indazoles has been researched along with arginine in 163 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 48 (29.45) | 18.2507 |
| 2000's | 74 (45.40) | 29.6817 |
| 2010's | 39 (23.93) | 24.3611 |
| 2020's | 2 (1.23) | 2.80 |
| Authors | Studies |
|---|---|
| Friedlander, MJ; Gancayco, CD; Marchase, RB; Montague, PR; Winn, MJ | 1 |
| Davis, W; Penix, LP; Subramaniam, S | 1 |
| Allawi, HS; Bland-Ward, PA; Gaffen, Z; Moore, PK; Pitcher, A; Wallace, P | 1 |
| Balla, I; Dawson, TM; Kovách, AG; Lohinai, Z; Marczis, J; Snyder, SH | 1 |
| Brain, SD; Kajekar, R; Moore, PK | 1 |
| Klatt, P; Mayer, B; Schmidt, K; Werner, ER | 1 |
| Dalkara, T; Irikura, K; Moskowitz, MA; Yoshida, T | 1 |
| Blauw, GJ; Bruning, TA; Chang, PC; van Zwieten, PA; Vermeij, P | 1 |
| Babbedge, RC; Gaffen, Z; Hart, SL; Moore, PK; Wallace, P | 1 |
| Dray, A; Patel, IA; Rueff, A; Urban, L | 1 |
| Fitzgerald, ME; Reiner, A; Sancesario, G; Zagvazdin, YS | 1 |
| Anwyl, R; Doyle, C; Hölscher, C; Rowan, MJ | 1 |
| Southan, GJ; Szabó, C | 1 |
| Giovanelli, J; Kaufman, S; Witteveen, CF | 1 |
| Castagliuolo, I; LaMont, JT; Nikulasson, Z; Pothoulakis, C; Qiu, B | 1 |
| Allix, M; Boulu, RR; Mésenge, C; Plotkine, M; Verrecchia, C | 2 |
| Kimes, AS; London, ED; Vaupel, DB | 1 |
| Bland-Ward, PA; Moore, PK | 1 |
| Fitzgerald, ME; Reiner, A; Sancesario, G; Share, L; Wang, YX; Zagvazdin, Y | 1 |
| Erik, A; Persson, G; Thorup, C | 1 |
| Chapman, AG; Man, CM; Meldrum, BS; Smith, SE; Tang, E; Yip, PK | 1 |
| Dickenson, AH; Misra, C; Stanfa, LC | 1 |
| Curtis, MJ; Pabla, R | 1 |
| Czachurski, J; Seller, H; Zanzinger, J | 1 |
| Cespuglio, R; Chouvet, G; Desvignes, C; Lambás-Señas, L; Renaud, B; Robert, F; Vachette, C | 1 |
| Bowen, SE; Golden, KM; Wiley, JL | 1 |
| Borowicz, KK; Czuczwar, SJ; Kleinrok, Z | 1 |
| Bryan, RM; Childres, WF; Curling, PE; Ignacio, CS | 1 |
| Erden, BF; Kayaalp, SO; Tapanyigit, EE; Uzbay, IT | 1 |
| Hsu, KS; Huang, CC | 1 |
| Erden, BF; Gacar, N; Ulak, G; Yildiran, G | 1 |
| Ayata, C; Huang, PL; Meng, W; Moskowitz, MA; Waeber, C | 1 |
| Conte, A; Ottaviani, E | 1 |
| Bitterman, H; Bitterman, N | 1 |
| Alderton, WK; Boyhan, A; Lowe, PN | 1 |
| Hindmarsh, JG; Jenner, P; Marsden, CD; Rose, S; Silva, MT | 1 |
| Hölscher, C | 1 |
| Adams, JM; Horstman, DJ; Patel, GM; Rich, GF | 1 |
| Bartos, S; Benedek, G; Horváth, G; Szikszay, M | 1 |
| Choate, JK; Paterson, DJ; Sears, CE | 1 |
| Cox, BA; Johnson, SW | 1 |
| Hu, WH; Jen, MF; Li, F; Liao, WH; Liu, JS; Liu, N; Qiang, WA; Wang, GQ; Xiao, J | 1 |
| Sugimoto, Y; Yamada, J; Yoshikawa, T | 1 |
| Alabadí, JA; Lasbennes, F; Pinard, E; Seylaz, J; Thibault, JL | 1 |
| Brown, RE; Podhorna, J | 1 |
| Cheng, KK; Lin, HC; Tseng, CJ; Wan, FJ | 1 |
| Hedrick, MS; Morales, RD | 1 |
| Erden, BF; Gacar, N; Ulak, G; Yildiz, F | 1 |
| Endo, T; Hara, S; Kano, S; Kuriiwa, T; Kurosaki, K; Mukai, T; Yanase, T | 1 |
| De Sarro, A; De Sarro, G; Falconi, U; Gareri, P | 1 |
| Cooper, JC; Kitto, KF; Kovacs, KJ; Larson, AA | 1 |
| Erden, BF; Gacar, N; Ulak, G; Utkan, T; Yildiz, F | 1 |
| Rosenberg, R; Volke, V; Wegener, G | 1 |
| Battisti, JJ; Shreffler, CB; Uretsky, NJ; Wallace, LJ | 1 |
| Bandpey, Z; Rosenberg, R; Volke, V; Wegener, G | 1 |
| Chen, QH; Horiuchi, J; Nishida, Y; Tandai-Hiruma, M; Terada, S | 1 |
| Kontos, HA; Rosenblum, WI; Wei, EP | 1 |
| Boulouard, M; Collot, V; Dauphin, F; Duval, D; Gsell, W; Hommet, Y; MacKenzie, ET; Rault, S; Schumann, P; Sopkova, J | 1 |
| Koss, MC; Roberts, ZV | 1 |
| Ayajiki, K; Fujioka, H; Okamura, T; Toda, N | 1 |
| Haberle, D; Halász, AS; Magyar, K; Szökõ, E; Tekes, K | 1 |
| Che, Y; Han, PL; Lee, JK; Piao, CS | 1 |
| Hickey, MJ; Huang, PL; Johnston, B; Kubes, P; McCafferty, DM; Raharjo, E; Sanz, MJ | 1 |
| Dikshit, M; Sethi, S; Sharma, P | 1 |
| Longhurst, JC; Phan, NT; Tjen-A-Looi, SC | 1 |
| Wang, XY; Zhang, JT | 1 |
| Morato, GS; Wazlawik, E | 1 |
| Alajuuma, P; Kotikoski, H; Laippala, P; Moilanen, E; Oksala, O; Salmenperä, P; Vapaatalo, H | 1 |
| Ralevic, V | 1 |
| Heiberg, IL; Rosenberg, R; Wegener, G | 1 |
| Araki, T; Imai, Y; Itoyama, Y; Kato, H; Kurosaki, R; Matsubara, M; Michimata, M; Mikami, T; Muramatsu, Y | 1 |
| Jeong, MS; Kim, CJ; Kim, KW; Park, EY; Park, JW; Shin, BS; Shin, MS; Woo, RS; Zhao, RJ | 1 |
| Banerjee, B; Masood, A; Ray, A; Vijayan, VK | 1 |
| Burk, M; Harris, MB; Lukowiak, K; Remmers, JE; Smyth, K; Taylor, BE | 1 |
| Kikelj, D; Mlinsek, G; Peterlin-Masic, L; Solmajer, T; Stegnar, M; Trampus-Bakija, A | 1 |
| Bourin, M; Vasar, E; Volke, V; Wegener, G | 1 |
| Hung, CC; Lee, SY; Li, SY; Lin, MJ; Lin, RH; Lin-Shiau, SY; Su, CC; Su, MC; Tan, CT | 1 |
| Sagami, I; Shimizu, T; Yadav, J | 1 |
| Ogonowski, AA; Smith, JB | 1 |
| Caffrey, JL; Farias, M; Jackson, K; Johnson, M | 1 |
| Bell, PD; Fuson, A; Komlósi, P; Kovács, G; Peti-Peterdi, J; Rosivall, L | 1 |
| Li, ZQ; Shi, Y; Wang, NQ; Wu, ZH | 1 |
| Chelly, JE; Doursout, MF; Liang, Y | 1 |
| Boucher, JL; Collot, V; Frapart, Y; Pérollier, C; Rault, S; Schumann-Bard, P; Tuynman, A | 1 |
| Mahajan, P; Mediratta, PK; Reeta, KH; Sharma, KK | 1 |
| Dietz, S; Faurie, F; Gross, R; Lajoix, AD; Linck, N; Mani, JC; Petit, P; Pugnière, M; Ribes, G; Roquet, F | 1 |
| Banerji, B; Masood, A; Ray, A; Vijayan, VK | 1 |
| Li, J; Mitchell, JH; Smith, SA | 1 |
| Gibson, DM; Kers, JA; Krasnoff, SB; Loria, R; Wach, MJ | 1 |
| Fowler, L; Pearce, B; Watts, J; Whitton, PS | 1 |
| Calderón-Cortés, E; Clemente-Guerrero, M; Cortés-Rojo, C; Gaona-Zamudio, FJ; Saavedra-Molina, A; Sierra-Campos, E; Villalobos-Molina, R | 1 |
| de Oliveira, RM; Forestiero, D; Guimarães, FS; Manfrim, CM | 1 |
| Dehpour, AR; Ghahremani, MH; Riazi, K; Tahsili-Fahadan, P; Yahyavi-Firouz-Abadi, N | 1 |
| Richter, A; Sander, SE | 1 |
| Engelhardt, T; Galley, HF; Lowe, PR; Webster, NR | 1 |
| Guimarães, FS; Joca, SR | 1 |
| Carletti, F; D'Agostino, S; Ferraro, G; Rizzo, V; Sardo, P | 1 |
| D'Alecy, LG; Song, MY; Whitesall, SE; Zwemer, CF | 1 |
| Coelho, RC; Fighera, MR; Fiorenza, NG; Furian, AF; Mello, CF; Oliveira, MS; Petry, JC; Royes, LF | 1 |
| Blevins, DE; Drummond, JT; Lutz, MC; Nickels, TJ; Reed, GW; Wilson, DF | 1 |
| Gourgoulianis, KI; Hatziefthimiou, AA; Kitsiopoulou, E; Molyvdas, PA | 1 |
| Castrignanò, S; Colaianna, M; Cuomo, V; De Giorgi, A; Govoni, S; Kendrick, KM; Lanni, C; Schiavone, S; Trabace, L | 1 |
| Dhir, A; Kulkarni, SK | 2 |
| da-Silva, CA; Del Bel, EA; Echeverry, MB; Ferreira, FR; Salgado, ML | 1 |
| Erden, F; Gacar, N; Tanyeri, P; Ulak, G; Utkan, T; Yildiz Akar, F | 1 |
