fentanyl has been researched along with naloxone in 647 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 242 (37.40) | 18.7374 |
| 1990's | 103 (15.92) | 18.2507 |
| 2000's | 99 (15.30) | 29.6817 |
| 2010's | 119 (18.39) | 24.3611 |
| 2020's | 84 (12.98) | 2.80 |
| Authors | Studies |
|---|---|
| Bagley, JR; Doorley, BM; Rudo, FG; Spaulding, T; Spencer, HK; Wynn, RL | 1 |
| Bell, GI; Chen, Y; Kong, H; Raynor, K; Reisine, T; Yasuda, K; Yu, L | 1 |
| Adapa, ID; Auh, JS; Berzetei-Gurske, IP; Brandt, SR; Craymer, K; Farrington, L; Haggart, D; Kennedy, JM; O'Brien, A; Polgar, WE; Rodriguez, L; Schwartz, RW; Toll, L; White, A | 1 |
| Bodinier, MC; Bonnet, B; Chapelain, B; Déprez, B; Eckhoff, C; Horvath, D; Poulain, R | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Colpaert, FC; Janssen, PA; Kuyps, JJ; Niemegeers, CJ | 1 |
| Kafer, ER; Marsh, HM | 1 |
| Rivet, P; Roujas, F | 1 |
| Dick, W; Knoche, E; Milewski, P; Traub, E | 1 |
| Jobard, J; Lallia, A; Maestracci, P; Orth, MF | 1 |
| Dick, W; Milewski, P | 1 |
| Khanna, VK; Pleuvry, BJ | 1 |
| Boureau, F; Cambier, J; Dehen, H; Gonce, M; Prier, S; Willer, JC | 1 |
| Boureau, F; Cambier, J; Dehen, H; Prier, S; Willer, JC | 1 |
| Creese, I; Feinberg, AP; Snyder, SH | 1 |
| Daskalopoulos, N; Laubie, M; Schmitt, H | 1 |
| Cukier, K; Cwizewicz-Adamska, J; Czekuć, E; Rondio, Z; Ryterski, S | 1 |
| Butler, DP; Driscoll, EJ; Gelfman, SS; Medlin, T; Sweet, JB; Wirdzck, PR | 1 |
| Davie, IT; Drummond, GB; Scott, DB | 1 |
| Campos, S; Flores, MR; Izquierdo, MD; Nalda, MA | 1 |
| Tammisto, T; Tigerstedt, I | 2 |
| Arndt, JO; Freye, E | 2 |
| Brückner, JB; Schmidt, D; Schneider, E; Schweichel, E | 1 |
| Saady, A | 1 |
| Patenaude, RP | 1 |
| Lefebvre, RA; Willems, JL | 1 |
| Azcona, A; Kubicki, S | 1 |
| Leander, JD | 1 |
| Doenicke, A; Hug, P; Kugler, J; Spatz, R; Zimmermann, W | 1 |
| Tigerstedt, I | 3 |
| Rolly, G | 1 |
| Hatano, Y; Toda, N | 1 |
| Patschke, D | 1 |
| Dryden, GE; McCammon, RL; Stoelting, RK; Viegas, OJ | 1 |
| Baasch, K; Reist, F; Schaer, H | 1 |
| Berlin, J; Dimai, W; Gattiker, R; Hossli, G | 1 |
| Doenicke, A; Hug, P; Kugler, J; Laub, M; Zimmermann, W | 1 |
| De Vos, V | 1 |
| Hill, RG; Mayer, ML | 1 |
| Arnér, S; Gordon, E | 1 |
| Haigh, JC | 1 |
| Aroński, A; Kübler, A | 1 |
| Cattaneo, AD; Graffigna, R; Rivara, A; Siani, C | 1 |
| Geevarghese, KP; Gray, LA; Shields, CB | 1 |
| Andersen, R; Dobloug, I; Refstad, S | 1 |
| Colpaert, FC; Janssen, PA; Niemegeers, CJ | 2 |
| Freye, E; Kuschinsky, K | 1 |
| Herz, A; Satoh, M; Zieglgänsberger, W | 1 |
| Smith, WD | 1 |
| Freye, E | 1 |
| Daskalopoulos, NT; Laubie, M; Schmitt, H | 1 |
| Smuts, GL | 1 |
| Costa, EM; Hoffmann, BB; Loew, GH | 1 |
| Gintzler, AR; Xu, H | 2 |
| Lin, FS; Wang, CQ; Zhu, GY | 1 |
| Wolfensohn, SE | 1 |
| Huttarsch, H; Lehmann, KA; Schroeder, B; Zech, D | 1 |
| Alvarez, L; Carmona, JA; Castillo-Olivares, JL; Escudero, C; Silva, L | 1 |
| Chi, ZQ; Gu, JJ; Zhao, GM | 1 |
| Chakrabarti, MK; Galletly, DC; Wang, C; Whitwam, JG | 1 |
| Brum, JM; Estafanous, FG; Ferrario, CM; Khairallah, PA; Yamanoue, T | 1 |
| Holtzman, SG; Paronis, CA | 1 |
| Coghill, RC; Frenk, H; Leshem, M; Mayer, DJ | 1 |
| Dong, XW; Headley, PM; Parsons, CG | 1 |
| Jang, Y; Yoburn, BC | 1 |
| Botschev, C; Müller, N | 1 |
| Gent, JP; Goodchild, CS; Serrao, JM | 1 |
| Boulter, N; Gent, JP; Goodchild, CS; Serrao, JM | 1 |
| Barnes, NM; Bunce, KT; Naylor, RJ; Rudd, JA | 1 |
| Headley, PM; Herrero, JF | 2 |
| Cesselin, F; De Witte, PA; Hamon, M; Laduron, PM; Levy, C; Mauborgne, A | 1 |
| Asmangulian, ET; Buniatian, AA; Mierbekov, EM; Ter-Mikaelian, DK; Trekova, NA | 1 |
| Hu, ST; Xu, T | 1 |
| Dykstra, LA; Negus, SS; Picker, MJ | 1 |
| Negus, SS; Picker, MJ; Powell, KR | 1 |
| Alvarez, L; Asher, K; Bergman, SA; Thut, PD; Wynn, RL | 1 |
| Chondreli, S; Fassoulaki, A; Sarantopoulos, C | 1 |
| Cruccu, G; Fabbri, A; Ferracuti, S; Leardi, MG; Manfredi, M | 1 |
| de Groat, WC; Nishizawa, O; Noto, H; Roppolo, JR; Sugaya, K; Tsuchida, S | 1 |
| Clark, R; Frye, J; Harchelroad, F; Hecker, J; Jehle, D; Lucid, EJ; Martin, M | 1 |
| Barna, I; de Jong, W; Ramirez-Gonzalez, MD; Wiegant, VM | 1 |
| Asanobu, T; Higashi, T; Kawakami, S; Kouno, K; Kurasako, T; Matsumoto, M; Naito, H; Tada, K; Takatori, M; Uchida, H | 1 |
| Barnes, RK | 1 |
| Achtari, R; Baasch, K; Schaer, H | 2 |
| Kreeger, TJ; Seal, US | 1 |
| Freye, E; Schenk, G | 1 |
| Doty, P; Dykstra, LA; Mattox, SR; Negus, SS; Picker, MJ | 1 |
| Lalinde, N; Moliterni, J; Ossipov, MH; Rudo, FG; Spaulding, TC; Spencer, HK; Wright, D | 1 |
| Besson, JM; Gobeaux, D; Guilbaud, G; Kayser, V; Lombard, MC | 1 |
| Kitchen, I; Yeadon, M | 2 |
| Takatori, M | 1 |
| Bloor, BC; Flacke, JW; Flacke, WE; Liu, MD; Mills, CA | 1 |
| Chai, XQ; Gao, YH | 1 |
| Donnerer, J; Lembeck, F | 1 |
| Foley, KM; Houde, RW; Inturrisi, CE; Moulin, DE; Nip, TJ; Reidenberg, B; Wallenstein, S; Weinberg, DS | 1 |
| Hall, RI; Hug, CC; Schwieger, IM; Szlam, F | 1 |
| Bailey, PL | 1 |
| Bergman, SA; Coro, C; Hyatt, J; Wynn, RL | 1 |
| Murkin, JM | 1 |
| Desjardins, PJ | 1 |
| Crozier, WC; Dannals, RF; Douglass, KH; Frost, JJ; Links, JM; Mayberg, HS; Ravert, HT; Wagner, HN; Wilson, AA | 1 |
| Stevens, CW; Yaksh, TL | 1 |
| Bullock, A; Dannals, RF; Frost, JF; Kuhar, MJ; Leonhardt, S; Lyon, RA; Price, DL; Rydelek, LT; Struble, RG; Titeler, M | 1 |
| Cornfeldt, M; Fielding, S; Gorney, B; Locke, KW | 1 |
| Dykstra, LA; Picker, MJ | 1 |
| Kampine, JP; Schmeling, WT; Warltier, DC | 1 |
| Jaffe, AB; Jaffe, JH; Sharpe, LG | 1 |
| Gintzler, AR; Smolens, I; Xu, H | 1 |
| Ebertz, JM; Hanifin, JM; Hermens, JM; Hirshman, CA | 1 |
| Abdelhamid, EM; Archer, S; Koolpe, GA; Michael, J; Michael, M; Nelson, WL; Simon, EJ | 1 |
| Meakin, G; Ryan, JP | 1 |
| Deshpande, JK; Maxwell, LG; Yaster, M | 1 |
| Gentil, B; Harf, A; Macquin-Mavier, I | 1 |
| Arroyo, JL; Castilla, A; Prieto, J; Serrano, M; Subirá, ML | 1 |
| Gillon, JY; Milne, B; Pujol, JF; Quintin, L | 1 |
| Brauer, FS; Cole, DJ; Drummond, JC; Hertzog, RE; Shapiro, HM | 1 |
| Frey, HH | 1 |
| Millan, MJ; Morris, BJ | 1 |
| Gaumann, DM; Stoddard, S; Tyce, GM; Yaksh, TL | 1 |
| Holtzman, SG | 1 |
| Janssen, PF; Laduron, PM; Poncet, J | 1 |
| Bloor, BC; Flacke, JW; Flacke, WE; Katz, RL; Kripke, BJ; Van Etten, AP; Warneck, CM; Wong, DH | 1 |
| Svensson, G; Valgardsson, A; Werner, O | 1 |
| Fontaine, J; Reuse, J | 1 |
| Martin, WR; Wettstein, JG | 1 |
| Durant, PA; Yaksh, TL | 1 |
| Durant, PA; Noueihed, RY; Yaksh, TL | 1 |
| Jensen, TS; Yaksh, TL | 1 |
| Shafer, A; Sung, ML; White, PF | 1 |
| Banerjee, AK; Dhasmana, KM; Erdmann, W | 2 |
| Morrison, S; Reis, DJ; Sapru, HN; Willette, RN | 1 |
| Heijna, MH; Hogenboom, F; Jacobson, AE; Mulder, AH; Rice, KC; Schoffelmeer, AN; Van Gelderen, JG | 1 |
| Koehler, RC; Traystman, RJ; Yaster, M | 2 |
| Chang, J; Fish, KJ | 1 |
| Wali, FA | 1 |
| Chakrabarti, M; Odensjö Swenzon, G; Sapsed-Byrne, S; Whitwam, JG | 1 |
| Gamse, R; Saria, A | 1 |
| Herz, A; Schulz, R; Seidl, E | 1 |
| Hayes, AG; Stewart, BR | 1 |
| Aoki, M; Collins, JG; Kitahata, LM; Senami, M | 1 |
| Frost, JJ; Smith, AC; Wagner, HN | 1 |
| Bice, AN; Dannals, RF; Frost, JJ; Lee, MC; Links, JM; Natarajan, TK; Ravert, HT; Wagner, HN; Wilson, AA; Wong, DF | 1 |
| Booth, NH; Brown, J; Clark, JD; Hatch, RC; Jernigan, AD; Lipham, IB; Wilson, RC | 1 |
| Bo, G; Chen-Yu, C | 1 |
| Amalric, M; Blasco, TA; Koob, GF; Lee, DE; Smith, NT; Swerdlow, NR | 1 |
| Abbott, FV; Franklin, KB; Libman, RB | 1 |
| Poncet, J; Reny-Palasse, V; Rips, R | 1 |
| Amalric, M; Blasco, TA; Koob, GF; Lee, D; Smith, NT; Swerdlow, NR | 1 |
| Tan, PP; Wong, KL | 1 |
| Colpaert, FC; Janssen, PA | 3 |
| Benhamou, D; Carli, P; Ecoffey, Cl; Gross, JB; Gueneron, JP | 1 |
| Eustache, ML; Oksenhendler, G; Petit, J; Pigot, B; Winckler, C | 1 |
| Cartwright, DP | 1 |
| Blasco, TA; Cline, EJ; Koob, GF; Smith, NT; Weinger, MB | 1 |
| Bloor, BC; Davis, LJ; Flacke, JW; Flacke, WE; Miller, JD; Mills, CA | 1 |
| Bovill, JG; Burm, AG; Hennis, PJ; Lemmens, HJ | 1 |
| Mahla, ME; Moneta, MD; White, SE | 1 |
| Cherry, DA; Cousins, MJ; Gourlay, GK; McLachlan, M | 1 |
| Harp, JR; Shupak, RC | 1 |
| Boysen, K; Chraemmer-Jørgensen, B; Hertel, S; Poulsen, NJ; Risbo, A | 1 |
| Mirenda, J; Tabatabai, M; Wong, K | 1 |
| Dendo, I; Hori, T; Matsumoto, I; Matsumoto, N; Nagasaka, H; Nagasaka, I; Sato, I; Takano, Y | 1 |
| Couture, LJ; Edmonds, HL; Paloheimo, MP; Rigor, BM | 1 |
| Amar, R; Caspi, J; Klausner, JM; Merin, G; Rozin, RR; Safadi, T | 1 |
| Dykstra, LA; Picker, M | 1 |
| Aoki, M; Collins, JG; Kitahata, LM; Kumeta, Y; Murata, K; Nishio, Y | 1 |
| Cafaggi, G; Di Gregorio, AM; Miele, E; Scafuro, M; Tommasino, C | 1 |
| Levi, V; Sadée, W; Scott, JC; White, PF | 1 |
| Chapman, CR | 1 |
| Borgdorff, P; de Neef, JH; Porsius, AJ; van Rooij, HH | 1 |
| Hovav, E; Weinstock, M | 1 |
| Bailey, PL; Clark, NJ; Clissold, MA; East, KA; Pace, NL; Rozendaal, W; Stanley, TH; van de Pol, P; van Vreeswijk, H | 1 |
| Dionne, RA; Dubner, R; Goldstein, DS; Hargreaves, KM; Mueller, GP | 1 |
| Campbell, JN; Khan, AA; Meyer, RA; Raja, SN | 1 |
| Bonnet, F; Debras, C; Kergrohen, F; Lafosse, JE; Loriferne, JF; Salvat, A | 1 |
| Doorley, BM; Sapru, HN; Willette, RN | 1 |
| Velasco de Parra, ML; Velasco, F; Velasco, M | 1 |
| Collins, JG; Kitahata, LM; Matsumoto, M; Suzukawa, M; Tabatabai, M; Tanaka, A; Yuge, O | 1 |
| Dai, S; Ho, MM; Ogle, CW | 1 |
| Bardon, T; Roger, T; Ruckebusch, Y | 1 |
| Baker, JR; Gatesman, TJ | 1 |
| Myers, DE; Myslinski, NR; Wynn, RL | 1 |
| Lux, B; Schulz, R | 1 |
| Lisander, B; Stenqvist, O | 1 |
| Montel, H; Starke, K; Weber, F | 1 |
| Hartung, E; Huse, K; Nadjmabadi, MH | 1 |
| Granada, MG; Greenfield, W | 1 |
| Foldes, FF | 1 |
| Armijo, JA; Delgado, G; Flórez, J | 1 |
| Paddleford, RR; Short, CE | 1 |
| Montel, H; Starke, K | 1 |
| Bageant, T; Petty, C | 1 |
| Lal, H; Van Nueten, JM | 1 |
| Villiger, JW | 1 |
| Bagley, JR; Baker, JK; Riley, TN; Skelton, RE | 1 |
| Amsterdam, EA; Henderson, GL; Mason, DT; Rendig, SV | 1 |
| Dauthier, C; Gaudy, JH; Willer, JC | 1 |
| Combie, J; Dougherty, J; Nugent, EC; Shults, T; Tobin, T | 1 |
| Deen, L; Helmers, JH; van Leeuwen, L | 1 |
| Brown, JH; Pleuvry, BJ | 1 |
| Blazsó, G; Minker, E; Végh, A | 1 |
| Adam, A; Deen, L; Giezen, J; Helmers, JH; Van Leeuwen, L | 1 |
| Booth, NH; Crawford, LM; Hatch, RC | 1 |
| Litchfield, NB | 1 |
| Freye, E; Hartung, E; Kaliebe, S | 1 |
| Gommeren, W; Leysen, JE | 1 |
| De Potter, WP; Gommeren, W; Hermans, B; Leysen, JE | 1 |
| Cookson, RF; Niemegeers, CJ; Vanden Bussche, G | 1 |
| Grevel, J; Richards, ML; Rosenbaum, JS; Sadée, W | 1 |
| Hug, CC | 1 |
| Herz, A; Schulz, R; Wüster, M | 1 |
| Pairet, M; Ruckebusch, Y | 1 |
| Leysen, JE; Van Gompel, P | 1 |
| Chen, YZ; Wang, CA; Yang, YH | 1 |
| Gähwiler, BH | 1 |
| Field, M; Kachur, JF; Miller, RJ | 1 |
| Grieb, P; Pokorski, M; Wideman, J | 1 |
| Lehtinen, AM | 1 |
| Herz, A; Shearman, GT | 1 |
| Chi, ZQ; Li, ZY; Ni, CH; Zhou, DH | 1 |
| Komatsu, T; Mori, K; Omatsu, Y; Osawa, M; Shingu, K; Urabe, N | 1 |
| Gioannini, T; Gorissen, H; Maryanoff, BE; Simon, EJ | 1 |
| Cools, AR; Megens, AA | 1 |
| Martin, WR; Wu, KM | 2 |
| Costa, T; Herz, A; Pollerberg, GE; Reid, LD; Shearman, GT | 1 |
| Kattau, RW; Leander, JD; Rathbun, RC | 1 |
| Laurent, S; Schmitt, H | 1 |
| Holford, NH; Rosenbaum, JS; Sadée, W | 1 |
| Aman, RA; Holford, NH; Richards, ML; Rosenbaum, JS; Sadée, W | 1 |
| Asahara, H; Asari, Y; Fujisawa, M; Fujita, T; Fukuda, M; Hanaoka, K; Hiranuma, H; Ikeda, K; Ikezono, E; Inada, Y; Innami, H; Kasuda, H; Kawashima, Y; Kiruta, Y; Kugimiya, T; Maruyama, H; Matsukura, M; Meguro, K; Morita, Y; Nanpo, T; Nishimura, N; Numata, K; Ogawa, K; Ogawa, R; Okada, K; Onodera, F; Shimizu, R; Tachibana, N; Watanabe, Y; Yasuda, K; Yogosawa, T; Yoshikawa, H | 1 |
| Komatsu, T; Mori, K; Osawa, M; Shingu, K; Tomemori, N | 1 |
| Cohen, MR; Dubois, M; Pickar, D | 1 |
| Deen, L; Helmers, JH; Noorduin, H; van Leeuwen, L; Zuurmond, WW | 1 |
| Hug, CC; McClain, DA | 1 |
| Castañeda, R; Lee, M; Velasco, F; Velasco, M | 1 |
| Laubie, M; Schmitt, H | 2 |
| Bigo, P; Franco, I; Manno, E; Matani, A | 1 |
| Askenasi, R; Fontaine, J; Lignian, H | 1 |
| Chaillet, P; Costentin, J; Marçais-Collado, H | 1 |
| Harp, JR; Rosenwasser, RH; Shupak, RC | 1 |
| Fyhrquist, F; Kivalo, I; Lehtinen, AM | 1 |
| Duncalf, D; Lesser, ML; Novakovic, M; Radnay, PA | 1 |
| Castañeda, R; Sánchez, R; Velasco, F; Velasco, M | 2 |
| Albani, G; Castiglioni, C; Mare, F; Serra, GC | 1 |
| Freye, E; Hartung, E | 2 |
| Chéramy, A; Chesselet, MF; Desban, M; Glowinski, J; Lubetzki, C; Reisine, TD | 1 |
| Essawi, MY; Portoghese, PS | 1 |
| Madura, JA; McCammon, RL; Stoelting, R | 1 |
| Carlsson, C; Magnusson, J; Pettersson, KI; Werner, O | 1 |
| Bloor, BC; Flacke, JW; Flacke, WE; Olewine, S | 1 |
| Rice, B | 1 |
| Collins, JG; Kitahata, LM; Matsumoto, M; Suzukawa, M; Yuge, O | 1 |
| Buchheit, WA; Harp, JR; Rossi, D; Shupak, RC; Stevenson-Smith, W | 1 |
| Niv, D; Whitwam, JG | 1 |
| Purdell-Lewis, JG | 1 |
| Barry, H; Krimmer, EC | 1 |
| Hagemeijer, F; Smalbraak, DW; Van Mechelen, R | 1 |
| Leander, JD; McCleary, PE | 1 |
| Tung, AS; Yaksh, TL | 1 |
| Folch Folch, A; Fontestad Fontestad, A; Maeso Velez, J; Sánchez Sánchez, J | 1 |
| Itohda, Y | 1 |
| Dhasmana, KM; Prakash, O; Saxena, PR | 1 |
| Colpaert, FC | 1 |
| Rich, JM | 1 |
| Bogaert, MG; Lefebvre, RA; Willems, JL | 1 |
| Blair, DM; McLeod, CA; Purdell-Lewis, JG | 1 |
| Neumark, J; Riegler, R | 1 |
| Devor, M; Sharav, Y; Tal, M | 1 |
| Hynes, M; Lal, H; Shearman, GT | 1 |
| Eerola, M; Eerola, R; Kaukinen, L; Kaukinen, S | 1 |
| Booth, NH; Keith, JC; Kemppainen, RJ; Wilson, RC | 1 |
| Freye, E; Gupta, BN | 1 |
| Gates, CC; Haigh, JC | 1 |
| Fujigaki, T; Makita, T; Nakamura, H; Shibata, O; Sumikawa, K; Tsujita, T | 1 |
| Alojado, ME; Kemmotsu, O; Ohta, Y | 1 |
| Carpenter, JW; Leith, DE; Shaw, ML | 1 |
| Abdullah, NM; Rolly, G; van Bastelaere, M | 1 |
| Shaham, Y | 1 |
| Hug, CC; Salmenperä, MT; Szlam, F | 1 |
| Dannals, RF; Frost, JJ; Lever, JR; Natarajan, TK; Ravert, HT; Tanada, S; Villemagne, VL; Wagner, HN; Wilson, AA | 1 |
| Shi, GG; Wei, DS; Xu, SF | 1 |
| Alvarez, J; Blanco, E; Blanco, J; Castro, A; Rodríguez, G | 1 |
| Barst, S; Boorin, MR; Crespi, P; Kreidstein, A; Lebowitz, P | 1 |
| Bravo, EL; Doss, DN; Estafanous, FG; Mekhail, NA | 1 |
| Hustveit, O | 2 |
| Fish, DJ; Keller, SM; Pelton, JJ | 1 |
| De Vries, TJ; Hogenboom, F; Mulder, AH; Schoffelmeer, AN | 1 |
| Chakrabarti, MK; Wang, C; Whitwam, JG | 1 |
| Atcheson, R; Lambert, DG; Rowbotham, DJ | 1 |
| Alvares, K; Grunberg, NE; Klein, LC; Shaham, Y | 1 |
| Davis, T; Duttaroy, A; Shah, S; Yoburn, BC | 1 |
| Iwanov, V; Karasawa, F; Moulds, RF | 1 |
| Lee, VC | 1 |
| Billings, B; Duttaroy, A; Yoburn, BC | 1 |
| Han, JS; Sun, YH; Zhang, ZW; Zhou, Y | 1 |
| Osifchin, E; Veng-Pedersen, P; Waters, SJ; Wilhelm, JA; Zakszewski, TB | 2 |
| Bouaziz, H; Eisenach, JC; Hood, DD; Tong, C; Yoon, Y | 1 |
| Bridges, MT; Grover, TE; Introna, RP; Pruett, JK; Yodlowski, EH | 1 |
| Davies, A; Gent, JP; Goodchild, CS; Guo, Z | 1 |
| Brill, T; Erhardt, W; Henke, J; Lendl, C; Matis, U; Otto, K; Roberts, U | 1 |
| Jaffe, RA; Rowe, MA | 1 |
| Cook, CD; Morgan, D; Negus, SS; Picker, MJ | 1 |
| Bengtsson, M; Kalman, S; Sörensen, J; Tropp, H | 1 |
| Beatty, MF; Chen, SW; Davies, MF; Loew, GH; Maguire, PA | 1 |
| Heidbreder, C; Lefevour, A; Shippenberg, TS | 1 |
| Freye, E; Neruda, B; Smith, OW | 1 |
| Angel, F; Chevalier, E; Dahl, SG; Friese, N; Junien, JL; Pascaud, X; Riviere, PJ | 1 |
| Mucha, RF | 1 |
| Coulais, Y; Francés, B; Goeldner, M; Guiraud, R; Hirth, C; Méjean-Galzi, A; Tafani, JA; Zajac, JM | 1 |
| Brandon, MJ; Geiger, MJ; Kearney, MM; Kent, V; Natale, A; Newby, KH; Wase, A | 1 |
| Hardwick, WE; King, WD; Palmisano, PA | 1 |
| Wishaw, K | 1 |
| Civelek, AC; Dannals, RF; Dixon, RB; Joh, T; Kao, PF; Kim, S; Ravert, HT; Villemagne, VL; Wagner, HN | 1 |
| McLoughlin, R; McQuillan, R | 1 |
| Cox, EH; Danhof, M; Kerbusch, T; Van der Graaf, PH | 1 |
| Briggs, SL; Rech, RH; Sawyer, DC | 1 |
| Brewer, C; Gastfriend, DR | 1 |
| Pennefather, S; Russell, G; Wang, J | 1 |
| Bläss, J; Sjöström, S | 1 |
| Virag, L; Vulliemoz, Y; Whittington, RA | 1 |
| Picker, MJ; Smith, MA | 1 |
| Brito, F; Gallegos, M; Jimenez, F; Velasco, AL; Velasco, F; Velasco, M | 1 |
| Baghdoyan, HA; Lydic, R; Mortazavi, S; Thompson, J | 1 |
| Essawi, MY | 1 |
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| Braunstein, SL; Carrillo, SA; Nolan, ML; Paone, D; Rivera, AV | 1 |
| Ellis, JD; Hobelmann, JG; Huhn, AS; Marks, KR; Smith, KE; Strickland, JC | 1 |
| Nelson, LS; Wightman, RS | 1 |
| Browne, K; Dayton, L; Konstantopoulos, A; Latkin, C; Uzzi, M; Yi, G | 1 |
| Barash, J; Cheng, C; Kofke, WA; Li, M; Liu, Q; Shen, Y; Sheng, Z; Xie, Z | 1 |
| Aldy, K; Brent, J; Calello, DP; Jefri, M; Krotulski, A; Logan, B; Manini, AF; Nguyen, TT; Walton, S; Wax, P | 1 |
| Ahmadi, SF; Bloom, S; Chaturbedi, A; Dahan, A; Eshleman, A; Florian, J; Han, X; Janowsky, A; Li, Z; Mann, J; Olofsen, E; Samieegohar, M; Strauss, DG; Swanson, T; Wolfrum, K; Zirkle, J | 1 |
| Callas, PW; Lynch, TV; Peterson, TD; Schlein, SM | 1 |
| Austin, EJ; Behrends, CN; Briggs, ES; Corcorran, MA; Des Jarlais, DC; Frank, ND; Frost, MC; Glick, SN; Healy, E; Juarez, AM; Kapadia, SN; LaKosky, PA; Perlman, DC; Prohaska, SM; Schackman, BR; Williams, EC | 1 |
| Albrecht, R; Hautz, WE; Josi, D; Jungwirth, A; Koppenberg, J; Moeckel, J; Pietsch, U; Strecke, S; Wenzel, V | 1 |
| Comer, SD; Foltin, RW; Nagaraj, N; Scranton, RE; Sykes, KA; Zale, S | 1 |
| Filteau, MR; Green, B; Kim, F; McBride, KA | 1 |
| Baekey, DM; Levitt, ES; Saunders, SE | 1 |
| Colella, MR; Farkas, A; Gooley, B; Weston, B | 1 |
| Anand, JP; Disney, A; Husbands, SM; Moore, SC; Olson, KM; Shafer, AM; Traynor, JR | 1 |
| Allen, ST; Grieb, SM; O'Rourke, A; Schneider, KE; Sherman, SG; White, RH; Winiker, AK | 1 |
| Ikeda, K; Ishikawa, T; Kasai, S; Rabozzi, R; Sasaki, K | 1 |
| Beardsley, PM; Elder, HJ; Varshneya, NB; Walentiny, DM | 1 |
| Bennett, AS; Felsher, M; Fletcher, S; Frank, D; Friedman, SR; Jaiswal, J; Jenkins, W; Muncan, B; Ompad, DC; Pho, MT; Townsend, T; Walters, SM | 1 |
| Chen, Y; Di, B; Lai, M; Li, F; Li, X; Qiu, Y; Shen, H; Wei, J; Xu, P | 1 |
| Baumann, MH; Chen, L; Goldberg, A; Le Rouzic, VP; Pan, YX; Shi, L; Sinha, A; Tsai, MM; Xie, B; Zhang, T | 1 |
| Azucar, D; Fernandez, P; Zambole, K | 1 |
| Curay, CM; Irwin, MR; Kiyatkin, EA | 1 |
| Beharie, N; Harocopos, A; Urmanche, A | 1 |
| Bell, LA; Hadland, SE | 1 |
| Ellis, CR; Liu, R; Mahinthichaichan, P; Shen, J; Stavitskaya, L; Vo, QN | 1 |
| Borys, S; Chaguturu, V; Chesin, M; Kline, A; Mattern, D; Steinberg, ML; Williams, JM | 1 |
| Beardsley, PM; Elder, HJ; Walentiny, DM | 1 |
| Adamowicz, P; Kurpeta, M; Wojcieszak, J; Zawilska, JB | 1 |
| Bosquez-Berger, T; Desmond, JA; Gudorf, JA; Kuntz, CP; Schlebach, JP; Straiker, A; VanNieuwenhze, MS | 1 |
| Ali, SA; Bedder, M; Harris, R; Shell, J | 1 |
| Baston, K; Bodofsky, E; Brangan, A; Buono, RJ; Dairo, O; Feigin, G; Ferraro, TN; Haroz, R; Heil, J; Heil, S; Issa, JJ; Jelinek, J; Kacinko, S; Kusic, DM; Madzo, J; Rafeq, R; Resch, A; Sabia, M; Salzman, M; Scheinfeldt, LB; Zajic, S | 1 |
| Leconte, CE; Sethi, R | 1 |
| Adams, A; Maloy, C; Warrick, BJ | 1 |
34 review(s) available for fentanyl and naloxone
| Article | Year |
|---|---|
The pharmacologic management of pain in children.
Topics: Analgesia, Epidural; Analgesics; Child; Child, Preschool; Codeine; Fentanyl; Humans; Infant; Meperidine; Methadone; Morphine; Naloxone; Narcotics; Pain | 1989 |
Drug discrimination studies.
