indazoles has been researched along with glycine in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 1 (5.00) | 29.6817 |
| 2010's | 12 (60.00) | 24.3611 |
| 2020's | 6 (30.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kahn, RA; Panah, M; Weinberger, J | 1 |
| Fritz, KI; Haider, SH; Mishra, OP; Papadopoulos, MD; Parikh, N; Sorrentino, DF | 1 |
| Beraldi, E; Fazli, L; Gleave, ME; Kuruma, H; Lamoureux, F; Thomas, C; Yin, MJ; Zoubeidi, A | 1 |
| Alarcon, SV; Brega, N; Crandon, S; Figg, WD; Giaccone, G; Gutierrez, M; Houk, BE; Jain, L; Kelly, RJ; Kim, YS; Kummar, S; Mannargudi, B; Rajan, A; Shnaidman, M; Trepel, JB; Zein, WM | 1 |
| Brega, N; Hinson, JM; Houk, BE; Jillela, A; Reddy, N; Voorhees, PM | 1 |
| Chrysikos, D; Dimopoulos, MA; Papadimitriou, CA; Psaltopoulou, T; Sergentanis, TN; Zagouri, F | 1 |
| Bryant, C; Debnath, A; Eckmann, L; Gut, J; Hirata, K; Hwang, G; McKerrow, JH; Miyamoto, Y; Pillai, DR; Reed, SL; Renslo, AR; Shahinas, D | 1 |
| Bauer, TM; Bendell, JC; Burris, HA; Hinson, JM; Infante, JR; Jones, S; Orlemans, EO; Ramanathan, RK; Tibes, R; Von Hoff, DD; Weiss, GJ | 1 |
| Akare, UR; Bandaru, S; Dunna, NR; Gutlapalli, VR; Nayarisseri, A; Rajadhyax, S; Yadav, M | 1 |
| Arán, VJ; Marín, C; Muro, B; Navarro, P; Ramírez-Macías, I; Reviriego, F; Rosales, MJ; Sánchez-Moreno, M | 1 |
| Choi, MG; Ihm, SH; Kang, JG; Kim, CS; Kim, SH; Lee, SJ; Yoo, HJ | 1 |
| Cheng, B; Huang, C; Qian, SL; Sun, LY | 1 |
| Augelli-Szafran, C; Boddu, R; Kelly, K; Liu, Z; Moukha-Chafiq, O; Wang, S; West, AB | 1 |
| Jin, X; Lv, H; Zhang, Z; Zhou, J | 1 |
| Broaddus, R; Fu, S; Hess, K; Hong, D; Janku, F; Karp, D; Kopetz, S; Liu, L; Naing, A; Overman, M; Piha-Paul, S; Shi, N; Subbiah, V; Tsimberidou, AM; Wang, Y; Yao, J | 1 |
| Chen, L; Cheng, S; Li, B; Lin, Z; Wang, M; Wang, W; Yao, M; Yin, Q; Zhang, Y | 1 |
| Cho, YK; Choi, MG; Huh, JH; Ihm, SH; Kang, JG; Kim, SH; Lee, SJ | 1 |
| Damanaki, A; Deschner, J; Jantsch, J; Kirschneck, C; Leikam, A; Memmert, S; Proff, P; Schröder, A; Spanier, G; Thuy, M | 1 |
| Alinari, L; Baiocchi, RA; Byrd, JC; Chen, TL; Harrington, B; Hertlein, E; Lehman, AM; Orlemans, E; Prouty, A; Sampath, D; Sloan, S; Truxall, J; Wasmuth, R; Woyach, JA | 1 |
| Albakova, Z; Mangasarova, Y; Sapozhnikov, A | 1 |
2 review(s) available for indazoles and glycine
| Article | Year |
|---|---|
Hsp90 inhibitors in breast cancer: a systematic review.
Topics: Adenine; Antineoplastic Agents; Benzamides; Benzoquinones; Biomarkers, Tumor; Female; Glycine; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Indazoles; Isoxazoles; Lactams, Macrocyclic; Pyridines; Resorcinols; Triazoles; Triple Negative Breast Neoplasms | 2013 |
Heat Shock Proteins in Lymphoma Immunotherapy.
Topics: Animals; Benzamides; Benzodioxoles; Glycine; Heat-Shock Proteins; Humans; Immunotherapy; Immunotherapy, Adoptive; Indazoles; Isoxazoles; Lymphoma; Molecular Targeted Therapy; Purines; Resorcinols | 2021 |
4 trial(s) available for indazoles and glycine
| Article | Year |
|---|---|
A phase I study of PF-04929113 (SNX-5422), an orally bioavailable heat shock protein 90 inhibitor, in patients with refractory solid tumor malignancies and lymphomas.
