fentanyl and u-50488

fentanyl has been researched along with u-50488 in 69 studies

Research

Studies (69)

Timeframe	Studies, this research(%)	All Research%
pre-1990	23 (33.33)	18.7374
1990's	28 (40.58)	18.2507
2000's	13 (18.84)	29.6817
2010's	4 (5.80)	24.3611
2020's	1 (1.45)	2.80

Authors

Authors	Studies
Adapa, ID; Auh, JS; Berzetei-Gurske, IP; Brandt, SR; Craymer, K; Farrington, L; Haggart, D; Kennedy, JM; O'Brien, A; Polgar, WE; Rodriguez, L; Schwartz, RW; Toll, L; White, A	1
Bednarski, M; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pękala, E; Powroźnik, B; Słoczyńska, K; Walczak, M; Waszkielewicz, AM; Żesławska, E	1
Avery, BA; Behnke, M; Chear, NJ; Hiranita, T; Kamble, SH; León, F; McCurdy, CR; McMahon, LR; Obeng, S; Patel, A; Ramanathan, S; Reeves, ME; Restrepo, LF; Sharma, A	1
Gintzler, AR; Xu, H	2
Lin, FS; Wang, CQ; Zhu, GY	1
Mueller, JL; Quock, RM	1
Dong, XW; Headley, PM; Parsons, CG	1
Headley, PM; Herrero, JF	1
Armstrong, RA; Rooney, KF; Sewell, RD	1
Mueller, J; Quock, RM	1
Dykstra, LA; Negus, SS; Picker, MJ	3
Negus, SS; Picker, MJ; Powell, KR	1
Cowan, A; Murray, CW	1
Buydens, P; Finné, E; Govaerts, J; Matton, A; Vanhaelst, L	1
Clarke, G; Davison, I; MacMillan, SJ; Wright, DM	1
Doty, P; Dykstra, LA; Mattox, SR; Negus, SS; Picker, MJ	1
Bansinath, M; Puig, MM; Ramabadran, K; Turndorf, H	2
Yaksh, TL	1
Berde, CB; Chang, HM; Holz, GG; Kream, RM; Steward, GF	1
France, CP; Snyder, AM; Woods, JH	1
Headley, PM; Parsons, CG	2
Cornfeldt, M; Fielding, S; Gorney, B; Locke, KW	1
Blake, JW; DeQuick, D; Kamerling, S; Tai, C; Tobin, T; Weckman, TJ; Wood, T	1
Dykstra, LA; Picker, MJ	1
Rooney, KF; Sewell, RD	1
Gaumann, DM; Lucas, DL; Tyce, GM; Yaksh, TL	1
Frey, HH	1
Dykstra, LA; Massie, CA	1
Dykstra, LA; Negus, SS	1
Hayes, AG; Stewart, BR	1
Hayes, AG; Skingle, M; Tyers, MB	1
Hynes, MD; Leander, JD; Reel, JK; Zimmerman, DM	1
Schulz, R	1
Donahoe, J; Kamerling, S; Tobin, T; Weckman, T	1
Dykstra, LA; Picker, M	1
Bardon, T; Pairet, M; Ruckebusch, Y	1
Pairet, M; Ruckebusch, Y	1
Headley, PM; Herrero, JF; Thorn, SA	1
Bardon, T; Roger, T; Ruckebusch, Y	1
Shi, GG; Wei, DS; Xu, SF	1
Mama, KR; Pascoe, PJ; Steffey, EP	1
Morgan, D; Picker, MJ	1
Gebhart, GF; Sengupta, JN; Su, X	1
Angel, F; Chevalier, E; Dahl, SG; Friese, N; Junien, JL; Pascaud, X; Riviere, PJ	1
Rothe, KS; Stevens, CW	1
Mash, DC; Partilla, J; Rice, KC; Rothman, RB; Staley, JK	1
Picker, MJ; Smith, MA	1
Cao, XD; Cui, DF; Li, MY; Qi, ZW; Wu, GC; Xu, SF; Zhang, XL; Zhu, CB	1
Johnson, MD; Ko, MC; Tuchman, JE; Wiesenauer, K; Woods, JH	1
Kishioka, S; Ko, MC; Woods, JH	1
Carter, BL; Conklin, CA; Tiffany, ST	1
Chen, J; Chen, LW; Chi, ZQ; Feng, YP; Xu, XJ; Zhou, DH	1
Baker, AK; Hoffmann, VL; Meert, TF	2
Hall, SF; Loh, HH; Mizoguchi, H; Nagase, H; Narita, M; Sora, I; Tseng, LF; Uhl, GR; Wu, HE	1
Bolling, SF; McNish, R; Romano, MA; Seymour, EM; Traynor, JR	1
Gallantine, EL; Meert, TF	1
Planas, E; Pol, O; Poveda, R; Puig, MM; Romero, A; Sánchez, S	1
Ko, MC; Mukhopadhyay, P; Pascoe, JE; Rice, KC; Williams, KL; Woods, JH	1
Martin, KK; Stahlheber, BW; Stevens, CW	1
Bolte, C; Newman, G; Schultz, Jel J	1
Ko, MC; Lee, H; Rice, KC; Sukhtankar, DD	1
Buzby, D; Friscia, M; Kacinko, SL; Logan, BK; Mohr, AL; Papsun, D	1
Heller, NM; Maher, DP; Walia, D	1