Topics: Analgesics, Opioid; Animals; Columbidae; Discrimination, Psychological; Dose-Response Relationship, Drug; Fentanyl; Generalization, Stimulus; Macaca mulatta; Morphine; Nalorphine; Naloxone; Naltrexone; Pentazocine; Phenazocine; Phencyclidine; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1985 |
Evoked potentials as correlates of pain and pain relief in man.
Topics: Acupuncture Therapy; Analgesics; Brain; Dental Pulp; Evoked Potentials; Fentanyl; Humans; Naloxone; Nitrous Oxide; Nociceptors; Pain; Placebos | 1986 |
Neuroleptanalgesia for awake intubation and peroral endoscopies.
Topics: Anesthesia, Local; Atropine; Blood Pressure; Bronchoscopy; Diphenhydramine; Droperidol; Endoscopy; Esophagoscopy; Fentanyl; Gastric Lavage; Gastroscopy; Glucose; Humans; Inhalation; Intubation, Gastrointestinal; Meperidine; Naloxone; Neuroleptanalgesia; Pentobarbital; Preanesthetic Medication; Pulse; Respiration; Scopolamine; Tetracaine | 1973 |
The development of alfentanil.
Topics: Alfentanil; Analgesics, Opioid; Animals; Chemistry, Pharmaceutical; Drug Evaluation; Fentanyl; Humans; Kinetics; Mice; Naloxone; Rabbits; Rats; Reaction Time; Receptors, Opioid; Respiration; Therapeutic Equivalency; Time Factors | 1983 |
[Electrophysiological studies on the analgesic effects of general anesthetics (2)].
Topics: Analgesics; Anesthesia, General; Animals; Anterior Horn Cells; Cats; Decerebrate State; Fentanyl; Naloxone; Nitrous Oxide; Nociceptors; Spinal Cord | 1983 |
The role of the endogenous opioid system in the human stress response.
Topics: Endorphins; Fentanyl; Humans; Hydrocortisone; Intraoperative Period; Morphine; Naloxone; Pain; Pain, Postoperative; Physical Exertion; Postoperative Period; Stress, Physiological; Stress, Psychological; Surgical Procedures, Operative | 1983 |
[Alphadione anesthesia and "brief surgery"].
Topics: Alfaxalone Alfadolone Mixture; Ambulatory Surgical Procedures; Anesthesia; Fentanyl; Humans; Naloxone; Surgical Procedures, Operative | 1982 |
Measuring naloxone antagonism of discriminative opioid stimulus.
Topics: Animals; Columbidae; Conditioning, Psychological; Discrimination Learning; Fentanyl; Gerbillinae; Morphine; Naloxone; Narcotic Antagonists; Rats; Saimiri | 1982 |
PET imaging of the opioid receptor: the early years.
Topics: Animals; Diprenorphine; Fentanyl; Humans; Naloxone; Receptors, Opioid; Tomography, Emission-Computed | 2001 |
Sedation and analgesia for gastrointestinal endoscopy during pregnancy.
Topics: Analgesia; Analgesics, Opioid; Cholangiopancreatography, Endoscopic Retrograde; Conscious Sedation; Diazepam; Endoscopy, Gastrointestinal; Female; Fentanyl; Fetus; Flumazenil; Humans; Hypnotics and Sedatives; Ketamine; Lidocaine; Meperidine; Naloxone; Pregnancy; Propofol; Risk Assessment; Triage | 2006 |
[Spinal cord protection and opioids].
Topics: Analgesics, Opioid; Animals; Anterior Horn Cells; Dose-Response Relationship, Drug; Fentanyl; Glutamic Acid; Humans; Morphine; Naloxone; Nerve Degeneration; Paraparesis, Spastic; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord Ischemia; Thoracic Surgical Procedures | 2007 |
The occasional shoulder reduction.
Topics: Analgesics, Opioid; Anesthetics, Intravenous; Female; Fentanyl; Humans; Male; Manipulation, Orthopedic; Midazolam; Naloxone; Narcotic Antagonists; Physical Examination; Radiography; Shoulder Dislocation; Supine Position; Treatment Outcome | 2007 |
Review of Intranasally Administered Medications for Use in the Emergency Department.
Topics: Administration, Intranasal; Anesthetics, Dissociative; Anticonvulsants; Antidotes; Antipsychotic Agents; Dexmedetomidine; Emergency Service, Hospital; Fentanyl; Flumazenil; Haloperidol; Humans; Hydromorphone; Hypnotics and Sedatives; Ketamine; Lorazepam; Midazolam; Naloxone; Narcotic Antagonists; Narcotics | 2017 |
When to Pick the Nose: Out-of-Hospital and Emergency Department Intranasal Administration of Medications.
Topics: Administration, Intranasal; Analgesics, Opioid; Conscious Sedation; Dexmedetomidine; Drug Overdose; Emergency Service, Hospital; Fentanyl; Humans; Hypnotics and Sedatives; Ketamine; Midazolam; Naloxone; Patient Safety; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Treatment Outcome; Wounds and Injuries | 2017 |
Fentanyl, fentanyl analogs and novel synthetic opioids: A comprehensive review.
Topics: Analgesics, Opioid; Animals; Chromatography, Liquid; Designer Drugs; Fentanyl; Humans; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Tandem Mass Spectrometry | 2018 |
Abuse of fentanyl: An emerging problem to face.
Topics: Analgesics, Opioid; Dosage Forms; Drug Contamination; Drug Overdose; Drug Trafficking; Fentanyl; Humans; Illicit Drugs; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Transdermal Patch | 2018 |
The opioid crisis in Canada: a national perspective.
Topics: Age Factors; Canada; Drug Overdose; Emergency Medical Services; Fentanyl; Hospitalization; Humans; Illicit Drugs; Naloxone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Prescription Drugs; Risk Factors; Sex Factors; Vulnerable Populations | 2018 |
Carfentanil: a narrative review of its pharmacology and public health concerns.
Topics: Analgesics, Opioid; Animals; Fentanyl; Humans; Illicit Drugs; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Public Health; Veterinary Drugs | 2019 |
The role of take-home naloxone in the epidemic of opioid overdose involving illicitly manufactured fentanyl and its analogs.
Topics: Analgesics, Opioid; Animals; Drug Overdose; Fentanyl; Harm Reduction; Humans; Illicit Drugs; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; United States | 2019 |
Noradrenergic Mechanisms in Fentanyl-Mediated Rapid Death Explain Failure of Naloxone in the Opioid Crisis.
Topics: Adrenergic Neurons; Analgesics, Opioid; Drug Overdose; Fentanyl; Humans; Muscle Rigidity; Naloxone; Narcotic Antagonists; Opioid Epidemic; Respiratory Insufficiency; Time-to-Treatment | 2019 |
Naloxone dosing in the era of ultra-potent opioid overdoses: a systematic review.
Topics: Adult; Analgesics, Opioid; Child; Drug Overdose; Female; Fentanyl; Humans; Male; Naloxone; Narcotic Antagonists; Opiate Overdose | 2020 |
Impact of the Opioid Epidemic.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Humans; Naloxone; Opioid Epidemic | 2020 |
Carfentanil - from an animal anesthetic to a deadly illicit drug.
Topics: Analgesics, Opioid; Chromatography, Liquid; Drug Contamination; Drug Overdose; Fentanyl; Forensic Toxicology; Humans; Mass Spectrometry; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Respiratory Insufficiency | 2021 |
The anomalous pharmacology of fentanyl.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Humans; Naloxone; Narcotic Antagonists | 2023 |
Overdoses due to fentanyl and its analogues (F/FAs) push naloxone to the limit.
Topics: Diaphragm; Dose-Response Relationship, Drug; Fentanyl; Heroin; Humans; Laryngismus; Muscle Rigidity; Naloxone; Narcotic Antagonists; Opiate Overdose; Receptors, Opioid, mu; Thoracic Wall | 2021 |
New Designer Drugs.
Topics: Analgesics, Opioid; Buprenorphine; Cannabinoids; Designer Drugs; Drug Overdose; Fentanyl; Humans; Hypnotics and Sedatives; Illicit Drugs; Loperamide; Mitragyna; Naloxone; Narcotic Antagonists; Phenethylamines; Substance-Related Disorders | 2021 |
Harm Reduction in Health Care Settings.
Topics: Alcohol Drinking; Analgesics, Opioid; Behavior, Addictive; Central Nervous System Stimulants; Counseling; Delivery of Health Care; Drug Overdose; Fentanyl; Harm Reduction; Humans; Infection Control; Male; Naloxone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Pre-Exposure Prophylaxis; Substance-Related Disorders | 2022 |
Estimating naloxone need in the USA across fentanyl, heroin, and prescription opioid epidemics: a modelling study.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Heroin; Humans; Naloxone; Narcotic Antagonists; Opiate Overdose; Opioid Epidemic; Prescriptions; United States | 2022 |
Treatment of opioid overdose: current approaches and recent advances.
Topics: Analgesics, Opioid; Drug Overdose; Drug-Related Side Effects and Adverse Reactions; Fentanyl; Humans; Illicit Drugs; Naloxone; Narcotic Antagonists; Opiate Overdose; Retrospective Studies | 2022 |
Pharmacokinetic considerations for community-based dosing of nasal naloxone in opioid overdose in adults.
Topics: Adult; Analgesics, Opioid; Drug Overdose; Fentanyl; Humans; Naloxone; Narcotic Antagonists; Opiate Overdose | 2022 |
Unintentional overdoses: understanding the fentanyl landscape and reducing harm.
Topics: Adolescent; Analgesics, Opioid; Child; Drug Overdose; Fentanyl; Harm Reduction; Humans; Naloxone; Opioid-Related Disorders; Young Adult | 2023 |
Non-fentanyl new synthetic opioids - An update.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Humans; Illicit Drugs; Naloxone; Opioid-Related Disorders | 2023 |
Does occupational exposure to fentanyl cause illness? A systematic review.
Topics: Analgesics, Opioid; Chromatography, Liquid; Databases, Factual; Fentanyl; Humans; Naloxone; United States | 2023 |
66 trial(s) available for fentanyl and naloxone
| Article | Year |
|---|---|
[Clinical studies on the usefulness of naloxone after short lasting anaesthesias with narcotic analgesics (author's transl)].
Topics: Analgesics, Opioid; Anesthesia, General; Dose-Response Relationship, Drug; Female; Fentanyl; Flunitrazepam; Humans; Male; Naloxone; Pentazocine; Respiration Disorders | 1978 |
[Antagonistic effects of naloxone against morphinomimetic agents. Apropos of 10 cases in gynecologic surgery].
Topics: Adult; Clinical Trials as Topic; Consciousness; Drug Evaluation; Female; Fentanyl; Genital Diseases, Female; Humans; Hypoventilation; Middle Aged; Naloxone; Neuroleptanalgesia; Pain, Postoperative; Phenoperidine; Respiration | 1978 |
[Administration and dosage of flunitrazepam in combination with analgesics].
Topics: Adult; Aged; Analgesics; Anesthesia; Anti-Anxiety Agents; Blood Gas Analysis; Blood Pressure; Clinical Trials as Topic; Drug Combinations; Female; Fentanyl; Flunitrazepam; Humans; Male; Middle Aged; Naloxone; Pentazocine; Preanesthetic Medication; Pulse; Pupil; Respiration; Time Factors | 1978 |
[Insensitivity to pain: electrophysiological study of the nociceptive reflex. Influence of naloxone (author's transl)].
Topics: Adult; Endorphins; Female; Fentanyl; Humans; Male; Naloxone; Nociceptors; Pain Insensitivity, Congenital; Placebos; Receptors, Opioid; Reflex; Sensory Thresholds | 1978 |
Congenital insensitivity to pain and the "morphine-like" analgesic system.
Topics: Adult; Female; Fentanyl; Humans; Leg; Male; Naloxone; Nociceptors; Pain Insensitivity, Congenital; Receptors, Opioid; Reflex, Stretch; Sensory Thresholds | 1978 |
Naloxone: dose-dependent antagonism of respiratory depression by fentanyl in anaesthetized patients.
Topics: Adult; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Fentanyl; Humans; Middle Aged; Naloxone; Respiration | 1977 |
[Antidotism of fentanyl-N-alil noroxymorphone (naloxone) in analgesic anesthesia].
Topics: Acid-Base Equilibrium; Adult; Aged; Analgesia; Anesthesia, Intravenous; Clinical Trials as Topic; Drug Evaluation; Drug Interactions; Female; Fentanyl; Hemodynamics; Humans; Injections, Intravenous; Male; Middle Aged; Naloxone; Respiration | 1978 |
Antagonism of fentanyl with naloxone during N2O+O2+ halothane anaesthesia.
Topics: Adult; Aged; Anesthesia, Inhalation; Blood Pressure; Carbon Dioxide; Female; Fentanyl; Halothane; Humans; Male; Middle Aged; Naloxone; Nitrous Oxide; Pain, Postoperative; Pulse; Respiration; Tidal Volume | 1977 |
Naloxone as narcotic antagonist after balanced anaesthesia.
Topics: Adjuvants, Anesthesia; Adolescent; Adult; Aged; Anesthesia; Female; Fentanyl; Humans; Male; Middle Aged; Naloxone; Pain, Postoperative; Partial Pressure; Respiration | 1977 |
[Respiratory depression after fentanyl and antagonism by naloxone (author's transl)].
Topics: Adolescent; Adult; Aged; Anesthesia, General; Fentanyl; Flunitrazepam; Humans; Meperidine; Middle Aged; Naloxone; Pulmonary Ventilation; Respiration Disorders; Unconsciousness; Wakefulness | 1978 |
[Naloxone reversal of fentanyl anaesthesia in major vascular surgery (author's transl)].
Topics: Anesthesia, General; Aorta; Blood Gas Analysis; Dose-Response Relationship, Drug; Fentanyl; Humans; Naloxone; Respiration Disorders | 1978 |
[The effect of naloxone and levallorphane following fentanyl on the blood gases, EEG and psychodiagnostic tests (author's transl)].
Topics: Adult; Arrhythmias, Cardiac; Blood Gas Analysis; Double-Blind Method; Fentanyl; Humans; Levallorphan; Male; Naloxone; Psychological Tests; Respiration Disorders | 1978 |
The antagonist effect of naloxone hydrochloride after neuroleptanaesthesia during neurosurgery.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Evaluation; Female; Fentanyl; Humans; Male; Middle Aged; Naloxone; Nausea; Neuroleptanalgesia; Neurosurgery; Partial Pressure; Phenoperidine; Pulse; Respiration; Shivering; Tidal Volume; Vomiting | 1976 |
[A study on the action of naloxone (author's transl)].
Topics: Adult; Aged; Carbon Dioxide; Double-Blind Method; Drug Antagonism; Fentanyl; Humans; Middle Aged; Nalorphine; Naloxone; Oxygen; Partial Pressure; Placebos; Respiration | 1977 |
Systemic fentanyl enhances the spread of spinal analgesia produced by lignocaine.
Topics: Aged; Aged, 80 and over; Anesthesia, Spinal; Fentanyl; Humans; Injections, Intravenous; Injections, Spinal; Lidocaine; Male; Middle Aged; Naloxone; Prostatectomy; Time Factors | 1991 |
Nociceptive quality of the orbicularis oculi reflexes as evaluated by distinct opiate- and benzodiazepine-induced changes in man.
Topics: Adult; Blinking; Diazepam; Electric Stimulation; Electromyography; Fentanyl; Flumazenil; Humans; Naloxone; Nociceptors; Placebos | 1991 |
[Antagonism of flunitrazepam and fentanyl by flumazenil, naloxone or nalbuphine].
Topics: Adult; Double-Blind Method; Fentanyl; Flumazenil; Flunitrazepam; Humans; Middle Aged; Morphinans; Nalbuphine; Naloxone; Randomized Controlled Trials as Topic; Respiratory Insufficiency | 1990 |
Sufentanil anaesthesia for major surgery: the multicentre Canadian clinical trial.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics; Blood Pressure; Clinical Trials as Topic; Female; Fentanyl; Heart Rate; Humans; Hypotension; Male; Middle Aged; Multicenter Studies as Topic; Naloxone; Sufentanil | 1989 |
Comparison of morphine, meperidine, fentanyl, and sufentanil in balanced anesthesia: a double-blind study.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Anesthesia, General; Blood Pressure; Catecholamines; Double-Blind Method; Fentanyl; Heart Rate; Humans; Intraoperative Period; Meperidine; Middle Aged; Morphine; Naloxone; Random Allocation; Respiration; Sufentanil | 1985 |
Effect of naloxone infusion on analgesia and respiratory depression after epidural fentanyl.
Topics: Adult; Analgesia; Anesthesia, Epidural; Carbon Dioxide; Depression, Chemical; Dose-Response Relationship, Drug; Drug Evaluation; Drug Interactions; Fentanyl; Humans; Infusions, Intravenous; Lithotripsy; Middle Aged; Naloxone; Random Allocation; Respiration; Time Factors | 1988 |
[Effects of intravenous naloxone on the secondary effects and analgesia after epidural injection of fentanyl].
Topics: Adult; Aged; Analgesia; Carbon Dioxide; Double-Blind Method; Female; Fentanyl; Humans; Injections, Epidural; Injections, Intravenous; Male; Middle Aged; Naloxone; Postoperative Period; Respiration | 1987 |
Comparison between high-dose sufentanil-oxygen and high-dose fentanyl-oxygen for neuroanaesthesia.
Topics: Adolescent; Adult; Anesthesia, Intravenous; Anesthetics; Brain; Female; Fentanyl; Hemodynamics; Humans; Intubation, Intratracheal; Male; Middle Aged; Naloxone; Oxygen; Postoperative Period; Sufentanil | 1985 |
Buprenorphine antagonism of ventilatory depression following fentanyl anaesthesia.
Topics: Adult; Aged; Anesthesia, General; Buprenorphine; Double-Blind Method; Female; Fentanyl; Humans; Middle Aged; Naloxone; Prospective Studies; Respiratory Insufficiency | 1988 |
[Nalbuphine following fentanyl. Postoperative analgesia].
Topics: Abdomen; Adolescent; Adult; Aged; Anesthesia, Inhalation; Arousal; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Fentanyl; Humans; Middle Aged; Morphinans; Nalbuphine; Naloxone; Pain, Postoperative | 1987 |
Antagonism of postoperative opioid-induced respiratory depression: nalbuphine versus naloxone.
Topics: Adult; Anesthesia Recovery Period; Double-Blind Method; Female; Fentanyl; Humans; Male; Middle Aged; Morphinans; Nalbuphine; Naloxone; Random Allocation; Respiration | 1987 |
Naloxone, fentanyl, and diazepam modify plasma beta-endorphin levels during surgery.
Topics: Diazepam; Double-Blind Method; Drug Evaluation; Endorphins; Fentanyl; Humans; Intraoperative Period; Molar, Third; Naloxone; Pain; Premedication; Tooth, Impacted | 1986 |
A comparison of alfentanil and fentanyl in short operations with special reference to their duration of action and postoperative respiratory depression.
Topics: Adolescent; Adult; Aged; Alfentanil; Analgesics, Opioid; Anesthesia; Blood Pressure; Depression, Chemical; Female; Fentanyl; Heart Rate; Humans; Middle Aged; Naloxone; Respiration; Time Factors | 1981 |
[A multi-clinical study on the antagonizing effects of naloxone on postoperative respiratory depression after neuroleptanalgesia].
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Female; Fentanyl; Humans; Male; Middle Aged; Naloxone; Neuroleptanalgesia; Postoperative Complications; Respiratory Insufficiency | 1983 |
Effect of fentanyl and naloxone on the P300 auditory potential.
Topics: Adult; Electroencephalography; Evoked Potentials, Auditory; Female; Fentanyl; Humans; Male; Naloxone; Pain; Sensory Thresholds | 1984 |
Common bile duct pressure changes after fentanyl, morphine, meperidine, butorphanol, and naloxone.
Topics: Anesthesia; Butorphanol; Cholecystectomy; Common Bile Duct; Fentanyl; Humans; Jaundice; Manometry; Meperidine; Monitoring, Physiologic; Morphinans; Morphine; Naloxone | 1984 |
Effect of fentanyl and naloxone on human somatic and auditory-evoked potential components.
Topics: Adult; Anesthesia; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials, Auditory; Evoked Potentials, Somatosensory; Female; Fentanyl; Humans; Male; Naloxone; Neuroleptanalgesia | 1984 |
Studies on fentanyl-supplemented anaesthesia: effect on naloxone on the circulation and respiration.
Topics: Adolescent; Adult; Aged; Anesthesia, Inhalation; Blood Circulation; Female; Fentanyl; Humans; Intermittent Positive-Pressure Ventilation; Male; Middle Aged; Naloxone; Nitrous Oxide; Oxygen; Respiration | 1980 |
Fentanyl-etomidate anesthesia for cardioversion.
Topics: Adult; Aged; Anesthesia; Clinical Trials as Topic; Diazepam; Electric Countershock; Etomidate; Female; Fentanyl; Humans; Imidazoles; Male; Middle Aged; Naloxone | 1982 |
Studies in fentanyl-supplemented anaesthesia: awareness and effect of naloxone on early post-operative recovery.
Topics: Anesthesia; Awareness; Cognition; Fentanyl; Humans; Memory; Mental Recall; Naloxone; Recovery Room | 1981 |
[Physostigmine and reversal of anticholinergic effects of neurolept-anaesthesia (author's transl)].
Topics: Atropine; Consciousness; Depression, Chemical; Droperidol; Drug Therapy, Combination; Female; Fentanyl; Genital Diseases, Female; Humans; Naloxone; Neuroleptanalgesia; Parasympatholytics; Physostigmine | 1981 |
The antagonistic effect of pentazocine on fentanyl induced respiratory depression compared with nalorphine and naloxone.
Topics: Adult; Anesthesia, General; Female; Fentanyl; Humans; Middle Aged; Nalorphine; Naloxone; Pentazocine; Respiratory Distress Syndrome | 1981 |
Postoperative analgesia and plasma levels after transdermal fentanyl for orthopedic surgery: double-blind comparison with placebo.
Topics: Administration, Cutaneous; Adult; Analgesia; Anesthesia, Inhalation; Anesthesia, Intravenous; Blood Pressure; Bone and Bones; Double-Blind Method; Female; Fentanyl; Humans; Male; Middle Aged; Morphine; Naloxone; Oxygen; Pain Measurement; Pain, Postoperative; Placebos; Respiration | 1995 |
Can a pharmacological pain analysis be used in the assessment of chronic low back pain?
Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Female; Fentanyl; Humans; Lidocaine; Low Back Pain; Male; Morphine; Naloxone; Narcotic Antagonists; Nerve Block; Pain Measurement; Single-Blind Method | 1996 |
Longer occupancy of opioid receptors by nalmefene compared to naloxone as measured in vivo by a dual-detector system.
Topics: Adult; Analgesics, Opioid; Brain; Carbon Radioisotopes; Cross-Over Studies; Female; Fentanyl; Humans; Male; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Time Factors; Tomography, Emission-Computed | 1997 |
Low-dose naloxone in the treatment of urinary retention during extradural fentanyl causes excessive reversal of analgesia.
Topics: Analgesics, Opioid; Fentanyl; Humans; Naloxone; Narcotic Antagonists; Urinary Retention | 1998 |
Postoperative analgesia with epidural bupivacaine and low-dose fentanyl--a comparison of two concentrations.
Topics: Aged; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Buprenorphine; Colon; Cough; Fentanyl; Follow-Up Studies; Humans; Infusion Pumps; Injections, Intravenous; Leg; Middle Aged; Muscle Weakness; Naloxone; Narcotic Antagonists; Pain Measurement; Pain, Postoperative; Rectum; Respiration | 1998 |
Analgesic effects of peripherally administered opioids in clinical models of acute and chronic inflammation.
Topics: Acute Disease; Adult; Analgesics, Opioid; Chronic Disease; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fentanyl; Humans; Injections; Male; Mepivacaine; Morphine; Naloxone; Pain Measurement; Pain, Postoperative; Periodontitis; Time Factors; Tooth Extraction; Toothache; Treatment Outcome | 2001 |
Enhanced temporal summation of second pain and its central modulation in fibromyalgia patients.
Topics: Adult; Analgesics, Opioid; Cold Temperature; Female; Fentanyl; Fibromyalgia; Hot Temperature; Humans; Hyperalgesia; Middle Aged; Naloxone; Narcotic Antagonists; Nociceptors; Pain; Placebos; Psychophysics | 2002 |
PET imaging of human cardiac opioid receptors.
Topics: Aged; Carbon Radioisotopes; Feasibility Studies; Female; Fentanyl; Heart; Humans; Indoles; Lung; Male; Middle Aged; Morphinans; Muscle, Skeletal; Myocardium; Naloxone; Radiopharmaceuticals; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Reproducibility of Results; Sensitivity and Specificity; Tissue Distribution; Tomography, Emission-Computed | 2002 |
Enteral naloxone reduces gastric tube reflux and frequency of pneumonia in critical care patients during opioid analgesia.
Topics: Administration, Oral; Adult; Analgesics, Opioid; Critical Care; Cross Infection; Defecation; Double-Blind Method; Enteral Nutrition; Female; Fentanyl; Gastric Emptying; Gastrointestinal Motility; Humans; Infection Control; Intubation, Gastrointestinal; Male; Middle Aged; Naloxone; Narcotic Antagonists; Pneumonia, Aspiration; Prospective Studies; Respiration, Artificial | 2003 |
The site of action of epidural fentanyl in humans: the difference between infusion and bolus administration.
Topics: Adult; Algorithms; Analgesia, Epidural; Analgesics, Opioid; Area Under Curve; Cross-Over Studies; Double-Blind Method; Electric Stimulation; Female; Fentanyl; Hot Temperature; Humans; Infusion Pumps; Infusions, Parenteral; Injections; Male; Naloxone; Narcotic Antagonists; Pain; Pain Measurement | 2003 |
Prophylactic epidural naloxone reduces the incidence and severity of neuraxial fentanyl-induced pruritus during labour analgesia in primiparous parturients.
Topics: Adult; Analgesia, Obstetrical; Analgesics, Opioid; Double-Blind Method; Female; Fentanyl; Heart Rate, Fetal; Humans; Incidence; Injections, Epidural; Naloxone; Narcotic Antagonists; Pregnancy; Prospective Studies; Pruritus; Severity of Illness Index | 2003 |
Intrathecal fentanyl-induced pruritus during labour: the effect of prophylactic ondansetron.
Topics: Adult; Analgesia, Obstetrical; Analgesics, Opioid; Double-Blind Method; Female; Fentanyl; Humans; Injections, Intravenous; Injections, Spinal; Naloxone; Narcotic Antagonists; Ondansetron; Pain; Postoperative Nausea and Vomiting; Pregnancy; Pruritus; Serotonin Antagonists | 2004 |
[Effect of enteral naloxone on the incidence of gastritis and esophagitis in mechanically ventilated patients].
Topics: Adult; Analgesics, Opioid; Double-Blind Method; Esophagitis; Female; Fentanyl; Gastric Mucosa; Gastritis; Gastrointestinal Motility; Humans; Intubation, Gastrointestinal; Male; Middle Aged; Naloxone; Narcotic Antagonists; Respiration, Artificial | 2004 |
A multicenter randomized controlled trial comparing patient-controlled epidural with intravenous analgesia for pain relief in labor.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthetics, Local; Apgar Score; Bupivacaine; Canada; Cesarean Section; Dose-Response Relationship, Drug; Double-Blind Method; Dystocia; Female; Fentanyl; Humans; Infant, Newborn; Injections, Intravenous; Naloxone; Narcotic Antagonists; Patient Compliance; Pregnancy; Treatment Outcome | 2004 |
Mu-opioid self-administration vs passive administration in heroin abusers produces differential EEG activation.
Topics: Adult; Analgesics, Opioid; Double-Blind Method; Electroencephalography; Female; Fentanyl; Heroin Dependence; Humans; Male; Methadone; Naloxone; Narcotic Antagonists; Narcotics; Psychiatric Status Rating Scales; Pupil; Receptors, Opioid, mu; Self Administration | 2005 |
Opioid craving and seeking behavior in physically dependent volunteers: effects of acute withdrawal and drug reinforcement opportunity.
Topics: Adult; Conditioning, Operant; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fentanyl; Heroin Dependence; Humans; Male; Methadone; Naloxone; Narcotic Antagonists; Narcotics; Psychiatric Status Rating Scales; Reinforcement, Psychology; Reward; Substance Withdrawal Syndrome; Surveys and Questionnaires | 2005 |
Opioid-induced respiratory effects: new data on buprenorphine.
Topics: Analgesics, Opioid; Apnea; Buprenorphine; Dose-Response Relationship, Drug; Double-Blind Method; Fentanyl; Humans; Naloxone; Narcotic Antagonists; Neoplasms; Pain; Respiratory Insufficiency | 2006 |
Effect of low-dose naloxone infusion on fentanyl requirements in critically ill children.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Conscious Sedation; Critical Illness; Double-Blind Method; Female; Fentanyl; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Infusions, Intravenous; Intensive Care Units, Pediatric; Male; Midazolam; Naloxone; Narcotic Antagonists; Respiration, Artificial; Substance Withdrawal Syndrome | 2008 |
An ultra-low dose of naloxone added to lidocaine or lidocaine-fentanyl mixture prolongs axillary brachial plexus blockade.
Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Axilla; Brachial Plexus; Double-Blind Method; Drug Combinations; Elective Surgical Procedures; Female; Fentanyl; Forearm; Humans; Lidocaine; Male; Middle Aged; Naloxone; Narcotic Antagonists; Nerve Block; Pain Measurement; Pain Threshold; Pain, Postoperative; Postoperative Nausea and Vomiting; Prospective Studies; Pruritus; Recovery of Function; Time Factors; Treatment Outcome; Young Adult | 2009 |
Evaluation of the single- and multiple-dose pharmacokinetics of fentanyl buccal soluble film in normal healthy volunteers.
Topics: Administration, Buccal; Adult; Analgesics, Opioid; Analysis of Variance; Area Under Curve; Chromatography, High Pressure Liquid; Electrocardiography; Female; Fentanyl; Half-Life; Humans; Male; Naloxone; Narcotic Antagonists; Nonlinear Dynamics; Oximetry; Reproducibility of Results; Tandem Mass Spectrometry; Young Adult | 2010 |
Naloxone reversal of an overdose of a novel, long-acting transdermal fentanyl solution in laboratory Beagles.
Topics: Administration, Topical; Analgesics, Opioid; Animals; Delayed-Action Preparations; Dog Diseases; Dogs; Drug Overdose; Fentanyl; Naloxone; Narcotic Antagonists; Solutions; Time Factors | 2012 |
Naloxone versus metoclopramide for the treatment of established postoperative nausea and vomiting in patients following general anesthesia with fentanyl supplementation--pilot study.
Topics: Adult; Aged; Analgesics, Opioid; Anesthesia, General; Antiemetics; Female; Fentanyl; Humans; Male; Metoclopramide; Middle Aged; Naloxone; Narcotic Antagonists; Pilot Projects; Postoperative Nausea and Vomiting; Prospective Studies | 2012 |
Antiemetic effect of naloxone in combination with dexamethasone and droperidol in patients undergoing laparoscopic gynecological surgery.
Topics: Adult; Antiemetics; Dexamethasone; Droperidol; Drug Combinations; Female; Fentanyl; Gynecologic Surgical Procedures; Humans; Laparoscopy; Naloxone; Postoperative Nausea and Vomiting | 2013 |
Pharmacokinetic interaction of intravenous fentanyl with ketoconazole.
Topics: Administration, Intravenous; Adult; Analgesics, Opioid; Chromatography, Liquid; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Female; Fentanyl; Healthy Volunteers; Humans; Ketoconazole; Male; Midazolam; Middle Aged; Naloxone; Prospective Studies; Tandem Mass Spectrometry; Young Adult | 2015 |
Naloxone added to bupivacaine or bupivacaine-fentanyl prolongs motor and sensory block during supraclavicular brachial plexus blockade: a randomized clinical trial.
