indazoles and valine
indazoles has been researched along with valine in 51 studies
Research
Studies (51)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (1.96) | 29.6817 |
| 2010's | 37 (72.55) | 24.3611 |
| 2020's | 13 (25.49) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Laute, MA; Manto, M; Pandolfo, M | 1 |
| Goda, Y; Inoue, K; Kikura-Hanajiri, R; Min, JZ; Suzuki, M; Takayama, T; Todoroki, K; Toyo'oka, T | 1 |
| Castaneto, MS; Huestis, MA; Kronstrand, R; Pang, S; Scheidweiler, KB; Wohlfarth, A; Zhu, M | 1 |
| Covaci, A; Erratico, C; Maudens, K; Neels, H; Negreira, N; Norouzizadeh, H; van Nuijs, AL | 1 |
| Gonmori, K; Hasegawa, K; Minakata, K; Nozawa, H; Suzuki, O; Watanabe, K; Wurita, A; Yamagishi, I | 1 |
| Akpunonu, P; Gerona, R; Glauner, K; Hoehn, KS; Thornton, SL | 1 |
| Couper, FJ; Peterson, BL | 1 |
| Bazydlo, L; De Portu, G; Dobrowolski, PJ; Elie, MC; Endres, G; Gerona, R; Hanley, JR; Holder, M; Iovine, N; Lucas, J; Myers, P; Plourde, M; Rand, K; Ryan, MF; Schwartz, M; Slish, J; St Germaine, D; Trecki, J; Tyndall, JA; Weeks, E | 1 |
| Hess, C; Krueger, L; Madea, B; Murach, J; Scharrenbroch, L; Sydow, K; Unger, M | 1 |
| Banister, SD; Connor, M; Glass, M; Kassiou, M; Kevin, R; Longworth, M; Mack, JB; McGregor, IS; Sachdev, S; Santiago, M; Stuart, J | 1 |
| Marusich, JA; Thomas, BF; Wiley, JL | 1 |
| Banka, SS; Hamilton, RJ; Keyfes, V | 1 |
| Asada, A; Doi, T; Kamata, H; Katagi, M; Sawabe, Y; Tagami, T; Takeda, A | 1 |
| Adams, AJ; Banister, SD; Gerona, R; Irizarry, L; Schwartz, M; Trecki, J | 1 |
| Banister, SD; Kassiou, M; Kevin, RC; McGregor, IS; Mitchell, AJ; Moir, M; Stuart, J; Wood, KE | 1 |
| Brown, JM | 1 |
| Curtis, B; Fort, C; Jourdan, T | 1 |
| Cho, HS; In, S; Kim, E; Lee, J; Sim, J | 1 |
| Abouchedid, R; Archer, JRH; Bailey, G; Dargan, PI; Dines, A; Ho, JH; Hudson, S; Sadones, N; Stove, CP; Thurtle, N; Wood, DM; Wood, M; Yamamoto, T | 1 |
| Kawamura, M; Kikura-Hanajiri, R; Maeda, H; Nagashima, E; Yoshida, KI | 1 |
| Maurer, HH; Meyer, MR; Richter, LHJ | 1 |
| Armenian, P; Brandehoff, NP; Clark, S; Darracq, M; Gevorkyan, J; Kaye, B | 1 |
| Angerer, V; Auwärter, V; Eyer, F; Franz, F; Hermanns-Clausen, M; Kithinji, J; Liebetrau, G; Müller, D; Neurath, H | 1 |
| Angerer, V; Auwärter, V; Franz, F; Jacobi, S; Pietsch, J | 1 |
| Gerona, R; Ramsey, JG; Tapp, L; Wen, A | 1 |
| Aylsworth, A; Comas, T; Costain, WJ; Hewitt, M; Marleau, V; Rasquinha, I; Rouleau, Y; Soo, EC; Tauskela, JS | 1 |