Reviews

1 review(s) available for fentanyl and u-50488

Article	Year
Narcotic analgesics, their detection and pain measurement in the horse: a review. Equine veterinary journal, 1989, Volume: 21, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Butorphanol; Chromatography, Thin Layer; Cyclazocine; Ethylketocyclazocine; Etorphine; Fentanyl; Horses; Morphine; Pain Measurement; Pentazocine; Pyrrolidines; Radioimmunoassay; Receptors, Opioid	1989

Article

Year

Narcotic analgesics, their detection and pain measurement in the horse: a review.

Equine veterinary journal, 1989, Volume: 21, Issue:1

Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Butorphanol; Chromatography, Thin Layer; Cyclazocine; Ethylketocyclazocine; Etorphine; Fentanyl; Horses; Morphine; Pain Measurement; Pentazocine; Pyrrolidines; Radioimmunoassay; Receptors, Opioid

1989

Trials

1 trial(s) available for fentanyl and u-50488

Article	Year
Comparative effects of mu and kappa opiate agonists on the cecocolic motility in the pony. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 1994, Volume: 58, Issue:3 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Catheterization, Central Venous; Cecum; Colon; Cross-Over Studies; Fentanyl; Gastrointestinal Motility; Horses; Pyrrolidines; Receptors, Opioid, kappa	1994

Article

Year

Comparative effects of mu and kappa opiate agonists on the cecocolic motility in the pony.

Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 1994, Volume: 58, Issue:3

Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Catheterization, Central Venous; Cecum; Colon; Cross-Over Studies; Fentanyl; Gastrointestinal Motility; Horses; Pyrrolidines; Receptors, Opioid, kappa