Topics: Adjuvants, Anesthesia; Adult; Anesthetics, Local; Brachial Plexus; Brachial Plexus Block; Bupivacaine; Drug Synergism; Drug Therapy, Combination; Female; Fentanyl; Humans; Male; Motor Activity; Naloxone; Narcotic Antagonists; Pain, Postoperative; Time Factors | 2015 |
Injection anaesthesia with fentanyl-midazolam-medetomidine in adult female mice: importance of antagonization and perioperative care.
Topics: Analgesics; Anesthetics, Combined; Animals; Body Temperature; Female; Fentanyl; Flumazenil; Heart Rate; Imidazoles; Injections, Intraperitoneal; Medetomidine; Mice; Mice, Inbred C57BL; Midazolam; Naloxone; Narcotic Antagonists; Neurotransmitter Agents; Perioperative Care | 2016 |
Effect of naloxone on intravenous fentanyl patient-controlled analgesia after laparoscopic cholecystectomy.
Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Intravenous; Antiemetics; Cholecystectomy, Laparoscopic; Drug Therapy, Combination; Female; Fentanyl; Humans; Indoles; Male; Middle Aged; Naloxone; Narcotic Antagonists; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Tropisetron | 2016 |
Intranasal naloxone rapidly occupies brain mu-opioid receptors in human subjects.
Topics: Administration, Intranasal; Adult; Analgesics, Opioid; Brain; Double-Blind Method; Fentanyl; Healthy Volunteers; Humans; Male; Naloxone; Narcotic Antagonists; Positron-Emission Tomography; Receptors, Opioid, mu; Young Adult | 2019 |
Naloxone-Induced Withdrawal in Individuals With and Without Fentanyl-Positive Urine Samples.
Topics: Adult; Female; Fentanyl; Heroin Dependence; Humans; Male; Middle Aged; Naloxone; Narcotic Antagonists; Pilot Projects; Retrospective Studies; Severity of Illness Index; Substance Withdrawal Syndrome; Young Adult | 2020 |
Spatial and neighborhood-level correlates of lay naloxone reversal events and service availability.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Heroin; Humans; Naloxone; Narcotic Antagonists; United States | 2022 |
547 other study(ies) available for fentanyl and naloxone
| Article | Year |
|---|---|
New 4-(heteroanilido)piperidines, structurally related to the pure opioid agonist fentanyl, with agonist and/or antagonist properties.
Topics: Analgesics, Opioid; Animals; Chemical Phenomena; Chemistry; Drug Evaluation, Preclinical; Fentanyl; In Vitro Techniques; Male; Mice; Morphine; Narcotic Antagonists; Rabbits; Rats; Rats, Inbred Strains; Receptors, Opioid; Structure-Activity Relationship | 1989 |
Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors.
Topics: Analgesics; Animals; Binding Sites; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Ligands; PC12 Cells; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Software | 1994 |
Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications.
Topics: Animals; Aorta, Thoracic; Cocaine; Cyclic AMP; Electric Stimulation; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Opioid-Related Disorders; Rats; Receptors, Dopamine; Receptors, Opioid; Receptors, Serotonin; Substance-Related Disorders | 1998 |
From hit to lead. Combining two complementary methods for focused library design. Application to mu opiate ligands.
Topics: Animals; Cerebral Cortex; Combinatorial Chemistry Techniques; Humans; Imidazoles; In Vitro Techniques; Ligands; Magnetic Resonance Spectroscopy; Radioligand Assay; Rats; Receptors, Opioid, mu; Solubility; Spiro Compounds; Structure-Activity Relationship | 2001 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Discriminative stimulus properties of fentanyl and morphine: tolerance and dependence.
Topics: Analgesics, Opioid; Animals; Discrimination, Psychological; Drug Tolerance; Fentanyl; Generalization, Psychological; Humans; Male; Morphine; Naloxone; Rats; Reaction Time; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors | 1976 |
The effects of anesthetic drugs and disease on the chemical regulation of ventilation.
Topics: Anesthetics; Anti-Anxiety Agents; Autonomic Nervous System; Barbiturates; Benzodiazepines; Carbon Dioxide; Fentanyl; Halothane; Humans; Hyperthyroidism; Hypoxia; Lung Diseases, Obstructive; Meperidine; Methoxyflurane; Morphine; Naloxone; Neuromuscular Blocking Agents; Neuromuscular Diseases; Obesity; Pulmonary Edema; Pulmonary Fibrosis; Respiration; Scoliosis | 1977 |
[The use of morphine and morphine antagonists in the postoperative geriatric patient].
Topics: Aged; Cardiovascular System; Drug Evaluation; Fentanyl; Humans; Middle Aged; Morphine; Naloxone; Pain, Postoperative | 1977 |
A study of naloxone and doxapram as agents for the reversal of neuroleptanalgesic respiratory depression in the conscious rabbit.
Topics: Animals; Carbon Dioxide; Depression, Chemical; Doxapram; Droperidol; Fentanyl; Hydrogen-Ion Concentration; Lethal Dose 50; Male; Naloxone; Neuroleptanalgesia; Rabbits; Respiration; Respiratory Function Tests; Time Factors | 1978 |
The opiate receptor: a model explaining structure-activity relationships of opiate agonists and antagonists.
Topics: Allosteric Regulation; Dextropropoxyphene; Fentanyl; Methadone; Models, Biological; Models, Molecular; Molecular Conformation; Morphine; Nalorphine; Naloxone; Narcotics; Pentazocine; Phenazocine; Protein Conformation; Receptors, Opioid; Structure-Activity Relationship | 1976 |
[Action of delta 9 tetrahydrocannabinol on the central cardiovascular regulation : mechanism and localization].
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cannabis; Cardiovascular System; Cats; Clonidine; Dogs; Dronabinol; Electric Stimulation; Evoked Potentials; Fentanyl; Heart Rate; Hypothalamus; Medulla Oblongata; Morphine Derivatives; Nalorphine; Naloxone; Sciatic Nerve; Splanchnic Nerves; Spleen | 1975 |
[Naloxone as a drug for improving anesthesia results in children].
Topics: Adolescent; Anesthesia, Intravenous; Child; Child, Preschool; Depression, Chemical; Female; Fentanyl; Humans; Hypercapnia; Infant; Male; Naloxone; Pulmonary Gas Exchange; Respiration; Respiratory Insufficiency | 1979 |
Thrombophlebitis after intravenous use of anesthesia and sedation: its incidence and natural history.
Topics: Adolescent; Adult; Anesthesia, Dental; Anesthesia, Intravenous; Child; Diazepam; Drug Interactions; Female; Fentanyl; Humans; Male; Methohexital; Middle Aged; Naloxone; Needles; Thrombophlebitis | 1979 |
Restlessness and shivering after naloxone reversal of fentanyl-supplemented anaesthesia.
Topics: Adult; Aged; Akathisia, Drug-Induced; Anesthesia, General; Body Temperature; Female; Fentanyl; Homeostasis; Humans; Hypercapnia; Male; Middle Aged; Naloxone; Nitrous Oxide; Respiration; Shivering; Thiopental | 1979 |
Perfusion of the fourth cerebral ventricle with fentanyl induces naloxone-reversible bradycardia, hypotension, and EEG synchronisation in conscious dogs.
Topics: Animals; Blood Pressure; Cortical Synchronization; Dogs; Electroencephalography; Fentanyl; Heart Rate; Injections, Intraventricular; Naloxone | 1979 |
Circulatory pattern and duration of action of naloxone in dogs with and without opioid pretreatment.
Topics: Animals; Blood Pressure; Carbon Dioxide; Cardiac Output; Coronary Circulation; Dogs; Female; Fentanyl; Half-Life; Heart Rate; Hemodynamics; Infusions, Parenteral; Male; Naloxone; Oxygen; Oxygen Consumption; Partial Pressure; Stroke Volume; Vascular Resistance | 1979 |
Althesin for neuroanaesthesia.
Topics: Adolescent; Adult; Aged; Alfaxalone Alfadolone Mixture; Anesthesia, Intravenous; Brain; Child; Female; Fentanyl; Humans; Infusions, Parenteral; Male; Middle Aged; Naloxone | 1979 |
Evaluation of fentanyl citrate, etorphine hydrochloride, and naloxone hydrochloride in captive polar bears.
Topics: Anesthesia; Animals; Carnivora; Etorphine; Female; Fentanyl; Immobilization; Male; Morphinans; Naloxone; Ursidae | 1979 |
Gastric relaxation by morphine, apomorphine and fentanyl in the conscious dog.
Topics: Animals; Apomorphine; Benzimidazoles; Dogs; Domperidone; Fentanyl; Haloperidol; Morphine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naloxone; Piperidines; Stomach; Vomiting | 1979 |
Electroencephalographic study of pentazocine and buprenorphine.
Topics: Animals; Brain; Buprenorphine; Cats; Electroencephalography; Fentanyl; Humans; Morphinans; Morphine; Naloxone; Narcotics; Nociceptors; Pentazocine; Rabbits; Time Factors | 1979 |
Comparing the effects of anileridine, alphaprodine and fentanyl on schedule-controlled responding by pigeons.
Topics: Alphaprodine; Animals; Behavior, Animal; Columbidae; Conditioning, Operant; Dose-Response Relationship, Drug; Fentanyl; Isonipecotic Acids; Male; Methadone; Morphine; Naloxone; Reinforcement Schedule | 1978 |
[The effect of the morphine antagonist naloxone on the effect of fentanyl].
Topics: Arousal; Electroencephalography; Fentanyl; Humans; Hypnotics and Sedatives; Levallorphan; Motor Activity; Naloxone; Time Factors; Wakefulness | 1978 |
Clinical experiences with naloxone in neuroradiology.
Topics: Adjuvants, Anesthesia; Benperidol; Blood Pressure; Cerebral Angiography; Drug Evaluation; Fentanyl; Heart Rate; Humans; Naloxone; Neostigmine; Neuroleptanalgesia; Pancuronium; Respiration | 1977 |
Influence of fentanyl on the chronotropic response of isolated rabbit atria to cholinergic and adrenergic stimulation.
Topics: Acetylcholine; Animals; Electric Stimulation; Female; Fentanyl; Heart Rate; In Vitro Techniques; Levallorphan; Male; Morphine; Myocardial Contraction; Naloxone; Norepinephrine; Parasympathetic Nervous System; Rabbits; Sympathetic Nervous System | 1978 |
[Naloxone--a clinical study on dosage (author's transl)].
Topics: Adolescent; Adult; Anesthesia, Inhalation; Child; Female; Fentanyl; Humans; Male; Middle Aged; Naloxone; Neuroleptanalgesia; Opium; Respiratory Function Tests; Respiratory Insufficiency | 1978 |
Effect of naloxone reversal on CO2 output, oxygen uptake and cardiac index during recovery from fentanyl-supplemented anaesthesia.
Topics: Adult; Aged; Anesthesia; Carbon Dioxide; Cardiac Output; Female; Fentanyl; Humans; Male; Middle Aged; Naloxone; Oxygen Consumption; Partial Pressure; Respiration | 1978 |
Naloxone reversal of choledochoduodenal sphincter spasm associated with narcotic administration.
Topics: Adult; Ampulla of Vater; Cholangiography; Female; Fentanyl; Humans; Morphine; Naloxone; Spasm; Sphincter of Oddi | 1978 |
Reversal of fentanyl-induced narcotic depression with naloxone following general anaesthesia.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Drug Evaluation; Female; Fentanyl; Humans; Male; Middle Aged; Naloxone; Partial Pressure; Respiration Disorders; Venous Pressure | 1978 |
Immobilisation of free-ranging wild animals using a new drug.
Topics: Animal Population Groups; Animals; Animals, Wild; Artiodactyla; Azaperone; Elephants; Fentanyl; Immobilization; Morphinans; Naloxone; Narcotic Antagonists; Perissodactyla; Xylazine | 1978 |
The effects of intravenous fentanyl, morphine and naloxone on nociceptive responses of neurones in the rat caudal medulla.
Topics: Animals; Electric Stimulation; Electroencephalography; Fentanyl; Male; Medulla Oblongata; Morphine; Naloxone; Neurons; Pain; Rats; Reticular Formation; Time Factors | 1978 |
Fallow deer immobilisation with fentanyl and a neuroleptic.
Topics: Animals; Azaperone; Deer; Female; Fentanyl; Immobilization; Injections, Intramuscular; Injections, Intravenous; Levallorphan; Male; Naloxone; Thiazines; Time Factors; Xylazine | 1977 |
[Clinical evaluation of naloxone].
Topics: Adult; Aged; Consciousness; Female; Fentanyl; Humans; Male; Middle Aged; Naloxone; Respiration | 1977 |
Anesthetic management for direct approach to carotid-cavernous fistula: case report.
Topics: Adult; Anesthesia; Arteriovenous Fistula; Atropine; Carotid Artery Diseases; Cavernous Sinus; Dexamethasone; Diazepam; Droperidol; Female; Fentanyl; Heart Arrest; Humans; Hypothermia, Induced; Naloxone; Neostigmine; Neuroleptanalgesia; Pancuronium; Preanesthetic Medication; Thiopental | 1977 |
Postanaesthetic use of naloxone hydrochloride after moderate doses of fentanyl.
Topics: Adolescent; Adult; Aged; Anesthesia, Inhalation; Carbon Dioxide; Drug Evaluation; Female; Fentanyl; Humans; Male; Middle Aged; Naloxone; Neuroleptanalgesia; Partial Pressure; Postoperative Care; Respiration; Time Factors | 1976 |
Fentanyl and apomorphine: asymmetrical generalization of discriminative stimulus properties.
Topics: Animals; Apomorphine; Cues; Discrimination, Psychological; Dose-Response Relationship, Drug; Fentanyl; Generalization, Psychological; Haloperidol; Male; Naloxone; Rats; Receptors, Dopamine | 1976 |
Effects of fentanyl and droperidol on the dopamine metabolism of the rat striatum.
Topics: Animals; Catalepsy; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Droperidol; Fentanyl; Haloperidol; Homovanillic Acid; Humans; Male; Naloxone; Rats | 1976 |
Actions of opiates upon single unit activity in the cortex of naive and tolerant rats.
Topics: Acetylcholine; Action Potentials; Animals; Dextrorphan; Drug Tolerance; Evoked Potentials; Fentanyl; Glutamates; Humans; Levorphanol; Male; Morphine; Morphine Dependence; Naloxone; Narcotics; Neurons; Rats; Somatosensory Cortex | 1976 |
A comparison in mice of naloxone and nalorphine as antagonists to neuroleptanalgesic drugs.
Topics: Animals; Depression, Chemical; Dose-Response Relationship, Drug; Droperidol; Drug Synergism; Female; Fentanyl; Male; Mice; Nalorphine; Naloxone; Neuroleptanalgesia; Reaction Time; Respiration; Time Factors | 1976 |
[High doses of fentanyl as the sole anaesthetic agent and naloxone as its antagonist (author's transl)].
Topics: Adolescent; Adult; Aged; Analgesia; Autonomic Nervous System; Child; Child, Preschool; Female; Fentanyl; Genital Diseases, Female; Humans; Hypertension; Hypotension; Male; Maxilla; Middle Aged; Naloxone; Nausea; Neurosurgery; Tachycardia; Vomiting | 1975 |
Localization of the central sympatho-inhibitory effect of a narcotic analgesic agent, fentanyl, in cats.
Topics: Animals; Blood Pressure; Cats; Depression, Chemical; Electric Stimulation; Evoked Potentials; Female; Fentanyl; Heart Rate; Hypothalamus; Male; Medulla Oblongata; Nalorphine; Naloxone; Spinal Cord; Splanchnic Nerves; Sympathetic Nervous System | 1975 |
An appraisal of naloxone hydrochloride as a narcotic antagonist in the capture and release of wild herbivores.
Topics: Animals; Antelopes; Artiodactyla; Buffaloes; Elephants; Etorphine; Fentanyl; Male; Mammals; Naloxone; Perissodactyla; Swine | 1975 |
Opioid agonists binding and responses in SH-SY5Y cells.
Topics: Alprostadil; Analgesics; Cyclic AMP; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Fentanyl; GTP Phosphohydrolases; Humans; Meperidine; Morphinans; Naloxone; Narcotics; Oxymorphone; Receptors, Opioid; Receptors, Opioid, mu; Tumor Cells, Cultured | 1992 |
Opioid enhancement of evoked [Met5]enkephalin release requires activation of cholinergic receptors: possible involvement of intracellular calcium.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Atropine; Calcimycin; Calcium; Colforsin; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Evoked Potentials; Fentanyl; Guinea Pigs; Hexamethonium Compounds; In Vitro Techniques; Myenteric Plexus; Naloxone; Pyrrolidines; Receptors, Muscarinic; Receptors, Opioid; Sufentanil | 1992 |
[Effects of microiontophoretically applied OMF and U-50488 on spontaneous discharges of respiration related units in the region of nucleus of solitary tract of rat].
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Depression, Chemical; Electrophysiology; Female; Fentanyl; Iontophoresis; Male; Medulla Oblongata; Naloxone; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid; Respiration | 1992 |
Use of medetomidine-fentanyl-fluanisone combinations in the badger.
Topics: Adrenergic alpha-Antagonists; Animals; Animals, Wild; Butyrophenones; Carnivora; Female; Fentanyl; Hypnotics and Sedatives; Imidazoles; Male; Medetomidine; Naloxone | 1992 |
[Development of continuous monitoring of spontaneous respiration in the postoperative phase. 2. Cutaneous oxygen and carbon dioxide partial pressures following i.v. bolus application of fentanyl, buprenorphine, naloxone and amiphenazole in healthy adult s
Topics: Adult; Buprenorphine; Carbon Dioxide; Central Nervous System Stimulants; Drug Combinations; Female; Fentanyl; Humans; Injections, Intravenous; Male; Monitoring, Physiologic; Naloxone; Oxygen; Partial Pressure; Postoperative Period; Reference Values; Respiration; Skin; Thiazoles; Time Factors | 1992 |
Effect of fentanyl on cardiac automaticity and conduction: direct or mediated action?
Topics: Animals; Arrhythmias, Cardiac; Denervation; Dogs; Electrocardiography; Fentanyl; Heart; Heart Block; Heart Conduction System; Heart Transplantation; Hemodynamics; Models, Cardiovascular; Naloxone; Transplantation, Heterotopic | 1992 |
Effects of ohmefentanyl on CA1 field potentials in rat hippocampus slices.
Topics: Analgesics; Animals; Evoked Potentials; Fentanyl; Hippocampus; Male; Morphine; Naloxone; Rats; Rats, Wistar | 1992 |
Relative effects of intrathecal administration of fentanyl and midazolam on A delta and C fibre reflexes.
Topics: Anesthesia, Spinal; Animals; Dogs; Electric Stimulation; Fentanyl; Flumazenil; Kidney; Midazolam; Naloxone; Nerve Fibers; Nerve Fibers, Myelinated; Reflex; Sympathetic Nervous System; Tibial Nerve | 1992 |
Effects of opioids on vasoresponsiveness of porcine coronary artery.
Topics: Acetylcholine; Animals; Arteries; Coronary Vessels; Endothelium, Vascular; Female; Fentanyl; Histamine; In Vitro Techniques; Kinetics; Male; Morphine; Muscle Contraction; Muscle, Smooth, Vascular; Naloxone; Narcotics; Norepinephrine; Sufentanil; Swine; Vasoconstrictor Agents | 1992 |
Apparent pA2 value of naltrexone is not changed in rats following continuous exposure to morphine or naloxone.
Topics: Analysis of Variance; Animals; Body Weight; Dose-Response Relationship, Drug; Drug Interactions; Fentanyl; Male; Morphine; Naloxone; Naltrexone; Pain Measurement; Rats; Rats, Inbred Strains | 1992 |
Paradoxical opiate specific paralytic effects of high doses of intracerebroventricular etorphine and fentanyl in rats.
Topics: Animals; Etorphine; Fentanyl; Injections, Intraventricular; Injections, Spinal; Male; Naloxone; Paralysis; Rats; Rats, Inbred Strains; Receptors, Opioid | 1991 |
Effects of intravenous mu and kappa opioid receptor agonists on sensory responses of convergent neurones in the dorsal horn of spinalized rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Benzodiazepines; Fentanyl; Hot Temperature; Male; Morphine; Naloxone; Neurons, Afferent; Nociceptors; Physical Stimulation; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord | 1991 |
Evaluation of receptor mechanism mediating fentanyl analgesia and toxicity.
Topics: Analgesics; Animals; Brain; Drug Tolerance; Fentanyl; Lethal Dose 50; Male; Mice; Morphine; Naloxone; Naltrexone; Receptors, Opioid | 1991 |
Opiate receptor antagonists for delusions of parasitosis.
Topics: Delusions; Female; Fentanyl; Fluspirilene; Humans; Middle Aged; Myiasis; Naloxone; Naltrexone; Narcotic Antagonists | 1991 |
Reversal by naloxone of spinal antinociceptive effects of fentanyl, ketocyclazocine and midazolam.
Topics: Analgesia, Epidural; Animals; Catheters, Indwelling; Dose-Response Relationship, Drug; Drug Tolerance; Electric Stimulation; Ethylketocyclazocine; Fentanyl; Flumazenil; Injections, Spinal; Lumbar Vertebrae; Male; Midazolam; Naloxone; Nociceptors; Pain; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Opioid; Sensory Thresholds | 1991 |
Spinally mediated antinociception following intrathecal chlordiazepoxide--further evidence for a benzodiazepine spinal analgesic effect.
Topics: Analgesia, Epidural; Animals; Catheters, Indwelling; Chlordiazepoxide; Dose-Response Relationship, Drug; Electric Stimulation; Fentanyl; Flumazenil; Injections, Spinal; Male; Naloxone; Nociceptors; Pain; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sensory Thresholds | 1991 |
The actions of fentanyl to inhibit drug-induced emesis.
Topics: Animals; Antiemetics; Apomorphine; Autoradiography; Brain Stem; Cisplatin; Copper; Copper Sulfate; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; Fentanyl; Ferrets; Male; Morphine; Naloxone; Receptors, Opioid; Receptors, Opioid, mu; Vomiting | 1991 |
The effects of sham and full spinalization on the systemic potency of mu- and kappa-opioids on spinal nociceptive reflexes in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Decerebrate State; Dose-Response Relationship, Drug; Fentanyl; Male; Morphine; Motor Neurons; Naloxone; Nociceptors; Pain; Physical Stimulation; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reflex; Spinal Cord | 1991 |
Opioids can produce a concentration-dependent naloxone-reversible enhancement of inhibition of evoked enkephalin release.
Topics: Analgesics; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Dynorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Fentanyl; Guinea Pigs; In Vitro Techniques; Myenteric Plexus; Naloxone; Narcotics; Parasympatholytics; Sufentanil; Thionucleotides; Virulence Factors, Bordetella | 1990 |
Ethanol and opiate decrease the axonal transport of substance-P like immunoreactive material in rat vagus-nerves.
Topics: Analgesics; Analgesics, Opioid; Animals; Axons; Benzimidazoles; Biological Transport; Choice Behavior; Drinking; Ethanol; Fentanyl; Ligation; Male; Naloxone; Narcotics; Rats; Rats, Inbred Strains; Substance P; Time Factors; Vagus Nerve | 1990 |
[Use of an opioid antagonist naloxone and the agonist-antagonist nalbuphine during the awakening period to eliminate depressive effects of fentanyl].
Topics: Adolescent; Adult; Aged; Anesthesia Recovery Period; Anesthesia, General; Child; Child, Preschool; Depression, Chemical; Digestive System Diseases; Fentanyl; Heart Diseases; Humans; Middle Aged; Nalbuphine; Naloxone; Postoperative Care; Respiratory Insufficiency; Wounds and Injuries | 1991 |
[Relationship between central beta-endorphins and serotonin systems in mechanism of hypoxic ventilatory regulation].
Topics: Animals; beta-Endorphin; Fentanyl; Hypoxia; Injections, Intraventricular; Male; Naloxone; Rabbits; Respiration; Serotonin | 1991 |
Interactions between the discriminative stimulus effects of mu and kappa opioid agonists in the squirrel monkey.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Behavior, Animal; Buprenorphine; Drug Interactions; Fentanyl; Learning; Male; Morphinans; Naloxone; Narcotics; Pentobarbital; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Saimiri | 1991 |
Differential cross-tolerance to mu and kappa opioid agonists in morphine-tolerant rats responding under a schedule of food presentation.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzomorphans; Chlorpromazine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Tolerance; Ethylketocyclazocine; Fentanyl; Food; Male; Methadone; Morphine; Naloxone; Narcotics; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reinforcement Schedule | 1991 |
Imipramine-fentanyl antinociception in a rabbit tooth pulp model.
Topics: Analgesics; Animals; Carbon Dioxide; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Electric Stimulation; Female; Fentanyl; Imipramine; Injections, Intravenous; Kinetics; Male; Morphine; Naloxone; Nociceptors; Rabbits; Respiration | 1991 |
Opioid modulation of the micturition reflex at the level of the pontine micturition center.
Topics: Animals; Cats; Decerebrate State; Dogs; Endorphins; Fentanyl; Naloxone; Pons; Reflex; Urinary Bladder; Urination; Urodynamics | 1991 |
China White epidemic: an eastern United States emergency department experience.
Topics: Adult; Analgesics; Disease Outbreaks; Drug Overdose; Emergencies; Female; Fentanyl; Humans; Male; Naloxone; Pennsylvania; Poisoning; Retrospective Studies | 1991 |
Effect of anaesthetics on the release of beta-endorphin-immunoreactivity in rat plasma.
Topics: Analgesics; Anesthetics; Animals; beta-Endorphin; Butyrophenones; Drug Combinations; Ether; Fentanyl; Male; Naloxone; Pentobarbital; Radioimmunoassay; Rats; Rats, Inbred Strains; Urethane | 1991 |
[Reversal of high-dose fentanyl anesthesia by naloxone: analysis of factors attenuating respiratory and hemodynamic responses to naloxone].
Topics: Anesthesia Recovery Period; Fentanyl; Hemodynamics; Humans; Naloxone; Respiration | 1991 |
Delayed subarachnoid migration of an epidural catheter.
Topics: Aged; Analgesia, Epidural; Anesthesia, Epidural; Blood Pressure; Bupivacaine; Catheterization; Female; Fentanyl; Humans; Naloxone; Subarachnoid Space | 1990 |
Immobilization of gray wolves (Canis lupus) with sufentanil citrate.
Topics: Anesthetics; Animals; Arousal; Carnivora; Etorphine; Female; Fentanyl; Immobilization; Male; Naloxone; Sufentanil; Xylazine; Yohimbine | 1990 |
Prolonged mu- and delta-receptor occupancy may result in naloxone-reversible respiratory depression and naloxone-irreversible antinociception.
Topics: Alfentanil; Animals; Depression, Chemical; Dogs; Fentanyl; Naloxone; Nociceptors; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Respiration; Thebaine | 1990 |
Discriminative stimulus properties of U50,488 and morphine: effects of training dose on stimulus substitution patterns produced by mu and kappa opioid agonists.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Benzomorphans; Cyclazocine; Discrimination Learning; Dose-Response Relationship, Drug; Ethylketocyclazocine; Fentanyl; Male; Methadone; Morphine; Naloxone; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1990 |
Synthesis and pharmacological evaluation of a series of new 3-methyl-1,4-disubstituted-piperidine analgesics.
Topics: Analgesics; Animals; Binding, Competitive; Chemical Phenomena; Chemistry, Physical; Dose-Response Relationship, Drug; Drug Design; Fentanyl; Mice; Morphine; Naloxone; Piperidines; Rats; Receptors, Opioid; Tetrazoles; Time Factors | 1990 |
Potent and long lasting antinociceptive effects after injection of low doses of a mu-opioid receptor agonist, fentanyl, into the brachial plexus sheath of the rat.
Topics: Animals; Brachial Plexus; Fentanyl; Forelimb; Injections; Injections, Intravenous; Male; Naloxone; Nociceptors; Pain Measurement; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Sodium Chloride | 1990 |
Multiple opioid receptors mediate the respiratory depressant effects of fentanyl-like drugs in the rat.
Topics: Alfentanil; Anesthesia; Animals; Apnea; Blood Gas Analysis; Fentanyl; Hemodynamics; In Vitro Techniques; Injections, Intraventricular; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Respiration; Sufentanil; Vagotomy | 1990 |
[Reversal of high-dose fentanyl anesthesia by naloxone].
Topics: Adult; Aged; Anesthesia Recovery Period; Fentanyl; Humans; Middle Aged; Naloxone | 1990 |
Narcotic reversal in hypercapnic dogs: comparison of naloxone and nalbuphine.
Topics: Analysis of Variance; Animals; Blood Pressure; Dogs; Epinephrine; Fentanyl; Heart Rate; Hypercapnia; Morphinans; Nalbuphine; Naloxone; Norepinephrine | 1990 |
Narcotic analgesic, its antagonists and common bile duct pressure.
Topics: Adult; Aged; Aminophylline; Anesthesia, Intravenous; Atropine; Cholecystectomy; Common Bile Duct; Fentanyl; Humans; Hydrostatic Pressure; Middle Aged; Naloxone; Sphincter of Oddi | 1990 |
Opioid control of the function of primary afferent substance P fibres.
Topics: Afferent Pathways; Animals; Electric Stimulation; Enkephalins; Fentanyl; In Vitro Techniques; Naloxone; Perfusion; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Vasodilation | 1985 |
Sublingual absorption of selected opioid analgesics.
Topics: Administration, Sublingual; Adult; Analgesics, Opioid; Analysis of Variance; Biological Availability; Buprenorphine; Fentanyl; Heroin; Humans; Hydromorphone; Levorphanol; Methadone; Morphine; Mouth; Naloxone; Oxycodone; Time Factors | 1988 |
Anesthetic interactions of midazolam and fentanyl: is there acute tolerance to the opioid?
Topics: Anesthesia, Inhalation; Animals; Dogs; Drug Interactions; Enflurane; Fentanyl; Flumazenil; Male; Midazolam; Naloxone; Pulmonary Alveoli; Respiration | 1989 |
CO2 levels during opioid reversal with naloxone.
Topics: Animals; Carbon Dioxide; Dogs; Fentanyl; Humans; Naloxone; Respiration | 1989 |
Effects of midazolam on fentanyl antinociception and respiration in a rabbit model.
Topics: Analgesics; Animals; Carbon Dioxide; Drug Combinations; Electric Stimulation; Female; Fentanyl; Infusions, Intravenous; Male; Midazolam; Naloxone; Rabbits; Respiration; Respiratory Insufficiency | 1989 |
Clinical pharmacology of sedatives and opioid analgesics, Part II.
Topics: Anesthesia, Dental; Fentanyl; Humans; Meperidine; Naloxone; Pain, Postoperative; Sufentanil | 1989 |
Multicompartmental analysis of [11C]-carfentanil binding to opiate receptors in humans measured by positron emission tomography.
Topics: Adult; Brain; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Fentanyl; Frontal Lobe; Humans; Kinetics; Male; Naloxone; Occipital Lobe; Receptors, Opioid; Thalamus; Tomography, Emission-Computed | 1989 |
Magnitude of opioid dependence after continuous intrathecal infusion of mu- and delta-selective opioids in the rat.
Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Fentanyl; Injections, Spinal; Male; Morphine; Naloxone; Narcotics; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Substance Withdrawal Syndrome; Substance-Related Disorders; Sufentanil; Time Factors | 1989 |
Mu opiate receptors are selectively labelled by [3H]carfentanil in human and rat brain.