| Ferraro, G; Sardo, P | 1 |
| Agar, E; Ayyildiz, M; Bosnak, M; Yildirim, M | 1 |
| Guimarães, FS; Kanamaru, F; Oliveira, RM; Spiacci, A | 1 |
| Carletti, F; D'Agostino, S; Ferraro, G; La Grutta, V; Rizzo, V; Sardo, P | 1 |
| Brown, RD; Carlström, M; Edlund, J; Larsson, E; Palm, F; Persson, AE; Sällström, J; Teerlink, T; Wåhlin, N | 1 |
| Gao, Y; Wang, WJ; Zou, XM | 1 |
| Bagirici, F; Bostanci, MO; Gulturk, S; Kozan, R; Sefil, F | 1 |
| Akula, KK; Dhir, A; Kulkarni, SK | 1 |
| Bloudickova, S; Bokodi, G; Fekete, A; Heemann, U; Müller, V; Rajnoch, J; Reusz, G; Rusai, K; Szabó, A; Szabó, AJ; Szebeni, B; Tulassay, T; Vannay, A; Viklicky, O | 1 |
| Acierno, R; Amelio, D; Gattuso, A; Guerrieri, A; Mannarino, C; Tota, B | 1 |
| Fernández-Guasti, A; Jiménez-Velázquez, G; López-Muñoz, FJ | 1 |
| Chiu, YT; Gong, CL; Kuo, JS; Lee, TJ; Li, HT; Lin, NN; Tsai, TT | 1 |
| Brocardo, Pde S; Budni, J; Kaster, MP; Lobato, KR; Rodrigues, AL | 1 |
| Aydin, C; Bagcivan, I; Koyuncu, A; Ozer, H; Soylu, S; Topcu, O; Yildirim, S | 1 |
| Carletti, F; D'Agostino, S; Ferraro, G; Lonobile, G; Rizzo, V; Sardo, P | 1 |
| Celikyurt, IK; Mutlu, O; Ulak, G; Yildiz Akar, F | 1 |
| Agar, E; Ayyildiz, M; Yildirim, M | 1 |
| Agar, E; Aslan, A; Ayyildiz, M; Güven, A; Yildirim, M | 1 |
| Bahremand, A; Dehpour, AR; Hedayat, T; Nasrabady, SE; Payandemehr, B; Rahimian, R; Ziai, P | 1 |
| Benigno, A; Crescimanno, G; Di Giovanni, G; Di Matteo, V; Esposito, E; Pierucci, M | 1 |
| Bahremand, A; Dehpour, AR; Ghasemi, A; Ghasemi, M; Hedayat, T; Khodadad, TK; Payandemehr, B; Rahimian, R; Ziai, P | 1 |
| Krass, M; Rünkorg, K; Volke, V; Wegener, G | 1 |
| Chandramohan, N; Ljunggren-Rose, A; Sriram, S; Whetsell, WO; Yao, SY | 1 |
| Andreatini, R; Chioca, LR; Correia, D; Pereira, M; Pizzolatti, MG; Santos, AR; Siba, IP; Vital, MA | 1 |
| Balen, Gde O; Budni, J; Fernandes, SC; Freitas, AE; Moretti, M; Rodrigues, AL | 1 |
| Aricioglu, F; Gacar, N; Gocmez, SS; Komsuoglu-Celikyurt, I; Mutlu, O; Utkan, T | 1 |
| Ender, M; Galli, P; Madon, J; Riewald, M; Schuepbach, RA | 1 |
| Chien, SJ; Hsu, CN; Huang, CF; Huang, LT; Lin, YJ; Tain, YL | 1 |
| Abdel-Hady, RH; Abdel-Zaher, AO; Farghaly, HS; Hamdy, MM; Mostafa, MG | 1 |
| Echizenya, S; Honda, K; Ito, R; Iwata, K; Kaji, K; Lee, J; Ohara, K; Shinoda, M; Sugiyama, T; Takahashi, O; Urata, K; Watase, T | 1 |
| Akar, F; Bektas, E; Erden, F; Komsuoglu Celikyurt, I; Mutlu, O; Tanyeri, P; Ulak, G | 1 |
| Chen, HX; Li, YF; Wang, HL; Zhang, LM; Zhang, YZ; Zhao, N | 1 |
| Llorente, J; Mendiguren, A; Pineda, J; Santamarta, MT | 1 |
| Gocmez, SS; Karadenizli, S; Sahin, D; Utkan, T; Yazir, Y | 1 |
| Fidecka, S; Listos, J; Orzelska, J; Talarek, S | 1 |
| Hosseini, M; Moezi, L; Niknahad, H; Oveisi, S; Shafaroodi, H | 2 |
| Corrêa da Silva, JA; da Silva, LM; de Souza, MM; Holzmann, I; Steimbach, VM | 1 |
| Bulani, VD; Chowdhury, AA; Gawali, NB; Juvekar, AR; Kothavade, PS; Nagmoti, DM | 1 |
| Abkhoo, A; Amiri, S; Boojar, MM; Dehpour, AR; Delazar, S; Hassanipour, M; Ostadhadi, S; Rahimi, N; Shirzadian, A | 1 |
| Dehpour, AR; Ejtemaei Mehr, S; Hassanzadeh, G; Khan, MI; Ostadhadi, S; Zolfaghari, S | 1 |
| Liao, ZL; Qiu, YJ; Tan, YF; Yu, EY; Zhu, JP | 1 |
| Demiroz, AS; Dervisoglu, S; Gokay, BV; Gokay, NS; Gokce, A; Komur, B; Yilmaz, I | 1 |
| Biala, G; Jakobczuk, M; Kotlinska, J; Listos, J; Orzelska-Gorka, J; Talarek, S | 1 |
| Andreatini, R; Bortolanza, M; da Cunha, JM; Del Bel, EA; Frazão Vital, MAB; Siba, IP; Zanoveli, JM | 1 |
| Carletti, F; Ferraro, G; Gambino, G; Rizzo, V; Sardo, P | 1 |
| Alessi, MC; Boivin, G; Couture, C; Hamelin, MÈ; Jandrot-Perrus, M; Lê, VB; Rhéaume, C; Riteau, B | 1 |
| Dehpour, AR; Moradi, A; Nikoui, V; Norouzi-Javidan, A; Ostadhadi, S; Zolfaghari, S | 1 |
| Barančík, M; Berenyiová, A; Dovinová, I; Hrabárová, E; Jansen, E; Kvandová, M; Majzúnová, M | 1 |
| Chamanara, M; Dehpour, AR; Nikoui, V; Norouzi-Javidan, A; Ostadhadi, S; Shakiba, S; Zolfaghari, S | 1 |
| Ding, L; Gao, X; Hu, J; Yu, S | 1 |
| Koizumi, K; Nabeta, R; Nakamura, Y; Oka, JI; Sasaki-Hamada, S | 1 |
| Arslan, G; Gunes, H; Ozdemir, E | 1 |
| Jin, X; Lv, H; Zhang, Z; Zhou, J | 1 |
| Auta, J; Davis, JM; Gatta, E; Guidotti, A; Pandey, SC; Zhang, H | 1 |
| Campello-Costa, P; Cossenza, M; Gladulich, LFH; Paes-de-Carvalho, R; Peixoto-Rodrigues, MC | 1 |
2 review(s) available for indazoles and arginine
| Article | Year |
|---|---|
Selective pharmacological inhibition of distinct nitric oxide synthase isoforms.
Topics: Animals; Arginase; Arginine; Brain; Endothelium, Vascular; Enzyme Inhibitors; Humans; Indazoles; Isoenzymes; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine | 1996 |
Nitric oxide synthase inhibitors. Preclinical studies of potential use for treatment of opioid withdrawal.
Topics: Adrenergic alpha-Agonists; Animals; Arginine; Blood Pressure; Clonidine; Depression, Chemical; Enzyme Inhibitors; Heart Rate; Indazoles; Morphine; Narcotics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Opioid-Related Disorders; Ornithine; Substance Withdrawal Syndrome | 1995 |
161 other study(ies) available for indazoles and arginine
| Article | Year |
|---|---|
Role of NO production in NMDA receptor-mediated neurotransmitter release in cerebral cortex.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cerebral Cortex; Glutamates; Glutamic Acid; Guinea Pigs; In Vitro Techniques; Indazoles; Male; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Norepinephrine; omega-N-Methylarginine; Potassium Chloride; Receptors, N-Methyl-D-Aspartate; Synaptosomes | 1994 |
Inhibition of NO synthase increases the severity of kainic acid-induced seizures in rodents.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bicuculline; Cerebrovascular Circulation; Enzyme Inhibitors; Indazoles; Kainic Acid; Male; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures | 1994 |
Effect of 7-nitro indazole on neurotransmission in the rat vas deferens: mechanisms unrelated to inhibition of nitric oxide synthase.
Topics: Adenosine Triphosphate; Amino Acid Oxidoreductases; Animals; Arginine; Electric Stimulation; In Vitro Techniques; Indazoles; Male; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Norepinephrine; Potassium Chloride; Propranolol; Rats; Rats, Wistar; Synaptic Transmission; Vas Deferens; Yohimbine | 1994 |
The effect of hemorrhagic hypotension and retransfusion and 7-nitro-indazole on rCBF, NOS catalytic activity, and cortical NO content in the cat.