1994

Other Studies

67 other study(ies) available for fentanyl and u-50488

Article	Year
Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications. NIDA research monograph, 1998, Volume: 178 Topics: Animals; Aorta, Thoracic; Cocaine; Cyclic AMP; Electric Stimulation; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Opioid-Related Disorders; Rats; Receptors, Dopamine; Receptors, Opioid; Receptors, Serotonin; Substance-Related Disorders	1998
Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents. Bioorganic & medicinal chemistry, 2016, Apr-15, Volume: 24, Issue:8 Topics: Amino Alcohols; Animals; Anticonvulsants; Chemistry, Physical; Dose-Response Relationship, Drug; Drug Design; Epilepsy; Male; Mice; Microsomes, Liver; Molecular Structure; Pilocarpine	2016
Investigation of the Adrenergic and Opioid Binding Affinities, Metabolic Stability, Plasma Protein Binding Properties, and Functional Effects of Selected Indole-Based Kratom Alkaloids. Journal of medicinal chemistry, 2020, 01-09, Volume: 63, Issue:1 Topics: Adrenergic Agents; Analgesics; Animals; Blood Proteins; CHO Cells; Cricetulus; Dopamine Agents; Guinea Pigs; Humans; Microsomes, Liver; Rats; Receptors, Adrenergic; Receptors, Opioid; Secologanin Tryptamine Alkaloids	2020
Opioid enhancement of evoked [Met5]enkephalin release requires activation of cholinergic receptors: possible involvement of intracellular calcium. Proceedings of the National Academy of Sciences of the United States of America, 1992, Mar-01, Volume: 89, Issue:5 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Atropine; Calcimycin; Calcium; Colforsin; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Evoked Potentials; Fentanyl; Guinea Pigs; Hexamethonium Compounds; In Vitro Techniques; Myenteric Plexus; Naloxone; Pyrrolidines; Receptors, Muscarinic; Receptors, Opioid; Sufentanil	1992
[Effects of microiontophoretically applied OMF and U-50488 on spontaneous discharges of respiration related units in the region of nucleus of solitary tract of rat]. Sheng li xue bao : [Acta physiologica Sinica], 1992, Volume: 44, Issue:6 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Depression, Chemical; Electrophysiology; Female; Fentanyl; Iontophoresis; Male; Medulla Oblongata; Naloxone; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid; Respiration	1992
Contrasting influences of 5-hydroxytryptamine receptors in nitrous oxide antinociception in mice. Pharmacology, biochemistry, and behavior, 1992, Volume: 41, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Dose-Response Relationship, Drug; Fentanyl; Male; Mice; Mice, Inbred Strains; Nitrous Oxide; Pyrrolidines; Receptors, Serotonin; Sufentanil	1992
Effects of intravenous mu and kappa opioid receptor agonists on sensory responses of convergent neurones in the dorsal horn of spinalized rats. British journal of pharmacology, 1991, Volume: 103, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Benzodiazepines; Fentanyl; Hot Temperature; Male; Morphine; Naloxone; Neurons, Afferent; Nociceptors; Physical Stimulation; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord	1991
The effects of sham and full spinalization on the systemic potency of mu- and kappa-opioids on spinal nociceptive reflexes in rats. British journal of pharmacology, 1991, Volume: 104, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Decerebrate State; Dose-Response Relationship, Drug; Fentanyl; Male; Morphine; Motor Neurons; Naloxone; Nociceptors; Pain; Physical Stimulation; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reflex; Spinal Cord	1991
Different G proteins mediate the opioid inhibition or enhancement of evoked [5-methionine]enkephalin release. Proceedings of the National Academy of Sciences of the United States of America, 1991, Jun-01, Volume: 88, Issue:11 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Fentanyl; GTP-Binding Proteins; Guinea Pigs; In Vitro Techniques; Kinetics; Muscle, Smooth; Myenteric Plexus; Narcotics; Pertussis Toxin; Pyrrolidines; Sufentanil; Virulence Factors, Bordetella	1991
Increased dopamine receptor sensitivity in the rat following acute administration of sufentanil, U50,488H and D-Ala2-D-Leu5-enkephalin. Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 343, Issue:5 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzazepines; Corpus Striatum; Enkephalin, Leucine-2-Alanine; Fentanyl; In Vitro Techniques; Locomotion; Male; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Stereotyped Behavior; Sufentanil; Tritium	1991
Protection by U-50,488H against beta-chlornaltrexamine antagonism of nitrous oxide antinociception in mice. Brain research, 1991, May-17, Volume: 549, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Analgesics; Animals; Fentanyl; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Nitrous Oxide; Pain; Pyrrolidines; Sufentanil	1991