Topics: Animals; Binding, Competitive; Brain Chemistry; Cerebral Cortex; Diencephalon; Fentanyl; Haloperidol; Humans; In Vitro Techniques; Kinetics; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu | 1989 |
Mu-opioid component of the ethylketocyclazocine (EKC) discriminative stimulus in the rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Cyclazocine; Discrimination, Psychological; Dose-Response Relationship, Drug; Ethylketocyclazocine; Fentanyl; Male; Morphine; Naloxone; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, mu | 1989 |
Discriminative stimulus effects of mu and kappa opioids in the pigeon: analysis of the effects of full and partial mu and kappa agonists.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzodiazepines; Benzomorphans; Columbidae; Cyclazocine; Discrimination Learning; Ethylketocyclazocine; Fentanyl; Morphinans; Naloxone; Narcotics; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1989 |
Negative chronotropic actions of sufentanil and vecuronium in chronically instrumented dogs pretreated with propranolol and/or diltiazem.
Topics: Analgesics; Animals; Diltiazem; Dogs; Drug Interactions; Electrocardiography; Fentanyl; Heart Rate; Hemodynamics; Naloxone; Propranolol; Sufentanil; Vecuronium Bromide | 1989 |
Rats self-administer sufentanil in aerosol form.
Topics: Aerosols; Analgesics, Opioid; Animals; Conditioning, Operant; Fentanyl; Male; Naloxone; Rats; Rats, Inbred Strains; Reinforcement Schedule; Self Administration; Sufentanil | 1989 |
Opioids can enhance and inhibit the electrically evoked release of methionine-enkephalin.
Topics: Action Potentials; Animals; Colforsin; Cyclic AMP; Dynorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Fentanyl; Guinea Pigs; Myenteric Plexus; Naloxone; Sufentanil | 1989 |
Comparison of histamine release in human skin mast cells induced by morphine, fentanyl, and oxymorphone.
Topics: Cell Membrane; Dose-Response Relationship, Drug; Fentanyl; Histamine; Histamine Release; Humans; Hydromorphone; Leukocytes; Mast Cells; Morphine; Naloxone; Oxymorphone; Receptors, Opioid; Skin | 1985 |
Chloroacryloyl amides and alpha-methylenelactones from naltrexone, oxymorphone and fentanyl.
Topics: Acrylates; Animals; Binding Sites; Brain; Chemical Phenomena; Chemistry; Fentanyl; Hydromorphone; In Vitro Techniques; Membranes; Naloxone; Naltrexone; Oxymorphone; Rats; Stereoisomerism | 1985 |
Fentanyl overdose in a neonate: use of naloxone infusion.
Topics: Drug Overdose; Fentanyl; Humans; Infant, Newborn; Male; Medication Errors; Naloxone | 1989 |
Fentanyl-induced airway hyperreactivity in the guinea pig.
Topics: Animals; Atropine; Bronchial Provocation Tests; Drug Interactions; Fentanyl; Guinea Pigs; Histamine; Male; Muscle Tonus; Naloxone; Propranolol; Respiration; Serotonin | 1989 |
Opioid peptides modulate the organization of vimentin filaments, phagocytic activity, and expression of surface molecules in monocytes.
Topics: Antigens, Surface; Cytoskeleton; Endorphins; Fentanyl; Flow Cytometry; Humans; Intermediate Filaments; Monocytes; Naloxone; Phagocytosis; Vimentin | 1989 |
Fentanyl decreases catecholamine metabolism measured by in vivo voltammetry in the rat locus coeruleus.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Catecholamines; Catechols; Clonidine; Fentanyl; Hydrogen-Ion Concentration; Locus Coeruleus; Male; Naloxone; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1989 |
The effect of fentanyl anesthesia and intrathecal naloxone on neurologic outcome following spinal cord injury in the rat.
Topics: Anesthesia Recovery Period; Animals; Catheterization; Dose-Response Relationship, Drug; Drug Interactions; Fentanyl; Injections, Spinal; Isoflurane; Male; Naloxone; Nervous System; Nitrous Oxide; Rats; Rats, Inbred Strains; Spinal Cord Injuries; Subarachnoid Space; Time Factors | 1989 |
Effect of mu- and kappa-opioid agonists on the electroconvulsive seizure threshold in mice and antagonism by naloxone and MR 2266.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzeneacetamides; Benzodiazepines; Benzomorphans; Electroshock; Fentanyl; Male; Mice; Morphinans; Morphine; Nalbuphine; Naloxone; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Seizures | 1988 |
Long-term blockade of mu-opioid receptors suggests a role in control of ingestive behaviour, body weight and core temperature in the rat.
Topics: Animals; Benzomorphans; Body Temperature Regulation; Body Weight; Circadian Rhythm; Drinking Behavior; Feeding Behavior; Fentanyl; Male; Naloxone; Pain; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Sufentanil | 1988 |
Sympathetic stimulating effects of sufentanil in the cat are mediated centrally.
Topics: Adrenal Medulla; Adrenergic Fibers; Animals; Blood Pressure; Brain; Cardiovascular Physiological Phenomena; Cardiovascular System; Catecholamines; Cats; Enkephalin, Methionine; Fentanyl; Heart Rate; Injections, Intravenous; Naloxone; Receptors, Opioid; Sufentanil | 1988 |
Opiate receptors in brain labelled in vivo with [3H]lofentanil.
Topics: Analgesics, Opioid; Animals; Binding, Competitive; Brain; Fentanyl; Kinetics; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Subcellular Fractions | 1985 |
Antagonism of fentanyl and alfentanil by intravenous plus subcutaneous naloxone. Pattern of ventilatory depression after a short procedure.
Topics: Aged; Alfentanil; Analgesics, Opioid; Depression, Chemical; Fentanyl; Humans; Injections, Intravenous; Injections, Subcutaneous; Middle Aged; Naloxone; Postoperative Period; Respiration | 1985 |
Contractor responses of the isolated colon of the mouse to morphine and some opioid peptides.
Topics: Acetylcholine; Alfentanil; Animals; Colon; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, Methionine; Fentanyl; Gastrointestinal Motility; Indomethacin; Mice; Morphine; Naloxone; Peptide Fragments; Tetrodotoxin; Time Factors | 1985 |
An analysis of naltrexone and naloxone's possible agonistic actions in the dog.
Topics: Analgesics, Opioid; Animals; Cyclazocine; Dogs; Drug Synergism; Electroencephalography; Ethylketocyclazocine; Evoked Potentials; Female; Fentanyl; Morphine; Naloxone; Naltrexone; Reaction Time; Reflex; Reflex, Pupillary | 1985 |
Epidural injections of bupivacaine, morphine, fentanyl, lofentanil, and DADL in chronically implanted rats: a pharmacologic and pathologic study.
Topics: Analgesia; Analgesics, Opioid; Animals; Behavior, Animal; Bupivacaine; Catheterization; Catheters, Indwelling; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Epidural Space; Fentanyl; Male; Morphine; Motor Activity; Naloxone; Rats; Rats, Inbred Strains; Reaction Time; Time Factors | 1986 |
Studies of the pharmacology and pathology of intrathecally administered 4-anilinopiperidine analogues and morphine in the rat and cat.
Topics: Alfentanil; Analgesia; Analgesics, Opioid; Animals; Catheterization; Cats; Dose-Response Relationship, Drug; Drug Tolerance; Fentanyl; Humans; Injections, Spinal; Morphine; Motor Activity; Naloxone; Rats; Spinal Cord; Sufentanil; Time Factors | 1986 |
Comparison of the antinociceptive action of mu and delta opioid receptor ligands in the periaqueductal gray matter, medial and paramedial ventral medulla in the rat as studied by the microinjection technique.
Topics: Analgesics, Opioid; Animals; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Fentanyl; Male; Medulla Oblongata; Morphine; Naloxone; Oligopeptides; Periaqueductal Gray; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sufentanil | 1986 |
Pharmacokinetics and pharmacodynamics of alfentanil infusions during general anesthesia.
Topics: Adult; Age Factors; Alfentanil; Analgesics, Opioid; Anesthesia, General; Blood Pressure; Dose-Response Relationship, Drug; Female; Fentanyl; Heart Rate; Humans; Infusions, Parenteral; Kinetics; Male; Middle Aged; Naloxone | 1986 |
Gastrointestinal transit following intrathecal or subcutaneous narcotic analgesics.
Topics: Alfentanil; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Female; Fentanyl; Gastrointestinal Motility; Injections, Epidural; Injections, Subcutaneous; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Sufentanil | 1987 |
Stimulation of opiate receptors in the dorsal pontine tegmentum inhibits reflex contraction of the urinary bladder.
Topics: Animals; Enkephalin, Methionine; Fentanyl; Glutamates; Glutamic Acid; Microinjections; Muscle Contraction; Naloxone; Narcotic Antagonists; Pressure; Rats; Receptors, Opioid; Reflex; Tegmentum Mesencephali; Urinary Bladder | 1988 |
Differential effects on gastrointestinal activity after intrathecal morphine, sufentanil and alfentanil in rats.
Topics: Alfentanil; Analgesics, Opioid; Animals; Female; Fentanyl; Gastrointestinal Motility; Injections, Spinal; Injections, Subcutaneous; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Sufentanil | 1987 |
A new method for determination of in vivo pA2 using infusions of naloxone to steady-state blood concentrations.
Topics: Alfentanil; Analgesics, Opioid; Animals; Binding, Competitive; Chromatography, High Pressure Liquid; Drug Antagonism; Fentanyl; Half-Life; Infusions, Intravenous; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Respiration; Time Factors | 1988 |
Mu-, delta- and kappa-opioid receptor-mediated inhibition of neurotransmitter release and adenylate cyclase activity in rat brain slices: studies with fentanyl isothiocyanate.
Topics: Acetylcholine; Adenylyl Cyclases; Animals; Brain; Dopamine; Fentanyl; In Vitro Techniques; Isothiocyanates; Male; Naloxone; Neurotransmitter Agents; Norepinephrine; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1988 |
Interaction of fentanyl and pentobarbital on peripheral and cerebral hemodynamics in newborn lambs.
Topics: Animals; Animals, Newborn; Brain; Cardiac Output; Cerebrovascular Circulation; Drug Interactions; Fentanyl; Hemodynamics; Naloxone; Oxygen Consumption; Pentobarbital; Sheep | 1989 |
Acute respiratory arrest and rigidity after anesthesia with sufentanil: a case report.
Topics: Acute Disease; Adult; Anesthesia, General; Anesthetics; Apnea; Coma; Fentanyl; Humans; Male; Muscle Rigidity; Naloxone; Postoperative Complications; Respiratory Insufficiency; Sufentanil; Time Factors | 1985 |
On the cholinergic component of action of meptazinol.
Topics: Acetylcholine; Animals; Azepines; Diaphragm; Dose-Response Relationship, Drug; Fentanyl; Ileum; Male; Meptazinol; Morphine; Muscle Contraction; Naloxone; Rats; Rats, Inbred Strains | 1986 |
Selective effect of sufentanil on group III (A delta) and group IV (C) somatosympathetic reflexes.
Topics: Animals; Blood Pressure; Dogs; Fentanyl; Heart Rate; Naloxone; Nervous System; Reaction Time; Reflex; Sufentanil; Sympathetic Nervous System | 1986 |
Antidromic vasodilatation in the rat hindpaw measured by laser Doppler flowmetry: pharmacological modulation.
Topics: Adrenergic Fibers; Animals; Capsaicin; Cimetidine; Electric Stimulation; Enkephalin, Methionine; Female; Fentanyl; Hindlimb; Lasers; Male; Naloxone; Pyrilamine; Rats; Regional Blood Flow; Rheology; Skin; Vasodilation | 1987 |
Opioid dependence in the guinea-pig myenteric plexus is controlled by non-tolerant and tolerant opioid receptors.
Topics: Animals; Drug Tolerance; Fentanyl; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Muscle Contraction; Myenteric Plexus; Naloxone; Narcotics; Opioid-Related Disorders; Receptors, Opioid; Substance Withdrawal Syndrome | 1985 |
Effect of mu and kappa opioid receptor agonists on rat plasma corticosterone levels.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzodiazepines; Benzomorphans; Corticosterone; Dose-Response Relationship, Drug; Fentanyl; Male; Morphine; Naloxone; Naltrexone; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1985 |
Spinal sufentanil effects on spinal pain-transmission neurons in cats.
Topics: Animals; Cats; Drug Interactions; Female; Fentanyl; Male; Naloxone; Neurons; Pain; Spinal Cord; Sufentanil; Synaptic Transmission | 1986 |
3H-diprenorphine is selective for mu opiate receptors in vivo.
Topics: Animals; Binding, Competitive; Corpus Striatum; Diprenorphine; Fentanyl; Kinetics; Male; Mice; Mice, Inbred ICR; Morphinans; Naloxone; Receptors, Opioid; Receptors, Opioid, mu; Thalamus; Tritium | 1986 |
Simplified detection system for neuroreceptor studies in the human brain.
Topics: Binding, Competitive; Brain; Calibration; Carbon Radioisotopes; Electrons; Equipment Design; Fentanyl; Humans; Naloxone; Radioligand Assay; Receptors, Opioid; Scintillation Counting | 1986 |
Prompt arousal from fentanyl-droperidol-pentobarbital anesthesia in dogs: a preliminary study.
Topics: 4-Aminopyridine; Aminopyridines; Anesthesia; Anesthetics; Animals; Arousal; Dogs; Doxapram; Droperidol; Drug Combinations; Fentanyl; Naloxone; Pentobarbital; Yohimbine | 1986 |
The modification by systemic morphine of the responses of serotonergic and non-serotonergic neurons in nucleus raphe magnus to heating the tail.
Topics: Animals; Fentanyl; Hot Temperature; Male; Morphine; Naloxone; Neural Conduction; Neurons; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Synaptic Transmission; Tail | 1986 |
'Catatonia' produced by alfentanil is reversed by methylnaloxonium microinjections into the brain.
Topics: Alfentanil; Animals; Brain; Catatonia; Fentanyl; Male; Motor Activity; Naloxone; Quaternary Ammonium Compounds; Rats; Rats, Inbred Strains; Receptors, Opioid | 1986 |
A dose-ratio comparison of mu and kappa agonists in formalin and thermal pain.
Topics: Analgesia; Animals; Benzomorphans; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Fentanyl; Formaldehyde; Hot Temperature; Male; Naloxone; Pain; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sufentanil | 1986 |
TRH-induced antinociception: interaction with the opioid systems?
Topics: Analgesia; Animals; Brain; Cyclazocine; Endorphins; Ethylketocyclazocine; Fentanyl; Male; Mice; Morphine; Naloxone; Receptors, Opioid; Thyrotropin-Releasing Hormone | 1987 |
The role of the nucleus raphe pontis and the caudate nucleus in alfentanil rigidity in the rat.
Topics: Alfentanil; Animals; Catatonia; Caudate Nucleus; Electromyography; Fentanyl; Male; Muscle Rigidity; Naloxone; Pons; Quaternary Ammonium Compounds; Raphe Nuclei; Rats; Rats, Inbred Strains | 1986 |
Comparison of the cardiac effects of naloxone administration after fentanyl and halothane anesthesia.
Topics: Adult; Anesthesia, General; Carbon Dioxide; Female; Fentanyl; Halothane; Hemodynamics; Humans; Male; Middle Aged; Naloxone; Respiration | 1986 |
Agonist and antagonist effects of prototype opiate drugs in fentanyl dose-dose discrimination.
Topics: Animals; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Fentanyl; Generalization, Stimulus; Male; Morphine; Naloxone; Narcotics; Rats; Rats, Inbred Strains | 1986 |
Clinical experience with alfentanil infusion.
Topics: Alfentanil; Analgesics; Anesthesia Recovery Period; Anesthesia, Inhalation; Bradycardia; Drug Administration Schedule; Fentanyl; Hemodynamics; Humans; Infusions, Intravenous; Naloxone; Postoperative Period | 1987 |
Localization of brainstem sites which mediate alfentanil-induced muscle rigidity in the rat.
Topics: Alfentanil; Animals; Brain Stem; Fentanyl; Muscle Rigidity; Naloxone; Quaternary Ammonium Compounds; Raphe Nuclei; Rats; Rats, Inbred Strains | 1988 |
Cardiovascular effects of fentanyl reversal by naloxone at varying arterial carbon dioxide tensions in dogs.
Topics: Animals; Blood Pressure; Carbon Dioxide; Cardiac Output; Dogs; Epinephrine; Fentanyl; Heart Rate; Hypercapnia; Naloxone; Norepinephrine; Vascular Resistance | 1988 |
Pharmacodynamics of alfentanil as a supplement to nitrous oxide anaesthesia in the elderly patient.
Topics: Adjuvants, Anesthesia; Aged; Aged, 80 and over; Alfentanil; Anesthesia, Inhalation; Female; Fentanyl; Humans; Male; Naloxone; Nitrous Oxide; Probability | 1988 |
Delayed respiratory depression after alfentanil.
Topics: Adolescent; Adult; Alfentanil; Fentanyl; Humans; Male; Naloxone; Respiration Disorders; Respiration, Artificial; Spinal Fusion | 1988 |
Diagnostic epidural opioid blockade and chronic pain: preliminary report.
Topics: Adult; Aged; Anesthesia, Epidural; Back Pain; Chronic Disease; Diagnosis, Differential; Female; Fentanyl; Humans; Lidocaine; Male; Middle Aged; Naloxone; Pain; Prognosis; Psychophysiologic Disorders; Sensation; Stress, Psychological | 1985 |
Delayed and prolonged rigidity greater than 24 h following high-dose fentanyl anesthesia.
Topics: Aged; Anesthesia; Fentanyl; Humans; Male; Muscle Rigidity; Naloxone; Time Factors | 1988 |
[Fentanyl reduces the inhibition of dorsal horn lamina V type neuronal activity induced by bradykinin injection into the femoral artery contralateral to the recording site].
Topics: Animals; Bradykinin; Cats; Depression, Chemical; Electric Stimulation; Evoked Potentials; Fentanyl; Injections, Intra-Arterial; Naloxone; Neurons; Spinal Cord | 1988 |
Objective assessment of opioid action by facial muscle surface electromyography (SEMG).
Topics: Adult; Aged; Butorphanol; Electromyography; Evoked Potentials; Facial Muscles; Fentanyl; Humans; Middle Aged; Morphinans; Naloxone; Pain; Pain, Postoperative; Succinylcholine | 1988 |
Delayed respiratory depression following fentanyl anesthesia for cardiac surgery.
Topics: Aged; Anesthesia, Intravenous; Coronary Artery Bypass; Female; Fentanyl; Humans; Male; Middle Aged; Muscle Rigidity; Naloxone; Peak Expiratory Flow Rate; Respiratory Insufficiency; Retrospective Studies; Time Factors | 1988 |
Comparison of the discriminative stimulus properties of U50,488 and morphine in pigeons.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Columbidae; Cyclazocine; Dextroamphetamine; Discrimination Learning; Dose-Response Relationship, Drug; Ethylketocyclazocine; Female; Fentanyl; Methadone; Morphine; Naloxone; Phenazocine; Phencyclidine; Pyrrolidines; Time Factors | 1987 |
Fentanyl suppression of nociceptive neurons in the superficial dorsal horn of the cat.
Topics: Animals; Cats; Depression, Chemical; Dose-Response Relationship, Drug; Evoked Potentials; Female; Fentanyl; Injections, Spinal; Male; Microelectrodes; Naloxone; Neurons; Nociceptors; Spinal Cord; Time Factors | 1988 |
[Rigidity caused by fentanyl during recovery from anesthesia. Description of a clinical case].
Topics: Adult; Anesthesia Recovery Period; Anesthesia, General; Fentanyl; Humans; Intervertebral Disc Displacement; Male; Muscle Rigidity; Naloxone | 1987 |
Improved radioreceptor assay of opiate narcotics in human serum: application to fentanyl and morphine metabolism.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Fentanyl; Humans; Male; Membranes; Morphine; Naloxone; Narcotics; Radioligand Assay; Rats; Rats, Inbred Strains; Reference Values; Software | 1987 |
Effects of fentanyl on peripheral and cerebral hemodynamics in neonatal lambs.
Topics: Animals; Animals, Newborn; Behavior, Animal; Blood Pressure; Cardiac Output; Cerebrovascular Circulation; Fentanyl; Heart Rate; Hemodynamics; Kidney; Naloxone; Oxygen Consumption; Regional Blood Flow; Respiration; Sheep | 1987 |
The inhibitory effect of fentanyl, nicomorphine and 6-nicotinoyl morphine on phrenic nerve activity in relation to their cardiovascular effects in the anaesthetized cat.
Topics: Animals; Cats; Codeine; Fentanyl; Hemodynamics; Injections, Intra-Arterial; Injections, Intravenous; Morphine Derivatives; Naloxone; Nicotinic Acids; Phrenic Nerve; Respiration; Vertebral Artery | 1987 |
Temporal factors influencing the development of acute tolerance to opiates.
Topics: Animals; Cardiovascular System; Dose-Response Relationship, Drug; Drug Tolerance; Female; Fentanyl; Heart Rate; Kinetics; Male; Morphine; Naloxone; Rabbits; Respiration; Respiratory System | 1987 |
Narcotics do not alter the heat response of unmyelinated primary afferents in monkeys.
Topics: Action Potentials; Afferent Pathways; Anesthesia; Animals; Blood Pressure; Electrocardiography; Fentanyl; Halothane; Heart Rate; Hot Temperature; Macaca; Morphine; Naloxone; Narcotics; Nociceptors; Physical Stimulation; Sensation; Skin | 1986 |
Post-operative rigidity after fentanyl administration.
Topics: Aged; Anesthesia; Female; Fentanyl; Humans; Muscle Rigidity; Naloxone; Nitrous Oxide; Postoperative Complications | 1986 |
Activation of cholinergic mechanisms in the medulla oblongata reverse intravenous opioid-induced respiratory depression.
Topics: Analgesia; Animals; Atropine; Blood Pressure; Cholinergic Fibers; Dose-Response Relationship, Drug; Fentanyl; Heart Rate; Isoflurane; Male; Medulla Oblongata; Naloxone; Physostigmine; Prazosin; Rats; Respiration; Scopolamine | 1987 |
The adaptative function of MSH, brain potentials and selective attention in man.
Topics: Attention; Dextroamphetamine; Evoked Potentials, Somatosensory; Fentanyl; Humans; Hypopituitarism; Melanocyte-Stimulating Hormones; Naloxone | 1985 |
Fentanyl and alfentanil suppress brainstem pain transmission.
Topics: Alfentanil; Animals; Brain Stem; Cats; Electric Stimulation; Evoked Potentials; Female; Fentanyl; Injections, Intravenous; Male; Naloxone; Neural Conduction; Pain; Radial Nerve | 1985 |
Morphine enhances gastric mucus synthesis in rats.
Topics: Animals; Atropine; Cimetidine; Fentanyl; Gastric Mucosa; Male; Morphine; Mucus; Naloxone; Rats | 1986 |
Colonic motor responses in the pony: relevance of colonic stimulation by opiate antagonists.
Topics: Animals; Colon; Electromyography; Fentanyl; Horses; Morphine; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Naloxone; Narcotic Antagonists; Oxymorphone | 1985 |
Use of carfentanil and a ketamine-xylazine mixture to immobilise wild grey seals (Halichoerus grypus).
Topics: Animals; Caniformia; Drug Combinations; Female; Fentanyl; Immobilization; Ketamine; Male; Naloxone; Seals, Earless; Thiazines; Xylazine | 1985 |
The effect of fentanyl on the lick/chew response in rabbits.
Topics: Animals; Chlorpromazine; Dental Pulp; Electric Stimulation; Fentanyl; Mastication; Naloxone; Rabbits | 1985 |
Opioid dependence prevents the action of pertussis toxin in the guinea-pig myenteric plexus.
Topics: Animals; Fentanyl; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Naloxone; Neurotoxins; Opioid-Related Disorders; Pertussis Toxin; Virulence Factors, Bordetella | 1985 |
Epidural fentanyl counteracts sympathetic gastric inhibition.
Topics: Animals; Cats; Digestive System Physiological Phenomena; Epidural Space; Fentanyl; Gastrointestinal Motility; Intestinal Obstruction; Kinetics; Naloxone; Neural Inhibition; Reflex; Stomach; Sympathetic Nervous System; Vagus Nerve | 1985 |
Influence of rentanyl, levorphanol and pethidine on the release of noradrenaline from rat brain cortex slices.
Topics: Animals; Cerebral Cortex; Cocaine; Drug Interactions; Electric Stimulation; Fentanyl; In Vitro Techniques; Levorphanol; Meperidine; Naloxone; Neural Inhibition; Norepinephrine; Rats; Stimulation, Chemical; Tritium | 1974 |
[The effects of naloxone (Narcan) on circulation and respiration after neurolept anaesthesia for neurosurgical operations (author's transl)].
Topics: Adolescent; Adult; Aged; Atropine; Blood Circulation; Blood Pressure; Brain Neoplasms; Cardiac Volume; Droperidol; Fentanyl; Heart Rate; Humans; Middle Aged; Naloxone; Neuroleptanalgesia; Preanesthetic Medication; Pulse; Respiration | 1974 |
The use of a narcotic antagonist in the anesthetic management of the ambulatory oral surgery patient.
Topics: Anesthesia, Dental; Atropine; Carbon Dioxide; Catheterization; Diazepam; Female; Fentanyl; Humans; Hydrogen-Ion Concentration; Infusions, Parenteral; Male; Meperidine; Naloxone; Oxygen; Preanesthetic Medication; Respiratory Insufficiency; Scopolamine; Surgery, Oral | 1974 |
Characterization of the acute tolerance and dependence to morphine-induced respiratory depression in decerebrate cats.
Topics: Animals; Cats; Cerebral Decortication; Drug Tolerance; Female; Fentanyl; Heart Rate; Injections, Intravenous; Male; Morphine; Naloxone; Pentobarbital; Respiration; Respiratory Function Tests | 1972 |
An evaluation of naloxone as a narcotic antagonist in the dog.
Topics: Anesthesia, Inhalation; Animals; Blood Pressure; Carbon Dioxide; Dog Diseases; Dogs; Droperidol; Female; Fentanyl; Heart Rate; Hydrogen-Ion Concentration; Injections, Intramuscular; Injections, Intravenous; Male; Morphine; Naloxone; Neuroleptanalgesia; Nitrous Oxide; Oxygen | 1973 |
Effects of narcotic analgesics and their antagonists on the rabbit isolated heart and its adrenergic nerves.
Topics: Animals; Autonomic Nervous System; Drug Interactions; Electric Stimulation; Female; Fentanyl; Heart; Heart Rate; In Vitro Techniques; Levallorphan; Male; Meperidine; Methadone; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Norepinephrine; Perfusion; Rabbits; Secretory Rate; Sympathetic Nervous System | 1973 |
The effect of morphine, meperidine, fentanyl and naloxone on the oxyhemoglobin dissociation curve.
Topics: Adult; Carbon Dioxide; Diphosphoglyceric Acids; Electrophoresis; Female; Fentanyl; Hematocrit; Hemoglobins; Humans; Hydrogen-Ion Concentration; Male; Meperidine; Morphine; Naloxone; Oxygen; Oxygen Consumption; Oxyhemoglobins; Sex Factors | 1974 |
Naloxone-induced facilitation of contractions, spontaneous activity and tolerance to morphine in ileum of morphine-dependent guinea-pigs.
Topics: Animals; Dose-Response Relationship, Drug; Drug Tolerance; Electric Stimulation; Fentanyl; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Morphine; Morphine Dependence; Muscle Contraction; Muscle, Smooth; Naloxone | 1974 |
Morphiceptin: biphasic inhibition of mu-opiate receptor ligands.
Topics: Analgesics; Animals; Binding, Competitive; Brain; Endorphins; Fentanyl; In Vitro Techniques; Kinetics; Membranes; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu | 1984 |
Estimation of high pressure liquid chromatographic retention indices of narcotic analgetics and related drugs.
Topics: Analgesics, Opioid; Butanones; Chromatography, High Pressure Liquid; Fentanyl; Ketones; Naloxone; Octanols; Oxycodone; Oxymorphone; Water | 1980 |
Comparative cardiac contractile actions of six narcotic analgesics: morphine, meperidine, pentazocine, fentanyl, methadone and l-alpha-acetylmethadol (LAAM).
Topics: Analgesics, Opioid; Animals; Cats; Depression, Chemical; Drug Interactions; Fentanyl; Meperidine; Methadone; Methadyl Acetate; Morphine; Myocardial Contraction; Naloxone; Pentazocine; Stimulation, Chemical | 1980 |
[Competitive study of the effects of naloxone and of almitrine on fentanyl analgesia in the anesthetized dog: effects on the muzzle opening reflex and blood gases].
Topics: Almitrine; Analgesia; Anesthesia; Animals; Blood Gas Analysis; Dogs; Fentanyl; Mouth; Naloxone; Piperazines; Reflex; Respiration; Triazines | 1980 |
Pharmacology of narcotic analgesics in the horse: selective blockade of narcotic-induced locomotor activity.
Topics: Acepromazine; Analgesics, Opioid; Animals; Fentanyl; Furosemide; Horses; Morphine; Motor Activity; Naloxone; Phenylbutazone | 1981 |
Antagonism of the respiratory effects of alfentanil and fentanyl by naloxone in the conscious rabbit.
Topics: Alfentanil; Analgesics, Opioid; Animals; Carbon Dioxide; Dose-Response Relationship, Drug; Female; Fentanyl; Hydrogen-Ion Concentration; Male; Naloxone; Rabbits; Respiratory Function Tests; Tidal Volume | 1981 |
Inhibition of ganglionic transmission by narcotic analgesics; an effect antagonized by naloxone, nalorphine and calcium.
Topics: Analgesics, Opioid; Animals; Calcium; Fentanyl; Ganglia, Sympathetic; Methadone; Morphine Derivatives; Nalorphine; Naloxone; Neural Inhibition; Oxycodone; Rana esculenta; Rats; Rats, Inbred Strains; Receptors, Opioid; Time Factors | 1981 |
Double-blind comparison of the postoperative respiratory depressant effects of alfentanil and fentanyl.
Topics: Adult; Alfentanil; Analgesics, Opioid; Anesthesia; Double-Blind Method; Female; Fentanyl; Hemodynamics; Humans; Naloxone; Postoperative Complications; Respiration Disorders | 1982 |
Reversal of the neuroleptanalgesic effect of droperidolfentanyl in the dog by 4-aminopyridine and naloxone.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Blood Pressure; Cardiovascular Agents; Central Nervous System Stimulants; Dogs; Droperidol; Drug Combinations; Drug Therapy, Combination; Female; Fentanyl; Heart Rate; Male; Naloxone; Respiration; Yohimbine | 1982 |
Reduction of diazepam dose and complications by hypnosis and an opioid analgesic (a study of 409 consecutive dental patients).
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Anesthesia, Dental; Anesthesia, General; Child; Child, Preschool; Diazepam; Female; Fentanyl; Humans; Hypnosis, Dental; Infant; Male; Meperidine; Middle Aged; Naloxone; Pentazocine | 1982 |
Prevention of late fentanyl-induced respiratory depression after the injection of opiate antagonists naltrexone and S-20682: comparison with naloxone.
Topics: Animals; Carbon Dioxide; Depression, Chemical; Dogs; Electroencephalography; Fentanyl; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Oxygen; Partial Pressure; Respiration; Time Factors | 1983 |
In vitro binding properties of 3H-sufentanil, a superior ligand for the mu-opiate receptor.
Topics: Analgesics, Opioid; Animals; Brain; Dihydromorphine; Fentanyl; In Vitro Techniques; Kinetics; Membranes; Naloxone; Rats; Receptors, Opioid; Receptors, Opioid, mu; Spinal Cord; Stereoisomerism; Sufentanil | 1982 |
Interaction of peptides and morphine-like narcotic analgesics with specifically labelled mu- and delta-opiate receptor binding sites.