Topics: Adult; Aged; Benzamides; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Glycine; HSP90 Heat-Shock Proteins; Humans; Indazoles; Lymphoma; Male; Middle Aged; Neoplasms | 2011 |
Phase I trial of the HSP90 inhibitor PF-04929113 (SNX5422) in adult patients with recurrent, refractory hematologic malignancies.
Topics: Adult; Aged; Aged, 80 and over; Benzamides; Cohort Studies; Disease Progression; Dose-Response Relationship, Drug; Female; Glycine; Hematologic Neoplasms; HSP90 Heat-Shock Proteins; Humans; Indazoles; Male; Middle Aged; Neoplasm Recurrence, Local; Young Adult | 2013 |
Phase I dose-escalation studies of SNX-5422, an orally bioavailable heat shock protein 90 inhibitor, in patients with refractory solid tumours.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anemia; Antineoplastic Agents; Benzamides; Biological Availability; Diarrhea; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Glycine; Heterocyclic Compounds, 4 or More Rings; HSP90 Heat-Shock Proteins; Humans; Indazoles; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Prodrugs; Vision Disorders | 2014 |
Phase I studies of vorinostat with ixazomib or pazopanib imply a role of antiangiogenesis-based therapy for TP53 mutant malignancies.
Topics: Adult; Aged; Angiogenesis Inhibitors; Boron Compounds; Glycine; Humans; Indazoles; Kaplan-Meier Estimate; Middle Aged; Mutation; Neoplasms; Progression-Free Survival; Pyrimidines; Sulfonamides; Treatment Outcome; Tumor Suppressor Protein p53; Vorinostat; Young Adult | 2020 |
14 other study(ies) available for indazoles and glycine
| Article | Year |
|---|---|
Modulation of ischemic excitatory neurotransmitter and gamma-aminobutyric acid release during global temporary cerebral ischemia by selective neuronal nitric oxide synthase inhibition.
Topics: Animals; Aspartic Acid; Brain; Brain Ischemia; Excitatory Amino Acids; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Indazoles; Male; Microdialysis; Neurons; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 1997 |
Nitric oxide-mediated modification of the glycine binding site of the NMDA receptor during hypoxia in the cerebral cortex of the newborn piglet.
Topics: Animals; Animals, Newborn; Binding Sites; Cerebral Cortex; Enzyme Inhibitors; Glycine; Hypoxia; Indazoles; Nitric Oxide; Nitric Oxide Synthase; Receptors, N-Methyl-D-Aspartate; Swine | 2004 |
Clusterin inhibition using OGX-011 synergistically enhances Hsp90 inhibitor activity by suppressing the heat shock response in castrate-resistant prostate cancer.
Topics: Animals; Apoptosis; Benzamides; Benzoquinones; Cell Line, Tumor; Clusterin; Drug Synergism; Glycine; Heat-Shock Response; HSP90 Heat-Shock Proteins; Humans; Indazoles; Lactams, Macrocyclic; Male; Mice; Mice, Nude; Prostatic Neoplasms; Thionucleotides; Xenograft Model Antitumor Assays | 2011 |
Hsp90 inhibitors as new leads to target parasitic diarrheal diseases.
Topics: Anilino Naphthalenesulfonates; Animals; Antiprotozoal Agents; Benzamides; Cell Line, Tumor; Disease Models, Animal; Entamoeba histolytica; Entamoebiasis; Giardia lamblia; Giardiasis; Glycine; HSP90 Heat-Shock Proteins; Humans; Indazoles; Jurkat Cells; Mice; Parasitic Sensitivity Tests; Trophozoites | 2014 |
Multiclass comparative virtual screening to identify novel Hsp90 inhibitors: a therapeutic breast cancer drug target.
Topics: Adenine; Anisoles; Antineoplastic Agents; Benzamides; Binding Sites; Breast Neoplasms; Catechin; Databases, Chemical; Drug Discovery; Female; Gene Expression; Glycine; Heterocyclic Compounds, 2-Ring; High-Throughput Screening Assays; HSP90 Heat-Shock Proteins; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Indazoles; Ligands; Molecular Docking Simulation; Protein Binding; Pyrazoles; Pyridines; Static Electricity; Structure-Activity Relationship; User-Computer Interface | 2015 |
In vitro leishmanicidal activity of 1,3-disubstituted 5-nitroindazoles.