Interactions between the discriminative stimulus effects of mu and kappa opioid agonists in the squirrel monkey. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Behavior, Animal; Buprenorphine; Drug Interactions; Fentanyl; Learning; Male; Morphinans; Naloxone; Narcotics; Pentobarbital; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Saimiri	1991
Differential cross-tolerance to mu and kappa opioid agonists in morphine-tolerant rats responding under a schedule of food presentation. Psychopharmacology, 1991, Volume: 103, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzomorphans; Chlorpromazine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Tolerance; Ethylketocyclazocine; Fentanyl; Food; Male; Methadone; Morphine; Naloxone; Narcotics; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reinforcement Schedule	1991
Tonic pain perception in the mouse: differential modulation by three receptor-selective opioid agonists. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Fentanyl; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Pain; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sufentanil	1991
The growth hormone secretory response to fentanyl in rat: an involvement of mu type receptors. Journal of endocrinological investigation, 1990, Volume: 13, Issue:11 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzomorphans; Dose-Response Relationship, Drug; Enkephalin, Leucine; Fentanyl; Growth Hormone; Male; Narcotic Antagonists; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu	1990
Interactions between mu and kappa opioid agonists in the rat drug discrimination procedure. Psychopharmacology, 1990, Volume: 102, Issue:4 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzodiazepines; Benzomorphans; Buprenorphine; Discrimination, Psychological; Dose-Response Relationship, Drug; Drug Interactions; Fentanyl; Male; Morphine; Pentobarbital; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu	1990
Differential activity of selective opioid agonists on hypothalamic magnocellular neuronal activity. Progress in clinical and biological research, 1990, Volume: 328 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Female; Fentanyl; Hypothalamus; Lactation; Neurons; Oxytocin; Pregnancy; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Vasopressins	1990
Discriminative stimulus properties of U50,488 and morphine: effects of training dose on stimulus substitution patterns produced by mu and kappa opioid agonists. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Benzomorphans; Cyclazocine; Discrimination Learning; Dose-Response Relationship, Drug; Ethylketocyclazocine; Fentanyl; Male; Methadone; Morphine; Naloxone; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu	1990
Effects of kappa- and mu-selective opiate agonists on colonic temperature in normoglycaemic and streptozotocin-treated hyperglycaemic mice. Pharmacology & toxicology, 1990, Volume: 66, Issue:5 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzeneacetamides; Body Temperature; Colon; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Fentanyl; Narcotics; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sufentanil	1990
Substance P release from knee joint afferent terminals: modulation by opioids. Brain research, 1988, Aug-23, Volume: 458, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Afferent Pathways; Animals; Capsaicin; Cats; Electric Stimulation; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Fentanyl; Hindlimb; Joints; Narcotics; Pyrrolidines; Reference Values; Sciatic Nerve; Substance P; Sufentanil	1988
Sufentanil, morphine, met-enkephalin, and kappa-agonist (U-50,488H) inhibit substance P release from primary sensory neurons: a model for presynaptic spinal opioid actions. Anesthesiology, 1989, Volume: 70, Issue:4 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Chick Embryo; Enkephalin, Methionine; Fentanyl; In Vitro Techniques; Morphine; Neurons, Afferent; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Spinal Cord; Substance P; Sufentanil	1989
Analgesic effects of phencyclidine-like drugs in rhesus monkeys. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Alfentanil; Analgesia; Analgesics; Anesthetics; Animals; Anticonvulsants; Dextrorphan; Dibenzocycloheptenes; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Fentanyl; Ketamine; Macaca mulatta; Phenazocine; Phencyclidine; Pyrrolidines	1989
Hyperglycemia does not modify the pupillary effects of mu and kappa opiate agonists in mice. Journal of ocular pharmacology, 1989,Spring, Volume: 5, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzeneacetamides; Blood Glucose; Fentanyl; Half-Life; Hyperglycemia; Male; Mice; Morphine; Narcotics; Pupil; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu	1989