Topics: Analgesics, Opioid; Animals; Brain; Endorphins; Fentanyl; In Vitro Techniques; Membranes; Morphine; Naloxone; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sufentanil | 1983 |
In vivo characterization of four types of opioid binding sites in rat brain.
Topics: Analgesics, Opioid; Animals; Brain; Buprenorphine; Diprenorphine; Etorphine; Fentanyl; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Sufentanil; Tritium | 1983 |
New narcotic agonists and antagonists in anaesthesia.
Topics: Adjuvants, Anesthesia; Alfentanil; Analgesics, Opioid; Anesthesia, General; Fentanyl; Humans; Naloxone; Narcotic Antagonists; Pain, Postoperative; Preanesthetic Medication; Sufentanil | 1984 |
Receptor preference of dynorphin A fragments in the mouse vas deferens determined by different techniques.
Topics: Animals; Drug Tolerance; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Fentanyl; Male; Mice; Naloxone; Naltrexone; Peptide Fragments; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Vas Deferens | 1984 |
Opioid receptor agonists in the rabbit colon: comparison of in vivo and in vitro studies.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Colon; Cyclazocine; Dynorphins; Electric Conductivity; Enkephalins; Ethylketocyclazocine; Fentanyl; Male; Morphine; Naloxone; Narcotics; Pyrrolidines; Rabbits; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1984 |
Kinetics of brain receptor binding inhibition by endogenous macromolecular substances [proceedings].
Topics: Animals; Apomorphine; Brain; Fentanyl; Haloperidol; Kinetics; Naloxone; Rats; Receptors, Drug; Receptors, Opioid; Receptors, Serotonin | 1980 |
[Effect of fentanyl on midbrain units and its antagonism by naloxone in rabbits].
Topics: Animals; Fentanyl; Mesencephalon; Naloxone; Rabbits | 1982 |
Excitatory action of opioid peptides and opiates on cultured hippocampal pyramidal cells.
Topics: Animals; Culture Techniques; Dose-Response Relationship, Drug; Endorphins; Enkephalins; Evoked Potentials; Fentanyl; Hippocampus; Morphine; Naloxone; Neurons; Rats; Synaptic Transmission | 1980 |
Control of guinea pig intestinal electrolyte secretion by a delta-opiate receptor.
Topics: Animals; Chlorides; Electric Conductivity; Endorphins; Etorphine; Female; Fentanyl; Guinea Pigs; Intestinal Mucosa; Membrane Potentials; Morphine; Muscle, Smooth; Naloxone; Receptors, Opioid | 1980 |
Opiate system influences central respiratory chemosensors.
Topics: Animals; Brain; Cats; Chemoreceptor Cells; Fentanyl; Medulla Oblongata; Naloxone; Phrenic Nerve; Receptors, Opioid; Respiration | 1981 |
Opiate action on adenohypophyseal hormone secretion during anesthesia and gynecologic surgery in different phases of the menstrual cycle.
Topics: Adult; Anesthesia; Anesthesia, General; Anesthesia, Inhalation; Endorphins; Female; Fentanyl; Genital Diseases, Female; Hemorrhage; Humans; Menstruation; Naloxone; Narcotics; Nociceptors; Pain, Postoperative; Pituitary Hormones, Anterior; Prospective Studies; Receptors, Opioid | 1981 |
D-Ala2,D-Leu5-enkephalin generalizes to a discriminative stimulus produced by fentanyl but not ethylketocyclazocine.
Topics: Animals; Cyclazocine; Discrimination, Psychological; Endorphins; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Fentanyl; Generalization, Stimulus; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid | 1982 |
[Interaction of seven 3-methyl fentanyl compounds with cerebroside sulfate (author's transl)].
Topics: Analgesics; Animals; Cattle; Cerebrosides; Drug Interactions; Fentanyl; Naloxone; Receptors, Opioid; Swine | 1981 |
Naloxone does not antagonize the anesthetic-induced depression of nociceptor-driven spinal cord response in spinal cats.
Topics: Anesthetics; Animals; Cats; Enflurane; Ether; Female; Fentanyl; Halothane; Male; Naloxone; Nitrous Oxide; Nociceptors; Receptors, Opioid; Spinal Cord; Thiamylal | 1981 |
Potential affinity labels for the opiate receptor based on fentanyl and related compounds.
Topics: Affinity Labels; Animals; Chemical Phenomena; Chemistry; Fentanyl; In Vitro Techniques; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Opioid | 1982 |
Intraseptally injected opiate agents: effects on morphine-induced behaviour of cats.
Topics: Animals; Behavior, Animal; beta-Endorphin; Cats; Endorphins; Enkephalin, Methionine; Fentanyl; Morphine; Naloxone; Naltrexone; Narcotics; Receptors, Opioid; Septal Nuclei; Septum Pellucidum | 1982 |
An analysis of nicotinic and opioid processes in the medulla oblongata and nucleus ambiguus of the dog.
Topics: Animals; Blood Pressure; Cyclazocine; Decerebrate State; Dogs; Electric Stimulation; Endorphins; Ethylketocyclazocine; Female; Fentanyl; Heart Rate; Male; Mecamylamine; Medulla Oblongata; Naloxone; Nicotine; Phenazocine; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Receptors, sigma | 1983 |
Opioid antinociception and positive reinforcement are mediated by different types of opioid receptors.
Topics: Analgesics; Animals; Diprenorphine; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Fentanyl; Hypothalamic Area, Lateral; Male; Morphinans; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Tegmentum Mesencephali | 1983 |
Effects of mu- and kappa-opioid receptor agonists on urinary output in mice.
Topics: Animals; Benzomorphans; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Fentanyl; Male; Mice; Morphine; Naloxone; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Species Specificity; Stimulation, Chemical; Urination | 1983 |
Central cardiovascular effects of kappa agonists dynorphin-(1-13) and ethylketocyclazocine in the anaesthetized rat.
Topics: Animals; beta-Endorphin; Blood Pressure; Cyclazocine; Dynorphins; Endorphins; Enkephalin, Methionine; Ethylketocyclazocine; Fentanyl; Heart Rate; Male; Naloxone; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Vagus Nerve | 1983 |
Opiate receptor binding-effect relationship: sufentanil and etorphine produce analgesia at the mu-site with low fractional receptor occupancy.
Topics: Animals; Brain; Diprenorphine; Drug Interactions; Etorphine; Fentanyl; Morphinans; Naloxone; Pain; Rats; Receptors, Opioid; Sufentanil | 1984 |
Discrimination of three types of opioid binding sites in rat brain in vivo.
Topics: Animals; Binding, Competitive; Brain; Diprenorphine; Etorphine; Fentanyl; Male; Naloxone; Rats; Receptors, Opioid; Sufentanil | 1984 |
[Continuous alfentanil infusion in surgical interventions of intermediate and long duration].
Topics: Adolescent; Adult; Aged; Alfentanil; Anesthesia, Intravenous; Female; Fentanyl; Heart Rate; Humans; Male; Middle Aged; Muscles; Naloxone; Preanesthetic Medication; Resuscitation; Surgical Procedures, Operative; Time Factors | 1984 |
Pharmacodynamics of opiates.
Topics: Analgesia; Anesthesia; Anesthetics; Animals; Carbon Dioxide; Depression, Chemical; Dogs; Drug Synergism; Fentanyl; Humans; Meperidine; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Oxygen; Oxygen Consumption; Respiration; Respiratory Function Tests | 1984 |
Factors regulating drug cue sensitivity: the effect of frustrative non-reward in fentanyl-saline discrimination.
Topics: Animals; Cues; Discrimination Learning; Dose-Response Relationship, Drug; Fentanyl; Frustration; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Sodium Chloride; Sufentanil | 1981 |
Origin of the hypotensive and sympathoinhibitory effect of morphinomimetic agents.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Carotid Sinus; Dogs; Female; Fentanyl; Male; Medulla Oblongata; Naloxone; Narcotics; Splanchnic Nerves; Sympatholytics; Vagotomy | 1983 |
[Important side-effects of naloxone as an antagonist of neuroleptoanalgesia].
Topics: Aged; Anesthetics; Atropine; Cardiovascular System; Colectomy; Droperidol; Drug Combinations; Female; Fentanyl; Gastrectomy; Humans; Hypertension; Male; Middle Aged; Naloxone; Neuroleptanalgesia; Preanesthetic Medication; Pulmonary Edema; Respiratory Insufficiency; Thyroidectomy | 1983 |
Naloxone and alcohol intoxication in the dog.
Topics: Alcoholic Intoxication; Animals; Blood Glucose; Dogs; Ethanol; Fentanyl; Humans; Naloxone; Postural Balance; Respiration | 1983 |
Catatonic or hypotonic immobility induced in mice by intracerebroventricular injection of mu or kappa opioid receptor agonists as well as enkephalins or inhibitors of their degradation.
Topics: Animals; Benzomorphans; Catatonia; Cyclazocine; Enkephalins; Ethylketocyclazocine; Fentanyl; Humans; Immobilization; Injections, Intraventricular; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; Narcotics | 1983 |
High dose fentanyl-oxygen anesthesia for intracranial mycotic aneurysm surgery: a clinical report.
Topics: Adult; Anesthesia; Aneurysm, Infected; Female; Fentanyl; Heart Valve Diseases; Humans; Intracranial Aneurysm; Naloxone; Oxygen; Postoperative Care | 1983 |
The effect of fentanyl on arginine vasopressin and cortisol secretion during anesthesia.
Topics: Adult; Anesthesia; Arginine Vasopressin; Female; Fentanyl; Halothane; Humans; Hydrocortisone; Naloxone | 1984 |
Agonist and antagonist effects of prototype opiate drugs in rats discriminating fentanyl from saline: characteristics of partial generalization.
Topics: Animals; Conditioning, Operant; Cyclazocine; Discrimination Learning; Ethylketocyclazocine; Fentanyl; Male; Morphine; Nalorphine; Naloxone; Narcotics; Phenazocine; Rats; Rats, Inbred Strains; Sodium Chloride | 1984 |
Fentanyl in the fourth cerebral ventricle causes respiratory depression in the anesthetized but not in the awake dog.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Animals; Carbon Dioxide; Cerebral Ventricles; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Electroencephalography; Fentanyl; Halothane; Naloxone; Perfusion; Respiration; Wakefulness | 1981 |
Local and distal effects induced by unilateral striatal application of opiates in the absence or in the presence of naloxone on the release of dopamine in both caudate nuclei and substantiae nigrae of the cat.
Topics: Animals; Cats; Caudate Nucleus; Corpus Striatum; Dopamine; Enkephalin, Methionine; Female; Fentanyl; Functional Laterality; Male; Morphine; Naloxone; Narcotics; Structure-Activity Relationship; Substantia Nigra | 1983 |
Synthesis and evaluation of 1- and 2-substituted fentanyl analogues for opioid activity.
Topics: Animals; Enkephalin, Methionine; Enkephalins; Fentanyl; Guinea Pigs; Ileum; Male; Mice; Morphine; Naloxone; Vas Deferens | 1983 |
Reversal of fentanyl induced spasm of the sphincter of Oddi.
Topics: Ampulla of Vater; Atropine; Fentanyl; Glucagon; Humans; Manometry; Naloxone; Parasympatholytics; Sodium Chloride; Spasm; Sphincter of Oddi | 1983 |
Narcotic antagonism by naloxone. Few side-effects after a short procedure?
Topics: Aged; Anesthesia, General; Arrhythmias, Cardiac; Blood Pressure; Female; Fentanyl; Heart Rate; Humans; Laryngoscopy; Male; Middle Aged; Naloxone; Time Factors | 1983 |
Effects of fentanyl, naloxone, and clonidine on hemodynamics and plasma catecholamine levels in dogs.
Topics: Anesthesia, General; Animals; Atropine; Catecholamines; Clonidine; Dogs; Drug Interactions; Fentanyl; Hemodynamics; Naloxone; Tolazoline | 1983 |
Biphasic respiratory depression from neurolept anesthesia.
Topics: Adipose Tissue; Fentanyl; Humans; Naloxone; Neuroleptanalgesia | 1983 |
Dose-response suppression of noxiously evoked activity of WDR neurons by spinally administered fentanyl.
Topics: Action Potentials; Animals; Cats; Dose-Response Relationship, Drug; Evoked Potentials; Female; Fentanyl; Male; Naloxone; Neurons; Pain; Spinal Cord | 1983 |
High-dose fentanyl for neuroanesthesia.
Topics: Adult; Aged; Anesthesia, Intravenous; Brain Neoplasms; Cranial Nerves; Fentanyl; Hemodynamics; Humans; Middle Aged; Naloxone; Neurosurgery; Oxygen; Posture | 1983 |
Selective effect of fentanyl on group III and IV somatosympathetic reflexes.
Topics: Animals; Dogs; Drug Antagonism; Drug Tolerance; Electric Stimulation; Evoked Potentials; Fentanyl; Naloxone; Radial Nerve; Reflex; Sympathetic Nervous System | 1983 |
Effect of fentanyl and naloxone on somatic and auditory evoked potentials in man.
Topics: Evoked Potentials, Auditory; Evoked Potentials, Somatosensory; Fentanyl; Humans; Muscles; Naloxone | 1983 |
Opioid and nonopioid behavioral effects of methadone isomers.
Topics: Animals; Behavior, Animal; Columbidae; Conditioning, Operant; Drug Tolerance; Fentanyl; Kinetics; Male; Methadone; Naloxone; Pentobarbital; Stereoisomerism | 1982 |
The antinociceptive effects of epidural opiates in the cat: studies of the pharmacology and the effects of lipophilicity in spinal analgesia.
Topics: Animals; Cats; Dose-Response Relationship, Drug; Epidural Space; Female; Fentanyl; Lipids; Male; Meperidine; Methadone; Morphine; Naloxone; Narcotics; Nociceptors; Pain; Reflex; Skin; Time Factors | 1982 |
Effects of naloxone and fentanyl in acutely decerebrated dogs.
Topics: Animals; Blood Pressure; Brain; Brain Stem; Cardiovascular System; Dogs; Female; Fentanyl; Heart Rate; Male; Naloxone; Reflex; Respiration; Skin Physiological Phenomena | 1982 |
Naloxone induces excitation of the cardiovascular system and a rise in myocardial oxygen consumption in fentanyl and meperidine-anesthetized dogs.
Topics: Anesthesia, General; Animals; Cardiac Catheterization; Dogs; Fentanyl; Hemodynamics; Meperidine; Myocardium; Naloxone; Oxygen Consumption | 1982 |
[Analgesia in cesarean sections: its impact on the newborn infant in the presence or absence of naloxone].
Topics: Adult; Analgesics; Anesthesia, Obstetrical; Apgar Score; Cesarean Section; Female; Fentanyl; Humans; Infant, Newborn; Naloxone; Pentazocine; Pregnancy | 1982 |
[Effects of analgesics on coronary hemodynamics and myocardial contraction--(1) Thalamonal, fentanyl, pethidine, and naloxone].
Topics: Analgesics; Animals; Coronary Circulation; Dogs; Droperidol; Drug Combinations; Fentanyl; Meperidine; Myocardial Contraction; Naloxone | 1982 |
Effects of fentanyl, and the antagonism by naloxone, on regional blood flow and biochemical variables in conscious rabbits.
Topics: Animals; Blood Gas Analysis; Blood Glucose; Blood Pressure; Cardiac Output; Fatty Acids, Nonesterified; Female; Fentanyl; Heart Rate; Male; Naloxone; Rabbits; Regional Blood Flow; Respiration | 1982 |
Increased naloxone reversibility in fentanyl dose-dose discrimination.
Topics: Animals; Discrimination, Psychological; Dose-Response Relationship, Drug; Fentanyl; Generalization, Stimulus; Naloxone; Rats; Rats, Inbred Strains | 1982 |
Biphasic respiratory depression from neurolept anesthesia.
Topics: Adult; Droperidol; Fentanyl; Humans; Male; Naloxone; Neuroleptanalgesia; Nitrous Oxide; Respiratory Insufficiency | 1982 |
Gastric relaxation and vomiting by apomorphine, morphine and fentanyl in the conscious dog.
Topics: Animals; Apomorphine; Dogs; Dopamine Antagonists; Drug Interactions; Female; Fentanyl; Morphine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naloxone; Pressure; Stomach; Vomiting | 1981 |
Modulation of the jaw-opening reflex by peripheral electrical stimulation.
Topics: Action Potentials; Afferent Pathways; Animals; Electric Stimulation; Facial Muscles; Fentanyl; Jaw; Male; Naloxone; Picrotoxin; Rats; Rats, Inbred Strains; Reflex; Tooth | 1981 |
Self-administration of clonidine by the rat.
Topics: Animals; Azaperone; Clonidine; Fentanyl; Haloperidol; Infusions, Parenteral; Male; Muridae; Naloxone; Reinforcement Schedule; Self Administration | 1981 |
Failure of naloxone to prevent the emetic activity of apomorphine in dogs.
Topics: Animals; Apomorphine; Dogs; Droperidol; Female; Fentanyl; Haloperidol; Injections, Intravenous; Male; Naloxone; Time Factors; Vomiting | 1981 |
Cardiovascular effects on selective perfusion of the fourth cerebral ventricle in cats with fentanyl, naloxone & methohexital.
Topics: Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Cats; Cerebral Ventricles; Female; Fentanyl; Heart Rate; Male; Methohexital; Naloxone | 1980 |
Factors regulating drug cue sensitivity: the effect of training dose in fentanyl-saline discrimination.
Topics: Animals; Apomorphine; Cues; Cyclazocine; Dextroamphetamine; Discrimination Learning; Dose-Response Relationship, Drug; Drug Administration Schedule; Fentanyl; Generalization, Stimulus; Male; Morphine; Naloxone; Rats; Research Design; Sodium Chloride | 1980 |
Perfusion of fentanyl through the fourth cerebral ventricle and its cardiovascular effects in awake and halothane anesthetised dogs.
Topics: Animals; Blood Pressure; Cerebral Ventricles; Dogs; Drug Interactions; Fentanyl; Halothane; Heart Rate; Hemodynamics; Naloxone; Perfusion; Reflex | 1980 |
Action of the morphinometic agent, fentanyl, on the nucleas tractus solitarii and the nucleus ambiguus cardiovascular neurons.
Topics: Animals; Blood Pressure; Cardiovascular System; Dogs; Electrophysiology; Female; Fentanyl; Male; Naloxone; Neurons; Pressoreceptors | 1980 |
Capture of wood bison (Bison bison athabascae) using carfentanil-based mixtures.
Topics: Analgesics, Opioid; Animals; Bison; Diprenorphine; Drug Combinations; Female; Fentanyl; Hypnotics and Sedatives; Immobilization; Injections, Intramuscular; Injections, Intravenous; Injections, Subcutaneous; Male; Naloxone; Naltrexone; Narcotic Antagonists; Northwest Territories; Piperidines; Tranquilizing Agents; Xylazine | 1995 |
Effects of intravenous anesthetics on phosphatidylinositol turnover in rat cerebral cortical prisms.
Topics: Anesthetics, Intravenous; Animals; Cerebral Cortex; Diazepam; Dose-Response Relationship, Drug; Droperidol; Fentanyl; Flumazenil; Inositol Phosphates; Ketamine; Male; Naloxone; Norepinephrine; Phosphatidylinositols; Prazosin; Rats; Rats, Wistar; Thiamylal | 1994 |
Activity changes in rat raphe magnus neurons at different concentrations of fentanyl in vitro.
Topics: Action Potentials; Animals; Fentanyl; In Vitro Techniques; Naloxone; Neurons; Raphe Nuclei; Rats; Rats, Wistar | 1995 |
Complications with the use of carfentanil citrate and xylazine hydrochloride to immobilize domestic horses.
Topics: Analgesics, Opioid; Animals; Animals, Domestic; Fentanyl; Horse Diseases; Horses; Hypertension; Immobilization; Naloxone; Naltrexone; Pulmonary Edema; Tachycardia; Xylazine | 1995 |
Immobilization stress-induced oral opioid self-administration and withdrawal in rats: role of conditioning factors and the effect of stress on "relapse" to opioid drugs.
Topics: Animals; Conditioning, Psychological; Corticosterone; Fentanyl; Immobilization; Male; Morphine; Morphine Dependence; Naloxone; Narcotics; Rats; Rats, Wistar; Recurrence; Self Administration; Stress, Psychological; Substance Withdrawal Syndrome | 1993 |
Anesthetic and hemodynamic interactions of dexmedetomidine and fentanyl in dogs.
Topics: Adrenergic alpha-Antagonists; Anesthetics; Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Enflurane; Fentanyl; Heart Rate; Hemodynamics; Imidazoles; Medetomidine; Models, Biological; Naloxone; Pulmonary Alveoli | 1994 |
Comparison of [11C]diprenorphine and [11C]carfentanil in vivo binding to opiate receptors in man using a dual detector system.
Topics: Analgesics, Opioid; Binding Sites; Diprenorphine; Dose-Response Relationship, Drug; Fentanyl; Gamma Rays; Humans; Naloxone; Receptors, Opioid; Receptors, Opioid, mu | 1994 |
[Effect of agonists of opioid receptor on coronary arterial strips in porcine].
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Coronary Vessels; Fentanyl; Haloperidol; In Vitro Techniques; Morphine; Muscle Contraction; Muscle, Smooth, Vascular; Naloxone; Pyrrolidines; Receptors, Opioid; Swine | 1994 |
One year's experience with an acute pain service in a Spanish University Clinic hospital.
Topics: Academic Medical Centers; Analgesia, Epidural; Analgesia, Patient-Controlled; Bupivacaine; Fentanyl; Hospitals, University; Humans; Infusion Pumps; Monitoring, Physiologic; Morphine; Naloxone; Pain Clinics; Pain Measurement; Pain, Postoperative; Pruritus; Respiration; Respiration Disorders; Spain | 1994 |
Delayed awakening from general anaesthesia in a patient with Hunter syndrome.
Topics: Anesthesia Recovery Period; Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Intravenous; Child; Consciousness; Enflurane; Fentanyl; Humans; Male; Mucopolysaccharidosis II; Naloxone; Nitrous Oxide; Respiratory Insufficiency | 1994 |
Fentanyl stimulates atrial natriuretic peptide secretion.
Topics: Animals; Atrial Natriuretic Factor; Cells, Cultured; Female; Fentanyl; Microscopy, Electron; Mitochondria; Myocardial Contraction; Myocardium; Myofibrils; Naloxone; Pregnancy; Radioimmunoassay; Rats; Rats, Wistar; Sarcomeres; Sarcoplasmic Reticulum; Time Factors | 1994 |
Binding of fentanyl and pethidine to muscarinic receptors in rat brain.
Topics: Animals; Brain; Fentanyl; In Vitro Techniques; Male; Meperidine; Naloxone; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Receptors, Muscarinic | 1994 |
Epidural narcotic analgesia after thoracotomy.
Topics: Adult; Aged; Aged, 80 and over; Analgesia, Epidural; Blood Gas Analysis; Carbon Dioxide; Drug Costs; Drug Interactions; Female; Fentanyl; Humans; Intraoperative Care; Intubation, Intratracheal; Lung Volume Measurements; Male; Middle Aged; Morphine; Naloxone; Pain, Postoperative; Pruritus; Respiratory Insufficiency; Retrospective Studies; Thoracotomy; Time Factors | 1993 |
Mu- and delta-opioid receptors inhibitorily linked to dopamine-sensitive adenylate cyclase in rat striatum display a selectivity profile toward endogenous opioid peptides different from that of presynaptic mu, delta and kappa receptors.
Topics: Acetylcholine; Adenylyl Cyclases; Animals; Corpus Striatum; Dopamine; Endorphins; Enkephalins; Fentanyl; In Vitro Techniques; Isothiocyanates; Male; Naloxone; Norepinephrine; Protease Inhibitors; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Opioid, delta; Receptors, Opioid, mu; Receptors, Presynaptic; Sulpiride | 1993 |
Lack of a ceiling effect for intrathecal buprenorphine on C fibre mediated somatosympathetic reflexes.
Topics: Animals; Blood Pressure; Buprenorphine; Dogs; Dose-Response Relationship, Drug; Fentanyl; Naloxone; Nerve Fibers; Nerve Fibers, Myelinated; Radial Nerve; Reflex; Tibial Nerve | 1993 |
Fentanyl inhibits the uptake of [3H]noradrenaline in cultured neuronal cells.
Topics: Adrenal Gland Neoplasms; Animals; Dose-Response Relationship, Drug; Fentanyl; Humans; Imipramine; Morphine; Naloxone; Neuroblastoma; Neurons; Norepinephrine; Pheochromocytoma; Rats; Time Factors; Tumor Cells, Cultured | 1993 |
Effect of stress on oral fentanyl consumption in rats in an operant self-administration paradigm.
Topics: Animals; Body Weight; Conditioning, Operant; Drinking; Electroshock; Fentanyl; Male; Naloxone; Rats; Rats, Wistar; Reinforcement Schedule; Self Administration; Stress, Psychological; Taste | 1993 |
Opioid antagonist-induced receptor upregulation: effects of concurrent agonist administration.
Topics: Animals; Brain; Drug Combinations; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Etorphine; Fentanyl; Male; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid, mu; Up-Regulation | 1994 |
Effects of fentanyl on the rat aorta are mediated by alpha-adrenoceptors rather than by the endothelium.
Topics: Animals; Aorta, Thoracic; Culture Techniques; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Fentanyl; Male; Naloxone; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Vasodilation | 1993 |
Spinal and cortical evoked potential studies in the ketamine-anesthetized rabbit: fentanyl exerts component-specific, naloxone-reversible changes dependent on stimulus intensity.
Topics: Anesthesia; Animals; Blood Pressure; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Evoked Potentials, Somatosensory; Female; Fentanyl; Ketamine; Male; Naloxone; Rabbits; Sensitivity and Specificity; Spinal Cord | 1994 |
Opioid receptor regulation in mice.
Topics: Analgesics; Animals; Brain; Etorphine; Fentanyl; Male; Mice; Morphine; Naloxone; Narcotics; Receptors, Opioid, mu | 1993 |
Increased release of immunoreactive cholecystokinin octapeptide by morphine and potentiation of mu-opioid analgesia by CCKB receptor antagonist L-365,260 in rat spinal cord.
Topics: Analgesia; Analgesics; Animals; Benzodiazepinones; Devazepide; Dose-Response Relationship, Drug; Fentanyl; Injections, Spinal; Male; Morphine; Naloxone; Nociceptors; Pain Threshold; Phenylurea Compounds; Radioimmunoassay; Rats; Rats, Wistar; Receptors, Cholecystokinin; Receptors, Opioid, mu; Sincalide; Spinal Cord; Subarachnoid Space | 1993 |
Duration of opioid antagonism by nalmefene and naloxone in the dog: an integrated pharmacokinetic/pharmacodynamic comparison.
Topics: Animals; Blood Gas Monitoring, Transcutaneous; Dogs; Female; Fentanyl; Infusions, Intravenous; Models, Biological; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Respiration | 1995 |
Intravenous opioids stimulate norepinephrine and acetylcholine release in spinal cord dorsal horn. Systematic studies in sheep and an observation in a human.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Dialysis; Dioxanes; Dopamine; Female; Fentanyl; Humans; Idazoxan; Imidazoles; Injections, Intravenous; Male; Microchemistry; Morphine; Naloxone; Narcotic Antagonists; Norepinephrine; Receptors, Adrenergic, alpha-2; Sheep; Spinal Cord; Stimulation, Chemical | 1996 |
Duration of opioid antagonism by nalmefene and naloxone in the dog. A nonparametric pharmacodynamic comparison based on generalized cross-validated spline estimation.
Topics: Analysis of Variance; Animals; Carbon Dioxide; Computer Simulation; Cross-Over Studies; Dogs; Drug Tolerance; Fentanyl; Injections, Intravenous; Male; Models, Statistical; Naloxone; Naltrexone; Narcotic Antagonists; Respiratory Insufficiency; Time Factors | 1995 |
Direct effects of fentanyl on canine coronary artery rings.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Intravenous; Animals; Arteries; Calcium Channel Blockers; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Female; Fentanyl; In Vitro Techniques; Indomethacin; Male; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Nifedipine; Prazosin; Propranolol; Vasoconstriction | 1995 |
Antinociceptive actions of intrathecal xylazine: interactions with spinal cord opioid pathways.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Bicuculline; Dioxanes; Dose-Response Relationship, Drug; Electric Stimulation; Fentanyl; Idazoxan; Imidazoles; Male; Naloxone; Nociceptors; Rats; Rats, Wistar; Reaction Time; Receptors, Opioid; Spinal Cord; Xylazine | 1996 |
[Clinical investigations of an i.m. combination anesthesia with fentanylclimazolam/xylazine and postoperative i.v. antagonism with naloxone/sarmazenil/yohimbine in guinea pigs].
Topics: Anesthesia, General; Anesthetics, Intravenous; Animals; Anti-Anxiety Agents; Benzodiazepines; Drug Combinations; Female; Fentanyl; Guinea Pigs; Imidazoles; Injections, Intramuscular; Injections, Intravenous; Male; Midazolam; Naloxone; Narcotic Antagonists; Xylazine; Yohimbine | 1996 |
Reversal by naloxone of the spinal antinociceptive actions of a systemically-administered NSAID.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Clonixin; Dose-Response Relationship, Drug; Electrophysiology; Excipients; Fentanyl; Inflammation; Male; Naloxone; Narcotic Antagonists; Rats; Rats, Wistar | 1996 |
A comparison of the local anesthetic effects of meperidine, fentanyl, and sufentanil on dorsal root axons.
Topics: Action Potentials; Analgesics, Opioid; Anesthetics, Local; Animals; Axons; Fentanyl; Male; Meperidine; Naloxone; Narcotic Antagonists; Nerve Fibers; Nerve Fibers, Myelinated; Neural Conduction; Neural Pathways; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Sensation; Spinal Nerve Roots; Sufentanil | 1996 |
Effects of the delta opioid against BW373U86 in pigeons trained to discriminate fentanyl, bremazocine and water in a three-choice drug discrimination procedure.
Topics: Analgesics; Animals; Benzamides; Benzomorphans; Columbidae; Discrimination, Psychological; Female; Fentanyl; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Piperazines; Receptors, Opioid, delta | 1996 |
Interaction between opioid and muscarinic receptors in the guinea-pig ileum preparation: a mathematical model.
Topics: Animals; Fentanyl; Guinea Pigs; Ileum; In Vitro Techniques; Male; Meperidine; Models, Biological; Morphine; Naloxone; Receptors, Muscarinic; Receptors, Opioid | 1996 |
Evidence for mu1-opioid receptor involvement in fentanyl-mediated respiratory depression.
Topics: Animals; Carbon Dioxide; Fentanyl; Naloxone; Oxygen; Rats; Receptors, Opioid, mu; Respiration; Respiratory Insufficiency | 1996 |
Sensitization to the conditioned rewarding effects of morphine: pharmacology and temporal characteristics.
Topics: Animals; Conditioning, Psychological; Dose-Response Relationship, Drug; Fentanyl; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Time Factors | 1996 |
Studies on the abstinence-like overshoot following reversal of the potent 19-isoamyl derivative of etorphine with naloxone. A comparison with the opioids fentanyl and alfentanil.
Topics: Alfentanil; Analgesics, Opioid; Animals; Blood Gas Analysis; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Etorphine; Fentanyl; Heart Rate; Naloxone; Narcotic Antagonists; Receptors, Opioid, mu; Substance Withdrawal Syndrome | 1997 |
Reversal by kappa-agonists of peritoneal irritation-induced ileus and visceral pain in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetic Acid; Analgesics; Animals; Benzofurans; Benzomorphans; Cyclazocine; Fentanyl; Gastric Emptying; Intestinal Pseudo-Obstruction; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Peritoneum; Pyrroles; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Thiophenes | 1997 |
Preferences for tastes paired with a nicotine antagonist in rats chronically treated with nicotine.