| Bader, M; Cohen, E; Gabet, Y; Katz, Y; Lenchinski, T; Meningher, I; Pick, CG; Rotenberg, M; Rubovitch, V; Schreiber, S; Wolf, EU | 1 |
| Farquhar, CE; Gamage, TF; Kevin, RC; Lefever, TW; Marusich, JA; McGregor, IS; Thomas, BF; Wiley, JL | 1 |
| Hasegawa, K; Kitamoto, T; Minakata, K; Nozawa, H; Suzuki, M; Suzuki, O; Watanabe, K; Yamagishi, I | 2 |
| Crane, J; Ewing, L; Fantegrossi, WE; Fujiwara, R; Lockhart, T; Radominska-Pandya, A; Tai, S; Wilson, CD | 1 |
| Ameline, A; Arbouche, N; Garnier, D; Kintz, P; Raul, JS | 1 |
| Atanasov, VN; Burdzhiev, N; Ivanov, ID; Ivanova, E; Pantcheva, I; Stoykova, S; Vlahova, A | 1 |
| Aldridge, R; Bradberry, S; Ford, L | 1 |
| Glass, M; Lefever, TW; Thomas, BF; Wiley, JL | 1 |
| Kula, K; Kłys, M; Rojek, S; Romańczuk, A | 1 |
| Cannaert, A; Fabregat-Safont, D; Hernández, F; Ibáñez, M; Linnet, K; Mardal, M; Noble, C; Sancho, JV; Stove, CP | 1 |
| Banister, SD; Finlay, DB; Glass, M; Ibsen, MS; Javitch, JA; Macdonald, CE; Manning, JJ; Patel, M | 1 |
| Dimmito, MP; Dvorácskó, S; Minosi, P; Mollica, A; Pieretti, S; Stefanucci, A; Tömböly, C; Zengin, G | 1 |
| Chronister, CW; Goldberger, BA; Hvozdovich, JA; Logan, BK | 1 |
| Auwärter, V; Franz, F; Haschimi, B; King, LA | 1 |
| Hassan, VR; Johnson, CS; Kappatos, DC; Kolbe, E; Partington, HK; Somerville, RF; Stansfield, CR | 1 |
| Castaneto, MS; Jansen-Varnum, SA; Logan, BK; Presley, BC | 1 |
| Bishop-Freeman, SC; Krotulski, AJ; Logan, BK; Mohr, ALA | 1 |
| Busquets-Garcia, A; Callado, LF; Fernandez, M; Gomez-Sotres, P; Ioannidou, C; Marsicano, G; Muguruza, C; Oliveira da Cruz, JF; Pagano Zottola, AC | 1 |
| Antonides, LH; Brandon, AM; Epemolu, O; McKenzie, C; McKeown, DA; Read, KD; Riley, J | 1 |
| Barneo-Muñoz, M; Davidsen, AB; Fabregat-Safont, D; Hernández, F; Ibáñez, M; Mardal, M; Martinez-Garcia, F; Mata-Pesquera, M; Sancho, JV | 1 |
| Kula, K; Kłys, M; Maciów-Głąb, M; Moskała, A; Rojek, S; Romańczuk, A; Rzepecka-Woźniak, E; Synowiec, K | 1 |
| Banister, SD; Boyd, R; Chen, S; Connor, M; Finlay, D; Gerona, RR; Glass, M; Hibbs, DE; Kevin, RC; Lai, F; Maloney, CJ; Manning, JJ; Markham, J; McGregor, E; McGregor, IS; Sparkes, E | 1 |
| Fantegrossi, WE; Hiranita, T; Wilson, CD | 1 |
| Fantegrossi, WE; Wilson, CD; Zheng, F | 1 |
Reviews
2 review(s) available for indazoles and valine
| Article | Year |
|---|---|
Combination Chemistry: Structure-Activity Relationships of Novel Psychoactive Cannabinoids.