Spinal antinociceptive actions of mu- and kappa-opioids: the importance of stimulus intensity in determining 'selectivity' between reflexes to different modalities of noxious stimulus. British journal of pharmacology, 1989, Volume: 98, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Benzodiazepines; Decerebrate State; Electrophysiology; Fentanyl; Narcotics; Neurons; Nociceptors; Pain; Physical Stimulation; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reflex	1989
On the selectivity of intravenous mu- and kappa-opioids between nociceptive and non-nociceptive reflexes in the spinalized rat. British journal of pharmacology, 1989, Volume: 98, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Anesthetics; Animals; Decerebrate State; Fentanyl; Injections; Morphine; Motor Neurons; Narcotics; Nociceptors; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reflex	1989
Mu-opioid component of the ethylketocyclazocine (EKC) discriminative stimulus in the rat. Psychopharmacology, 1989, Volume: 99, Issue:4 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Cyclazocine; Discrimination, Psychological; Dose-Response Relationship, Drug; Ethylketocyclazocine; Fentanyl; Male; Morphine; Naloxone; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, mu	1989
Kappa antagonist effects of buprenorphine in the rat drug-discrimination procedure. NIDA research monograph, 1989, Volume: 95 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Brain; Buprenorphine; Discrimination Learning; Dose-Response Relationship, Drug; Fentanyl; Morphine; Perceptual Masking; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu	1989
Discriminative stimulus effects of mu and kappa opioids in the pigeon: analysis of the effects of full and partial mu and kappa agonists. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 249, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzodiazepines; Benzomorphans; Columbidae; Cyclazocine; Discrimination Learning; Ethylketocyclazocine; Fentanyl; Morphinans; Naloxone; Narcotics; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu	1989
Evaluation of selective actions of dopamine D-1 and D-2 receptor agonists and antagonists on opioid antinociception. European journal of pharmacology, 1989, Sep-22, Volume: 168, Issue:3 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Dopamine Agents; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ergolines; Fentanyl; Injections, Intraventricular; Male; Mice; Narcotics; Nociceptors; Pyrrolidines; Quinpirole; Reaction Time; Receptors, Dopamine; Sufentanil; Sulpiride	1989
Opioids preserve the adrenal medullary response evoked by severe hemorrhage: studies on adrenal catecholamine and met-enkephalin secretion in halothane anesthetized cats. Anesthesiology, 1988, Volume: 68, Issue:5 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenal Medulla; Anesthesia, Inhalation; Animals; Catecholamines; Cats; Endorphins; Enkephalin, Methionine; Fentanyl; Halothane; Hemorrhage; Pyrrolidines; Receptors, Opioid; Sufentanil	1988
Effect of mu- and kappa-opioid agonists on the electroconvulsive seizure threshold in mice and antagonism by naloxone and MR 2266. Pharmacology & toxicology, 1988, Volume: 62, Issue:3 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzeneacetamides; Benzodiazepines; Benzomorphans; Electroshock; Fentanyl; Male; Mice; Morphinans; Morphine; Nalbuphine; Naloxone; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Seizures	1988
Antagonism of the analgesic effects of mu and kappa opioid agonists in the squirrel monkey. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:3 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Animals; Azocines; Benzomorphans; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Fentanyl; Male; Methadone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Saimiri	1988
Kappa antagonist properties of buprenorphine in the shock titration procedure. European journal of pharmacology, 1988, Oct-26, Volume: 156, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Buprenorphine; Electroshock; Fentanyl; Male; Naltrexone; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Saimiri	1988
Effect of mu and kappa opioid receptor agonists on rat plasma corticosterone levels. European journal of pharmacology, 1985, Oct-08, Volume: 116, Issue:1-2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzodiazepines; Benzomorphans; Corticosterone; Dose-Response Relationship, Drug; Fentanyl; Male; Morphine; Naloxone; Naltrexone; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu	1985
Reversal by beta-funaltrexamine of the antinociceptive effect of opioid agonists in the rat. British journal of pharmacology, 1986, Volume: 88, Issue:4 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzodiazepines; Buprenorphine; Cyclazocine; Ethylketocyclazocine; Fentanyl; Male; Naltrexone; Pain; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu	1986