Topics: Animals; Conditioning, Psychological; Fentanyl; Food Preferences; Male; Mecamylamine; Naloxone; Narcotic Antagonists; Narcotics; Nicotine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Taste | 1997 |
In vivo binding of [125I]NH2-carfentanil to mu opioid receptors in mouse brain.
Topics: Animals; Autoradiography; Brain; Fentanyl; Injections, Intraperitoneal; Iodine Radioisotopes; Logistic Models; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Radioligand Assay; Receptors, Opioid, mu | 1994 |
Evaluation of the safety and efficacy of deep sedation for electrophysiology procedures administered in the absence of an anesthetist.
Topics: Adjuvants, Anesthesia; Airway Obstruction; Anesthesia, Intravenous; Anesthesiology; Anesthetics, Intravenous; Blood Pressure; Consciousness; Cost Control; Electrocardiography; Electrophysiology; Evaluation Studies as Topic; Female; Fentanyl; Heart Rate; Humans; Hypnotics and Sedatives; Hypotension; Laboratories; Length of Stay; Male; Memory; Meperidine; Midazolam; Middle Aged; Monitoring, Physiologic; Naloxone; Narcotic Antagonists; Oximetry; Oxygen; Promethazine; Safety | 1997 |
Respiratory depression in a child unintentionally exposed to transdermal fentanyl patch.
Topics: Administration, Cutaneous; Analgesics, Opioid; Child, Preschool; Environmental Exposure; Fentanyl; Humans; Injections, Intravenous; Intubation, Intratracheal; Male; Naloxone; Narcotic Antagonists; Oxygen; Respiration; Respiration, Artificial; Respiratory Insufficiency; Sleep | 1997 |
Hypothermia associated with subarachnoid morphine.
Topics: Adult; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Body Temperature Regulation; Bupivacaine; Cesarean Section; Female; Fentanyl; Humans; Hypothermia; Morphine; Naloxone; Narcotic Antagonists; Nerve Block; Pregnancy; Subarachnoid Space | 1997 |
Transdermal fentanyl and respiratory depression.
Topics: Administration, Cutaneous; Analgesics, Opioid; Fentanyl; Humans; Naloxone; Narcotic Antagonists; Respiratory Insufficiency | 1997 |
Pharmacokinetic-pharmacodynamic modeling of the electroencephalogram effect of synthetic opioids in the rat: correlation with the interaction at the mu-opioid receptor.
Topics: Alfentanil; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Electroencephalography; Fentanyl; Male; Models, Biological; Naloxone; Rats; Rats, Wistar; Receptors, Opioid, mu; Sodium Chloride; Sufentanil | 1998 |
Kappa antinociceptive activity of spiradoline in the cold-water tail-flick assay in rats.
Topics: Analgesics; Analgesics, Opioid; Animals; Cold Temperature; Dose-Response Relationship, Drug; Drug Tolerance; Fentanyl; Male; Methadone; Naloxone; Narcotic Antagonists; Pain Measurement; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid, kappa; Stereoisomerism | 1998 |
Rapid opioid detoxification.
Topics: Adult; Drug Implants; Fentanyl; Humans; Male; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders | 1998 |
Interaction of the alpha-2 adrenergic- and opioid receptor with the cGMP system in the mouse cerebellum.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Opioid; Analysis of Variance; Animals; Cerebellum; Cyclic GMP; Fentanyl; Imidazoles; Male; Medetomidine; Mice; Naloxone; Narcotic Antagonists; Receptors, Adrenergic, alpha-2; Receptors, Opioid; Yohimbine | 1998 |
Tolerance and cross-tolerance to the rate-suppressing effects of opioids in butorphanol-treated rats: influence of maintenance dose and relative efficacy at the mu receptor.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Buprenorphine; Butorphanol; Dose-Response Relationship, Drug; Drug Tolerance; Fentanyl; Male; Naloxone; Phenobarbital; Rats; Rats, Long-Evans; Receptors, Opioid, mu; Sufentanil | 1998 |
Effect of fentanyl and naloxone on a thalamic induced painful response in intractable epileptic patients.
Topics: Adult; Analgesics, Opioid; Electric Stimulation Therapy; Electrocardiography; Electroencephalography; Electromyography; Epilepsy; Female; Fentanyl; Humans; Male; Naloxone; Narcotic Antagonists; Pain; Stereotaxic Techniques; Thalamus | 1998 |
Fentanyl and morphine, but not remifentanil, inhibit acetylcholine release in pontine regions modulating arousal.
Topics: Acetylcholine; Analgesics, Opioid; Animals; Arousal; Cats; Fentanyl; Male; Morphine; Naloxone; Piperidines; Pons; Remifentanil | 1999 |
Fentanyl analogues with a modified propanamido group as potential affinity labels: synthesis and in vivo activity.
Topics: Affinity Labels; Analgesics, Opioid; Animals; Fentanyl; Injections, Intraperitoneal; Magnetic Resonance Spectroscopy; Mice; Naloxone; Narcotic Antagonists; Pain Measurement; Spectrophotometry, Infrared | 1999 |
Modulation of emesis by fentanyl and opioid receptor antagonists in Suncus murinus (house musk shrew).
Topics: Animals; Antiemetics; Female; Fentanyl; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nicotine; Receptors, Opioid; Shrews; Vomiting | 1999 |
Differential binding properties of oripavines at cloned mu- and delta-opioid receptors.
Topics: Analgesics, Opioid; Animals; Benzamides; Binding, Competitive; Buprenorphine; Cloning, Molecular; Diprenorphine; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Etorphine; Fentanyl; Guanosine 5'-O-(3-Thiotriphosphate); Morphine; Naloxone; Piperazines; Radioligand Assay; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Sulfur Radioisotopes; Thebaine; Tritium; Tumor Cells, Cultured | 1999 |
Evidence for opiate-activated NMDA processes masking opiate analgesia in rats.
Topics: Analgesics, Opioid; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Fentanyl; Male; Morphine; Naloxone; Narcotic Antagonists; Nociceptors; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid | 1999 |
Effects of intracolonic opioid receptor agonists on polymodal pelvic nerve afferent fibers in the rat.
Topics: Acetamides; Analgesics; Analgesics, Opioid; Animals; Benzamides; Colon; Fentanyl; Hot Temperature; Male; Naloxone; Narcotic Antagonists; Nerve Fibers; Neurons, Afferent; Peripheral Nerves; Physical Stimulation; Piperazines; Pressure; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Spinal Nerve Roots | 2000 |
Homology models of mu-opioid receptor with organic and inorganic cations at conserved aspartates in the second and third transmembrane domains.
Topics: Amino Acid Sequence; Analgesics, Opioid; Animals; Aspartic Acid; Benzomorphans; Binding Sites; Cations; Cattle; Computer Simulation; Conserved Sequence; Fentanyl; Humans; Ligands; Metals; Models, Molecular; Molecular Sequence Data; Morphine; Naloxone; Narcotic Antagonists; Protein Binding; Protein Structure, Tertiary; Rats; Receptors, Opioid, mu; Sequence Alignment; Sequence Homology, Amino Acid; Structure-Activity Relationship | 2000 |
Fentanyl self-administration in juvenile rats that were tolerant and dependent to fentanyl as infants.
Topics: Animals; Drug Tolerance; Female; Fentanyl; Naloxone; Narcotics; Opioid-Related Disorders; Quinine; Rats; Rats, Sprague-Dawley; Self Administration | 2000 |
Effects of mu-opioid receptor agonists on intestinal secretion and permeability during acute intestinal inflammation in mice.
Topics: Acute Disease; Animals; Croton Oil; Dose-Response Relationship, Drug; Endorphins; Enteritis; Fentanyl; Intestinal Mucosa; Male; Mice; Morphine; Naloxone; Permeability; Receptors, Opioid, mu | 2000 |
Fentanyl-induced chest wall rigidity and laryngospasm in preterm and term infants.
Topics: Fentanyl; Humans; Hypercapnia; Hypoxia; Infant, Newborn; Infant, Premature; Laryngismus; Naloxone; Narcotic Antagonists; Narcotics; Prospective Studies; Respiratory Distress Syndrome, Newborn; Thoracic Diseases | 2000 |
Selectivity of mu-opioid receptor determined by interfacial residues near third extracellular loop.
Topics: Amino Acid Substitution; Animals; Benzamides; Benzomorphans; Binding Sites; Binding, Competitive; COS Cells; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Fentanyl; Guanosine 5'-O-(3-Thiotriphosphate); Ligands; Morphine; Mutation; Naloxone; Naltrexone; Narcotic Antagonists; Peptides; Piperazines; Protein Conformation; Radioligand Assay; Rats; Receptors, Opioid, mu; Signal Transduction; Sulfur Radioisotopes | 2000 |
Morphine suppresses complement receptor expression, phagocytosis, and respiratory burst in neutrophils by a nitric oxide and mu(3) opiate receptor-dependent mechanism.
Topics: Fentanyl; Flow Cytometry; Humans; In Vitro Techniques; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Neutrophils; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Phagocytosis; Receptors, Complement; Receptors, IgG; Receptors, Opioid, mu; Respiratory Burst; S-Nitroso-N-Acetylpenicillamine | 2000 |
Phenytoin, midazolam, and naloxone protect against fentanyl-induced brain damage in rats.
Topics: Analgesics, Opioid; Animals; Anticonvulsants; Blood Gas Analysis; Body Weight; Brain Diseases; Electroencephalography; Fentanyl; GABA Modulators; Male; Midazolam; Naloxone; Narcotic Antagonists; Phenytoin; Rats; Rats, Sprague-Dawley | 2000 |
Antinociceptive activity of the novel fentanyl analogue iso-carfentanil in rats.
Topics: Analgesics; Animals; Drug Interactions; Female; Fentanyl; Infusions, Parenteral; Male; Naloxone; Pain Measurement; Rats; Rats, Wistar; Structure-Activity Relationship; Time Factors | 2000 |
A murine model of opioid-induced hyperalgesia.
Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Fentanyl; Heme Oxygenase (Decyclizing); Hyperalgesia; Injections, Subcutaneous; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Naloxone; Narcotic Antagonists; Nitric Oxide Synthase; Pain Measurement; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu | 2001 |
The metabolic evidence of synergistic effect between ohmefentanyl and [D-Pen2, D-Pen5] enkephalin on differentiated SH-SY5Y cells in humans.
Topics: Acids; Analgesics; Analgesics, Opioid; Animals; Cell Differentiation; CHO Cells; Cricetinae; Drug Synergism; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Extracellular Space; Fentanyl; Humans; Naloxone; Narcotic Antagonists; Neuroblastoma; Neurons; Tumor Cells, Cultured | 2001 |
Nociceptin/orphanin FQ exacerbates excitotoxic white-matter lesions in the murine neonatal brain.
Topics: Animals; Animals, Newborn; Brain; Fentanyl; Humans; Ibotenic Acid; Infant, Newborn; Leukomalacia, Periventricular; Mice; Naloxone; Nociceptin; Oligonucleotides, Antisense; Opioid Peptides; Receptors, N-Methyl-D-Aspartate | 2001 |
Neural circuits regulating pulsatile luteinizing hormone release in the female guinea-pig: opioid, adrenergic and serotonergic interactions.
Topics: Animals; Clonidine; Drug Interactions; Female; Fentanyl; Gonadotropin-Releasing Hormone; Guinea Pigs; Luteinizing Hormone; Methysergide; Naloxone; Norepinephrine; Opioid Peptides; Ovariectomy; Periodicity; Quipazine; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Yohimbine | 2001 |
Opiate self-administration as a measure of chronic nociceptive pain in arthritic rats.
Topics: Analgesics, Opioid; Animals; Arthritis; Behavior, Animal; Chronic Disease; Fentanyl; Male; Naloxone; Narcotic Antagonists; Narcotics; Nociceptors; Pain; Pain Measurement; Palliative Care; Rats; Rats, Inbred Lew; Reference Values; Self Administration; Substance-Related Disorders; Time Factors | 2001 |
Evidence for mu opioid receptor on mouse spleen lymphocytes.
Topics: Animals; Cell Division; Female; Fentanyl; Mice; Mice, Inbred ICR; Naloxone; Receptors, Opioid, mu; Spleen; T-Lymphocytes | 1999 |
Cannabinoidergic and opioidergic inhibition of spinal reflexes in the decerebrated, spinalized rabbit.
Topics: Animals; Decerebrate State; Dose-Response Relationship, Drug; Dronabinol; Female; Fentanyl; Male; Naloxone; Narcotic Antagonists; Piperidines; Pyrazoles; Rabbits; Receptors, Cannabinoid; Receptors, Drug; Reflex; Rimonabant; Spinal Cord; Spinal Cord Injuries | 2001 |
Anxiogenic-like effects of opiate withdrawal seen in the fear-potentiated startle test, an interdisciplinary probe for drug-related motivational states.
Topics: Acoustic Stimulation; Analgesics, Opioid; Animals; Anxiety; Behavior, Animal; Body Weight; Fear; Fentanyl; Injections, Intraventricular; Male; Motivation; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Reflex, Startle; Substance Withdrawal Syndrome | 2001 |
Modulation of breathing by mu1 and mu2 opioid receptor stimulation in neonatal and adult rats.
Topics: Age Factors; Analgesics, Opioid; Animals; Animals, Newborn; Female; Fentanyl; Lung; Male; Naloxone; Oligopeptides; Opioid Peptides; Rats; Rats, Wistar; Receptors, Opioid, mu; Respiratory Mechanics; Tidal Volume | 2001 |
Effects of adolescent nicotine exposure on opioid consumption and neuroendocrine responses in adult male and female rats.
Topics: Adrenocorticotropic Hormone; Aging; Analgesics, Opioid; Animals; Body Weight; Corticosterone; Drinking; Eating; Female; Fentanyl; Male; Naloxone; Narcotic Antagonists; Neurosecretory Systems; Nicotine; Nicotinic Agonists; Opioid-Related Disorders; Rats; Rats, Wistar; Sex Characteristics; Substance Withdrawal Syndrome | 2001 |
Subeffective doses of dexketoprofen trometamol enhance the potency and duration of fentanyl antinociception.
Topics: Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Fentanyl; Ketoprofen; Male; Naloxone; Narcotic Antagonists; Pain Measurement; Rats; Rats, Wistar; Tromethamine | 2002 |
[Effects of fentanyl on acetylcholine release from hippocampus and righting reflex in rat: an in vivo brain microdialysis study].
Topics: Acetylcholine; Analgesics, Opioid; Animals; Fentanyl; Hippocampus; Male; Microdialysis; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Reflex | 2002 |
mu-1 opioid receptor stimulation decreases body temperature in conscious, unrestrained neonatal rats.
Topics: Analgesics, Opioid; Animals; Animals, Newborn; Body Temperature; Female; Fentanyl; Male; Naloxone; Oligopeptides; Opioid Peptides; Rats; Rats, Wistar; Receptors, Opioid, mu; Temperature; Time Factors | 2002 |
[Opioid intoxication following transdermal administration of fentanyl].
Topics: Administration, Cutaneous; Aged; Analgesics, Opioid; Female; Fentanyl; Humans; Medication Errors; Naloxone; Narcotic Antagonists | 2002 |
Possible involvement of mu1-opioid receptors in the fentanyl- or morphine-induced antinociception at supraspinal and spinal sites.
Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Fentanyl; Injections, Intraventricular; Injections, Spinal; Injections, Subcutaneous; Male; Mice; Mice, Inbred C57BL; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Receptors, Opioid, mu; Spinal Cord | 2002 |
Fentanyl-induced rigidity during emergence from general anesthesia potentiated by venlafexine.
Topics: Adult; Analgesics, Opioid; Anesthesia Recovery Period; Anesthesia, General; Antidepressive Agents, Second-Generation; Cyclohexanols; Drug Synergism; Female; Fentanyl; Humans; Muscle Rigidity; Naloxone; Narcotic Antagonists; Venlafaxine Hydrochloride | 2003 |
Internalization and recycling of human mu opioid receptors expressed in Sf9 insect cells.
Topics: Analgesics, Opioid; Animals; Cell Line; Cyclic AMP; Dose-Response Relationship, Drug; Down-Regulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Fentanyl; Humans; Hypertonic Solutions; Insecta; Microscopy, Confocal; Morphine; Naloxone; Narcotic Antagonists; Pertussis Toxin; Receptors, Cell Surface; Receptors, Opioid, mu; Transfection | 2003 |
Use of naloxone to reverse carfentanil citrate-induced hypoxemia and cardiopulmonary depression in Rocky Mountain wapiti (Cervus elaphus nelsoni).
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Blood Gas Analysis; Cross-Over Studies; Deer; Electrocardiography; Female; Fentanyl; Heart Rate; Hypoxia; Naloxone; Narcotic Antagonists; Oximetry; Oxygen; Partial Pressure; Respiration; Xylazine | 2001 |
Chemical anesthesia of northern sea otters (Enhydra lutris): results of past field studies.
Topics: Anesthesia; Anesthetics, Combined; Anesthetics, Intravenous; Animals; Azaperone; Body Temperature; Diazepam; Female; Fentanyl; Heart Rate; Hypnotics and Sedatives; Immobilization; Logistic Models; Male; Naloxone; Naltrexone; Narcotic Antagonists; Otters; Respiration; Seizures; Time Factors; Tremor | 2001 |
Human immobilization: is the experience in Moscow just the beginning?
Topics: Adult; Aerosols; Analgesics, Opioid; Fentanyl; Humans; Immobilization; Moscow; Naloxone; Narcotic Antagonists; Terrorism | 2003 |
5-HT4(a) receptors avert opioid-induced breathing depression without loss of analgesia.
Topics: Analgesics, Opioid; Animals; Benzimidazoles; Brain Stem; Bridged Bicyclo Compounds, Heterocyclic; Cyclic AMP; Fentanyl; In Vitro Techniques; Interneurons; Medulla Oblongata; Naloxone; Neurons; Pain Measurement; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Opioid, mu; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Respiration; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin Receptor Agonists; Signal Transduction; Spinal Cord | 2003 |
Systemic morphine-induced release of serotonin in the rostroventral medulla is not mimicked by morphine microinjection into the periaqueductal gray.
Topics: Analgesics, Opioid; Animals; Drug Administration Routes; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Fentanyl; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Medulla Oblongata; Microdialysis; Microinjections; Morphine; Naloxone; Narcotic Antagonists; Pain Measurement; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Serotonin; Substance Withdrawal Syndrome; Wakefulness | 2003 |
Effects of ohmefentanyl stereoisomers on phosphorylation of cAMP- response element binding protein in cultured rat hippocampal neurons.
Topics: Analgesics; Animals; Cells, Cultured; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Fentanyl; Hippocampus; Morphine; Naloxone; Neurons; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Signal Transduction; Stereoisomerism | 2003 |
G-protein receptor kinase 3 (GRK3) influences opioid analgesic tolerance but not opioid withdrawal.
Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Implants; Drug Tolerance; Electrophysiology; Evoked Potentials; Fentanyl; G-Protein-Coupled Receptor Kinase 3; Hippocampus; Homozygote; Hot Temperature; Infusion Pumps, Implantable; Injections, Subcutaneous; Male; Mice; Mice, Knockout; Morphine; Naloxone; Pain Measurement; Protein Serine-Threonine Kinases; Reaction Time; Receptors, Opioid; Substance Withdrawal Syndrome; Up-Regulation | 2004 |
The fentanyl tea bag.
Topics: Adult; Beverages; Diagnosis, Differential; Drug Overdose; Emergency Treatment; Female; Fentanyl; Humans; Infusions, Intravenous; Naloxone; Narcotic Antagonists; Narcotics | 2004 |
Naloxone reversal of opioid anesthesia revisited: clinical evaluation and plasma concentration analysis of continuous naloxone infusion after anesthesia with high-dose fentanyl.
Topics: Abdomen; Analgesics, Opioid; Anesthetics, Intravenous; Depression, Chemical; Female; Fentanyl; Humans; Infusion Pumps; Infusions, Intravenous; Male; Middle Aged; Naloxone; Narcotic Antagonists; Pain Measurement; Respiration; Respiration, Artificial | 2004 |
Effect of chronic treatment of ohmefentanyl stereoisomers on cyclic AMP formation in Sf9 insect cells expressing human mu-opioid receptors.
Topics: Analgesics; Animals; Binding, Competitive; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Drug Combinations; Fentanyl; Humans; Mice; Morphine Dependence; Naloxone; Receptors, Opioid, mu; Spodoptera; Stereoisomerism; Transfection | 2004 |
Severe withdrawal from short-term transdermal fentanyl after naloxone for uremic pruritus.
Topics: Administration, Cutaneous; Analgesics, Opioid; Drug Interactions; Drug Therapy, Combination; Fentanyl; Humans; Male; Middle Aged; Naloxone; Narcotic Antagonists; Pain; Pruritus; Substance Withdrawal Syndrome; Uremia; Withholding Treatment | 2004 |
Inhibitory effect of fentanyl on acetylcholine-induced relaxation in rat aorta.
Topics: Acetylcholine; Analgesics, Opioid; Animals; Aorta, Thoracic; Calcimycin; Dose-Response Relationship, Drug; Fentanyl; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Relaxation; Muscle, Smooth, Vascular; Naloxone; Narcotic Antagonists; Phenylephrine; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Vasoconstrictor Agents; Vasodilator Agents | 2004 |
Modulation of extracellular signal-regulated kinase (ERK) activity by acute and chronic opioid treatment in neuronal and glial cell lines.
Topics: Animals; Blotting, Western; Cell Line, Tumor; Diprenorphine; Drug Administration Schedule; Enzyme Activation; Fentanyl; Glioma; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ligands; Mitogen-Activated Protein Kinases; Naloxone; Narcotic Antagonists; Narcotics; Neuroblastoma; Neuroglia; Neurons; Radioligand Assay; Rats; Time Factors | 2004 |
Fentanyl patch abuse: naloxone complications and extracorporeal membrane oxygenation rescue.
Topics: Adult; Extracorporeal Membrane Oxygenation; Fentanyl; Humans; Insufflation; Male; Naloxone; Narcotic Antagonists; Narcotics; Respiratory Insufficiency; Substance-Related Disorders; Treatment Outcome | 2004 |
Ancient gill and lung oscillators may generate the respiratory rhythm of frogs and rats.
Topics: Action Potentials; Analysis of Variance; Animals; Biological Clocks; Brain Stem; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Fentanyl; Gills; Hypercapnia; In Vitro Techniques; Larva; Lung; Male; Models, Biological; Naloxone; Narcotic Antagonists; Narcotics; Nerve Net; Periodicity; Photoplethysmography; Physical Conditioning, Animal; Ranidae; Rats; Rats, Wistar; Respiration; Respiratory Physiological Phenomena; Vagotomy | 2005 |
[Increasing importance of opioids in geriatrics].
Topics: Aged; Analgesics, Opioid; Costs and Cost Analysis; Drug Prescriptions; Fentanyl; Geriatrics; Germany; Humans; Morphine; Naloxone; Oxycodone; Tramadol | 2005 |
Effect of fentanyl on lidocaine-induced convulsions in mice.
Topics: Animals; Dose-Response Relationship, Drug; Drug Synergism; Fentanyl; Injections, Intraperitoneal; Lidocaine; Male; Mice; Mice, Inbred ICR; Naloxone; Narcotic Antagonists; Narcotics; Preanesthetic Medication; Seizures | 2005 |
Severe deficit in brain reward function associated with fentanyl withdrawal in rats.
Topics: Affect; Animals; Brain; Dose-Response Relationship, Drug; Fentanyl; Male; Medial Forebrain Bundle; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Rats; Rats, Wistar; Reaction Time; Receptors, Opioid, mu; Reward; Self Stimulation; Sensory Thresholds; Substance Withdrawal Syndrome | 2006 |
Prolonged recovery and respiratory depression after fentanyl infusion in a sheep undergoing mitral valve reconstruction.
Topics: Anesthesia Recovery Period; Anesthetics, Intravenous; Animals; Female; Fentanyl; Mitral Valve Insufficiency; Naloxone; Narcotic Antagonists; Respiratory Insufficiency; Sheep; Sheep Diseases | 2005 |
Distinct rhythm generators for inspiration and expiration in the juvenile rat.
Topics: Aging; Animals; Biological Clocks; Decerebrate State; Exhalation; Female; Fentanyl; Inhalation; Lung; Male; Mesencephalon; Motor Neurons; Naloxone; Periodicity; Pons; Rats; Rats, Sprague-Dawley; Respiratory Function Tests; Respiratory Mechanics; Respiratory Muscles; Vagotomy; Vagus Nerve | 2006 |
[Prolonged respiratory depression after fentanyl administration in a patient with mitochondrial encephalomyopathy].
Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Cysts; Fentanyl; Humans; Infusions, Intravenous; Male; Maxillary Diseases; Mitochondrial Encephalomyopathies; Naloxone; Respiratory Insufficiency | 2006 |
Blocking mu opioid receptors in the spinal cord prevents the analgesic action by subsequent systemic opioids.
Topics: Analgesics; Analysis of Variance; Animals; Behavior, Animal; Drug Interactions; Fentanyl; Male; Naloxone; Narcotic Antagonists; Narcotics; Pain Measurement; Peptide Fragments; Peptides; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid; Somatostatin; Spinal Cord; Time Factors | 2006 |
Synthesis and pharmacological studies of new hybrid derivatives of fentanyl active at the mu-opioid receptor and I2-imidazoline binding sites.
Topics: Analgesics, Opioid; Animals; Binding Sites; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Fentanyl; Guanidine; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Imidazoline Receptors; In Vitro Techniques; Indicators and Reagents; Male; Membranes; Mice; Naloxone; Narcotic Antagonists; Pain Measurement; Prefrontal Cortex; Reaction Time; Receptors, Drug; Receptors, Opioid, mu; Structure-Activity Relationship | 2006 |
Mixed opioid--mixed message?
Topics: Aged; Analgesics, Opioid; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Intravenous; Female; Fentanyl; Humans; Morphine; Naloxone; Narcotic Antagonists; Propofol; Receptors, Opioid, mu | 2006 |
Mu opioid receptor activation of ERK1/2 is GRK3 and arrestin dependent in striatal neurons.
Topics: Animals; Arrestins; beta-Adrenergic Receptor Kinases; Cells, Cultured; Corpus Striatum; Enzyme Activation; Fentanyl; G-Protein-Coupled Receptor Kinase 3; Immunoblotting; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Naloxone; Narcotic Antagonists; Neurons; Phosphorylation; Receptors, Opioid, mu; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Transfection | 2006 |
Pharmacologic evidence for the involvement of central and peripheral opioid receptors in the cardioprotective effects of fentanyl.
Topics: Animals; Arrhythmias, Cardiac; Cardiotonic Agents; Dose-Response Relationship, Drug; Female; Fentanyl; Hemodynamics; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Naloxone; Narcotic Antagonists; Rabbits; Receptors, Opioid | 2006 |
The neural cell adhesion molecule antibody blocks cold water swim stress-induced analgesia and cell adhesion between lymphocytes and cultured dorsal root ganglion neurons.
Topics: Analgesia; Animals; Antibodies, Monoclonal; beta-Endorphin; Cell Adhesion; Cells, Cultured; Fentanyl; Ganglia, Spinal; Intercellular Adhesion Molecule-1; Lymphocytes; Male; Naloxone; Neural Cell Adhesion Molecules; Rats; Rats, Wistar; Stress, Psychological; Swimming | 2006 |
The effects of buprenorphine on fentanyl withdrawal in rats.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Buprenorphine; Disease Models, Animal; Dose-Response Relationship, Drug; Emotions; Fentanyl; Male; Naloxone; Narcotic Antagonists; Narcotics; Rats; Rats, Wistar; Receptors, Opioid, mu; Reward; Substance Withdrawal Syndrome; Time Factors | 2007 |
Naloxone antagonizes the local antihyperalgesic effect of fentanyl in burnt skin of healthy humans.
Topics: Adolescent; Adult; Analgesics, Opioid; Burns; Dose-Response Relationship, Drug; Female; Fentanyl; Humans; Hyperalgesia; Male; Naloxone; Narcotic Antagonists; Nociceptors; Pain Measurement; Pain Threshold; Receptors, Opioid; Sensory Receptor Cells; Skin | 2007 |
Thanks for the high.
Topics: Emergency Medical Services; Fentanyl; Humans; Naloxone; Substance-Related Disorders; United States | 2007 |
A sticky situation: toxicity of clonidine and fentanyl transdermal patches in pediatrics.
Topics: Accidents; Administration, Cutaneous; Analgesics, Opioid; Antihypertensive Agents; Clonidine; Coma; Drug Overdose; Emergency Treatment; Fentanyl; Humans; Infant; Naloxone; Narcotic Antagonists; Patient Education as Topic; Seizures; Self Administration | 2007 |
The impact of the opioids fentanyl and morphine on nociception and bone destruction in a murine model of bone cancer pain.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Body Weight; Bone and Bones; Bone Neoplasms; Femur; Fentanyl; Male; Mice; Mice, Inbred C3H; Morphine; Naloxone; Narcotic Antagonists; Neoplasm Transplantation; Osteosarcoma; Pain Measurement; Pain, Intractable; Postural Balance; Tomography, X-Ray Computed; Tumor Cells, Cultured | 2007 |
Loss of gag reflex and swallowing ability after administration of intrathecal fentanyl.
Topics: Adult; Analgesia, Obstetrical; Analgesics, Opioid; Deglutition Disorders; Female; Fentanyl; Gagging; Humans; Injections, Spinal; Naloxone; Narcotic Antagonists; Pregnancy | 2007 |
[Accidental intoxication with unlabeled, generic transdermal fentanyl patches caused by insufficient instruction].
Topics: Administration, Cutaneous; Aged; Analgesics, Opioid; Drugs, Generic; Electrocardiography; Emergency Medical Services; Fentanyl; Humans; Infusions, Intravenous; Male; Naloxone; Narcotic Antagonists; Stroke | 2007 |
Naloxone reversal of opioid-induced respiratory depression with special emphasis on the partial agonist/antagonist buprenorphine.
Topics: Alfentanil; Analgesics, Opioid; Animals; Buprenorphine; Dose-Response Relationship, Drug; Fentanyl; Humans; Morphine; Naloxone; Rats; Respiratory Mechanics | 2008 |
[Remifentanil bolus for cesarean section in high-risk patients: study of 12 cases].
Topics: Adult; Anesthetics, Intravenous; Atracurium; Cesarean Section; Female; Fentanyl; Fetus; Hemodynamics; Humans; Infant, Newborn; Methyl Ethers; Muscle Rigidity; Naloxone; Nitrous Oxide; Piperidines; Pregnancy; Pregnancy Complications; Pregnancy, High-Risk; Propofol; Remifentanil; Resuscitation; Retrospective Studies; Sevoflurane; Succinylcholine | 2008 |
Sex versus sweet: opposite effects of opioid drugs on the reward of sucrose and sexual pheromones.
Topics: Animals; Choice Behavior; Conditioning, Classical; Exploratory Behavior; Female; Fentanyl; Male; Mice; Naloxone; Narcotic Antagonists; Narcotics; Reward; Sex Attractants; Smell; Sucrose; Taste | 2008 |
Morphine, opioids, and the feline pulmonary vascular bed.
Topics: Analgesics, Opioid; Animals; Blood Pressure; Cats; Diphenhydramine; Dose-Response Relationship, Drug; Drug Interactions; Female; Fentanyl; Glyburide; Lung; Male; Meperidine; Morphine; Naloxone; Ornithine; Piperidines; Prospective Studies; Pulmonary Artery; Pulmonary Circulation; Remifentanil; Sufentanil; Sulfonamides; Vasodilation; Vasodilator Agents | 2008 |
Fentanyl epidemic in Chicago, Illinois and surrounding Cook County.