Topics: Animals; Body Temperature Regulation; Brain; Cannabinoids; Designer Drugs; Dronabinol; Humans; Indazoles; Indoles; Locomotion; Naphthalenes; Nociception; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Structure-Activity Relationship; Valine | 2017 |
Intoxication from the novel synthetic cannabinoids AB-PINACA and ADB-PINACA: A case series and review of the literature.
Topics: Adult; Aggression; Delirium; Designer Drugs; Electroencephalography; Humans; Indazoles; Male; Molecular Structure; Seizures; Tandem Mass Spectrometry; Valine | 2018 |
Other Studies
49 other study(ies) available for indazoles and valine
| Article | Year |
|---|---|
Depression of extra-cellular GABA and increase of NMDA-induced nitric oxide following acute intra-nuclear administration of alcohol in the cerebellar nuclei of the rat.
Topics: Animals; Central Nervous System Depressants; Cerebellar Nuclei; Enzyme Inhibitors; Ethanol; Excitatory Amino Acid Antagonists; Extracellular Fluid; GABA Agonists; gamma-Aminobutyric Acid; Indazoles; Injections, Intraventricular; Male; Microdialysis; N-Methylaspartate; Nipecotic Acids; Nitric Oxide; Quinoxalines; Rats; Rats, Wistar; Tiagabine; Valine | 2005 |
UPLC/ESI-MS/MS-based determination of metabolism of several new illicit drugs, ADB-FUBINACA, AB-FUBINACA, AB-PINACA, QUPIC, 5F-QUPIC and α-PVT, by human liver microsome.
Topics: Chromatography, High Pressure Liquid; Humans; Illicit Drugs; Indazoles; Microsomes, Liver; Molecular Structure; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Valine | 2014 |
Pentylindole/Pentylindazole Synthetic Cannabinoids and Their 5-Fluoro Analogs Produce Different Primary Metabolites: Metabolite Profiling for AB-PINACA and 5F-AB-PINACA.
Topics: Algorithms; Chromatography, Liquid; Computer Simulation; Hepatocytes; Humans; Indazoles; Mass Spectrometry; Microsomes, Liver; Tandem Mass Spectrometry; Time Factors; Valine | 2015 |
In vitro and in vivo human metabolism of the synthetic cannabinoid AB-CHMINACA.
Topics: Cannabinoids; Chromatography, Liquid; Cytochrome P-450 Enzyme System; Designer Drugs; Humans; Hydroxylation; Indazoles; Mass Spectrometry; Microsomes, Liver; Valine | 2015 |
Identification and quantification of metabolites of AB-CHMINACA in a urine specimen of an abuser.
Topics: Autopsy; Chromatography, Liquid; Forensic Toxicology; Humans; Indazoles; Substance Abuse Detection; Tandem Mass Spectrometry; Valine | 2016 |
Unintentional Pediatric Exposure to a Synthetic Cannabinoid (AB-PINACA) Resulting in Coma and Intubation.
Topics: Coma; Emergency Service, Hospital; Female; Humans; Illicit Drugs; Indazoles; Infant; Intubation, Intratracheal; Valine | 2015 |
Concentrations of AB-CHMINACA and AB-PINACA and Driving Behavior in Suspected Impaired Driving Cases.
Topics: Adolescent; Adult; Automobile Driving; Behavior; Female; Humans; Indazoles; Male; Middle Aged; Valine; Young Adult | 2015 |
An outbreak of acute delirium from exposure to the synthetic cannabinoid AB-CHMINACA.
Topics: Acute Disease; Adolescent; Adult; Biotransformation; Cannabinoids; Delirium; Designer Drugs; Disease Outbreaks; Female; Humans; Indazoles; Male; Middle Aged; Molecular Structure; Retrospective Studies; Valine; Young Adult | 2015 |
Simultaneous detection of 93 synthetic cannabinoids by liquid chromatography-tandem mass spectrometry and retrospective application to real forensic samples.