Use of beta-funaltrexamine to determine mu opioid receptor involvement in the analgesic activity of various opioid ligands. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Animals; Biological Assay; Buprenorphine; Butorphanol; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Etorphine; Fentanyl; Methadone; Mice; Morphine; Muscle Contraction; Nalbuphine; Nalorphine; Naltrexone; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, mu	1987
Dependence and cross-dependence in the guinea-pig myenteric plexus. Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 337, Issue:6 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Clonidine; Drug Tolerance; Fentanyl; Guinea Pigs; Male; Morphine Dependence; Muscle Contraction; Myenteric Plexus; Pertussis Toxin; Pyrrolidines; Virulence Factors, Bordetella	1988
Dose related effects of the kappa agonist U-50, 488H on behaviour, nociception and autonomic response in the horse. Equine veterinary journal, 1988, Volume: 20, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Autonomic Nervous System; Body Temperature; Chemical Phenomena; Chemistry; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Female; Fentanyl; Heart Rate; Horses; Locomotion; Male; Nociceptors; Pupil; Pyrrolidines; Respiration	1988
Comparison of the discriminative stimulus properties of U50,488 and morphine in pigeons. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:3 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Columbidae; Cyclazocine; Dextroamphetamine; Discrimination Learning; Dose-Response Relationship, Drug; Ethylketocyclazocine; Female; Fentanyl; Methadone; Morphine; Naloxone; Phenazocine; Phencyclidine; Pyrrolidines; Time Factors	1987
Opioid control of the ruminant stomach motility: functional importance of mu, kappa and delta receptors. Life sciences, 1984, Oct-22, Volume: 35, Issue:17 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Ethylketocyclazocine; Fentanyl; Gastrointestinal Motility; Morphine; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sheep; Stomach	1984
Opioid receptor agonists in the rabbit colon: comparison of in vivo and in vitro studies. Life sciences, 1984, Oct-15, Volume: 35, Issue:16 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Colon; Cyclazocine; Dynorphins; Electric Conductivity; Enkephalins; Ethylketocyclazocine; Fentanyl; Male; Morphine; Naloxone; Narcotics; Pyrrolidines; Rabbits; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu	1984
Stimulus intensity and the comparative efficacy of mu- and kappa-opioid agonists on nociceptive spinal reflexes in the rat. Brain research, 1994, Nov-14, Volume: 663, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Electric Stimulation; Fentanyl; Male; Pain; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reflex; Spinal Cord	1994
[Effect of agonists of opioid receptor on coronary arterial strips in porcine]. Sheng li xue bao : [Acta physiologica Sinica], 1994, Volume: 46, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Coronary Vessels; Fentanyl; Haloperidol; In Vitro Techniques; Morphine; Muscle Contraction; Muscle, Smooth, Vascular; Naloxone; Pyrrolidines; Receptors, Opioid; Swine	1994
Evaluation of the interaction of mu and kappa opioid agonists on locomotor behavior in the horse. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 1993, Volume: 57, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Drug Interactions; Fentanyl; Horses; Motor Activity; Pyrrolidines	1993
Discriminative stimulus effects of the 5HT1A agonist 8-OH-DPAT: attenuation by mu but not by kappa opioids. Psychopharmacology, 1995, Volume: 122, Issue:4 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesics; Animals; Benzomorphans; Discrimination Learning; Drug Therapy, Combination; Fentanyl; Male; Morphine; Narcotics; Pyrimidines; Pyrrolidines; Rats; Receptors, Opioid, kappa; Receptors, Opioid, mu; Serotonin Receptor Agonists	1995
Kappa, but not mu or delta, opioids attenuate responses to distention of afferent fibers innervating the rat colon. Gastroenterology, 1996, Volume: 111, Issue:4 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Afferent Pathways; Animals; Benzyl Compounds; Colon; Fentanyl; Male; Morphine; Propylamines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu	1996
Reversal by kappa-agonists of peritoneal irritation-induced ileus and visceral pain in rats. Life sciences, 1997, Volume: 60, Issue:9 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetic Acid; Analgesics; Animals; Benzofurans; Benzomorphans; Cyclazocine; Fentanyl; Gastric Emptying; Intestinal Pseudo-Obstruction; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Peritoneum; Pyrroles; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Thiophenes	1997