Topics: Acetylcholine; Adenosine Triphosphate; Amino Acid Oxidoreductases; Analgesics; Animals; Arginine; Blood Pressure; Blood Transfusion; Brain; Cats; Cerebral Arteries; Cerebral Cortex; Cerebrovascular Circulation; Electroencephalography; Hemorrhage; Hypotension; Indazoles; Male; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Norepinephrine; Organ Specificity; Parietal Lobe; Pituitary Gland; Regional Blood Flow; Spinal Cord; Vasodilator Agents | 1994 |
Essential role for nitric oxide in neurogenic inflammation in rat cutaneous microcirculation. Evidence for an endothelium-independent mechanism.
Topics: Animals; Arginine; Blood Pressure; Cyclic GMP; Endothelium, Vascular; Indazoles; Inflammation; Male; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Regional Blood Flow; Skin; Substance P | 1995 |
Molecular mechanisms of inhibition of porcine brain nitric oxide synthase by the antinociceptive drug 7-nitro-indazole.
Topics: Amino Acid Oxidoreductases; Analgesics; Animals; Arginine; Binding, Competitive; Biopterins; Brain; Citrulline; Enzyme Inhibitors; Hydrogen Peroxide; Indazoles; Kinetics; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Protein Binding; Swine | 1994 |
Dual role of nitric oxide in focal cerebral ischemia.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Brain; Brain Ischemia; Cerebral Infarction; Cerebrovascular Circulation; Electroencephalography; Enzyme Inhibitors; Hemodynamics; Indazoles; Male; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 1994 |
Serotonin-induced vasodilatation in the human forearm is mediated by the "nitric oxide-pathway": no evidence for involvement of the 5-HT3-receptor.
Topics: Adult; Amino Acid Oxidoreductases; Arginine; Forearm; Free Radical Scavengers; Granisetron; Guanylate Cyclase; Humans; Indazoles; Male; Methylene Blue; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Ondansetron; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Vasodilation | 1993 |
Characterization of the novel nitric oxide synthase inhibitor 7-nitro indazole and related indazoles: antinociceptive and cardiovascular effects.
Topics: Amino Acid Oxidoreductases; Analgesics; Animals; Arginine; Blood Pressure; Cardiovascular Agents; Cerebellum; Enzyme Inhibitors; Formaldehyde; In Vitro Techniques; Indazoles; Male; Mice; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Pain Measurement; Rabbits; Rats | 1993 |
Regulation of bradykinin sensitivity in peripheral sensory fibres of the neonatal rat by nitric oxide and cyclic GMP.
Topics: Animals; Animals, Newborn; Arginine; Bradykinin; Concanavalin A; Cyclic GMP; Indazoles; Methylene Blue; Nitric Oxide; Nitroprusside; Nociceptors; Rats; Receptors, Bradykinin; Spinal Cord | 1994 |
Neural nitric oxide mediates Edinger-Westphal nucleus evoked increase in choroidal blood flow in the pigeon.
Topics: Animals; Arginine; Blood Pressure; Choroid; Columbidae; Electric Stimulation; Enzyme Inhibitors; Ganglia, Parasympathetic; Indazoles; Laser-Doppler Flowmetry; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oculomotor Nerve; Regional Blood Flow | 1996 |
The selective neuronal NO synthase inhibitor 7-nitro-indazole blocks both long-term potentiation and depotentiation of field EPSPs in rat hippocampal CA1 in vivo.
Topics: Animals; Arginine; Electrophysiology; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hippocampus; Indazoles; Long-Term Potentiation; Male; Membrane Potentials; Nitric Oxide Synthase; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Urethane | 1996 |
Reduction of quinonoid dihydrobiopterin to tetrahydrobiopterin by nitric oxide synthase.
Topics: Animals; Arginine; Biopterins; Cell Line; Cerebellum; Enzyme Inhibitors; Humans; Indazoles; Kidney; Kinetics; Methotrexate; NADP; Nitric Oxide Synthase; Nitroarginine; Onium Compounds; Oxidation-Reduction; Rats; Recombinant Proteins; Transfection | 1996 |
Nitric oxide inhibits rat intestinal secretion by Clostridium difficile toxin A but not Vibrio cholerae enterotoxin.
Topics: Acetylcysteine; Animals; Arginine; Bacterial Toxins; Cell Degranulation; Chymases; Clostridioides difficile; Enterotoxins; Enzyme Inhibitors; Guanidines; Ileum; Indazoles; Intestinal Mucosa; Male; Mast Cells; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Permeability; Peroxidase; Rats; Rats, Wistar; Serine Endopeptidases; Vibrio cholerae | 1996 |
Reduction of the neurological deficit in mice with traumatic brain injury by nitric oxide synthase inhibitors.
Topics: Analysis of Variance; Animals; Arginine; Brain Injuries; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Inhibitors; Indazoles; Male; Mice; Motor Activity; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Time Factors | 1996 |
7-nitroindazole: an inhibitor of nitric oxide synthase.
Topics: Analgesics; Animals; Aorta; Arginine; Carbachol; Cattle; Cerebellum; Endothelium, Vascular; Enzyme Inhibitors; Female; Indazoles; Isoenzymes; Lung; Male; Mice; Molecular Structure; N-Methylaspartate; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitro Compounds; Rabbits; Radioisotope Dilution Technique; Rats; Sensitivity and Specificity; Structure-Activity Relationship; Tritium | 1996 |
Evidence from its cardiovascular effects that 7-nitroindazole may inhibit endothelial nitric oxide synthase in vivo.
Topics: Acetylcholine; Animals; Arginine; Blood Pressure; Endothelium, Vascular; Enzyme Inhibitors; Heart Rate; Indazoles; Male; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 1996 |
Macula densa derived nitric oxide in regulation of glomerular capillary pressure.
Topics: Animals; Arginine; Capillary Resistance; Enzyme Inhibitors; Guanidines; Indazoles; Juxtaglomerular Apparatus; Kidney Glomerulus; Kidney Tubules, Proximal; Male; Methylguanidine; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Pressure; Rats; Rats, Sprague-Dawley; Time Factors; Vasoconstriction | 1996 |
Reduction of the neurological deficit in mice with traumatic brain injury by nitric oxide synthase inhibitors.
Topics: Analysis of Variance; Animals; Arginine; Brain Injuries; Enzyme Inhibitors; Indazoles; Male; Mice; Neurologic Examination; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Time Factors | 1996 |
Anticonvulsant effects of 7-nitroindazole in rodents with reflex epilepsy may result from L-arginine accumulation or a reduction in nitric oxide or L-citrulline formation.
Topics: Animals; Anticonvulsants; Arginine; Blood Pressure; Citrulline; Disease Models, Animal; Epilepsy; Female; Heart Rate; Indazoles; Male; Mice; Mice, Inbred DBA; Motor Activity; Nitric Oxide; Nitric Oxide Synthase; Noise; Rats; Rats, Inbred Strains; Reflex; Seizures | 1996 |
Amplification of spinal nociceptive transmission depends on the generation of nitric oxide in normal and carrageenan rats.
Topics: Animals; Arginine; Blood Pressure; Carrageenan; Dose-Response Relationship, Drug; Enzyme Inhibitors; Evoked Potentials; Excipients; Indazoles; Injections, Intravenous; Injections, Spinal; Male; Neuritis; Neurons; Nitric Oxide; Nociceptors; Rats; Rats, Sprague-Dawley; Spinal Cord; Synaptic Transmission; Transcutaneous Electric Nerve Stimulation | 1996 |
Endogenous protection against reperfusion-induced ventricular fibrillation: role of neuronal versus non-neuronal sources of nitric oxide and species dependence in the rat versus rabbit isolated heart.
Topics: Animals; Arginine; Blood Flow Velocity; Enzyme Inhibitors; Heart Rate; In Vitro Techniques; Indazoles; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rabbits; Rats; Rats, Wistar; Species Specificity; Ventricular Fibrillation | 1996 |
Neuronal nitric oxide reduces sympathetic excitability by modulation of central glutamate effects in pigs.
Topics: Animals; Arginine; Brain Stem; Citrulline; Enzyme Inhibitors; Glutamic Acid; Heart Rate; Hemodynamics; Indazoles; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Swine; Sympathetic Nervous System; Thiourea; Vagotomy | 1997 |
Monitoring nitric oxide (NO) in rat locus coeruleus: differential effects of NO synthase inhibitors.
Topics: Anilides; Animals; Arginine; Drug Evaluation, Preclinical; Electrochemistry; Enzyme Inhibitors; Indazoles; Locus Coeruleus; Male; Monitoring, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 1997 |
Effects of modulation of nitric oxide on acoustic startle responding and prepulse inhibition in rats.
Topics: Acoustic Stimulation; Animals; Arginine; Excitatory Amino Acid Antagonists; Indazoles; Male; Neural Inhibition; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Phencyclidine; Rats; Rats, Sprague-Dawley; Reflex, Startle | 1997 |
Influence of 7-nitroindazole on the anticonvulsive action of conventional antiepileptic drugs.
Topics: Animals; Anticonvulsants; Arginine; Avoidance Learning; Blood Pressure; Electroshock; Enzyme Inhibitors; Female; GABA Modulators; Indazoles; Memory; Mice; Movement; Nitric Oxide Synthase; Phenobarbital; Receptors, Muscarinic | 1997 |
Nitric oxide-synthesizing perivascular nerves in the rat middle cerebral artery.
Topics: Animals; Arginine; Cerebral Arteries; Electric Stimulation; Enzyme Inhibitors; In Vitro Techniques; Indazoles; Male; Nervous System; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred Strains; Vasodilation | 1997 |
Nitric oxide synthase inhibition attenuates signs of ethanol withdrawal in rats.
Topics: Acoustic Stimulation; Alcoholism; Animals; Arginine; Behavior, Animal; Enzyme Inhibitors; Ethanol; Indazoles; Male; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Seizures; Substance Withdrawal Syndrome | 1997 |
Nitric oxide signalling is required for the generation of anoxia-induced long-term potentiation in the hippocampus.
Topics: Animals; Arginine; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Hippocampus; Hypoxia; In Vitro Techniques; Indazoles; Long-Term Potentiation; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Sprague-Dawley; Reaction Time; Signal Transduction; Synaptic Transmission | 1997 |
The effect of 7-nitro indazole on pentobarbital-induced sleep in mice.