Topics: Adult; Cause of Death; Coroners and Medical Examiners; Databases, Factual; Drug Overdose; Emergency Service, Hospital; Female; Fentanyl; Forensic Toxicology; Humans; Illicit Drugs; Illinois; Male; Middle Aged; Naloxone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Retrospective Studies; Transportation of Patients | 2008 |
Effects of fentanyl dose and exposure duration on the affective and somatic signs of fentanyl withdrawal in rats.
Topics: Affective Symptoms; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Fentanyl; Male; Naloxone; Narcotic Antagonists; Narcotics; Rats; Rats, Wistar; Reward; Self Administration; Substance Withdrawal Syndrome; Time Factors | 2008 |
Involvement of kappa-opioid receptors in visceral nociception in mice.
Topics: Analgesics, Opioid; Animals; Colon; Dilatation, Pathologic; Electromyography; Female; Fentanyl; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Naloxone; Narcotic Antagonists; Nociceptors; Pain; Pain Measurement; Receptors, Opioid, kappa; Receptors, Opioid, mu; Rectum | 2008 |
Analgesic activity and pharmacological characterization of N-[1-phenylpyrazol-3-yl]-N-[1-(2-phenethyl)-4-piperidyl] propenamide, a new opioid agonist acting peripherally.
Topics: Administration, Oral; Analgesics, Opioid; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Fentanyl; Guinea Pigs; Hot Temperature; Ileum; Injections, Intraperitoneal; Injections, Intraventricular; Male; Mice; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Pain; Pain Measurement; Pain Threshold; Piperidines; Propane; Quaternary Ammonium Compounds; Reaction Time; Substance Withdrawal Syndrome; Time Factors | 2008 |
Competitive substrates for P-glycoprotein and organic anion protein transporters differentially reduce blood organ transport of fentanyl and loperamide: pharmacokinetics and pharmacodynamics in Sprague-Dawley rats.
Topics: Analgesics, Opioid; Animals; ATP Binding Cassette Transporter, Subfamily B; Binding, Competitive; Brain; Electroencephalography; Fentanyl; Infusions, Intravenous; Loperamide; Lung; Male; Models, Biological; Naloxone; Organic Anion Transporters; Pravastatin; Rats; Rats, Sprague-Dawley; Tissue Distribution; Verapamil | 2009 |
Effects of sevoflurane on carrageenan- and fentanyl-induced pain hypersensitivity in Sprague-Dawley rats.
Topics: Analgesics, Opioid; Anesthetics, Inhalation; Animals; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Fentanyl; Hyperalgesia; Male; Methyl Ethers; Naloxone; Narcotic Antagonists; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sevoflurane | 2009 |
Safety of enteral naloxone for the reversal of opiate-induced constipation in the intensive care unit.
Topics: Aged; Analgesics, Opioid; Constipation; Critical Care; Female; Fentanyl; Humans; Intubation, Gastrointestinal; Liver Function Tests; Male; Middle Aged; Naloxone; Narcotic Antagonists; Pain; Pain Measurement | 2009 |
Naloxone-induced pulmonary edema: a potential cause of postoperative morbidity in laparoscopic donor nephrectomy.
Topics: Adult; Analgesics, Opioid; Fentanyl; Humans; Laparoscopy; Male; Naloxone; Narcotic Antagonists; Nephrectomy; Positive-Pressure Respiration; Postoperative Complications; Pulmonary Edema; Tissue Donors | 2009 |
Identification of an additional supraspinal component to the analgesic mechanism of action of buprenorphine.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Aminoquinolines; Analgesics, Opioid; Anesthetics, Local; Animals; Benzamides; Brain; Buprenorphine; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fentanyl; GTP-Binding Proteins; Injections, Intraventricular; Injections, Spinal; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; Nociceptin; Nociceptin Receptor; Okadaic Acid; Oligonucleotides, Antisense; Opioid Peptides; Pain; Pain Measurement; Pain Threshold; Pertussis Toxin; Phosphoprotein Phosphatases; Piperazines; Pyridines; Receptor, Serotonin, 5-HT1A; Receptors, Opioid; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists; Signal Transduction; Yohimbine | 2009 |
Behavioral depression induced by an amygdala seizure and the opioid fentanyl was mediated through the nucleus accumbens.
Topics: Amygdala; Analysis of Variance; Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Electric Stimulation; Electroencephalography; Fentanyl; Functional Laterality; Kindling, Neurologic; Male; Naloxone; Narcotic Antagonists; Narcotics; Nucleus Accumbens; Rats; Rats, Long-Evans; Reflex; Seizures; Statistics, Nonparametric | 2009 |
Respiratory arrest after cadaveric renal transplant.
Topics: Adult; Analgesics, Opioid; Cadaver; Fentanyl; Humans; Kidney Transplantation; Male; Naloxone; Narcotic Antagonists; Respiratory Insufficiency | 2009 |
Interaction of morphine but not fentanyl with cerebral alpha2-adrenoceptors in alpha2-adrenoceptor knockout mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Animals; Autoradiography; Binding, Competitive; Brain; Clonidine; Drug Partial Agonism; Female; Fentanyl; In Vitro Techniques; Male; Mice; Mice, Knockout; Morphine; Naloxone; Radioligand Assay; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu | 2009 |
Fentanyl inhibits glucose-stimulated insulin release from beta-cells in rat pancreatic islets.
Topics: Analgesics, Opioid; Animals; Fentanyl; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Naloxone; Rats; Rats, Sprague-Dawley | 2009 |
Morphine-induced muscle rigidity in a term neonate.
Topics: Analgesics, Opioid; Fentanyl; Humans; Infant, Newborn; Male; Morphine; Muscle Rigidity; Naloxone; Narcotic Antagonists; Propofol | 2009 |
Characterization of scratching behavior induced by intradermal administration of morphine and fentanyl in mice.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Fentanyl; Histamine H1 Antagonists; Hypnotics and Sedatives; Injections, Intradermal; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Narcotic Antagonists; Pruritus; Receptors, Opioid | 2010 |
Case of chest-wall rigidity in a preterm infant caused by prenatal fentanyl administration.
Topics: Cesarean Section; Female; Fentanyl; Humans; Infant, Newborn; Infant, Premature, Diseases; Muscle Rigidity; Naloxone; Narcotic Antagonists; Narcotics; Pregnancy; Pregnancy Complications, Infectious; Pyelonephritis; Respiratory Distress Syndrome; Thoracic Wall | 2010 |
Histamine H3 receptor activation potentiates peripheral opioid-mediated antinociception: substance P role in peripheral inflammation in mice.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Fentanyl; Freund's Adjuvant; Histamine Agonists; Hyperalgesia; Inflammation; Male; Methylhistamines; Mice; Naloxone; Pain; Piperidines; Receptors, Histamine H3; Skin; Substance P | 2010 |
Complications of oral exposure to fentanyl transdermal delivery system patches.
Topics: Administration, Oral; Adult; Analgesics, Opioid; Databases, Factual; Female; Fentanyl; Humans; Male; Middle Aged; Naloxone; Narcotic Antagonists; Poisoning; Respiration, Artificial; Substance-Related Disorders; Suicide, Attempted; Transdermal Patch; Treatment Outcome | 2010 |
L-type calcium channels and μ-opioid receptors are involved in mediating the anti-inflammatory effects of naloxone.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anti-Inflammatory Agents; Calcium Channels, L-Type; Cell Line; Chemokine CXCL2; Fentanyl; Inflammation; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Macrophages; Mice; Models, Animal; Morphine; Naloxone; NF-kappa B; Receptors, Opioid, mu | 2011 |
The role of beta-arrestin2 in the severity of antinociceptive tolerance and physical dependence induced by different opioid pain therapeutics.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Arrestins; beta-Arrestins; Drug Tolerance; Fentanyl; Hot Temperature; Male; Methadone; Mice; Mice, Knockout; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Oxycodone; Pain; Pain Measurement; Pain Threshold; Receptors, Opioid, mu | 2011 |
Negative pressure pulmonary edema following naloxone administration in a patient with fentanyl-induced respiratory depression.
Topics: Fentanyl; Humans; Male; Naloxone; Narcotic Antagonists; Pulmonary Edema; Respiratory Insufficiency; Sleep Apnea, Obstructive; Young Adult | 2010 |
Inhibition of motility in isolated horse small intestine is mediated by κ but not µ opioid receptors.
Topics: Analgesics, Opioid; Animals; Benzeneacetamides; Dose-Response Relationship, Drug; Fentanyl; Gastrointestinal Motility; Horses; Intestine, Small; Male; Morphine; Naloxone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2012 |
Effects of airway occlusion on breathing muscle electromyogram signals, during isoflurane anaesthesia, with and without the effects of fentanyl and hypercapnia.
Topics: Abdominal Muscles; Adult; Aged; Airway Obstruction; Analgesics, Opioid; Anesthetics, Inhalation; Carbon Dioxide; Child; Electromyography; Female; Fentanyl; Humans; Hypercapnia; Isoflurane; Male; Middle Aged; Naloxone; Nitrous Oxide; Respiratory Muscles | 2011 |
Opioid binding sites in human serum albumin.
Topics: Analgesics, Opioid; Anesthetics, Intravenous; Binding Sites; Binding, Competitive; Calorimetry; Chromatography, Affinity; Fentanyl; Humans; Models, Molecular; Morphine; Naloxone; Narcotic Antagonists; Propofol; Protein Binding; Protein Conformation; Serum Albumin; Spectrometry, Fluorescence | 2012 |
The response to rapid infusion of fentanyl in the human brain measured using pulsed arterial spin labelling.
Topics: Adult; Analgesics, Opioid; Brain; Cerebral Arteries; Cerebrovascular Circulation; Echo-Planar Imaging; Fentanyl; Heart Rate; Humans; Infusions, Intravenous; Male; Naloxone; Perfusion Imaging; Regional Blood Flow; Reproducibility of Results; Spin Labels | 2012 |
Crosstalk between cdk5 and MEK-ERK signalling upon opioid receptor stimulation leads to upregulation of activator p25 and MEK1 inhibition in rat brain.
Topics: Analysis of Variance; Animals; Benzamides; Brain; Cyclin-Dependent Kinase 5; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Fentanyl; Gene Expression Regulation; Male; MAP Kinase Kinase 1; Naloxone; Narcotic Antagonists; Narcotics; Phosphorylation; Phosphotransferases; Piperazines; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Time Factors; Up-Regulation | 2012 |
Transdermal fentanyl in deliberate overdose in pediatrics.
Topics: Administration, Cutaneous; Adolescent; Analgesics, Opioid; Dose-Response Relationship, Drug; Drug Overdose; Female; Fentanyl; Humans; Infusions, Intravenous; Naloxone; Narcotic Antagonists; Self-Injurious Behavior; Suicide, Attempted | 2012 |
Chest wall rigidity in two infants after low-dose fentanyl administration.
Topics: Analgesics, Opioid; Dose-Response Relationship, Drug; Female; Fentanyl; Follow-Up Studies; Humans; Hypercapnia; Infant; Infant, Newborn; Injections, Intravenous; Muscle Rigidity; Naloxone; Narcotic Antagonists; Thoracic Wall | 2012 |
[Life-threatening fentanyl and propofol addiction: interview with a survivor].
Topics: Adult; Analgesics, Opioid; Anesthesiology; Anesthetics, Intravenous; Female; Fentanyl; Humans; Naloxone; Opioid-Related Disorders; Physician Impairment; Physicians; Prescription Drug Diversion; Propofol; Substance Abuse, Intravenous; Substance-Related Disorders; Survivors; Tilidine | 2012 |
The relationship between naloxone-induced cortisol and mu opioid receptor availability in mesolimbic structures is disrupted in alcohol dependent subjects.
Topics: Adult; Alcoholism; Carbon Radioisotopes; Female; Fentanyl; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Middle Aged; Naloxone; Narcotic Antagonists; Pituitary-Adrenal System; Positron-Emission Tomography; Receptors, Opioid, mu | 2012 |
Fatal overdose after ingestion of a transdermal fentanyl patch in two non-human primates.
Topics: Administration, Cutaneous; Analgesics, Opioid; Animals; Drug Overdose; Fentanyl; Macaca fascicularis; Male; Naloxone; Narcotic Antagonists | 2012 |
MicroRNA 339 down-regulates μ-opioid receptor at the post-transcriptional level in response to opioid treatment.
Topics: 3' Untranslated Regions; Analgesics, Opioid; Animals; Base Sequence; Cell Line; Down-Regulation; Fentanyl; HEK293 Cells; Hippocampus; Humans; Mice; MicroRNAs; Morphine; Naloxone; Narcotic Antagonists; Promoter Regions, Genetic; Receptors, Opioid, mu; RNA Processing, Post-Transcriptional; RNA Stability; RNA, Messenger; Up-Regulation | 2013 |
Involvement of spinal orexin A in the electroacupuncture analgesia in a rat model of post-laparotomy pain.
Topics: Abdomen; Acupuncture Points; Analgesia; Animals; Electroacupuncture; Fentanyl; Hindlimb; Hyperalgesia; Intracellular Signaling Peptides and Proteins; Laparotomy; Male; Naloxone; Narcotic Antagonists; Neuropeptides; Orexin Receptors; Orexins; Pain; Pain Management; Postoperative Complications; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Spine | 2012 |
Fentanyl-induced chest wall rigidity.
Topics: Aged; Analgesics, Opioid; Bronchoscopy; Fentanyl; Humans; Male; Muscle Rigidity; Naloxone; Narcotic Antagonists; Thoracic Wall; Treatment Outcome | 2013 |
Morphine and fentanyl differently affect MOP and NOP gene expression in human neuroblastoma SH-SY5Y cells.
Topics: Cell Line, Tumor; Fentanyl; Humans; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Neuroblastoma; Nociceptin Receptor; Receptors, Opioid; Receptors, Opioid, mu; RNA, Messenger; Transcription, Genetic | 2013 |
Novel fentanyl-based dual μ/δ-opioid agonists for the treatment of acute and chronic pain.
Topics: Acute Pain; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chronic Pain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enkephalins; Fentanyl; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu | 2013 |
Role of central and peripheral opiate receptors in the effects of fentanyl on analgesia, ventilation and arterial blood-gas chemistry in conscious rats.
Topics: Analysis of Variance; Animals; Blood Gas Analysis; Blood Pressure; Body Temperature; Consciousness; Fentanyl; Hyperalgesia; Male; Naloxone; Narcotic Antagonists; Narcotics; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Reaction Time; Respiration; Tidal Volume | 2014 |
Glial TLR4 signaling does not contribute to opioid-induced depression of respiration.
Topics: Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Female; Fentanyl; Male; Medulla Oblongata; Minocycline; Naloxone; Neuroglia; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Respiration; Respiratory Insufficiency; Signal Transduction; Toll-Like Receptor 4 | 2014 |
Successful management of drug-induced hypercapnic acidosis with naloxone and noninvasive positive pressure ventilation.
Topics: Acidosis; Aged; Analgesics, Opioid; Combined Modality Therapy; Fentanyl; Humans; Hypercapnia; Male; Naloxone; Narcotic Antagonists; Positive-Pressure Respiration; Tramadol | 2015 |
Interaction of the adenosine A1 receptor agonist N6-cyclopentyladenosine and κ-opioid receptors in rat spinal cord nociceptive reflexes.
Topics: Adenosine; Animals; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Fentanyl; Inflammation; Male; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Rats; Rats, Wistar; Receptors, Opioid, kappa; Reflex; Spinal Cord | 2014 |
Risk Factors and Outcomes of Reversal Agent Use in Moderate Sedation During Endoscopy and Colonoscopy.
Topics: Age Factors; Anti-Arrhythmia Agents; Antidotes; Atropine; Body Mass Index; Bradycardia; Case-Control Studies; Colonoscopy; Conscious Sedation; Female; Fentanyl; Flumazenil; Health Status; Humans; Hypnotics and Sedatives; Hypotension; Hypoxia; Male; Midazolam; Middle Aged; Naloxone; Narcotic Antagonists; Sex Factors; Treatment Outcome | 2016 |
Life-threatening opioid toxicity from a fentanyl patch applied to eczematous skin.
Topics: Administration, Cutaneous; Analgesics, Opioid; Eczema; Fentanyl; Humans; Male; Naloxone; Narcotic Antagonists; Self Medication; Transdermal Patch; Young Adult | 2015 |
Reversal of overdose on fentanyl being illicitly sold as heroin with naloxone nasal spray: A case report.
Topics: Buprenorphine, Naloxone Drug Combination; Drug Overdose; Fentanyl; First Aid; Heroin; Heroin Dependence; Humans; Illicit Drugs; Male; Naloxone; Nasal Sprays; Recurrence; Veterans | 2015 |
Opioid intoxications involving butyrfentanyl, 4-fluorobutyrfentanyl, and fentanyl from the Swedish STRIDA project.
Topics: Adult; Analgesics, Opioid; Apnea; Chromatography, Liquid; Dose-Response Relationship, Drug; Emergency Service, Hospital; Fentanyl; Humans; Illicit Drugs; Intensive Care Units; Male; Mass Spectrometry; Naloxone; Respiratory Insufficiency; Retrospective Studies; Sweden; Unconsciousness; Young Adult | 2015 |
Agonist stimulation at human μ opioid receptors in a [(35)S]GTPγS incorporation assay: observation of "bell-shaped" concentration-response relationships under conditions of strong receptor G protein coupling.
Topics: Animals; Cricetinae; Cricetulus; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Fentanyl; Gene Expression Regulation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Humans; Morphine; Naloxone; Receptors, Opioid, mu; Sodium | 2016 |
The Changing Use of Intravenous Opioids in an Emergency Department.
Topics: Adult; Analgesics, Opioid; Drug Utilization; Emergency Service, Hospital; Emergency Treatment; Female; Fentanyl; Humans; Hydromorphone; Infusions, Intravenous; Male; Middle Aged; Morphine; Naloxone; Retrospective Studies; Trauma Centers | 2015 |
The Effects of Fentanyl on Hepatic Mitochondrial Function.
Topics: Adenosine Triphosphate; Analgesics, Opioid; ATP Binding Cassette Transporter, Subfamily B; Cell Respiration; Decanoic Acids; Dose-Response Relationship, Drug; Electron Transport Chain Complex Proteins; Energy Metabolism; Fentanyl; Hep G2 Cells; Humans; Hydroxy Acids; Mitochondria, Liver; Naloxone; Narcotic Antagonists; Oxygen Consumption; Potassium Channel Blockers; Potassium Channels | 2016 |
Fentanyl misuse.
Topics: Analgesics, Opioid; Canada; Drug Overdose; Fentanyl; Humans; Naloxone; Narcotic Antagonists; Opioid-Related Disorders | 2016 |
Fatal Fentanyl: One Pill Can Kill.
Topics: Acetaminophen; Adult; Analgesics, Opioid; California; Drug Combinations; Emergency Service, Hospital; Female; Fentanyl; Humans; Hydrocodone; Illicit Drugs; Male; Middle Aged; Naloxone | 2017 |
Effects of naloxone on motion sickness in cats alone and with broad spectrum antiemetics.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antiemetics; Cats; Dose-Response Relationship, Drug; Drug Interactions; Emetics; Female; Fentanyl; Models, Animal; Motion Sickness; Naloxone; Neurokinin-1 Receptor Antagonists; Physical Stimulation; Piperidines; Vomiting | 2017 |
Intranasal Opioid Administration in Rhesus Monkeys: PET Imaging and Antinociception.
Topics: Administration, Intranasal; Analgesics, Opioid; Animals; Behavior, Animal; Fentanyl; Injections, Intramuscular; Macaca mulatta; Male; Naloxone; Nociception; Positron-Emission Tomography | 2016 |
Letters.
Topics: Administration, Inhalation; Adult; Analgesics, Opioid; Coma; Drug Packaging; Fentanyl; Humans; Male; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Pneumonia; Respiration, Artificial | 2016 |
Use of naloxone to minimize extubation failure after premedication for INSURE procedure in preterm neonates.
Topics: Adjuvants, Anesthesia; Airway Extubation; Analgesics, Opioid; Atropine; Continuous Positive Airway Pressure; Female; Fentanyl; Humans; Infant, Extremely Premature; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Intubation, Intratracheal; Male; Naloxone; Narcotic Antagonists; Neuromuscular Depolarizing Agents; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Respiratory Insufficiency; Succinylcholine | 2016 |
"Jaws of Steel" After Very Low Dose of Fentanyl During Prebronchoscopy Sedation.
Topics: Administration, Intravenous; Bronchoscopy; Conscious Sedation; Fentanyl; Humans; Male; Middle Aged; Naloxone; Opioid-Related Disorders; Treatment Outcome | 2017 |
Multiple Fentanyl Overdoses - New Haven, Connecticut, June 23, 2016.
Topics: Adult; Aged; Connecticut; Drug Overdose; Emergency Service, Hospital; Fatal Outcome; Female; Fentanyl; Humans; Male; Middle Aged; Naloxone | 2017 |
Addressing the Fentanyl Threat to Public Health.
Topics: Analgesics, Opioid; Drug and Narcotic Control; Drug Overdose; Fentanyl; Humans; Illicit Drugs; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Public Health; United States | 2017 |
Fentanyl laced heroin and its contribution to a spike in heroin overdose in Miami-Dade County.
Topics: Cross-Sectional Studies; Drug Overdose; Emergency Service, Hospital; Fentanyl; Florida; Heroin; Humans; Naloxone; Narcotic Antagonists; Retrospective Studies | 2017 |
Intoxications involving acrylfentanyl and other novel designer fentanyls - results from the Swedish STRIDA project.
Topics: Adult; Analgesics, Opioid; Antidotes; Chromatography, Liquid; Designer Drugs; Emergency Service, Hospital; Female; Fentanyl; Humans; Illicit Drugs; Intensive Care Units; Internet; Male; Mass Spectrometry; Middle Aged; Naloxone; Poison Control Centers; Substance Abuse Detection; Sweden; Young Adult | 2017 |
Abuse of fentanyl derivatives: History repeating itself.
Topics: Analgesics, Opioid; Counterfeit Drugs; Fentanyl; History, 20th Century; History, 21st Century; Humans; Illicit Drugs; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; United States | 2017 |
Characteristics of Fentanyl Overdose - Massachusetts, 2014-2016.
Topics: Adolescent; Adult; Age Distribution; Analgesics, Opioid; Drug Overdose; Ethnicity; Female; Fentanyl; Humans; Illicit Drugs; Male; Massachusetts; Middle Aged; Naloxone; Risk Factors; Sex Distribution; White People; Young Adult | 2017 |
Syndrome surveillance of fentanyl-laced heroin outbreaks: Utilization of EMS, Medical Examiner and Poison Center databases.
Topics: Chicago; Coroners and Medical Examiners; Cross-Sectional Studies; Databases, Factual; Disease Outbreaks; Drug Contamination; Drug Overdose; Emergency Medical Services; Fentanyl; Heroin; Humans; Illinois; Naloxone; Narcotic Antagonists; Narcotics; Poison Control Centers; Retrospective Studies | 2017 |
Use of naloxone nasal spray 4 mg in the community setting: a survey of use by community organizations.
Topics: Administration, Intranasal; Adolescent; Adult; Analgesics, Opioid; Drug Overdose; Female; Fentanyl; Humans; Male; Naloxone; Narcotic Antagonists; Nasal Sprays; Surveys and Questionnaires; Young Adult | 2018 |
Risk factors for severe respiratory depression from prescription opioid overdose.
Topics: Adult; Age Factors; Analgesics, Opioid; Cohort Studies; Drug Overdose; Emergency Service, Hospital; Female; Fentanyl; Humans; Intubation, Intratracheal; Male; Methadone; Middle Aged; Multivariate Analysis; Naloxone; Narcotic Antagonists; Odds Ratio; Oxycodone; Prescription Drug Misuse; Prospective Studies; Respiration, Artificial; Respiratory Insufficiency; Risk Factors; Severity of Illness Index; United States | 2018 |
Acute and painful exacerbation of RLS and PLM induced by opioid interaction - withdrawal syndrome.
Topics: Aged, 80 and over; Analgesics, Opioid; Drug Combinations; Fentanyl; Humans; Male; Naloxone; Nocturnal Myoclonus Syndrome; Osteoarthritis, Knee; Restless Legs Syndrome; Self Medication; Substance Withdrawal Syndrome; Tilidine | 2017 |
Serotonergic medications, herbal supplements, and perioperative serotonin syndrome.
Topics: Aged; Curcuma; Dietary Supplements; Drug Interactions; Fentanyl; Fluoxetine; Humans; Male; Midazolam; Naloxone; Perioperative Period; Serotonin Agents; Serotonin Syndrome; Time Factors; Trazodone; Young Adult | 2017 |
Self-identification of nonpharmaceutical fentanyl exposure following heroin overdose.
Topics: Adolescent; Adult; Cross-Sectional Studies; Drug Overdose; Emergency Service, Hospital; Fentanyl; Heroin; Humans; Naloxone; Self Report; Young Adult | 2018 |
Naloxone for heroin, prescription opioid, and illicitly made fentanyl overdoses: Challenges and innovations responding to a dynamic epidemic.
Topics: Analgesics, Opioid; Community Health Services; Drug Overdose; Fentanyl; Heroin; Heroin Dependence; Humans; Illicit Drugs; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Substance-Related Disorders | 2017 |
ACMT and AACT Position Statement: Preventing Occupational Fentanyl and Fentanyl Analog Exposure to Emergency Responders.
Topics: Analgesics, Opioid; Emergency Responders; Eye Protective Devices; Fentanyl; Gloves, Protective; Humans; Inhalation Exposure; Naloxone; Narcotic Antagonists; National Academy of Sciences, U.S.; Occupational Exposure; Opioid-Related Disorders; Respiratory Protective Devices; United States | 2017 |
Controversies and carfentanil: We have much to learn about the present state of opioid poisoning.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Health Knowledge, Attitudes, Practice; Hospital Rapid Response Team; Humans; Law Enforcement; Naloxone; Narcotic Antagonists; North America; Opioid-Related Disorders; Pharmacovigilance; Police; Prescription Drug Misuse | 2017 |
ACMT and AACT position statement: preventing occupational fentanyl and fentanyl analog exposure to emergency responders.
Topics: Emergency Responders; Fentanyl; Humans; Inhalation Exposure; Naloxone; Occupational Exposure; Risk Factors; Societies, Medical | 2018 |
Opioid Overdose Outbreak - West Virginia, August 2016.
Topics: Adolescent; Adult; Analgesics, Opioid; Designer Drugs; Disease Outbreaks; Drug Overdose; Emergency Medical Services; Female; Fentanyl; Humans; Male; Middle Aged; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; West Virginia; Young Adult | 2017 |
Fentanyl's Role in Opioid Overdose Deaths.
Topics: Analgesics, Opioid; Drug Overdose; Female; Fentanyl; Humans; Male; Naloxone; Narcotic Antagonists; Nurse-Patient Relations; Opioid-Related Disorders | 2017 |
A Novel Oral Fluid Assay (LC-QTOF-MS) for the Detection of Fentanyl and Clandestine Opioids in Oral Fluid After Reported Heroin Overdose.
Topics: Adolescent; Analgesics, Opioid; Chromatography, Liquid; Drug Contamination; Drug Overdose; Emergency Service, Hospital; Female; Fentanyl; Heroin Dependence; Humans; Male; Mass Spectrometry; Naloxone; Narcotic Antagonists; Predictive Value of Tests; Prospective Studies; Reproducibility of Results; Saliva; Substance Abuse Detection; Urinalysis; Young Adult | 2017 |
Underlying Factors in Drug Overdose Deaths.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Heroin Dependence; Humans; Illicit Drugs; Mortality; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; United States | 2017 |
Accessibility of axonal G protein coupled mu-opioid receptors requires conceptual changes of axonal membrane targeting for pain modulation.
Topics: Analgesics, Opioid; Animals; Axons; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Fentanyl; Freund's Adjuvant; Inflammation; Male; Naloxone; Narcotic Antagonists; Neuralgia; Rats, Wistar; Receptors, Opioid, mu; Sciatic Nerve | 2017 |
Analysis of the Efficiency of Microencapsulated Sustained-Release Form of Naloxone on the Experimental Model of Fentanyl Poisoning.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Alginates; Animals; Animals, Outbred Strains; Carboxymethylcellulose Sodium; Drug Carriers; Drug Compounding; Drug Liberation; Fentanyl; Glucuronic Acid; Hexuronic Acids; Kinetics; Male; Naloxone; Narcotic Antagonists; Narcotics; Polyesters; Rats; Respiration | 2017 |
Alberta's provincial take-home naloxone program: A multi-sectoral and multi-jurisdictional response to overdose.
Topics: Alberta; Community Health Services; Drug Overdose; Fentanyl; Harm Reduction; Humans; Naloxone; Narcotic Antagonists; Program Evaluation | 2017 |
Case 37-2017. A 36-Year-Old Man with Unintentional Opioid Overdose.
Topics: Adult; Analgesics, Opioid; Drug Overdose; Fentanyl; Heroin; Heroin Dependence; Humans; Hypoxia; Lung; Male; Naloxone; Narcotic Antagonists; Pulmonary Edema; Radiography, Thoracic; Substance Abuse, Intravenous | 2017 |
Opioids and Chest Wall Rigidity During Mechanical Ventilation.
Topics: Analgesics, Opioid; Female; Fentanyl; Humans; Middle Aged; Muscle Rigidity; Naloxone; Narcotic Antagonists; Respiration, Artificial; Respiratory Muscles; Risk Factors; Thoracic Wall | 2018 |
Risk of fentanyl-involved overdose among those with past year incarceration: Findings from a recent outbreak in 2014 and 2015.
Topics: Adolescent; Adult; Drug Overdose; Female; Fentanyl; Humans; Illicit Drugs; Male; Naloxone; Rhode Island; Risk; Young Adult | 2018 |
Amount of naloxone used to reverse opioid overdoses outside of medical practice in a city with increasing illicitly manufactured fentanyl in illicit drug supply.
Topics: Analgesics, Opioid; Cities; Dose-Response Relationship, Drug; Drug Overdose; Fentanyl; Humans; Illicit Drugs; Naloxone; Narcotic Antagonists | 2019 |
Efficacy and Safety of Sublingual Fentanyl Tablets in Breakthrough Cancer Pain Management According to Cancer Stage and Background Opioid Medication.
Topics: Administration, Sublingual; Aged; Analgesics, Opioid; Breakthrough Pain; Drug Combinations; Drug Therapy, Combination; Female; Fentanyl; Humans; Male; Naloxone; Neoplasm Staging; Neoplasms; Oxycodone; Pain Management; Quality of Life; Treatment Outcome | 2018 |
Opioid analgesia on the battlefield: a retrospective review of data from Operation HERRICK.
Topics: Adolescent; Adult; Afghan Campaign 2001-; Afghanistan; Analgesics, Opioid; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Utilization; Fentanyl; Humans; Middle Aged; Morphine; Naloxone; Pain; Registries; Retrospective Studies; United Kingdom; Wounds and Injuries; Young Adult | 2018 |
Distribution of take-home opioid antagonist kits during a synthetic opioid epidemic in British Columbia, Canada: a modelling study.
Topics: Analgesics, Opioid; Bayes Theorem; British Columbia; Drug Overdose; Epidemics; Fentanyl; Harm Reduction; Humans; Illicit Drugs; Naloxone; Narcotic Antagonists; Program Evaluation | 2018 |
Community-Based Response to Fentanyl Overdose Outbreak, San Francisco, 2015.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Community Health Services; Disease Outbreaks; Drug Overdose; Female; Fentanyl; Humans; Male; Middle Aged; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; San Francisco | 2019 |
Analgesic effects of systemic fentanyl on cancer pain are mediated by not only central but also peripheral opioid receptors in mice.