Supraspinal administration of opioids with selectivity for mu-, delta- and kappa-opioid receptors produces analgesia in amphibians. European journal of pharmacology, 1997, Jul-16, Volume: 331, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Benzofurans; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Female; Fentanyl; Injections, Intraventricular; Male; Morphine; Naltrexone; Narcotics; Pyrrolidines; Rana pipiens; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu	1997
Kappa2 opioid receptors in limbic areas of the human brain are upregulated by cocaine in fatal overdose victims. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Nov-01, Volume: 17, Issue:21 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adult; Amygdala; Benzeneacetamides; Benzomorphans; Binding, Competitive; Brain; Brain Chemistry; Caudate Nucleus; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Drug Overdose; Female; Fentanyl; Gyrus Cinguli; Humans; Isothiocyanates; Kinetics; Male; Morphinans; Protein Binding; Pyrrolidines; Receptors, Opioid, kappa; Tissue Distribution; Up-Regulation	1997
Tolerance and cross-tolerance to the rate-suppressing effects of opioids in butorphanol-treated rats: influence of maintenance dose and relative efficacy at the mu receptor. Psychopharmacology, 1998, Volume: 140, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Buprenorphine; Butorphanol; Dose-Response Relationship, Drug; Drug Tolerance; Fentanyl; Male; Naloxone; Phenobarbital; Rats; Rats, Long-Evans; Receptors, Opioid, mu; Sufentanil	1998
Antagonistic effect of orphanin FQ on opioid analgesia in rat. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1998, Volume: 19, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Analgesics; Analgesics, Opioid; Animals; Enkephalin, Leucine; Fentanyl; Injections, Intraventricular; Injections, Spinal; Male; Nociceptin; Opioid Peptides; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Opioid	1998
Local administration of mu or kappa opioid agonists attenuates capsaicin-induced thermal hyperalgesia via peripheral opioid receptors in rats. Psychopharmacology, 2000, Volume: 148, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Local; Animals; Azocines; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Fentanyl; Hot Temperature; Hyperalgesia; Injections, Subcutaneous; Male; Narcotic Antagonists; Pain; Pain Measurement; Rats; Rats, Wistar; Receptors, Opioid, kappa; Receptors, Opioid, mu	2000
Diltiazem enhances the analgesic but not the respiratory depressant effects of morphine in rhesus monkeys. European journal of pharmacology, 2000, May-26, Volume: 397, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Benzimidazoles; Calcium Channel Blockers; Clonidine; Diltiazem; Dose-Response Relationship, Drug; Drug Synergism; Female; Fentanyl; Heroin; Macaca mulatta; Male; Morphine; Nalbuphine; Pain Measurement; Receptors, Opioid; Respiration; Time Factors	2000
Associative and non-associative fentanyl tolerance in the rat: evaluation of cross tolerance with mu-and kappa-specific opioids. Psychopharmacology, 2000, Volume: 148, Issue:4 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Drug Tolerance; Fentanyl; Generalization, Stimulus; Male; Morphine; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid, kappa; Receptors, Opioid, mu	2000
Analysis of binding domain and function of chimeric mu/kappa opioid receptors to ohmefentanyl stereoisomers. Acta pharmacologica Sinica, 2001, Volume: 22, Issue:11 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Binding Sites; Chlorocebus aethiops; COS Cells; Cyclic AMP; Dynorphins; Fentanyl; Peptide Fragments; Protein Structure, Tertiary; Receptors, Opioid, kappa; Receptors, Opioid, mu; Recombinant Fusion Proteins; Stereoisomerism	2001
Dextromethorphan and ketamine potentiate the antinociceptive effects of mu- but not delta- or kappa-opioid agonists in a mouse model of acute pain. Pharmacology, biochemistry, and behavior, 2002, Volume: 74, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Area Under Curve; Benzamides; Dextromethorphan; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Fentanyl; Ketamine; Male; Mice; Morphine; Pain; Pain Measurement; Piperazines; Reaction Time; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sufentanil	2002
Interactions of NMDA antagonists and an alpha 2 agonist with mu, delta and kappa opioids in an acute nociception assay. Acta anaesthesiologica Belgica, 2002, Volume: 53, Issue:3 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Benzamides; Clonidine; Dextromethorphan; Dose-Response Relationship, Drug; Drug Synergism; Fentanyl; Ketamine; Male; Mice; Morphine; N-Methylaspartate; Pain; Pain Measurement; Piperazines; Reaction Time; Receptors, Opioid	2002
Lack of mu-opioid receptor-mediated G-protein activation in the spinal cord of mice lacking Exon 1 or Exons 2 and 3 of the MOR-1 gene. Journal of pharmacological sciences, 2003, Volume: 93, Issue:4 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Exons; Fentanyl; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Mice; Mice, Knockout; Morphine Derivatives; Nociceptin; Nociceptin Receptor; Oligopeptides; Opioid Peptides; Radioligand Assay; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord	2003