Topics: Animals; Arginine; Enzyme Inhibitors; Hypnotics and Sedatives; Indazoles; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Synthase; Pentobarbital; Sleep | 1997 |
Neuronal NOS-cGMP-dependent ACh-induced relaxation in pial arterioles of endothelial NOS knockout mice.
Topics: Acetylcholine; Animals; Arginine; Arterioles; Autoradiography; Brain; Citrulline; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Indazoles; Mice; Mice, Knockout; Neurons; Nitric Oxide Synthase; Pia Mater; Quinuclidinyl Benzilate; Receptors, Muscarinic; Vasodilation | 1998 |
Characterization of Cyprinus carpio brain nitric oxide synthase.
Topics: Animals; Arginine; Brain; Brain Chemistry; Carps; Citrulline; Enzyme Inhibitors; Free Radicals; Indazoles; Male; Nitric Oxide Synthase; Rats; Rats, Wistar; Species Specificity; Tritium | 1998 |
L-arginine-NO pathway and CNS oxygen toxicity.
Topics: Animals; Arginine; Central Nervous System; Electroencephalography; Enzyme Inhibitors; Hyperoxia; Indazoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxygen; Penicillamine; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Seizures | 1998 |
Nitroarginine and tetrahydrobiopterin binding to the haem domain of neuronal nitric oxide synthase using a scintillation proximity assay.
Topics: Animals; Arginine; Binding Sites; Binding, Competitive; Biopterins; Enzyme Inhibitors; Heme; Indazoles; Isothiuronium; Kinetics; Nitric Oxide Synthase; Nitroarginine; Oxidoreductases; Oxygenases; Peptide Fragments; Protein Binding; Rats; Recombinant Fusion Proteins | 1998 |
L-arginine produces NO-independent increases in dopamine efflux in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Arginine; Citrulline; Corpus Striatum; Dopamine; Enzyme Inhibitors; Homovanillic Acid; Indazoles; Male; Microdialysis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Stereoisomerism | 1998 |
Beta-amyloid induced reduction in synaptic transmission is reversed by inhibitors of nitric oxide synthase.
Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; Arginine; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Free Radicals; Indazoles; Male; Nitric Oxide Synthase; Polymethacrylic Acids; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 1998 |
Nitric oxide synthase inhibitors alter ventilation in isoflurane anesthetized rats.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Arginine; Carbon Dioxide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hemodynamics; Indazoles; Isoflurane; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Respiration | 1998 |
Multiple nitric oxide sources in neurogenic plasma extravasation in rat hindpaw skin.
Topics: Animals; Arginine; Capillary Permeability; Capsaicin; Coloring Agents; Enzyme Inhibitors; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Hindlimb; Indazoles; Male; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Skin | 1998 |
Effect of nitric oxide synthase inhibition on the sympatho-vagal contol of heart rate.
Topics: Adrenergic Fibers; Animals; Arginine; Enzyme Inhibitors; Guinea Pigs; Heart Atria; Heart Rate; Indazoles; Isoproterenol; Male; Neural Inhibition; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Polymethacrylic Acids; Propranolol; Rabbits; Sympatholytics; Sympathomimetics; Vagus Nerve | 1998 |
Nitric oxide facilitates N-methyl-D-aspartate-induced burst firing in dopamine neurons from rat midbrain slices.
Topics: Animals; Apamin; Arginine; Dopamine; Drug Synergism; Electrophysiology; Enzyme Inhibitors; In Vitro Techniques; Indazoles; Male; Mesencephalon; N-Methylaspartate; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroarginine; Rats; Rats, Sprague-Dawley | 1998 |
Dual role for nitric oxide in dynorphin spinal neurotoxicity.
Topics: Animals; Arginine; Dose-Response Relationship, Drug; Dynorphins; Enzyme Inhibitors; Guanidines; Immunohistochemistry; Indazoles; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitrogen Oxides; Rats; Rats, Wistar; Spermine; Spinal Cord; Time Factors | 1999 |
A neuronal nitric oxide synthase inhibitor 7-nitroindazole reduces the 5-HT1A receptor against 8-OH-DPAT-elicited hyperphagia in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Arginine; Autoreceptors; Enzyme Inhibitors; Feeding Behavior; Hyperalgesia; Hypothalamus; Indazoles; Male; Neurons; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Receptor Agonists | 1999 |
7-Nitroindazole, a selective inhibitor of nNOS, increases hippocampal extracellular glutamate concentration in status epilepticus induced by kainic acid in rats.
Topics: Animals; Arginine; Chromatography, High Pressure Liquid; Citrulline; Electroencephalography; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Extracellular Space; Glutamic Acid; Hippocampus; Indazoles; Kainic Acid; Male; Microdialysis; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; Status Epilepticus; Synaptic Transmission | 1999 |
Inhibition of nitric oxide synthase reduces ultrasonic vocalizations of rat pups.
Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Arginine; Body Temperature; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indazoles; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Long-Evans; Stereoisomerism; Ultrasonics; Vocalization, Animal | 1999 |
Nitric oxide signaling pathway mediates the L-arginine-induced cardiovascular effects in the nucleus tractus solitarii of rats.
Topics: Aminoquinolines; Animals; Arginine; Blood Pressure; Calcium; Calmodulin; Cardiovascular System; Cyclic GMP-Dependent Protein Kinases; Guanylate Cyclase; Heart Rate; Indazoles; Isoquinolines; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; Solitary Nucleus; Solubility; Sulfonamides | 1999 |
Nitric oxide as a modulator of central respiratory rhythm in the isolated brainstem of the bullfrog (Rana catesbeiana).
Topics: Animals; Arginine; Brain Stem; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Indazoles; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Oxygen Consumption; Perfusion; Rana catesbeiana; Respiratory Mechanics | 1999 |
Anxiolytic-like effects of 7-nitroindazole in the rat plus-maze test.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Arginine; Exploratory Behavior; Indazoles; Male; Motor Activity; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Wistar | 2000 |
Suppression of paraquat-induced wet dog shakes by nitric oxide synthase inhibitors in rats.
Topics: Animals; Arginine; Enzyme Inhibitors; Herbicides; Indazoles; Male; Naloxone; Narcotic Antagonists; Nitric Oxide Synthase; Nitroarginine; Paraquat; Rats; Rats, Sprague-Dawley; Reflex | 2000 |
7-Nitroindazole potentiates the antiseizure activity of some anticonvulsants in DBA/2 mice.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Arginine; Body Temperature; Brain; Brain Chemistry; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Indazoles; Male; Mice; Mice, Inbred DBA; Monoamine Oxidase; Motor Activity; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Norepinephrine | 2000 |
Transient changes in the synthesis of nitric oxide result in long-term as well as short-term changes in acetic acid-induced writhing in mice.
Topics: Acetic Acid; Animals; Arginine; Behavior, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hot Temperature; Indazoles; Injections, Spinal; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pain Measurement; Reaction Time; Spinal Cord | 2000 |
Antidepressant-like effect of 7-nitroindazole in the forced swimming test in rats.
Topics: Animals; Antidepressive Agents; Arginine; Dose-Response Relationship, Drug; Immobilization; Indazoles; Male; Motor Activity; Rats; Rats, Wistar; Swimming; Time Factors | 2000 |
Endogenous nitric oxide decreases hippocampal levels of serotonin and dopamine in vivo.
Topics: Animals; Arginine; Dopamine; Enzyme Inhibitors; Extracellular Space; Hippocampus; Indazoles; Male; Methylene Blue; Microdialysis; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Serotonin | 2000 |
NMDA antagonists block expression of sensitization of amphetamine- and apomorphine-induced stereotypy.
Topics: Amphetamine; Animals; Apomorphine; Arginine; Behavior, Animal; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Indazoles; Male; Mice; Nitric Oxide Synthase; Piperazines; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior | 2000 |
Nitric oxide modulates lithium-induced conditioned taste aversion.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Arginine; Avoidance Learning; Enzyme Inhibitors; Fenclonine; Indazoles; Lithium; Male; Methylene Blue; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Saccharin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sweetening Agents; Taste | 2001 |
Neuronal nitric oxide strongly suppresses sympathetic outflow in high-salt Dahl rats.
Topics: Animals; Arginine; Blood Pressure; Diet; Enzyme Inhibitors; Heart Rate; Indazoles; Male; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Inbred Dahl; Rest; Sodium Chloride; Sympathetic Nervous System | 2001 |
Evidence for a K(ATP) ion channel link in the inhibition of hypercapnic dilation of pial arterioles by 7-nitroindazole and tetrodotoxin.
Topics: Animals; Arginine; Arterioles; Carbon Dioxide; Cromakalim; Hypercapnia; Indazoles; Ion Channel Gating; Lysine; Male; Nitric Oxide Synthase; Nitroprusside; Pinacidil; Potassium Channels; Rats; Rats, Sprague-Dawley; Respiration; Telencephalon; Tetrodotoxin; Vasodilation; Vasodilator Agents | 2001 |
Inhibition of neuronal nitric oxide synthase by 7-methoxyindazole and related substituted indazoles.
Topics: Analgesics; Animals; Arginine; Cerebellum; Dose-Response Relationship, Drug; Electrons; Enzyme Inhibitors; Indazoles; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pain Measurement; Rats; Structure-Activity Relationship | 2001 |
Nitric oxide regulation of lingual blood flow in the rat.
Topics: Animals; Arginine; Blood Pressure; Enzyme Inhibitors; Heart Rate; Indazoles; Kinetics; Laser-Doppler Flowmetry; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Stereoisomerism; Tongue | 2001 |
Relatively selective neuronal nitric oxide synthase inhibition by 7-nitroindazole in monkey isolated cerebral arteries.
Topics: Animals; Arginine; Cerebral Arteries; Dose-Response Relationship, Drug; Electric Stimulation; Endothelium, Vascular; Enzyme Inhibitors; Histamine; In Vitro Techniques; Indazoles; Macaca; Nicotine; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Vasoconstriction; Vasodilation | 2001 |
Protective effect of 7-nitroindazole against DSP-4 induced noradrenaline depletion in mouse hippocampus.