Topics: Cannabinoids; Chromatography, Liquid; Forensic Medicine; Humans; Illicit Drugs; Indazoles; Indoles; Limit of Detection; Male; Retrospective Studies; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Tandem Mass Spectrometry; Valine | 2017 |
Pharmacology of Valinate and tert-Leucinate Synthetic Cannabinoids 5F-AMBICA, 5F-AMB, 5F-ADB, AMB-FUBINACA, MDMB-FUBINACA, MDMB-CHMICA, and Their Analogues.
Topics: Analgesics; Animals; Body Temperature; Cannabinoids; Cyclohexanols; Dose-Response Relationship, Drug; Heart Rate; Humans; Indazoles; Indoles; Leucine; Rats; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Valine | 2016 |
Synthetic Cannabinoid Abuse Resulting in ST-Segment Elevation Myocardial Infarction Requiring Percutaneous Coronary Intervention.
Topics: Chest Pain; Emergency Service, Hospital; Endocannabinoids; Humans; Hypotension; Indazoles; Indoles; Male; Middle Aged; Percutaneous Coronary Intervention; Quinolines; ST Elevation Myocardial Infarction; Substance-Related Disorders; Valine | 2017 |
Enantioseparation of the carboxamide-type synthetic cannabinoids N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide and methyl [1-(5-fluoropentyl)-1H-indazole-3-carbonyl]-valinate in illicit herbal products.
Topics: Cannabinoids; Chromatography, Liquid; Indazoles; Mass Spectrometry; Plant Preparations; Valine | 2016 |
"Zombie" Outbreak Caused by the Synthetic Cannabinoid AMB-FUBINACA in New York.
Topics: Adult; Cannabinoids; Disease Outbreaks; Drug Discovery; Humans; Illicit Drugs; Indazoles; Lethargy; Male; Middle Aged; New York City; Valine | 2017 |
Acute and residual effects in adolescent rats resulting from exposure to the novel synthetic cannabinoids AB-PINACA and AB-FUBINACA.
Topics: Animals; Cannabinoid Receptor Agonists; Cannabinoids; Dronabinol; Endocannabinoids; Illicit Drugs; Indazoles; Locomotion; Male; Memory Disorders; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Valine | 2017 |
Real life zombie apocalypse in New York City.
Topics: Cannabinoids; Disease Outbreaks; Indazoles; New York City; Valine | 2017 |
Stability of Synthetic Cannabinoids in Biological Specimens: Analysis Through Liquid Chromatography Tandem Mass Spectrometry.
Topics: Blood Specimen Collection; Cannabinoids; Humans; Indazoles; Indoles; Limit of Detection; Substance Abuse Detection; Valine | 2017 |
Determination of AB-CHMINACA and its metabolites in human hair and their deposition in hair of abusers.
Topics: Chromatography, Liquid; Hair; Humans; Indazoles; Reproducibility of Results; Republic of Korea; Substance Abuse Detection; Tandem Mass Spectrometry; Valine | 2017 |
Analytical confirmation of synthetic cannabinoids in a cohort of 179 presentations with acute recreational drug toxicity to an Emergency Department in London, UK in the first half of 2015.
Topics: Adamantane; Adolescent; Adult; Aged; Cannabinoid Receptor Antagonists; Cohort Studies; Drug Overdose; Emergency Service, Hospital; Female; Humans; Illicit Drugs; Indazoles; Indoles; London; Male; Middle Aged; Prospective Studies; Substance Abuse Detection; Tandem Mass Spectrometry; Valine; Young Adult | 2017 |
AB-CHMINACA-induced sudden death from non-cardiogenic pulmonary edema.
