jul-25, Volume: 509, Issue:1-2

    Topics: Adhesiveness; Administration, Inhalation; Albuterol; Beclomethasone; Budesonide; Chemistry, Pharmaceutical; Chromatography, Gas; Colloids; Drug Carriers; Dry Powder Inhalers; Erythritol; Lactose; Mannitol; Microscopy, Atomic Force; Particle Size; Pharmaceutical Preparations; Powders; Solubility; Terbutaline; Triamcinolone Acetonide

2016
Evaluation of Granulated Lactose as a Carrier for Dry Powder Inhaler Formulations 2: Effect of Drugs and Drug Loading.
    Journal of pharmaceutical sciences, 2017, Volume: 106, Issue:1

    Topics: Administration, Inhalation; Aerosols; Albuterol; Antibiotics, Antitubercular; Bronchodilator Agents; Drug Carriers; Drug Compounding; Dry Powder Inhalers; Lactose; Particle Size; Rifampin; Surface Properties

2017
Dry powder inhaler performance of spray dried mannitol with tailored surface morphologies as carrier and salbutamol sulphate.
    International journal of pharmaceutics, 2017, May-30, Volume: 524, Issue:1-2

    Topics: Administration, Inhalation; Aerosols; Albuterol; Drug Carriers; Dry Powder Inhalers; Lactose; Mannitol; Particle Size; Powders

2017
Powder flow analysis: A simple method to indicate the ideal amount of lactose fines in dry powder inhaler formulations.
    International journal of pharmaceutics, 2018, Jan-15, Volume: 535, Issue:1-2

    Topics: Administration, Inhalation; Albuterol; Chemistry, Pharmaceutical; Drug Carriers; Drug Compounding; Drug Delivery Systems; Dry Powder Inhalers; Lactose; Particle Size; Powders; Rheology; Surface Properties

2018
Assessment of Dry Powder Inhaler Carrier Targeted Design: A Comparative Case Study of Diverse Anomeric Compositions and Physical Properties of Lactose.
    Molecular pharmaceutics, 2018, 07-02, Volume: 15, Issue:7

    Topics: Adhesiveness; Administration, Inhalation; Albuterol; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Drug Carriers; Dry Powder Inhalers; Lactose; Particle Size; Polyethylene Glycols; Powders

2018
Particle engineered mannitol for carrier-based inhalation - A serious alternative?
    International journal of pharmaceutics, 2020, Mar-15, Volume: 577

    Topics: Administration, Inhalation; Albuterol; Budesonide; Drug Carriers; Dry Powder Inhalers; Lactose; Mannitol; Mechanical Phenomena; Particle Size

2020
Exploring the influence of drug content on DPI powder properties and potential prediction of pulmonary drug deposition.
    International journal of pharmaceutics, 2020, Feb-15, Volume: 575

    Topics: Administration, Inhalation; Albuterol; Bronchodilator Agents; Chemistry, Pharmaceutical; Dry Powder Inhalers; Lactose; Particle Size; Rheology; Surface Properties

2020
Co-spraying of carriers (mannitol-lactose) as a method to improve aerosolization performance of salbutamol sulfate dry powder inhaler.
    Drug delivery and translational research, 2020, Volume: 10, Issue:5

    Topics: Albuterol; Dry Powder Inhalers; Lactose; Mannitol; Particle Size; Sulfates; Technology, Pharmaceutical

2020
Exploring the potential influence of drug charge on downstream deposition behaviour of DPI powders.
    International journal of pharmaceutics, 2020, Oct-15, Volume: 588

    Topics: Administration, Inhalation; Aerosols; Albuterol; Drug Carriers; Dry Powder Inhalers; Lactose; Particle Size; Pharmaceutical Preparations; Powders

2020
Spherical agglomerates of lactose as potential carriers for inhalation.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2021, Volume: 159

    Topics: Administration, Inhalation; Aerosols; Albuterol; Chemistry, Pharmaceutical; Drug Carriers; Dry Powder Inhalers; Lactose; Particle Size; Powders; Surface Properties

2021
Elucidating the Effect of Fine Lactose Ratio on the Rheological Properties and Aerodynamic Behavior of Dry Powder for Inhalation.
    The AAPS journal, 2021, 04-15, Volume: 23, Issue:3

    Topics: Administration, Inhalation; Albuterol; Bronchodilator Agents; Chemistry, Pharmaceutical; Drug Carriers; Drug Compounding; Dry Powder Inhalers; Lactose; Models, Chemical; Particle Size; Powders; Rheology

2021
Effect of pressure drop on the in vitro dispersion of adhesive mixtures of different blend states for inhalation.
    International journal of pharmaceutics, 2022, Apr-05, Volume: 617

    Topics: Adhesives; Administration, Inhalation; Albuterol; Drug Carriers; Dry Powder Inhalers; Lactose; Particle Size; Powders

2022
Elucidation of lactose fine size and drug shape on rheological properties and aerodynamic behavior of dry powders for inhalation.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2022, Volume: 179

    Topics: Administration, Inhalation; Aerosols; Albuterol; Drug Carriers; Dry Powder Inhalers; Lactose; Particle Size; Powders; Sulfates

2022
Surface Modification of lactose carrier particles using a fluid bed coater to improve fine particle fraction for dry powder inhalers.
    Pharmaceutical development and technology, 2023, Volume: 28, Issue:2

    Topics: Administration, Inhalation; Aerosols; Albuterol; Drug Carriers; Drug Delivery Systems; Dry Powder Inhalers; Excipients; Lactose; Particle Size; Powders; Surface Properties

2023
Segregation in inhalable powders: Quantification of the effect of vibration on adhesive mixtures.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2023, Volume: 187

    Topics: Adhesives; Administration, Inhalation; Aerosols; Albuterol; Drug Carriers; Dry Powder Inhalers; Lactose; Particle Size; Powders; Vibration

2023