Topics: Animals; Arginine; Benzylamines; Enzyme Inhibitors; Hippocampus; Indazoles; Male; Mice; Mice, Inbred Strains; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Norepinephrine; Sympathomimetics | 2001 |
Delayed induction of alpha B-crystallin in activated glia cells of hippocampus in kainic acid-treated mouse brain.
Topics: Animals; Arginine; Astrocytes; Crystallins; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Gliosis; Heat-Shock Proteins; Hippocampus; Immunohistochemistry; Indazoles; Kainic Acid; Male; Mice; Mice, Inbred BALB C; Molecular Chaperones; Neoplasm Proteins; Nerve Degeneration; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Seizures | 2001 |
Neuronal nitric oxide synthase (NOS) regulates leukocyte-endothelial cell interactions in endothelial NOS deficient mice.
Topics: Animals; Arginine; Cell Adhesion; Cell Communication; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Genotype; Hemodynamics; Hydrogen Peroxide; Indazoles; Intestinal Mucosa; Leukocytes; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidants; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Venules | 2001 |
Nitric oxide- and oxygen-derived free radical generation from control and lipopolysaccharide-treated rat polymorphonuclear leukocyte.
Topics: Animals; Antioxidants; Arachidonic Acid; Arginine; Biological Transport; Catalase; Enzyme Inhibitors; Flow Cytometry; Free Radicals; Guanidines; Indazoles; Lipopolysaccharides; Male; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxygen; Peroxidase; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2001 |
Nitric oxide modulates sympathoexcitatory cardiac-cardiovascular reflexes elicited by bradykinin.
Topics: Animals; Arginine; Baroreflex; Blood Pressure; Bradykinin; Cats; Denervation; Enzyme Inhibitors; Female; Heart Rate; Indazoles; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; omega-N-Methylarginine; Sympathetic Nervous System; Vagotomy | 2001 |
NO mediates ginsenoside Rg1-induced long-term potentiation in anesthetized rats.
Topics: Anesthesia; Animals; Arginine; Dentate Gyrus; Drug Interactions; Enzyme Inhibitors; Ginsenosides; Hippocampus; Indazoles; Long-Term Potentiation; Male; Nitric Oxide; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 2001 |
Effects of intracerebroventricular administration of 7-nitroindazole on tolerance to ethanol.
Topics: Animals; Arginine; Ataxia; Drug Tolerance; Enzyme Inhibitors; Ethanol; Hypothermia; Indazoles; Injections, Intraventricular; Male; Nerve Tissue Proteins; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Stereoisomerism | 2002 |
Comparison of nitric oxide donors in lowering intraocular pressure in rabbits: role of cyclic GMP.
Topics: Animals; Arginine; Cyclic GMP; Female; Indazoles; Intraocular Pressure; Male; Nitric Oxide Donors; Nitric Oxide Synthase; Purinones; Rabbits | 2002 |
Endothelial nitric oxide modulates perivascular sensory neurotransmission in the rat isolated mesenteric arterial bed.
Topics: Animals; Arginine; Bucladesine; Calcitonin Gene-Related Peptide; Capsaicin; Cyclic GMP; Electric Stimulation; Endothelium, Vascular; In Vitro Techniques; Indazoles; Male; Mesenteric Arteries; Neurons, Afferent; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroprusside; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents | 2002 |
Reduction of cGMP and nitric oxide has antidepressant-like effects in the forced swimming test in rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Arginine; Cyclic GMP; Depression; Dimethyl Sulfoxide; Enzyme Inhibitors; Guanylate Cyclase; Imipramine; Indazoles; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Swimming | 2002 |
Therapeutic effect of neuronal nitric oxide synthase inhibitor (7-nitroindazole) against MPTP neurotoxicity in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Arginine; Brain Chemistry; Dopamine; Dopamine Agents; Enzyme Inhibitors; Glial Fibrillary Acidic Protein; Immunohistochemistry; Indazoles; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase Inhibitors; Neostriatum; Neurotoxicity Syndromes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pargyline; Tyrosine 3-Monooxygenase | 2002 |
Mechanism of nicotine-evoked release of 3H-noradrenaline in human cerebral cortex slices.
Topics: Adolescent; Adult; Arginine; Calcium; Calcium Channel Blockers; Cerebral Cortex; Dihydro-beta-Erythroidine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluoxetine; Ganglionic Stimulants; Guanylate Cyclase; Humans; In Vitro Techniques; Indazoles; Male; Mecamylamine; Methylene Blue; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nicotine; Nicotinic Antagonists; Nitrendipine; Nitric Oxide Synthase; Norepinephrine; omega-Conotoxin GVIA; Oxadiazoles; Purinones; Quinoxalines; Tetrodotoxin; Tritium; Tubocurarine | 2002 |
Modulation of stress-induced neurobehavioral changes by nitric oxide in rats.
Topics: Animals; Arginine; Behavior, Animal; Brain; Diazepam; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indazoles; Male; Maze Learning; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Psychomotor Performance; Rats; Rats, Wistar; Restraint, Physical | 2003 |
Nitric oxide mediates metabolism as well as respiratory and cardiac responses to hypoxia in the snail lymnaea stagnalis.
Topics: Animals; Arginine; Heart Rate; Hypoxia; Indazoles; Lymnaea; Nitric Oxide; Nitric Oxide Synthase; Oxygen Consumption; Respiration; Time Factors | 2003 |
Novel thrombin inhibitors incorporating non-basic partially saturated heterobicyclic P1-arginine mimetics.
Topics: Arginine; Binding Sites; Biomimetic Materials; Cinoxacin; Drug Design; Enzyme Inhibitors; Heterocyclic Compounds, 2-Ring; Humans; Hydrogen-Ion Concentration; Indazoles; Indoles; Models, Molecular; Structure-Activity Relationship; Substrate Specificity; Thrombin; Trypsin | 2003 |
Antidepressant- and anxiolytic-like effects of selective neuronal NOS inhibitor 1-(2-trifluoromethylphenyl)-imidazole in mice.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety; Arginine; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exploratory Behavior; Imidazoles; Imipramine; Immobilization; Indazoles; Male; Mice; Mice, Inbred C57BL; Motor Activity; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Reaction Time; Swimming | 2003 |
The effect of L-arginine on slow motility of mammalian outer hair cell.
Topics: Animals; Arginine; Calcium; Cell Membrane Permeability; Cell Movement; Cell Size; Cyclic GMP; Enzyme Inhibitors; Extracellular Fluid; Guinea Pigs; Hair Cells, Auditory, Outer; Indazoles; Intracellular Membranes; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Osmolar Concentration | 2003 |
Cyanide binding study of neuronal nitric oxide synthase: effects of inhibitors and mutations at the substrate binding site.
Topics: Arginine; Binding Sites; Citrulline; Cyanides; Enzyme Inhibitors; Indazoles; Mutagenesis, Site-Directed; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Spectrophotometry, Ultraviolet; Thiourea | 2003 |
Behavioral effects of NMDA receptor agonists and antagonists in combination with nitric oxide-related compounds.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Conditioning, Operant; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Gallic Acid; Guanidines; Indazoles; Injections, Intraperitoneal; Kynurenic Acid; Molsidomine; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroprusside; Phencyclidine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2003 |
Cardiac enkephalins attenuate vagal bradycardia: interactions with NOS-1-cGMP systems in canine sinoatrial node.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Bradycardia; Cyclic GMP; Dogs; Dose-Response Relationship, Drug; Enkephalin, Methionine; Enzyme Inhibitors; Indazoles; Methacholine Chloride; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Parasympathomimetics; Penicillamine; Phosphodiesterase Inhibitors; Sinoatrial Node; Vagus Nerve | 2003 |
Neuronal nitric oxide synthase: its role and regulation in macula densa cells.
Topics: Angiotensin II; Animals; Arginine; Biological Transport; Enzyme Inhibitors; Indazoles; Juxtaglomerular Apparatus; Loop of Henle; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rabbits; Sodium Chloride; Sodium-Potassium-Chloride Symporters; Vasoconstrictor Agents | 2003 |
[Nitric oxide is involved in the modulation of central respiratory rhythm].
Topics: Animals; Animals, Newborn; Arginine; Brain Stem; Electrophysiology; Indazoles; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Random Allocation; Rats; Rats, Sprague-Dawley; Respiration; Respiratory Center | 2003 |
NOS inhibitors exhibit antinociceptive properties in the rat formalin test.
Topics: Analgesics; Animals; Arginine; Blood Pressure; Enzyme Inhibitors; Formaldehyde; Guanidines; Heart Rate; Indazoles; Nitric Oxide Synthase; Nitroarginine; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Sodium Chloride; Time Factors | 2003 |
Inhibitory effects and spectral interactions of isomeric methoxyindazoles on recombinant nitric oxide synthases.
Topics: Arginine; Citrulline; Cytochromes c; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Indazoles; Isoenzymes; NADP; Nitric Oxide Synthase; Recombinant Proteins; Spectrophotometry, Ultraviolet | 2003 |
Effect of L-arginine on restraint stress induced modulation of immune responses in rats and mice.
Topics: Animals; Antibody Formation; Arginine; Cell Migration Inhibition; Dose-Response Relationship, Immunologic; Drug Administration Schedule; Erythrocytes; Hypersensitivity, Delayed; Immunity, Cellular; Indazoles; Injections, Intraperitoneal; Male; Mice; Nerve Tissue Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; Restraint, Physical; Sheep; Stress, Physiological; Time Factors | 2004 |
Changes in the dimeric state of neuronal nitric oxide synthase affect the kinetics of secretagogue-induced insulin response.
Topics: Animals; Arginine; Carrier Proteins; Cell Line; Dimerization; Drosophila Proteins; Dyneins; Enzyme Inhibitors; Glucose; Indazoles; Insulin; Insulin Secretion; Kinetics; Male; Miconazole; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroarginine; Nitroprusside; Rats; Rats, Wistar; Surface Plasmon Resonance | 2004 |
Pharmacological and biochemical studies on the possible role of nitric oxide in stress adaptation in rats.
