gefitinib and triptolide
gefitinib has been researched along with triptolide in 3 studies
Compound Research Comparison
| Studies (gefitinib) | Trials (gefitinib) | Recent Studies (post-2010) (gefitinib) | Studies (triptolide) | Trials (triptolide) | Recent Studies (post-2010) (triptolide) |
|---|---|---|---|---|---|
| 5,231 | 566 | 2,919 | 1,158 | 6 | 820 |
Protein Interaction Comparison
| Protein | Taxonomy | gefitinib (IC50) | triptolide (IC50) |
|---|---|---|---|
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.04 | |
| Proteinase-activated receptor 2 | Homo sapiens (human) | 0.0185 |
Research
Studies (3)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ | 1 |
| Liu, G; Liu, H; Ma, T; Zhang, X | 1 |
| Cui, H; Gong, X; Jin, X; Li, F; Wang, J; Wang, W | 1 |
Other Studies
3 other study(ies) available for gefitinib and triptolide
| Article | Year |
|---|---|
Identification of potent Yes1 kinase inhibitors using a library screening approach.
Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
[Sequence-dependent Effect of Triptolide with Gefitinib on the Proliferation
and Apoptosis of Lung Adenocarcinoma Cell H1975].
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Diterpenes; Epoxy Compounds; ErbB Receptors; Gefitinib; Humans; Lung Neoplasms; Phenanthrenes; Protein Kinase Inhibitors; Quinazolines | 2015 |
Triptolide inhibits epithelial‑mesenchymal transition and induces apoptosis in gefitinib‑resistant lung cancer cells.
Topics: A549 Cells; Adenocarcinoma of Lung; Animals; Antigens, CD; Cadherins; Cell Proliferation; Cell Survival; Diterpenes; Drug Resistance, Neoplasm; Drug Synergism; Epithelial-Mesenchymal Transition; Epoxy Compounds; Gefitinib; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Mice; Phenanthrenes; Xenograft Model Antitumor Assays | 2020 |