Topics: Adult; Autopsy; Brain; Brain Stem; Cannabinoids; Death, Sudden; Designer Drugs; Fatal Outcome; Humans; Hypoxia, Brain; Indazoles; Male; Myocardium; Pulmonary Edema; Valine | 2018 |
New psychoactive substances: Studies on the metabolism of XLR-11, AB-PINACA, FUB-PB-22, 4-methoxy-α-PVP, 25-I-NBOMe, and meclonazepam using human liver preparations in comparison to primary human hepatocytes, and human urine.
Topics: Benzodiazepinones; Butyrophenones; Cannabinoids; Hepatocytes; Humans; Indazoles; Indoles; Liver; Microsomes, Liver; Molecular Structure; Phenethylamines; Psychotropic Drugs; Pyrrolidines; Quinolines; Valine | 2017 |
Acute side effects after consumption of the new synthetic cannabinoids AB-CHMINACA and MDMB-CHMICA.
Topics: Adolescent; Adult; Cannabinoids; Child; Emergency Service, Hospital; Female; Humans; Illicit Drugs; Indazoles; Indoles; Male; Middle Aged; Prospective Studies; Valine; Young Adult | 2018 |
Three fatalities associated with the synthetic cannabinoids 5F-ADB, 5F-PB-22, and AB-CHMINACA.
Topics: Adult; Blood Alcohol Content; Brain Edema; Cannabinoids; Chromatography, High Pressure Liquid; Designer Drugs; Humans; Indazoles; Indoles; Male; Mass Spectrometry; Pulmonary Edema; Quinolines; Substance Abuse Detection; Substance-Related Disorders; Valine | 2017 |
Synthetic Cannabinoid and Mitragynine Exposure of Law Enforcement Agents During the Raid of an Illegal Laboratory - Nevada, 2014.
Topics: Adult; Cannabinoids; Designer Drugs; Drug and Narcotic Control; Humans; Indazoles; Laboratories; Law Enforcement; Male; Middle Aged; Nevada; Occupational Exposure; Personal Protective Equipment; Secologanin Tryptamine Alkaloids; Valine | 2017 |
Analysis of the pharmacological properties of JWH-122 isomers and THJ-2201, RCS-4 and AB-CHMINACA in HEK293T cells and hippocampal neurons.
Topics: Cannabinoids; HEK293 Cells; Hippocampus; Humans; Indazoles; Indoles; Isomerism; Naphthalenes; Neurons; Valine | 2018 |
Functional effects of synthetic cannabinoids versus Δ
Topics: Animals; Anxiety; Body Temperature; Depression; Dronabinol; Indazoles; Male; Maze Learning; Memory; Mice, Inbred ICR; Motor Activity; Nociception; Psychotropic Drugs; Sensory Thresholds; Valine | 2019 |
Molecular and Behavioral Pharmacological Characterization of Abused Synthetic Cannabinoids MMB- and MDMB-FUBINACA, MN-18, NNEI, CUMYL-PICA, and 5-Fluoro-CUMYL-PICA.
Topics: 1-Naphthylamine; Animals; Cannabinoids; CHO Cells; Cricetulus; Cyclic AMP; HEK293 Cells; Humans; Illicit Drugs; Indazoles; Male; Mice; Mice, Inbred C57BL; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Signal Transduction; Valine | 2018 |
A case of intoxication with a mixture of synthetic cannabinoids EAM-2201, AB-PINACA and AB-FUBINACA, and a synthetic cathinone α-PVP.
Topics: Alkaloids; Autopsy; Cannabinoids; Forensic Medicine; Humans; Indazoles; Indoles; Kidney; Liver; Lung; Male; Naphthalenes; Pentanones; Pyrrolidines; Tissue Distribution; Valine | 2018 |
Convulsant Effects of Abused Synthetic Cannabinoids JWH-018 and 5F-AB-PINACA Are Mediated by Agonist Actions at CB1 Receptors in Mice.