Topics: Adaptation, Physiological; Animals; Arginine; Brain Chemistry; Drug Evaluation, Preclinical; Indazoles; India; Male; Maze Learning; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Restraint, Physical; Stress, Physiological | 2004 |
Independent modification of baroreceptor and exercise pressor reflex function by nitric oxide in nucleus tractus solitarius.
Topics: Animals; Arginine; Autonomic Nervous System; Baroreflex; Cats; Diffusion; Enzyme Inhibitors; Female; Indazoles; Male; Microdialysis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Physical Exertion; Solitary Nucleus | 2005 |
Nitric oxide synthase inhibitors and nitric oxide donors modulate the biosynthesis of thaxtomin A, a nitrated phytotoxin produced by Streptomyces spp.
Topics: Arginine; Enzyme Inhibitors; Free Radical Scavengers; Guanidines; Indazoles; Indoles; Molecular Structure; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Piperazines; Streptomyces | 2005 |
Release of arginine, glutamate and glutamine in the hippocampus of freely moving rats: Involvement of nitric oxide.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Behavior, Animal; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; Glutamine; Hippocampus; Indazoles; Male; Microdialysis; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Penicillamine; Quinoxalines; Rats; Rats, Wistar; Wakefulness | 2005 |
Functional characterization of brain mitochondrial nitric oxide synthase during hypertension and aging.
Topics: Aging; Animals; Arginine; Brain; Citrulline; Hypertension; Indazoles; Male; Mitochondria; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxygen Consumption; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar | 2006 |
Anxiolytic-like effects induced by nitric oxide synthase inhibitors microinjected into the medial amygdala of rats.
Topics: Amygdala; Animals; Anti-Anxiety Agents; Anxiety; Arginine; Darkness; Enzyme Inhibitors; Indazoles; Light; Male; Microinjections; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Periaqueductal Gray; Rats; Rats, Wistar | 2006 |
Involvement of nitric oxide pathway in the acute anticonvulsant effect of melatonin in mice.
Topics: Animals; Anticonvulsants; Arginine; Convulsants; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Inhibitors; Guanidines; Indazoles; Injections, Intraperitoneal; Kindling, Neurologic; Male; Melatonin; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroarginine; Pentylenetetrazole; Seizures | 2006 |
Striatal microinjections of nitric oxide synthase inhibitors and L-arginine fail to exert effects on paroxysmal dystonia in the dtsz mutant.
Topics: Animals; Arginine; Corpus Striatum; Cricetinae; Dystonia; Indazoles; Microinjections; Motor Activity; Mutation; Nitric Oxide; Nitric Oxide Synthase Type I | 2006 |
Inhibition of neuronal nitric oxide synthase reduces isoflurane MAC and motor activity even in nNOS knockout mice.
Topics: Anesthetics, Inhalation; Animals; Arginine; Enzyme Inhibitors; Female; Indazoles; Isoflurane; Male; Mice; Mice, Knockout; Motor Activity; Nitric Oxide Synthase Type I | 2006 |
Inhibition of neuronal nitric oxide synthase in the rat hippocampus induces antidepressant-like effects.
Topics: Animals; Antidepressive Agents; Arginine; Dose-Response Relationship, Drug; Hippocampus; Imipramine; Indazoles; Male; Molsidomine; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Rats; Rats, Wistar | 2006 |
Involvement of nitric oxide-soluble guanylyl cyclase pathway in the control of maximal dentate gyrus activation in the rat.
Topics: Animals; Arginine; Dentate Gyrus; Electrophysiology; Enzyme Inhibitors; Guanylate Cyclase; Indazoles; Iontophoresis; Male; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase Type III; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase | 2006 |
Acute and conditioned hypoxic tolerance augmented by endothelial nitric oxide synthase inhibition in mice.
Topics: Acute Disease; Animals; Arginine; Endothelium, Vascular; Enzyme Inhibitors; Hypoxia; Imines; Indazoles; Male; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroarginine; Time Factors | 2007 |
The role of nitric oxide on the convulsive behavior and oxidative stress induced by methylmalonate: an electroencephalographic and neurochemical study.
Topics: Animals; Anticonvulsants; Arginine; Corpus Striatum; Dose-Response Relationship, Drug; Electroencephalography; Indazoles; Male; Methylmalonic Acid; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Premedication; Rats; Rats, Wistar; Seizures; Sodium-Potassium-Exchanging ATPase | 2007 |
Does nitric oxide modulate transmitter release at the mammalian neuromuscular junction?
Topics: Animals; Arginine; Cyclic GMP; Diaphragm; Drug Synergism; Electric Stimulation; Enzyme Activators; Exocytosis; Guanylate Cyclase; Indazoles; Intracellular Fluid; Motor Endplate; Neuromuscular Junction; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Phrenic Nerve; Purinergic P1 Receptor Antagonists; Quinoxalines; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Sodium Nitrite; Xanthines | 2007 |
Resting tension affects eNOS activity in a calcium-dependent way in airways.
Topics: Acetylcholine; Animals; Arginine; Calcium; Dose-Response Relationship, Drug; Drug Interactions; Female; Genistein; Hydroquinones; In Vitro Techniques; Indazoles; Male; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rabbits; Trachea | 2007 |
Soluble amyloid beta1-42 reduces dopamine levels in rat prefrontal cortex: relationship to nitric oxide.
Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; Arginine; Dopamine; Drug Interactions; Enzyme Inhibitors; Indazoles; Male; Microdialysis; Nitric Oxide; Peptide Fragments; Prefrontal Cortex; Rats; Rats, Wistar; Time Factors | 2007 |
Possible involvement of L-arginine-nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) signaling pathway in the antidepressant activity of berberine chloride.
Topics: Animals; Antidepressive Agents; Arginine; Behavior, Animal; Berberine; Brain Chemistry; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Hindlimb Suspension; Indazoles; Injections, Intraperitoneal; Male; Mice; Motor Activity; Neurotransmitter Agents; Nitric Oxide; Piperazines; Purines; Signal Transduction; Sildenafil Citrate; Stress, Psychological; Sulfones; Swimming; Time Factors | 2007 |
Intracerebroventricular administration of nitric oxide-sensitive guanylyl cyclase inhibitors induces catalepsy in mice.
Topics: Animals; Arginine; Behavior, Animal; Catalepsy; Corpus Striatum; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Indazoles; Injections, Intraventricular; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Time Factors | 2007 |
7-Nitroindazole, a neuronal nitric oxide synthase inhibitor, impairs passive-avoidance and elevated plus-maze memory performance in rats.
Topics: Animals; Anxiety; Arginine; Avoidance Learning; Blood Glucose; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Indazoles; Male; Memory; Nitric Oxide Synthase Type I; Psychomotor Performance; Rats; Rats, Wistar | 2007 |
Modulatory effects of nitric oxide-active drugs on the anticonvulsant activity of lamotrigine in an experimental model of partial complex epilepsy in the rat.
Topics: Animals; Anticonvulsants; Arginine; Brain; Dentate Gyrus; Disease Models, Animal; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Epilepsy, Complex Partial; Indazoles; Lamotrigine; Male; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Triazines | 2007 |
The role of nitric oxide in the anticonvulsant effects of pyridoxine on penicillin-induced epileptiform activity in rats.
Topics: Analysis of Variance; Animals; Anticonvulsants; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; Enzyme Inhibitors; Epilepsy; Indazoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Penicillins; Pyridoxine; Rats; Rats, Wistar; Somatosensory Cortex; Time Factors | 2007 |
Nitric oxide-mediated anxiolytic-like and antidepressant-like effects in animal models of anxiety and depression.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Arginine; Depression; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indazoles; Male; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Raphe Nuclei; Rats; Rats, Wistar; Swimming; Synaptic Transmission | 2008 |
Lamotrigine differently modulates 7-nitroindazole and L-arginine influence on rat maximal dentate gyrus activation.
Topics: Animals; Anticonvulsants; Arginine; Dentate Gyrus; Electric Stimulation; Enzyme Inhibitors; Indazoles; Lamotrigine; Male; Nitric Oxide; Rats; Rats, Wistar; Seizures; Triazines | 2008 |
Role of nitric oxide deficiency in the development of hypertension in hydronephrotic animals.
Topics: Animals; Arginine; Blood Pressure; Disease Models, Animal; Diuresis; Enzyme Inhibitors; Hydronephrosis; Hypertension; Indazoles; Kidney; Kidney Cortex; Kidney Tubules, Proximal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Potassium; Rats; Rats, Sprague-Dawley; Sodium; Sodium Chloride, Dietary; Ureteral Obstruction | 2008 |
[L-arginine pretreatment lowers cerebral metabolism for cerebral protection during deep hypothermic circulatory arrest].
Topics: Animals; Arginine; Brain; Brain Ischemia; Circulatory Arrest, Deep Hypothermia Induced; Dogs; Female; Indazoles; Male | 2008 |
Inhibition of neuronal nitric oxide synthase prevents iron-induced cerebellar Purkinje cell loss in the rat.
Topics: Animals; Arginine; Cell Death; Cerebellum; Drug Interactions; Enzyme Inhibitors; Indazoles; Iron; Male; Neural Inhibition; Nitric Oxide Synthase Type I; Purkinje Cells; Rats; Rats, Wistar; Trace Elements | 2008 |
Nitric oxide signaling pathway in the anti-convulsant effect of adenosine against pentylenetetrazol-induced seizure threshold in mice.
Topics: Adenosine; Animals; Anticonvulsants; Arginine; Convulsants; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Enzyme Inhibitors; Guanidines; Indazoles; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitroprusside; Pentylenetetrazole; Phosphodiesterase 5 Inhibitors; Phosphodiesterase Inhibitors; Piperazines; Purines; Seizures; Signal Transduction; Sildenafil Citrate; Sulfones | 2008 |
Effect of inhibition of neuronal nitric oxide synthase and L-arginine supplementation on renal ischaemia-reperfusion injury and the renal nitric oxide system.
Topics: Animals; Arginine; Gene Expression Regulation, Enzymologic; Indazoles; Isoenzymes; Kidney; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Messenger; Substrate Specificity; Up-Regulation | 2008 |
Nitric oxide modulates the frog heart ventricle morphodynamics.