Differential effects of opioid peptides on myocardial ischemic tolerance. The Journal of surgical research, 2004, Jun-01, Volume: 119, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adaptation, Physiological; Animals; Cardiotonic Agents; Enkephalin, Leucine-2-Alanine; Fentanyl; Heart; In Vitro Techniques; Microscopy, Electron; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Opioid Peptides; Oxygen Consumption; Rabbits; Recovery of Function	2004
Attenuation of the gerbil writhing response by mu-, kappa- and delta-opioids, and NK-1, -2 and -3 receptor antagonists. Pharmacology, biochemistry, and behavior, 2004, Volume: 79, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Abdomen; Acetic Acid; Analgesics, Opioid; Animals; Behavior, Animal; Biphenyl Compounds; Butanols; Calcium Channel Blockers; Dose-Response Relationship, Drug; Female; Fentanyl; Gerbillinae; Malates; Morphine; Muscle Contraction; Neurokinin-1 Receptor Antagonists; Pain Measurement; Piperidines; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tetrazoles	2004
Anti-exudative effects of opioid receptor agonists in a rat model of carrageenan-induced acute inflammation of the paw. European journal of pharmacology, 2005, Mar-28, Volume: 511, Issue:2-3 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Benzamides; Capsaicin; Carrageenan; Cyclosporine; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Enkephalin, D-Penicillamine (2,5)-; Extravasation of Diagnostic and Therapeutic Materials; Fentanyl; Hindlimb; Histamine Antagonists; Inflammation; Male; Morphine; Narcotic Antagonists; Oxidopamine; p-Methoxy-N-methylphenethylamine; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu	2005
Effects of mu, kappa, and delta opioid receptor agonists on the function of hypothalamic-pituitary-adrenal axis in monkeys. Psychoneuroendocrinology, 2008, Volume: 33, Issue:4 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenocorticotropic Hormone; Analgesics, Opioid; Animals; Area Under Curve; Benzamides; Dose-Response Relationship, Drug; Female; Fentanyl; Hydrocortisone; Hypothalamo-Hypophyseal System; Macaca mulatta; Male; Piperazines; Pituitary-Adrenal System; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu	2008
Nociceptin produces antinociception after spinal administration in amphibians. Pharmacology, biochemistry, and behavior, 2009, Volume: 91, Issue:3 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetic Acid; Analgesics; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Interactions; Enkephalin, D-Penicillamine (2,5)-; Fentanyl; Injections, Spinal; Naltrexone; Nociceptin; Opioid Peptides; Pain Threshold; Peptide Fragments; Rana pipiens	2009
Kappa and delta opioid receptor signaling is augmented in the failing heart. Journal of molecular and cellular cardiology, 2009, Volume: 47, Issue:4 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Calcium Signaling; Cardiomegaly; Cardiomyopathies; Cricetinae; Cyclic AMP; Fentanyl; Heart Failure; Heart Function Tests; Heterotrimeric GTP-Binding Proteins; In Vitro Techniques; Myocardial Contraction; Opioid Peptides; Pertussis Toxin; Quinolines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Signal Transduction; Systole	2009
Differential effects of opioid-related ligands and NSAIDs in nonhuman primate models of acute and inflammatory pain. Psychopharmacology, 2014, Volume: 231, Issue:7 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acute Pain; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fentanyl; Hyperalgesia; Imidazoles; Inflammation; Macaca; Male; Nociceptive Pain; Pain Measurement; Piperazines; Receptors, Opioid; Spiro Compounds	2014
Analysis of Novel Synthetic Opioids U-47700, U-50488 and Furanyl Fentanyl by LC-MS/MS in Postmortem Casework. Journal of analytical toxicology, 2016, Volume: 40, Issue:9 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Analgesics, Opioid; Animals; Autopsy; Benzamides; Calibration; Chromatography, Liquid; Drug Overdose; Fentanyl; Furans; Gas Chromatography-Mass Spectrometry; Heroin; Humans; Male; Morphine; Sheep; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry	2016
Suppression of Human Natural Killer Cells by Different Classes of Opioids. Anesthesia and analgesia, 2019, Volume: 128, Issue:5 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Anesthesia; Buprenorphine; Enkephalin, D-Penicillamine (2,5)-; Fentanyl; Fluoresceins; Humans; Immunosuppression Therapy; K562 Cells; Killer Cells, Natural; Loperamide; Methadone; Morphinans; Morphine; Naloxone; Naltrexone; Succinimides; Toll-Like Receptor 4; Tramadol	2019

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