Topics: Action Potentials; Analgesics, Opioid; Animals; Cancer Pain; Cell Line, Tumor; Disease Models, Animal; Fentanyl; Humans; Hyperalgesia; Injections, Intramuscular; Injections, Intravenous; Male; Melanoma; Mice; Mice, Inbred C57BL; Naloxone; Narcotic Antagonists; Quaternary Ammonium Compounds; Receptors, Opioid; Receptors, Opioid, mu; Skin; Skin Neoplasms; Spinal Cord; Tibial Nerve; Xenograft Model Antitumor Assays | 2018 |
At-a-glance - Lessons learned from launching the Manitoba Take-Home Naloxone Program.
Topics: Adolescent; Adult; Analgesics, Opioid; Child; Drug Overdose; Female; Fentanyl; Humans; Male; Manitoba; Naloxone; Narcotic Antagonists; Program Evaluation; Recurrence; Sex Factors; Young Adult | 2018 |
Fentanyl and naloxone effects on glutamate and GABA release rates from anterior hypothalamus in freely moving rats.
Topics: Animals; Fentanyl; gamma-Aminobutyric Acid; Glutamic Acid; Hypothalamus, Anterior; Male; Naloxone; Rats; Rats, Wistar | 2018 |
Effects of transdermal fentanyl solution application and subsequent naloxone hydrochloride administration on minimum alveolar concentration of isoflurane in dogs.
Topics: Analgesics, Opioid; Animals; Dogs; Female; Fentanyl; Isoflurane; Male; Naloxone; Narcotic Antagonists; Pulmonary Alveoli; Reference Values; Transdermal Patch | 2018 |
Can't take the heat: sauna and Fentanyl patch intoxication.
Topics: Aged, 80 and over; Analgesics, Opioid; Emergency Medical Services; Fentanyl; Hot Temperature; Humans; Male; Naloxone; Narcotic Antagonists; Steam Bath; Transdermal Patch | 2019 |
How digital drug users could help to halt the US opioid epidemic.
Topics: Computer Simulation; Drug Overdose; Drug Tolerance; Drug Users; Drug Utilization; Emergency Service, Hospital; Facilities and Services Utilization; Female; Fentanyl; Heroin; Heroin Dependence; HIV Infections; Humans; Models, Psychological; Naloxone; Opioid-Related Disorders; Prescription Drugs; Rural Population; Social Networking; Unemployment; United States; Video Recording | 2018 |
Addressing the Fentanyl Analogue Epidemic by Multiplex UHPLC-MS/MS Analysis of Whole Blood.
Topics: Analgesics, Opioid; Chromatography, High Pressure Liquid; Fentanyl; Humans; Liquid-Liquid Extraction; Molecular Structure; Naloxone; Narcotic Antagonists; Substance Abuse Detection; Tandem Mass Spectrometry | 2018 |
Evaluation of a fentanyl drug checking service for clients of a supervised injection facility, Vancouver, Canada.
Topics: Analgesics, Opioid; British Columbia; Cross-Sectional Studies; Drug Contamination; Drug Overdose; Fentanyl; Harm Reduction; Heroin; Humans; Illicit Drugs; Naloxone; Narcotic Antagonists; Needle-Exchange Programs; Opioid-Related Disorders; Reagent Strips; Substance Abuse, Intravenous | 2018 |
Safety of a Modified Community Trailer to Manage Patients with Presumed Fentanyl Overdose.
Topics: Adult; Analgesics, Opioid; Drug Overdose; Emergency Service, Hospital; Female; Fentanyl; Humans; Male; Middle Aged; Naloxone; Narcotic Antagonists; Opioid-Related Disorders | 2019 |
Characterizing fentanyl-related overdoses and implications for overdose response: Findings from a rapid ethnographic study in Vancouver, Canada.
Topics: Adult; Aged; Analgesics, Opioid; British Columbia; Drug Overdose; Female; Fentanyl; Humans; Male; Middle Aged; Naloxone; Young Adult | 2018 |
Safety of a Brief Emergency Department Observation Protocol for Patients With Presumed Fentanyl Overdose.
Topics: Drug Overdose; Emergency Service, Hospital; Fentanyl; Humans; Naloxone | 2019 |
Unusual case of transdermal fentanyl in cachexia.
Topics: Analgesics, Opioid; Cachexia; Female; Fentanyl; Hospices; Humans; Middle Aged; Naloxone; Narcotic Antagonists; Pain; Pressure Ulcer; Skin Absorption; Transdermal Patch | 2019 |
Perspectives on rapid fentanyl test strips as a harm reduction practice among young adults who use drugs: a qualitative study.
Topics: Adolescent; Adult; Analgesics, Opioid; Drug Overdose; Female; Fentanyl; Follow-Up Studies; Harm Reduction; Hematologic Tests; Humans; Male; Naloxone; Narcotic Antagonists; Narcotic-Related Disorders; Pilot Projects; Reagent Strips; Retrospective Studies; Rhode Island; Substance-Related Disorders; Young Adult | 2019 |
Phosphorylation-deficient G-protein-biased μ-opioid receptors improve analgesia and diminish tolerance but worsen opioid side effects.
Topics: Analgesia; Analgesics, Opioid; Animals; beta-Arrestins; Brain; Drug Tolerance; Female; Fentanyl; Gene Expression; Gene Knock-In Techniques; Infusion Pumps, Implantable; Male; Mice; Mice, Transgenic; Microtomy; Morphine; Naloxone; Pain; Pain Management; Phosphorylation; Protein Binding; Receptors, Opioid, mu; Tissue Culture Techniques | 2019 |
Correlates of seeking emergency medical help in the event of an overdose in British Columbia, Canada: Findings from the Take Home Naloxone program.
Topics: Adult; British Columbia; Cross-Sectional Studies; Drug Overdose; Emergency Medical Dispatch; Female; Fentanyl; Humans; Male; Naloxone; Narcotic Antagonists; Opioid-Related Disorders | 2019 |
Higher doses of naloxone are needed in the synthetic opiod era.
Topics: Dose-Response Relationship, Drug; Drug Overdose; Fentanyl; Humans; Naloxone; Narcotic Antagonists; Narcotics | 2019 |
Suppression of Human Natural Killer Cells by Different Classes of Opioids.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Anesthesia; Buprenorphine; Enkephalin, D-Penicillamine (2,5)-; Fentanyl; Fluoresceins; Humans; Immunosuppression Therapy; K562 Cells; Killer Cells, Natural; Loperamide; Methadone; Morphinans; Morphine; Naloxone; Naltrexone; Succinimides; Toll-Like Receptor 4; Tramadol | 2019 |
How the complex pharmacology of the fentanyls contributes to their lethality.
Topics: Drug Overdose; Fentanyl; Humans; Muscle Rigidity; Naloxone; Narcotic Antagonists; Narcotics; Receptors, Opioid, mu; Respiratory Insufficiency; Respiratory Muscles | 2019 |
Losing the uphill battle? Emergent harm reduction interventions and barriers during the opioid overdose crisis in Canada.
Topics: Canada; Drug Overdose; Fentanyl; Harm Reduction; Humans; Naloxone; Narcotic Antagonists; Opioid Epidemic; Opioid-Related Disorders; Politics | 2019 |
Placental trophoblast transfer of opioids following exposures to individual or mixtures of opioids
Topics: Analgesics, Opioid; Female; Fentanyl; Gas Chromatography-Mass Spectrometry; Heroin; Humans; Maternal-Fetal Exchange; Methadone; Morphine; Naloxone; Oxycodone; Placenta; Pregnancy; Trophoblasts | 2019 |
Suspected involvement of fentanyl in prior overdoses and engagement in harm reduction practices among young adults who use drugs.
Topics: Cross-Sectional Studies; Drug Overdose; Female; Fentanyl; Harm Reduction; Humans; Male; Motivation; Naloxone; Patient Acceptance of Health Care; Reagent Strips; Recurrence; Self Administration; Substance-Related Disorders; Young Adult | 2019 |
Would you be able to recognize the signs and symptoms of this particular drug overdose?
Topics: Adult; Benzodiazepines; Cocaine; Diagnosis, Differential; Drug Overdose; Fentanyl; Heroin; Humans; Male; Middle Aged; Naloxone; Narcotic Antagonists | 2019 |
Urban, individuals of color are impacted by fentanyl-contaminated heroin.
Topics: Adult; Aged; Drug Contamination; Drug Overdose; Female; Fentanyl; Heroin; Heroin Dependence; Humans; Interviews as Topic; Male; Middle Aged; Naloxone; Narcotic Antagonists; Racial Groups; Substance Abuse, Intravenous; United States; Urban Population; Young Adult | 2019 |
Modulation of μ-opioid receptor activation by acidic pH is dependent on ligand structure and an ionizable amino acid residue.
Topics: Cells, Cultured; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Fentanyl; HEK293 Cells; Histamine; Humans; Hydrogen-Ion Concentration; Ligands; Molecular Structure; Mutation; Naloxone; Receptors, Opioid, mu; Signal Transduction; Structure-Activity Relationship | 2019 |
Opioid modulation of cochlear auditory responses in the rat inner ear.
Topics: Action Potentials; Analgesics, Opioid; Animals; Cochlea; Evoked Potentials, Auditory, Brain Stem; Fentanyl; Morphine; Naloxone; Narcotic Antagonists; Otoacoustic Emissions, Spontaneous; Rats; Rats, Long-Evans; Tramadol | 2020 |
Naloxone Dosing After Opioid Overdose in the Era of Illicitly Manufactured Fentanyl.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Drug Dosage Calculations; Drug Overdose; Emergency Service, Hospital; Female; Fentanyl; Humans; Male; Middle Aged; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Retrospective Studies; Substance Abuse Detection; Treatment Outcome; Urinalysis; Young Adult | 2020 |
Changes in murine respiratory dynamics induced by aerosolized carfentanil inhalation: Efficacy of naloxone and naltrexone.
Topics: Administration, Inhalation; Aerosols; Analgesics, Opioid; Animals; Computer Simulation; Dose-Response Relationship, Drug; Fentanyl; Humans; Lung; Male; Mice; Models, Biological; Naloxone; Naltrexone; Narcotic Antagonists; Plethysmography, Whole Body; Respiration; Respiratory Insufficiency; Risk Assessment | 2019 |
Infant and Toddler Ingestion of Illicit Fentanyl: A Case Series.
Topics: Analgesics, Opioid; Cardiopulmonary Resuscitation; Child Abuse; Child, Preschool; Drug Overdose; Female; Fentanyl; Foster Home Care; Humans; Illicit Drugs; Infant; Naloxone; Narcotic Antagonists; Retrospective Studies | 2019 |
Higher naloxone dosing may be required for opioid overdose.
Topics: Adult; Analgesics, Opioid; Cardiopulmonary Resuscitation; Cyanosis; Drug Overdose; Female; Fentanyl; Hospitals, Community; Humans; Male; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Schizophrenia; Substance-Related Disorders | 2019 |
Characteristics and circumstances of heroin and pharmaceutical opioid overdose deaths: Comparison across opioids.
Topics: Adolescent; Adult; Analgesics, Opioid; Australia; Chronic Pain; Drug Overdose; Drug Prescriptions; Female; Fentanyl; Heroin; Humans; Male; Methadone; Middle Aged; Morphine; Naloxone; Opioid-Related Disorders; Tramadol; Young Adult | 2019 |
Racial differences in overdose events and polydrug detection in Indianapolis, Indiana.
Topics: Adult; Black or African American; Cocaine; Drug Overdose; Drug Utilization; Emergency Medical Services; Female; Fentanyl; Humans; Indiana; Male; Naloxone; Urban Population; White People | 2020 |
Comparing rates and characteristics of ambulance attendances related to extramedical use of pharmaceutical opioids in Victoria, Australia from 2013 to 2018.
Topics: Adolescent; Adult; Aged; Ambulances; Analgesics, Opioid; Child; Codeine; Drug Overdose; Emergency Medical Services; Female; Fentanyl; Humans; Male; Middle Aged; Morphine; Naloxone; Oxycodone; Practice Patterns, Physicians'; Prescription Drug Misuse; Retrospective Studies; Victoria; Young Adult | 2020 |
The role of mathematical modelling in aiding public health policy decision-making: A case study of the BC opioid overdose emergency.
Topics: Analgesics, Opioid; British Columbia; Drug Overdose; Fentanyl; Health Policy; Humans; Naloxone; Opiate Overdose; Opioid-Related Disorders | 2021 |
Acute severe intoxication with cyclopropylfentanyl, a novel synthetic opioid.
Topics: Administration, Intranasal; Adult; Aerosols; Analgesics, Opioid; Chromatography, High Pressure Liquid; Drug Overdose; Fentanyl; Humans; Male; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Predictive Value of Tests; Severity of Illness Index; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Tandem Mass Spectrometry; Treatment Outcome | 2020 |
Severe Hypoxemia Prevents Spontaneous and Naloxone-induced Breathing Recovery after Fentanyl Overdose in Awake and Sedated Rats.
Topics: Analgesics, Opioid; Animals; Fentanyl; Hypnotics and Sedatives; Hypoxia; Male; Naloxone; Narcotic Antagonists; Random Allocation; Rats; Rats, Sprague-Dawley; Recovery of Function; Severity of Illness Index; Wakefulness | 2020 |
Effect of positive urine fentanyl screen on attitudes toward heroin use.
Topics: Adult; Analgesics, Opioid; Drug Overdose; Emergency Service, Hospital; Female; Fentanyl; Health Knowledge, Attitudes, Practice; Heroin; Heroin Dependence; Humans; Male; Middle Aged; Naloxone; Opioid-Related Disorders; Retrospective Studies; Risk Reduction Behavior; Surveys and Questionnaires; Young Adult | 2020 |
A Case for Experiential Expertise in Opioid Overdose Surveillance.
Topics: Drug Overdose; Fentanyl; Humans; Illinois; Naloxone; Substance-Related Disorders | 2020 |
The Effects of Intramuscular Naloxone Dose on Mu Receptor Displacement of Carfentanil in Rhesus Monkeys.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Female; Fentanyl; Injections, Intramuscular; Macaca mulatta; Naloxone; Positron-Emission Tomography; Receptors, Opioid, mu | 2020 |
Opioid agonist treatment and risk of mortality during opioid overdose public health emergency: population based retrospective cohort study.
Topics: Adolescent; Adult; British Columbia; Buprenorphine; Cause of Death; Cohort Studies; Emergencies; Female; Fentanyl; Humans; Illicit Drugs; Male; Methadone; Middle Aged; Mortality; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Public Health; Retrospective Studies; Risk Assessment; Young Adult | 2020 |
Tackling the overdose crisis: The role of safe supply.
Topics: Analgesics, Opioid; Canada; Drug Overdose; Fentanyl; Humans; Naloxone; North America; United States | 2020 |
Fentanyl but not Morphine Interacts with Nonopioid Recombinant Human Neurotransmitter Receptors and Transporters.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Cell Line; CHO Cells; Cricetulus; Fentanyl; HEK293 Cells; Humans; Morphine; Naloxone; Narcotic Antagonists; Neurotransmitter Agents; Rats; Receptors, Neurotransmitter; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2020 |
Higher naloxone dosing in a quantitative systems pharmacology model that predicts naloxone-fentanyl competition at the opioid mu receptor level.
Topics: Analgesics, Opioid; Binding, Competitive; Computer Simulation; Dose-Response Relationship, Drug; Drug Overdose; Fentanyl; Humans; Models, Theoretical; Naloxone; Narcotic Antagonists; Receptors, Opioid, mu; Treatment Outcome | 2020 |
Changes in drug use behaviors coinciding with the emergence of illicit fentanyl among people who use drugs in Vancouver, Canada.
Topics: Adult; Analgesics, Opioid; British Columbia; Cross-Sectional Studies; Drug Overdose; Drug Users; Female; Fentanyl; Humans; Illicit Drugs; Male; Middle Aged; Naloxone; Prevalence; Prospective Studies; Substance Abuse, Intravenous; Substance-Related Disorders | 2020 |
The dawn of a new synthetic opioid era: the need for innovative interventions.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Heroin; Humans; Illicit Drugs; Naloxone | 2021 |
Engagement in Harm Reduction Strategies After Suspected Fentanyl Contamination Among Opioid-Dependent Individuals.
Topics: Analgesics, Opioid; Cross-Sectional Studies; Drug Overdose; Female; Fentanyl; Harm Reduction; Humans; Male; Naloxone; Opioid-Related Disorders; United States | 2021 |
Physical Compatibility and Chemical Stability of Fentanyl and Naloxone Hydrochloride in 0.9% Sodium Chloride Injection Solution for Patient-Controlled Analgesia Administration.
Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Chromatography, High Pressure Liquid; Drug Incompatibility; Drug Packaging; Drug Stability; Fentanyl; Injections, Intravenous; Naloxone; Narcotic Antagonists; Reference Standards; Reproducibility of Results; Saline Solution | 2020 |
A low pKa ligand inhibits cancer-associated pain in mice by activating peripheral mu-opioid receptors.
Topics: Analgesics, Opioid; Animals; Bone Neoplasms; Cancer Pain; Cell Line, Tumor; Fentanyl; Hydrogen-Ion Concentration; Hyperalgesia; Ligands; Male; Melanoma, Experimental; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Receptors, Opioid, mu | 2020 |
Divergent profiles of fentanyl withdrawal and associated pain in mice and rats.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Female; Fentanyl; Humans; Hyperalgesia; Locomotion; Male; Mice; Mice, Inbred C57BL; Naloxone; Narcotic Antagonists; Narcotics; Pain; Rats; Rats, Wistar; Substance Withdrawal Syndrome | 2021 |
Fentanyl-contaminated cocaine outbreak with laboratory confirmation in New York City in 2019.
Topics: Adult; Cocaine; Drug Overdose; Emergency Service, Hospital; Female; Fentanyl; Humans; Illicit Drugs; Laboratories; Male; Naloxone; Narcotic Antagonists; New York City; Opioid-Related Disorders | 2021 |
The fentanyl phase of the opioid epidemic in Cuyahoga County, Ohio, United States.
Topics: Adult; Age Distribution; Coroners and Medical Examiners; Drug Overdose; Drug Prescriptions; Female; Fentanyl; Heroin; Humans; Illicit Drugs; Male; Middle Aged; Naloxone; Narcotic Antagonists; Ohio; Opioid-Related Disorders; Racial Groups; Sex Distribution | 2021 |
Characterization of opioidergic mechanisms related to the anti-migraine effect of vagus nerve stimulation.
Topics: Action Potentials; Analgesics, Opioid; Animals; Fentanyl; Migraine Disorders; Naloxone; Narcotic Antagonists; Neurons; Rats; Receptors, Opioid; Vagus Nerve Stimulation | 2021 |
Pharmacological characterization of naloxegol: In vitro and in vivo studies.
Topics: Administration, Oral; Analgesics, Opioid; Animals; Behavior, Animal; Calcium; CHO Cells; Constipation; Cricetulus; Fentanyl; Injections, Subcutaneous; Male; Mice; Morphinans; Morphine; Naloxone; Narcotic Antagonists; Pain; Polyethylene Glycols; Receptors, Opioid, mu | 2021 |
Good Samaritan laws and overdose mortality in the United States in the fentanyl era.
Topics: Analgesics, Opioid; Bayes Theorem; Drug Overdose; Fentanyl; Humans; Naloxone; United States | 2021 |
A case of buprenorphine-precipitated withdrawal managed with high-dose buprenorphine.
Topics: Analgesics, Opioid; Buprenorphine; Buprenorphine, Naloxone Drug Combination; Fentanyl; Humans; Naloxone; Substance Withdrawal Syndrome | 2022 |
Sentanyl: a comparison of blood fentanyl concentrations and naloxone dosing after non-fatal overdose.
Topics: Adult; Analgesics, Opioid; Drug Overdose; Fentanyl; Heroin; Humans; Naloxone; Narcotic Antagonists; Pilot Projects | 2022 |
Sodium chloride injection to treat opioid overdose; Does it work? A preclinical study.
Topics: Animals; Dose-Response Relationship, Drug; Fentanyl; Injections, Intravenous; Male; Morphine; Naloxone; Opiate Overdose; Pain Measurement; Rats; Rats, Wistar; Saline Solution, Hypertonic | 2021 |
Fentanyl causes naloxone-resistant vocal cord closure: A platform for testing opioid overdose treatments.
Topics: Analgesics, Opioid; Animals; Drug Overdose; Fentanyl; Naloxone; Narcotic Antagonists; Opiate Overdose; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Vocal Cords | 2021 |
[Overdose from a patch].
Topics: Aged, 80 and over; Analgesics, Opioid; Consciousness Disorders; Drug Overdose; Female; Fentanyl; Humans; Naloxone; Narcotic Antagonists; Transdermal Patch | 2021 |
Challenges with buprenorphine inductions in the context of the fentanyl overdose crisis: A case series.
Topics: Analgesics, Opioid; Buprenorphine; Buprenorphine, Naloxone Drug Combination; Fentanyl; Humans; Naloxone; Narcotic Antagonists; Opiate Overdose; Opiate Substitution Treatment; Opioid-Related Disorders | 2022 |
Respiratory depressant effects of fentanyl analogs are opioid receptor-mediated.
Topics: Animals; Fentanyl; Hypoventilation; Male; Mice; Molecular Structure; Naloxone; Narcotic Antagonists; Plethysmography; Receptors, Opioid, mu; Respiratory Mechanics | 2022 |
Modifying naloxone to reverse fentanyl-induced overdose.
Topics: Animals; Fentanyl; Heart Rate; Naloxone; Rats | 2022 |
Pharmacological Profiling of Antifentanyl Monoclonal Antibodies in Combination with Naloxone in Pre- and Postexposure Models of Fentanyl Toxicity.
Topics: Analgesics, Opioid; Animals; Antibodies, Monoclonal; COVID-19; Drug Overdose; Fentanyl; Humans; Naloxone; Narcotic Antagonists; Pandemics; Rats; Respiratory Insufficiency | 2022 |
The introduction of fentanyl on the US-Mexico border: An ethnographic account triangulated with drug checking data from Tijuana.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Heroin; Humans; Illicit Drugs; Mexico; Naloxone; Powders | 2022 |
Impact of the naloxone standing order on trends in opioid fatal overdose: an ecological analysis.
Topics: Analgesics, Opioid; Drug Overdose; Female; Fentanyl; Humans; Naloxone; Narcotic Antagonists; Opiate Overdose; Opioid-Related Disorders; Standing Orders | 2022 |
Fentanyl overdose concerns among people who inject drugs: The role of sex, racial minority status, and overdose prevention efforts.
Topics: Analgesics, Opioid; Drug Overdose; Drug Users; Ethnic and Racial Minorities; Female; Fentanyl; Heroin; Humans; Male; Naloxone; Opioid-Related Disorders; Substance Abuse, Intravenous | 2023 |
Modeling of overdose and naloxone distribution in the setting of fentanyl compared to heroin.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Heroin; Humans; Naloxone; Narcotic Antagonists; Opiate Overdose | 2022 |
Gaps in naloxone ownership among people who inject drugs during the fentanyl wave of the opioid overdose epidemic in New York City, 2018.
Topics: Analgesics, Opioid; Drug Overdose; Drug Users; Fentanyl; Humans; Naloxone; New York City; Opiate Overdose; Opioid-Related Disorders; Ownership; Substance Abuse, Intravenous; United States | 2022 |
Patient perceptions of higher-dose naloxone nasal spray for opioid overdose.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Humans; Naloxone; Narcotic Antagonists; Nasal Sprays; Opiate Overdose; Opioid-Related Disorders; United States | 2022 |
Naloxone Dosing in the Era of Fentanyl: The Path Widens by Traveling Down It.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Humans; Naloxone; Narcotic Antagonists | 2022 |
Fentanyl induces autism-like behaviours in mice by hypermethylation of the glutamate receptor gene Grin2b.
Topics: Analgesics, Opioid; Animals; Autism Spectrum Disorder; Autistic Disorder; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Female; Fentanyl; Glutamic Acid; Male; Mice; Naloxone; Narcotic Antagonists; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu | 2022 |
Identification of a novel opioid,
Topics: Adult; Alprazolam; Analgesics, Opioid; Benzimidazoles; Cocaine; Codeine; Drug Overdose; Fentanyl; Heroin; Humans; Illicit Drugs; Levamisole; Middle Aged; Naloxone; Narcotic Antagonists; Opiate Overdose; Phenacetin; Prospective Studies; Tramadol | 2022 |
Development of a Translational Model to Assess the Impact of Opioid Overdose and Naloxone Dosing on Respiratory Depression and Cardiac Arrest.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Heart Arrest; Humans; Naloxone; Narcotic Antagonists; Opiate Overdose; Receptors, Opioid; Receptors, Opioid, mu; Respiratory Insufficiency | 2022 |
Intranasal Fentanyl for On-the-Hill Analgesia by Ski Patrol.
Topics: Administration, Intranasal; Analgesia; Analgesics; Analgesics, Opioid; Fentanyl; Humans; Naloxone; Pain; Pain Management; Pain Measurement | 2022 |
Responding to a surge in overdose deaths: perspectives from US syringe services programs.
Topics: Analgesics, Opioid; COVID-19; Drug Overdose; Fentanyl; Humans; Naloxone; Pandemics; Syringes | 2022 |
Stability of Drugs Stored in Helicopters for Use by Emergency Medical Services: A Prospective Observational Study.
Topics: Aircraft; Amiodarone; Chromatography, High Pressure Liquid; Drug Stability; Drug Storage; Emergency Medical Services; Epinephrine; Etomidate; Fentanyl; Humans; Ketamine; Longitudinal Studies; Midazolam; Naloxone; Norepinephrine; Prospective Studies; Rocuronium; Temperature | 2022 |
A novel long-acting formulation of oral buprenorphine/naloxone produces prolonged decreases in fentanyl self-administration by rhesus monkeys.
Topics: Analgesics, Opioid; Animals; Buprenorphine; Buprenorphine, Naloxone Drug Combination; Delayed-Action Preparations; Female; Fentanyl; Macaca mulatta; Male; Naloxone; Narcotic Antagonists; Opioid-Related Disorders | 2022 |
'It's the same thing as giving them CPR training': rural first responders' perspectives on naloxone.
Topics: Analgesics, Opioid; Cardiopulmonary Resuscitation; Drug Overdose; Emergency Responders; Fentanyl; Humans; Naloxone; Narcotic Antagonists; Opiate Overdose; Opioid-Related Disorders | 2022 |
Fentanyl effects on respiratory neuron activity in the dorsolateral pons.
Topics: Analgesics, Opioid; Animals; Apnea; Fentanyl; Naloxone; Neurons; Pons; Rats; Respiration | 2022 |
Outcomes of law enforcement officer administered naloxone.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Humans; Naloxone; Narcotic Antagonists; Opiate Overdose; Police; Retrospective Studies | 2022 |
Opioid Antagonists from the Orvinol Series as Potential Reversal Agents for Opioid Overdose.
Topics: Analgesics, Opioid; Fentanyl; Humans; Naloxone; Narcotic Antagonists; Opiate Overdose; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2022 |
Overdose Experiences among People Who Inject Drugs in West Virginia: Personal Loss, Psychological Distress, Naloxone, and Fentanyl.
Topics: Analgesics, Opioid; Drug Overdose; Drug Users; Fentanyl; Humans; Naloxone; Psychological Distress; Substance Abuse, Intravenous; United States; West Virginia | 2023 |
Fentanyl-induced muscle rigidity in a dog during weaning from mechanical ventilation after emergency abdominal surgery: A case report.
Topics: Abdominal Muscles; Analgesics, Opioid; Animals; Dog Diseases; Dogs; Female; Fentanyl; Muscle Rigidity; Naloxone; Respiration, Artificial | 2023 |
Amphetamines modulate fentanyl-depressed respiration in a bidirectional manner.
Topics: Amphetamine; Analgesics, Opioid; Animals; Central Nervous System Stimulants; Drug Overdose; Fentanyl; Methamphetamine; Mice; Naloxone; Respiration; Respiratory Insufficiency; United States | 2023 |
I Don't Believe a Person Has to Die When Trying to Get High: Overdose Prevention and Response Strategies in Rural Illinois.
Topics: Analgesics, Opioid; Drug Overdose; Drug Users; Fentanyl; Humans; Illinois; Naloxone; Substance Abuse, Intravenous | 2023 |
Assessment of abuse potential of carfentanil.
Topics: Analgesics, Opioid; Animals; Fentanyl; Heroin; Mice; Naloxone; Rats; Substance Withdrawal Syndrome | 2023 |
Binding preference at the μ-opioid receptor underlies distinct pharmacology of cyclopropyl versus valeryl analogs of fentanyl.
Topics: Analgesics, Opioid; Animals; Cricetinae; Cricetulus; Fentanyl; Male; Mice; Naloxone; Receptors, Opioid, mu; Structure-Activity Relationship | 2023 |
A Dose of Truth: A Qualitative Assessment of Reactions to Messages about Fentanyl for People Who Use Drugs.
Topics: Adolescent; Adult; Analgesics, Opioid; Drug Overdose; Fentanyl; Humans; Naloxone; Risk; Young Adult | 2023 |
Illicit Drugs May Contain Veterinary Tranquilizer.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Humans; Illicit Drugs; Naloxone; Xylazine | 2023 |
The pattern of brain oxygen response induced by intravenous fentanyl limits the time window of therapeutic efficacy of naloxone.
Topics: Analgesics, Opioid; Animals; Brain; Fentanyl; Hypoxia; Hypoxia, Brain; Naloxone; Narcotic Antagonists; Oxygen; Rats | 2023 |
A mixed-methods analysis of risk-reduction strategies adopted by syringe services program participants and non-syringe services program participants in New York City.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Humans; Naloxone; New York City; Risk Reduction Behavior | 2023 |
Structure-Kinetics Relationships of Opioids from Metadynamics and Machine Learning Analysis.
Topics: Analgesics, Opioid; Fentanyl; Morphine; Naloxone; Narcotic Antagonists; Receptors, Opioid, mu | 2023 |
Predictors of opioid overdose during the COVID-19 pandemic: The role of relapse, treatment access and nonprescribed buprenorphine/naloxone.
Topics: Analgesics, Opioid; Buprenorphine, Naloxone Drug Combination; COVID-19; Drug Overdose; Fentanyl; Humans; Naloxone; Opiate Overdose; Pandemics; Recurrence | 2023 |
Theophylline reverses oxycodone's but not fentanyl's respiratory depression in mice while caffeine is ineffective against both opioids.
Topics: Analgesics, Opioid; Animals; Caffeine; Fentanyl; Male; Mice; Naloxone; Narcotic Antagonists; Oxycodone; Respiratory Insufficiency; Theophylline | 2023 |
Structure-Activity Relationship Study of Cannabidiol-Based Analogs as Negative Allosteric Modulators of the μ-Opioid Receptor.
Topics: Analgesics, Opioid; Cannabidiol; Fentanyl; Naloxone; Narcotic Antagonists; Receptors, Opioid, mu; Structure-Activity Relationship | 2023 |
Naloxone prescriptions among patients with a substance use disorder and a positive fentanyl urine drug screen presenting to the emergency department.
Topics: Analgesics, Opioid; Cocaine; Drug Overdose; Emergency Service, Hospital; Fentanyl; Humans; Illicit Drugs; Methadone; Naloxone; Opioid-Related Disorders; Prescriptions; Retrospective Studies | 2023 |
Postmortem toxicology findings from the Camden Opioid Research Initiative.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Humans; Naloxone; Opioid-Related Disorders; Pandemics; United States | 2023 |
The Appearance of Xylazine in the United States as a Fentanyl Adulterant.
Topics: Bradycardia; Drug Overdose; Fentanyl; Humans; Naloxone; United States; Xylazine | 2023 |