Topics: Animals; Anura; Arginine; Cyclic GMP; Female; Heart Ventricles; In Vitro Techniques; Indazoles; Male; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Perfusion; Serine; Software; Ventricular Function | 2008 |
Participation of the GABA/benzodiazepine receptor and the NO-cyclicGMP pathway in the "antinociceptive-like effects" of diazepam.
Topics: Analgesics; Animals; Arginine; Cyclic GMP; Diazepam; Enzyme Inhibitors; Guanylate Cyclase; Hypnotics and Sedatives; Indazoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Pain Measurement; Rats; Rats, Wistar; Receptors, GABA-A; Signal Transduction | 2008 |
Nitric oxide and glutamate in the dorsal facial area regulate common carotid blood flow in the cat.
Topics: Animals; Arginine; Carotid Artery, Common; Cats; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Facial Nerve; Female; Glutamic Acid; Guanylate Cyclase; Indazoles; Male; Methylene Blue; Microdialysis; Microinjections; Nerve Fibers; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Regional Blood Flow; S-Nitroso-N-Acetylpenicillamine | 2008 |
Antidepressant-like effect of folic acid: Involvement of NMDA receptors and L-arginine-nitric oxide-cyclic guanosine monophosphate pathway.
Topics: Animals; Antidepressive Agents; Arginine; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Folic Acid; Indazoles; Injections, Intraventricular; Male; Methylene Blue; Mice; N-Methylaspartate; Nitric Oxide; Nitric Oxide Donors; Receptors, N-Methyl-D-Aspartate; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Swimming; Vitamin B Complex | 2008 |
Effect of nitric oxide/cyclic guanosine mono-phosphate pathway on gallbladder relaxant response in bile duct-ligated guinea pigs.
Topics: Amrinone; Animals; Arginine; Bile Ducts; Cyclic GMP; Gallbladder; Guanidines; Guinea Pigs; Hydrazines; In Vitro Techniques; Indazoles; Ligation; Male; Muscle Relaxation; Nitric Oxide; Nitric Oxide Donors; Papaverine; Piperazines; Purines; Sildenafil Citrate; Sulfones | 2009 |
In the rat maximal dentate activation model of partial complex epilepsy, the anticonvulsant activity of levetiracetam is modulated by nitric oxide-active drugs.
Topics: Animals; Anticonvulsants; Arginine; Dentate Gyrus; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Enzyme Inhibitors; Epilepsy, Complex Partial; Indazoles; Levetiracetam; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Piracetam; Rats; Rats, Wistar | 2009 |
Effects of L-arginine on 7-nitroindazole-induced reference and working memory performance of rats.
Topics: Animals; Arginine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Indazoles; Male; Memory; Rats; Rats, Wistar | 2009 |
Endothelial nitric oxide synthase activity involves in the protective effect of ascorbic acid against penicillin-induced epileptiform activity.
Topics: Analysis of Variance; Animals; Antioxidants; Arginine; Ascorbic Acid; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Electroencephalography; Enzyme Inhibitors; Epilepsy; Free Radical Scavengers; Indazoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Penicillins; Rats; Rats, Wistar | 2010 |
Interaction of leptin and nitric oxide pathway on penicillin-induced epileptiform activity in rats.
Topics: Animals; Anticonvulsants; Arginine; Brain; Convulsants; Electroencephalography; Enzyme Inhibitors; Indazoles; Leptin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Penicillins; Rats; Rats, Wistar; Seizures; Signal Transduction | 2010 |
Involvement of nitric oxide-cGMP pathway in the anticonvulsant effects of lithium chloride on PTZ-induced seizure in mice.
Topics: Animals; Anticonvulsants; Arginine; Convulsants; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indazoles; Injections, Intraperitoneal; Lithium Chloride; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pentylenetetrazole; Phosphodiesterase Inhibitors; Piperazines; Purines; Seizures; Sildenafil Citrate; Sulfones; Treatment Outcome | 2010 |
Critical role of nitric oxide on nicotine-induced hyperactivation of dopaminergic nigrostriatal system: Electrophysiological and neurochemical evidence in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Action Potentials; Analysis of Variance; Animals; Arginine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Indazoles; Male; Microdialysis; Neurons; NG-Nitroarginine Methyl Ester; Nicotine; Nicotinic Agonists; Nitric Oxide; Rats; Rats, Sprague-Dawley; Substantia Nigra; Time Factors | 2010 |
Agmatine enhances the anticonvulsant effect of lithium chloride on pentylenetetrazole-induced seizures in mice: Involvement of L-arginine/nitric oxide pathway.
Topics: Agmatine; Analysis of Variance; Animals; Antidepressive Agents; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Indazoles; Lithium Chloride; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Seizures; Signal Transduction | 2010 |
Nitric oxide is involved in the regulation of marble-burying behavior.
Topics: Agmatine; Animals; Arginine; Behavior, Animal; Citalopram; Imidazoles; Indazoles; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type I; Obsessive-Compulsive Disorder; Paroxetine; Selective Serotonin Reuptake Inhibitors | 2010 |
In vitro and in vivo induction and activation of nNOS by LPS in oligodendrocytes.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Analysis of Variance; Animals; Animals, Newborn; Arginine; Basic Helix-Loop-Helix Transcription Factors; Brain; Cell Survival; Cells, Cultured; Citrulline; Corpus Callosum; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Indazoles; Lipopolysaccharides; Nerve Tissue Proteins; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; O Antigens; Oligodendroglia; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Stem Cells; Tritium | 2010 |
Myricitrin, a nitric oxide and protein kinase C inhibitor, exerts antipsychotic-like effects in animal models.
Topics: Animals; Antipsychotic Agents; Apomorphine; Arginine; Catalepsy; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Flavonoids; Indazoles; Male; Mice; Motor Activity; Nitric Oxide; Phytotherapy; Plant Leaves; Plant Preparations; Protein Kinase C; Psychotic Disorders; Rats; Rats, Wistar; Stereotyped Behavior; Syzygium; Tamoxifen | 2011 |
Involvement of nitric oxide-cGMP pathway in the antidepressant-like effect of ascorbic acid in the tail suspension test.
Topics: Animals; Antidepressive Agents; Arginine; Ascorbic Acid; Cyclic GMP; Depression; Disease Models, Animal; Dizocilpine Maleate; Enzyme Inhibitors; Exploratory Behavior; Female; Hindlimb Suspension; Indazoles; Mice; N-Methylaspartate; Nitric Oxide; Oxadiazoles; Piperazines; Purines; Quinoxalines; Signal Transduction; Sildenafil Citrate; Sulfones | 2011 |
Antidepressant-like effect of 1-(7-methoxy-2-methyl-1,2,3,4-tetrahydro-isoquinolin-4-YL)-cyclohexanol, a putative trace amine receptor ligand involves l-arginine-nitric oxide-cyclic guanosine monophosphate pathway.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Arginine; Biogenic Amines; Brain Chemistry; Cyclic GMP; Cyclohexanols; Depression; Guanylate Cyclase; Indazoles; Isoquinolines; Male; Methylene Blue; Mice; Motor Activity; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Piperazines; Purines; Signal Transduction; Sildenafil Citrate; Sulfones; Swimming | 2011 |
Evidence for the involvement of neuronal nitric oxide synthase and soluble guanylate cyclase on cognitive functions in rats.
Topics: Animals; Arginine; Avoidance Learning; Cognition; Guanylate Cyclase; Indazoles; Male; Memory; Memory, Short-Term; Nitric Oxide Synthase Type I; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Retention, Psychology; Soluble Guanylyl Cyclase | 2011 |
Protease-activated receptor-1 cleaved at R46 mediates cytoprotective effects.
Topics: Amino Acid Sequence; Antibodies; Arginine; Binding Sites, Antibody; Cytoprotection; Endothelial Cells; HEK293 Cells; Humans; Indazoles; Molecular Sequence Data; Peptide Fragments; Protein C; Protein Conformation; Receptor, PAR-1; Receptors, Thrombin; RNA Interference; Signal Transduction; Staurosporine; Structure-Activity Relationship; Thrombin; Transfection; Urea | 2012 |
Aminoguanidine attenuates hypertension, whereas 7-nitroindazole exacerbates kidney damage in spontaneously hypertensive rats: the role of nitric oxide.
Topics: Amidohydrolases; Animals; Arginine; Blood Pressure; Citrulline; Guanidines; Hypertension; Indazoles; Kidney Diseases; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Rats; Rats, Inbred SHR; Sodium Chloride, Dietary; Up-Regulation | 2013 |
Role of oxidative stress and inducible nitric oxide synthase in morphine-induced tolerance and dependence in mice. Effect of alpha-lipoic acid.
Topics: Animals; Arginine; Brain; Drug Tolerance; Enzyme Inhibitors; Glutamic Acid; Glutathione; Indazoles; Male; Malondialdehyde; Mice; Morphine; Morphine Dependence; Nitric Oxide Synthase Type II; Oxidative Stress; Thioctic Acid | 2013 |
Nitric oxide signaling contributes to ectopic orofacial neuropathic pain.
Topics: Animals; Arginine; Enzyme Inhibitors; Enzyme Precursors; Facial Pain; Hyperalgesia; Indazoles; Lip; Male; Mandibular Nerve; Neural Pathways; Neuralgia; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pain Threshold; Rats; Rats, Sprague-Dawley; Sensory Thresholds; Signal Transduction; Touch; Trigeminal Ganglion; Trigeminal Nerve Injuries | 2013 |
Effects of 7-NI and ODQ on memory in the passive avoidance, novel object recognition, and social transmission of food preference tests in mice.
Topics: Animals; Anxiety; Arginine; Avoidance Learning; Exploratory Behavior; Food Preferences; Indazoles; Male; Memory; Mice; Mice, Inbred BALB C; Motor Activity; Oxadiazoles; Quinoxalines; Smell; Social Behavior | 2014 |
Involvement of nitric oxide (NO) signaling pathway in the antidepressant action of the total flavonoids extracted from Xiaobuxin-Tang.
Topics: Animals; Antidepressive Agents; Arginine; Drugs, Chinese Herbal; Flavonoids; Guanidines; Indazoles; Male; Mice, Inbred ICR; Motor Activity; Nitric Oxide; Nitric Oxide Synthase; Signal Transduction | 2014 |
Involvement of neuronal nitric oxide synthase in desensitisation of µ-opioid receptors in the rat locus coeruleus.