Topics: Acetates; Alanine; Animals; Antiprotozoal Agents; Glycine; In Vitro Techniques; Indazoles; Lactic Acid; Leishmania braziliensis; Leishmania infantum; Leishmaniasis, Visceral; Macrophages; Magnetic Resonance Spectroscopy; Mice; Microscopy, Electron, Transmission; Mitochondria; Organelles; Pyruvic Acid; Succinic Acid | 2015 |
The heat shock protein 90 inhibitor SNX5422 has a synergistic activity with histone deacetylase inhibitors in induction of death of anaplastic thyroid carcinoma cells.
Topics: Antineoplastic Agents; Apoptosis; Benzamides; Caspase 3; Cell Line, Tumor; Cell Survival; Drug Synergism; Glycine; Histone Deacetylase Inhibitors; HSP90 Heat-Shock Proteins; Humans; Hydroxamic Acids; Indazoles; Phosphorylation; Proto-Oncogene Proteins c-akt; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Vorinostat | 2016 |
Light-Emitting Diode Irradiation (640 nm) Regulates Keratinocyte Migration and Cytoskeletal Reorganization Via Hypoxia-Inducible Factor-1α.
Topics: Adult; Blotting, Western; Cell Movement; Cell Proliferation; Child; Cobalt; Cytoskeleton; Foreskin; Glycine; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Indazoles; Keratinocytes; Low-Level Light Therapy; Male; Up-Regulation | 2016 |
The G2019S mutation in LRRK2 imparts resiliency to kinase inhibition.
Topics: Adenosine Triphosphate; Animals; Brain; Female; Glycine; Humans; Indazoles; Kidney; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Lung; Lysosomes; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Protein Kinase Inhibitors; Pyrimidines; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Serine | 2018 |
Doxorubicin combined with betulinic acid or lonidamine in RGD ligand-targeted pH-sensitive micellar system for ovarian cancer treatment.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Arginine; Aspartic Acid; Betulinic Acid; Cell Line, Tumor; Doxorubicin; Drug Carriers; Drug Compounding; Drug Liberation; Female; Glycine; Humans; Hydrogen-Ion Concentration; Indazoles; Leukocyte Count; Ligands; Mice; Micelles; Oligopeptides; Ovarian Neoplasms; Pentacyclic Triterpenes; Tissue Distribution; Triterpenes; Xenograft Model Antitumor Assays | 2019 |
Mild microwave ablation combined with HSP90 and TGF‑β1 inhibitors enhances the therapeutic effect on osteosarcoma.
Topics: Animals; Apoptosis; Benzamides; Bone Neoplasms; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Glycine; HSP90 Heat-Shock Proteins; Humans; Imidazoles; Indazoles; Microwaves; Osteosarcoma; Quinoxalines; Rabbits; Radiofrequency Ablation; Transforming Growth Factor beta1; Tumor Burden | 2020 |
Heat Shock Protein 90 Inhibitors AUY922, BIIB021 and SNX5422 Induce Bim-mediated Death of Thyroid Carcinoma Cells.
Topics: Adenine; Apoptosis; Bcl-2-Like Protein 11; Benzamides; Cell Line, Tumor; Cell Survival; Extracellular Signal-Regulated MAP Kinases; Glycine; HSP90 Heat-Shock Proteins; Humans; Indazoles; Isoxazoles; Proto-Oncogene Proteins c-akt; Pyridines; Resorcinols; Signal Transduction; Thyroid Neoplasms | 2020 |
Role and Regulation of Mechanotransductive HIF-1α Stabilisation in Periodontal Ligament Fibroblasts.
Topics: Adolescent; Adult; Cells, Cultured; Female; Fibroblasts; Focal Adhesion Kinase 1; Genistein; Glycine; Glycosaminoglycans; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Indazoles; Integrins; Male; Mechanotransduction, Cellular; Periodontal Ligament; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Protein Stability; Signal Transduction; Stress, Mechanical; Tooth Movement Techniques; Urea; Vascular Endothelial Growth Factor A | 2020 |
Preclinical evaluation of the Hsp90 inhibitor SNX-5422 in ibrutinib resistant CLL.
Topics: Adenine; Animals; Antineoplastic Agents; Benzamides; Cell Line, Tumor; Drug Resistance, Neoplasm; Glycine; HSP90 Heat-Shock Proteins; Humans; Indazoles; Leukemia, Lymphocytic, Chronic, B-Cell; Mice; Piperidines; Protein Kinase Inhibitors | 2021 |