Topics: Animals; Convulsants; Dose-Response Relationship, Drug; Humans; Illicit Drugs; Indazoles; Indoles; Male; Mice; Microsomes, Liver; Naphthalenes; Receptor, Cannabinoid, CB1; Seizures; Valine | 2019 |
Testing for AB-PINACA in human hair: Distribution in head hair versus pubic hair.
Topics: Adult; Cannabinoid Receptor Agonists; Chromatography, Liquid; Hair; Humans; Illicit Drugs; Indazoles; Limit of Detection; Male; Reproducibility of Results; Substance Abuse Detection; Tandem Mass Spectrometry; Valine | 2019 |
A case of 5F-ADB / FUB-AMB abuse: Drug-induced or drug-related death?
Topics: Adolescent; Cannabinoids; Designer Drugs; Drug Overdose; Humans; Indazoles; Liquid-Liquid Extraction; Lung; Male; Respiratory Insufficiency; Substance-Related Disorders; Valine | 2019 |
A curious case of cannabinoid toxicity.
Topics: Adult; Cannabinoids; Child, Preschool; Dietary Exposure; Female; Foodborne Diseases; Humans; Indazoles; Indoles; Male; Middle Aged; Valine; Young Adult | 2019 |
Do you feel it now? Route of administration and Δ
Topics: Administration, Inhalation; Aerosols; Animals; Behavior, Animal; Cannabinoids; Conditioning, Operant; Cyclohexanols; Electronic Nicotine Delivery Systems; Female; Indazoles; Injections, Intraperitoneal; Male; Mice, Inbred C57BL; Valine; Vaping | 2019 |
Aspects related to analysis and medico-legal assessment in the context of the presence of synthetic cannabinoids in biological material based on the example of AB-CHMINACA.
Topics: Adolescent; Aortic Valve; Aortic Valve Insufficiency; Autopsy; Forensic Medicine; Forensic Toxicology; Humans; Indazoles; Male; Substance Abuse Detection; Valine | 2018 |
Comprehensive investigation on synthetic cannabinoids: Metabolic behavior and potency testing, using 5F-APP-PICA and AMB-FUBINACA as model compounds.
Topics: Cannabinoids; Hepatocytes; Humans; Indazoles; Metabolic Networks and Pathways; Psychotropic Drugs; Tandem Mass Spectrometry; Valine | 2019 |
Do Toxic Synthetic Cannabinoid Receptor Agonists Have Signature in Vitro Activity Profiles? A Case Study of AMB-FUBINACA.
Topics: beta-Arrestins; Cannabinoid Receptor Agonists; Cyclic AMP; HEK293 Cells; Humans; Indazoles; Phosphorylation; Signal Transduction; Valine | 2019 |
Discovery of Orexant and Anorexant Agents with Indazole Scaffold Endowed with Peripheral Antiedema Activity.
Topics: Animals; Disease Models, Animal; Edema; Feeding Behavior; Indazoles; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Molecular Structure; Rats; Receptors, Cannabinoid; Rimonabant; Valine; Zymosan | 2019 |
Case Report: Synthetic Cannabinoid Deaths in State of Florida Prisoners.
Topics: Cannabinoids; Chromatography, Liquid; Drug Overdose; Florida; Forensic Toxicology; Humans; Illicit Drugs; Indazoles; Prisoners; Substance Abuse Detection; Synthetic Drugs; Valine | 2020 |
Extraordinary long detection window of a synthetic cannabinoid metabolite in human urine - Potential impact on therapeutic decisions.
Topics: Adult; Humans; Indazoles; Male; Mass Spectrometry; Molecular Structure; Substance Abuse Detection; Time Factors; Valine | 2020 |
The phenomenon of para-Fluorophenylpiperazine (pFPP) in combination with the synthetic cannabinoid AMB-FUBINACA in seized plant material in New Zealand.
Topics: Cannabinoids; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Indazoles; New Zealand; Piperazines; Plants; Psychotropic Drugs; Valine | 2020 |
In Vivo Metabolites of AB-PINACA in Solid Tissues Obtained from Its Abuser: Comparison with In Vitro Experiment.