Topics: Action Potentials; Animals; Arginine; Citrulline; Dose-Response Relationship, Drug; Enkephalin, Methionine; Ferricyanides; Indazoles; Locus Coeruleus; Male; Neural Inhibition; Nitric Oxide Synthase Type I; Nitroprusside; Norepinephrine; Ornithine; Rats; Receptors, Opioid, mu; Thiourea | 2014 |
The effect of a selective neuronal nitric oxide synthase inhibitor 3-bromo 7-nitroindazole on spatial learning and memory in rats.
Topics: Animals; Arginine; Brain-Derived Neurotrophic Factor; Hippocampus; Indazoles; Male; Memory; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; Spatial Learning | 2015 |
Divergent effects of L-arginine-NO pathway modulators on diazepam and flunitrazepam responses in NOR task performance.
Topics: Animals; Arginine; Diazepam; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flunitrazepam; GABA Modulators; Indazoles; Male; Memory Disorders; Motor Activity; Nitric Oxide; Psychotropic Drugs; Rats, Wistar; Recognition, Psychology | 2015 |
The Effects of Sub-Chronic Treatment with Aripiprazole on Pentylenetetrazole- and Electroshock-Induced Seizures in Mice: The Role of Nitric Oxide.
Topics: Animals; Anticonvulsants; Arginine; Aripiprazole; Convulsants; Electroshock; Guanidines; Indazoles; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pentylenetetrazole; Seizures | 2015 |
The effect of acute aripiprazole treatment on chemically and electrically induced seizures in mice: The role of nitric oxide.
Topics: Animals; Anticonvulsants; Antipsychotic Agents; Arginine; Aripiprazole; Convulsants; Dose-Response Relationship, Drug; Electroshock; Enzyme Inhibitors; Guanidines; Indazoles; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pentylenetetrazole; Seizures | 2015 |
Antidepressant-like effect of quercetin in bulbectomized mice and involvement of the antioxidant defenses, and the glutamatergic and oxidonitrergic pathways.
Topics: Animals; Antidepressive Agents; Antioxidants; Arginine; Behavior, Animal; Disease Models, Animal; Drug Synergism; Fluoxetine; Hippocampus; Indazoles; Male; Methylene Blue; Mice; N-Methylaspartate; Olfactory Bulb; Oxidative Stress; Quercetin; Signal Transduction; Sildenafil Citrate | 2015 |
Involvement of nitric oxide in anticompulsive-like effect of agmatine on marble-burying behaviour in mice.
Topics: Agmatine; Animals; Arginine; Behavior, Animal; Brain; Calcium Carbonate; Dose-Response Relationship, Drug; Indazoles; Male; Mice; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Obsessive-Compulsive Disorder | 2016 |
Possible involvement of nitrergic and opioidergic systems in the modulatory effect of acute chloroquine treatment on pentylenetetrazol induced convulsions in mice.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Anticonvulsants; Arginine; Chloroquine; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Hippocampus; Indazoles; Male; Mice; Naltrexone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Pentylenetetrazole; Seizures; Signal Transduction; Time Factors | 2016 |
The involvement of NMDA receptor/NO/cGMP pathway in the antidepressant like effects of baclofen in mouse force swimming test.
Topics: Animals; Antidepressive Agents; Arginine; Baclofen; Cyclic GMP; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Indazoles; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phosphodiesterase 5 Inhibitors; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Sildenafil Citrate; Stress, Psychological; Swimming | 2016 |
Possible involvement of L-arginine-nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) signaling pathway in the antidepressant-like effect of Wuling mycelia powder in rat.
Topics: Animals; Antidepressive Agents; Arginine; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Feeding Behavior; Food Preferences; Hippocampus; Indazoles; Male; Methylene Blue; Mycelium; Nitric Oxide; Powders; Rats, Sprague-Dawley; Signal Transduction; Sildenafil Citrate; Stress, Psychological; Sucrose | 2016 |
A Comparison of the Effects of Neuronal Nitric Oxide Synthase and Inducible Nitric Oxide Synthase Inhibition on Cartilage Damage.
Topics: Animals; Arginine; Cartilage; Enzyme Inhibitors; Guanidines; Indazoles; Male; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Stifle | 2016 |
The Importance of L-Arginine:NO:cGMP Pathway in Tolerance to Flunitrazepam in Mice.
Topics: Animals; Arginine; Cyclic GMP; Drug Interactions; Drug Tolerance; Flunitrazepam; Indazoles; Male; Mice; Motor Skills; NG-Nitroarginine Methyl Ester; Nitric Oxide; Signal Transduction; Sildenafil Citrate | 2017 |
Fish oil prevents rodent anxious states comorbid with diabetes: A putative involvement of nitric oxide modulation.
Topics: Amygdala; Animals; Anxiety; Arginine; Diabetes Mellitus, Experimental; Disease Models, Animal; Enzyme Inhibitors; Fish Oils; Hippocampus; Indazoles; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Periaqueductal Gray; Rats; Rats, Wistar; Streptozocin | 2017 |
Neuronal nitric oxide synthase is involved in CB/TRPV1 signalling: Focus on control of hippocampal hyperexcitability.
Topics: Action Potentials; Analysis of Variance; Animals; Anticonvulsants; Arginine; Benzoxazines; Cannabinoids; Capsaicin; Electric Stimulation; Enzyme Inhibitors; Hippocampus; Indazoles; Male; Morpholines; Naphthalenes; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; Rosaniline Dyes; Sensory System Agents; Signal Transduction; Time Factors; TRPV Cation Channels | 2017 |
Protease-activated receptor 1 inhibition protects mice against thrombin-dependent respiratory syncytial virus and human metapneumovirus infections.
Topics: Animals; Arginine; Cells, Cultured; Female; Humans; Indazoles; Metapneumovirus; Mice; Oligopeptides; Paramyxoviridae Infections; Pipecolic Acids; Receptor, PAR-1; Respiratory Syncytial Virus, Human; Sulfonamides; Thrombin; Urea; Virus Replication; Weight Loss | 2018 |
Nitric oxide involvement in additive antidepressant-like effect of agmatine and lithium in mice forced swim test.
Topics: Agmatine; Animals; Antidepressive Agents; Arginine; Drug Therapy, Combination; Guanidines; Indazoles; Lithium Compounds; Male; Mice; Mood Disorders; NG-Nitroarginine Methyl Ester; Nitric Oxide; Signal Transduction; Swimming | 2018 |
ADMA, homocysteine and redox status improvement affected by 7-nitroindazole in spontaneously hypertensive rats.
Topics: Animals; Aorta; Arginine; Biomarkers; Disease Models, Animal; Enzyme Inhibitors; Heart Ventricles; Homocysteine; Hypertension; Indazoles; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxidation-Reduction; Rats, Inbred SHR | 2018 |
The role of nitric oxide-cGMP pathway in selegiline antidepressant-like effect in the mice forced swim test.
Topics: Animals; Antidepressive Agents; Arginine; Cyclic GMP; Drug Synergism; Fluoxetine; Guanidines; Hippocampus; Immobility Response, Tonic; Indazoles; Male; Methylene Blue; Mice; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Prefrontal Cortex; Selegiline; Signal Transduction; Sildenafil Citrate; Swimming | 2018 |
(‑)Epigallocatechin‑3‑gallate attenuates anesthesia‑induced memory deficit in young mice via modulation of nitric oxide expression.
Topics: Anesthesia; Animals; Antioxidants; Apoptosis; Arginine; Biomarkers; Catechin; Disease Models, Animal; Indazoles; Male; Memory; Memory Disorders; Mice; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type I; Oxidative Stress | 2018 |
Pharmacological evidence for the relationship between the NMDA receptor and nitric oxide pathway and the antidepressant-like effects of glucagon-like peptide-2 in the mouse forced-swim test.
Topics: Animals; Antidepressive Agents; Arginine; Cyclic GMP; Depression; Dizocilpine Maleate; Glucagon-Like Peptide 2; Indazoles; Male; Methylene Blue; Mice; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phosphodiesterase 5 Inhibitors; Receptors, N-Methyl-D-Aspartate; Serine; Signal Transduction; Sildenafil Citrate; Swimming | 2019 |
Coenzyme Q10 increases absence seizures in WAG/Rij rats: The role of the nitric oxide pathway.
Topics: Action Potentials; Animals; Arginine; Dose-Response Relationship, Drug; Electrocorticography; Indazoles; Male; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Transgenic; Seizures; Signal Transduction; Ubiquinone | 2019 |
Doxorubicin combined with betulinic acid or lonidamine in RGD ligand-targeted pH-sensitive micellar system for ovarian cancer treatment.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Arginine; Aspartic Acid; Betulinic Acid; Cell Line, Tumor; Doxorubicin; Drug Carriers; Drug Compounding; Drug Liberation; Female; Glycine; Humans; Hydrogen-Ion Concentration; Indazoles; Leukocyte Count; Ligands; Mice; Micelles; Oligopeptides; Ovarian Neoplasms; Pentacyclic Triterpenes; Tissue Distribution; Triterpenes; Xenograft Model Antitumor Assays | 2019 |
Essential role for neuronal nitric oxide synthase in acute ethanol-induced motor impairment.
Topics: Alcohol-Induced Disorders, Nervous System; Animals; Arginine; Cerebellar Ataxia; Cerebellum; Enzyme Inhibitors; Ethanol; Frontal Lobe; Indazoles; Male; Nitric Oxide Synthase Type I; Psychomotor Disorders; Rats, Sprague-Dawley | 2020 |
NMDA-induced nitric oxide generation and CREB activation in central nervous system is dependent on eukaryotic elongation factor 2 kinase.
Topics: Animals; Arginine; Central Nervous System; Chickens; Cyclic AMP Response Element-Binding Protein; Cycloheximide; Elongation Factor 2 Kinase; Indazoles; Male; N-Methylaspartate; Nitric Oxide; Phosphorylation; Pyridines; Pyrimidines; Rats | 2020 |