Topics: Autopsy; Body Fluids; Cannabinoids; Chromatography, Liquid; Gas Chromatography-Mass Spectrometry; Hepatocytes; Humans; Illicit Drugs; Indazoles; Microsomes, Liver; Substance Abuse Detection; Tandem Mass Spectrometry; Valine | 2021 |
Assessment of synthetic cannabinoid FUB-AMB and its ester hydrolysis metabolite in human liver microsomes and human blood samples using UHPLC-MS/MS.
Topics: Adult; Chromatography, High Pressure Liquid; Esters; Forensic Toxicology; Humans; Hydrolysis; Indazoles; Male; Microsomes, Liver; Middle Aged; Tandem Mass Spectrometry; Valine; Young Adult | 2020 |
Evaluation of Synthetic Cannabinoid Metabolites in Human Blood in the Absence of Parent Compounds: A Stability Assessment.
Topics: Cannabinoids; Chromatography, Liquid; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Indazoles; Mass Spectrometry; Substance Abuse Detection; Valine | 2021 |
Sex-dependent pharmacological profiles of the synthetic cannabinoid MMB-Fubinaca.
Topics: Animals; Brain; Cannabinoids; Female; HEK293 Cells; Humans; Indazoles; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Sex Factors; Valine | 2021 |
A Systematic Study of the In Vitro Pharmacokinetics and Estimated Human In Vivo Clearance of Indole and Indazole-3-Carboxamide Synthetic Cannabinoid Receptor Agonists Detected on the Illicit Drug Market.
Topics: Blood Proteins; Cannabinoid Receptor Agonists; Cannabinoids; Cells, Cultured; Computer Simulation; Drug Stability; Half-Life; Hepatocytes; Humans; Illicit Drugs; Inactivation, Metabolic; Indazoles; Indoles; Microsomes, Liver; Stereoisomerism; Structure-Activity Relationship; Valine | 2021 |
In-depth comparison of the metabolic and pharmacokinetic behaviour of the structurally related synthetic cannabinoids AMB-FUBINACA and AMB-CHMICA in rats.
Topics: Animals; Cannabinoids; Indazoles; Male; Rats; Rats, Sprague-Dawley; Valine | 2022 |
Post-aggression suicide under the influence of new psychoactive substances AMB-FUBINACA and U-47700.
Topics: Aggression; Benzamides; Female; Humans; Indazoles; Male; Suicide; Tandem Mass Spectrometry; Valine | 2022 |
Defining Steric Requirements at CB
Topics: Animals; Cannabinoid Receptor Agonists; Cannabinoids; Central Nervous System Agents; Indazoles; Mice; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Valine | 2022 |
Cannabimimetic effects of abused indazole-carboxamide synthetic cannabinoid receptor agonists AB-PINACA, 5F-AB-PINACA and 5F-ADB-PINACA in mice: Tolerance, dependence and withdrawal.
Topics: Amides; Animals; Cannabinoid Receptor Agonists; Cannabinoids; Humans; Hypothermia; Indazoles; Male; Mice; Receptor, Cannabinoid, CB1; Rimonabant; Substance-Related Disorders; Tremor; Valine | 2022 |
Convulsant doses of abused synthetic cannabinoid receptor agonists AB-PINACA, 5F-AB-PINACA, 5F-ADB-PINACA and JWH-018 do not elicit electroencephalographic (EEG) seizures in male mice.
Topics: Animals; Benzodiazepines; Cannabinoid Receptor Agonists; Cannabinoids; Convulsants; Diazepam; Electroencephalography; Humans; Indazoles; Indoles; Male; Mice; Naphthalenes; Pentylenetetrazole; Receptor, Cannabinoid, CB1; Rimonabant; Seizures; Substance-Related Disorders; Valine | 2022 |